Authors: David Chighvinadze, Lisa Czaplicki, Jeremy D. Donaghue, Lama K. Muhieddine Mossolly
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic Strongsville, Cleveland Clinic Fairview
Abstract Preview: Purpose:
Current electron block generation requires manual cutting of stryofoam and placement for pouring of the block which can lead to possible miscutting of blocks, and non-accurate rotations co...
Authors: Brett Bocian, Nesrin Dogan, John C. Ford, Alan Pollack, Ryder Marshall Schmidt, Junwei Shi, Jorge D Vega
Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: X-ray fluorescence computed tomography (XFCT) is an emerging molecular imaging modality gaining attention in cancer theranostics with high-Z metal nanoparticles (MNPs). While XFCT has been de...
Authors: Shashanksharad Kale, Gopishankar Natanasabapathi, Daya Nand Kishore Sharma
Affiliation: All India Institute of Medical Sciences (AIIMS), Department of Radiation Oncology, All India Institute of Medical Sciences
Abstract Preview: Purpose:
The study demonstrates a novel 3D printing method to fabricate an ion chamber insert (ICI) for absolute dosimetry purpose in gamma knife radiosurgery (GKRS).
Methods:
Our institute u...
Authors: Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier
Affiliation: University of Florida
Abstract Preview: Purpose: To develop a tetrahedralizable mesh-type phantom of a male beagle dog to later perform Monte Carlo radiation transport simulations and calculate organ doses using monoenergetic photons, elect...
Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: Cardiorespiratory motion management is crucial in stereotactic arrhythmia radiotherapy to define target margins and minimize cardiac toxicity. While respiratory 4DCT (r4DCT) images can infer ...
Authors: Chuan He, Anh H. Le, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, Cedars-Sinai
Abstract Preview: Purpose: To develop a non-measured and DVH-based (NMDB) IMRT QA framework integrating machine learning (ML) to classify lung SBRT VMAT plans prone to delivery errors
Methods: 560 Eclipse AcurosXB l...
Authors: Wesley E. Bolch, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Lazaro Fuentes Alfonso, Shreya P. Pathak, Julia D. Withrow
Affiliation: University of Florida
Abstract Preview: Purpose: To develop tetrahedral mesh-based tissue models within the breasts of the International Commission on Radiological Protection (ICRP) adult female mesh-type reference computational phantom (AF...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Amir Abdollahi, Celine Karle, Michele M. Kim, Constantinos Koumenis, Andrea Mairani, Erato Stylianou Markidou
Affiliation: Heidelberg Ion-Beam Therapy Center - Department of Radiation Oncology, German Cancer Research Centre(DKFZ), University of Pennsylvania, Physics Dep. University of Cyprus
Abstract Preview: Purpose: The aim is to compare FLASH dose-rate RT generated with protons and carbon (HIT) and compare to protons (UPenn) to provide evidence for equipotency of FLASH vs. standard RT to tumor growth co...
Authors: Matthew Stephen Andriotty, Taoran Cui, Josh Kilian-Meneghin, Ke Nie, Xiao Wang, Zhenyu Xiong, Ning J. Yue, Yin Zhang
Affiliation: Rutgers Cancer Institute of New Jersey, RWJBarnabas Health
Abstract Preview: Purpose: To investigate the potential impact of the Elekta Unity’s 1.5T magnetic field upon the performance of a conventional linac installed in an adjacent vault.
Methods: The linac vaults for thi...
Authors: Michael B. Altman, Zhuo Chen, Ella Lawrence, Borna Maraghechi, Ziad H. Saleh
Affiliation: Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: Structural shielding design for x-ray facilities, as specified in NCRP Report No. 151, is a detailed process but an important component of Medical Physics graduate and post-graduate education...
Authors: Hao Gao, Xue Hong, Harold Li, Yuting Lin, Jufri Setianegara, Xin Tong, Chao Wang, Weijie Zhang, Ya-Nan Zhu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high radiation doses to specific tumor regions (vertices) while sparing surroun...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Rami M. Shorti, Gary R. Stinnett
Affiliation: Intermountain Health, Radiation Oncology, Intermountain Health, Advanced Visualization Engineering Department
Abstract Preview: Purpose: In this work we present the workflow, materials analysis, and lessons learned from leveraging advanced 3D printing Polyjet Technology to print conformal bolus for radiation therapy.
