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Results for "stereotactic body": 57 found

4π Non-Coplanar Stereotactic Body Radiation Therapy: Dosimetric Evaluation of VMAT Configurations in for Recurrent Head and Neck Tumors

Authors: Sixue Dong, Weigang Hu, Jiazhou Wang, Zhen Zhang

Affiliation: Fudan University Shanghai Cancer Center

Abstract Preview: Purpose: This study aimed to evaluate the dosimetric benefits and treatment efficiency of different beam configurations in 4π non-coplanar VMAT for SBRT in recurrent head and neck tumors

Method...

A Comparison of on-Isocenter Vs Off-Isocenter Planning for Lung SBRT on the Viewray Mridian

Authors: Nebi Demez, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Treatment plans on the ViewRay MRIdian are often planned with the target placed off isocenter due to the proximity of the bore to the patient, allowing for limited shifts. This is especially ...

A Dosimetric Investigation into the Potential of Aperture-Based Techniques to Improve the Clinical Outcomes of Single-Energy Proton Bragg Peak Flash Therapy for Ocular Cancers

Authors: Arpit M. Chhabra, J Isabelle Choi, Minglei Kang, Haibo Lin, Hang Qi, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Xingyi Zhao, Ajay Zheng

Affiliation: New York Proton Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose:
Pencil beam scanning (PBS) proton therapy effectively treats ocular cancer by minimizing exit doses to normal tissues. However, challenges remain in sparing nearby organs-at-risk(OARs). Ul...

A Ground Truth Label-Mediated Method for Improved Bone and Gas Cavity Definition for MRI-Guided Online Adaptive Radiotherapy Workflows Using Synthetic CT Images.

Authors: Benito De Celis Alonso, Braian Adair Maldonado Luna, Gerardo Uriel Perez Rojas, René Eduardo Rodríguez-Pérez, Kamal Singhrao

Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla

Abstract Preview: Purpose: Artificial Intelligence (AI)-generated synthetic CT (sCT) images can be used to provide electron densities for dose calculation for online adaptive MRI-guided stereotactic body radiotherapy (...

A Knowledge-Based Approach for High-Quality Accelerated Partial Breast Irradiation Using Stereotactic Body Radiotherapy

Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Allison Dalton, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li

Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: External-beam Accelerated Partial Breast Irradiation (APBI) using stereotactic-body radiotherapy (SBRT) is increasingly adopted as an alternative to whole-breast radiation, offering targeted ...

A Patient-Specific Approach to Surface Guided-DIBH SBRT Candidacy Using Surface Deformation Maps

Authors: Savannah Decker, Grace Gwe-Ya Kim, Laura Padilla

Affiliation: UC San Diego, University of California San Diego

Abstract Preview: Purpose: The success of surface-guided deep-inspiration breath-hold (SG-DIBH) treatments depends on accurate identification of suitable candidates. Sub-optimal patient selection can result in prolonge...

A Quantitative Analysis of Interplay Effects in IMPT for Lung Cancer SBRT: Comparing Two Machine Delivery Sequence Models

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao

Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...

A Real-Time Framework for Fiducial Tracking and Intrafraction Motion Assessment of Cyberknife in Stereotactic Body Radiation Therapy for Liver Cancer

Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao

Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...

A Robust Quantitative Metric for Optimal Beam Selection in Radiotherapy of the Peripheral Lung Lesions: A Crucial Step in Standardization of Lung SBRT

Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...

Advancing Ionizing Radiation Acoustic Imaging: A Deep Learning Approach for Denoising and Quantitative Reconstruction

Authors: Kyle Cuneo, Issam M. El Naqa, Dale W. Litzenberg, Yiming Liu, Xueding Wang, Lise Wei, Wei Zhang, Jiaren Zou

Affiliation: University of Michigan, H. Lee Moffitt Cancer Center

Abstract Preview: Purpose: To quantitatively map 3D dose deposition during radiotherapy, empowering real-time adaptive radiation treatment.

Methods: The research features reconstructing dose deposition from acou...

