Authors: David Chighvinadze, Lisa Czaplicki, Jeremy D. Donaghue, Lama K. Muhieddine Mossolly
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic Strongsville, Cleveland Clinic Fairview
Abstract Preview: Purpose:
Current electron block generation requires manual cutting of stryofoam and placement for pouring of the block which can lead to possible miscutting of blocks, and non-accurate rotations co...
Authors: Odunola Grace Babawale, B. Gino Fallone, Alireza Gazor, Andrei D. Ghila, Patricia A. K. Oliver, Michael W. Reynolds, Keith D. Wachowicz, Tania Rosalia Wood, Shima Y. Tari, Eugene Yip, Jihyun Yun
Affiliation: Nova Scotia Health, Dept. of Medical Physics and Dalhousie University, Dept. of Physics and Atmospheric Science, Dept. of Radiation Oncology, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com, Department of Medical Physics, Arthur J. E. Child Comprehensive Cancer Centre, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Department of Medical Physics, BC Cancer, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute
Abstract Preview: Purpose: To evaluate the dose to a moving target and its surroundings in a magnetic field using 4D-Monte-Carlo (MC) simulation.
Methods: The study utilizes a previously validated MC model of our li...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Aman Anand, Jonathan B. Ashman, Martin Bues, Brady S. Laughlin, Lisa McGee, Justin Pettit, Fan Yang, Libing Zhu
Affiliation: Department of Radiation Oncology Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: Proton therapy (PT) offers significant clinical and economic benefits across various cancers, whereas it also has faced skepticism due to its historically high costs and perceived overuse in ...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine
Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...
Authors: Sijuan Huang, Zi LIU, Jing MA, Xin Yang
Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China
Abstract Preview: Purpose: To reduce the pressure of manual review of abnormal situations in manually/automatically delineated regions of interest (ROI), improve its accuracy and basis.
Methods: 220 radiotherapy pat...
Authors: Danna Gurari, Moyed Miften, Sarah Milgrom, Atharva Rajesh Peshkar, Willem Schreuder, David H. Thomas
Affiliation: University of Colorado Boulder, University of Colorado School of Medicine, University of Colorado Anschutz, Thomas Jefferson University
Abstract Preview: Purpose: To evaluate the accuracy of a novel avatar-based patient positioning technique.
Methods: We developed a modified surface-guided radiation therapy (SGRT) technique, 'Avatar-Guided Radia...
Authors: Brianna Baek, David J. Carlson, Zhe (Jay) Chen, Dae Yup Han, Bon Tack Koo, Hyojun Park
Affiliation: Columbia University, Canyon Crest Academy, Department of Therapeutic Radiology, Yale University School of Medicine, Department of Radiation Oncology, Chung-Ang University Gwang Myeong Hospital
Abstract Preview: Purpose: To find an optimized treatment technique and shielding design for minimizing the dose to a fetus, a Monte-Carlo simulation was performed to evaluate the dosimetric contribution.
Methods: G...
Authors: Ashish Binjola, Raj Kishore Bisht, Natanasabapathi Gopishankar, Pratik Kumar, Daya Nand Kishore Sharma, Sukhvir Kishore Singh, Subramani Vellaiyan
Affiliation: Medical Physics Unit, All India Institute of Medical Sciences, All India Institute of Medical Sciences, Department of Radiological Safety, Institute of Nuclear Medicine and Allied Sciences, Department of Radiation Oncology, All India Institute of Medical Sciences
Abstract Preview: Purpose: Additive manufacturing is increasingly being explored to create dosimetry phantoms. Commercial anthropomorphic phantoms represent an average patient and lack anatomical variations due to obes...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...
Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University
Abstract Preview: Purpose: Multi-parametric MRI (mpMRI) is widely used for deep learning (DL)-based automatic segmentation of brain tumors. While multi-contrast images concatenated as channels are typically input to ne...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the “MyOSL Chip” OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang
Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology
Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...
Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago
Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...
Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Adam Leon Kesner, Cameron B. Kofler, Juan Camilo Ocampo Ramos, Yitian Wang, Stefan Wehmeier
Affiliation: University of Chicago, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson
Abstract Preview: Purpose: To develop a slice-specific computed tomography (CT) organ dose library using Monte Carlo radiation transport simulations on a newly created set of newborn, infant, and toddler computational ...
Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller
Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration
Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...
Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer
Affiliation: RaySearch Laboratories, Moffitt Cancer Center
Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...
Authors: Gayoung Kim, Junghoon Lee
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University
Abstract Preview: Purpose: 3D time-of-flight magnetic resonance angiography (TOF-MRA) is widely used for visualizing cerebrovascular structures. Accurate segmentation of cerebrovascular structures is critical for relia...
Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo
Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...
Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...
Authors: Chang Heon Choi, Minjae Choi, Yoonsuk Huh, Jin Jegal, Jung-in Kim, So-Yeon Park
Affiliation: Department of Radiation Oncology, Veterans Health Service Medical Center, Department of Radiation Oncology, Seoul National University Hospital
Abstract Preview: Purpose: Total Body Irradiation (TBI) aims to achieve a uniform dose distribution across the entire body. However, in conventional TBI setups that use extended source-to-surface distance (SSD) and lea...
Authors: Kaelyn Becker, Xenia Ray
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: Ethos 2.0 with HyperSight (Varian Medical Systems) imaging enables nearly fully automated offline adaptive radiotherapy including automated deformation of targets and recalculation on the Hou...
Authors: Justus Adamson, Wesley Andrew Cunningham, Chang-Sei Kim, Yeongoh Ko, Anna E. Rodrigues
Affiliation: Duke University, Chonnam National University, Duke University Medical Center
Abstract Preview: Purpose: Radiation induced toxicities in bowel remains a challenge for SBRT. Due to sharp dose falloffs, small displacements of the bowel can lead to meaningful dose reduction. Remote magnetic navigat...
Authors: Dylan Richeson, Dorin A. Todor
Affiliation: Inova Schar Cancer Institute, Virginia Commonwealth University
Abstract Preview: Purpose: High dose-rate (HDR) brachytherapy is prone to errors that can lead to incorrect dose delivery and potential medical events. One common issue is applicator length discrepancies, either due to...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey
Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...
Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez
Affiliation: University of Miami
Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...
Authors: Theodore Higgins Arsenault, Kyle O'Carroll, Christian Erik Petersen, Alex T. Price, Meiying Xing
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To assess the performance of various supervised learning models’ ability to predict binary classification of radiomic data for head and neck (H&N) cancer treatment outcomes.
Methods: Using...
Authors: Michael Ashenafi, Nicholas Becerra Espinosa, Mario Ramos Gallardo, Matthew Pacella, Sean M. Tanny
Affiliation: Department of Radiation Oncology, University of Rochester
Abstract Preview: Purpose: The newest version of a large commercial treatment planning system (TPS) has introduced a new physical MLC model. We compare the impact of using an averaged dosimetric leaf gap (DLG) value ve...
Authors: Darwin Abraham Garcia, Michael P. Grams, Scott C Lester, Maryam Mashayekhi, Douglas John Moseley, Robert W Mutter, Sean S Park, Chrystian Quintero Mateus
Affiliation: Mayo Clinic - Rochester, Mayo Clinic
Abstract Preview: Purpose: MBRT delivers sub-millimeter wide regions of high “peak” (~10s Gy) and low “valley” (~1 Gy) doses to treat cancer. MBRT commissioning is performed in flat, uniform plastic water. Thus, differ...
Authors: Yunzhi Ma, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: Multiple layers of brass mesh bolus (RPD, Inc., Albertville, MN) may be needed to provide better body conformity and sufficient dose build up on patient surface during electron treatment. Thi...
Authors: Gweneth Andersen, Colleen M. Foote, David (Bo) McClatchy, Hannah McFarland
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantify the impact of MLC model differences and LINAC age on treatment plan evaluation by log file-based patient-specific QA (PSQA) through the lifetime of the machines.
Methods: 3D ga...
Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding
Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington
Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Wen C. Hsi, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Measurement-based patient-specific quality-assurance (PSQA) conducted with a 2D dosimeter to verify delivered dose of each field over 3 measurement-depths is time-consuming with limited se...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
Treatment planning for intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) relies on inverse planning, an iterative and non-intuitive process of adjust...
