Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong
Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian
Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithmsâ (Radfo...
Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...
Authors: Xiu tong Lin, Tao Sun
Affiliation: Department of Radiation physics and technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the positioning accuracy and time efficiency of "Sphere-Mask" Optical Positioning System (OPS) and traditional laser light positioning method in breast cancer radiotherapy, and to ...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Alexandra Christensen, Timothy J. Hall, Ivan M. Rosado-Mendez
Affiliation: University of Wisconsin, Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: Quantitative ultrasound techniques based on the statistical analysis of speckle are currently being deployed commercially and clinically as sources of biomarkers associated with tissue micros...
Authors: Zhitao Dai
Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...
Authors: Sophie Bockel, Eric Deutsch, Frederic Dhermain, Ibrahima Diallo, Anh Thu Le, Elaine Limkin, Pauline Maury, Charlotte Robert, Killian Sambourg, Camilla Satragno, Cristina Veres, François de Kermenguy
Affiliation: Gustave Roussy, Département de radiothérapie, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique
Abstract Preview: Purpose:
To study the correlation between the dose to circulating lymphocytes as evaluated by the LymphoDose framework and the incidence of severe radiation-induced lymphopenia (sRIL) in patients t...
Authors: Richard J Barth, Brook Kennedy Byrd, Roberta DiFlorio-Alexander, Misty J Fox, Venkat Krishnaswamy, Keith D. Paulsen, Timothy B Rooney
Affiliation: Cairn Surgical Inc., Dartmouth Health, Thayer School of Engineering, Dartmouth Hitchcock Medical Center, University of Virginia Health, CairnSurgical Inc.
Abstract Preview: Purpose: Supine breast MRI enables precise surgical planning with demonstrated benefit in decreasing positive margin rates during BCS. However, acquiring supine breast MRI scans in a secondary imaging...
Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...
Authors: Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Nancy Y Lee, Anyi Li, Jung Hun Oh, Teeradon Treechairusame, Pengpeng Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To automatically monitor weekly anatomical changes of parotid glands during adaptive radiotherapy of head and neck cancers, systematically assess the relationship between parotid gland shrink...
Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson
Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...
Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins
Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC
Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patientsâ ...
Authors: David J. Gladstone, P. Jack Hoopes, David I Hunter, Brian W Pogue, Jacob Pierce Sunnerberg, Armin Tavakkoli
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Geisel School of Medicine, Dartmouth College
Abstract Preview: Purpose: The FLASH effect, characterized by normal tissue sparing under ultra-high dose rate (UHDR) radiation delivery, remains mechanistically unclear. This study investigated the relationship betwee...
Authors: Jean Bourbeau, Jim Hogg, Miranda Kirby, Meghan Koo, Kalysta Makimoto, Wan Tan
Affiliation: Montreal Chest Institute of the Royal Victoria Hospital, McGill University Health Centre, Toronto Metropolitan University, Centre for Heart Lung Innovation, University of British Columbia
Abstract Preview: Purpose: Chronic obstructive pulmonary disease (COPD) exacerbations are burdensome to patients and healthcare systems. CT imaging-derived measures of emphysema and airway remodeling have been shown to...
Authors: Lei Dong, Yin Gao, Taoran Li, Michael Salerno, Boon-Keng Kevin Teo, Melissa Vila
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: A novel solution, RapidArc Dynamic-RAD (Varian Medical Systems, Palo Alto, USA) has been implemented to integrate VMAT with modulation of IMRT-like static-angle ports, including use of a dyna...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the âMyOSL Chipâ OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: Mark E Artz, Jiyeon Park, Lori Rice, Mohammad Saki, Sanjeev Shukla, Michael Vieceli
Affiliation: University of Florida Health Proton Therapy Institute, Department of Radiation Oncology, University of Florida College of Medicine, UF Health Proton Therapy Institute, Department of Urology, University of Florida College of Medicine
Abstract Preview: Purpose: To investigate how varying levels of DNA repair mutations affect the LET sensitivity of prostate cancer cells.
Methods: The prostate cancer cell lines Du145 (low DNA repair mutations), PC3...
Authors: ISAAC Amoah, Jackie Austin, Charlotte Block, Kaylee Brilz, Dylan Bui, Andrew E. Ekpenyong, Jayce Hughes, Natasha Ratnapradipa, Sara Strom, Jacob Woolf
Affiliation: Creighton University
Abstract Preview: Purpose: Cancers of the brain and nervous system account for 1 in 100 cancer diagnoses in the US every year. Surgery, radiotherapy, and chemotherapy constitute the standard of care. For Glioblastoma (...