An Adaptive Radiotherapy Approach Sparing Preirradiated Critical Structures

Authors: Mohamed Bahaaeldin Mohamed Afifi, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Chang Ming Charlie Ma, Robert A. Price

Affiliation: Fox Chase Cancer Center, Radiological Sciences and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University.

Abstract Preview: Purpose: Reirradiation of recurrent cancer or a newly developed lesion in a proximal location poses a challenge for radiation treatments. This is occasionally encountered in many modern clinics and ef...

Assessing the Impact of Intrafraction Shifts on Critical OAR Doses in a Standardized Spine SBRT Program

Authors: Daniel A. Alexander, Anish Butala, Anthony Austin Kassaee, Neil Malhotra, Ian Messing, Gabrielle W Peters, Ryan M. Scheuermann

Affiliation: Department of Radiation Oncology and Applied Sciences, University of Pennsylvania

Abstract Preview: Purpose: Stereotactic Body Radiation Therapy (SBRT) for spinal metastases uses CBCT-based localization and highly conformal treatment delivery to increase the biologically equivalent dose to the targe...

Assessing the Need for Online Adaptive Prostate SBRT Using the MR-Linac

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...

Assessing the Potential of Remote Navigation Systems to Mitigate GI Toxicity in Abdominal SBRT

Authors: Justus Adamson, Wesley Andrew Cunningham, Caleb Logan Smith

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose: Radiation induced bowel toxicity is a persistent issue for abdominal Stereotactic Body Radiation Therapy (SBRT). Remote magnetic navigation systems (RMNS) have been developed for use in magne...

Auto-Segmentation Scripting to Generate Optimization Structures for Spine SBRT Planning

Authors: Jon Hansen

Affiliation: Washington University in St Louis

Abstract Preview: Purpose: Commercially available auto-segmentation software was utilized to generate institution-specific optimization structures for spine stereotactic body radiation therapy (SBRT). Implementation of...

Bayesian Mixture Modelling of Apparent Diffusion Coefficients from Whole-Body MRI Reveals Significant Changes in Metastatic Lesions Treated with Stereotactic Body Radiotherapy Compared to Untreated Controls

Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu

Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust

Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...

Benefits on Respiratory Gating Delivery of Lung SBRT

Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng

Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University

Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...

Consecutive Daily Fractions with Itv Boost Are Safe for Treating Central Non-Small Cell Lung Cancer Using Stereotactic Body Radiation.

Authors: Baher Elgohari, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Jeonghoon Park, Tyler Wilhite

Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, UPMC, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
To compare toxicity between consecutive-daily (QD) with every-other-day (QoD) delivery of lung stereotactic-body-radiation (SBRT) for central non-small-cell lung cancer (NSCLC).
Methods...

Determination of Optimal Surface Rois for Sgrt-Guided Dibh Treatment of Abdominal Cancer

Authors: Megan E. Daly, Ajay Fernandez, Ryan D. Hernandez, Soo Kyoung Kim, Arta Monjazeb, Minahal Naveed, Peter C. Park, Jotsna Singh, Payton H. Stone

Affiliation: UC Davis Cancer Center

Abstract Preview: Purpose: To identify optimal deep-inspiration breath-hold (DIBH) surface-guided radiotherapy (SGRT) regions of interest (ROIs) for abdominal stereotactic body radiation therapy (SBRT) treatments.
M...

Development of a Novel 3D-Printed Heterogeneous Phantom for Liver SBRT Dose Verification in Hepatocellular Carcinoma (HCC) Treatment.

Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav

Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)

Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...

Dosimetric Comparison of MR-Linac Vs. Cyberknife for Prostate Stereotactic Body Radiation Therapy

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...

Early GU Toxicity Prediction in Prostate SBRT Using Delivered Dosimetry Via Long Short-Term Memory Model

Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...

Effects of Enhanced Leaf Modeling on Single-Isocenter Multi-Target Stereotactic Radiosurgery Dose Accuracy

Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao

Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine

Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...

