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Results for "sparse space": 12 found

A Framework for Automated Selection of Dose-Volume Objectives to Improve Radiation-Induced Immune Suppression (RIIS)-Related Overall Survival (OS) Following Chemo-Radiotherapy

Authors: Gabriel Lucas Andrade de Sousa, Einsley-Marie Janowski, Cam Nguyen, Krishni Wijesooriya

Affiliation: Department of Radiation Oncology, University of Virginia, Department of Physics, University of Virginia

Abstract Preview: Purpose: Optimizing radiation therapy (RT) to spare the immune system may improve Overall Survival (OS) in cancer patients. This study develops a computational algorithm to identify optimal dose-volum...

An Adaptive Radiotherapy Approach Sparing Preirradiated Critical Structures

Authors: Mohamed Bahaaeldin Mohamed Afifi, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Chang Ming Charlie Ma, Robert A. Price

Affiliation: Fox Chase Cancer Center, Radiological Sciences and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University.

Abstract Preview: Purpose: Reirradiation of recurrent cancer or a newly developed lesion in a proximal location poses a challenge for radiation treatments. This is occasionally encountered in many modern clinics and ef...

Data-Driven Forward Projector for Optimization of the Proton Stopping Power Calibration in Treatment Planning Based on Sparse Proton Radiographies

Authors: Hector Andrade-Loarca, Ines Butz, Chiara Gianoli, Prof. Gitta Kutyniok, Jianfei Li, Katia Parodi, Prof. Vincenzo Patera, Angelo Schiavi, Prof. Ozan Öktem

Affiliation: Sapienza University of Rome, Department of Mathematics, Royal Institute of Technology, School of Computation, Information and Technology, Technische Universitaet Muenchen, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Mathematics, Ludwig-Maximilians-Universität (LMU) München, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München

Abstract Preview: Purpose: To explore and demonstrate the feasibility of accurate and fast prediction of the water equivalent thickness (WET) distribution of tissue traversed by a proton imaging pencil beam, aiming at ...

Development and Clinical Validation of Hyperarc Stereotactic Radiosurgery Method for Intraocular Tumors

Authors: Chase Cochran, Damodar Pokhrel, William St Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...

Enhance Four-Dimension Cone-Beam Computed Tomography (4D-CBCT) from Sparse Views Using a Novel Deep Learning Model

Authors: Lei Ren, Jie Zhang

Affiliation: University of Maryland School of Medicine

Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...

Functional MRI Guided Partial Tumor Irradiation to Improve Tumor Control and Spare Tumor Microenvironment

Authors: Bingqi Guo, Ping Xia

Affiliation: Cleveland Clinic

Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a “GRID” or “lattice” of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...

High-Temporal Dynamic CBCT Imaging Via Gaussian Neural Representation

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study introduces a novel spatiotemporal Gaussian neural representation framework to reconstruct high-temporal dynamic CBCT images from 1-minute acquisition, preserving motion dynamics an...

Investigating the Radiation Chemistry of Flash Radiation Therapy through Electron Paramagnetic (EPR) Spectroscopy

Authors: Ramin Abolfath, Alexander Baikalov, Stefan Bartzsch, Nolan M. Esplen, Alan Eduardo Lopez Hernandez, Emil Schueler

Affiliation: MD Anderson Cancer Center, PI Experimental Medical Physics, Institute of Radiation Medicine (IRM), Helmholtz Munich, Germany, Howard University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: FLASH radiation therapy (FLASH-RT) leverages ultra-high dose rates (UHDR) to spare normal tissue as compared to conventional (CONV)-RT while preserving tumor control; this is termed the FLASH...

Monte Carlo Simulation and Dosimetric Verification of 3D Range Modulators for a Multi-Field-Optimization Flash-IMPT Plan

Authors: Michael M Folkerts, Miriam Krieger, Pierre Lansonneur, Gerard Paquet, Petar Penchev, Christoph Schuy, Yuri Simeonov, Uli Weber, Klemens Zink

Affiliation: GSI Helmholtzzentrum fuer Schwerionenforschung, Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences, Varian Medical Systems

Abstract Preview: Purpose:
Ultra-high dose-rate proton irradiation may spare the healthy tissue (FLASH-effect). The 3D-range-modulator (3D-RM) method reduces the treatment time compared to conventional IMPT and can ...

Patient-Specific Ultra-Sparse k-Space Reconstruction Using Motion Decomposition and Sinusoidal Representation Networks for Dynamic Volumetric MRI in Radiotherapy

Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center

Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...

Rapid Reconstruction of Extremely Accelerated Liver 4D MRI Via Chained Iterative Refinement

Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger

Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.

Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...

Weakly Supervised Spatial Implicit Neural Representation Learning for 3D MRI-Ultrasound Deformable Image Registration in HDR Prostate Brachytherapy

Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center

Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...