Method...
Authors: Zhitao Dai
Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The Ohio State University James Cancer Hospital, The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: Accessibility is a topic of increasing importance in many fields, and medical physics is no exception. While the traditional educational pathway presents a plethora of challenges for the visu...
Authors: Rosa Maria Cibrián Ortiz de Anda, Altea C Esteve, Carlos M Galindo-González, Carmen C García, Amparo Gonzalez-Sanchis, Jose C Gordo-Partearroyo, Emilio Soria-Olivas, Javier Vijande
Affiliation: IFIC-UV, Valencia University, Hospital General Universitario
Abstract Preview: Purpose: To determine how skin microcirculation is affected by the two hypo-fractionated radiotherapy protocols in breast cancer patients using Laser Doppler Imaging, a non-invasive method for assessi...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose: In proton therapy, the substantial size of the gantry introduces sag, causing the proton isocenter to drift as a function of gantry angle. While the scanning magnets correct the beam’s isocen...
Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...
Authors: Wenwen Bai
Affiliation: The Fourth Hospital of Hebei Medical University
Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...
Authors: Jacinta E. Browne, Tzu Cheng Chao, Ajit Deveraj, Ece Ercan, Tim Leiner, Alessio Perazzolo, Michal Povazan, Jouke Smink, Camilla Vita, Spencer Waddle, Dinghui Wang
Affiliation: Università Cattolica del Sacro Cuore, Philips Healthcare, Mayo Clinic
Abstract Preview: Purpose:
In recent years, mid-field MRI has shown promise to meet the technical demands of cardiac imaging1. Mid-field strengths offer advantages to CMR due to shorter T1-relaxation times, lower sp...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis, Hamlet Spears
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the range of motion of abdominal organs using 4D stack-of-stars magnetic resonance (MR) imaging and 4D computed tomography (CT), the current clinical standard. Accurate o...
Authors: Brett Bocian, Patrick James Jensen, Luis Augusto Perles, Christopher J. Tien
Affiliation: Yale University School of Medicine, University of Miami, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Guidelines for dose prescriptions in endometrial cancer are based upon depth from the cylinder, traditionally 5 mm or 0 mm (i.e., surface). There are no current single-channel vaginal cylinde...
Authors: Laura A. Doyle, Amy S. Harrison, Allyson P Koecher, Jackson D Reeves, Lindsay B Romak
Affiliation: Christiana Care
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) is increasingly utilized in radiation oncology, allowing for transition away from permanent skin marks to SGRT-based daily treatment setup. Following i...
Authors: Jean Dessureault, Malcolm R. McEwen, Bryan R. Muir, James Renaud
Affiliation: National Research Council
Abstract Preview: Purpose: To develop and commission a mailable calorimeter that enables clinical medical physicists to quickly and efficiently address innovative dosimetry challenges directly at the point of use.
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Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...
Authors: Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose:
This study, the second in a two-part series, evaluates the isocenter position (the point in 3D space minimizing the sum of Euclidean distances to the MLC's central axis) and isocenter size...
Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...
Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...
Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...
Authors: Jordan B Lunsford, Sagar Pokhrel, Ashkan Shafiee, Curtis S. Whiddon
Affiliation: Atrium Health Wake Forest Baptist, University of North Carolina, Atrium Health Wake Forest Baptist High Point Medical Center
Abstract Preview: Purpose: To investigate the dosimetric characteristics of a platinum cured silicone rubber material (Platsil) for use as custom bolus in radiotherapy
Methods: Sheets of 2, 4, 6, and 8 mm Platsil we...
Authors: Amar K. Basavatia, Sandeepan Ganguly, Lee C. Goddard, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To investigate the dosimetric impact of WGTG51-e Report 385, recently updated CoP for clinical electron beams. This study uses a chamber specific effective point of measurement (EPOM) shift t...
Authors: Nguyen Phuong Dang, Mason Hazlett, Lijun Ma, Yutaka Natsuaki, William T. Watkins, Zhengzheng Xu, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, Radiation Oncology, Keck School of Medicine of USC, RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: This is the first study reporting the beam dosimetric parameter cross-checks of Reflexion linac using different water phantom systems and detectors. The difference in measurements using diffe...