Enhancing Lung SBRT Planning Efficiency: A Template-Based Approach Using Chest Wall Overlapping Cases

Authors: Felicia Chu, Qiongge Li, Jian Liu

Affiliation: Inova Hospital, Brown University Rhode Island Hospital, Hofstra University Medical Physics Program

Abstract Preview: Purpose:
This study aims to enhance the efficiency of stereotactic body radiation therapy (SBRT) planning for lung cancer by developing and evaluating optimization templates derived from historical...

Enhancing Synthetic Pelvic CT Images from CBCT Using Vision Transformer with Adaptive Fourier Neural Operators

Authors: Rashmi Bhaskara, Oluwaseyi Oderinde

Affiliation: Purdue University

Abstract Preview: Purpose: This study proposes a novel approach to overcoming CBCT image quality limitations by developing an improved synthetic CT (sCT) generation method based on a CycleGAN architecture using Vision ...

Enhancing Urethral Visualization for Prostate SBRT Using Post-Void T2-Weighted Imaging on a Low-Field 0.35T MR-Linac System

Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...

Evaluating PET-Based Metrics to Identify Patients with Liver Metastases for Biology-Guided Radiotherapy

Authors: Girish Bal, Ke Colin Huang, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue

Affiliation: Purdue University, RefleXion Medical, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) uses real-time positron emission tomography (PET) signals to precisely direct radiotherapy beamlets. The success of BgRT planning and delivery relies on PET...

Evaluating the Adequacy of Planning Target Volume Margins in Lung Stereotactic Body Radiation Therapy: Assessment of Intrafraction Motion Using a Fiducial Marker

Authors: Rashmi Benda, Qinghao Chen, Shifeng Chen, Giovanni Lasio, Peter Olivieri, Huijun Xu, Junliang Xu, Byong Yong Yi, Baoshe Zhang, Jinghao Zhou

Affiliation: University of Maryland Baltimore Washington Medical Group, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center

Abstract Preview: Purpose:
We investigated if the patients receiving lung stereotactic body radiation therapy (SBRT) have adequate planning target volume (PTV) margins by evaluating the intrafraction motion using a ...

Evaluation of Daily Respiratory Pattern from a Single Free-Breathing Cone Beam CT Scan

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patients’ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...

Evaluation of MRI Distortion across a Multi-Site Health System and the Importance of MRI Distortion QA in Stereotactic Radiosurgery (SRS)

Authors: Emel Calugaru, Jenghwa Chang, Sean T Grace, Nicholas Harvey, Jessica Jung, Ching-Ling Teng

Affiliation: Northwell, Hofstra University, Hofstra University Medical Physics Program

Abstract Preview: Purpose: To evaluate the consistency of MRI distortion corrections across Northwell Health system and evaluate the necessity and importance of distortion QA for MRIs used for stereotactic radiosurgery...

Evaluation of Treatment Delivery Efficiency and Workflow Optimization in Prostate Stereotactic Body Radiation Therapy: A Comparative Study of C-Arm and O-Ring Linear Accelerators

Authors: Yijian Cao, Jenghwa Chang, Lyu Huang

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systems—Varian’s TrueBeam (C-arm) and Halcyon (O-ring)—for prostate Stereotactic Body Ra...

Evaluation of Treatment Planning Feasibility and Dosimetric Quality of the Reflexion™ X1 System for Complex Spinal Targets

Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose:
The RefleXion® X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...

Functional Liver Image Guided Radiation Planning Using MRI with a Contrast Agent

Authors: Kenneth L. Homann, Natalie A Lockney, Hong Zhang

Affiliation: Department of Radiation Oncology, Vanderbilt University Medical Center, Vanderbilt University Medical Center

Abstract Preview: Purpose: The aim of this study is to develop a treatment planning methodology utilizing liver functional imaging via contrast-enhanced Magnetic Resonance Imaging (MRI) in patients undergoing stereotac...

High-Fidelity Treatment Optimization for Online Adaptive Stereotactic Partial Breast Irradiation: Integrating Dose and Treatment Time Considerations

Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello

Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...