Authors: Michelle Alonso-Basanta, Carl Denis, Wenbo Gu, Xinmin Liu, Ahmad Sakaamini, Rodney D. Wiersma
Affiliation: UCLA, University of Pennsylvania, CDR Systems
Abstract Preview: Purpose: Stereotactic radiosurgery (SRS) is a non-invasive technique used to treat functional abnormalities and small brain tumors. Traditional SRS relies on a rigidly fixed metal head ring, causing d...
Authors: Cheng-En Hsieh, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu, An-Ci Yang
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose:
The aim of this study is to develop a framework of generating patient-specific phantom tailored for head and neck proton therapy. From these phantoms, digital reference objects based on th...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: Ulrike Dydak, Chia-Tien Hsu, Chang Geun Lee, Cora Mizimakoski, Humberto Monsivais, Jae Hong Park
Affiliation: Purdue University
Abstract Preview: Purpose: Overexposure to manganese (Mn) from inhaling welding fumes can lead to cognitive and motor deficits. We developed a whole-brain Mn-mapping approach to detect subtle but significant increases ...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Nicole C. Detorie, Steven M. Kirsner, Remy Y. Manigold
Affiliation: Scripps Cancer Center
Abstract Preview: Purpose:
Dosimetric Leaf Gap (DLG) is an important factor in obtaining the proper beam model in the Eclipse treatment planning system. The purpose of this study was to investigate the dosimetric im...
Authors: William N. Duggar, Amirhossein Eskorouchi, Haifeng Wang
Affiliation: Mississippi State University, University of Mississippi Medical Center
Abstract Preview: Purpose:
Extracapsular extension (ECE) in lymph nodes represents a critical prognostic factor in head and neck squamous cell carcinoma (HNSCC), bearing important implications for staging, treatment...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
This study aims to leverage large language model (LLMs) to develop a human-in-the-loop agentic framework, enhancing the efficiency of treatment planning in radiotherapy.
Methods:
A L...
Authors: Christopher P. Favazza, Andrea Ferrero, Taylor Froelich, Forrest Linch, Scott Thompson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Photon counting detector (PCD) CT is a promising tool to enhance pre-procedural planning and intra-procedural guidance for prostate artery embolization due to its unsurpassed ultra-high spati...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, D. Michael Lovelock, Charlotte Elizabeth Read, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for precise motion management in MRI-guided radiotherapy (MRIgRT). While 2D Cine MRI offers high temporal resolution for motion tracking, it inherently l...
Authors: Jiayi Chen, Shaolei Li, Fuhua Yan, Yingli Yang, Jie Zhang
Affiliation: Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai United imaging Healthcare Advanced Technology Research Institute, Department of Radiation Oncology, Ruijin Hospital
Abstract Preview: Purpose: The aim of this exploratory study is to investigate the feasibility of establishing a model to explore tissue component heterogeneity using multidimensional diffusion magnetic resonance imagi...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Darren M. C. Poon, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study investigates optimal treatment strategies utilizing MR-linac for extremity lesions, with a specific focus on a 0.6 cm deep lesion in the right palm. The magnetic field-induced dose...
Authors: Rachel B. Ger, Heng Li, Anh Tran
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients undergo quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and utilize robustness scenarios for setup and range uncertainties. For intra...
Authors: Malvern Madondo, Mark McDonald, Zhen Tian, Christopher Valdes, Ralph Weichselbaum, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Emory University, Department of Radiology, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Head-and-neck (HN) cancer patients often experience significant anatomical changes during treatment course. Proton therapy, particularly intensity-modulated proton therapy (IMPT), is sensitiv...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Michael Bowers, Patrik Brodin, Madhur Garg, Rafi Kabarriti, William P. Martin, Todd R. McNutt, Julie Shade, Wolfgang A. Tomé, Christian Velten
Affiliation: Johns Hopkins University, Oncospace, Inc., Montefiore Medical Center
Abstract Preview: Purpose: Development of an automated planning tool utilizing AI generated patient-specific dose-volume histogram predictions for rapid H&N plan generation.
Methods: Planning best-practices were dev...
Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROC’s proton phantom program.
Methods: IROC’s proton QA program has six proton...
Authors: Abdullah Hidayat, Wazir Muhammad
Affiliation: Florida Atlantic University
Abstract Preview: Purpose: This study aims to predict Head and Neck cancer using an artificial neural network (ANN) through readily available basic health data. The goal is to uncover hidden patterns and predictors in ...
