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Results for "produced frg": 6 found

Development of an Ultrafast MR Technique to Detect Linac Radiation Pulses for Biological Imaging on a Clinical 0.35T MR-Linac

Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom

Affiliation: Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School

Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...

Dose Mapping of Radioactive Gold Nanoparticles Using Three-Dimensional Dosimetry

Authors: Ana Laura Burin, Maysa Müller Ferreira Gesserame, David Alexander Urbina Leal, Ilca Marli Moitinho Amaral Medeiros, Silas Leonel Pereira Miranda, Thuany Corrêa Nogueira, Maria da Penha Alburquerque Potiens, Pedro Henrique Ricardo, Maria Eduarda Zaganin Rigo, Orlando Rodrigues, Priscila Santos Rodrigues, Wilmmer Alexander Arcos Rosero, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Cristhian Ferreira Talacimon, Paulo Victor dos Santos Tavares, Lara El Hajj Teodoro, Carlos Alberto Zeituni, José Neres de Almeida

Affiliation: IPEN - USP

Abstract Preview: Purpose: Perform three-dimensional dosimetry of radioactive gold nanoparticles (¹⁹⁸AuNPs) using Fricke xylenol gel (FXG), aiming to determine the dose distribution and evaluate the method's effectiven...

Evaluation of Hybrid Dynamic Conformal Arc Planning for SRS and SBRT Treatment

Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...

Free Radical Irradiation Emergent (FIRE) MRI: Real-Time MR-Based Quantification of Radiation-Produced Free Radical Generation on a Clinical MR-Linac

Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner

Affiliation: Harvard–MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School

Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...

Integrating Multiple Modalities with Pretrained Swin Foundation Model for Head and Neck Tumor Segmentation

Authors: Jue Jiang, Aneesh Rangnekar, Shiqin Tan, Harini Veeraraghavan

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences

Abstract Preview: Purpose: Clinicians often use information from FDG-PET and CT to interpret and delineate gross tumor (GTVp) and nodal (GTVn) volumes for radiotherapy planning in head and neck (HN) cancer patients. He...

Posterior-Mean Diffusion Model for Realistic PET Image Reconstruction

Authors: Osama R. Mawlawi, Yiran Sun

Affiliation: RICE University, UT MD Anderson Cancer Center

Abstract Preview: Purpose: Conventional PET reconstruction methods often produce noisy images with artifacts due to data/model mismatches and inconsistencies. Recently, deep learning-based conditional denoising diffusi...