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Results for "reconstruction algorithms": 58 found

3D Image Quality Evaluation of a New CT Scanner Employing 3D Landmark Scans, Super Resolution Reconstruction, and Ag Beam Filtration

Authors: Ishika Bhaumik, John M. Boone, Michael T Corwin, Eric S Diaz, Ahmadreza Ghasemiesfe, Andrew M. Hernandez, Sarah E. McKenney, Misagh Piran, Ali Uneri, Eric L White

Affiliation: UC Davis, UC Davis Health, University of California, Johns Hopkins Univ

Abstract Preview: Purpose: A new model CT scanner (Canon Aquilion One Insight) was recently installed at our institution, and it included a 3D Landmark (3DLM) scan for automatic scan planning, a new deep learning recon...

4D CBCT Dynamic Images Recovery Using a 4D Neural Network

Authors: Ziheng Deng, Yao Hao, Runping Hou, Deshan Yang, Jun Zhao, Yufu Zhou

Affiliation: Department of Radiation Oncology, Duke University, School of Biomedical Engineering, Shanghai Jiao Tong University, Washington University School of Medicine, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: 4D CBCT has been developed to provide dynamic images for image-guided radiation therapy. However, as projection data are sorted into sparse and clustered phase-specific bins, 4D CBCT images a...

A Dual Energy CT-Guided Intelligent Radiation Therapy Platform

Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...

A Novel 2D Scintillation Dosimeter Using Long Scintillating Fibers.

Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan

Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval

Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...

A Quantitative Analysis of Hypersight CBCT Image Quality Using a Phantom-Based Approach Under Different Scatter Conditions

Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC

Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...

A Real-Time Framework for Fiducial Tracking and Intrafraction Motion Assessment of Cyberknife in Stereotactic Body Radiation Therapy for Liver Cancer

Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao

Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...

A Single-View-Based Electroacoustic Tomography Imaging Using Deep Learning for Electroporation Monitoring

Authors: Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu, Jie Zhang

Affiliation: University of Maryland School of Medicine, University of California, Irvine

Abstract Preview: Purpose: To achieve the full-view image from a single-view sinogram using a two-stage deep learning model for electroacoustic-tomography (EAT), which is an emerging imaging technique with significant ...

Advancing Deep Segmentation Accuracy in CBCT for Radiotherapy Via Robust Scatter Mitigation: First Results from a Pilot Trial

Authors: Cem Altunbas, Farhang Bayat, Roy Bliley, Rupesh Dotel, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi

Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic, University of Colorado Anschutz Medical Campus

Abstract Preview: Purpose: Automatic segmentation of anatomical structures in CBCT images is key to enabling dose delivery monitoring and online plan modifications in radiotherapy. However, poor image quality can degra...

Advancing Ionizing Radiation Acoustic Imaging: A Deep Learning Approach for Denoising and Quantitative Reconstruction

Authors: Kyle Cuneo, Issam M. El Naqa, Dale W. Litzenberg, Yiming Liu, Xueding Wang, Lise Wei, Wei Zhang, Jiaren Zou

Affiliation: University of Michigan, H. Lee Moffitt Cancer Center

Abstract Preview: Purpose: To quantitatively map 3D dose deposition during radiotherapy, empowering real-time adaptive radiation treatment.

Methods: The research features reconstructing dose deposition from acou...

Analyzer-Less X-Ray Interferometry with Super-Resolution Methods

Authors: Joyoni Dey, Hunter Cole Meyer, Murtuza Taqi

Affiliation: Louisiana State University

Abstract Preview: Purpose: We propose using super-resolution methods for X-ray grating interferometry without an analyzer with detectors that fail to meet the Nyquist sampling rate needed for traditional image recovery...

Assessing Dose Enhancement and Shadowing Effects in Head and Neck Cases with Titanium Mandibular Implants

Authors: Sarah A. Ashmeg, Travis James McCaw, Joseph Shields, Matthew Spector, Christopher Tyerech, Christopher T Wilke

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, Department of Radiation Oncology, University of Pennsylvania, UPMC

Abstract Preview: Purpose: Patients with oral cavity cancer often undergo surgical extirpation prior to radiation, and surgical implants are utilized to reconstruct the resulting defect. This study dosimetrically evalu...