Impac of Respiratory Motion on Dosimetric and Biological Outcomes in Lung Cancer SIB-SBRT: A 4D Dose Calculation Approach

Authors: Xiangli Cui, Lingling Liu

Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences

Abstract Preview: Purpose:
Respiratory motion introduces substantial dose uncertainties in lung cancer radiotherapy, particularly affecting dose distribution in Simultaneous Integrated Boost-Stereotactic Body Radiot...

Impact of Lung Density on Plan Quality and Delivery Parameters in Lung Stereotactic Body Radiation Therapy (SBRT) Plans

Authors: David Chighvinadze, Indra J. Das, Jeremy D. Donaghue, Kevin Stephans, Gregory Videtic, Sugandima Weragoda, Ping Xia

Affiliation: Cleveland Clinic, Cleveland Clinic Sandusky, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Cleveland Clinic Fairview

Abstract Preview: Purpose:: Evaluate the impact of lung density variations on plan quality and delivery parameters in lung SBRT Plans.
Methods: For a hypothetical case with a real patient anatomy, three GTVs with vo...

Impact of Patient Setup Errors on the MR Linac-Based SBRT Treatment for Prostate Cancer

Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: In radiation therapy, patient setup errors have been a primary concern impacting dose delivery accuracy. A robust treatment plan is essential to mitigate these errors. This study aimed to eva...

Integrating Clinical Knowledge Via Llms for Precise Organ-at-Risk Segmentation in Pancreatic Cancer SBRT

Authors: Karyn A Goodman, Yang Lei, Tian Liu, Pretesh Patel, Jing Wang, Kaida Yang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study aims to improve organ-at-risk (OAR) segmentation in pancreatic cancer stereotactic body radiotherapy (SBRT) by integrating clinical guidelines into deep learning workflows. We use ...

Investigation into the Robustness of Spine Stereotactic Body Radiotherapy Plans to Patient Setup Errors

Authors: Yukio Fujita, Syoma Ide, Fumiki Ito, Kei Ito, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki, Riku Watanabe

Affiliation: Komazawa University Graduate School, Komazawa University, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

Abstract Preview: Purpose: Spine stereotactic body radiotherapy (SBRT) demands high precision due to the target's proximity to the spinal cord and steep dose gradients, which complicate treatment planning. Consequently...

Key Tumor Volume Zones for Advancing the Radiomics-Based Distant Recurrence Prediction

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

MR-Based Functional Liver Imaging and Dosimetry to Predict Albi Change Post-SBRT

Authors: Madhava Aryal, James M. Balter, Yue Cao, Daniel T Chang, Kyle Cuneo, Joseph R. Evans, Theodore Lawrence, John Rice, Randall K. Ten Haken, Lise Wei

Affiliation: University of Michigan, Department of Radiation Oncology University of Michigan

Abstract Preview: Purpose: This study aims to identify predictors of global liver function change measured by albumin-bilirubin (ALBI) score following stereotactic body radiation therapy (SBRT) in hepatocellular carcin...

Optimizing Lung SBRT Delivery: Role of Multiple Cbcts in Managing Intra-Fraction Motion

Authors: Anthony J. Doemer, Ian Gallagher, Yimei Huang, Jeff A. Riess, Kundan S Thind, Bo Zhao

Affiliation: Henry Ford Health

Abstract Preview: Purpose: Stereotactic body radiation therapy (SBRT) is commonly used for early-stage lung cancer. While pre-treatment CT captures some tumor motion, it may not fully represent intra-fraction motion du...

Prediction of Vertebral Compression Fracture after Stereotactic Body Radiotherapy for Spinal Metastases Using Clinical, Radiomic and Dosiomic Features

Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki

Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...

Ratoguide: Evaluation of AI-Driven Fully Automated Treatment Planning Support System for Lung SBRT

Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka

Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi

Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...

