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Results for "three four": 151 found

4D Monte Carlo Dose Evaluation for Mobile Targets in a Magnetic Field

Authors: Odunola Grace Babawale, B. Gino Fallone, Alireza Gazor, Andrei D. Ghila, Patricia A. K. Oliver, Michael W. Reynolds, Keith D. Wachowicz, Tania Rosalia Wood, Shima Y. Tari, Eugene Yip, Jihyun Yun

Affiliation: Nova Scotia Health, Dept. of Medical Physics and Dalhousie University, Dept. of Physics and Atmospheric Science, Dept. of Radiation Oncology, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com, Department of Medical Physics, Arthur J. E. Child Comprehensive Cancer Centre, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Department of Medical Physics, BC Cancer, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute

Abstract Preview: Purpose: To evaluate the dose to a moving target and its surroundings in a magnetic field using 4D-Monte-Carlo (MC) simulation.
Methods: The study utilizes a previously validated MC model of our li...

A Clinically Aligned Embedding Model for Glioma Prognostication Via Radiology-Pathology Report Matching

Authors: Steve Braunstein, Yannet Interian, Hui Lin, Bo Liu, Janine Lupo, Olivier Morin, Benedict Neo

Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Data Science, University of San Francisco, University of San Francisco

Abstract Preview: Purpose: Large Language Models (LLMs) demonstrate strong general text comprehension but remain limited in oncology due to insufficient contextual alignment. We pilot embedding alignment through radiol...

A Framework for Automated Selection of Dose-Volume Objectives to Improve Radiation-Induced Immune Suppression (RIIS)-Related Overall Survival (OS) Following Chemo-Radiotherapy

Authors: Gabriel Lucas Andrade de Sousa, Einsley-Marie Janowski, Cam Nguyen, Krishni Wijesooriya

Affiliation: Department of Radiation Oncology, University of Virginia, Department of Physics, University of Virginia

Abstract Preview: Purpose: Optimizing radiation therapy (RT) to spare the immune system may improve Overall Survival (OS) in cancer patients. This study develops a computational algorithm to identify optimal dose-volum...

A Method to Check the Consistency and Reproducibility of VMAT Delivery

Authors: Chloe Doen Kim, Patricia E. Lindsay, Bern Norrlinger, Jan P. Seuntjens

Affiliation: Princess Margaret Cancer Centre & University of Toronto, Queen's University, Princess Margaret Cancer Centre

Abstract Preview: Purpose: To propose a method to check the consistency of VMAT delivery on linear accelerator (LINAC) with a commercial three-dimensional array device. The method is insensitive to the correction facto...

A Modular Approach to Reversible and Stackable Medical Imaging Translation Models: CBCT-Based Synthetic MRI with Multiple U-Nets in Series (MUNETs)

Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang

Affiliation: Radiation Oncology, Keck School of Medicine of USC

Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...

A Motion Tracking Quality Assurance Platform for the Leksell Gamma Knife Hdmm System

Authors: Tsuicheng D. Chiu, Strahinja Stojadinovic, Aaron Thomlinson, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Design and develop an automated verification and validation platform for the Elekta Leksell Gamma Knife (GK) Icon/Esprit High-Definition Motion Management (HDMM) system.

Methods: The H...

A No-Reference Medical Image Quality Assessment Method Based on Automated Distortion Recognition Technology: Application to Preprocessing in MRI-Guided Radiotherapy

Authors: Jiayun Chen, Shengqi Chen, Yuan Tang, Zilin Wang, Guohua Wu, Jianan Wu

Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Abstract Preview: Purpose:
To develop a novel no-reference image quality assessment (NRIQA) method for evaluating the effectiveness of image preprocessing in MRI-guided radiotherapy (MRIgRT), thereby enhancing clini...

A Novel 3D Printed Template for Electron Treatments to Aid Patient Positioning and Targeting.

Authors: Christopher J. Mart, Inna V. McGowin

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: Electron treatments are prone to setup variations and uncertainties due to absence of imaging or surface guided alignment. Patient setup relies on daily marking and visual verification. A 3D-...

A Novel Cost-Effective Customizable 3D-Printed Thoracic Phantom for End-to-End Treatment Verification and Image Quality Assessment

Authors: Reza Farjam, Russell K Hales, Seth Jayawardane, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins School of Medicine

Abstract Preview: Purpose: This study presents a novel cost-effective customizable 3D-printed phantom developed for end-to-end treatment verification and image-quality assessment for thoracic applications.
Methods: ...

A Pilot Study to Implement a Definitive Breast SBRT Technique

Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal

Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre

Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...

A Practical Radiation Safety and Protection Training Program for Medical Physics Residents

Authors: Robert A. Rodgers

Affiliation: Vanderbilt University School of Medicine

Abstract Preview: Purpose: Medical Physics Graduate programs incorporate radiation safety and protection (RSP) into their curriculum. During Residency Program candidate interviews, didactic methods utilized by graduate...

A Quantitative Analysis of Hypersight CBCT Image Quality Using a Phantom-Based Approach Under Different Scatter Conditions

Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech

Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC

Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...

A Radiomic Quantification Framework for Hyperparameter Optimization in Texture Characterization

Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu

Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...

A Radiomics and Dosomics-Based Approach for Predicting Hematologic Toxicity in Patients with Cervical or Endometrial Cancer

Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma

Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...

A Risk Assessment Approach to Photon Reference Dosimetry Using TG-100 Methodology

Authors: Ila Farhang, Ryan D. Foster, Devin Heitz, Jordan B Lunsford, Ashkan Shafiee

Affiliation: Atrium Health Wake Forest Baptist, Atrium Health/LCI Cabarrus

Abstract Preview: Purpose: American Association of Physicists in Medicine (AAPM) Task Group (TG) -51 is a widely utilized protocol for the absolute calibration of linear accelerators. The purpose of this project was fo...

AI-Driven Quality Assurance for Gamma Camera/SPECT Anomaly Detection Using Contrastive Learning

Authors: Shanli Ding, Osama R. Mawlawi, Tinsu Pan

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Reliable detection of anomalies in Gamma Camera/SPECT flood images is vital for quality assurance (QA). Traditional methods relying on numerical thresholds and manual inspections often mis...

Adapting Newer Treatment Planning Strategy for Uveal Melanoma Cases Using Gamma Knife Radiosurgery

Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan

Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences

Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:

An Efficient Deep Learning Model with Multi-Scale Integration for Automated Pancreas Segmentation on MR Images

Authors: Jingyun Chen, Yading Yuan

Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology

Abstract Preview: Purpose: To develop and evaluate the Scale-attention network (SANet) for automated pancreas segmentation on MR images.
Methods: To develop SANet, we extended the classic U-Net design with a dynamic...

