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Results for "region focused": 14 found

A Quantitative, Predictable Guided Optimization Approach for Eclipse to Mitigate the SRS “Ring of Fire”

Authors: Ivan L. Cordrey, Dharmin D. Desai

Affiliation: Cumberland Medical Center - Cancer Center, Varian Advanced Oncology Solutions

Abstract Preview: Purpose: For larger PTVs, VMAT optimizations performed within Eclipse often generate SRS plans with widely scattered hotspots distributed around the inner edge of the PTV – the “ring of fire.” This pr...

Addressing Missing MRI Sequences: A DL-Based Region-Focused Multi-Sequence Framework for Synthetic Image Generation

Authors: Amir Abdollahi, Oliver Jäkel, Maxmillian Knoll, Rakshana Murugan, Adithya Raman, Patrick Salome

Affiliation: UKHD & DKFZ, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), German Cancer Research Centre(DKFZ), DKFZ, MGH

Abstract Preview: Purpose:
Missing MRI sequences, due to technical issues in data handling or clinical constraints like contrast agent intolerance, limit the use of medical imaging datasets in computational analysis...

Advanced Skeletal Models for Icrp Reference Pediatric Individuals: Development and Dosimetric Implications

Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Bangho Shin, Yitian Wang

Affiliation: University of Florida

Abstract Preview: Purpose: The skeleton plays a critical role in dosimetry, containing red bone marrow (RBM) and bone endosteum (BE), which are closely linked to radiation-induced leukemia and bone cancer. While severa...

Assessment of Vasculature Mapping Using Infrared Imaging System for Treatment Planning

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan

Affiliation: The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital

Abstract Preview: Purpose: The response of healthy vasculature due to radiation treatments is an underexplored area of radiation oncology. Understanding the impact of radiation on veins could advance treatment optimiza...

Attention-Based Multiple Instance Learning of Head and Neck Cancer Grading on Digital Pathology Using Vision-Language Foundational Models

Authors: Kyle J. Lafata, Xiang Li, Megan K. Russ, Zion Sheng

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System

Abstract Preview: Purpose: To adapt Vision-Language Foundational Models (VLFM) to perform HNSCC tumor grading on H&E whole slide images (WSI) via attention-based multiple instance learning (ABMIL).
Methods: We utili...

CBCT and Exactrac Dynamic Agreement for Patient Positioning during Spine SRS/SBRT Treatments

Authors: Martha J. Malin, Matthew Schelin

Affiliation: NYU Langone Health

Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.

Deep Learning-Based Auto-Segmentation in Cervical High-Dose-Rate Brachytherapy with Clinical Considerations

Authors: Benjamin Haibe-Kains, Ruiyan Ni, Alexandra Rink

Affiliation: Department of Medical Biophysics, University of Toronto, University Health Network

Abstract Preview: Purpose: Accurate auto-segmentation for targets and organs-at-risk (OARs) using deep learning reduces the delineating time in radiotherapy. In high-dose-rate brachytherapy, specific clinical criteria ...

Deep Learning-Based Denoising for Template Matching in Real-Time Tumor Tracking Using Kv Scattered X-Ray Imaging

Authors: Weikang Ai, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University

Abstract Preview: Purpose: Real-time tumor tracking is critically important for respiratory motion management for lung cancer radiotherapy. A previously proposed application of a photon counting detector involves measu...

Establishing Radiotherapy in Malawi through an International Medical Physics Collaboration

Authors: Ruth Afanador, Daniela Branco, John M Bryant, John Campbell, Clement Chaphuka, Samuel A. Einstein, David B. Flint, Jeffrey R. Kemp, Mussa Kumwembe, Daniel J Mollura, Joseph Weygand

Affiliation: RAD-AID International, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, UNC Health, Malawi National Cancer Center, Kamuzu Central Hospital, Penn State College of Medicine, Sutter Health, New York University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: Malawi, a landlocked country in southeastern Africa with a population of over 20 million, ranks among the world’s least-developed nations and has the fourth-lowest gross domestic product per ...

Evaluating Commercial Auto-Segmentation Software: Is Performance on Pediatric Organs-at-Risk Accurate?

Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...

Evaluating Normal Tissue Toxicity Following Pulsed Low Dose Rate Radiotherapy

Authors: Shahabeddin mostafanazhad Aslmarand, Lili Chen, Dusica Cvetkovic, Troy A. Dos Santos, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose:
Pulsed low-dose-rate radiotherapy (PLDR) has been proposed to reduce normal tissue toxicity while maintaining tumor control comparable to conventional radiotherapy (CRT). This study assess...

Key Tumor Volume Zones for Advancing the Radiomics-Based Distant Recurrence Prediction

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...

Lymph Node Malignancy Prediction in Head and Neck Cancer Using a Graph Neural Network

Authors: Liyuan Chen, Meixu Chen, Bowen Jing, Sepeadeh Radpour, Erich Josef Schmitz, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Prospective clinical trials have shown that involved nodal radiation therapy (INRT) can substantially improve patients’ quality of life without increasing the risk of elective nodal failure. ...

Voxel-Based Radiobiological Modelling for Evaluating Radiotherapy Treatment Plans in Relation to Radiation-Induced Acute Mucosal Toxicity (including oral and pharyngeal mucositis): A Single-Institutional Study Focused on Head-and-Neck Carcinoma.

Authors: Rama Bhawani, Mary Joan, Ajay Katake, Munish Kumar, Chhape Ram, Megha Sharma, Balbir Singh, Vikram Singh

Affiliation: SLBSGMC & HOSPITAL, MOHANDAI OSWAL HOSPITAL, WOCKHARDT HOSPITAL, Christian Medical College and Hospital,, AMERICAN ONCOLOGY INSTITUTE

Abstract Preview: Purpose: This study aims to evaluate the utility of voxel-based radiobiological modelling in assessing IMRT radiotherapy treatment plans concerning radiation-induced acute mucosal toxicity, specifical...