Authors: Tianyuan Dai, Zejun Jiang, Xiangyue Kong
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
This study aims to evaluate the reliability of SFRT-VMAT plan verification by comparing two QA methods: Portal Dosimetry (PD) and Delta4Âź.
Methods:
Preteatment QA was conducted for 1...
Authors: Laura A. Doyle, Amy S. Harrison, Allyson P Koecher, Jackson D Reeves, Lindsay B Romak
Affiliation: Christiana Care
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) is increasingly utilized in radiation oncology, allowing for transition away from permanent skin marks to SGRT-based daily treatment setup. Following i...
Authors: Angela Gathers, Christina Henson, Sakuntala Jagabattuni, Mark A. Newpower
Affiliation: University of Oklahoma HSC, Department of Otolaryngology, University of Oklahoma HSC, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A previous departmental study showed an increase in ototoxicity (hearing loss) rates in head & neck cancer (HNC) patients treated with Intensity Modulated Proton Therapy (IMPT) vs. x-ray radi...
Authors: Carri K. Glide-Hurst, Thomas M Grist, Kevin M. Johnson, Prashant Nagpal, Tarun Naren, Chase Ruff, Oliver Wieben, Jiwei Zhao
Affiliation: Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison, Department of Radiology, University of Wisconsin-Madison, Department of Medical Physics, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison
Abstract Preview: Purpose: Cardiotoxicity is a devastating side effect for thoracic radiotherapy (RT). Currently, standard RT imaging is insufficient to decouple cardiorespiratory motion, limiting substructure-specific...
Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. Göksel, Görkem O. GĂŒngör, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan
Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman Sönmez Oncology Hospital
Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...
Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo
Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...
Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...
Authors: Parker Anderson, Elizabeth L. Bossart, Jonathan Cyriac, Nesrin Dogan, Robert Kaderka, Yihang Xu
Affiliation: University of Miami, University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
Knowledge-based planning (KBP) can enhance the treatment planning process in cancer radiotherapy (RT). By training a KBP model with high-quality treatment plans developed by experts, dose-...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Michael H. Shang, Stephen Shang, Timothy R Williams
Affiliation: South Florida Proton Therapy Institute, SFPRF, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose:
Daily image guidance for head and neck intensity-modulated proton therapy (IMPT) presents significant challenges due to large target volumes and anatomical changes. Geometric deviations al...
Authors: Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Development of a novel spatially fractionated radiotherapy (SFRT) lattice deployment method featuring a large high-dose sphere at the tumorâs center, surrounded by smaller diameter spheres. W...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Decreased lymphocytes increase the risk of infections and other problems. Radiation exposure can cause the development of severe lymphopenia. In this study, we used a dynamic blood flow model...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Davide Brivio, Ivan M. Buzurovic, Thomas C. Harris, Desmond A. O'Farrell
Affiliation: Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Cervical cancer can be treated with a brachytherapy boost following external beam radiotherapy. One applicator option is the Advanced Gynecological Applicator "Venezia" (Elekta) hybrid, consi...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: James E. Bates, Benjamin Hopkins, Kirk Luca, Shadab Momin, Justin R. Roper, Soumon Rudra, Eduard Schreibmann, Bill Stokes, Tu Thi, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Swallowing dysfunctions after radiotherapy are caused by multiple factors yet are strongly associated with the irradiation of pharyngeal musculature due to its role in the initiation and comp...
Authors: Jennifer L. Dolan, Chengyin Li, Parag Parikh, Doris N. Rusu, Kundan S Thind
Affiliation: Henry Ford Health, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The time and resource demands of online Adaptive Radiation Therapy (ART) can limit its widespread clinical adoption and potentially impact patient throughput. To address this, we developed a ...
Authors: Larry A. DeWerd, Keith A. Kunugi, Autumn Rasmussen
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Ensuring the validity of the thermoluminescent dosimeter (TLD) response requires verifying that signal fadingâdefined by a reduction in stored signalâis well-known and corrected for under the...
Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...
Authors: Hania A. Al-Hallaq, Xuxin Chen, Anees H. Dhabaan, Elahheh (Ella) Salari, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
Radiomics image analysis could lead to the development of predictive signatures and personalized radiotherapy treatments. However, variations in delineation are known to affect hand-crafte...
Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...
