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Results for "power ratio": 56 found

A Comparative Study of Hypersight and Truebeam Cone Beam Computed Tomography Image Quality

Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao

Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah

Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...

A Novel 2D Scintillation Dosimeter Using Long Scintillating Fibers.

Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan

Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval

Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...

A Novel Proton Lattice Modality Using Minibeams

Authors: Hao Gao, Yuting Lin, Nimita Shinde, Weijie Zhang

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: LATTICE, a form of spatially fractionated radiation therapy (SFRT), delivers high-dose peaks and low-dose valleys to the target volume and has been clinically used for large target volumes. H...

A Robust Quantitative Metric for Optimal Beam Selection in Radiotherapy of the Peripheral Lung Lesions: A Crucial Step in Standardization of Lung SBRT

Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...

A Simplified, Rigorous Procedure for Ultrasound Quality Assurance

Authors: Paul L. Carson, Sander Dekker, Stephen Z Pinter, Megan K. Russ

Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Michigan, Cablon Medical B.V., Univ of Michigan, Dept. of Radiology

Abstract Preview: Purpose:
To promote a simplified, inexpensive, but rigorous set of ultrasound QA tests and to evaluate their potential using a Randomly-placed very Hypoechoic Sphere Phantom (RHSP) in comparison to...

Absolute Measurement of HDR Ir-192 Air-Kerma Strength Using an Exradin A3 Known-Volume Ionization Chamber

Authors: Larry A. DeWerd, Sean Jollota, Karen Rex Pius Vincent

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: Absolute measurements, often used to establish primary standards, offer lower measurement uncertainty. For 192Ir high-dose-rate (HDR) brachytherapy, the interim primary standard for air-kerma...

Accelerated Proton Density Imaging Via T2-Guided Cyclegan Super-Resolution without Paired Low-Resolution and High-Resolution Data

Authors: Yunxiang Li, Xinlong Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Acquiring high-resolution (HR) proton density (PD) images is time-consuming, while lower-resolution (LR) PD scans are faster but can lack sufficient details. We propose CycleHR, a T2-contrast...

An Evaluation of an SRS Quality Assurance System for Complex Patient Plans.

Authors: John Bennet, Indrin J. Chetty, Tai H. Dou

Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center

Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...

An Initial Simulation Study Towards the Patient-Specific Estimation of Stopping Power Ratio and Sound Velocity Using Protoacoustics: A Sensitivity Matrix Method

Authors: Ye Chen, Koki Kasamatsu, Taeko Matsuura, Taichi Murakami

Affiliation: Hokkaido University, National Institutes for Quantum Science and Technology (QST)

Abstract Preview: Purpose: In proton therapy, CT-based estimation of the stopping power ratio (SPR) is a significant source of range uncertainty. Protoacoustics have been developed to estimate the range in vivo, but fe...

Analytical Approach to Calculate Normal Tissue Complication Probability and Tumor Control Probability for Ultra-High Dose Rate Radiation (FLASH) Based on Linear-Quadratic Model

Authors: Santosh K. Agarwalla, Nrusingh C. Biswal, Shree C, Harikrishnan Suresh Kumar, Jajati K. Nayak, Prema P., Sarath K S, Tamil Selvan S, Hem D. Shukla

Affiliation: Variable Energy Cyclotron Centre, Department of Physics, Fakir Mohan University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Sciences, Amrita Vishwa Vidyapeetham

Abstract Preview: Purpose: The rapid oxygen depletion in tissues during irradiation is the most accepted mechanism of the FLASH effect. However, the Normal Tissue Complication Probability (NTCP) and Tumor Control Proba...

Can Contrast Scans of Dual-Layer Detector Spectral CT be Directly Used for Proton Dose Calculations?

Authors: Wen C. Hsi, Pouya Sabouri, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
Traditional single-energy CT (SECT) contrast scans cannot be used for proton dose calculations due to significantly higher HU caused by iodine. Dual-layer dual-energy CT (DL-DECT) can dire...