An Experimentally Derived Microscale Blood and Lymphatic Vasculature Model for Applications to Radiopharmaceutical Dosimetry

Authors: Peter Balogh, Wesley E. Bolch, Mir Md Nasim Hossain, Nien-Wen Hu, Walter Murfee, Wyatt Smither, Julia D. Withrow

Affiliation: New Jersey Institute of Technology, University of Florida

Abstract Preview: Purpose: To develop 3D computational, tissue-representative models incorporating physiologically relevant microvascular network patterns for calculating local alpha particle and electron dosimetry eff...

An Image Representation of Radiomics Data for Enhanced Deep Radiomics Analysis with Consideration of Feature Interactions

Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...

An Open-Access Toolkit to Generate Realistic CT and Low-Field MR Images Based on an Xcat Phantom

Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu

Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell

Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...

Application of a Flashdiamond Detector Coupled to a Beam Current Transformer to Commission a Monte Carlo Model of a Ultra-High Dose Rate Electron Beam

Authors: Javier Chiasson, Dominique Guillet, Arthur Lalonde, Karim Zerouali

Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal

Abstract Preview: Purpose:
To validate a Monte Carlo (MC) model of a Ultra-High dose rate (UHDR) electron beam using a prototype flashdiamond (fD) detector coupled to an electrostatically shielded beam current trans...

Assessing Low Iodine Concentrations in Liver Lesions with Dual Energy CT: Impact of Beam Choices

Authors: Xinhua Li, Vu Nguyen, Yifang (Jimmy) Zhou

Affiliation: Cedars-Sinai Medical Center

Abstract Preview: Purpose: Assessing iodine concentration in liver lesions is essential for evaluating contrast enhancement in multi-phase liver CT and for accurate disease diagnosis. This study aims to evaluate the as...

Assessing the Impact of Weighting Dose Volume Histograms By Variable Relative Biological Effectiveness for Radiation-Induced Lymphopenia Risk Prediction

Authors: Yan Chu, Madison Emily Grayson, Radhe Mohan, Pablo P. Yepes

Affiliation: UT Health Science Center at Houston, Rice University, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Radiation-induced lymphopenia (RIL) is a common adverse effect of radiation therapy, negatively impacting overall survival and anti-PD1 immunotherapy efficacy. Our lab previously developed a ...

Assessment of Off-Target Dose for Curative Treatment of Pregnant Head and Neck Cancer Case: A Monte-Carlo Study

Authors: Brianna Baek, David J. Carlson, Zhe (Jay) Chen, Dae Yup Han, Bon Tack Koo, Hyojun Park

Affiliation: Columbia University, Canyon Crest Academy, Department of Therapeutic Radiology, Yale University School of Medicine, Department of Radiation Oncology, Chung-Ang University Gwang Myeong Hospital

Abstract Preview: Purpose: To find an optimized treatment technique and shielding design for minimizing the dose to a fetus, a Monte-Carlo simulation was performed to evaluate the dosimetric contribution.
Methods: G...

Auto-Beam Hold Validation for Varian Sgrt Identify 3.0 on Truebeam Linear Accelerators

Authors: Hongyu Jiang, Wangyao Li, Dima Soultan, Fen Wang, Jun Xu

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: To validate the Auto-Beam Hold functionality via the MMI connection between Varian SGRT system IDENTIFY 3.0 and treatment linacs.
Methods: A treatment plan was created in the Eclipse TPS u...

Automated Framework for Predicting Tumour Growth in Vestibular Schwannomas Using Contrast-Enhanced T1-Weighted MRI

Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi

Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals

Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...

Automatic Specific Absorption Rate (SAR) Prediction for Hyperthermia Treatment Planning (HTP) Using Deep Learning Method

Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...

Automatic Tumor Segmentation and Catheter Detection from MRI for Cervical Cancer Brachytherapy Using Uncertainty-Aware Dual Convolution-Transformer Unet

Authors: Majd Antaki, Rohini Bhatia, Gayoung Kim, Yosef Landman, Junghoon Lee, Akila N. Viswanathan

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Physics and Advanced Development Elekta

Abstract Preview: Purpose: Brachytherapy is a standard radiation therapy approach for cervical cancer, which directly delivers radiation source to the tumor using catheters. Treatment planning requires identification o...

Bayesian Mixture Modelling of Apparent Diffusion Coefficients from Whole-Body MRI Reveals Significant Changes in Metastatic Lesions Treated with Stereotactic Body Radiotherapy Compared to Untreated Controls

Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu

Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust

Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...

Benefits on Respiratory Gating Delivery of Lung SBRT

Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng

Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University

Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...

CBCT Dose Measurement for Common Protocols on Elekta Versahd and Varian Truebeam

Authors: Yingxuan Chen, Jun Li, Alexis N. Webb

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: Cone-beam computed-tomography (CBCT) is widely used for image-guided therapy. Cumulative dose from repeated CBCT might be a concern. This study aims to measure and compare the CBCT dose for c...

CBCT-Based Radiomics of Head and Neck Cancer for Predicting Patient Toxicity to Radiotherapy

Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy

Affiliation: University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...

CNN-Based Reconstruction for 3D Scintillation Dosimetry of Proton Pencil Beams

Authors: Sam Beddar, Jason Michael Holmes, Daniel G. Robertson, James J. Sohn, Ethan D. Stolen

Affiliation: Department of Radiation Oncology, Mayo Clinic, MD Anderson Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago

Abstract Preview: Purpose: Camera-based scintillation dosimetry incorporating large volumes have shown promise for fast and comprehensive evaluation of external beam treatment fields. While some efforts have been made ...

Characterisation of Breathing Volumes and Surface Motion for Upright and Supine Treatment Positions

Authors: Sophie Boisbouvier, David Cobben, Anthony L Criscuolo, Michael W. Kissick, Mark Ramtohul, Gordon Sands, Tracy Underwood

Affiliation: University of Surrey, Department of Medical Physics, Queen Elizabeth Hospital, Lung Cancer and Sarcoma Radiotherapy, The Clatterbridge Cancer Centre, Leo Cancer Care, Radiotherapy department, Centre Léon Bérard

Abstract Preview: Purpose:
Pulmonary function tests (PFTs) help assess treatment options for lung cancer patients. Conventionally, these are undertaken upright, whereas radiotherapy is administered supine. This stud...

Characterizing the Stability of Upright CT for Proton Therapy

Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan

Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care

Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...

Clinical I-131 Dosimetry: Audit, Review, and Evaluation

Authors: Colin Adam Doyle, Celeste Winters

Affiliation: Department of Diagnostic Radiology, Oregon Health & Science University, School of Medicine, Oregon Health & Science University

Abstract Preview: Purpose: To audit our radioactive iodine (I-131) dosimetry protocol, review dosimetry methods used at other facilities, investigate the clinical impact of I-131 dosimetry at our facility, and test the...