Assessment of the Impact of CT Respiratory Motion on PET SUV Quantification through Virtual Imaging

Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei

Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington

Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...

BEST IN PHYSICS ULTRASOUND: A Calibration Framework for Quantifying Element Misalignment in 2D Matrix Array Transducers Used in 3D Quantitative Ultrasound

Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez

Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison

Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...

Backward Photon Monte Carlo Propagator (BPMCP): Proof of Concept of a Fully Physics-Driven SPECT Reconstruction

Authors: Alejandro Bertolet, Carlos Huesa-Berral, Victor V. Onecha

Affiliation: Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Radioembolization for liver tumors using 90Y microspheres uses SPECT as confirmatory dosimetry, although 90Y is a pure β-emitter, and SPECT-imaging is only available through subsequent bremss...

CNN-Based Reconstruction for 3D Scintillation Dosimetry of Proton Pencil Beams

Authors: Sam Beddar, Jason Michael Holmes, Daniel G. Robertson, James J. Sohn, Ethan D. Stolen

Affiliation: Department of Radiation Oncology, Mayo Clinic, MD Anderson Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago

Abstract Preview: Purpose: Camera-based scintillation dosimetry incorporating large volumes have shown promise for fast and comprehensive evaluation of external beam treatment fields. While some efforts have been made ...

Commissioning Radcalc v7.3 with a Collapsed Cone Calculation Algorithm for 6X FFF and 10X FFF Energies

Authors: Maria Jose Almada, Carlos Bohorquez, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger

Affiliation: LAP, Instituto Zunino - Fundacion Marie Curie

Abstract Preview: Purpose:
PSQA is crucial in maintaining patient safety, typically depending on dosimetric measurements. However, advancements in computational technology have highlighted the growing significance o...

Comparing SPECT Dose Reconstruction Algorithm Accuracy As a Function of Imaging Parameters

Authors: Srinivas Cheenu Kappadath, Brian Michael Kelley, Benjamin P. Lopez

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Imaging systems are subject to errors from finite spatial resolution and voxel size. This work demonstrates their effect on dose algorithm {Monte Carlo (MC), dose-volume kernel (DVK), and ...

Comparison of CBCT Dose Calculation Accuracy between Truebeam Hypersight Image Reconstruction Algorithms

Authors: Sarah Aubert, Harald Keller, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...

Comparison of Respiratory Motion between 4D-MR and 4D-CT in Compression Belt Patients

Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis, Hamlet Spears

Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: This study evaluates the range of motion of abdominal organs using 4D stack-of-stars magnetic resonance (MR) imaging and 4D computed tomography (CT), the current clinical standard. Accurate o...

Deep Learning-Based Prompt Gamma Imaging for Proton Range Verification Using Patient Data Simulation

Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma

Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC

Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...

Determining the Optimal CT Tube Voltage for Imaging Bone Structures in Radiotherapy.

Authors: Mohamed Bahaaeldin Mohamed Afifi, Nahla Nagy Ahmad Ataalla, Ahmed A. Eldib

Affiliation: Fox Chase Cancer Center, Radiological Sciences and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University.

Abstract Preview: Purpose: Optimizing CT imaging parameters is crucial for balancing radiation dose, contrast resolution, and accurate Hounsfield unit representation, particularly in radiotherapy treatment planning. Th...

Development of Sphere Phantoms for Quantitative Evaluation of Computed Tomography Systems Resolution

Authors: Hyo-Min Cho, Changwoo Lee

Affiliation: Korea Research Institute of Standards and Science

Abstract Preview: Purpose: We develop sphere phantoms to assess spatial resolution of computed tomography (CT) systems and validate its usability using table-top X-ray experiment systems.
Methods: We manufactured sp...

Development of a Proton CT System Based on 2D Scintillation Detection

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: To develop a proton CT system using scintillator-based 2D dose distribution detection for accurate proton imaging.
Methods: The proposed proton CT system consists of a brass collimator wit...