Characterizing the Stability of Upright CT for Proton Therapy

Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan

Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care

Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...

Comparing SPECT Dose Reconstruction Algorithm Accuracy As a Function of Imaging Parameters

Authors: Srinivas Cheenu Kappadath, Brian Michael Kelley, Benjamin P. Lopez

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Imaging systems are subject to errors from finite spatial resolution and voxel size. This work demonstrates their effect on dose algorithm {Monte Carlo (MC), dose-volume kernel (DVK), and ...

Denoising Diffusion-Weighted Images of Rectal Cancer Acquired on a 0.35 T Magnetic Resonance Imaging-Guided Linear Accelerator Using Singular Value Decomposition

Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...

Design of Filtimator (Filter + Collimator) for CBCT of Pediatric Cancer Patients Receiving Proton Therapy

Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens

Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI

Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) doses shall be limited for pediatric patients in clinical settings. Device called Filtimator (filter+collimator) was custom designed to reduce setup CB...

Detector Physics-Incorporated Diffusion Denoising Models for Digital Breast Tomosynthesis with Dual-Layer Flat Panel Detectors

Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao

Affiliation: Stony Brook Medicine, Massachusetts General Hospital

Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...

Determination of HU Override for Small Metal Implants in Proton Therapy

Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang

Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale

Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...

Developing a Dataset for Investigations into the Impact of CT Acquisition and Reconstruction Conditions on Quantitative Imaging Using Paired Image Quality and Radiomics Phantom Data

Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese

Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory

Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...

Dose Distribution Analysis for Different Geometries of a Multiple-X-Ray Source Array (MXA) CT Scanner

Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou

Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation

Abstract Preview: Purpose: A Multiple-X-ray Source Array (MXA) for CT (MXA-CT) is under development to mitigate cone beam artifacts in axial CT scans using wide collimation. The purpose of this study is to assess the i...

Dosimetric Comparison & Error Analysis of Aapm TG51 & WGTG51-e Protocol with Icru-90 Key-Data for High-Energy Clinical Electron Beam

Authors: Amar K. Basavatia, Sandeepan Ganguly, Lee C. Goddard, Wolfgang A. Tomé

Affiliation: Montefiore Medical Center

Abstract Preview: Purpose: To investigate the dosimetric impact of WGTG51-e Report 385, recently updated CoP for clinical electron beams. This study uses a chamber specific effective point of measurement (EPOM) shift t...

Energy Dependency of Biological Effects from Radiation Scattering Around Medical Implants in Particle Therapy

Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum

Affiliation: Osaka University, Texas A&M University

Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...

Enhancing T2-Weighted Brain MRI Resolution across Orientations Using AI-Based Volumetric Reconstruction

Authors: Mengqi Shen, Meghna Trivedi, Tony J.C. Wang, Andy (Yuanguang) Xu, Yading Yuan

Affiliation: Columbia University Medical Center, Dept of Med Hematology & Oncology, Data Science Institute at Columbia University, Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center

Abstract Preview: Purpose: T2-weighted (T2w) images are critical for identifying pathological changes due to their superior contrast in differentiating tissue types. However, they often lack detailed anatomical resolut...

Explaining the Normal Tissue Sparing of Flash By Oxygen Fixation Hypothesis

Authors: Daisuke Kawahara, Yoichi Watanabe

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School

Abstract Preview: Purpose: To theoretically demonstrate that FLASH dose delivery leads to higher normal tissue sparing than conventional dose rates.
Methods: A two-component kinetic model was built for target and da...

Feasibility of Rapidarc Dynamic for Lattice Radiation Therapy of Bulky Liver Tumors

Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles

Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...

