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A Comparative Analysis of Hand Calculations and Macro Monte Carlo Simulations for Electron Beam Dosimetry

Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr

Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado

Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...

A Comparison of on-Isocenter Vs Off-Isocenter Planning for Lung SBRT on the Viewray Mridian

Authors: Nebi Demez, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Treatment plans on the ViewRay MRIdian are often planned with the target placed off isocenter due to the proximity of the bore to the patient, allowing for limited shifts. This is especially ...

A Dosimetric Analysis of Lu-177-Based Radiopharmaceutical Therapy for Optimizing Therapeutic Ratio

Authors: Travis James McCaw, Ravi Patel, Abdelhamid Saoudi, Joseph Shields

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, UPMC

Abstract Preview: Purpose: The current treatment approach for Lu-177-based radiopharmaceutical therapy involves multiple administrations, each delivering a constant activity of 200 mCi. This study evaluates whether the...

A Novel Cost-Effective Customizable 3D-Printed Thoracic Phantom for End-to-End Treatment Verification and Image Quality Assessment

Authors: Reza Farjam, Russell K Hales, Seth Jayawardane, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins School of Medicine

Abstract Preview: Purpose: This study presents a novel cost-effective customizable 3D-printed phantom developed for end-to-end treatment verification and image-quality assessment for thoracic applications.
Methods: ...

A Radiomic Quantification Framework for Hyperparameter Optimization in Texture Characterization

Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu

Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...

Advocating for Survival Prediction Models in Risk Stratification for Cancer Treatment Outcomes

Authors: Meixu Chen, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Cancer treatment outcome prediction plays a pivotal role in guiding therapeutic decisions and optimizing patient care. Traditionally, binary prediction models have been widely used for risk s...

An Analytical Approach to Monitor Unit Calculation in Extended Distance Total Body Irradiation (TBI)

Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav

Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine

Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...

Assessing Accessibility for the Visually Impaired in Medical Physics Training

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan

Affiliation: The Ohio State University James Cancer Hospital, The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital

Abstract Preview: Purpose: Accessibility is a topic of increasing importance in many fields, and medical physics is no exception. While the traditional educational pathway presents a plethora of challenges for the visu...

Assessment of Deep Learning Models for 3D Dose Prediction in Prostate Cancer SIB-IMRT Using MR-Linac

Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan

Affiliation: University of Florida

Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...

Assessment of Image Quality and Dose in Dual-Energy X-Ray Imaging for Lung Tumor Tracking

Authors: Nawal Alqethami, Felix Ginzinger, Prasannakumar Palaniappan, Marco Riboldi, Philipp Steininger, Wentao Xie

Affiliation: Research & Development, medPhoton GmbH, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich)

Abstract Preview: Purpose:
This study evaluates the image quality of Dual-Energy (DE) X-ray imaging for lung tumor tracking across various sizes and protocols, comparing its imaging dose to Single-Energy (SE) imagin...

Automated IMPT Treatment Planning for CSI: Enhancing Efficiency with Auto-Segmentation and Scripting

Authors: Katja M. Langen, William Andrew LePain, Robert Muiruri, Vivi Nguyen, Mosa Pasha, Roelf L. Slopsema, Alexander Stanforth, Yinan Wang, Mingyao Zhu

Affiliation: Emory Healthcare, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) treatment planning for craniospinal irradiation (CSI) is complex and requires extensive effort from the planner. This study aims to enhance planning ...

BEST IN PHYSICS THERAPY: Overcoming Challenges in Developing Machine Learning-Driven Acute Kidney Injury Predictive Models Using Non-Standard Emrs in Resource-Limited Settings

Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou

Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, People’s Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital

Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...

BEST IN PHYSICS ULTRASOUND: A Calibration Framework for Quantifying Element Misalignment in 2D Matrix Array Transducers Used in 3D Quantitative Ultrasound

Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez

Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison

Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...

Comparative Evaluation of Spekpy for Kilovoltage Beam Quality Characterization

Authors: Chang Heon Choi, Yoonsuk Huh, Jin Jegal, Seonghee Kang, Jung-in Kim, Inbum Lee, Hyojun Park

Affiliation: Department of Radiation Oncology, Seoul National University Hospital

Abstract Preview: Purpose: This study evaluates SpekPy, a Python-based tool for modeling kilovoltage (kV) x-ray spectra, by comparing its calculated energy spectra, half-value layer (HVL), and air kerma with experiment...

Comprehensive Commissioning of an O-Ring-Shaped Image-Guided Radiotherapy System with a Gimbal-Mounted Linear Accelerator

Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago

Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University

Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...

