Authors: John Paul Ortiz Bustillo, Elette Engels, Elrick T. Inocencio, Michael Lerch, Julia Rebecca D Posadas, Anatoly Rosenfeld, Kiarn Roughley, Moeava Tehei, Gordon Wallace, Danielle Warren, Vincent de Rover
Affiliation: Centre for Medical Radiation Physics, University of Wollongong Australia, Department of Radiology, University of the Philippines- Philippine General Hospital, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong Australia, Centre for Medical Radiation Physics, University of Wollongong, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, University of the Philippines Manila; Centre for Medical Radiation Physics, University of Wollongong Australia
Abstract Preview: Purpose: To compare the biological response through cell viability assay and fluorescence imaging of 3D bioprinted brain cancer (glioma) constructs relative to 2D monolayer and 3D spheroid culture for...
Authors: Thomas Gee, Sofia Michopoulou, Amit Nautiyal
Affiliation: University Hospital Southampton
Abstract Preview: Purpose: Dosimetry software that is accessible to departments offers new opportunities to improve patient-specific dosimetry. Prior to clinical decision-making, it is essential to validate dosimetry s...
Authors: Zachary Buchwald, Zach Eidex, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Gadolinium-based contrast agents (GBCA) are commonly used for patients with gliomas to delineate and characterize the brain tumors using T1-weighted (T1W) MRI. However, there is a rising conc...
Authors: Olivier Blasi, Eric Cameron, Brad K. Lofton
Affiliation: CAMP, Colorado Assn in Medical Phys (CAMP)
Abstract Preview: Purpose:
Magnetic Resonance (MR) imaging obtained from external centers for radiation therapy (RT) planning can suffer from suboptimal protocols and geometric distortions. These issues can require ...
Authors: Aditya P. Apte, Xinan Chen, Joseph O. Deasy, Ramesh Paudyal, Kyung Peck, Amita Shukla-Dave, Nathaniel Swinburne, Robert J. Young
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: We apply our novel formulation of unbalanced-regularized-optimal-mass-transport (urOMT) theory to brain DCE-MRI data to quantify and visualize the behaviors of fluid flows in post-treatment f...
Authors: Richard J Barth, Brook Kennedy Byrd, Roberta DiFlorio-Alexander, Misty J Fox, Venkat Krishnaswamy, Keith D. Paulsen, Timothy B Rooney
Affiliation: Cairn Surgical Inc., Dartmouth Health, Thayer School of Engineering, Dartmouth Hitchcock Medical Center, University of Virginia Health, CairnSurgical Inc.
Abstract Preview: Purpose: Supine breast MRI enables precise surgical planning with demonstrated benefit in decreasing positive margin rates during BCS. However, acquiring supine breast MRI scans in a secondary imaging...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose:
Pancreatic cancer poses therapeutic challenges due to the proximity of critical organs, requiring precise radiotherapy. Magnetic resonance (MR)-guided linear accelerators provide daily ima...
Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu
Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust
Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...
Authors: Colin Adam Doyle, Celeste Winters
Affiliation: Department of Diagnostic Radiology, Oregon Health & Science University, School of Medicine, Oregon Health & Science University
Abstract Preview: Purpose: To audit our radioactive iodine (I-131) dosimetry protocol, review dosimetry methods used at other facilities, investigate the clinical impact of I-131 dosimetry at our facility, and test the...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Stella Flampouri, Heng Li, Sarah Quirk, Timothy Ritter, Mihaela Rosu-Bubulac, Toni M. Roth, Michael B. Roumeliotis, Koren Smith, Wade P. Smith
Affiliation: Johns Hopkins University, Virginia Commonwealth University, University of Washington, VCU Health System, UMass Chan Medical School/IROC RI, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Emory University, Brigham and Women's Hospital; Harvard Medical School, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To assess clinical trial reproducibility for translation to standard clinical care in radiation therapy.
Methods: The systematic review adheres to the Preferred Reported Items for Systemat...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis, Hamlet Spears
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the range of motion of abdominal organs using 4D stack-of-stars magnetic resonance (MR) imaging and 4D computed tomography (CT), the current clinical standard. Accurate o...
Authors: Shengwen Deng, Sven L. Gallo, Robert S. Jones, David W. Jordan, Arashdeep Kaur, Aishwarya M. Kulkarni, Quibai Li, William R.M. Pedersen
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University; Department of Radiology, Louis Stokes Cleveland VA Medical Center
Abstract Preview: Purpose:
Y-90 (Yttrium) SIRT radioembolization takes advantage of delivering localized radiation to the liver. Pre-treatment dosimetry is highly dependent on accurate MAA mapping, which may have an...
Authors: Afrouz Ataei, Xinhui Duan, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose:
Electron density (ED) phantoms are crucial for calibrating CT number (HU) to relative ED in treatment planning. This study evaluates the differences in HU-to-ED calibrations between two co...
Authors: Afrouz Ataei, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose: Even though many patients undergo diagnostic CT scans prior to treatment, simulation CT scans are commonly required for treatment planning. This study evaluates whether prior diagnostic CT sc...
Authors: Sang Hee Ahn, Nalee Kim, Do Hoon Lim
Affiliation: Samsung Medical Center, Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine
Abstract Preview: Purpose: MRI offers superior soft-tissue contrast, aiding tumor localization and segmentation in radiation therapy, which traditionally relies on oncologists' expertise. This study compares CNN-based ...
Authors: Hyo-Min Cho, Cheolpyo Hong, Changwoo Lee, Sunyoung Lee
Affiliation: Daegu Catholic University, Korea Research Institute of Standards and Science (KRISS), Korea Research Institute of Standards and Science
Abstract Preview: Purpose: With the increasing prevalence of metabolic syndrome, the importance of diagnosing obesity and fatty liver diseases has grown significantly. As a result, there is a rising demand for non-inva...
Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...
Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo
Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...
Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom
Affiliation: Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School
Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...
Authors: Emily Helen Hayes, Chihray Liu
Affiliation: University of Florida
Abstract Preview: Purpose: To evaluate dosimetric discrepancies in bladder dose calculations among rigid, deformed, and manual contouring methods in prostate cancer patients and assess dose variations resulting from bl...
Authors: Fei Han, James M. Lamb, Michael Vincent Lauria, Daniel A. Low, Tessa Elizabeth Maurer, Danilo Maziero, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Nicolas Viot
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Siemens Healthineers, UCLA, University of California Los Angeles
Abstract Preview: Purpose: Patients with lung disease outside radiotherapy are barred from high dose protocols used for motion modeling, but MRI could offer no-dose alternatives. Image-based ventilation is a promising ...
Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang
Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...
Authors: Emel Calugaru, Jenghwa Chang, Sean T Grace, Nicholas Harvey, Jessica Jung, Ching-Ling Teng
Affiliation: Northwell, Hofstra University, Hofstra University Medical Physics Program
Abstract Preview: Purpose: To evaluate the consistency of MRI distortion corrections across Northwell Health system and evaluate the necessity and importance of distortion QA for MRIs used for stereotactic radiosurgery...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Jing Feng, Wenzheng Feng, Joseph Hanley, Jeff Stainsby, Tingyu Wang
Affiliation: Synaptive Medical, Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose:
The Synaptive MRI is a 0.5T superconducting head only system (first US install 2023). This is the first study that evaluates the geometric accuracy using a Sun Nuclear MR Distortion and Im...
Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner
Affiliation: Harvard–MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: For soft-tissue abdominal tumors, a 4D-MR may provide improved tumor tracking over the clinical standard 4D-CT. This project aims to optimize a clinically available 4D-MR pulse sequence to ac...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...
Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose:
MR-guided adaptive radiation therapy (MRgART) is transforming clinical workflows, requiring fast, accurate organs-at-risk (OARs) contouring. While deep learning auto-segmentation (DLAS) of...
Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou
Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...
Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University
Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...
Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li, Junzhong Xu
Affiliation: Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiology, Vanderbilt University Medical Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cell size is a vital parameter in evaluating the tumor microenvironment, including cell apoptosis and radiotherapy(RT)-induced immune cell infiltration. The IMPULSED(Imaging Microstructural P...
Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...
Authors: B. Gino Fallone, Gawon Han, Keith D. Wachowicz, Mark G. Wright, Eugene Yip, Jihyun Yun
Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com
Abstract Preview: Purpose: MRI-radiotherapy hybrid systems can guide the therapeutic beam, dynamically adjusting to a moving tumor in real-time. However, there is a time delay from imaging and beam control, requiring p...
Authors: Wesley E. Bolch, Emily L. Marshall, Dhanashree Rajderkar, Wyatt Smither
Affiliation: University of Florida
Abstract Preview: Purpose: To determine the accuracy of TotalSegmentator, an AI-based automatic segmentation toolkit, on pediatric CT scans as the original software was trained on adult image datasets with a mean patie...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Lizbeth Ayala-Dominguez, Aaron L Carrel, Diego Hernando, Gabrielle L Hoffmann, Amber Possell, Ivan M. Rosado-Mendez, Jiayi Tang, Andrew Wentland
Affiliation: Department of Pediatrics, University of Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: Metabolic dysfunction-associated steatotic liver disease (MAFLD) is the leading cause of chronic liver disease in children. While biopsy remains the diagnostic standard, non-invasive imaging ...
Authors: Diandra Ayala-Peacock, Junzo Chino, Oana I. Craciunescu, Allison Jones, Kyle J. Lafata, Kim Light, Sheridan G. Meltsner, Jack B Stevens
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke University Medical Center
Abstract Preview: Purpose: This study aims to develop an MR-based method that retrospectively correlates longitudinal changes in morphology and physiology for the bulboclitoris and vaginal canal with dose received duri...
Authors: Ke Lu, Chunhao Wang, Ruoxu Xia, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Lei Zhang, Rihui Zhang, Jingtong Zhao, Haiming Zhu
Affiliation: Duke University, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: The human brain’s spherical geometry offers unique opportunities for improving the segmentation of tiny and irregular anatomical structures. We hypothesize that representing the brain in sphe...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Guillermo Daniel Alvarez, Daniel Fino, Rocio Luz Gilli, Dorian Alexander Romero
Affiliation: School Foundation of Nuclear Medicine, INTECNUS Foundation, Nuclear Medicine and Radiotherapy Center of Southern Patagonia
Abstract Preview: Purpose: To evaluate the anatomical, functional, and molecular information from PET/MR images with F18-PSMA to identify intraprostatic lesions and delineate a boost in stereotactic body radiotherapy (...
Authors: Janet Ching-Mei Feng, Jimmy Huynh
Affiliation: UTHealth McGovern Medical School
Abstract Preview: Purpose: The Image Gently Alliance had provided helpful information to optimize image protocols in pediatric patients since 2007, and our assumption was that newer units could use near-to-optimal prot...
Authors: Darren Fang, Amar Kishan, Justin McWilliams, Dan Ruan, Xiaodong Zhong
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Department of Radiological Sciences, University of California, Los Angeles
Abstract Preview: Purpose: Prostate radiotherapy can malform penile vasculature, contributing to erectile dysfunction and compromising quality of life. To detect, quantify, and preferably avoid such occurrences, this p...
Authors: Yunxiang Li, Weiguo Lu, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Curating high-quality, labeled data for medical image segmentation can be challenging and costly, considering the existence of various image domains with differing modalities/protocols. Cr...