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Results for "sample random": 10 found

A Multi-Regional and Multi-Omics Approach to Predict Penumonitis in Patients with Locally Advanced Non-Small Cell Lung Cancer in Nrg Oncology Trial RTOG 0617

Authors: Katelyn M. Atkins, Indrin J. Chetty, Elizabeth M. McKenzie, Taman Upadhaya, Samuel C. Zhang

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose:
We explored a multi-regional and multi-omics approach to extract CT-based radiomics and 3D dosiomics features to predict radiation pneumonitis (RP) in patients with locally advanced Non-Sm...

An Open-Access Toolkit to Generate Realistic CT and Low-Field MR Images Based on an Xcat Phantom

Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu

Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell

Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...

Beyond Correlation: An Ultra-Large Physics-Driven Vascularized Tumor Model to Bridge Feature Formation with Underlying Biology

Authors: Jiayi Du, Lihua Jin, Ke Sheng, Yu Zhou

Affiliation: Harvard University, University of California, San Francisco, UCLA, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Radiomics enables powerful insights into tumor biology through non-invasive imaging, excelling in diagnostic and prognostic predictions. However, due to a lack of mechanistic connections, que...

Correlated Pharmacokinetic Models in Targeted Alpha Therapy

Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller

Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona

Abstract Preview: Purpose: To sample correlated k-constants in tissue-compartment model for pharmacokinetic study in targeted alpha therapy.
Methods: This work simulated the biodistribution of PSMA-11 tracers labele...

Leveraging Codex-Based Spatial Profiling of the Tumor Microenvironment in Concurrent Radiation Therapy and Immunotherapy

Authors: Todd A Aguilera, Bassel Dawod, Sebastian Diegeler, Eslam Elghonaimy, Purva Gopal, Jiaqi Liu, Hao Peng, Arely Perez Rodriguez, Nina N. Sanford, Robert Timmerman, Megan B Wachsmann, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: This study pioneers the integration of CODEX (co-detection by indexing)-based spatial profiling and advanced computational techniques to investigate the tumor immune microenvironment (TIME) i...

Non-Contact Electroacoustic Imaging Monitoring Electroporation Therapy

Authors: Zhongping Chen, Yuchen Song, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of California, Irvine, University of California Irvine

Abstract Preview: Purpose: Electroacoustic tomography (EAT) monitors the distribution of electrical energy in tissues by detecting acoustics signals induced by electrical pulses during irreversible electroporation (IRE...

Poisson Decay in Pharmacokinetics with Imaging in Targeted Alpha Therapy

Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller

Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona

Abstract Preview: Purpose: To sample random numbers of decay of radiotracers in a pharmacokinetic compartment model for Monte-Carlo simulation of imaging in targeted alpha therapy.
Methods: Time-activity curves (TAC...

Quality Monitoring of Temporal Performance Degradation in Clinical Use of AI Auto-Segmentation

Authors: Ali Ammar, Quan Chen, Jingwei Duan, Yi Rong, Nathan Y. Yu, Libing Zhu

Affiliation: Mayo Clinic Arizona, University of Alabama at Birmingham

Abstract Preview: Purpose: Clinical performance of deep learning-based auto-segmentation (DLAS) can degrade over time due to AI β€œaging” from unseen data input compared to the initial model training data. This study aim...

Rapid Reconstruction of Extremely Accelerated Liver 4D MRI Via Chained Iterative Refinement

Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger

Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.

Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...

Skin Lesion Subtype Classification Using Lesion and Border Radiomic Features

Authors: Rituparna Basak, Maede Boroji, Renee F Cattell, Vahid Danesh, Imin Kao, Kartik Mani, Xin Qian, Samuel Ryu, Tiezhi Zhang

Affiliation: Stony Brook Medicine, Stony Brook University, Washington University in St. Louis, Stony Brook University Hospital

Abstract Preview: Purpose: Fundamental qualitative characteristics physicians use to differentiate skin lesion subtypes include asymmetry, border irregularity, and color. Radiomic features have potential to quantify th...