Feasibility of a Normoxic N-Vinylpyrrolidone-Based Polymer Gel (VIPET) Dosimeter for Three-Dimensional Proton Beam Measurements

Authors: Yoshihiko Hoshino, Kenji Hotta, Taeko Matsuura, Ai Nakaoka, Hidenobu Tachibana

Affiliation: Hokkaido University, Department of Radiology, Gunma University Hospital, Radiation Safety and Quality Assurance Division, National Cancer Center Hospital East

Abstract Preview: Purpose: Gel dosimeters enable three-dimensional dose measurements, but no reports have evaluated the fundamental performance of VIPER-type gel dosimeters in proton beam measurements. Therefore, we ev...

Generalizable 7T T1 Map Synthesis from 1.5T and 3T T1W MRI for High-Resolution MRI-Guided Radiation Therapy

Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu

Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine

Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...

Generation of Patient-Specific Phantom for Head & Neck Proton Therapy Based on Xcat

Authors: Cheng-En Hsieh, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu, An-Ci Yang

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose:
The aim of this study is to develop a framework of generating patient-specific phantom tailored for head and neck proton therapy. From these phantoms, digital reference objects based on th...

Getting in Focus: Review of Current Focal Spot Size Testing Methods with Flat Panel Digital Radiography Detectors

Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda

Affiliation: Yale University School of Medicine, Yale University

Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...

Glandular Dose Map in Voxelized Phantoms across Advanced Breast Imaging Modalities Obtained from Monte Carlo Simulations

Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin

Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven

Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...

HyperArcTM Automated Radiosurgery Planning Enables Accurate a Priori Isotoxic Prescription Dose Selection

Authors: Rex A. Cardan, Carlos E. Cardenas, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li, Rodney J. Sullivan, Natalie N. Viscariello, Christopher Willey

Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: vBrain radiosurgery toxicity-rate is estimated via clinically-relevant isodose volume (IDV) thresholds according to HyTEC (e.g., V12Gy≤10cc). HyperArcTM (HA) automated planning allows accurat...

Image Quality Improvement Using a Patient-Specific Post-Trigger Delay Protocol for Coronary CT Angiography

Authors: Cecelia Brewington, Connor Edwards Miles All Leska-Kent, Kyrillos Grace, Katherine Hyde, Sabee Molloi, Shiva Mostafavi, Liqiang Ren, Alireza Shojazadeh, Justin Truong

Affiliation: Department of Radiology, UT Southwestern Medical Center, University of California, Irvine, University of Texas Southwestern

Abstract Preview: Purpose: To retrospectively assess image quality in coronary CT angiography (CCTA) using a patient-specific post-trigger delay (PTD) protocol, developed using half of the injection time plus a dispers...

Imaging Performance of Direct-Indirect Dual-Layer Flat-Panel-Detector Prototypes for Contrast-Enhanced Digital Mammography

Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc Laperrière, Xiangyi Wu, Wei Zhao

Affiliation: Stony Brook Medicine, Analogic Canada

Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...

Impact of Diacetylene Polymer Chemistry on Real-Time Radiochromic Film Dosimetry

Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink

Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University

Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...

Inhibition of Metabolism Radiosensitizes Lung Cancer Cells to Photons and Protons

Authors: Scott James Bright, Hadil Elldakli, Mojtaba Hoseini-Ghahfarokhi, Rishab Kolachina, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Gabriel O. Sawakuchi, Walison Augusto Silva Brito, Mark Wasley

Affiliation: MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center, Medical College of Georgia

Abstract Preview: Purpose:
Glutaminase 1 (GLS1) is an intracellular enzyme crucial for generating antioxidants such as glutathione (GSH). GSH neutralizes reactive oxygen species (ROS) induced by radiotherapy. About ...

Inter-Patient Registration Methods for Voxel-Based Analysis in Lung Cancer

Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...

