Authors: Suman Gautam, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-speciïŹc quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...
Authors: Jeffrey Bax, Ian A. Cunningham, Aaron Fenster, Lori Gardi, Sule Karagulleoglu Kunduraci, Alla Reznik, David Tessier
Affiliation: Robarts Research Institute, Imaging Research Laboratories, Robarts Research Institute, Lakehead University
Abstract Preview: Purpose: Image-guided biopsy is critical for early diagnosis of prostate cancer (PCa), the most common cancer in men worldwide. While the prostate-specific PET (P-PET) system offers enhanced sensitivi...
Authors: Christopher Colyer, Leon F Dunn, Jonathan Dunning, Simon Goodall, Andy Schofield
Affiliation: GenesisCare
Abstract Preview: Purpose: Modern radiotherapy is characterized by complex treatment plans utilizing dynamic MLCs, gantry positions and recently, collimator rotations. The purpose of this work was to compare the plan c...
Authors: Benjamin W. Maloney, Ashley E. Rubinstein, Colin Schaeffer, Justin Yu
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Radiography AEC systems ensure correctly exposed images for varied kVp and patient thicknesses. The specific kVp and PMMA thicknesses selected for testing AEC tracking may affect passing rate...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...
Authors: Amir Abdollahi, Celine Karle, Michele M. Kim, Constantinos Koumenis, Andrea Mairani, Erato Stylianou Markidou
Affiliation: Heidelberg Ion-Beam Therapy Center - Department of Radiation Oncology, German Cancer Research Centre(DKFZ), University of Pennsylvania, Physics Dep. University of Cyprus
Abstract Preview: Purpose: The aim is to compare FLASH dose-rate RT generated with protons and carbon (HIT) and compare to protons (UPenn) to provide evidence for equipotency of FLASH vs. standard RT to tumor growth co...
Authors: Maria Jose Almada, Bruno Forti, Andres Lima, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
To automate the planning of radiotherapy treatments for bone metastases using a script in the ECLIPSE planning system version 15.6 with a graphical interface.
Methods:
A script was d...
Authors: Maria Jose Almada, Bruno Forti, Patricia Murina, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie, Dra.
Abstract Preview: Purpose: The use of VMAT for the breast requires duplication of the patient's CT, several planning structures, and patient-specific dose-volume constraints depending on the patient's anatomy, fraction...
Authors: Sophie Boisbouvier, David Cobben, Anthony L Criscuolo, Michael W. Kissick, Mark Ramtohul, Gordon Sands, Tracy Underwood
Affiliation: University of Surrey, Department of Medical Physics, Queen Elizabeth Hospital, Lung Cancer and Sarcoma Radiotherapy, The Clatterbridge Cancer Centre, Leo Cancer Care, Radiotherapy department, Centre Léon Bérard
Abstract Preview: Purpose:
Pulmonary function tests (PFTs) help assess treatment options for lung cancer patients. Conventionally, these are undertaken upright, whereas radiotherapy is administered supine. This stud...
Authors: NadÚge Anizan, David Broggio, Eric Chojnacki, Estelle Davesne, Didier Franck, Stéphanie Lamart, Alexandre Pignard
Affiliation: Institut Bergonié, Service de Physique Médicale, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSN-RES/SEMIA/LSMA
Abstract Preview: Purpose: To develop an innovative method enabling a comprehensive uncertainty budget associated to personalized absorbed doses for 177Lu-PSMA therapy and providing probability distributions of all dos...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Pak Hang Nam, Mei Yan Tse, Jierong Wang, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: Intrafraction motion management remains a major challenge in magnetic resonance-guided radiotherapy (MRgRT). The recent clinical release of an active motion management system aims to enhance ...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko SalomĂłn Alva SĂĄnchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Martin Auerbach, Jeremie Calais, Johannes Czernin, Magnus Dahlbom, Zachary Ells, Adrien Holzgreve, Koichiro Kimura, Karam Masri, Catherine (Caffi) Meyer, David Sennung
Affiliation: Department of Nuclear Medicine, UCLA, UCLA, University of California, Los Angeles
Abstract Preview: Purpose: Lutetium-177 PSMA SPECT/CT imaging offers the possibility of qualitative image analysis for tumor response assessment and quantitative image analysis for individualized dosimetry. However, th...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers SĂžrensen, Matthias WĂŒrl
Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam
Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.
Methods:...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: Steve B. Jiang, Chien-Yi Liao, Dan Nguyen, Daniel Yang, Hengrui Zhao
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Post-operative radiotherapy for prostate cancer requires precise contouring of the clinical target volume (CTV) to account for microscopic disease that is invisible in the image. However, ...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran
Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine
Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...
Authors: Maya Ataya, Clint Bahler, Ramotallah Dami Jubril, Michael Koch, Oluwaseyi Oderinde, Mark Tann
Affiliation: Purdue University, epartment of Urology, Indiana University School of Medicine, Department of Urology, Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indiana University School of Medicine
Abstract Preview: Purpose:
To investigate racial differences in the detection of biochemical recurrence (BCR) using 68Ga-PSMA-11 PET/CT, known for its improved sensitivity and specificity in patients after radical p...
Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong
Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University
Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...