Comparative Analysis of Four Measurement Methods for Multileaf Collimator Backlash

Authors: Niko Ahjoniemi, Antti Kulmala, Katja Peltola

Affiliation: Clinical Research Institute HUS, Helsinki University Hospital

Abstract Preview: Purpose: To determine the backlash of a multileaf collimator (MLC) using four measurement methods: motor encoder (primary readout), linear potentiometer (secondary readout), amorphous silicon panel (p...

Comparison of Optimized Magnetic Resonance Sequences in the Treatment Planning of Surface Brachytherapy

Authors: Ivan M. Buzurovic, Phillip M. Devlin, Evangelia Kaza, Michael John Lavelle

Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Recent work in surface brachytherapy (SBT) has demonstrated the feasibility of using magnetic resonance (MR)-guidance in place of Computer Tomography (CT) in SBT planning. The purpose of this...

Comparison of Ultra-High Resolution and Standard CT Imaging Modes for Small Vessel Visualization in Coronary CTA Using Photon Counting CT

Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich

Affiliation: Rush University

Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....

Comprehensive Evaluation of Federated Learning Strategies for Head and Neck Tumor Segmentation on PET/CT Images

Authors: Jingyun Chen, Yading Yuan

Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology

Abstract Preview: Purpose: To evaluate centralized and decentralized strategies for federated head and neck tumor segmentation on PET/CT.
Methods: We utilized training data from the HEad and neCK TumOR segmentation ...

Contrast-Free Full Intracranial Vessel Geometry Estimation from MRI with Metric Learning-Based Inference

Authors: Zhaoyang Fan, Eric Nguyen, Dan Ruan, Jiayu Xiao

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of Southern California, University of Southern California

Abstract Preview: Purpose: MR vessel wall imaging (VWI) has been shown to be effective for evaluating intracranial atherosclerosis disease. However, VWI typically also requires an MR angiography (MRA) in the same imagi...

Design and Implementation of a Dedicated Ethics and Professionalism Course for a Campep Accredited Graduate Program in Medical Physics

Authors: Jenghwa Chang, Marissa Joyce Vaccarelli

Affiliation: Northwell, Hofstra University Medical Physics Program

Abstract Preview: Purpose: Our University has a CAMPEP-accredited Master of Science (MS) in Medical Physics program with an established curriculum. Prior, ethics and professionalism themes were taught in an introductor...

Design and Use of a Modified Commercial Phantom for Gamma Knife End-to-End Testing

Authors: Edward A. Opalko, Matthew B. Podgorsak, Dheerendra Prasad

Affiliation: Roswell Park Comprehensive Cancer Center

Abstract Preview: Purpose: To design a 3D printed insert for Varian’s SRS Head Phantom that allows for multi-planar film dosimetry and to evaluate its ability in end-to-end testing for Gamma Knife treatments.
Method...

Determine the Isocenter and Its Size for MR Linac Unity Part1: (U V) of Cax

Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang

Affiliation: NYU Langone Health

Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...

Developing Metrics for Evaluating Machine Matching across Elekta Linear Accelerators in a Multicenter Clinic

Authors: Ashley Elizabeth Bonner, Michael G. Snyder

Affiliation: Corewell Health William Beaumont University Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital

Abstract Preview: Purpose: Develop and evaluate metrics for assessing beam matching of profiles across Elekta linacs in a multisite clinical setting.
Methods: Four Elekta linear accelerators (three VersaHD and one A...

Development of a Comprehensive Thoracic Re-Irradiation Database and Investigation of Time-Dependent Dose-Recovery Dynamics for Toxicity Modeling

Authors: Victoria Doss, Tsion Gebre, Rachel B. Ger, Esi A Hagan, Elaina Hales, Russell K Hales, Xun Jia, Heng Li, Dezhi Liu, Todd R. McNutt, Meti Negassa, Anas Obaideen, Tinker Trent, K. Ranh Voong, Cecilia FPM de Sousa

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: As cancer care advances, more patients require re-irradiation, yet evidence-based data is lacking. This study aimed to develop a thoracic re-irradiation database and explore time-dependent re...

Developments of a Low-Cost Multi-Target Winston-Lutz Phantom and Software for SRS Linac Machines

Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma

Affiliation: University of Pennsylvania, Mayo Clinic

Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...

Diffusion Model-Based Motion Correction in Portable Computed Tomography for Brain: Human Observer Study

Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...

Diffusion-Weighted MRI: An Early Biomarker for Treatment Response in MR-Guided Treatment of Rectal Cancer

Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...

Direct-to-Unit Dose Calculations for Stereotactic Radiosurgery on a C-Arm Linac with Modern on-Board Imaging Solutions

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Haley K Perlow, Alex T. Price, Atefeh Rezaei, Prashant Vempati, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: The HyperSight imaging feature on C-arm linacs(HS-CBCT) offers increased CT number accuracy over conventional on-board imaging. The C-arm geometry allows for noncoplanar treatments common to ...

Dose Evaluation of Multiple Gammatiles in Heterogeneous Brain Models Using Egs_Brachy

Authors: Fatemeh Akbari, Artemis Dalby, Nelson A. Miksys, Prarthana Pasricha, Rowan M. Thomson

Affiliation: Ackerman Cancer Center, Carleton University

Abstract Preview: Purpose: To investigate dose evaluations for GammaTile brachytherapy, a novel treatment for brain malignancies. The analysis focuses on the impact of tissue heterogeneities, including the presence of ...

Dosimetric Assessment of Simultaneous Multi-Energy and Fluence Optimization for IMRT and VMAT

Authors: Aliasghar Rohani, Rui Zhang

Affiliation: Louisiana State University, Baton Rouge, Louisiana, Department of Radiation Oncology, Mary Bird Perkins Cancer Center

Abstract Preview: Purpose: This study aimed to evaluate the impact of simultaneous optimization of multi-photon beam energy and fluence on IMRT and VMAT treatment planning.
Methods: An Elekta linear accelerator (lin...

Dosimetric Uncertainties Associated with Photon Small Field Dosimetry

Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West

Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma

Abstract Preview: Purpose: To evaluate quantitatively the dosimetric uncertainties associated with dose calculation and measurement of small photon fields used in stereotactic photon therapy.
Methods: The output fac...

Energy Dependency of Biological Effects from Radiation Scattering Around Medical Implants in Particle Therapy

Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum

Affiliation: Osaka University, Texas A&M University

Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...

Enhanced Prognostic Modeling for Clear Cell Renal Cell Carcinoma Via Multi-Omics Model and Computational Pathology Foundation Model Integration

Authors: James Brugarolas, Meixu Chen, Raquibul Hannan, Payal Kapur, Jing Wang, Kai Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Accurate prognosis of clear cell renal cell carcinoma (ccRCC) is essential for guiding personalized treatment planning. In this study, we present a multi-modal ensemble model (MMEM) that inte...

