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Results for "read factor": 60 found

A Causal Machine Learning Analysis of Dosimetric and Clinical Predictors of Osteoradionecrosis in Head and Neck Cancer Radiotherapy

Authors: Jingyuan Chen, Sheng Li, Tianming Liu, Wei Liu, Zhengliang Liu, Zhong Liu, Daniel Ma, Samir H. Patel, Guangya Wang, Yunze Yang

Affiliation: University of Miami, Mayo Clinic, School of Data Science, University of Virginia, School of Computing, University of Georgia, Department of Radiation Oncology, Mayo Clinic, Institute of Western China Economic Research, Southwestern University of Finance and Economics

Abstract Preview: Purpose:
Traditional patient outcome analyses relied heavily on conventional statistical models that primarily elucidate correlation rather than causal relationships. In this study, we aim to ident...

A Comparative Analysis of Hand Calculations and Macro Monte Carlo Simulations for Electron Beam Dosimetry

Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr

Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado

Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...

A Diffusion-Based AI Framework for Continuous Deformable Image Registration and Time-Resolved Dynamic CT Generation

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Gregory Szalkowski, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Respiratory motion management is crucial for accurate radiation delivery to moving targets while protecting healthy tissue, relying on time-resolved volumetric imaging and continuous deformab...

A Monte Carlo Dosimetry-Based Cell Survival Model Incorporating Spatial and Temporal Heterogeneity for Rpt Preclinical Studies

Authors: Alejandro Bertolet, Michael D. Farwell, Sarah Gitto, Victor V. Onecha, Daniel Pryma, Aladdin Riad

Affiliation: Department of Pathology and Laboratory Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Department of Radiology, Perelman School of Medicine, Perelman School of Medicine at the University of Pennsylvania, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Responses to ionizing radiation (IR) strongly correlate with the absorbed dose. At the cellular level, this is typically described by a linear-quadratic relationship provided the cell populat...

A Novel Device for Radiation Therapy Machine Quality Assurance

Authors: Jonathan Dowell, Grace Francis, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Iridesce Solutions, Inc.

Abstract Preview: Purpose: A novel radiation therapy quality assurance (RT QA) device has been designed, constructed and tested. The nĂŒFilmTM machine QA system provides a method for collecting light, mechanical and rad...

AI-Driven Drug Discovery through an Interactive Analysis of Radiomics and Biological Insights in Glioblastoma

Authors: Nobuki Imano, Yuzuha Kadooka, Daisuke Kawahara, Misato Kishi, Yuji Murakami, Shumpei Onishi

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Neurosurgery, Hiroshima University Hospital

Abstract Preview: Purpose: Radiomics has proven useful in predicting overall survival in glioblastoma (GBM) patients, but consistent molecular correlations remain unidentified, leaving its biological basis unclear. Thi...

Adapting Newer Treatment Planning Strategy for Uveal Melanoma Cases Using Gamma Knife Radiosurgery

Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan

Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences

Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:

Analysis of Noise Power Spectra in MR Parallel Imaging

Authors: Sulaiman D. Aldoohan, Gerardo Garcia

Affiliation: University of Toledo Medical Center

Abstract Preview: Purpose: To evaluate the noise power spectra (NPS) of images acquired using parallel imaging with varying acceleration factors in 1-D and 3-D spaces and to compare the level of the power of the noise ...

Analyzer-Less X-Ray Interferometry with Super-Resolution Methods

Authors: Joyoni Dey, Hunter Cole Meyer, Murtuza Taqi

Affiliation: Louisiana State University

Abstract Preview: Purpose: We propose using super-resolution methods for X-ray grating interferometry without an analyzer with detectors that fail to meet the Nyquist sampling rate needed for traditional image recovery...

Application of the Lymphodose Framework to Brain Tumors: Unveiling the Prognostic Power of Circulating Lymphocyte Doses

Authors: Sophie Bockel, Eric Deutsch, Frederic Dhermain, Ibrahima Diallo, Anh Thu Le, Elaine Limkin, Pauline Maury, Charlotte Robert, Killian Sambourg, Camilla Satragno, Cristina Veres, François de Kermenguy

Affiliation: Gustave Roussy, Département de radiothérapie, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique

Abstract Preview: Purpose:
To study the correlation between the dose to circulating lymphocytes as evaluated by the LymphoDose framework and the incidence of severe radiation-induced lymphopenia (sRIL) in patients t...

