Authors: Beth M. Beadle, Adrian Celaya, Laurence Edward Court, David Fuentes, Anna Lee, Tze Yee Lim, Dragan Mirkovic, Amy Moreno, Raymond Mumme, Tucker J. Netherton, Callistus M. Nguyen, Jaganathan A Parameshwaran, Jack Phan, Carlos Sjogreen, Sara L. Thrower, Congjun Wang, He C. Wang, Xin Wang
Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, Stanford University, The University of Texas MD Anderson Cancer Center, MD Anderson Cancer Center, MD Anderson, Rice University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Quality assurance of target volumes from radiotherapy clinical trials is a labor and resource intensive task. The purpose of this work is to quantify the accuracy of a tool that automatically...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Joyoni Dey, Hunter Cole Meyer, Murtuza Taqi
Affiliation: Louisiana State University
Abstract Preview: Purpose: We propose using super-resolution methods for X-ray grating interferometry without an analyzer with detectors that fail to meet the Nyquist sampling rate needed for traditional image recovery...
Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...
Authors: Sarah A. Ashmeg, Travis James McCaw, Joseph Shields, Matthew Spector, Christopher Tyerech, Christopher T Wilke
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: Patients with oral cavity cancer often undergo surgical extirpation prior to radiation, and surgical implants are utilized to reconstruct the resulting defect. This study dosimetrically evalu...
Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging is a powerful tool for localizing entrance and exit dose during radiotherapy treatment. The current implementation uses an intensified-CMOS (iCMOS) camera allowing for high-...
Authors: Yuemeng Feng, Hamid Sabet
Affiliation: Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: We propose a novel brain-dedicated PET system comprising elliptical cylinder with a neck cut-out, supplemented by front and back panels to improve sensitivity and line-of-response sampling. T...
Authors: Austen N. Curcuru, Arash Darafsheh, Winter Green, Yao Hao, Baozhou Sun, Tiezhi Zhang, Tianyu Zhao, Xiandong Zhao
Affiliation: WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Washington University in St. Louis, University of South Florida, Baylor College of Medicine
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) requires precise setup imaging due to the sharp dose gradients and rapid distal fall-off seen in proton therapy dose distributions. Additionally, onl...
Authors: Ted Bartley, Steven Brown, Steven Chinn, Mike Hopkins, Stanley Leong, Jerimy C. Polf, Luke Rothermel, Scott Sawyer, Benjamin L. Viglianti
Affiliation: University of California School of Medicine, University of Michigan, H3D, inc, University Hospitals, M3D, Inc, M3D Imaging, California Pacific Medical Center
Abstract Preview: Purpose: In a collaboration between surgical oncologists and medical physicists, a new intra-operative gamma camera for imagining sentinel lymph nodes (SLN) during radio-guided SLN biopsy procedures h...
Authors: Petr Bruza, Eric R. Fossum, Alexander Geiersbach, David J. Gladstone, Karthik Raj Venkatesan
Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Current Cherenkov imaging sensors rely on image intensifiers to generate sufficient signal for photon detection. While image intensifiers (IIs) exhibit good Cherenkov photon signal response, ...
Authors: Madeleine Arbogast, David Dorndos, Denise E Foltz, Justin Fraser, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Neurosurgery, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: For stereotactic radiosurgery (SRS) treatments of intracranial arteriovenous malformations (AVM) and fistulas (AVF), same-day Leksell Gamma Knife (GK) is the preferred modality. Long-term cli...
Authors: Milad BaradaranGhahfarokhi, Manuel A. Morales Paliza
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: The purpose of this study was to commission Varian HDR surface applicators using a high-resolution diode array and film dosimetry. This work evaluates dosimetric characteristics of these appl...
Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang
Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...
Authors: Srinivas Cheenu Kappadath, Brian Michael Kelley, Benjamin P. Lopez
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Imaging systems are subject to errors from finite spatial resolution and voxel size. This work demonstrates their effect on dose algorithm {Monte Carlo (MC), dose-volume kernel (DVK), and ...
Authors: Nathalie Correa, Janet Ching-Mei Feng, Chun-Han Huang, Jimmy Huynh
Affiliation: UTHealth McGovern Medical School
Abstract Preview: Purpose: To compare the image quality and the dose-area product (DAP) of four mobile digital radiography (DR) systems—Canon (Soltus 500), Shimadzu (MobileDaRt Evolution MX8), Solution for Tomorrow (M1...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Iterative reconstruction (IR) methods are valuable for reducing dose in modern CT; however, IR methods have the effect of reducing spatial resolution and hence the lesion edge sharpness. Furt...
Authors: Go Akamatsu, Yuma Iwao, Kurumi Narita, Hideaki Tashima, Taiga Yamaya, Eiji Yoshida
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In brain positron emission tomography (PET), higher spatial resolution is better for visualizing detailed structures such as small nuclei and the layered structure of the cerebral cortex. The...
