Authors: Jeremy T. Booth, Nicholas Hardcastle, Freeman Jin, Alicja Kaczynska, Paul J. Keall, Chandrima Sengupta
Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, Physical Sciences, Peter MacCallum Cancer Centre, Image X Institute, Faculty of Medicine and Health, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: An ESTRO survey reported that 71% of radiotherapy centers across 41 countries want to implement real-time image guided radiation therapy (IGRT) to improve patient outcomes. To address this gl...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...
Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo
Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...
Authors: Dukagjin Blakaj, Zhilin Hu, Stephen Kang, Abberly Lott Limbach, Lanchun Lu, Henry Xiang, Jie Zhang
Affiliation: Pharostek, Department of Pediatrics, The Ohio State University, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiology, University of Kentucky, Department of Pathology, The Ohio State University, Department of Radiation Oncology, The Ohio State University, Department of Otolaryngology, The Ohio State University
Abstract Preview: Purpose: Detect surgical margin in vivo using an original barcode-reading type portable OCT imaging system.
Methods: We developed a barcode-reading type portable optical coherence tomography (OCT) ...
Authors: Somayeh Gholami, Saeedeh Ketabi, Jeremy Kunz, Ali Yousefi
Affiliation: Department of Radiation Oncology, University of Utah, University of Utah, Department of Management- Operations Research, University of Isfahan
Abstract Preview: Purpose: This paper aims to present a novel approach for automatic knowledge-based planning optimization for Intensity Modulated Radiotherapy, along with the two downsizing techniques for improving th...
Authors: Girish Bal, Ke Colin Huang, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue
Affiliation: Purdue University, RefleXion Medical, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) uses real-time positron emission tomography (PET) signals to precisely direct radiotherapy beamlets. The success of BgRT planning and delivery relies on PET...
Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa
Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...
Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer
Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...
Authors: Sung Hwan Ahn, Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, Hyeongjin Lim, Sang Yoon PARK, Myonggeun Yoon
Affiliation: Institute of Global Health Technology (IGHT), Korea University, Republic of Korea, Korea University, Samsung Medical Center
Abstract Preview: Purpose:
This study aims to evaluate the feasibility of real-time monitoring of conductivity changes induced by thermal variations during tumor treating fields (TTFields) therapy using Electrical I...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...
Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...
Authors: Angela J Da Silva, Andrew Groll, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: PET-based biology-guided radiotherapy (BgRT) is a radiation therapy technique that uses PET imaging to deliver tracked dose to the tumor in real-time. We characterized the delivery accuracy o...
Authors: Youssef Ben Bouchta, Chen Cheng, Owen Thomas Dillon, Mark Gardner, Paul J. Keall, Purnima Sundaresan
Affiliation: Radiation Oncology Network, Western Sydney Local Health District, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: There are three clinical motivations for real time IGRT in head and neck cancer radiation therapy: (1)50% of patients experience anxiety from the patient mask (2)patient motion still occurs d...
Authors: Neal Andruska, Lianna D. DiMaso-Myers
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To provide details on how our clinic assesses respiratory motion during treatment of a pancreatic adenocarcinoma during dose escalated radiation therapy on a linear accelerator with the aid o...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patients’ setups. MAHR complements current image-guidance...
Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...
Authors: Usha Robins Abraham, Monique Lockhart Chisem, Alonso N. Gutierrez, Janos Juhasz, Michael Leyva, Carlos M. Rivera, Ranjini P. Tolakanahalli, Vanessa Vega Fleites
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose:
Accurate breath hold (BH) gated treatments rely heavily on patient cooperation. Maintaining consistent breath-hold levels can be challenging for patients. Surface image guidance (SGRT) is ...
Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone
Affiliation: Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Cherenkov images are two-dimensional projections of the surface light emissions, and lack spatial information about the radiotherapy beam delivery. We implement the first fusion of Cherenkov ...
Authors: D. Michael Lovelock, Charlotte Elizabeth Read, Ren-Dih Sheu, Jing Wang, Tingyu Wang
Affiliation: Icahn School of Medicine at Mount Sinai, Jersey Shore University Medical Center
Abstract Preview: Purpose:
Early Eclipse models use rectangular fluence profiles (widened by the dosimetric leaf gap (DLG) to account for the fact that leaf tips are rounded). Eclipse Version 18 (V18) uses enhanced ...
Authors: Daisuke Kawahara, Takaaki Matsuura, Yuji Murakami, Ryunosuke Yanagida
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima
Abstract Preview: Purpose: In recent years, automation in radiation therapy planning using AI has gained significant attention to reduce the workload of treatment planners. Adaptive Radiation Therapy (ART), as a new fo...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba
Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center
Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...