Enhancing Adaptive Radiotherapy Segmentation with a 3D Unet Framework and Prior Fraction Information

Authors: Jennifer L. Dolan, Chengyin Li, Parag Parikh, Doris N. Rusu, Kundan S Thind

Affiliation: Henry Ford Health, Cedars-Sinai Medical Center

Abstract Preview: Purpose: The time and resource demands of online Adaptive Radiation Therapy (ART) can limit its widespread clinical adoption and potentially impact patient throughput. To address this, we developed a ...

Establishing a Protocol for Quality Assessment of Ultrasound Shear Wave Elastography (SWE) and Application to a Musculoskeletal (MSK) Task

Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...

Estimation of Brain Tumor’s Intra-Fraction Movement during Radiosurgery Using Fiducial Markers on the Skin Surface – a Simulation Study

Authors: Damien C. Mathew, Brandon Hai Nguyen, Satwik Pani, Yoichi Watanabe

Affiliation: Minnespolis Radiation Oncology, Department of Radiation Oncology, University of Minnesota Medical School, Washington University

Abstract Preview: Purpose: To formulate a computational algorithm to quantify the tumor movement from the motion data of landmarks on the brain surface. To estimate the magnitude of tumor movement when the head makes a...

Evaluating PET-Based Metrics to Identify Patients with Liver Metastases for Biology-Guided Radiotherapy

Authors: Girish Bal, Ke Colin Huang, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue

Affiliation: Purdue University, RefleXion Medical, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) uses real-time positron emission tomography (PET) signals to precisely direct radiotherapy beamlets. The success of BgRT planning and delivery relies on PET...

Evaluating Target Isocenter Accuracy in Off-Isocenter Treatments Using an Extended Winston-Lutz Test

Authors: Maria de la Luz De Ornelas, Yunze Yang

Affiliation: University of Miami

Abstract Preview: Purpose:
An extended Winston-Lutz test (EWL), also known as off-axis Winston-Lutz, was performed to assess the linear accelerator’s (linac) deviations at isocenter and five off-iso targets. The imp...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluating the Performance and Limitations of an Automated Treatment Planning Tool for Intact Breast Radiotherapy across Diverse Patient Populations

Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling

Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX

Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...

Evaluation of MR Proton Density Fat Fraction (PDFF) for Bone Marrow Protection in RT

Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang

Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital

Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...

Evaluation of MRI Distortion across a Multi-Site Health System and the Importance of MRI Distortion QA in Stereotactic Radiosurgery (SRS)

Authors: Emel Calugaru, Jenghwa Chang, Sean T Grace, Nicholas Harvey, Jessica Jung, Ching-Ling Teng

Affiliation: Northwell, Hofstra University, Hofstra University Medical Physics Program

Abstract Preview: Purpose: To evaluate the consistency of MRI distortion corrections across Northwell Health system and evaluate the necessity and importance of distortion QA for MRIs used for stereotactic radiosurgery...

Evaluation of a Commercial Metal Artifact Reduction Algorithm for IGRT in Patients with Hip Prostheses

Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson

Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison

Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...

Extending Chronorepair: A Computational Model of the Effects of Radiotherapy in Cells

Authors: Alejandro Bertolet, Jose Antonio Lopez-Valverde, Victor V. Onecha, Daniel Puerta

Affiliation: Dana Farber Cancer Institute/Brigham and Women's Hospital, Departamento de FĂ­sica AtĂłmica, Molecular y Nuclear, Universidad de Granada, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Besides its superior dose conformity, proton therapy induces greater damage to tissue than conventional radiotherapies. This increased damage is usually quantified through the concept of rela...

Feasibility Study of Group Sparse-Based Beam Angle Optimization for Multi-Field Carbon Ion Radiotherapy

Authors: Min Cheol Han, Hojin Kim, Jin Sung Kim, Hyejin Lee, Sac Lee, Yongdo Yun

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine

Abstract Preview: Purpose: Carbon ion radiotherapy (CIRT) is characterized by high relative biological effectiveness (RBE), which must be integrated into the treatment planning process. This study aims to develop a nov...

Film-Based Method for Accurate Radiation Isocenter Determination in Linear Accelerators Using 3D Starshot

Authors: Robert A. Corns, Mohammad Kanber

Affiliation: East Carolina University, East Carolina University Brody School of Medicine

Abstract Preview: Purpose:
Accurate determination of the radiation isocenter is crucial for precise radiotherapy treatments, directly impacting patient safety and treatment quality. This study presents a computation...

Financial Viability Analysis of on-Table Simulation Enabled Halcyon Using Time Driven Activity-Based Costing

Authors: Xinyuan Chen, Geoffrey D. Hugo, Alex T. Price, Pamela Samson, Tianyu Zhao

Affiliation: University Hospitals Seidman Cancer Center, University of South Florida, Washington University School of Medicine, WashU Medicine

Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...

Financial Viability of on-Table Simulation Enabled Halcyon System Using Time Driven Activity-Based Costing Analysis.

Authors: Xinyuan Chen

Affiliation: Washington University School of Medicine

Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...

Finding the Best Match of 4D-CT Phases to Delineate Volumes for Bgrt

Authors: Resat Aydin, Joseph Barbiere, Brett Lewis, Roland Teboh

Affiliation: HUMC, Hackensack University Medical Center

Abstract Preview: Purpose:
Accurately compensating for respiratory-induced tumor motion is critical in BgRT, where precise delineation of volumes ensures effective dose delivery. We propose an integrated approach th...

Foundation Models with Balanced Data Sampling Enhance Auto-Segmentation for Cardiac Substructures

Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...

Four-Dimensional Computed Tomography Based on 16cm-Long Detectors Vs 4cm-Long Detectors: Dose Validation

Authors: Qianyi Xu, Inhwan Yeo

Affiliation: INOVA Schar Cancer Institute, Thomas Jefferson University

Abstract Preview: Purpose:
Four-dimensional computed tomography(4DCT) is prone to a geometrical error when respiration changes upon patient shift. 4DCT with a longer-length detector(16cm), uninvolving the shift, has...

Geometric Alignment of MV-CBCT and Dual-Layer Kv-CBCT Projections Using Deep Learning

Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis

Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute

Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...

Getting in Focus: Review of Current Focal Spot Size Testing Methods with Flat Panel Digital Radiography Detectors

Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda

Affiliation: Yale University School of Medicine, Yale University

Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...

Glandular Dose Map in Voxelized Phantoms across Advanced Breast Imaging Modalities Obtained from Monte Carlo Simulations

Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin

Affiliation: Universidade Estadual de Campinas. Instituto de FĂ­sica Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven

Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...

