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Results for "radical generation": 2 found

Development of an Ultrafast MR Technique to Detect Linac Radiation Pulses for Biological Imaging on a Clinical 0.35T MR-Linac

Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom

Affiliation: Brigham and Women’s Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School

Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...

Free Radical Irradiation Emergent (FIRE) MRI: Real-Time MR-Based Quantification of Radiation-Produced Free Radical Generation on a Clinical MR-Linac

Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner

Affiliation: Harvard–MIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School

Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...