Construction and Application Study of a Deep Learning-Based Iscout-Guided Precision Radiotherapy Positioning Error Prediction Model for Breast Cancer

Authors: Fangfen Dong, Jiaming Li, Xiaobo Li, Weipei Wang, Zhixin Wang, Bing Wu, Benhua Xu, Yong Yang, Yifa Zhao

Affiliation: Department of Radiation Oncology, Fujian Medical University Union Hospital/Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors/Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematologi, Zhangpu County Hospital, School of Medical Imaging, Fujian Medical University

Abstract Preview: Purpose: To explore the construction and clinical application value of a deep learning-based positioning error prediction model, providing a reference for optimizing iSCOUT system-guided precision rad...

Correction Factors for Estimating Skin Dose from Overresponse of Two Commercial Optically Stimulated Luminescence Dosimeters

Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine

Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...

Determine Noise Weighting Factor in Photon-Counting CT Via Deep Learning for Personalized Noise Reduction

Authors: Xinhui Duan, Roderick W. McColl, Mi-Ae Park, Liqiang Ren, Gary Xu, Kuan Zhang, Yue Zhang

Affiliation: UT Southwestern Medical Center, Department of Radiology, UT Southwestern Medical Center, Imaging Services, UT Southwestern Medical Center

Abstract Preview: Purpose:
Image-based deep-learning noise-reduction techniques have been developed for photon-counting CT (PCCT) to improve image quality with reduced radiation dose. The denoising strength is typic...

Developing a Dataset for Investigations into the Impact of CT Acquisition and Reconstruction Conditions on Quantitative Imaging Using Paired Image Quality and Radiomics Phantom Data

Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese

Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory

Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...

Development of a High-Speed Digital Breast Tomosynthesis System with a Two-Dimensional Multiple X-Ray-Source Array

Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski

Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health

Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...

Direct Measurement of DNA Damage to Determine Dose and Biological Effectiveness

Authors: Michael Lamontagne, Ileana Pazos, Jerimy C. Polf, Joseph W. Robertson, Teniola Tobun, Ronald E. Tosh, Michael Zwolak

Affiliation: Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, M3D, Inc, National Institute of Standards and Technology, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology

Abstract Preview: Purpose: To study how damage to DNA molecules increases and changes as a function of the type and dose of radiation.

Methods: DNA molecules of a known length (number of base pairs (BP)) within ...

Eclipse AFI Manual Planning Versus Brainlab Auto-Planning: A Comparison of SRS Plan Quality

Authors: Dharmin D. Desai, Ellis Lee Johnson, Philip J. Kallenberg, Kapil M. Mishra

Affiliation: Spectrum Medical Physics, University of Kentucky, Varian Advanced Oncology Solutions

Abstract Preview: Purpose: The “Ask For It” (AFI) manual optimization strategy has been shown to generate high quality SRS plans within Eclipse. The purpose of this work is to directly compare manually generated Eclips...

Effect of Variation in the α/β of Cervical Cancer on Clinical Outcomes of Radiation Therapy

Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington

Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky

Abstract Preview: Purpose: To investigate the effect of variation in the α/β of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...

Enhanced Prediction of Iroc Stereotactic Radiosurgery Phantom Audit Results with Treatment Parameters, Complexity Metrics, DVH, and Dosiomics Using Machine Learning

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Christine Peterson, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop predictive models for IROC SRS head phantom audits and to identify important factors influencing institutional performance.
Methods: The IROC SRS head phantom includes two TLDs ...

Evaluation of Charge Collection Performance in the A30 Prototype Parallel Plate Ion Chamber in Ultra-High Dose Rate Beam

Authors: Mervat A. Alharbi, Wesley S. Culberson

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Medical Physics Department, School of medicine and Public Health, University of Wisconsin-Madison

Abstract Preview: Purpose: The charge collection using ionization chambers is challenging at ultra-high dose rates (UHDR) due to the high ion recombination The Exradin A30 prototype parallel-plate ion chamber manufactu...

Evaluation of the Extrapolated Output Factors of Varian's Halycon Beam Model for Fields Smaller Than 1 Cm with AAA and Acurosxb

Authors: Arjit K. Baghwala, Devin J. Olek, Parth K. Patel, Ramiro Pino, Adam Yanez

Affiliation: Houston Methodist Hospital, Kaiser Permanente

Abstract Preview: Purpose: The Halcyon beam model in Eclipse is immutable and only includes output factors (OF) for fields down to 1x1 cm2. The TPS must extrapolate OFs for smaller fields used in stereotactic (SRS/SBRT...

