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Results for "stage nsclc": 10 found

A Window-Level Based Approach for Generating Missing Tissue in CT Scans Using a Transformer-Gan Model

Authors: Mojtaba Behzadipour, Siyong Kim, Mitchell Polizzi, Richard R. Wargo, Lulin Yuan

Affiliation: VCU Health - Department of Radiology, Virginia Commonwealth University

Abstract Preview: Purpose:
The purpose of this study is to develop a method for generating missing tissue in CT scans of patients with large body sizes, where the field of view (FOV) of the scanner fails to capture ...

Development of a Knowledge-Based Planning Model for Optimal Trade-Off Guidance in Locally Advanced Non-Small Cell Lung Cancer

Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...

Exploring NSCLC Microenvironments: Multi-Score Survival Models Integrationg Radiomics-Based Regional Imaging Features and Genomics

Authors: Nobuki Imano, Daisuke Kawahara, Misato Kishi, Yuji Murakami

Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University

Abstract Preview: Purpose: This study aims to develop a comprehensive Multi-score by integrating Radiomics-score (Rad-score), Gene-score derived from gene expression levels, and tumor environment Rad-score (TE-Rad-scor...

Improving Post-SRS Brain Metastasis Radionecrosis Diagnosis Accuracy Via Deep Feature Space Analysis

Authors: Evan Calabrese, Scott R. Floyd, Kyle J. Lafata, Zachary J. Reitman, Eugene Vaios, Chunhao Wang, Lana Wang, Deshan Yang, Zhenyu Yang, Jingtong Zhao

Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University

Abstract Preview: Purpose:
This study proposes a novel neural ordinary differential equation (NODE) framework to distinguish post-SRS radionecrosis from recurrence in brain metastases (BMs). By integrating imaging f...

In-Silico Clinical Trials Enabled By Digital Twin Approach Can Accurately and Prospectively Predict Outcomes of Clinical Trials Combining Radiation and Systemic Therapy

Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital

Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...

Innovative Deep Learning Network for Overall Survival Prediction for NSCLC: Outperforming Pre-Trained Models VGG16 and ResNet50

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...

Key Tumor Volume Zones for Advancing the Radiomics-Based Distant Recurrence Prediction

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...

Lymph Node Dose Is Associated with Immune Suppression and Poor Overall Survival in Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Authors: Ryan Gentzler, Xin He, James Larner, J.T. Morgan, Cam Nguyen, Wendy Stewart, Krishni Wijesooriya, Grant Williams

Affiliation: Department of Physics, University of Virginia, Department of Radiation Oncology, University of Virginia, Division of Hematology & Oncology, Department of Medicine, University of Virginia

Abstract Preview: Purpose: Some recent studies have shown Overall Survival (OS) of advanced-stage lung cancer patients treated with chemo-radiation therapy (CRT) is correlated with heart dose [1-5], while in other stud...

Maximizing Integrated Treatment Planning Tools to Increase Automation for X-Ray-Based Adaptive Lung Sabr

Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...

Two-Stage Clustering and Auto Machine Learning to Predict Chemoradiation Response in Tumor Subregions on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen

Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...