Global Medical Physics Graduate Clinical Training and Development Program

Authors: Eric Addison, Stephen M. Avery, Alhassan Mohammed Baidoo, Lyna Dinh, Megan Doherty, Andrew Friberg, Sonya Gwak, Francis Hasford, Stephen Inkoom, Shannon E. O'Reilly, Ayoola Okuribido, Edem Sosu, Samuel Nii Adu Tagoe

Affiliation: University of Wisconsin, Komfo Anokye Teaching Hospital, Ghana Atomic Energy Commission, Korle Bu Teaching Hospital, University of Pennsylvania, University of Ghana, Sweden Ghana Medical Centre

Abstract Preview: Purpose: This first-of-its-kind Global Medical Physics Training and Development Program (GMPTDP) seeks to serve as an opportunity for graduate students to enhance their clinical training with a global...

Hands-on AI Education for Radiology Residents

Authors: Wilfred R Furtado, Gary Y. Ge, James Lee, Jie Zhang

Affiliation: University of Kentucky

Abstract Preview: Purpose: Despite advancements in Artificial Intelligence (AI) and its growing role in clinical practices like radiology, formal AI education remains limited in medical training. This gap contributes t...

HyperArcTM Automated Radiosurgery Planning Enables Accurate a Priori Isotoxic Prescription Dose Selection

Authors: Rex A. Cardan, Carlos E. Cardenas, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li, Rodney J. Sullivan, Natalie N. Viscariello, Christopher Willey

Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: vBrain radiosurgery toxicity-rate is estimated via clinically-relevant isodose volume (IDV) thresholds according to HyTEC (e.g., V12Gy≀10cc). HyperArcTM (HA) automated planning allows accurat...

Impact of Arc Number Variation on VMAT Lattice Radiotherapy Plans

Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu

Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan

Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...

Impact of Feraheme on Imaging and Thermal Dynamics during MR-Guided Focused Ultrasound: Phantom Study

Authors: Jaydev K. Dave, Krzysztof R Gorny, Chunming Gu, Nicholas J. Hangiandreou, Gina K. Hesley, Myung-Ho In, Zaiyang Long, Aiming Lu, Christin A. TiegsHeiden

Affiliation: Mayo Clinic

Abstract Preview: Purpose:
MR-guided focused ultrasound (MRgFUS) enables precise tumor ablation with real-time MR-thermometry guidance. Our practice is exploring the potential use of Feraheme (Ferumoxytol), a superp...

Impact of Tracking By Jaws or Mlc on Treatment Accuracy in Synchrony Modality for Tomohelical Technique

Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Anthony Nagy, Stéphane Nevesny, Nicolas Joel Lionel Perichon

Affiliation: Clinique De Genolier

Abstract Preview: Purpose: Real-time tracking is implemented on Radixact by detecting the target position with 2D-kV image either directly (for lung tumors), or indirectly (using fiducials as surrogates), and by adapti...

Impact of a Dedicated Working Group on Standardization of CT-Guided Adaptive Radiation Therapy

Authors: Anthony J. Doemer, Aharon Feldman, Ian Gallagher, Yimei Huang, Brett M. Miller, Benjamin Movsas, Kundan S Thind

Affiliation: Henry Ford Health

Abstract Preview: Purpose: CT-guided adaptive radiation therapy (CTgART) is a technical, resource intensive, procedure that involves many different radiation oncology team members. To ensure consistent, high-quality CT...

In-Silico Clinical Trials Enabled By Digital Twin Approach Can Accurately and Prospectively Predict Outcomes of Clinical Trials Combining Radiation and Systemic Therapy

Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital

Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...

In-Vivo Image Quality of Head/Neck and CNS with an Advanced C-Arm Linac CBCT Solution

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...

Inconsistencies in Methods for CMS Size-Adjusted Dose Measure

Authors: Alexander Alsalihi, Gary Y. Ge, Charles Mike Weaver, Jie Zhang

Affiliation: University of Kentucky

Abstract Preview: Purpose: The upcoming CMS regulation, titled “Excessive Radiation Dose or Inadequate Image Quality for Diagnostic Computed Tomography (CT) in Adults”, employs two measures, size-adjusted DLP (SAD) and...

Initial Three-Year Machine Performance Assessment of a Superficial Radiation Therapy Unit

Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...

Innovative Deep Learning Network for Overall Survival Prediction for NSCLC: Outperforming Pre-Trained Models VGG16 and ResNet50

Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder

Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida

Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...

Inter-Fraction Monitoring of Brain Metastases Resection Cavities during Fractionated Stereotactic Radiosurgery on the 0.35 T MRI-Linac

Authors: Eyub Y. Akdemir, Gregory A Azzam, Rupesh Kotecha, Gregory J. Kubicek, Natalia Lutsik, Eric Mellon, Siamak P. Nejad-Davarani, Parag Parikh, Karen C. Snyder

Affiliation: Miami Cancer Institute, Baptist Health South Florida, Department of Radiation Oncology, University of Miami, Henry Ford Health

Abstract Preview: Purpose: Resection cavity volumes shrink gradually over time after surgical resection of brain metastases. Fractionated stereotactic radiosurgery (fSRS) is often delivered to the cavity to prevent rec...

Inter-System and Inter-Layer Dlg Variations in Halcyon/Ethos Mlcs: Implications for Dosimetric Matching and User-Adjustable TPS Models

Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler

Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC

Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...

Interpretable Deep Learning Predicts Metastasis-Free Survival (MFS) from Conventional Imaging for Oligometastatic Castration-Sensitive Prostate Cancer (omCSPC) Using Multi-Modality PSMA PET and CT Imaging.

Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran

Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine

Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...

Investigating Factors Impacting the Consistency of Signal-to-Noise Ratio in Mammographic Automatic Exposure Control

Authors: James Ward, Anzi Zhao

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: This study investigates the impact of tissue-equivalent attenuator materials, the region of interest (ROI) size, and the orientation of the attenuator positioning on the measured signal-to-no...

Investigation of Prompt Gamma Imaging Using a Three Axis Rotating Compton Camera

Authors: Molokotima Kekana, Dennis S. Mackin, Stephen W. Peterson, Jerimy C. Polf

Affiliation: Department of Physics, University of Cape Town, M3D, Inc, The University of Texas MD Anderson Cancer Center, Houston

Abstract Preview: Purpose: To study the imaging characteristics of a prototype prompt gamma (PG) imaging system consisting of multiple rotating Compton cameras (CC).

Methods: The prototype CC imaging system is c...

Knowledge-Based Three-Dimensional Dose Prediction for High Dose Rate Prostate Brachytherapy

Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi

Affiliation: UC San Diego, Virginia Commonwealth University

Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

Large Scale Deployment of a Tailored and Hybrid Educational Strategy for Wartime Capacity Building: Aapm/HUG/Uamp Initiative to Transition Ukraine from Co-60 to IMRT through a Comprehensive Medical Physics Training Program

Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi

Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital

Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...

Learning from Failures – Case Studies into Failing Patient Specific Quality Assurance Plans

Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh

Affiliation: Tufts Medical Center

Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...