Authors: Matthew Stephen Andriotty, Chi Ma, Xiao Wang, Keying (Karen) Xu, Suhong Yu, Ning J. Yue, Yin Zhang
Affiliation: Brigham and Women's Hospital, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To evaluate the effects of overlapping CT reconstruction on dosimetry calculation for LINAC-based SRS patients simulated on CT simulators from three different vendors.
Methods: CT simulati...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous, Roman Vasyltsiv, Rongxiao Zhang
Affiliation: Dartmouth Health, Dartmouth College, Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, University of Missouri
Abstract Preview: Purpose: On-patient dosimeters assist in clinical decision-making by measuring surface dose, but single-point measurements cannot monitor area-wide distributions and are misleading in high-gradient re...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Jing Feng, Wenzheng Feng, Joseph Hanley, Jeff Stainsby, Tingyu Wang
Affiliation: Synaptive Medical, Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose:
The Synaptive MRI is a 0.5T superconducting head only system (first US install 2023). This is the first study that evaluates the geometric accuracy using a Sun Nuclear MR Distortion and Im...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXion® X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...
Authors: Jihun Kim, Jin Sung Kim, Jun Won Kim, Yong Tae Kim, Chanwoong Lee, Jihyn Pyo, Young Hun Yoon
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Although segmentation foundation models have recently demonstrated promising zero-shot performance on natural images, its clinical application to magnetic resonance (MR) images still requires...
Authors: Yoonha Eo
Affiliation: Yonsei University
Abstract Preview: Purpose: To develop a fully automatic and unsupervised algorithm for estimating the Exposure Index (EI) of various Regions of Interest in X-ray imaging using advanced foundation models. Traditional EI...
Authors: Ashley Cetnar, Emily Y. Hirata, Cassandra Stambaugh
Affiliation: University of California San Francisco, Tufts Medical Center, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: To provide results from the first four years of the Medical Physics Leadership Academy (MPLA) Fundamental of Leadership Cohort program
Methods: The MPLA Cohorts program began with the Fund...
Authors: Ning Cao, Sunan Cui, Danielle P. Johnson Erickson, Juergen Meyer, Ramesh Rengan, Ben A Shaver, Jing Zeng
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To investigate the immune response in primary irradiated tumors and non-irradiated tumors in a mouse melanoma xenograft model, comparing 18Gy of conventional (CONV) and ultra-high dose rate (...
Authors: Caroline Esposito, Keith T Griffin, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock
Affiliation: East Carolina University, University of Michigan, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: The National Cancer Institute’s Pediatric Proton and Photon Therapy Comparison Cohort aims to collect and analyze data from cancer centers across the United States and Canada to quantify diff...
Authors: Youssef Ben Bouchta, Chen Cheng, Owen Thomas Dillon, Mark Gardner, Paul J. Keall, Purnima Sundaresan
Affiliation: Radiation Oncology Network, Western Sydney Local Health District, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: There are three clinical motivations for real time IGRT in head and neck cancer radiation therapy: (1)50% of patients experience anxiety from the patient mask (2)patient motion still occurs d...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...
Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...
Authors: Ryan Gentzler, Xin He, James Larner, J.T. Morgan, Cam Nguyen, Wendy Stewart, Krishni Wijesooriya, Grant Williams
Affiliation: Department of Physics, University of Virginia, Department of Radiation Oncology, University of Virginia, Division of Hematology & Oncology, Department of Medicine, University of Virginia
Abstract Preview: Purpose: Some recent studies have shown Overall Survival (OS) of advanced-stage lung cancer patients treated with chemo-radiation therapy (CRT) is correlated with heart dose [1-5], while in other stud...
Authors: Wamied T. Abdel-Rahman, Iqbal AlAmri, Lma Alahmare, Ghada Aldosary, Marwa Alghamdi, Lujain Aljadou, Yarah Alkhulaif, Abdullah A. Alshreef, Ohoud Alsubaie, Hoton Alsufyani
Affiliation: Loma Linda University Medical Center, Princess Nourah Bint Abdulrahman University, King Fahad Specialist Hospital, KAMC- Ministry of National Guard Health Affairs, SQCCCRC, KASCH- Ministry of National Guard Health Affairs
Abstract Preview: Purpose: The shortage of qualified medical physicists in many developing countries is due to multiple factors such as lack of awareness or access to graduate and residency training programs. An outrea...
