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Results for "oxidative stress": 2 found

In Vivo Measurements of Hydrated Electron Production with an Ultra-High Dose Rate (UHDR) Electron Beam

Authors: Xu Cao, Wesley S. Culberson, Aubrey Parks, Brian W Pogue, William Scott Thomas

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison

Abstract Preview: Purpose:
The hydrated electron is a critical reactive species generated during the radiolysis of water when ionizing radiation interacts with biological tissues. It plays a pivotal role in mediatin...

Inhibition of Metabolism Radiosensitizes Lung Cancer Cells to Photons and Protons

Authors: Scott James Bright, Hadil Elldakli, Mojtaba Hoseini-Ghahfarokhi, Rishab Kolachina, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Gabriel O. Sawakuchi, Walison Augusto Silva Brito, Mark Wasley

Affiliation: MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center, Medical College of Georgia

Abstract Preview: Purpose:
Glutaminase 1 (GLS1) is an intracellular enzyme crucial for generating antioxidants such as glutathione (GSH). GSH neutralizes reactive oxygen species (ROS) induced by radiotherapy. About ...