Lu-177 Recovery Coefficients Using Tc-99m Surrogate Method: Intra- & Inter-Scanner Comparison

Authors: Ben Piacitelli, Celeste Winters

Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University

Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...

Medical Physics Nextgen: Inspiring Undergraduate Students to Pursue Medical Physics in the Eastern Mediterranean Region By Focusing on Local Needs

Authors: Wamied T. Abdel-Rahman, Iqbal AlAmri, Lma Alahmare, Ghada Aldosary, Marwa Alghamdi, Lujain Aljadou, Yarah Alkhulaif, Abdullah A. Alshreef, Ohoud Alsubaie, Hoton Alsufyani

Affiliation: Loma Linda University Medical Center, Princess Nourah Bint Abdulrahman University, King Fahad Specialist Hospital, KAMC- Ministry of National Guard Health Affairs, SQCCCRC, KASCH- Ministry of National Guard Health Affairs

Abstract Preview: Purpose: The shortage of qualified medical physicists in many developing countries is due to multiple factors such as lack of awareness or access to graduate and residency training programs. An outrea...

Micro-Ultrasound Guided Focal Prostate Radiotherapy: Development and Testing of a Novel Device.

Authors: Kevin Barker, David Jeffrey Contella, Chandima Edirisinghe, Aaron Fenster, Douglas A Hoover, Elizabeth Huynh

Affiliation: Robarts Research Institute, University of Western Ontario, London Health Sciences Center, Department of Radiation Oncology, London Health Sciences Centre

Abstract Preview: Purpose: We aim to develop a system that integrates micro-ultrasound into focal prostate cancer radiotherapy. This requires developing a mechatronic stepper capable of performing motorized rotation of...

Mitigating Data-Driven Uncertainty in Machine Learning-Based Radiotherapy Outcome Prediction

Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu

Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich

Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...

Modulation of the Tumor Microenvironment By Radiation Therapy to Enhance Immune Activity in Glioblastoma

Authors: MacKenzie Rachelle Coon, Justin Geise, Judith Noemi Rivera, Matthew L. Scarpelli, Jessica Leigh Veenstra, Chandler Zaugg

Affiliation: Purdue University, Indiana University

Abstract Preview: Purpose: Glioblastoma (GBM) is among the most aggressive and treatment-resistant cancers due to its immunosuppressive tumor microenvironment. Immunotherapy holds promise for GBM treatment, but its eff...

Monte Carlo Modeling of an Experimental X-Ray Fluorescence Computed Tomography (XFCT) System with a Pixelated CdTe Detector

Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...

Multi-Center Diffusion-Weighted MRI Validation for 0.35T MR-Linac: A Repeatability and Reproducibility Study

Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami

Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...

Multi-Modality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma

Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie

Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine

Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...

Multi-Organ Segmentation of Pelvic Cone-Beam Computed Tomography (CBCT) with Transformer Models to Enhance Adaptive Radiotherapy for Prostate Cancer

Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...

Multi-Scale, Multi-Task Framework with Jacobian Descent for Multi-Plan Dose Prediction in Sequential Boost Radiotherapy

Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas

Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...

Multi-Variat, Multi-Model, and Multi-Patient: From Pure Feasibility to Generalizability in Machine Learning Outcome Prediction Model-Based Treatment Plan Optimization

Authors: Martin Frank, Oliver JĂ€kel, Niklas Wahl

Affiliation: Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Karlsruhe Institute of Technology (KIT)

Abstract Preview: Purpose: Machine learning (ML) models on normal tissue complication and tumor control probability ((N)TCP) exploiting e.g. dosiomic and radiomic features are playing an increasingly important role in ...

NA-Unetr: A Neighborhood Attention Transformer Network for Enhanced 3D Segmentation of the Left Anterior Descending Artery

Authors: Hassan Bagher-Ebadian, Ahmed I Ghanem, Joshua P. Kim, Chengyin Li, Rafi Ibn Sultan, Kundan S Thind, Dongxiao Zhu

Affiliation: Wayne State University, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health

Abstract Preview: Purpose: Accurate segmentation of the Left Anterior Descending (LAD) artery in free-breathing 3D treatment planning CT is crucial for radiotherapy but remains challenging due to its small size, comple...

NTCP Modeling and Dose-Volume Correlations for Rectal Symptoms Following Prostate Cyberknife SBRT.

Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy

Affiliation: University of South Florida, University of North Carolina

Abstract Preview: Purpose: To correlate four rectal symptoms with the dose to rectum in patients, who received SBRT with Cyberknife for prostate cancer. Also, to fit those dosimetric and outcome data by using a normal ...

Next Generation Nanoparticles for Fractionated MRI-Guided Radiation Therapy

Authors: Stephanie Bennett, Ross I. Berbeco, Guillaume Bort, Needa Brown, Lena Carmes, Sandrine Dufort, Michael John Lavelle, Geraldine Le Duc, Francois Lux, Toby Morris, Zeinaf Muradova, Andrea Protti, Olivier Tillement

Affiliation: University de Lyon, NH TherAGuIX, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Department of Radiation Oncology, Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, NH TherAguix, Universite de Lyon, Brigham and Women's Hospital, Dana-Farber Cancer Institute

Abstract Preview: Purpose: AGuIX is a theranostic Gd-based nanoparticle currently under phase-2 clinical testing where patients receive 2-3 doses at 1-week intervals prior to imaging and irradiation. AGuIX-Bi is a new ...

Online Active Learning Strategies for Global Medical Physics Education: A Scoping Review

Authors: Mary Gronberg, Kelly Kisling, Ana Maria Marques da Silva

Affiliation: University of California, San Diego, The University of Texas Southwestern Medical Center, Pontifical Catholic University of Rio Grande do Sul

Abstract Preview: Purpose: To evaluate the current status of online teaching in medical physics and identify effective active learning strategies for global medical physics education.
Methods: A scoping review was c...

Optimization of the U-Net Model for the Radiation Dose Prediction in Lung Cancer RT Plans and Its Uncertainty Quantification

Authors: Ibtisam Almajnooni, Victor Cobilean, Milos Manic, Harindra Sandun Mavikumbure, Elisabeth Weiss, Lulin Yuan

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: This study aims to optimize the 3D U-Net architecture for dose prediction in lung cancer radiation therapy (RT) plans, particularly in scenarios with limited clinical data, as well as to quan...

Patient Education through Virtual Reality: Project Development

Authors: Alison Amos, Alan H. Baydush, Shawna Buchanan, Nicole Carone, Sarah Cummings, Corey Henderson, Christy Hickerson, Gretchen Kessler, Sydney Lash, Kelli Reardon, Michelle Rokni, Sarah B. Wisnoskie, Ashlyn Zebrowski

Affiliation: UNC-Chapel Hill, UNC Chapel HIll, Novant Health

Abstract Preview: Purpose: As Medical Physics 3.0 (MP3.0) progresses, many clinics are integrating consultations with physicists to educate cancer patients, reduce stress, and enhance the patient experience. However, d...