Investigation of Flash Proton Irradiation Induced DNA Double Strand Breaks Under Different Free Radical Scavenger Environments

Authors: Hansong Bai, Peter Jermain, Xun Jia, Heng Li, Devin Miles, Daniel Sforza, Michael H. Shang, Daniel Robert Strauss, Keith Unger, Lingshu Yin

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, MedStar Georgetown University Hospital, Johns Hopkins University, Department of Radiation Medicine, MedStar Georgetown University Hospital

Abstract Preview: Purpose: To investigate DNA Double Strand Break (DSB) induced by FLASH proton irradiation in a repair-free plasmid DNA model under different free radical scavenging conditions in plateau and Bragg pea...

Ir-192 Percentage Depth Ionization of PLA and Ballistic Gelatin Compared to Water

Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Ching-Ling Teng, Nadia M. Vassell

Affiliation: Northwell, Mount Sinai Beth Israel

Abstract Preview: Purpose:
The flexible nature of ballistic gelatin and 3D printed material such as PLA lend themselves to phantom studies in brachytherapy. While these materials can allow for easy simulation of cat...

Moving Towards Independent Assays of 90y Glass Microsphere Activity: Monte Carlo Simulation with Experimental Data

Authors: Mercy Iyabode Akerele, Yuni K. Dewaraja, Richard Laforest, Justin K. Mikell, Wendy Siman, Allan Thomas, Daniel Thorek

Affiliation: University of Michigan, Washington University School of Medicine in St. Louis, Washington University School of Medicine, University of Colorado Anschutz Medical Campus, School of Medicine, Washington University in St. Louis, Mallinckrodt Institute of Radiology, Washington University School of Medicine

Abstract Preview: Purpose: Post-therapy quantitative 90Y SPECT and PET measurements show ~25% lower activity than vendor-reported values for glass microspheres. We hypothesize this discrepancy is due to bremsstrahlung ...

Nausea, Heartburn, K-Edge Imaging: Pepto Bismol As a CT Contrast Agent

Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson

Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital

Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...

Non-Invasive Photoacoustic Thermometry for Real-Time Monitoring of Tissue Temperature Using Frequency Analysis

Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar

Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University

Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...

Ocular HDR Brachytherapy End-to-End Dose Verification with Iridum-192 Calibrated Oslds

Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Nadia M. Vassell

Affiliation: Mount Sinai Beth Israel

Abstract Preview: Purpose: Ocular HDR brachytherapy is used as an alternative treatment for eye cancer, especially with extrascleral extension in the orbit. This complex procedure inserts catheters into the orbit affix...

On Dosimetric Water Equivalency of 3D Printed Materials

Authors: Emily Helen Hayes, Luke Maloney

Affiliation: University of Florida

Abstract Preview: Purpose: To determine the dosimetric water equivalency of polylactic acid (PLA) and commercial 3D printing resin using electron stopping power as a surrogate, for use in radiochromic film calibration ...

Predicting Prostate Cancer Recurrence Using an Atlas-Based Tumor Control Probability Model

Authors: Jeremy T. Booth, Martin Andrew Ebert, Robert Finnegan, Annette Haworth, George Hruby, Burhan Javed, Kazi Ridita Mahtaba, Leyla Moghaddasi, Yutong Zhao

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, The University of Sydney, The University of Western Australia, Genesis Care, Rockhampton Hospital

Abstract Preview: Purpose:
To evaluate the efficacy of an atlas-based tumor control probability (TCP) model in predicting prostate cancer (PCa) recurrence by retrospectively integrating patient-specific primary radi...

Predicting Proton Therapy Dose Delivery Accuracy: A Machine Learning Approach Using Iroc’s Proton Phantom Data

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROC’s proton phantom program.
Methods: IROC’s proton QA program has six proton...

Predictive Quality of Differing Body Size Measurands for Radiation Risk Estimation in CT Imaging: A Virtual Trial Study

Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells

Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...