Development of a Quantitative Surface Mapping Analysis Framework Involving a Robust Mask Removal Algorithm for Improved Objective Patient Setup Assessment in Head and Neck Intensity Modulated Proton Therapy

Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Michael H. Shang, Stephen Shang, Timothy R Williams

Affiliation: South Florida Proton Therapy Institute, SFPRF, Department of Radiation Medicine, MedStar Georgetown University Hospital

Abstract Preview: Purpose:
Daily image guidance for head and neck intensity-modulated proton therapy (IMPT) presents significant challenges due to large target volumes and anatomical changes. Geometric deviations al...

Dose Reconstruction from Prompt-Gamma Imaging Towards Real-Time Adaptive Proton Therapy

Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie

Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-Universität (LMU) München

Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...

Dual-Domain Reconstruction Network for Nonstop Gated CBCT Imaging: Application in Respiratory Gating Ablative Radiotherapy for Pancreatic Cancer

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yabo Fu, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Boris Mueller, Huiqiao Xie, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gating ablative radiotherapy for pancreatic cancer accounts for tumor movement due to respiration and typically requires 5, 15, or 25 fractions. Pretreatment imaging verification is essential...

Dynamic X-Ray Acoustic Computed Tomography (XACT)

Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan

Affiliation: University of California, Irvine

Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...

Evaluating the Capabilities of Hypersight CBCT for Advanced Dual-Energy CBCT Imaging in Online Adaptive Radiotherapy

Authors: Yi-Fang Wang, Yading Yuan

Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center

Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...

Evaluating the Impact of Reconstruction Algorithm on Wide-Angle Digital Breast Tomosynthesis System Optimization for Microcalcification Detection

Authors: Xiaoyu Duan, Xinyu Hu, Runqiu Li, Xiang Li

Affiliation: Dukekunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
Accurate detection of small-sized microcalcifications (μCalcs) (< 500 µm) is critical for early breast cancer diagnosis, requiring optimal imaging systems and reconstruction algorithms. Ho...

Evaluation of Hypersight CBCT Scanning Techniques for Motion Management in Online Adaptive Radiotherapy: A Comparative Study of Slow, Fast, and Averaged Scans

Authors: Fan Liu, Adam C. Riegel, Yi-Fang Wang

Affiliation: Columbia University Irving Medical Center

Abstract Preview: Purpose: HyperSight, Varian Medical Systems' latest CBCT technology, integrates rapid 6-second data acquisition with advanced iterative reconstruction, enabling precise real-time contouring and dose c...

Evaluation of a Commercial Metal Artifact Reduction Algorithm for IGRT in Patients with Hip Prostheses

Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson

Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison

Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...

First In Vivo Proton Beam Irradiation of Mice with Quasi-Real-Time Range Verification with the Sirmio PET Scanner

Authors: Niels Bassler, Jonathan Bortfeldt, Francesco Evangelista, Giulio Lovatti, Jasper Nijkamp, Rasmus Nilsson, Munetaka Nitta, Katia Parodi, Marco Pinto, Per R. Poulsen, Brita Singers Sørensen, Peter Thirolf, Erik Traneus, Taiga Yamaya

Affiliation: RaySearch Laboratories AB, National Institutes for Quantum Science and Technology, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: Within the SIRMIO project (Small Animal Proton Irradiator for Research in Molecular Image-Guided Radiation Oncology), we aimed to perform the first in vivo proton beam treatment with a dedica...

Hybrid Prior-Enhanced Deep Image Prior (HPEDIP) Image Reconstruction for Ultra-Short Scans

Authors: Renee Farrell, Jinkoo Kim, Xin Qian, Ziyu Shu, Zhaozheng Yin, Tiezhi Zhang

Affiliation: Stony Brook Medicine, Washington University in St. Louis, Stony Brook University, Stony Brook University Hospital

Abstract Preview: Purpose: Ultra-short CT scan allows fast imaging speed, dose reduction, and compact system design. We developed a deep image prior (DIP) based reconstruction method named Hybrid Prior-Enhanced Deep Im...

