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Results for "pre calibration": 22 found

A GUI-Based Python Platform for the Quantification of Pre-Clinical Planar Optical Imaging Using 3D Anatomical Information

Authors: Bryan Bednarz, Malick Bio Idrissou, Campbell Haasch, Reinier Hernandez

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, University of Wisconsin - Madison

Abstract Preview: Purpose: Quantitative optical imaging is a powerful tool in murine models for assessing tumor growth and metastatic spread using bioluminescence imaging (BLI) and for detecting radiopharmaceutical upt...

A Novel Margin-Based Focal Distance Loss for Lesion Segmentation in Medical Imaging

Authors: Weiguo Lu, Hua-Chieh Shao, Guoping Xu, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Neural network-based lesion segmentation remains a significant challenge due to the low contrast between lesions and surrounding tissues (high ambiguity) and the variability of lesion shap...

Characterization and Validation of Cerenkov Radiation Extraction Methods from a Plastic Scintillation Detector in 0.35T MR-Linac Environments

Authors: Mateb Ali Alghamwa, Haya Aljuaid, Siyong Kim, Tianjun Ma, William Song

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: The integration of Plastic Scintillation Detectors (PSDs) into 0.35T MR-Linac systems represents a significant advancement in radiotherapy, offering substantial benefits due to their tissue-e...

Characterizing an Osld Dosimetry System for Use in a Multi-Clinic Environment

Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé

Affiliation: Montefiore Medical Center

Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...

Commissioning of Varian HDR Surface Applicators Using High-Resolution Diode Array and Film Dosimetry

Authors: Milad BaradaranGhahfarokhi, Manuel A. Morales Paliza

Affiliation: Vanderbilt University Medical Center

Abstract Preview: Purpose: The purpose of this study was to commission Varian HDR surface applicators using a high-resolution diode array and film dosimetry. This work evaluates dosimetric characteristics of these appl...

Comparitive Case Analysis of Maa Mapping and Angiographic Iodinated Contrast for Y-90 SIRT Treatment Planning

Authors: Shengwen Deng, Sven L. Gallo, Robert S. Jones, David W. Jordan, Arashdeep Kaur, Aishwarya M. Kulkarni, Quibai Li, William R.M. Pedersen

Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University; Department of Radiology, Louis Stokes Cleveland VA Medical Center

Abstract Preview: Purpose:
Y-90 (Yttrium) SIRT radioembolization takes advantage of delivering localized radiation to the liver. Pre-treatment dosimetry is highly dependent on accurate MAA mapping, which may have an...

Development of a Bayesian Network for a Comprehensive Uncertainty Assessment in Personalized Dosimetry after Targeted Radionuclide Therapy

Authors: NadÚge Anizan, David Broggio, Eric Chojnacki, Estelle Davesne, Didier Franck, Stéphanie Lamart, Alexandre Pignard

Affiliation: Institut Bergonié, Service de Physique Médicale, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSN-RES/SEMIA/LSMA

Abstract Preview: Purpose: To develop an innovative method enabling a comprehensive uncertainty budget associated to personalized absorbed doses for 177Lu-PSMA therapy and providing probability distributions of all dos...

Evaluation of the Hyperscint RP-200 Plastic Scintillation Dosimetry System for Reference Dosimetry in Ultra-High Dose Rate Electron Beam Therapy: A Comparative Study

Authors: Julie Colnot, Eric Deutsch, Christelle Huet, Danahé LeBlanc, Pauline Maury, Charlotte Robert, Imane Saïd Mansour, Cathyanne Schott, Francois Therriault-Proulx

Affiliation: INSERM U1030, Gustave Roussy, University Paris-Saclay, LDRI, IRSN, Medscint, THERYQ / INSERM U1030, Gustave Roussy, University Paris-Saclay, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique

Abstract Preview: Purpose: FLASH radiotherapy, using ultra-high dose rates (UHDR, >100 Gy/s), spares healthy tissues while maintaining tumor control compared to conventional radiotherapy (CONV). However, UHDR dosimetry...

Feasibility Study of Using HDR1000+ Well-Type Ionization Chambers for Solution Based 90y Measurements

Authors: Denis Bergeron, Larry A. DeWerd, Sean Jollota, Peyton Alexandra Lalain, Likhitha Polepalli

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, National Institute of Standards and Technology

Abstract Preview: Purpose: 90Y is a challenging radionuclide to measure because it is a pure beta-emitter and is typically quantified using a radionuclide calibrator. These devices, such as the Capintec model used in t...

First in-Vivo Application of a Novel Precision Small Animal Irradiation Platform with Proton IMPT Delivery and Advanced on-Board Image-Guidance

Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers SÞrensen, Peter Thirolf

Affiliation: Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Ludwig-Maximilians UniversitĂ€t, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...