Authors: Abdullah A. Alshreef, Elizabeth L. Bossart, Ashley Cetnar, Leonard H. Kim, Neil A. Kirby, Anna E. Rodrigues, Xin Wang, You Zhang
Affiliation: University of Miami, The University of Texas MD Anderson Cancer Center, Loma Linda University Medical Center, MD Anderson Cancer Center at Cooper, Cooper Medical School of Rowan University, The Ohio State University - James Cancer Hospital, UT Health San Antonio, Duke University, 5940 forest park road
Abstract Preview: Purpose: AAPM TG-298 reported several concerns regarding the training and education of alternative pathway candidates. Medical physics postdoctoral research, though not part of the certification pathw...
Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich
Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...
Authors: MacKenzie Rachelle Coon, Justin Geise, Judith Noemi Rivera, Matthew L. Scarpelli, Jessica Leigh Veenstra, Chandler Zaugg
Affiliation: Purdue University, Indiana University
Abstract Preview: Purpose: Glioblastoma (GBM) is among the most aggressive and treatment-resistant cancers due to its immunosuppressive tumor microenvironment. Immunotherapy holds promise for GBM treatment, but its eff...
Authors: Mandar S. Bhagwat, Casey Y. Lee
Affiliation: Duke University, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: TG43-based dose calculation leads to inaccurate field-size dependent dose calculation in superficial HDR brachytherapy, due to full-scatter condition accounted in TG43, but not during treatme...
Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie
Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine
Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...
Authors: Peng Dong, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Stanford University
Abstract Preview: Purpose: Volumetric Modulated Arc Therapy (VMAT) optimization is a complex, non-convex problem with numerous variables and intricate constraints. Traditional optimization methods often lack efficiency...
Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar
Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University
Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...
Authors: Palanisamy Karunanithi, Karthikeyan Perumal, Siva Subramanian Vadivel
Affiliation: Dr. Kamakshi Memorial Hospital
Abstract Preview: Purpose:
Recent advancements in high dose-rate (HDR) brachytherapy include the image guidance, new applicators, and dose calculation algorithms. Brachytherapy has steep dose gradient, hence relativ...
Authors: Simona Cacciatore, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Julien Smeets, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To evaluate time reduction strategies for the Dynamic Collimation System (DCS) using an IBA (Louvain-la-Neuve, Belgium) proton therapy system. Delivery time for a multi-energy-layer patient s...
Authors: Mark W. Geurts, Bridget Ann Melke
Affiliation: Aspirus Health
Abstract Preview: Purpose:
To develop a tool that streamlines and standardizes the process of positioning the SRS MapCHECK detector for intersecting multiple metastases during SRS QA of Single-Isocenter, Multiple Ta...
Authors: Charles D. Bloch, Stephen R. Bowen, Bing-Hao Chiang, Alex Egan, Eric C. Ford, Sharareh Koufigar, Dominic A. Maes, Juergen Meyer, Sharon Pai, Frank Rafie, Rajesh Regmi, Jatinder Saini, George A. Sandison, Marco Schwarz, Bishwambhar Sengupta, Tony P. Wong
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington
Abstract Preview: Purpose: This study aimed to optimize the strategy and timing of physics consults for proton prostate patients to improve the patient experience and resource utilization in our radiation oncology depa...
Authors: Shifeng Chen, Erica Fisler, Arun Gopal, Mariana Guerrero, Jason Hendershot, Kai Huang, Eric Kusmaul, Adam Schrum, Megan Steinberg, Kai Wang
Affiliation: University of Maryland School of Medicine, Department Radiation Oncology, Kaufman Cancer Center, Upper Chesapeake Medical Center, University of Maryland Medical System Central Maryland Radiation Oncology, Department of Radiation Oncology, University of Maryland Medical Center, Baltimore Washington Medical Center Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
Our goal is to develop and clinically deploy an automated planning tool using multicriteria optimization (MCO) for VMAT in prostate only, whole pelvis radiotherapy treatments.
Methods:<...