Feasibility of Zap-X Beam Quality Assurance Using Cherenkov Radiation

Authors: Xiaodong Wu, Xingchen Zhai, Weizhao Zhao

Affiliation: University of Miami

Abstract Preview: Purpose: The ZAP-X is a self-contained, self-shielded radiosurgery system utilizing a 3MV LINAC. Its self-shielded design, poses challenges for conventional beam quality assurance (QA) methods. This s...

Field Output Correction Factors of Novel Shielded and Unshielded Silicon Diode Detectors

Authors: Mohamad Ahmad Alissa, Carson Brame, Damian Czarnecki, Olivier Evrard, Charbel A. Habib, Jeff Hildreth, Andy Murray, Andreas Schönfeld, Ann-Britt Schönfeld, David Towle, Gerd Wessing

Affiliation: CDT-West - Centrum für Diagnostik und Therapie, Radiologie Vechta, Technische Hochschule Mittelhessen, MyMichigan Health, Sun Nuclear Corp., Mirion Technologies

Abstract Preview: Purpose: To characterize field output correction factors of novel shielded and unshielded silicon diode detectors.
Methods: Novel shielded and unshielded Silicon Diode Detectors (SDD) were characte...

Formulation of Equivalent Dose in 2-Gy Fractions (EQD2) Based on the Linear-Quadratic-Linear (LQL) Model from First Principles

Authors: Makunda Aryal, Qiongge Li, Sook Kien Ng, Christopher F. Njeh, Edwin Quashie, Senthamizhchelvan Srinivasan, Yun Wang

Affiliation: Indiana University Medical School, Memorial Health Care System, Indiana University, Inova Hospital, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Linear-Quadratic-Linear (LQL) model is a modification of the traditional Linear-Quadratic model used in radiobiology to describe cell survival in response to radiation. The LQL model extends ...

Impact of Arc Number Variation on VMAT Lattice Radiotherapy Plans

Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu

Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...

Investigating Factors Impacting the Consistency of Signal-to-Noise Ratio in Mammographic Automatic Exposure Control

Authors: James Ward, Anzi Zhao

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: This study investigates the impact of tissue-equivalent attenuator materials, the region of interest (ROI) size, and the orientation of the attenuator positioning on the measured signal-to-no...

Investigation and Machine-Learning Modeling of Dosimetric Discrepancies in Eclipse-Calculated Head and Neck Treatment Plans

Authors: Andres Portocarrero Bonifaz, Ian Schreiber

Affiliation: CARTI Cancer Center

Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...

Investigation into the Robustness of Spine Stereotactic Body Radiotherapy Plans to Patient Setup Errors

Authors: Yukio Fujita, Syoma Ide, Fumiki Ito, Kei Ito, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki, Riku Watanabe

Affiliation: Komazawa University Graduate School, Komazawa University, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

Abstract Preview: Purpose: Spine stereotactic body radiotherapy (SBRT) demands high precision due to the target's proximity to the spinal cord and steep dose gradients, which complicate treatment planning. Consequently...

Knowledge-Based Three-Dimensional Dose Prediction for High Dose Rate Prostate Brachytherapy

Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi

Affiliation: UC San Diego, Virginia Commonwealth University

Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...

Long-Term Stability Assessment of an Imaging Ring System Using One Year of Monthly Quality Assurance Data

Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...

Lung Nodule Volume Estimation: Performance of Conventional Energy-Integrating and Cdznte-Photon-Counting CT Using Hybrid Reconstruction Method

Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Luuk J Oostveen, Elsa Bifano Pimenta, Ioannis Sechopoulos, Alessandra Tomal

Affiliation: Radboud University Medical Center, University of São Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin

Abstract Preview: Purpose: The study evaluated the accuracy and precision of lung nodule volume measurements, specifically solid nodules (SNs) and ground-glass opacities (GGOs) in different imaging settings.
Methods...

Multi-Institutional Evaluation of Radiographic Automatic Exposure Control Performance Testing: Methodology, Outcomes, and Failure Rates

Authors: Caroline Cheney, Nicole M. Lafata, Zaiyang Long, Dustin W. Lynch, Erin B. Macdonald, Andy Madore, Douglas E. Pfeiffer, Colin Schaeffer, Alexander W. Scott

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, UVA Health, Duke University Health System, Mayo Clinic, Henry Ford Health, Boulder Community Health, Varian, Cedars-Sinai Medical Center

Abstract Preview: Purpose: This work evaluates the significance of performing established radiography automatic exposure control (AEC) tests by comparing testing methodology, outcomes, and failure rates across multiple...

Optimizing Low-Dose Imaging Parameters for Dual-Energy Cone-Beam Computed Tomography in Image-Guided Radiation Therapy

Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske

Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...