Authors: Dukagjin Blakaj, Zhilin Hu, Stephen Kang, Abberly Lott Limbach, Lanchun Lu, Henry Xiang, Jie Zhang
Affiliation: Pharostek, Department of Pediatrics, The Ohio State University, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiology, University of Kentucky, Department of Pathology, The Ohio State University, Department of Radiation Oncology, The Ohio State University, Department of Otolaryngology, The Ohio State University
Abstract Preview: Purpose: Detect surgical margin in vivo using an original barcode-reading type portable OCT imaging system.
Methods: We developed a barcode-reading type portable optical coherence tomography (OCT) ...
Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira
Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio
Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Jing Feng, Wenzheng Feng, Joseph Hanley, Jeff Stainsby, Tingyu Wang
Affiliation: Synaptive Medical, Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose:
The Synaptive MRI is a 0.5T superconducting head only system (first US install 2023). This is the first study that evaluates the geometric accuracy using a Sun Nuclear MR Distortion and Im...
Authors: Junghoon Lee, Todd R. McNutt, Harry Quon, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Xerostomia is a common toxicity in head and neck cancer (HNC) radiotherapy (RT). A few deep learning (DL) models have been proposed to predict the chance of xerostomia 12 months after RT with...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Cheng-Chieh Cheng, Jeffrey P Guenette, Yajun Li, Bruno Madore, Lei Qin
Affiliation: Brigham and Women's Hospital, National Sun Yat-sen University, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Pilot tone (PT), a compact RF sensor, has been integrated into clinical practice for motion detection. Prior studies proposed mapping PT signals to head positions using a calibration step tha...
Authors: So Hyun Ahn, Chris Beltran, Byongsu Choi, Jeong Heon Kim, Jin Sung Kim, Bo Lu, Justin Chunjoo Park, Bongyong Song, Jun Tan
Affiliation: Mayo Clinic, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, UC San Diego, Yonsei University College of Medicine
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) is widely used in IGRT for patient positioning but suffers from low resolution and poor soft tissue contrast. Synthetic CT (sCT) generated from CBCT ad...
Authors: Yu Gao, Lei Xing, Siqi Ye
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Samuel L. Brady, Joseph G. Meier
Affiliation: Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...
Authors: Mohammadreza Ay, Nahal Daneshgar, Nima Kasraie, Abbas Monsef, Zeinab Peymani, Hadi Rezaei, Peyman Sheikhzadeh
Affiliation: University of Minnesota Medical School, Radiation Oncology, Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Shiraz University of Medical Sciences, Department of Medical Physics, Tehran University of Medical Sciences, Department of Medical Physics and Biomedical Engineering, UT Southwestern Medical Center, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose:
This study aims to design and simulate an innovative pediatric-dedicated SPECT scanner optimized for children’s unique anatomical and safety needs by enhancing sensitivity in data acquisit...
Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu
Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...
Authors: Andres Portocarrero Bonifaz, Ian Schreiber
Affiliation: CARTI Cancer Center
Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...
Authors: Matthew R. Hoerner, Allison Shields
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose: To investigate the quality and clinical utility of chest x-rays synthesized from CT scans (sCXR).
Methods: Five helical chest CT exams were chosen for evaluation: this cohort represented a...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, D. Michael Lovelock, Charlotte Elizabeth Read, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for precise motion management in MRI-guided radiotherapy (MRIgRT). While 2D Cine MRI offers high temporal resolution for motion tracking, it inherently l...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Stephanie Bennett, Ross I. Berbeco, Ning Jin, Sonal Josan, Justin Michael Sheetz, Atchar Sudhyadhom
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Massachusetts - Lowell, Siemens Healthineers, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women's Hospital
Abstract Preview: Purpose: AGuIX, a Gadolinium-based theranostic radiosensitizing nanoparticle, is currently under clinical evaluation in Europe and the US. Using patients from the double-blinded NanoBrainMets trial, u...
Authors: Salahuddin Ahmad, Imad M. Ali, Zaid Alkalani, Nesreen Alsbou
Affiliation: University of Oklahoma, University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: To design and evaluate a 3D-detector for proton CT-imaging and radiography, utilizing volumetric plastic scintillator detector exposed to high-energy therapeutic beams from proton therapy sys...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Casey C. Heirman, Kyle J. Lafata, Xiang Li, Breylon Riley, Jack B Stevens, Tammara Watts
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: To leverage quantitative fluorescence imaging and spatial transcriptomics for characterizing the spatial and molecular heterogeneity of the tumor microenvironment (TME) in HPV+ head and neck ...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Hadley Anna DeBrosse, Kevin J. Little
Affiliation: The Ohio State University
Abstract Preview: Purpose: This work examines the consistency and pattern of spatial resolution degradation in weekly quality control (QC) testing prior to CT tube failure and replacement and investigates potential cor...
Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman
Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University
Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...
Authors: Jing Qian, Brandon Reber, David M. Routman, Satomi Shiraishi
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The dose distribution in proton radiotherapy (PRT) is characterized by sharp gradients, posing a challenge for machine learning-based dose prediction. While denoising with diffusion processes...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...