Physician-Centered Decision-Making Tool for Individualized Outcome-Based Treatment Planning

Authors: Soren Bentzen, Arezoo Modiri, Zaker Rana, Amit Sawant, Lena Specht, Ivan Vogelius

Affiliation: University of Maryland, University of Maryland in Baltimore, Dept. Of Oncology Copenhagen University Hospital – Rigshospitalet, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: There is wide inter-physician radiotherapy planning variability for lymphomas and no systematic way to individualize a plan with respect to patient-specific outcome risks. In response to this...

Pilot Clinical Implementation of Auto-Planning Using Multicriteria Optimization for Pelvis Radiotherapy

Authors: Shifeng Chen, Erica Fisler, Arun Gopal, Mariana Guerrero, Jason Hendershot, Kai Huang, Eric Kusmaul, Adam Schrum, Megan Steinberg, Kai Wang

Affiliation: University of Maryland School of Medicine, Department Radiation Oncology, Kaufman Cancer Center, Upper Chesapeake Medical Center, University of Maryland Medical System Central Maryland Radiation Oncology, Department of Radiation Oncology, University of Maryland Medical Center, Baltimore Washington Medical Center Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose:
Our goal is to develop and clinically deploy an automated planning tool using multicriteria optimization (MCO) for VMAT in prostate only, whole pelvis radiotherapy treatments.
Methods:<...

Predicting Pathological Complete Response to Neoadjuvant Chemotherapy for Breast Cancer at Early Time Points Using a Two-Stage Dual-Task Deep Learning Strategy

Authors: Bowen Jing, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Medical images acquired at multiple time points during neoadjuvant chemotherapy allow physicians to assess patients’ responses and personalize treatment plans accordingly. Studies from the I-...

Predicting Prostate Cancer Recurrence Using an Atlas-Based Tumor Control Probability Model

Authors: Jeremy T. Booth, Martin Andrew Ebert, Robert Finnegan, Annette Haworth, George Hruby, Burhan Javed, Kazi Ridita Mahtaba, Leyla Moghaddasi, Yutong Zhao

Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, The University of Sydney, The University of Western Australia, Genesis Care, Rockhampton Hospital

Abstract Preview: Purpose:
To evaluate the efficacy of an atlas-based tumor control probability (TCP) model in predicting prostate cancer (PCa) recurrence by retrospectively integrating patient-specific primary radi...

Prediction of Head and Neck Cancer Using Artificial Neural Network through Basic Health Data

Authors: Abdullah Hidayat, Wazir Muhammad

Affiliation: Florida Atlantic University

Abstract Preview: Purpose: This study aims to predict Head and Neck cancer using an artificial neural network (ANN) through readily available basic health data. The goal is to uncover hidden patterns and predictors in ...

Prediction of Metastasis-Free Survival in Patients with Prostate Adenocarcinoma Using Primary Tumor and Lymph Node Radiomics from Pre-Treatment PSMA PET/CT Scans.

Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran

Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...

Prospective Organ-Level Dose Estimation in CT Imaging Using Scout-Net: A Comparison with Established Methods

Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang

Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University

Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...

Prostate Dosimetric Comparison between Cyberknife and Radixact Modalities Using Precision and Raystation Planning Systems

Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon

Affiliation: Clinique De Genolier

Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...

Proton Therapy Treatment Planning for Thoracic Cancer: A Comparative Analysis of Single and Multi-Field Plans

Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu

Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection

Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...

QA Your QA:3 Steps to Ensure a Robust QA Review Workflow.

Authors: Shahid B. Awan, Harold Li, Aba Lippuner

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: QA review is a necessary component of QA management but is often pushed aside owing to time constraints and overreliance on vendor solutions. At our multicenter institution, we designed a 3-s...

Qualitative Assessment of Low-Dose 4D Cone-Beam CT Protocols for Daily Lung SBRT Patient Alignment

Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske

Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ

Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...

Quality Assurance of Four-Dimensional Computed Tomography (4DCT)

Authors: Teh Lin, Anna Oneil

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...

Radiopharmaceutical-Free Assessment of Tumor Vasculature Condition in Particle Therapy By Means of Range-Verification PET: A Feasibility Rat Study

Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya

Affiliation: National Institutes for Quantum Science and Technology

Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...

Real-Time 3D Visualization of Electric Field with Electroacoustic Tomography

Authors: Jadon O Buller, Yankun Lang, Liangzhong Xiang, Andrea Paulina Yanez

Affiliation: University of Maryland School of Medicine, University of California, Irvine

Abstract Preview: Purpose: With the widespread adoption of electroporation, there is growing interest in deep-tissue electric field monitoring. Electroporation therapy ablates target regions by generating electric fiel...

Real-Time Observation of Radiation-Induced DNA Damage for Radiopharmaceuticals

Authors: Denis Bergeron, Brittany Broder, Sean Jollota, Ahtesham Ullah Khan, Michael Lamontagne, Joseph W. Robertson

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, National Institute of Standards and Technology

Abstract Preview: Purpose: We present new methodology for real-time measurement of radiation-induced DNA damage caused by radiopharmaceuticals. Building on previous efforts to measure DNA fragmentation with nanopore se...

Redefining the Down-Sampling Scheme of U-Net for Precision Biomedical Image Segmentation

Authors: Yizheng Chen, Md Tauhidul Islam, Mingjie Li, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
Biomedical image segmentation (BIS) is a cornerstone of medical physics, enabling accurate delineation of anatomical structures and abnormalities, which is critical for diagnosis, treatmen...

Respiratory Monitoring in Human Subjects Using a Low-Cost Optical Imaging System Prototype

Authors: Marian Axente, Mandeep Kaur

Affiliation: Emory University

Abstract Preview: Purpose: To validate a low-cost optical imaging system for respiratory monitoring by comparing its accuracy and feasibility against the clinical gold standard in human subjects.
Methods: Following ...

Robust Estimation of Cell Microstructure Parameters Via Diffusion MRI Cytometry

Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cell microstructure information is critical for radiotherapy response assessment. Diffusion MRI (dMRI) offers great potential in deriving cell parameters. Yet parameters estimated in existing...

Scan Efficiency and Imaging Dose Analysis of Next-Generation Nonstop Gated CBCT for Respiratory Gating Lung Radiotherapy

Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yusuf Emre Erdi, Yabo Fu, Yiming Gao, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Tianfang Li, Xiang Li, Seng Boh Gary Lim, Jean M. Moran, Mitchell Yu, Hao Zhang

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Gated CBCT (gCBCT) is commonly employed for respiratory gating lung cancer patients to ensure precise patient setup. However, the scan is time-consuming on C-arm linear accelerators (LINAC) d...