BEST IN PHYSICS MULTI-DISCIPLINARY: Evaluation of Spot-Level N-12 PET Imaging for Online Range Verification in Multi-Field Intensity Modulated Proton Therapy

Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos

Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen

Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...

Characterizing an Osld Dosimetry System for Use in a Multi-Clinic Environment

Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé

Affiliation: Montefiore Medical Center

Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...

Combining Flat-Panel Imaging and Internal BB Markers for Precise HDR Brachytherapy Source Localization

Authors: Yibin Ling, Qihui Lyu, Ke Sheng

Affiliation: University of California Berkeley, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
High Dose Rate (HDR) brachytherapy enables radiation to concentrate on the tumor by sending the high-dose-rate radioactive source directly to the treatment site. On the other hand, the sha...

Commissioning, Validation and Pilot Study of New Rpld System for Dosimetry Audits in Bulgaria

Authors: Gueorgui Gueorguiev, Katia Sergieva, Filip Simeonov, Tsvetelina Todorova, Bozhidar Vladimirov

Affiliation: National Centre of Radiobiology and Radiation Protection, Queen Giovanna University Hospital

Abstract Preview: Purpose: Dosimetry audit is an essential tool enhancing confidence in the accuracy of treatment delivery and in prevention of radiation treatment incidents. Current work depicts how novel nationwide r...

Comparative Analysis of Nine Deep Learning Architectures for Variable Density Grappa 1H Magnetic Resonance Spectroscopy Imaging (MRSI) Reconstruction

Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang

Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center

Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...

Computed Tomography Organ Dose Library Derived from Newly Developed Newborn-Infant-Toddler Computational Phantoms

Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Adam Leon Kesner, Cameron B. Kofler, Juan Camilo Ocampo Ramos, Yitian Wang, Stefan Wehmeier

Affiliation: University of Chicago, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson

Abstract Preview: Purpose: To develop a slice-specific computed tomography (CT) organ dose library using Monte Carlo radiation transport simulations on a newly created set of newborn, infant, and toddler computational ...

Conversion Coefficients from Hp(10) to Organ and Effective Doses for Medical Staff Involved in Fluoroscopically Guided Interventional Procedures

Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller

Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration

Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...

Development of Patient-Specific Lead Ball Compensator for Total Body Irradiation

Authors: Chang Heon Choi, Minjae Choi, Yoonsuk Huh, Jin Jegal, Jung-in Kim, So-Yeon Park

Affiliation: Department of Radiation Oncology, Veterans Health Service Medical Center, Department of Radiation Oncology, Seoul National University Hospital

Abstract Preview: Purpose: Total Body Irradiation (TBI) aims to achieve a uniform dose distribution across the entire body. However, in conventional TBI setups that use extended source-to-surface distance (SSD) and lea...

Development of a Bayesian Network for a Comprehensive Uncertainty Assessment in Personalized Dosimetry after Targeted Radionuclide Therapy

Authors: NadÚge Anizan, David Broggio, Eric Chojnacki, Estelle Davesne, Didier Franck, Stéphanie Lamart, Alexandre Pignard

Affiliation: Institut Bergonié, Service de Physique Médicale, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSN-RES/SEMIA/LSMA

Abstract Preview: Purpose: To develop an innovative method enabling a comprehensive uncertainty budget associated to personalized absorbed doses for 177Lu-PSMA therapy and providing probability distributions of all dos...

Dysphagia Optimized Knowledge-Based Planning for Head and Neck Cancer

Authors: James E. Bates, Benjamin Hopkins, Kirk Luca, Shadab Momin, Justin R. Roper, Soumon Rudra, Eduard Schreibmann, Bill Stokes, Tu Thi, Xiaofeng Yang

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Swallowing dysfunctions after radiotherapy are caused by multiple factors yet are strongly associated with the irradiation of pharyngeal musculature due to its role in the initiation and comp...

Enhanced Prediction of Iroc Stereotactic Radiosurgery Phantom Audit Results with Treatment Parameters, Complexity Metrics, DVH, and Dosiomics Using Machine Learning

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Christine Peterson, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop predictive models for IROC SRS head phantom audits and to identify important factors influencing institutional performance.
Methods: The IROC SRS head phantom includes two TLDs ...

Extremity Imaging with Cone-Beam CT (CBCT) Scanner Dedicated for Hip Imaging – What Are the Effective Doses?

Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna

Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI

Abstract Preview: Purpose: To compute effective doses associated with imaging of the extremities with a HiRise (CurveBeam AI, Hatfield, PA) cone-beam CBCT scanner specifically designed for weight-bearing imaging of the...

Feasibility Study of Deep Learning-Based MRI-to-PET Generation for Rectal Cancer: Overall Survival Prediction and Pathological Complete Response Assessment

Authors: Weigang Hu, Zhenhao Li, Jiazhou Wang, Xiaojie Yin, Zhen Zhang

Affiliation: Fudan University Shanghai Cancer Center

Abstract Preview: Purpose:
This study aims to develop and validate a novel deep learning method to generate synthetic PET images for rectal cancer from MRI data. By incorporating metabolic information from the synth...

Feasibility Study of Single Gantry Angle Proton Minibeam Lattice Radiotherapy

Authors: Anthony Hong Cheol Lim, Rayyan L Mahmood, Alexander Stanforth, Chris C. Wang, Mingyao Zhu

Affiliation: Georgia Institute of Technology, Emory University

Abstract Preview: Purpose: The purpose of this project is to test the feasibility of proton minibeam lattice radiotherapy within an existing clinical setting.
Methods:
The TOPAS code is used to model a scenario i...

Field Output Correction Factors of Novel Shielded and Unshielded Silicon Diode Detectors

Authors: Mohamad Ahmad Alissa, Carson Brame, Damian Czarnecki, Olivier Evrard, Charbel A. Habib, Jeff Hildreth, Andy Murray, Andreas Schönfeld, Ann-Britt Schönfeld, David Towle, Gerd Wessing

Affiliation: CDT-West - Centrum fĂŒr Diagnostik und Therapie, Radiologie Vechta, Technische Hochschule Mittelhessen, MyMichigan Health, Sun Nuclear Corp., Mirion Technologies

Abstract Preview: Purpose: To characterize field output correction factors of novel shielded and unshielded silicon diode detectors.
Methods: Novel shielded and unshielded Silicon Diode Detectors (SDD) were characte...

Fractionation of Electron RT Reduces the Flash Effect in Murine Skin

Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel

Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison

Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...

Identification of Potential Patients for Resimulation and Adaptive Planning By Machine Learning

Authors: Mark Ashamalla, Renee Farrell, Jinkoo Kim, Kartik Mani, Xin Qian, Samuel Ryu, Yizhou Zhao

Affiliation: Stony Brook Medicine, Stony Brook University Hospital

Abstract Preview: Purpose: Adaptive planning is increasingly used in head and neck radiation therapy due to factors like tumor response or changes in patient anatomy. However, methods such as resimulation or offline re...

Image-Guided Adaptive Proton Therapy for Head and Neck Cancer Using a Novel Gantry-Less System

Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan

Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem

Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...

Imaging of Mn Washout in the Individual Welder Brain after Wearing Powered Air-Purifying Respirators (PAPRs)

Authors: Ulrike Dydak, Chia-Tien Hsu, Chang Geun Lee, Cora Mizimakoski, Humberto Monsivais, Jae Hong Park

Affiliation: Purdue University

Abstract Preview: Purpose: Overexposure to manganese (Mn) from inhaling welding fumes can lead to cognitive and motor deficits. We developed a whole-brain Mn-mapping approach to detect subtle but significant increases ...

Impact of IMRT Beam Scatter and Electronic Noise on Real-Time Kv and Fluoroscopy Image Quality

Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky

Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...

Implementing TG-191 for Robust Calibration of Scintillation Imaging As a Clinical dosimetry Tool

Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose: Scintillation imaging has demonstrated unique advantages to existing clinical in vivo dosimetry (IVD) techniques by enabling full-field visualization, direct comparison to the treatment plan,...

Improving Operational Efficiency in Head and Neck Proton Therapy through Adaptation Analysis

Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey

Affiliation: Thompson Proton Center

Abstract Preview: Purpose: Proton therapy plans can be highly sensitive to both anatomical changes and positional errors, making the acquisition of Quality Assurance CT (QACT) images a routine clinical practice during ...

Initial Three-Year Machine Performance Assessment of a Superficial Radiation Therapy Unit

Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...

Innovative Biological Adaptive Radiotherapy (BART) Approach for Head-and-Neck Cancer Treatment Interruptions

Authors: Nobuki Imano, Daisuke Kawahara, Akito S Koganezawa, Yuji Murakami, Ikuno Nishibuchi, Takuya Wada

Affiliation: Department of Information and Electronic Engineering, Faculty of Science and Engineering, Teikyo University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University

Abstract Preview: Purpose: Adaptive radiotherapy (ART) compensates for treatment plans based on anatomical changes while not considering biological effects such as interruptions during treatment. This study aims to dev...