Authors: NadÚge Anizan, Jean-Noël Badel, Thomas Baudier, David Broggio, Désirée Deandreis, Ludovic Ferrer, Didier Franck, Camilo Garcia, Jean Gasteuil, Anne-Laure Giraudet, Olivier Humbert, Laetitia Imbert, Malick Koulibaly, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard, Caroline Rousseau, Guido Rovera, David Sarrut, Paul Schwartz, Nicolas Varmenot
Affiliation: Institut de CancĂ©rologie de lâOuest, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de Physique MĂ©dicale, Institut BergoniĂ©, Service de Physique MĂ©dicale, CHRU de Nancy Brabois, Service de MĂ©decine NuclĂ©aire, Centre de lutte contre le cancer LĂ©on BĂ©rard, UniversitĂ© de Lyon, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, UniversitĂ© Nice CĂŽte dâAzur, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de MĂ©decine NuclĂ©aire, Institut de CancĂ©rologie de lâOuest, Service de Physique MĂ©dicale, Service de MĂ©decine NuclĂ©aire, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSAâLyon, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSAâLyon; Centre de lutte contre le cancer LĂ©on BĂ©rard, Institut BergoniĂ©, Service de MĂ©decine NuclĂ©aire
Abstract Preview: Purpose: The main objective of the Lu-PSMA-Dose study, sponsored by ASNR, is to estimate retrospectively the individual absorbed dose delivered to patients treated with 177Lu-PSMA for metastatic castr...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...
Authors: Michael M Folkerts, Miriam Krieger, Pierre Lansonneur, Gerard Paquet, Petar Penchev, Christoph Schuy, Yuri Simeonov, Uli Weber, Klemens Zink
Affiliation: GSI Helmholtzzentrum fuer Schwerionenforschung, Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences, Varian Medical Systems
Abstract Preview: Purpose:
Ultra-high dose-rate proton irradiation may spare the healthy tissue (FLASH-effect). The 3D-range-modulator (3D-RM) method reduces the treatment time compared to conventional IMPT and can ...
Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb
Affiliation: GenesisCare
Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...
Authors: Manju Liu, Ning Wen, Fuhua Yan, Yanzhao Yang, Zhenyu Yang, Haoran Zhang, Lei Zhang, Yajiao Zhang
Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy where precise segmentation of tumors and adjacent vessels is crucial for effective treatment planning. This study dev...
Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-ChacĂłn, Alejandro Rodriguez-Laguna
Affiliation: UNAM, Medica Sur
Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...
Authors: Vasiliki Chatzipavlidou, Ilias Gatos, George C. Kagadis, Theodoros Kalathas, Paraskevi Katsakiori, Anna Makridou, Dimitris N. Mihailidis, Nikos Papathanasiou, Ioanna Stamouli, Stavros Tsantis
Affiliation: Theageneio Hospital, University of Pennsylvania, University of Patras
Abstract Preview: Purpose: To compare the performance of multiple deep learning (DL) networks, including DenseNet201, InceptionV3, MobileNetV3, EfficientNetB2, NASNetMobile, VGG19, ResNet50, and Xception, in classifyin...
Authors: NadÚge Anizan, David Broggio, Désirée Deandreis, Didier Franck, Camilo Garcia, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard
Affiliation: Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, Gustave Roussy, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS
Abstract Preview: Purpose: This work aimed at developing an innovative workflow for 177Lu-PSMA personalized dosimetry to lesions and organs at risk (OAR) simultaneously, considering the cross-irradiation from bone meta...
Authors: David Alcorta, Joseph Farina, Timothy Haystead, Yiping He, Philip Hughes, David Loiselle, Marybeth Nedrud, Victoria J. P. Radosova, Jianpeng Yu
Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Duke University School of Medicine, Duke Cancer Institute
Abstract Preview: Purpose: Targeted radiopharmaceuticals have become of widespread interest in the scientific community given their ability to detect and treat metastatic disease. We aim to validate the use of novel ch...
Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer
Affiliation: UCLA, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...
Authors: Elizabeth K. Butker, Cara Cimmino, Jenna L. Fair, David Matthew Giles, Bruce Hershatter, Shadab Momin, Sagar Patel, John Pattaras, Kamran Salari Salari, Aaron Weiss
Affiliation: Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: Prostate cancer patients may experience a local-only failure after radiation. While high-dose-rate (HDR) brachytherapy may have more favorable toxicity profile and cancer control compared to ...
Authors: Anahita Bakhtiari Moghaddam, Don F. DeJongh, Ethan DeJongh, Jennifer Hardt, Oliver JĂ€kel, Lukas Martin, Alexander Pryanichnikov, Joao Seco, Christina Stengl, Niklas Wahl
Affiliation: Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Division of Biomedical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), ProtonVDA LLC, Department of Physics and Astronomy, Heidelberg University, Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT)
Abstract Preview: Purpose:
To evaluate the feasibility and performance of single-plane position tracking for proton and helium pencil beam radiography using a prototype imaging system, with the goal of providing a c...
Authors: Asma Amjad, Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate and precise linac-based SRS commissioning can be very challenging. Thus, it is important to increase the confidence in the measurement at each step prior to end-to-end testing. The p...
Authors: Guillermo Daniel Alvarez, Daniel Fino, Rocio Luz Gilli, Dorian Alexander Romero
Affiliation: School Foundation of Nuclear Medicine, INTECNUS Foundation, Nuclear Medicine and Radiotherapy Center of Southern Patagonia
Abstract Preview: Purpose: To evaluate the anatomical, functional, and molecular information from PET/MR images with F18-PSMA to identify intraprostatic lesions and delineate a boost in stereotactic body radiotherapy (...
Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija
Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging
Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...