Authors: Chia-Lung Chien, Wen C. Hsi, Romy Megahed, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
The dosimetric variations induced by inter-fractional anatomical changes in intensity-modulated proton therapy could impact the clinic outcomes for head-and-neck (HN) cancer patients. This...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding
Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington
Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...
Authors: Miguel Albaladejo, Ana Corbalan, Aitor Ortega, Vicente Puchades, David Ramos, Alfredo Serna-Berna, Jonattan Suarez
Affiliation: Hospital General Universitario Santa Lucia
Abstract Preview: Purpose:
Prostate SBRT treatments are frequently delivered using standard VMAT IGRT technique. The aim of this study is to test the feasibility of Ethos Artificial Intelligence (AI) prostate SBRT b...
Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Jianrong Dai, Jun Dang, Enzhuo Quan, Yong Sang, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital & Shenzhen Hospital / Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: The current conformity index (CI) formula is distorted for radiotherapy plans with multiple, non-enclosing targets. We redefined the volume of reference isodose (VTV) parameter in the CI form...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu
Affiliation: Willis Knighton Cancer Center
Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...
Authors: Max Chen, Sean Marquardt, Ben Yang, Kai Yang
Affiliation: Cary Academy, Massachusetts General Hospital, Winchester High School
Abstract Preview: Purpose: To analyze the impact of scanner model variation on the effective dose conversion factor (âk-factorâ), which is most commonly used for CT effective dose calculation.
Methods: The stand...
Authors: Jaydev K. Dave, Krzysztof R Gorny, Chunming Gu, Nicholas J. Hangiandreou, Gina K. Hesley, Myung-Ho In, Zaiyang Long, Aiming Lu, Christin A. TiegsHeiden
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
MR-guided focused ultrasound (MRgFUS) enables precise tumor ablation with real-time MR-thermometry guidance. Our practice is exploring the potential use of Feraheme (Ferumoxytol), a superp...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: George Agrotis, Marios Myronakis, Dimitrios Samaras, Kyriaki Theodorou, Ioannis Tsougos, Vassilios Tzortzis, Maria Vakalopoulou, Alexandros Vamvakas, Aikaterini Vassiou, Marianna Vlychou
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Radiology, University of Thessaly, Netherland Cancer Institute, Department of Urology, University of Thessaly, CentraleSupelec, University Paris-Saclay
Abstract Preview: Purpose: Prostate cancer (PCa) diagnosis remains challenging due to discrepancies in Gleason Scoring (GS) and risks of overdiagnosis and underdiagnosis. Multiparametric MRI (mpMRI), including Apparent...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka
Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...
Authors: Mark Anastasio, Hua Li, Zhuchen Shao
Affiliation: Washington University School of Medicine, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Automated semantic segmentation of cell nuclei in microscopic images is vital for disease diagnosis and tissue microenvironment analysis. However, obtaining large annotated datasets for train...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Luuk J Oostveen, Elsa Bifano Pimenta, Ioannis Sechopoulos, Alessandra Tomal
Affiliation: Radboud University Medical Center, University of SĂŁo Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de FĂsica Gleb Wataghin
Abstract Preview: Purpose: The study evaluated the accuracy and precision of lung nodule volume measurements, specifically solid nodules (SNs) and ground-glass opacities (GGOs) in different imaging settings.
Methods...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...
Authors: Waleed Mutlaq Almutairi, Ke Colin Huang, Vishwas Mukundan, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue
Affiliation: Purdue University, Indiana University School of Medicine, Department of Radiation Oncology, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, Purdue University, West Lafayette, Indiana, USA
Abstract Preview: Purpose:
This study aimed to develop a machine learning (ML) model for early prediction of chemoradiotherapy (CRT) response in order to enhance personalized treatment selection for oral or orophary...
Authors: Jin Sung Kim, Chanwoong Lee, Young Hun Yoon
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: Chest contrast-enhanced CT (CECT) serves as a valuable tool for cardiac imaging, but its lack of detailed anatomical visualization limits its utility in segmentation tasks. While CECT offers ...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati
Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...
Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas
Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...
Authors: Corentin Desport, Dominique Iacchetti, Nicolas Kien, Ramiro Moreno, Melodie Munier, Séléna Pondard
Affiliation: Fibermetrix, Alara Expertise, Alara Group
Abstract Preview: Purpose: To evaluate the efficiency of organ-based tube current modulation (OBTCM) in thoracic and abdominopelvic Computed Tomography (CT) for different radiology departments and manufacturers. This s...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate four rectal symptoms with the dose to rectum in patients, who received SBRT with Cyberknife for prostate cancer. Also, to fit those dosimetric and outcome data by using a normal ...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate two urinary symptoms with dose to bladder and urethra in patients who received SBRT with Cyberknife. Also, to use a normal tissue complication (NTCP) model to fit the dosimetric ...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study aims at performing a normal tissue complication probability (NTCP) modeling by fitting the doses to the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) stru...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...
