Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Chuan He, Anh H. Le, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, Cedars-Sinai
Abstract Preview: Purpose: To develop a non-measured and DVH-based (NMDB) IMRT QA framework integrating machine learning (ML) to classify lung SBRT VMAT plans prone to delivery errors
Methods: 560 Eclipse AcurosXB l...
Authors: Ivan L. Cordrey, Dharmin D. Desai
Affiliation: Cumberland Medical Center - Cancer Center, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: For larger PTVs, VMAT optimizations performed within Eclipse often generate SRS plans with widely scattered hotspots distributed around the inner edge of the PTV – the “ring of fire.” This pr...
Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...
Authors: John Bennet, Indrin J. Chetty, Tai H. Dou
Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center
Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...
Authors: Zhitao Dai
Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...
Authors: Shahed Badiyan, Tsuicheng D. Chiu, Viktor M. Iakovenko, Steve Jiang, Christopher Kabat, Mu-Han Lin, Roberto Pellegrini, Arnold Pompos, Edoardo Salmeri, David Sher, Sruthi Sivabhaskar, Justin D. Visak
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Global Clinical Science, Elekta AB, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Adaptive treatment planning requires robust strategies to enable streamlined on-couch processes, creating a significant barrier for planners transitioning from conventional to adaptive planni...
Authors: Hongyu Jiang, Wangyao Li, Dima Soultan, Fen Wang, Jun Xu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: To validate the Auto-Beam Hold functionality via the MMI connection between Varian SGRT system IDENTIFY 3.0 and treatment linacs.
Methods: A treatment plan was created in the Eclipse TPS u...
Authors: Ryan Clark, Anthony Magliari, Luis Felipe Oliveira E Silva, Yang Sheng, Jason R Vickress, Qingrong Jackie Wu, Giulianne Rivelli Rodrigues Zaratim
Affiliation: Verspeeten Family Cancer Center, Office of Medical Affairs, Varian, A Siemens Healthineers Company, Confiar Radioterapia, Duke University Medical Center
Abstract Preview: Purpose: Develop a toolset to replace several of the tedious steps required to manually generate 3D breast treatment plans using static gantry forward planned tangent beams.
Methods: Eclipse Sc...
Authors: Martha J. Malin, Matthew Schelin
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.
Authors: Clifford Ghee Ann Chua, Calvin Wei Yang Koh, Kah Seng Lew, Zubin Master, Sung Yong Park, Hong Qi Tan, Andrew Wibawa
Affiliation: National Cancer Centre Singapore
Abstract Preview: Purpose: To investigate the impact of spot position deviation on reference dosimetry measurements using different delivery patterns and to determine the optimal delivery pattern for reference dosimetr...
Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patient’s nose relative to two stationary reflectors on th...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao
Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...
Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Michael Leyva, Alejandro Rene Llanes Lopez, William Romaguera, Ranjini P. Tolakanahalli, Deborah Wang
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose: To evaluate whether a modulated electron bolus (MEB) technique improves both nominal and shifted dose distributions in nasal electron therapy as compared to a non‑modulated, uniform‑thickness...
Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre
Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey
Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...
Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...
Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy
Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics
Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...
Authors: Stella Flampouri, Edgar Gelover, William Andrew LePain, Roelf L. Slopsema, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University
Abstract Preview: Purpose: Little consideration was given to the change in dose rate (DR) observed when moving to pencil beam scanning (PBS). This study reports on DR in clinical prostate PBS plans. While dose distribu...
Authors: Chia-Lung Chien, Wen C. Hsi, Romy Megahed, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
The dosimetric variations induced by inter-fractional anatomical changes in intensity-modulated proton therapy could impact the clinic outcomes for head-and-neck (HN) cancer patients. This...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXion® X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
Treatment planning for intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) relies on inverse planning, an iterative and non-intuitive process of adjust...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Kenneth L. Homann, Natalie A Lockney, Hong Zhang
Affiliation: Department of Radiation Oncology, Vanderbilt University Medical Center, Vanderbilt University Medical Center
Abstract Preview: Purpose: The aim of this study is to develop a treatment planning methodology utilizing liver functional imaging via contrast-enhanced Magnetic Resonance Imaging (MRI) in patients undergoing stereotac...
Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu
Affiliation: Willis Knighton Cancer Center
Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...
Authors: Shen Fu, Jun Hou, Zuofeng LI, Taize Yuan, Qingyuan Zhang, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center, 广州泰和肿瘤医院
Abstract Preview: Purpose: A visual feedback system is beneficial for patients to maintain consistent respiratory signal during gated radiotherapy, especially for intensity modulated proton therapy (IMPT) where motion ...
Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...
Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University
Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...
Authors: Ahmet S. Ayan, Estelle Batin, Austin M. Faught, Peter E. Klages, Eunsin Lee, Collin Nappi, Mina Okello, Meghana Ramani, Zachary X. Richards, Parisa Sadeghi
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University
Abstract Preview: Purpose: Neutron doses are not modelled in proton treatment planning systems, so measurements were taken with two independent dosimeter types to quantify representative neutron fetal doses in pencil b...
Authors: Jon Burns, Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy uses positron emissions from FDG-avid tumor volumes to provide a of the planned prescribed dose with high accuracy. The purpose of this work is to characterize BgR...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: D. Michael Lovelock, Charlotte Elizabeth Read, Ren-Dih Sheu, Jing Wang, Tingyu Wang
Affiliation: Icahn School of Medicine at Mount Sinai, Jersey Shore University Medical Center
Abstract Preview: Purpose:
Early Eclipse models use rectangular fluence profiles (widened by the dosimetric leaf gap (DLG) to account for the fact that leaf tips are rounded). Eclipse Version 18 (V18) uses enhanced ...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose:
This study evaluates optimization strategies in the Gamma Knife Gamma Plan Lightning optimizer for simultaneous integrated boost (SIB) scenarios, aiming to identify clinically viable setti...
Authors: Daniel A. Alexander, Jonathan Baron, Brook Kennedy Byrd, William Ross Green, Bolin Li, Rafe A. McBeth, Abigail Pepin, Steven Philbrook
Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, Thayer School of Engineering, University of Pennsylvania
Abstract Preview: Purpose: As accelerated partial breast irradiation (APBI) gains traction, the prospect of a rapid sim-to-completion of treatment workflow is an attractive option for patients. While OAR autocontouring...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Frameless gamma knife (GK) treatments use a thermoplastic mask coupled with high-definition motion management system that utilizes an infrared camera, and a reflective marker placed on the pa...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Kevin Peter Risolo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: To quantify the improved efficiency of checking patient treatment plan MU by utilizing RadFormation’s ClearCalc script-based program.
Methods: A total of 58 patients planned for treatment ...
Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.
Methods: A commercial rotational table (CDR Equilibrium®) is r...