Authors: James L. Giltz, Michael J. Merrick
Affiliation: Alyzen Medical Physics, University of Kentucky
Abstract Preview: Purpose: To evaluate the capability of MyQA SRS in performing high-resolution machine QA to verify multileaf collimator (MLC) behavior and integrity for adaptive radiotherapy (ART). This study demonst...
Authors: Casey C. Heirman, Kyle J. Lafata, Xiang Li, Breylon Riley, Jack B Stevens, Tammara Watts
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: To leverage quantitative fluorescence imaging and spatial transcriptomics for characterizing the spatial and molecular heterogeneity of the tumor microenvironment (TME) in HPV+ head and neck ...
Authors: William T. Hrinivich, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Volumetric modulated arc therapy (VMAT) planning is a computationally expensive process. In this work, we propose a reinforcement learning (RL) framework to automatically optimize dose rate a...
Authors: Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Edward L. Clouser, Yi Rong, Jun Tan, Jennifer Yan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
To identify planning techniques that consistently result in robust VMAT-TBI plans that allow for larger patient setup errors.
Methods:
Conventional planning method often results in p...
Authors: Gong Vincent Hao, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami, Ikuno Nishibuchi, Peiying Colleen Ruan, Daguang Xu, Dong Yang
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, NVIDIA
Abstract Preview: Purpose:
Accurate tumor segmentation in head and neck cancer is critical for effective treatment planning, but variability in practices across medical facilities poses challenges for standardizatio...
Authors: Nuraddeen Nasiru Garba, Kalpana M Kanal, Abdullahi Mohammed, Rabiu Nasiru, Muhammad SHAFIU Shehu, Daniel Vergara, Joseph Everett Wishart
Affiliation: AHMADU BELLO UNIVERSITY, ZARIA, University of Washington
Abstract Preview: Purpose: To establish local Diagnostic Reference Levels (DRLs) for head and neck computed tomography (CT) exams in Abuja, Nigeria, and to investigate the performance of brain metastasis (BM) and brain...
Authors: Andrew Groll, Ayan Mitra, PhD, Manoj Narayanan, Sanchit Sharma, Ray Yang, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: To develop a versatile QA tool enabling dose recalculation of a patient’s plan sinogram redeployed onto arbitrary replacement phantom geometry, and extract computed dose along detector planes...
Authors: Petr Bruza, Yao Chen, David J. Gladstone, Lesley A Jarvis, Brian W Pogue, Kimberley S Samkoe, Yucheng Tang, Shiru Wang, Rongxiao Zhang
Affiliation: NVIDIA Corp, Dartmouth College, Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, University of Missouri, University of Wisconsin - Madison
Abstract Preview: Purpose: Cherenkov imaging provides real-time visualization of megavoltage radiation beam delivery during radiotherapy. Patient-specific bio-morphological features, such as vasculature, captured in th...
Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk
Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center
Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...
Authors: Yunfeng Cui, Joseph P. Kowalski, Qiuwen Wu, Yibo Xie
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: A Varian Ethos/Halcyon linac was recently commissioned in our clinic and was used to treat head and neck cancer patients. The purpose of this study is to compare treatment plan quality and de...
Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Demonstrating the feasibility of dose escalation for stereotactic recurrent head and neck (RHN) cancers through the deployment of a Hyper-Arc Based RapidPlan (HARP) model through an Eclipse S...
Authors: Lu Jiang, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Conventional radiotherapy treatment planning is guided by a set of generic objectives that are unspecific to patient anatomy. Treatment planning thus heavily relies on the planner’s experi...
Authors: Claus Belka, Stefanie Corradini, Christopher Kurz, Guillaume Landry, Matteo Maspero, Adrian Thummerer, Erik van der Bijl
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Radboud University Medical Center, UMC Utrecht
Abstract Preview: Purpose: To automatically harmonize non-standardized organ-at-risk (OAR) structure names from multi-lingual, multi-institutional radiotherapy datasets using state-of-the-art open-source reasoning larg...
Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray
Affiliation: University of California San Diego
Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Sarah Huo, David Zander, Wei Zhou
Affiliation: Cherry Creek High School, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
Ring artifact is commonly seen in CT, and it is usually caused by detector element failure or miscalibration. Although many ring artifacts are apparent and easy to recognize, those origina...