First in-Vivo Proton Radiography Experiments for an Image-Guided Small Animal Irradiation Platform with a TimePix3-Based Detector Setup

Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers SĂžrensen, Matthias WĂŒrl

Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam

Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.

Methods:...

Head and Neck Treatment Evaluation with Cone Beam Computed Tomotherapy

Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...

Impact of Beamline Mis-Adjustment Following Central Beamline Replacement for Halcyon Linear Accelerator

Authors: Emily Y. Hirata, Xiaoyu Sherry Liu, Evan Porter, Manju Sharma

Affiliation: University of California San Francisco, University of California, San Francisco, University of California

Abstract Preview: Purpose: Introduced in 2018, the Varian Halcyon platform has increased in popularity due to its reduced cost, user-friendly design, and operational efficiency. As this platform ages, major repairs, in...

Innovative Workflow for Enhanced in-Vivo Dosimetry Using Gafchromic Film

Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC

Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...

JACK KROHMER EARLY-CAREER INVESTIGATOR COMPETITION WINNER: Direct Measurement of an Early Change in Tumor Oxygenation in Response to Radiation with Oxygen Enhanced Electron Paramagnetic Resonance Imaging (OE-EPRI)

Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou

Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...

Lu-177 Recovery Coefficients Using Tc-99m Surrogate Method: Intra- & Inter-Scanner Comparison

Authors: Ben Piacitelli, Celeste Winters

Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University

Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...

Lu-PSMA-Dose, a French Retrospective Multicentric Dosimetry Study of 177Lu-PSMA Treatments for Metastatic Castration-Resistant Prostate Cancer

Authors: NadÚge Anizan, Jean-Noël Badel, Thomas Baudier, David Broggio, Désirée Deandreis, Ludovic Ferrer, Didier Franck, Camilo Garcia, Jean Gasteuil, Anne-Laure Giraudet, Olivier Humbert, Laetitia Imbert, Malick Koulibaly, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard, Caroline Rousseau, Guido Rovera, David Sarrut, Paul Schwartz, Nicolas Varmenot

Affiliation: Institut de CancĂ©rologie de l’Ouest, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de Physique MĂ©dicale, Institut BergoniĂ©, Service de Physique MĂ©dicale, CHRU de Nancy Brabois, Service de MĂ©decine NuclĂ©aire, Centre de lutte contre le cancer LĂ©on BĂ©rard, UniversitĂ© de Lyon, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, UniversitĂ© Nice CĂŽte d’Azur, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de MĂ©decine NuclĂ©aire, Institut de CancĂ©rologie de l’Ouest, Service de Physique MĂ©dicale, Service de MĂ©decine NuclĂ©aire, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSA‑Lyon, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSA‑Lyon; Centre de lutte contre le cancer LĂ©on BĂ©rard, Institut BergoniĂ©, Service de MĂ©decine NuclĂ©aire

Abstract Preview: Purpose: The main objective of the Lu-PSMA-Dose study, sponsored by ASNR, is to estimate retrospectively the individual absorbed dose delivered to patients treated with 177Lu-PSMA for metastatic castr...

Multiparametric and Low-Field MRI for Biomimetic MRI-Readable Gel Dosimeters

Authors: Kaitlyn M Betz, David Dunkerley, Eric Johnson, Kalina V Jordanova, Kathryn E. Keenan, Samuel D Oberdick, Gregory P. Penoncello, Stephen E Russek

Affiliation: Dept of Radiology, Stanford, University of Colorado School of Medicine, NIST, College of Wooster

Abstract Preview: Purpose: Examine use of low-field MRI and multiparametric analysis for 3D MRI-readable biomimetic gel dosimetry. Low-field MRIs are compact, inexpensive, and portable. They could be located within rad...

The Unspoken Impact of Couch Sag on Breathing-Traces Collected during Patient Simulation

Authors: Giorgi Archuadze, William P. Donahue, David Kanchaveli, Shih-Chi Lin, Sebastian Meyer, Grace Tang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Breathing traces captured at simulations are often used for deep-inspiration breath-hold (DIBH) treatments. However, systematic drift can occur in the traces that is unrelated to the patients...

Universal Range Modulators for Flash Proton Therapy: 3D Printing of Stackable Variable Density Units

Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...

Using Multi-Peak Reconstructions for Dosimetry of Fast and Quantitative Lutetium-177 SPECT/CT

Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija

Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging

Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...

Validating a Pre-Existing CT HU-to-Mass Density Curve for Direct Dose Calculation on High Quality Cbcts

Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray

Affiliation: University of California San Diego

Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...