PET Guided Radiation Therapy for Large Planning Target Volume Expansions of Small PET-Active Gross Tumor Volumes

Authors: Sarah Dumont, Trevor Ketcherside, An Liu, William T. Watkins, Qiuyun Xu

Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose:
The RefleXion X1 SCINTIX algorithm convolves beam fluence with real-time PET distributions for tracking and plan adaptation, but radiotherapy Planning Target Volumes (PTVs) are often signi...

Patient-Specific Quality Assurance in SBRT Treatments Using 3D Polymer Gel Dosimetry

Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna

Affiliation: UNAM, Medica Sur

Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...

Performance Comparison of Artificial Intelligence-Based Auto-Segmentation Software on Pediatric CT Image Datasets for the Creation of Patient Specific Computational Phantoms

Authors: Wesley E. Bolch, Emily L. Marshall, Dhanashree Rajderkar, Wyatt Smither

Affiliation: University of Florida

Abstract Preview: Purpose: To determine the accuracy of TotalSegmentator, an AI-based automatic segmentation toolkit, on pediatric CT scans as the original software was trained on adult image datasets with a mean patie...

Performance Evaluation of CT-Based Lung Tumor Classification Deep Learning Algorithms Under Centralized and Federated Learning Frameworks

Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou

Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...

Personalized Organ Dose Estimation Using Monte Carlo Simulations, Auto-Segmentation, and Anatomical Extension from Clinical CT Scans

Authors: Belen Juste, Choonsik Lee, Matthew Mille, Rafael Miró, Sergio Morato Rafet, Agustin Santos, Gumersindo Verdú

Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Universitat Politècnica de València, Servicio de Radiofísica y Protección Radiológica, Consorcio Hospitalario Provincial de Castellón, National Cancer Institute

Abstract Preview: Purpose: To evaluate the differences in CT scan radiation dose estimation between personalized dose reconstruction, based on real patient CT images, and generalized phantom-based dose calculations.

Quality Assurance Program for Dual Energy Subtraction Imaging-Based Markerless Tumor Tracking

Authors: Hyejoo Kang, Andrew Keeler, Mathias Lehmann, Jason Patrick Luce, Ha Nguyen, John C. Roeske

Affiliation: Varian Imaging Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose: Markerless tumor tracking (MTT) using dual-energy (DE) subtraction imaging is being considered as a non-invasive method to track tumors during lung cancer treatment. Prior to clinical impleme...

Quantifying the Impact of Tissue Inhomogeneities on Calculated Dosimetry within LDR Brachytherapy

Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson

Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer

Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...

Spherical Slicing and Convolutions for Accurate Glioma Tumor Segmentation Using Multi-Parametric MRI

Authors: Ke Lu, Chunhao Wang, Ruoxu Xia, Zhenyu Yang, Fang-Fang Yin, Chulong Zhang, Lei Zhang, Rihui Zhang, Jingtong Zhao, Haiming Zhu

Affiliation: Duke University, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: The human brain’s spherical geometry offers unique opportunities for improving the segmentation of tiny and irregular anatomical structures. We hypothesize that representing the brain in sphe...

Streamlining Orthovoltage QA: Feasibility of IC Profiler Dosimetry and Workflow Optimization

Authors: Huixiao Chen, Zhe (Jay) Chen, MinYoung Lee, Sameer Taneja

Affiliation: Yale School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: Superficial radiation therapy uses low-energy x-rays to treat various types of cancers, including non-melanoma skin cancers, and dermatological conditions such as keloid scars, mycosis fungoi...

To Assess and Monitor the Characteristics of Scanning Proton Beam Utilizing the Xrv-124 Scintillator Device

Authors: Liang-Hsin Chen, Hsiang-Kuang Tony Linag

Affiliation: National Taiwan University Cancer Center, Department of Biomedical Engineering, National Taiwan University

Abstract Preview: Purpose: The characteristics of scanning proton beam is one of crucial factors to affect dose delivering accuracy in proton theray. Therefore, this study aims to evaluate and monitor the stability of ...

Universal Range Modulators for Flash Proton Therapy: 3D Printing of Stackable Variable Density Units

Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...

Validation and Benchmarking of Mirdct Software for Organ Dose Estimation in Routine CT Protocols

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Gunjan Kayal, Adam Leon Kesner, Harry Marquis, Juan Camilo Ocampo Ramos, Stefan Wehmeier

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: Accurate organ dose estimation in computed tomography (CT) has gained attention due to the increasing global utilization of CT imaging. MIRDct, a specialized CT dosimetry software, has recent...