Authors: Ioannis Androulakis, Miranda E.M.C. Christianen, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Lorne Luthart, Remi A. Nout, Henrike Westerveld
Affiliation: Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
Despite the advantages of transrectal ultrasound-based treatment planning for HDR prostate cancer brachytherapy which allows on-line treatment delivery in the intraoperative setting, it is...
Authors: Diandra Ayala-Peacock, Lindsey Hendricks Bloom, Oana I. Craciunescu, Julie A. Raffi, Megan K. Russ, Ryan Sanford, Rajesh Venkarataman
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, Duke University Medical Center, Duke University, Eigen Health, Duke Univesity
Abstract Preview: Purpose: To establish a robust QA framework to characterize and ensure accuracy, reliability, and reusability of a transrectal ultrasound (TRUS)-based needle tracking system (NTS) for clinical HDR GYN...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Hania A. Al-Hallaq, Duncan Henry Bohannon, Chih-Wei Chang, Anees H. Dhabaan, Vishal Dhere, H Scott McGinnis, Pretesh Patel, Sagar Patel, Keyur Shah, Xiaofeng Yang, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Two-fraction proton SABR is an attractive alternative to brachytherapy for localized prostate cancer. However, potential interfractional anatomical changes necessitate online adaptation, espe...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Jeffrey Andrews, Nathan E. Becker, Juanita Crook, Andrew Jirasek, Matthew Jonathan Muscat
Affiliation: UBC, BC Cancer Agency, BC Cancer
Abstract Preview: Purpose: To map dosimetry and imaging information to ultrasound and multi-parametric magnetic resonance (mpMR) guided trans-perineal core-needle biopsies, performed during two-fraction prostate high-d...
Authors: Kevin Barker, David Jeffrey Contella, Chandima Edirisinghe, Aaron Fenster, Douglas A Hoover, Elizabeth Huynh
Affiliation: Robarts Research Institute, University of Western Ontario, London Health Sciences Center, Department of Radiation Oncology, London Health Sciences Centre
Abstract Preview: Purpose: We aim to develop a system that integrates micro-ultrasound into focal prostate cancer radiotherapy. This requires developing a mechatronic stepper capable of performing motorized rotation of...
Authors: Michael G. Mitch, Csilla I. Szabo-Foster
Affiliation: National Institute of Standards and Technology
Abstract Preview: Purpose: The U.S. air-kerma strength standard for low-dose-rate (LDR) low-energy photon-emitting brachytherapy sources provides measurement traceability for calibrations at the AAPM Accredited Dosimet...
Authors: Jaehee Chun, Jin Sung Kim, Siddhant Sen, James J. Sohn, Ethan D. Stolen
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Psychology, University of Illinois Urbana-Champaign, Oncosoft Inc
Abstract Preview: Purpose: In LDR brachytherapy for prostate cancer, anatomical changes between pre-planning and implantation require adjustment of needle and seed configurations. Currently, clinics spend significant t...
Authors: Fahad Alam, Douglas A Hoover, Raffi Karshafian, Andrew Loblaw, Lucas Mendez, Lucas Mendez, Gerard Morton, Humza Nusrat, Moti R. Paudel, Mackenzie Smith, Amandeep Tagger, Anton Varlukhin
Affiliation: Odette Cancer Center, Sunnybrook Health Sciences Center, Department of Anesthesiology, Temerty Medicine, University of Toronto, Department of Physics, Toronto Metropolitan University, Department of Radiation Oncology, Temerty Medicine, University of Toronto, Department of Radiation Oncology, London Health Sciences Centre
Abstract Preview: Purpose: Prostate brachytherapy utilization has declined, due in part to limitations seen with in-person training including time and space constraints in the operating room. Virtual reality addresses ...
Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer
Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...
Authors: Francis A Asamoah, David D. Campos, Jordan A Holmes, Ke Colin Huang, Omar Ishaq, Sook Kien Ng, Arpan Prabhu, Edwin Quashie, Yong Yue
Affiliation: Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Evaluate a novel rectal spacer workflow with spacer injection during brachytherapy to streamline logistics, reduce hospital visits and costs, and compare the benefits of SpaceOAR Vue and Barr...
Authors: Elizabeth K. Butker, Cara Cimmino, Jenna L. Fair, David Matthew Giles, Bruce Hershatter, Shadab Momin, Sagar Patel, John Pattaras, Kamran Salari Salari, Aaron Weiss
Affiliation: Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: Prostate cancer patients may experience a local-only failure after radiation. While high-dose-rate (HDR) brachytherapy may have more favorable toxicity profile and cancer control compared to ...
Authors: Rajeev K. Badkul, Ronald C Chen, Ying Hou, Harold Li, Chaoqiong Ma, Jufri Setianegara
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose:
Postimplant urinary toxicity is common in prostate low-dose-rate (LDR) brachytherapy. We developed a machine learning (ML) model to explore the correlation between spatial dose distributio...
Authors: Michael Baine, Charles Enke, Yang Lei, Yu Lei, Ruirui Liu, Su-Min Zhou
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Radiation Oncology, University of Nebraska Medical Center
Abstract Preview: Purpose: This study presents a framework for generating synthetic CT images using a Cycle Diffusion model, which can be utilized to enhance needle conspicuity in ultrasound-guided prostate HDR brachyt...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...