Authors: Marwan Belal AbuHaija, Anis Ahmad, Chase Prescott Anderson, Nesrin Dogan, John C. Ford, Alan Pollack, Junwei Shi, Jorge D Vega, Gabriel Enrique de Hostos
Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Raman Spectroscopy (RS) is a non-invasive, label free imaging modality that gathers intrinsic molecular vibrational information. Portable RS systems expand affordability and convenience, supp...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Julien Bancheri, Chau Giang Bui, David G Cooke, Christopher M Lund, Morgan J Maher, Jan P. Seuntjens, Jason Z Yuan
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Medical Biophysics, University of Toronto, University of Toronto, Medical Physics Unit, McGill University, Department of Physics, McGill University
Abstract Preview: Purpose: The dielectric wall accelerator (DWA) offers a low-cost solution for proton therapy, using non-resonant waveguides to accelerate particles. Radial waveguides (RWGs), consisting of a dielectri...
Authors: Alexandru Badalan, Peter Petric, I. Antoniu Popescu, Andrew Kyle Henderson Robertson
Affiliation: Bc Cancer, BC Cancer - Vancouver, BC Cancer
Abstract Preview: Purpose: Ultra-high dose rate (>40 Gy/s) or “FLASH” radiation therapy (RT) has the potential to improve cancer treatment through reduced radiation side effects. While electron FLASH beams can be produ...
Authors: Tianliang Gu
Affiliation: UT Health Science Center at Houston
Abstract Preview: Purpose:
In Nuclear Regulatory Commission guide 8.39 on releasing patients administered radioactive material, the dose is calculated assuming both the source and receiver are points. This point mod...
Authors: Rajeev K. Badkul, Ronald C Chen, Ying Hou, Harold Li, Chaoqiong Ma, Jufri Setianegara
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose:
Postimplant urinary toxicity is common in prostate low-dose-rate (LDR) brachytherapy. We developed a machine learning (ML) model to explore the correlation between spatial dose distributio...
Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone, Lesley A Jarvis, Allison Matous
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: During external beam radiation therapy, couch kicks are often necessary to achieve effective treatments, yet they make interpreting Cherenkov images much more challenging. We present a surfac...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....
Authors: Xiangli Cui, Wanli Huo, Jie Li, Lingling Liu, Tao Ma, Yuanyuan Wang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Ion Medical Center, Hefei Cancer Hospital, Chinese Academy of Sciences, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University
Abstract Preview: Purpose: In practice, treatment planning systems (TPS) of proton therapy require a CT calibration curve, which relates Hounsfield units (HU) to relative stopping power (RSP). Single-energy CT as a sta...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Ana Maria Barragan Montero, John A. Lee, Eliot Peeters, Romain Schyns, Edmond S. Sterpin, Sophie Wuyckens
Affiliation: UCLouvain, Universite Catholique de Louvain
Abstract Preview: Purpose:
Although the likelihood of a point being tumorous decreases with distance from the GTV, CTVs are still defined as binary masks. Recently, the concept of clinical target distribution (CTD),...
Authors: Jiayun Chen, Shengqi Chen, Junchao Li, Fei Liu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Tongji Medical College, Huazhong University of Science & Technology, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To assess if 3D Vane MRI can accurately depict the motion of the target volume and OARs.
Methods: This retrospective study included 54 liver cancer patients who underwent both 3D Vane MRI ...
Authors: Andrew Groll, Ayan Mitra, PhD, Manoj Narayanan, Sanchit Sharma, Ray Yang, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: To develop a versatile QA tool enabling dose recalculation of a patient’s plan sinogram redeployed onto arbitrary replacement phantom geometry, and extract computed dose along detector planes...
Authors: Jie Hu, Nan Li, Chuanbin Xie, Shouping Xu, Xinlei Xu, Gaolong Zhang, Zhilei Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, the First Medical Center of the People's Liberation Army General Hospital, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology, School of Physics, Beihang University, Beijing, 102206, Peopleʼs Republic of China
Abstract Preview: Purpose: This study aims to synthesize CT images for MRI-only radiation therapy using a deep learning approach that integrates information from the T1- and T2-weighted MRI sequence.
Methods: 97 hea...
Authors: John P. Aris, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Ann M. Chan, Chansoo Choi, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier
Affiliation: University of Florida
Abstract Preview: Purpose: In preclinical studies, minipigs serve as valuable experimental models for predicting absorbed doses due to their anatomical and physiological similarities to humans. However, minipig computa...