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Results for "scattering proton": 16 found

A Novel Semi-Analytic Approach for Dose Calculation in Proton Minibeam Radiotherapy

Authors: Hao Gao, Wangyao Li, Yuting Lin, Chao Wang, Wei Wu

Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Proton minibeam radiation therapy (pMBRT) delivers a unique peak-and-valley dose pattern using collimators with narrow slits, offering improved normal tissue sparing compared to conventional ...

Backscattering of Compton Cameras: A Monte Carlo Simulation Approach

Authors: Jorge Naoki Dominguez Kondo, Qihui Lyu

Affiliation: University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
Targeted alpha therapy (TAT) has emerged as a highly potent therapeutic method in oncology, but its development is limited by the lack of imaging methods to quantify its dosimetry. Convent...

Backward Photon Monte Carlo Propagator (BPMCP): Proof of Concept of a Fully Physics-Driven SPECT Reconstruction

Authors: Alejandro Bertolet, Carlos Huesa-Berral, Victor V. Onecha

Affiliation: Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Radioembolization for liver tumors using 90Y microspheres uses SPECT as confirmatory dosimetry, although 90Y is a pure Ξ²-emitter, and SPECT-imaging is only available through subsequent bremss...

Correcting for the Cherenkov-to-Dose Conversion for Tset Patients Using Monte Carlo Simulations

Authors: Baozhu Lu, Timothy C. Zhu, Yifeng Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: Cherenkov intensity can be quantitatively correlated to surface dose but need certain corrections for accurate dose measurements. This study aims to investigate the impact of incident beam an...

Creation of Proton Minibeams in a Pbs Nozzle from Low Emittance Source Beams

Authors: Seung Yeon Kim, Grant A. McAuley, Ju A Park, Jerry D Slater

Affiliation: Loma Linda University

Abstract Preview: Purpose: The production of proton minibeams in standard PBS nozzles is challenging due to the effects of finite source beam divergence and multiple Coulomb scattering. Herein we investigate the use of...

Development of a GPU-Based Dose Calculation Engine for MRI-Guided Proton Therapy

Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...

Energy Dependency of Biological Effects from Radiation Scattering Around Medical Implants in Particle Therapy

Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum

Affiliation: Osaka University, Texas A&M University

Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...

Enhanced Surface Dose Accuracy in Proton Treatment Planning: Optimizing External Volume HU Thresholding.

Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez

Affiliation: University of Miami

Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...

Impact of Physics Modeling on Monte Carlo Normal Tissue Dose Reconstructions for Passive Scattering Proton Therapy Patients

Authors: Caroline Esposito, Keith T Griffin, Jae Won Jung, Choonik Lee, Choonsik Lee, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock

Affiliation: East Carolina University, University of Michigan, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: The National Cancer Institute’s Pediatric Proton and Photon Therapy Comparison Cohort aims to collect and analyze data from cancer centers across the United States and Canada to quantify diff...

Impact of Translucent Sheet Bolus and Melanin Concentration on Recorded Optical Signal during Cherenkov Imaging in External Beam Radiation Therapy

Authors: Jacqueline M. Andreozzi, Savannah Decker, Diego Hernandez, Iman R. Washington

Affiliation: UC San Diego, Department of Radiation Oncology, Moffitt Cancer Center, University of South Florida, Moffitt Cancer Center

Abstract Preview: Purpose: Recent advances in external beam radiation therapy have begun to explore the utility of Cherenkov radiation imaging as a beam delivery visualization tool. When sheet bolus is used during trea...

Improvements from Monte Carlo Simulations over Pencil Beam Algorithms for Normal Tissue Dose Reconstruction in Proton Therapy Patients

Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock

Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research

Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...

Monte Carlo Simulation and Dosimetric Verification of 3D Range Modulators for a Multi-Field-Optimization Flash-IMPT Plan

Authors: Michael M Folkerts, Miriam Krieger, Pierre Lansonneur, Gerard Paquet, Petar Penchev, Christoph Schuy, Yuri Simeonov, Uli Weber, Klemens Zink

Affiliation: GSI Helmholtzzentrum fuer Schwerionenforschung, Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences, Varian Medical Systems

Abstract Preview: Purpose:
Ultra-high dose-rate proton irradiation may spare the healthy tissue (FLASH-effect). The 3D-range-modulator (3D-RM) method reduces the treatment time compared to conventional IMPT and can ...

On the Spectral Changes of Magna-Field Photon Beams Used in Total Body Irradiation

Authors: Larry A. DeWerd, Ahtesham Ullah Khan

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: Total body irradiation (TBI) technique uses high energy photon beams with extended source-to-surface distances (SSDs) to irradiate the entire patient to prepare them for bone marrow or stem c...

Proton Therapy Treatment Planning for Thoracic Cancer: A Comparative Analysis of Single and Multi-Field Plans

Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu

Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection

Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...

Radiation Shielding Considerations for Ultra-High Dose Rate Electron Flash Radiation Therapy

Authors: Alexandru Badalan, Peter Petric, I. Antoniu Popescu, Andrew Kyle Henderson Robertson

Affiliation: Bc Cancer, BC Cancer - Vancouver, BC Cancer

Abstract Preview: Purpose: Ultra-high dose rate (>40 Gy/s) or β€œFLASH” radiation therapy (RT) has the potential to improve cancer treatment through reduced radiation side effects. While electron FLASH beams can be produ...

Remote Evaluation of Flash Beamlines for Electron, Proton, and MV Photons

Authors: Alexander Baikalov, Luke Connell, Nolan M. Esplen, Michele M. Kim, Stephen F. Kry, Emil Schueler, Hayden Scott, Ryan Sun, Paige A. Taylor, Uwe Titt

Affiliation: The University of Texas MD Anderson Cancer Center, University of Pennsylvania, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: to develop an affordable, portable device for accurately measuring FLASH dose rates from protons, electrons, and photons. 4 detectors were utilized to measure the temporal structure of proton...