Authors: Ishika Bhaumik, John M. Boone, Michael T Corwin, Eric S Diaz, Ahmadreza Ghasemiesfe, Andrew M. Hernandez, Sarah E. McKenney, Misagh Piran, Ali Uneri, Eric L White
Affiliation: UC Davis, UC Davis Health, University of California, Johns Hopkins Univ
Abstract Preview: Purpose: A new model CT scanner (Canon Aquilion One Insight) was recently installed at our institution, and it included a 3D Landmark (3DLM) scan for automatic scan planning, a new deep learning recon...
Authors: Bas W. Raaymakers, Mario Ries, Paris Tzitzimpasis, Cornel Zachiu
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, University Medical Center Utrecht, UMC Utrecht
Abstract Preview: Purpose: Radiation pneumonitis affects approximately 10-30% of lung cancer patients treated with radiation therapy (RT), posing a significant dose-limiting factor. Recently developed CT-ventilation me...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...
Authors: Huay Din, Grace Jianan Gang, Grace Hyun Kim, Michael F. McNitt-Gray, Joseph W. Stayman, Yijie Yuan
Affiliation: Johns Hopkins University, John Hopkins University, University of Pennsylvania, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose:
Radiomics rely on quantitative features to discern underlying biological signatures. However, feature dependence on the imaging systems themselves hampers the creation of reproducible and ...
Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval
Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...
Authors: Paul L. Carson, Sander Dekker, Stephen Z Pinter, Megan K. Russ
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Michigan, Cablon Medical B.V., Univ of Michigan, Dept. of Radiology
Abstract Preview: Purpose:
To promote a simplified, inexpensive, but rigorous set of ultrasound QA tests and to evaluate their potential using a Randomly-placed very Hypoechoic Sphere Phantom (RHSP) in comparison to...
Authors: Yunxiang Li, Xinlong Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Acquiring high-resolution (HR) proton density (PD) images is time-consuming, while lower-resolution (LR) PD scans are faster but can lack sufficient details. We propose CycleHR, a T2-contrast...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory
Abstract Preview: Purpose:
Dual-layer kV imager (DLI) architecture enables the capability for single-shot dual-energy (DE) intrafraction imaging. As noise from individual DLI layers are primarily uncorrelated, simpl...
Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu
Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell
Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...
Authors: Sulaiman D. Aldoohan, Gerardo Garcia
Affiliation: University of Toledo Medical Center
Abstract Preview: Purpose: To evaluate the noise power spectra (NPS) of images acquired using parallel imaging with varying acceleration factors in 1-D and 3-D spaces and to compare the level of the power of the noise ...
Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantitatively evaluate power-law exponent β as a potential image-based breast cancer risk factor.
Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...
Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang
Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...
Authors: Paul Deak, Yang Li, Mark Pankuch, Yanling Qu, Maggie Stauffer, Hazel Wang
Affiliation: Northwestern Medicine Proton Center, GE, Northwestern Medicine
Abstract Preview: Purpose: The objective is to evaluate Relative Stopping Power(RSP) accuracy of ultra-fast switching KV Dual-Energy CT(DECT) in animal tissue and compare it to the RSP converted from Single Energy CT(S...
Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham
Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona
Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...
Authors: Justus Adamson, Mu Chen, Ke Lu, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Yaogong Zhang, Haipeng Zhao, Haiming Zhu, Yuchun Zhu
Affiliation: Shanghai Dacheng Medical Technology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: In filtered back-projection (FBP) reconstruction, conventional filters often reduce noise at the expense of high-frequency details, leading to structural details loss. To address this limitat...
Authors: Xinyi Fu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...
Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) doses shall be limited for pediatric patients in clinical settings. Device called Filtimator (filter+collimator) was custom designed to reduce setup CB...
Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Massachusetts General Hospital
Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...
Authors: Mustafa Bashir, Diana Kadi, Kyle J. Lafata, Jacob A. Macdonald, Mark Martin, Yuqi Wang, Marilyn Yamamoto
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Electrical and Computer Engineering, Duke University, Department of Radiology, Duke Unversity
Abstract Preview: Purpose: To develop a high-throughput, automated-data-interrogation pipeline for integrating imaging and clinical information to identify key determinants of liver volume (LV), enabling population-sca...
Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese
Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory
Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...
Authors: Beth Reed, Justin B. Solomon
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: The purpose of this study was to compare image quality between CT images of variable slice thickness reconstructed directly at the scanner verses reformatted at a PACS workstation.
Methods...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Jongduk Baek, Jooho Lee, Adam S. Wang
Affiliation: Stanford University, Yonsei University
Abstract Preview: Purpose: Optimizing the balance between radiation dose and image quality in computed tomography (CT) is important for minimizing patient X-ray exposure while maintaining diagnostic accuracy. While rad...
Authors: Mengqi Shen, Meghna Trivedi, Tony J.C. Wang, Andy (Yuanguang) Xu, Yading Yuan
Affiliation: Columbia University Medical Center, Dept of Med Hematology & Oncology, Data Science Institute at Columbia University, Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: T2-weighted (T2w) images are critical for identifying pathological changes due to their superior contrast in differentiating tissue types. However, they often lack detailed anatomical resolut...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Vasantha Vasan, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: Minimizing radiation dose is crucial in CT colonography (CTC) screening and diagnosis. Tin (Sn) prefiltration is readily incorporated into clinical photon-counting CT (PCCT) scanners, yet its...
Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang
Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...
Authors: Cecelia Brewington, Connor Edwards Miles All Leska-Kent, Kyrillos Grace, Katherine Hyde, Sabee Molloi, Shiva Mostafavi, Liqiang Ren, Alireza Shojazadeh, Justin Truong
Affiliation: Department of Radiology, UT Southwestern Medical Center, University of California, Irvine, University of Texas Southwestern
Abstract Preview: Purpose: To retrospectively assess image quality in coronary CT angiography (CCTA) using a patient-specific post-trigger delay (PTD) protocol, developed using half of the injection time plus a dispers...
Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc Laperrière, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Analogic Canada
Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...
Authors: Samuel L. Brady, Kevin Chen, Joseph G. Meier
Affiliation: University of Cincinnati, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose: Conebeam-CT (CBCT) acquisition protocols typically do not distinguish between adults and pediatrics. In collaboration with a fluoroscopically-guided interventional (FGI) manufacturer, new, do...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Alexander Alsalihi, Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The upcoming CMS regulation, titled “Excessive Radiation Dose or Inadequate Image Quality for Diagnostic Computed Tomography (CT) in Adults”, employs two measures, size-adjusted DLP (SAD) and...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Hajar Moradmand, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, University of Maryland, Baltimore County, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: We are developing a novel Compton Camera (CC) system mounted orthogonally on the treatment nozzle for prompt gamma (PG) imaging-based proton range verification during treatment. This study in...
Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson
Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital
Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...
Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou
Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Alex Lindgren-Ruby, Jeffrey M. Moirano, Joseph Everett Wishart
Affiliation: University of Washington
Abstract Preview: Purpose:
To evaluate polynomial fitting of signal intensity for signal-to-noise ratio (SNR) estimation from weekly QC ACR MRI phantom images and compare against other SNR estimation methods as well...
Authors: Caroline Cheney, Patricia G Collins, Allen R. Goode, Preston Le, Andrew M. Polemi, Angela Snyder
Affiliation: UVA Health, Atirix Medical Systems
Abstract Preview: Purpose: Optimize ongoing quality control (QC) for radiographic (DR) and fluoroscopic (FL) systems by identifying metrics most sensitive to hardware disruptions among regional noise, pooled noise, sig...
Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman
Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University
Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...
Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, Humberto Monsivais, John Rong
Affiliation: Purdue University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To investigate the noise characteristics of a clinical photon counting detector CT (PCD-CT) system along axial and through-plane (Z) dimensions using 3D NPS measurements.
Methods: This stu...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...
Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps
Affiliation: University of New Mexico Hospital
Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...
Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Akira Nishikori, Daniel W Shin
Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA
Abstract Preview: Purpose: To validate a simulation tool using physics-based image quality metrics in both phantom and patient data, and to assess the low contrast detectability (LCD) of Super Resolution-Deep Learning ...