Simultaneous Synthesis of Lung Perfusion and Ventilation Images from CT Using a Dual-Decoder Residual Attention Network for Lung Disease Diagnosis

Authors: Li-Sheng Geng, David Huang, Haoze Li, Xi Liu, Meng Wang, Tianyu Xiong, Ruijie Yang, Weifang Zhang, Meixin Zhao

Affiliation: School of Physics, Beihang University, Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, Peking University Third Hospital, Department of Nuclear Medicine, Peking University Third Hospital, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aimed to develop a deep learning-based framework for simultaneously generating lung perfusion and ventilation images from three-dimensional computed tomography (3D CT) images.
M...

Spectral CT Assessment of 3D Printing Techniques for Improving the Uniformity and Reproducibility of Models Applied in Medical Imaging

Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon

Affiliation: University of Florida College of Medicine, University of Florida

Abstract Preview: Purpose: Filament deposition modeling (FDM) 3D printers may utilize proprietary calibration methods inadequate for medical imaging. Proper techniques are necessary to achieve imaging uniformity standa...

Spot Scanning Gantry-Based Gaze-Gated Ocular Proton Treatment Planning at Mayo Clinic Rochester

Authors: Amanda J. Deisher, Susannah V. Hickling, Shima Ito, Jon J. Kruse

Affiliation: CancerCare Manitoba, Mayo Clinic

Abstract Preview: Purpose:
To date, 11 ocular patients were treated with spot scanning gantry-based gaze-gated ocular proton program at Mayo Clinic, Rochester MN since 2023. Treatments are done in the half-arc gantr...

Streamlined Proton Registry Interface for Patient Subtyping and Assessment Integration

Authors: Curtiland Deville, Rachel B. Ger, Elaina Hales, Heng Li, Todd R. McNutt

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Lack of specialized coding knowledge limits the use of data from large SQL repositories. We aimed to develop intuitive user interfaces for a registry that allows users to visualize the relati...

Streamlining Quad-Shot Radiotherapy: Automated Workflow Enables Same-Day Treatment for Palliative Lung Cancer

Authors: Laura I. Cervino, Sharif Elguindi, Yu-Chi Hu, Licheng Kuo, Xiaoning Liu, Jennifer Ma, Pengpeng Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Radiation Oncology, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
Quad-shot radiotherapy (QSRT) is an emerging paradigm in palliative cancer treatment. This study aimed to streamline the QSRT workflow using automation to improve efficiency while maintain...

Synthesizing High-Quality Hepatic Vascular Tree Segmentation Datasets to Improve Segmentation Model Performance

Authors: Trevor McKeown, Deshan Yang, Zhendong Zhang

Affiliation: Duke University, Department of Radiation Oncology, Duke University

Abstract Preview: Purpose: Accurate delineation of liver blood vascular structures is crucial for planning and executing therapeutic interventions in liver-related medical procedures. However, current auto-segmentation...

Teaching an Old Dog New Tricks: Unlocking Hidden Potential in Existing Frameworks for Versatile Radiotherapy Applications

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...

The Comparison of Radiation Uses in Common Procedures Amongst Didactic Pediatric Fluoroscopic Units

Authors: Janet Ching-Mei Feng, Jimmy Huynh

Affiliation: UTHealth McGovern Medical School

Abstract Preview: Purpose: The Image Gently Alliance had provided helpful information to optimize image protocols in pediatric patients since 2007, and our assumption was that newer units could use near-to-optimal prot...

Three-Dimensional Reconstruction of Triggered Images with Dehazing Algorithm for Precise Intrafraction Motion Detection in Spine SBRT

Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University

Abstract Preview: Purpose: To precisely detect intrafraction patient motion during spine stereotactic body radiotherapy (SBRT) treatment delivery, we propose an optimized technique for three-dimensional reconstruction ...

Treatment Plan Evaluation of the Patient-Tailored Architect Applicator for Cervical Cancer Brachytherapy

Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez

Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam

Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...

Two's Company, Three's a Crowd? a Bayesian Approach to Optimizing the Number of Measurement Readings in Radiation Therapy QA

Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen

Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...

Uncertainty Analysis for Effective Dose Conversion Factors in CT

Authors: Renxin Chu, Jelena Mihailovic, Kai Yang, Lifeng Yu, Da Zhang

Affiliation: Massachusetts General Hospital, Mayo Clinic, Boston Children's Hospital, UVA Health University Hospital, University of Missouri Health Care

Abstract Preview: Purpose:
A frequently used method to estimate effective dose (ED) in CT is by multiplying the dose length product (DLP) by a conversion factor, known as k-factor. The k-factor in this method is sus...

Universal Anatomical Mapping and Patient-Specific Prior Implicit Neural Representation for MRI Super-Resolution

Authors: Jie Deng, Yunxiang Li, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Magnetic Resonance Imaging (MRI) has exceptional soft tissue contrast and an essential role in radiotherapy. The introduction of clinical MR-LINACs has enabled adaptive radiotherapy (ART) usi...

Using Machine Learning to Predict Esophagitis Risk in Lung Cancer Radiotherapy Based on Clinical and Dosimetric Factors

Authors: Ibtisam Almajnooni, Siyong Kim, Nathaniel Miller, Elisabeth Weiss, Lulin Yuan

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: Radiation-induced esophagitis (RE) is a common concern in lung cancer IMRT. Recent studies have indicated that the risk of radiation side effects varies greatly with patients’ baseline clinic...

Using Multi-Peak Reconstructions for Dosimetry of Fast and Quantitative Lutetium-177 SPECT/CT

Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija

Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging

Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...

Weak-to-Strong Generalization for Interpretable Deep Learning-Based Histological Image Classification Guided By Hand-Crafted Features

Authors: Mark Anastasio, Zong Fan, Hua Li, Changjie Lu, Lulu Sun, Xiaowei Wang, Zhimin Wang, Michael Wu

Affiliation: University of Illinois at Urbana-Champaign, University of Illinois at Chicago, Washington University School of Medicine, University of Illinois Urbana-Champaign, Washington University in St. Louis, University Laboratory High School

Abstract Preview: Purpose: Histological whole slide images (WSIs) are vital in clinical diagnosis. Although deep learning (DL) methods have achieved great success in this task, they often lack interpretability. Traditi...

Whole Heart Sparing Ethos Adaptive Radiotherapy for Lung Cancer

Authors: Ibrahim Aref, David Bergman, Justine M. Cunningham, Payton Dolan, Aharon Feldman, Yimei Huang, Joshua P. Kim, Brett M. Miller, Emily Moats, Benjamin Movsas, Kundan S Thind

Affiliation: Henry Ford Health

Abstract Preview: Purpose: Cardiac radiation dose is directly associated with adverse cardiac events which are predictive of mortality in lung cancer patients. In fractionated lung radiotherapy, studies have shown a hi...