Impact of Computed Tomography Noise Reference Levels in a Pediatric Hospital

Authors: Samuel L. Brady, Joseph G. Meier

Affiliation: Cincinnati Childrens Hospital Med Ctr

Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...

Improvements from Monte Carlo Simulations over Pencil Beam Algorithms for Normal Tissue Dose Reconstruction in Proton Therapy Patients

Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock

Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research

Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...

Improving Quantitative Accuracy of Maximum-a-Posteriori Expectation Maximization Reconstruction By Optimizing Gibbs Prior Parameters in SPECT

Authors: Krishnendu Saha

Affiliation: Cleveland Clinic Foundation

Abstract Preview: Purpose: The goal is to improve quantitative accuracy of a Maximum-a-posteriori expectation maximization (MAPEM) reconstruction of SPECT phantom images by optimizing Gibbs prior parameters.
Methods...

In silico Evaluation Vs Standard Phantom Evaluation of a Deep Learning Reconstruction Algorithm

Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Dylan Mather, Akira Nishikori, Daniel W Shin

Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA

Abstract Preview: Purpose: To validate the performance a deep learning reconstruction (DLR) algorithm in an anatomical background compared to a uniform phantom background.
Methods: An analytic forward projection mod...

In-Vivo Image Quality of Head/Neck and CNS with an Advanced C-Arm Linac CBCT Solution

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...

Integrating SPECT and Compton Imaging for Multi-Energy Photon Reconstruction

Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu

Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...

Inverse Geometry Photon Counting CBCT

Authors: Saree Alnaghy, Owen Thomas Dillon, Sean P Hood, Paul J. Keall, Ricky O'Brien, Tess Reynolds

Affiliation: Image X Institute, Faculty of Medicine and Health, The University of Sydney, University of Wollongong, Medical Radiations, School of Health and Biomedical Sciences, RMIT University

Abstract Preview: Purpose: Photon Counting Detectors (PCDs) have been demonstrated to improve resolution, contrast and lesion detectability in fan-beam CT. There is naturally a desire to bring these improvements to Con...

Investigating Microcalcification Detectability in a Static Breast Cone Beam CT Via Monte Carlo Simulation

Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University

Abstract Preview: Purpose: Gantry motion and patient breathing during a breast cone beam CT (bCBCT) scan is one of the major challenges for microcalcification (μCalcs) detection. By deploying a large number of individu...

Investigation of Prompt Gamma Imaging Using a Three Axis Rotating Compton Camera

Authors: Molokotima Kekana, Dennis S. Mackin, Stephen W. Peterson, Jerimy C. Polf

Affiliation: Department of Physics, University of Cape Town, M3D, Inc, The University of Texas MD Anderson Cancer Center, Houston

Abstract Preview: Purpose: To study the imaging characteristics of a prototype prompt gamma (PG) imaging system consisting of multiple rotating Compton cameras (CC).

Methods: The prototype CC imaging system is c...

Latent Diffusion for 3D CT Reconstruction from Biplanar X-Rays

Authors: Guha Balakrishnan, Osama R. Mawlawi, Yiran Sun, Ashok Veeraraghavan

Affiliation: RICE University, UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Previous deep learning (DL) techniques such as X2CT-GAN [1] has shown great promise in reconstructing realistic CT volume from biplanar X-rays, however they introduce numerous artifacts in...

Leveraging Photon Counting Detector CT and Advance Reconstructions to Improve the Accuracy of Vessel Tracing in Prostate Artery Embolization

Authors: Christopher P. Favazza, Andrea Ferrero, Taylor Froelich, Forrest Linch, Scott Thompson

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Photon counting detector (PCD) CT is a promising tool to enhance pre-procedural planning and intra-procedural guidance for prostate artery embolization due to its unsurpassed ultra-high spati...

Multi-Institutional Analysis of CT Dose Index Variability and Radiomics Features

Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati

Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...

Optimizing Low-Dose Imaging Parameters for Dual-Energy Cone-Beam Computed Tomography in Image-Guided Radiation Therapy

Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske

Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...

Physics-Informed Neural Network for In Vivo Dosimetry during Proton Therapy Using Protoacoustic Tomography

Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center

Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...