Innovative in-Silico Modeling for Timing Immunotherapy in Radiotherapy-Combined Treatments

Authors: Daisuke Kawahara, Yoichi Watanabe

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School

Abstract Preview: Purpose: Combination therapies with immunotherapy (IT) and radiotherapy (RT) are widely used, but the optimal IT timing is unclear. This study leverages a computational cellular automaton (CA) model, ...

Investigating Factors Impacting the Consistency of Signal-to-Noise Ratio in Mammographic Automatic Exposure Control

Authors: James Ward, Anzi Zhao

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: This study investigates the impact of tissue-equivalent attenuator materials, the region of interest (ROI) size, and the orientation of the attenuator positioning on the measured signal-to-no...

Investigation and Machine-Learning Modeling of Dosimetric Discrepancies in Eclipse-Calculated Head and Neck Treatment Plans

Authors: Andres Portocarrero Bonifaz, Ian Schreiber

Affiliation: CARTI Cancer Center

Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...

Investigation of Treatment Planning System (TPS) Algorithms for Helical Tomotherapy Total Body Irradiation (TBI)

Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders

Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health

Abstract Preview: Purpose: This study involved the use of Accuray’s TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accuray’s Radixact machine, and dose calculation algorithm, do...

Investigation of the Impact of Dlg Changes on Plan Quality and Patient Specific QA

Authors: Nicole C. Detorie, Steven M. Kirsner, Remy Y. Manigold

Affiliation: Scripps Cancer Center

Abstract Preview: Purpose:
Dosimetric Leaf Gap (DLG) is an important factor in obtaining the proper beam model in the Eclipse treatment planning system. The purpose of this study was to investigate the dosimetric im...

Knowledge-Informed Deep Learning for Accurate and Interpretable Extracapsular Extension Detection in Head and Neck Squamous Cell Carcinoma

Authors: William N. Duggar, Amirhossein Eskorouchi, Haifeng Wang

Affiliation: Mississippi State University, University of Mississippi Medical Center

Abstract Preview: Purpose:
Extracapsular extension (ECE) in lymph nodes represents a critical prognostic factor in head and neck squamous cell carcinoma (HNSCC), bearing important implications for staging, treatment...

Lesion Detection in Contrast Enhanced Cone Beam Breast CT with a Photon Counting Detector: A Monte Carlo Study

Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University

Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...

Mid-Range Planning for Efficient and Robust Proton Arc Therapy

Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...

Multi-Institutional Analysis of CT Dose Index Variability and Radiomics Features

Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati

Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...

On Estimating Effective Doses Associated with Different Imaging Protocols for Weight-Bearing Imaging of the Hip with a Dedicated Cone Beam CT (CBCT) Scanner

Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna

Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI

Abstract Preview: Purpose: To estimate effective doses associated with different imaging protocols for hip imaging with a cone beam CT (CBCT) scanner specifically designed for weight-bearing acquisitions.
Methods: A...

Predicting CBCT-Based Adaptive Radiation Therapy Session Duration Using Machine Learning

Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri

Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego

Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patients’ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...

Predicting Proton Therapy Dose Delivery Accuracy: A Machine Learning Approach Using Iroc’s Proton Phantom Data

Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROC’s proton phantom program.
Methods: IROC’s proton QA program has six proton...

Predicting and Monitoring Response to Head and Neck Cancer Radiotherapy Using Multi-Modality Imaging and Radiobiological Digital Twin Simulations

Authors: Eric Aliotta, Michalis Aristophanous, Joseph O. Deasy, Bill Diplas, Milan Grkovski, James Han, Vaios Hatzoglou, Jeho Jeong, Nancy Y Lee, Ramesh Paudyal, Nadeem Riaz, Heiko Schoder, Amita Shukla-Dave

Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To forecast radiotherapy treatment response for head and neck cancer (HNC) using multimodality imaging and personalized radiobiological modeling.
Methods: Multi-modality imaging data from ...

Prediction of Head and Neck Cancer Using Artificial Neural Network through Basic Health Data

Authors: Abdullah Hidayat, Wazir Muhammad

Affiliation: Florida Atlantic University

Abstract Preview: Purpose: This study aims to predict Head and Neck cancer using an artificial neural network (ANN) through readily available basic health data. The goal is to uncover hidden patterns and predictors in ...

