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Results for "quantitative maximum": 23 found

A Patient-Specific Approach to Surface Guided-DIBH SBRT Candidacy Using Surface Deformation Maps

Authors: Savannah Decker, Grace Gwe-Ya Kim, Laura Padilla

Affiliation: UC San Diego, University of California San Diego

Abstract Preview: Purpose: The success of surface-guided deep-inspiration breath-hold (SG-DIBH) treatments depends on accurate identification of suitable candidates. Sub-optimal patient selection can result in prolonge...

A Robust Quantitative Metric for Optimal Beam Selection in Radiotherapy of the Peripheral Lung Lesions: A Crucial Step in Standardization of Lung SBRT

Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...

Automated Quantitative Method for Source Position Calculation in Annual Quality Assurance of High Dose Rate Brachytherapy Gynecological Applicators

Authors: Ivan M. Buzurovic, Matthew W. Jacobson, Marjan Khosravi

Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Massachusetts Lowell, Department of Physics, Lowell, MA/Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Annual quality assurance (QA) of high dose rate (HDR) brachytherapy (BT) gynecological (GYN) applicators is critical to ensure accurate and consistent source position and dose delivery. In th...

BEST IN PHYSICS ULTRASOUND: A Calibration Framework for Quantifying Element Misalignment in 2D Matrix Array Transducers Used in 3D Quantitative Ultrasound

Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez

Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison

Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...

Decreasing the Dependence of CT Number on the Position in the Field-of-View Using Photon Counting Detector CT

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...

Dependency of CT Number on Position in the Field-of-View for Single- and Multi-Energy Images Acquired with Energy-Integrating-Detector and Photon-Counting-Detector CT Scanners

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...

Development of Sphere Phantoms for Quantitative Evaluation of Computed Tomography Systems Resolution

Authors: Hyo-Min Cho, Changwoo Lee

Affiliation: Korea Research Institute of Standards and Science

Abstract Preview: Purpose: We develop sphere phantoms to assess spatial resolution of computed tomography (CT) systems and validate its usability using table-top X-ray experiment systems.
Methods: We manufactured sp...

Direct Table Rotational Isocenter Determination Using Radiation Isocenter

Authors: Christopher Ackerman, Chang Chang, Yansong Liu, Stephen Kenneth Northway, Bailey Vallejo

Affiliation: University of California San Diego / California Protons, California Protons Cancer Therapy Center, California Proton Cancer Therapy Center

Abstract Preview: Purpose: To determine mechanical isocenter of a 6-degree-of-freedom (6DOF) couch using radiation isocenter. Coincidence between the isocenters is quantified using MyQA Phoenix amorphous silicon detect...

Evaluation of an Analytical Simulation Technique By Comparing Transmitted Spectra Against GEANT4 through a Hafnium-Loaded Heterogeneous Phantom

Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...

Expert Verification of AI-Generated Cardiac Substructures and Dosimetric Differences between Auto-Contoured and Manually Delineated Contours

Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding

Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington

Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...

Exploring Quantifiable Features of the Fracture Healing Process

Authors: Jung Gyu Chi, Sungwook Choi, Don-Soo Kim

Affiliation: IAM ORTHOPAEDIC CLINIC, Boston Children's Hospital/Harvard Medical School, Massachusetts College of Pharmacy and Health Science

Abstract Preview: Purpose: To explore quantifiable parameters of the fracture healing process to aid physicians in determining the treatment plan for intramedullary nailing removal.
Methods: In contrast to conventio...

Graph-Based Feature Selection to Improve Stability and Reproducibility of CT-Based Radiomics in Head and Neck Squamous Cell Carcinoma: A Cross-Institutional Study

Authors: Daria Gaykalova, Ranee Mehra, Jason K Molitoris, Hajar Moradmand, Lei Ren, Amit Sawant, Phuoc Tran

Affiliation: University of Maryland School of Medicine, Maryland University Baltimore, University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: Radiomics extracts quantitative imaging biomarkers from medical images. However, maintaining the reproducibility and stability of selected features across institutions and parameter settings ...

Improving Quantitative Accuracy of Maximum-a-Posteriori Expectation Maximization Reconstruction By Optimizing Gibbs Prior Parameters in SPECT

Authors: Krishnendu Saha

Affiliation: Cleveland Clinic Foundation

Abstract Preview: Purpose: The goal is to improve quantitative accuracy of a Maximum-a-posteriori expectation maximization (MAPEM) reconstruction of SPECT phantom images by optimizing Gibbs prior parameters.
Methods...