Prior-Adapted Progressive Motion-Resolved CBCT Reconstruction Using a Dynamic Reconstruction and Motion Estimation Method

Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...

Shape-Optimized Radiation-Induced Acoustic Computed Tomography for In Vivo online Monitoring of Radiation Therapy

Authors: Yong Chen, Gilberto Gonzalez, Omprakash Gottam, Liangzhong Xiang

Affiliation: University of California, Irvine, Koneru Lakshmaiah Education Foundation, University of Texas at San Antonio., University of Oklahoma Health Science Center

Abstract Preview: Purpose: Clinics currently lack techniques for real-time, in vivo monitoring of radiation therapy (RT), which is desirable for precise treatment. Radiation-induced acoustic computed tomography (RACT) ...

Simulation Design of a Dedicated Head Coil for Enhanced EPT Imaging to Map the Electrical Properties of Tumor Tissues

Authors: Jingyao Chen, Yingli Yang, Jie Zhang

Affiliation: Department of Radiology, Ruijin Hospital, Shanghai Ruijin Hospital, Shanghai United imaging Healthcare Advanced Technology Research Institute

Abstract Preview: Purpose: Magnetic Resonance Electrical Properties Tomography (MR EPT) is a method to spatially mapping the conductivity and permittivity based on small B1 field changes after the imaged object was int...

Speckle Image-Based Point Spread Function Reconstruction in Clinical Diagnostic X-Ray Systems

Authors: Jonthomas Michael Box, Isaac B. Rutel

Affiliation: University of Oklahoma Health Sciences Center

Abstract Preview: Purpose: This study assesses the feasibility of using speckle images and a modified phase retrieval algorithm to reconstruct the point spread function (PSF) of a diagnostic x-ray system. While speckle...

Surface Mapping of Couch Kick Cherenkov Images for Rotation-Independent Treatment Verification in External Beam Radiotherapy

Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone, Lesley A Jarvis, Allison Matous

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose: During external beam radiation therapy, couch kicks are often necessary to achieve effective treatments, yet they make interpreting Cherenkov images much more challenging. We present a surfac...

Technique Factors Optimization and Radiation Dosimetry of an Upright, Short-Scan, Cone-Beam, Dedicated Breast CT System

Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu

Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center

Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...

Three-Dimensional Reconstruction of Triggered Images with Dehazing Algorithm for Precise Intrafraction Motion Detection in Spine SBRT

Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University

Abstract Preview: Purpose: To precisely detect intrafraction patient motion during spine stereotactic body radiotherapy (SBRT) treatment delivery, we propose an optimized technique for three-dimensional reconstruction ...

Time-Resolved CBCT: A Novel Solution for Motion Management

Authors: Bulent Aydogan, Xiaochuan Pan, Erik Pearson, Zheng Zhang

Affiliation: The University of Chicago

Abstract Preview: Purpose: Motion management remains one of the significant challenges in external beam radiation therapy (RT). We are developing time-resolved cone-beam computed tomography (trCBCT) for imaging during ...

Ultra-Sparse-View Cone-Beam CT Reconstruction Based Strictly-Structure-Preserved Deep Neural Network in Image-Guided Radiation Therapy

Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang

Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University

Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...

Validation of a Simulation Tool and in-Silico Assessment of Low Contrast Detectability for Super-Resolution Deep Learning Reconstruction

Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Akira Nishikori, Daniel W Shin

Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA

Abstract Preview: Purpose: To validate a simulation tool using physics-based image quality metrics in both phantom and patient data, and to assess the low contrast detectability (LCD) of Super Resolution-Deep Learning ...

X-Ray Motion Tomography: Creating 3D Lung Motion from Sparse 2D X-Ray Projections

Authors: Hilary Louisa Byrne, Owen Thomas Dillon, Paul J. Keall, Hunor Kertesz, Ricky O'Brien, Tess Reynolds

Affiliation: University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney, Medical Radiations, School of Health and Biomedical Sciences, RMIT University

Abstract Preview: Purpose: Imaging of lung motion and function has typically required multiple volumetric CT images to create deformation vector fields (DVF) for motion and ventilation images (function). However, CT sc...