Authors: Suman Gautam, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-specific quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...
Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal
Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...
Authors: Jonathan Dowell, Grace Francis, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Iridesce Solutions, Inc.
Abstract Preview: Purpose: A novel radiation therapy quality assurance (RT QA) device has been designed, constructed and tested. The nüFilmTM machine QA system provides a method for collecting light, mechanical and rad...
Authors: Chase Cochran, Shane McCarthy, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Manually generating intraocular stereotactic radiosurgery (SRS) plans involves significant challenges, including lengthy planning times and inter-planner variability. Knowledge-based SRS plan...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Kellin M De Jesus, Leon Dunn, Les Sztandera, David H. Thomas
Affiliation: IsoAnalytics Pty. Ltd., Thomas Jefferson University
Abstract Preview: Purpose: Machine accuracy and performance are critical for ensuring the safety and efficacy of intensity-modulated radiotherapy (IMRT and VMAT). This study aims to analyze a large and diverse set of l...
Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Mark E Artz, Jiyeon Park, Lori Rice, Mohammad Saki, Sanjeev Shukla, Michael Vieceli
Affiliation: University of Florida Health Proton Therapy Institute, Department of Radiation Oncology, University of Florida College of Medicine, UF Health Proton Therapy Institute, Department of Urology, University of Florida College of Medicine
Abstract Preview: Purpose: To investigate how varying levels of DNA repair mutations affect the LET sensitivity of prostate cancer cells.
Methods: The prostate cancer cell lines Du145 (low DNA repair mutations), PC3...
Authors: Ahmet S. Ayan, Austin M. Faught, Eunsin Lee, Julia Pakela
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University
Abstract Preview: Purpose: To present commissioning of a fixed beamline ultra-high dose rate proton pencil beam scanning system, the world’s first multi-room Varian ProBeam360⁰
Methods: The fixed beamline pencil bea...
Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago
Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...
Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...
Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...
Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...
Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav
Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)
Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...
Authors: Diandra Ayala-Peacock, Lindsey Hendricks Bloom, Oana I. Craciunescu, Julie A. Raffi, Megan K. Russ, Ryan Sanford, Rajesh Venkarataman
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, Duke University Medical Center, Duke University, Eigen Health, Duke Univesity
Abstract Preview: Purpose: To establish a robust QA framework to characterize and ensure accuracy, reliability, and reusability of a transrectal ultrasound (TRUS)-based needle tracking system (NTS) for clinical HDR GYN...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC
Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Min-Sig Hwang, Danny K. Lee, Daniel C. Pavord, Kyung Lim Yun
Affiliation: Allegheny Health Network
Abstract Preview: Purpose: Ensuring the quality of treatment plans through patient-specific pre-treatment quality assurance (QA) is essential. However, the use of physical phantom-based QA devices is not feasible for o...
Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh
Affiliation: Tufts Medical Center
Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Catherine Coolens, Robert K. Heaton, Lalageh Mirzakhanian, Tasnim Rahman, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, McGill University, Princess Margaret Cancer Centre, Princess Margaret Hospital, University of Toronto
Abstract Preview: Purpose: Commissioning of a Gamma Knife® (GK) (Elekta, Sweden) unit requires precise dosimetric reference measurements, particularly for small fields. The IAEA TRS-483/AAPM TG-155 code of practice (20...
Authors: Hulya Ozdemir Buss, Jeffrey Geiger, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: The Radixact Synchrony system integrates real-time motion tracking and compensates to improve treatment accuracy for moving targets. This study presents a streamlined and efficient quality as...
Authors: Rachel B. Ger, Heng Li, Anh Tran
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients undergo quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and utilize robustness scenarios for setup and range uncertainties. For intra...
Authors: Zhihua Qi
Affiliation: Henry Ford Health
Abstract Preview: Purpose: State of the art cardiac CT has built-in automated, patient specific optimization, taking into account a number of factors including patient size, heart rate and others. It is crucial to deve...
Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna
Affiliation: UNAM, Medica Sur
Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...
Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din
Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University
Abstract Preview: Purpose: This study introduces a novel approach for patient-specific quality assurance in proton beam therapy, utilizing new plastic scintillator detectors with high temporal resolutions to create det...
Authors: James L. Giltz, Michael J. Merrick
Affiliation: Alyzen Medical Physics, University of Kentucky
Abstract Preview: Purpose: To evaluate the capability of MyQA SRS in performing high-resolution machine QA to verify multileaf collimator (MLC) behavior and integrity for adaptive radiotherapy (ART). This study demonst...
Authors: Kristofer K. Kainz, Eenas A. Omari, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: We present our therapy physics residency program’s revisions to its training structure, with the goals of more efficient clinical education and preservation of the residency’s clinical suppor...
Authors: Weixing Cai, Laura I. Cervino, Qiyong Fan, Yabo Fu, Tianfang Li, Xiang Li, Jean M. Moran, Hai Pham, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: AAPM Task Group Report 273 emphasizes the importance of rigorous validation to ensure the generalizability and robustness of machine learning-based clinical tools before their implementation ...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...
Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison
Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...