Initial Phantom Studies Towards Implementation of Sequential Dual Energy CBCT on an Adaptive Radiotherapy Linac Platform

Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam

Affiliation: University of Michigan

Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...

Investigation of Fluorescent Probes for Real-Time ROS Detection Under Flash Radiotherapy

Authors: Yuqi Yang, Fang-Fang Yin

Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...

Multidimensional Diffusion MRI Based Microstructural Heterogeneity Model on a 5T MR System

Authors: Jiayi Chen, Shaolei Li, Fuhua Yan, Yingli Yang, Jie Zhang

Affiliation: Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai United imaging Healthcare Advanced Technology Research Institute, Department of Radiation Oncology, Ruijin Hospital

Abstract Preview: Purpose: The aim of this exploratory study is to investigate the feasibility of establishing a model to explore tissue component heterogeneity using multidimensional diffusion magnetic resonance imagi...

Optimizing Dosimetry in Rpt Clinics: Tackling Initial Hurdles and Ensuring Image Accuracy.

Authors: Siju C. George, Alonso N. Gutierrez, Vivek Mishra, Ranjini P. Tolakanahalli

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute

Abstract Preview: Purpose: This presentation focuses on optimizing dosimetry in RPT clinics by tackling initial setup challenges and ensuring the accuracy of SPECT/CT imaging for dosimetry. It will address the qualific...

Preclinical Assessment of Novel Targeted Chelate-Based Radiopharmaceuticals for Aggressive Cancer Detection

Authors: David Alcorta, Joseph Farina, Timothy Haystead, Yiping He, Philip Hughes, David Loiselle, Marybeth Nedrud, Victoria J. P. Radosova, Jianpeng Yu

Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Duke University School of Medicine, Duke Cancer Institute

Abstract Preview: Purpose: Targeted radiopharmaceuticals have become of widespread interest in the scientific community given their ability to detect and treat metastatic disease. We aim to validate the use of novel ch...

Quantitative Analysis of Three Strategies for CTPA Scan Timing Optimization

Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz

Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison

Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...

Quantitative Evaluation of Eclipse’s (V18) Ability to Address Dosimetric Leaf Gap Variations

Authors: D. Michael Lovelock, Charlotte Elizabeth Read, Ren-Dih Sheu, Jing Wang, Tingyu Wang

Affiliation: Icahn School of Medicine at Mount Sinai, Jersey Shore University Medical Center

Abstract Preview: Purpose:
Early Eclipse models use rectangular fluence profiles (widened by the dosimetric leaf gap (DLG) to account for the fact that leaf tips are rounded). Eclipse Version 18 (V18) uses enhanced ...

Quantitative Image Review Metric for Vertebral Body Misalignment

Authors: Luis E. Fong de los Santos, Douglas John Moseley, Satomi Shiraishi, Cenji Yu

Affiliation: Mayo Clinic

Abstract Preview: Purpose: To quantitatively detect errors in vertebral body localization using normalized cross correlation (NCC)

Methods: Volumetric images of a thoracic end-to-end SBRT phantom with a removabl...

Serial PET-CT Activity Concentration during Small Target Lung Tumor SBRT

Authors: Joseph Barbiere, Joseph Hanley, Brett Lewis, Jay Mistry, Alois M. Ndlovu, Roland Teboh

Affiliation: Hackensack University Medical Center, HUMC, Jersey Shore University Medical Center

Abstract Preview: Purpose:
Quantitative PET-CT can evaluate clinical response to radiotherapy. For tumors less than approximately 3cm partial volume effects due to the poor PET resolution makes accurate measurement ...

Sources of Variability in Evaluating Ultrasound Imaging Performance Using Randomly-Distributed Hypoechoic Sphere Phantom

Authors: Cristel Baiu, Zheng Feng Lu, Dufan Wu, Baihui Yu

Affiliation: University of Wisconsin, Massachusetts General Hospital, University of Chicago

Abstract Preview: Purpose: IEC TS 62791:2022 specified a clinically meaningful and quantitative framework for evaluating diagnostic ultrasound performance by measuring the lesion signal-to-noise ratio (LSNR) using rand...