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Results for "source receiver": 12 found

An International Survey of High Dose Rate Brachytherapy Dosimetry Practices

Authors: Anna Becker, Tomislav Bokulic, Mauro Carrara, Krzysztof Chelminski, Larry A. DeWerd, Alexis Dimitriadis, Benjamin Kellogg, Malcolm R. McEwen, Zakithi L.M Msimang, Mark J. Rivard, Thorsten Sander, Thorsten Schneider, Jamema Swamidas, Egor Titovich, Paula Toroi, Carlos E. de Almeida, Jacco de Pooter, Liset de la Fuente Rosales, Deborah G. van der Merwe

Affiliation: Radiation and Nuclear Safety Authority, University of Zagreb, National Physical Laboratory, IAEA, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Rio de Janeiro State University, Dosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Physikalisch-Technische Bundesanstalt, National Metrology Institute, University of the Witwatersrand, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, National Research Council, Warren Alpert Medical School of Brown University

Abstract Preview: Purpose: The recently published IAEA-TRS-492 international code of practice (CoP) aims at improving traceability, accuracy, and consistency in Brachytherapy Dosimetry. To assess current approaches to ...

Computational Prototype Single-Channel Vaginal Cylinder with Integrated Filter to Address Dose Uniformity in High-Dose-Rate Brachytherapy for Endometrial Cancer

Authors: Brett Bocian, Patrick James Jensen, Luis Augusto Perles, Christopher J. Tien

Affiliation: Yale University School of Medicine, University of Miami, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: Guidelines for dose prescriptions in endometrial cancer are based upon depth from the cylinder, traditionally 5 mm or 0 mm (i.e., surface). There are no current single-channel vaginal cylinde...

Evaluating LiF:Mg,Ti TLD Reliability at Body Temperature for Long-Term Dose Monitoring

Authors: Larry A. DeWerd, Keith A. Kunugi, Autumn Rasmussen

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: Ensuring the validity of the thermoluminescent dosimeter (TLD) response requires verifying that signal fading—defined by a reduction in stored signal—is well-known and corrected for under the...

Feasibility of Extracting Diagnosis and Staging at Scale from Clinical Notes Via a Real-World Data Warehouse

Authors: Melissa Bronson, Elizabeth L. Covington, Robert T. Dess, Joseph R. Evans, William C. Jackson, Charles S. Mayo, Michelle L. Mierzwa, Benjamin S. Rosen, VG Vinod Vydiswaran, Grant Weyburne, Zheng Zhang, Henry Zocher

Affiliation: PCORnet®, The National Patient-Centered Clinical Research Network, University of Michigan

Abstract Preview: Purpose: Diagnosis and staging are an integral part of cancer care, but this information is often scattered across various electronic medical records. The fragmentation increases overall documentation...

Impact of Six Degrees of Freedom Intrafraction Motion on Target Coverage for Single-Isocenter Multi-Target Stereotactic Radiosurgery

Authors: Anupama Chundury, Hyejoo Kang, John C. Roeske, Iris A. Rusu

Affiliation: Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose: To quantify the dosimetric impact of six degrees of freedom (6DoF) intrafractional errors on gross tumor volume (GTV) and planning target volumes (PTV) for single-isocenter multi-target stere...

Implementing TG-191 for Robust Calibration of Scintillation Imaging As a Clinical dosimetry Tool

Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous

Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health

Abstract Preview: Purpose: Scintillation imaging has demonstrated unique advantages to existing clinical in vivo dosimetry (IVD) techniques by enabling full-field visualization, direct comparison to the treatment plan,...

Investigating the Flash Effect: Uncovering Brain Sparing and Cognitive Preservation across Varying Dose Rates in Whole-Brain Irradiation of in-Vivo Mouse Models

Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu

Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center

Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...

Just-in-Time Quality Assurance Check for Yttrium-90 Radioembolization Therapy

Authors: Stewart J. Becker, Andrew Genuit, Mariana Guerrero, Yannick P. Poirier

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: To introduce an additional quality assurance step to prevent human error in vial mix-ups during Yttrium-90 (Y90) radioembolization by verifying the local assay at the time of delivery. We pro...

Quantification of Chemical Species Yield and Radiation Damage Patterns for Radiopharmaceutical Therapy Isotopes: Lu-177, Y-90 and I-131

Authors: Zakaria Aboulbanine, Greeshma A. Agasthya, Paul Inman, Anuj J. Kapadia, Anthony Hong Cheol Lim, Jayasai Ram Rajagopal

Affiliation: Oak Ridge National Laboratory, Georgia Institute of Technology

Abstract Preview: Purpose: The fundamental concept of radiopharmaceutical therapy involves binding radioisotopes to molecules with a known biokinetic distribution, which ensures that the targeted organs receive higher ...

Quantifying the Impact of Tissue Inhomogeneities on Calculated Dosimetry within LDR Brachytherapy

Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson

Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer

Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...

Radionuclide Therapy Patient Release Dose Calculation Using a Non Point Model

Authors: Tianliang Gu

Affiliation: UT Health Science Center at Houston

Abstract Preview: Purpose:
In Nuclear Regulatory Commission guide 8.39 on releasing patients administered radioactive material, the dose is calculated assuming both the source and receiver are points. This point mod...

Real-Time Observation of Radiation-Induced DNA Damage for Radiopharmaceuticals

Authors: Denis Bergeron, Brittany Broder, Sean Jollota, Ahtesham Ullah Khan, Michael Lamontagne, Joseph W. Robertson

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, National Institute of Standards and Technology

Abstract Preview: Purpose: We present new methodology for real-time measurement of radiation-induced DNA damage caused by radiopharmaceuticals. Building on previous efforts to measure DNA fragmentation with nanopore se...