Quantifying Respiratory Motion Effects in Lung Cancer Radiotherapy Using 4DCT Voxel Analysis

Authors: Chih-Chiang Chang, Chingyun Cheng, Ben Durkee, Minglei Kang, Elissa Khoudary, Yangguang Ma, Xuanqin Mou, YuFei Wang, Tengda Zhang, Wang Zhengda

Affiliation: Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Medical Physics, Columbia University, University of Pennsylvania, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: This study presents a voxel-based analysis method based on deformable image registration to accurately quantify respiratory-induced motion and deformation of both targets and organs at risk (...

Quantitative Analysis of Long-Term Optical Density Variations of Irradiated and Un-Irradiated EBT3 Films

Authors: Rick Holly, Sumudu Katugampola

Affiliation: Gesinger Medical Center, Geisinger Medical Center

Abstract Preview: Purpose:
To quantitatively analyze long term variations in optical density of un-irradiated and irradiated EBT3 radio-chromic films and their effects on dose calibration curves in a clinical settin...

Signal-to-Noise Ratio Estimation from Polynomial Fitting of Acr MRI Phantom Images

Authors: Alex Lindgren-Ruby, Jeffrey M. Moirano, Joseph Everett Wishart

Affiliation: University of Washington

Abstract Preview: Purpose:
To evaluate polynomial fitting of signal intensity for signal-to-noise ratio (SNR) estimation from weekly QC ACR MRI phantom images and compare against other SNR estimation methods as well...

Streamlining Quality Control for Radiographic and Fluoroscopic Systems

Authors: Caroline Cheney, Patricia G Collins, Allen R. Goode, Preston Le, Andrew M. Polemi, Angela Snyder

Affiliation: UVA Health, Atirix Medical Systems

Abstract Preview: Purpose: Optimize ongoing quality control (QC) for radiographic (DR) and fluoroscopic (FL) systems by identifying metrics most sensitive to hardware disruptions among regional noise, pooled noise, sig...

Synthetic Vs. Conventional Planar Imaging: Performance and Clinical Feasibility

Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman

Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University

Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...

Task Specific Image Quality Assessment Using Spectral Photon-Counting CT.

Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq

Affiliation: Khalifa University

Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...

Transforming CT Technologist Training: Real-Time Feedback, Gamification, and Phantom-Based Education for Accurate Patient Positioning

Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps

Affiliation: University of New Mexico Hospital

Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...

Universal Range Modulators for Flash Proton Therapy: 3D Printing of Stackable Variable Density Units

Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...

Using Contrast-Enhanced Computed Tomography for Non-Invasive Lung Shunt Fraction Prediction in Yttrium-90 Radioembolization

Authors: Roger Eric Goldman, Adrianna Imani Johnson Carter, Talia Marx, Brahim Mehadji, Emilie Roncali, Catherine T. Vu

Affiliation: UC Davis, Department of Radiology, UC Davis Health

Abstract Preview: Purpose:
Accurate estimation of the Lung Shunt Fraction (LSF) is critical for yttrium-90 (90Y) radioembolization treatment planning to minimize risks of excessive lung irradiation due to arterio-ve...

Validation of Updated CT-to-SPR Calibration Method with Icrp-145 Data for Carbon-Ion Radiotherapy

Authors: Min Cheol Han, Soorim Han, Chan Hyeong Kim, Jin Sung Kim, Seok-Ho Lee, Gahee Son, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: The stoichiometric calibration method proposed by Kanematsu et al. (2016) has been widely adopted for CT number to stopping-power ratio (SPR) conversion in carbon-ion radiotherapy. With the r...

Voxel-Dose Implications of Single-Compartment Dosimetry for Ablative 90Y-Radioembolization Segmentectomy

Authors: Srinivas Cheenu Kappadath, Benjamin P. Lopez, Armeen Mahvash

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose: 90Y-radioembolization is utilized with curative intent. While single-compartment doses to the perfused volume for the complete pathologic necrosis (CPN) of tumors have been reported, the actu...