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Results for "spr curves": 15 found

BEST IN PHYSICS MULTI-DISCIPLINARY: Quantitative MRI Oximetry: Combining EPR and OE-MRI for Volumetric Mapping of Hypoxia in Tumors

Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Sergey V. Petryakov, Conner Ubert

Affiliation: Dartmouth College

Abstract Preview: Purpose: Tumor hypoxia—a state of reduced oxygen supply—is well known to affect treatment response, particularly in radiotherapy and chemotherapy. Oxygen-enhanced magnetic resonance imaging (OE-MRI) u...

BEST IN PHYSICS THERAPY: Overcoming Challenges in Developing Machine Learning-Driven Acute Kidney Injury Predictive Models Using Non-Standard Emrs in Resource-Limited Settings

Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou

Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, People’s Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital

Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...

Can Contrast Scans of Dual-Layer Detector Spectral CT be Directly Used for Proton Dose Calculations?

Authors: Wen C. Hsi, Pouya Sabouri, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
Traditional single-energy CT (SECT) contrast scans cannot be used for proton dose calculations due to significantly higher HU caused by iodine. Dual-layer dual-energy CT (DL-DECT) can dire...

Characterization of HCC Tumor Response in 90Y-Radioembolization Clinical Trial RAPY90D Using Prospective Voxel Dosimetry

Authors: E Courtney Henry, Srinivas Cheenu Kappadath, Armeen Mahvash

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Characterization of hepatocellular carcinoma (HCC) tumor responses for single-arm single-center prospective 90Y-radioembolization clinical trial (n=40) that used patient-specific voxel-dos...

Clinical Implementation of a Film Based Psqa System for SBRT on a 1.5T MR-Linac

Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal

Affiliation: Sunnybrook Health Sciences Centre

Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...

EPR Oximetry for Hypoxia Assessment in Deep Tissues Using Oxytrack

Authors: Maciej M. Kmiec, Periannan Kuppusamy, Ryan C. O'Connell, Sergey V. Petryakov, Conner Ubert

Affiliation: Dartmouth College

Abstract Preview: Purpose: The rigid needle-like EPR sensor, OxyTrack, was developed to provide minimally invasive, reliable, and quantitative measurements of oxygen distribution (pO2) in deep tissues. EPR oximetry's c...

Enhanced Predictive Model for Toxicity and 3-Year Survival in HCC Patients Using Learning Health System Infrastructure and AI-Driven Statistical Profiling

Authors: Ameer Elaimy, Theodore Lawrence, Charles S. Mayo, Seyyedeh Azar Oliaei Motlagh, Benjamin S. Rosen

Affiliation: University of Michigan

Abstract Preview: Purpose: To analyze the impact of clinical features on short-term survival, toxicity, and poor outcomes in HCC patients treated with SBRT,using automated data aggregation and enhanced algorithms with ...

Evaluating the Impact of Reconstruction Algorithm on Wide-Angle Digital Breast Tomosynthesis System Optimization for Microcalcification Detection

Authors: Xiaoyu Duan, Xinyu Hu, Runqiu Li, Xiang Li

Affiliation: Dukekunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
Accurate detection of small-sized microcalcifications (μCalcs) (< 500 µm) is critical for early breast cancer diagnosis, requiring optimal imaging systems and reconstruction algorithms. Ho...

Integrating Radiomics and ADC Ratio for Multicenter Prostate Cancer Diagnosis: A Harmonized Machine Learning Approach

Authors: George Agrotis, Marios Myronakis, Dimitrios Samaras, Kyriaki Theodorou, Ioannis Tsougos, Vassilios Tzortzis, Maria Vakalopoulou, Alexandros Vamvakas, Aikaterini Vassiou, Marianna Vlychou

Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Radiology, University of Thessaly, Netherland Cancer Institute, Department of Urology, University of Thessaly, CentraleSupelec, University Paris-Saclay

Abstract Preview: Purpose: Prostate cancer (PCa) diagnosis remains challenging due to discrepancies in Gleason Scoring (GS) and risks of overdiagnosis and underdiagnosis. Multiparametric MRI (mpMRI), including Apparent...

Predicting Hormone Receptor Status in Breast Cancer Using Mammographic and Sonographic Data and Machine Learning Models

Authors: Zahra Bagherpour, Manijeh Beigi, Pedram Fadavi, Faraz Kalantari, Moghadaseh Khaleghibizaki, Hengameh Nazari, Mojtaba Safari, Sepideh Soltani

Affiliation: Department of Radiation Oncology, School of Medicine, Iran University of Medical Sciences, Department of Radiation Oncology, School of Medicine, Emory University and Winship Cancer Institute, Department of Radiation Oncology, Iran University of Medical Sciences, University of Arkansas for medical sciences, Department of Radiation physics, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: This study aims to evaluate whether readily available mammographic and sonographic data, combined with machine learning (ML) models, can predict critical molecular factors (ER, PR, HER2) in b...

Predicting Pathological Complete Response to Neoadjuvant Chemotherapy for Breast Cancer at Early Time Points Using a Two-Stage Dual-Task Deep Learning Strategy

Authors: Bowen Jing, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Medical images acquired at multiple time points during neoadjuvant chemotherapy allow physicians to assess patients’ responses and personalize treatment plans accordingly. Studies from the I-...

Spatially Aware Radiomics Integrating Anatomical Knowledge to Improve Lymph Node Malignancy Prediction in Head and Neck Cancer

Authors: Liyuan Chen, Sepeadeh Radpour, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Accurate lymph node malignancy prediction is pivotal in optimizing radiation treatment strategies for head and neck (HN) cancer patients. While conventional radiomics models leverage intensit...

Task Specific Image Quality Assessment Using Spectral Photon-Counting CT.

Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq

Affiliation: Khalifa University

Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...

Validation of Updated CT-to-SPR Calibration Method with Icrp-145 Data for Carbon-Ion Radiotherapy

Authors: Min Cheol Han, Soorim Han, Chan Hyeong Kim, Jin Sung Kim, Seok-Ho Lee, Gahee Son, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: The stoichiometric calibration method proposed by Kanematsu et al. (2016) has been widely adopted for CT number to stopping-power ratio (SPR) conversion in carbon-ion radiotherapy. With the r...

Voxel-Based Radiobiological Modelling for Evaluating Radiotherapy Treatment Plans in Relation to Radiation-Induced Acute Mucosal Toxicity (including oral and pharyngeal mucositis): A Single-Institutional Study Focused on Head-and-Neck Carcinoma.

Authors: Rama Bhawani, Mary Joan, Ajay Katake, Munish Kumar, Chhape Ram, Megha Sharma, Balbir Singh, Vikram Singh

Affiliation: SLBSGMC & HOSPITAL, MOHANDAI OSWAL HOSPITAL, WOCKHARDT HOSPITAL, Christian Medical College and Hospital,, AMERICAN ONCOLOGY INSTITUTE

Abstract Preview: Purpose: This study aims to evaluate the utility of voxel-based radiobiological modelling in assessing IMRT radiotherapy treatment plans concerning radiation-induced acute mucosal toxicity, specifical...