Authors: Vikas Aragam, Edward Castillo, Richard Castillo, Yingxuan Chen, Yevgeniy Vinogradskiy, Lydia J. Wilson
Affiliation: Thomas Jefferson University, Emory University, University of Texas at Austin
Abstract Preview: Purpose: 4DCT-based ventilation imaging (4DCT-ventilation) has been innovatively applied in radiotherapy treatment planning to minimize doses to functional portions of the lung, known as functional av...
Authors: Michael Paul Barnes, Lana C. Critchfield, John J. DeMarco, Ellie Durussel, Nilendu Gupta, James Irrer, Peyton Jensen, Grace Gwe-Ya Kim, Cory S. Knill, Seng Boh Gary Lim, Justin K. Mikell, Jean M. Moran, Seyyedeh Azar Oliaei Motlagh, Mario Perez, Michael Pillainayagam, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Washington University School of Medicine in St. Louis, University of California San Diego, Royal North Shore Hospital, Calvary Mater Hospital Newcastle, Cedars-Sinai Medical Center
Abstract Preview: Purpose: EPIDs are widely used in linac QA due to their efficiency and accuracy. As EPIDs age, performance degradation may occur, potentially compromising reliability of EPID-based automated QA result...
Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer
Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...
Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu
Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinsonâs disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...
Authors: Angela Gearhardt, Stephen F. Kry, Christopher Ryan Peeler, Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: A growing number of radiation therapy (RT) patients have cardiovascular implantable electronic devices (CIEDs). Patients with CIEDs must be carefully managed because the devices are susceptib...
Authors: Yijian Cao, Sean T Grace, Marissa Joyce Vaccarelli
Affiliation: Northwell
Abstract Preview: Purpose:
This study investigates the dosimetric efficacy of significantly limiting gantry angles in prostate radiation therapy to as a promising strategy to maintain plan quality while enhancing ma...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Filament deposition modeling (FDM) 3D printers may utilize proprietary calibration methods inadequate for medical imaging. Proper techniques are necessary to achieve imaging uniformity standa...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Ă sa K. Carlsson Tedgren, Taran Hellebust, Antonio Herreros, Jacob Johansen, Christian Kirisits, Panagiotis Papagiannis, Mark J. Rivard, Frank-Andre Siebert, Frank Verhaegen, Javier Vijande, Jan Wiersma, Marisol de Brabandere, Ruud van Leeuwen
Affiliation: UKSH, Campus Kiel, Klinik fĂŒr Strahlentherapie (Radioonkologie), Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Radiation Physics, Department of Medicine and Health (IMH), Linköping University, Radiation Oncology Department, Hospital ClĂnic-Universitat de Barcelona, IDIBAPS, IFIC-UV, Radiation Oncology, Amsterdam UMC location University of Amsterdam, Department of Radiation Oncology, Radboud University Medical Center, Department of Oncology, Aarhus University Hospital, University Hospital Gasthuisberg, Dept. of Radiation Oncology, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Department of Radiation Oncology (MAASTRO), GROW â School for Oncology and Reproduction, Maastricht University Medical Centre+, Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Warren Alpert Medical School of Brown University
Abstract Preview: Purpose: This study, which was carried out by the GEC-ESTRO BRAPHYQS working group, reports the increasing divergence between clinical reference air kerma rate (RAKR) measurements and vendor-provided ...
Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...
Authors: Yunfeng Cui, Joseph P. Kowalski, Qiuwen Wu, Yibo Xie
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: A Varian Ethos/Halcyon linac was recently commissioned in our clinic and was used to treat head and neck cancer patients. The purpose of this study is to compare treatment plan quality and de...
Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Matthew D Blackledge, Christopher M. Nutting, Anju Mohanan Kaimal, Justine Tyler, Konstantinos Zormpas-Petridis
Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, The Institute of Cancer Research
Abstract Preview: Purpose: Swallowing dysfunction (dysphagia) is a common side effect of radiotherapy for oropharyngeal cancer, significantly affecting patient's quality of life. This study aims to investigate the rela...