Retrospective Evaluation of Combined Photon SBRT and Radium-223 SPECT Based Radiopharmaceutical Therapy Tumor Dosimetry in Clinical Trial Patient Cases

Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang

Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill

Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...

Safety of Off-Axis Treatment for Selection of Optimal Beam Angles in SBRT of the Posteriorly Located Lung Lesions

Authors: Reza Farjam, Russell K Hales, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Optimal beam angles and off-axis isocenter selection are important to achieve high quality plan and collision-free delivery in stereotactic body radiotherapy (SBRT) of the posteriorly located...

Small Fields Output Factor Measurements in 1.5 MR-Linac

Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...

Stereotactic Body Radiosurgery for Refractory Ventricular Tachycardia: Presenting Efficient Clinic Workflow, Dosimetric Analysis and Patients Reported Clinical Results

Authors: Karam Ayoub, Aaron B Hesselson, Ronald C McGarry, Joshua Misa, Damodar Pokhrel

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Cardiology

Abstract Preview: Purpose: Noninvasive stereotactic body radiosurgery (SBRS) is emerging treatment option for advanced heart failure patients with refractory-ventricular tachycardia (rVT) who experienced recurrent impl...

Study of PSMA-PET/MR Biomarkers for Prostate Stereotactic Radiotherapy Planning

Authors: Guillermo Daniel Alvarez, Daniel Fino, Rocio Luz Gilli, Dorian Alexander Romero

Affiliation: School Foundation of Nuclear Medicine, INTECNUS Foundation, Nuclear Medicine and Radiotherapy Center of Southern Patagonia

Abstract Preview: Purpose: To evaluate the anatomical, functional, and molecular information from PET/MR images with F18-PSMA to identify intraprostatic lesions and delineate a boost in stereotactic body radiotherapy (...

Targeted Multi-Criteria Optimization for Rapid Improvement of Organ-at-Risk Dose in the Setting of Prostate Stereotactic Body Radiation Therapy

Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....

The Impact of Intempo Imaging on Cyberknife Prostate Plans

Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...

Three-Dimensional Reconstruction of Triggered Images with Dehazing Algorithm for Precise Intrafraction Motion Detection in Spine SBRT

Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University

Abstract Preview: Purpose: To precisely detect intrafraction patient motion during spine stereotactic body radiotherapy (SBRT) treatment delivery, we propose an optimized technique for three-dimensional reconstruction ...

Using the Liver Dome for Real-Time Respiratory Motion Adaptive Tracking in Cyberknife Stereotactic Body Radiotherapy (SBRT) for Lung Tumors

Authors: Hulya Ozdemir Buss, Julius G. Ojwang, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: The CyberKnife (CK) Synchrony system provides sub-millimeter motion-tracking accuracy during stereotactic body radiotherapy (SBRT). For lung tumors near the diaphragm, we evaluated the feasib...

Utilizing Bladder Ultrasound to Estimate on-Table Bladder Volume in Prostate Cancer SBRT: Impact on Treatment Setup Consistency and Dosimetric Outcomes

Authors: Minsong Cao, Amar Kishan, Dylan P. O'Connell, Jonathan Pham, Michael Steinberg, Luca F Valle, Michael Xiang

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: To evaluate bladder ultrasound as a surrogate for estimating on-table bladder volume in prostate cancer patients undergoing stereotactic body radiation therapy (SBRT). The study aimed to asse...

Validation of SRS Mapcheck for Patient-Specific Quality Assurance of Cyberknife

Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...

Whole Heart Sparing Ethos Adaptive Radiotherapy for Lung Cancer

Authors: Ibrahim Aref, David Bergman, Justine M. Cunningham, Payton Dolan, Aharon Feldman, Yimei Huang, Joshua P. Kim, Brett M. Miller, Emily Moats, Benjamin Movsas, Kundan S Thind

Affiliation: Henry Ford Health

Abstract Preview: Purpose: Cardiac radiation dose is directly associated with adverse cardiac events which are predictive of mortality in lung cancer patients. In fractionated lung radiotherapy, studies have shown a hi...