Protocol for In Vivo Dosimetry Using Myoslchip System: Characterization and Clinical Application

Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park

Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School

Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...

Real-Time Output Gating and Fault Handling for an Uhdr Mobetron

Authors: Petr Bruza, David J. Gladstone, Lesley A Jarvis, Austin Sloop, Kevin J. Willy, Rongxiao Zhang

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose:
Active beam monitoring and output-gated dosimetry are essential systems for safe and accurate radiation delivery. UHDR irradiators such as the Mobetron rely on pre-programmed regimes and t...

Reasoning-Driven Prompts Improve EHR-Based Outcome Prediction and Clinical Interpretability in Large Language Models

Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas

Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco, University of San Francisco

Abstract Preview: Purpose: As Large Language Models (LLMs) continue to evolve, their ability to analyze Electronic Health Record (EHR) notes for clinical decision support expands. Chain of Thought (COT) reasoning, an e...

Reconstructing Radiopharmaceutical Distributions Using Coded Aperture Tomography with Photon Counting Detector

Authors: David P. Adam, Xun Jia, Youfang Lai, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: Radiopharmaceutical therapy is experiencing a resurgence in interest due to its potential of treating widespread metastatic disease in a patient-specific manner. Accurately measuring and desc...

Simulation Design of a Dedicated Head Coil for Enhanced EPT Imaging to Map the Electrical Properties of Tumor Tissues

Authors: Jingyao Chen, Yingli Yang, Jie Zhang

Affiliation: Department of Radiology, Ruijin Hospital, Shanghai Ruijin Hospital, Shanghai United imaging Healthcare Advanced Technology Research Institute

Abstract Preview: Purpose: Magnetic Resonance Electrical Properties Tomography (MR EPT) is a method to spatially mapping the conductivity and permittivity based on small B1 field changes after the imaged object was int...

Spatially Aware Radiomics Integrating Anatomical Knowledge to Improve Lymph Node Malignancy Prediction in Head and Neck Cancer

Authors: Liyuan Chen, Sepeadeh Radpour, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Accurate lymph node malignancy prediction is pivotal in optimizing radiation treatment strategies for head and neck (HN) cancer patients. While conventional radiomics models leverage intensit...

Streamlined Stereotactic Radiosurgery (SRS) Commissioning Experience with a 6FFF Beam for an Elekta Versa: A Clinical Overview for Increased Precision.

Authors: Asma Amjad, Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Accurate and precise linac-based SRS commissioning can be very challenging. Thus, it is important to increase the confidence in the measurement at each step prior to end-to-end testing. The p...

Testing Experience in Dose Monitoring Solutions: Automation Aberrations in Automated Organ Dose Estimation

Authors: Lawrence T. Dauer, Yusuf Emre Erdi, Yiming Gao, Dustin W. Lynch, Usman Mahmood

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Radiation dose to patients in CT examinations (CTDIvol, DLP) is tracked in dose monitoring solutions. Some solutions push for automatically estimating patient organ doses based on exam images...

Two Radiochemical Monte Carlo Models to Investigate the Radical Yields Under Proton Flash Irradiations

Authors: Yujie Chi, Yao Hao, Xun Jia, Youfang Lai, Yuting Peng, Francisco Javier Reynoso, Lingshu Yin, Tianyu Zhao, Xiandong Zhao

Affiliation: Johns Hopkins University, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Physics, University of Texas at Arlington, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, University of South Florida

Abstract Preview: Purpose: FLASH radiation therapy has shown remarkable tissue sparing effects compared to radiation therapy at conventional dose rates (CDR). Yet, its mechanism remains unclear. Radical production modu...

Using a-Si 1200 Epid Portal Dosimetry for VMAT Commissioning

Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed

Affiliation: Bay Pines VA Medical Center

Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...

Validation of 3D Pseudo-Dose Map Reconstructed from Multi-View Cherenkov Images in Total Skin Electron Therapy

Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison

Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...

“See” through Surface: Transforming Surface Imaging into a Real-Time Three-Dimensional Imaging Solution for Intra-Treatment Image Guidance

Authors: Steve B. Jiang, Ruiqi Li, Hua-Chieh Shao, Kenneth Westover, You Zhang, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Respiratory motion is a long-standing challenge for lung SBRT, particularly for centrally-located lung tumors where increased toxicity demands more precise motion management during treatme...