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Results for "structural changes": 9 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

BEST IN PHYSICS IMAGING: Population-Based Cardio-Respiratory Motion Model to Simulate 4D CT Angiography and 2D+t Fluoroscopy for Percutaneous Coronary Intervention

Authors: Debarghya China, Junghoon Lee, Ali Uneri

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins Univ

Abstract Preview: Purpose: This study aims to develop a population-based cardio-respiratory motion model and apply it to patient-specific 3D CTA to simulate 4D CTA and 2D+t fluoroscopy sequences. The developed motion m...

Brain Structural Covariance Networks in Nicotine-Dependent Users: A Graph Analysis

Authors: Humberto Monsivais, Brian A. Taylor, Francesco Versace

Affiliation: Purdue University, Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: To identify possible signatures of altered brain morphometry in nicotine-dependency via a structural covariance network approach.

Methods: Fifty-one healthy controls (HC:27M, mean age=...

Breathing New Life into Pulmonary Imaging: Development and Clinical Validation of an X-Ray Interferometry System

Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya

Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices

Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...

Can Regional Radiomic Features from Pre-Treatment Computed Tomography Serve As Biomarkers for Predicting Radiation Pneumonitis?

Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin

Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...

Enhancing T2-Weighted Brain MRI Resolution across Orientations Using AI-Based Volumetric Reconstruction

Authors: Mengqi Shen, Meghna Trivedi, Tony J.C. Wang, Andy (Yuanguang) Xu, Yading Yuan

Affiliation: Columbia University Medical Center, Dept of Med Hematology & Oncology, Data Science Institute at Columbia University, Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center

Abstract Preview: Purpose: T2-weighted (T2w) images are critical for identifying pathological changes due to their superior contrast in differentiating tissue types. However, they often lack detailed anatomical resolut...

Four-Dimensional on-Beam Computed Tomography Reconstruction from Projection Image Differences Representing Motion Change

Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon

Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester

Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...

Non-Invasive Photoacoustic Thermometry for Real-Time Monitoring of Tissue Temperature Using Frequency Analysis

Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar

Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University

Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...

Uprightvision: A Deep-Learning Toolkit for Transforming Supine Anatomy to Upright

Authors: Ming Dong, Carri K. Glide-Hurst, Behzad Hejrati, Joshua Pan, Yuhao Yan

Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Upright patient positioners and vertical CT reduce tumor motion and stabilize internal anatomy during treatment delivery. Yet, to fully exploit the advantages of upright, translation of stand...