Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2Dâ3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Raneem Atta, Alejandro Bertolet, Mislav BobiÄ, Wesley E. Bolch, Robert Joseph Dawson, Carlos Huesa-Berral, Harald Paganetti, Eric Wehrenberg-Klee
Affiliation: Massachusetts General Hospital, University of Florida, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital and Harvard Medical School, Department of Radiology, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Representations of intra-organ vasculature have a variety of uses in the field of computational dosimetry but generally rely on models derived from population-averaged reference individuals. ...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Stephen Shang
Affiliation: South Florida Proton Therapy Institute, SFPRF
Abstract Preview: Purpose: Proton pencil beam scanning therapy is particularly sensitive to field translational shifts and beam range variations, which can degradation of dose distribution and compromise the treatment....
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Mohamed Bahaaeldin Mohamed Afifi, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Fox Chase Cancer Center, Radiological Sciences and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University.
Abstract Preview: Purpose: Reirradiation of recurrent cancer or a newly developed lesion in a proximal location poses a challenge for radiation treatments. This is occasionally encountered in many modern clinics and ef...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou Peopleâs Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleĘźs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...
Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...
Authors: Matthew J Ferris, Jason K Molitoris
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose: Anatomy changes often happen in head-and-neck (HN) patients treated with proton radiation therapy. These changes can result in deteriorations of target dose coverage and increased dose to org...
Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins
Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC
Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patientsâ ...
Authors: Yingxuan Chen, Jun Li, Alexis N. Webb
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Cone-beam computed-tomography (CBCT) is widely used for image-guided therapy. Cumulative dose from repeated CBCT might be a concern. This study aims to measure and compare the CBCT dose for c...
Authors: Martha J. Malin, Matthew Schelin
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.
Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy
Affiliation: University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...
Authors: Mark E Artz, Julie Bradley, Hardev Singh Grewal, Perry B. Johnson, Christina Klassen, Raymond Mailhot Vega, Nancy Mendenhall, Jiyeon Park, Emma V. Viviers, Yawei Zhang
Affiliation: UF Health Proton Therapy Institute, University of Florida
Abstract Preview: Purpose: Verification CTs (VFCT) are used in radiotherapy to assess patient dose during treatment. However, they are time-consuming and contribute additional radiation exposure to the patient. This st...
Authors: Mahmoud H Abdelgawad, Shahabeddin mostafanazhad Aslmarand, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Teh Lin, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Physics department, Faculty of science, Al-Azhar University, Fox Chase Cancer Center
Abstract Preview: Purpose: Many modern radiotherapy clinics are moving to online adaptive radiotherapy. A recent upgrade of the CBCT-based adaptive radiotherapy system introduced ultra-high-speed image acquisition. Thi...
Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...
Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...
Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...
Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) doses shall be limited for pediatric patients in clinical settings. Device called Filtimator (filter+collimator) was custom designed to reduce setup CB...
Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patientâs nose relative to two stationary reflectors on th...
Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng
Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Lei Ren, Jie Zhang
Affiliation: University of Maryland School of Medicine
Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...
Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy
Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics
Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...
Authors: Yijian Cao, Jenghwa Chang, Lyu Huang
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systemsâVarianâs TrueBeam (C-arm) and Halcyon (O-ring)âfor prostate Stereotactic Body Ra...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.
Methods: Dose calculations in water phan...
Authors: Michelle Alonso-Basanta, Joshua Bryer, Lei Dong, Barbara Garcia, Elissa Khoudary, Brandon M. Koger, Taoran Li, Michael Salerno, Karen Tang, Boon-Keng Kevin Teo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: The Varian HyperSight imaging solution features a workflow for planning on CBCT images (CBCTp). This study evaluates the feasibility of CBCTp images in the setting of an offline adaptive plan...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To compute effective doses associated with imaging of the extremities with a HiRise (CurveBeam AI, Hatfield, PA) cone-beam CBCT scanner specifically designed for weight-bearing imaging of the...
Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis
Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Xinyuan Chen, Geoffrey D. Hugo, Alex T. Price, Pamela Samson, Tianyu Zhao
Affiliation: University Hospitals Seidman Cancer Center, University of South Florida, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Xinyuan Chen
Affiliation: Washington University School of Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero LÜnnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität Mßnchen (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) Mßnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital
Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: James M. Lamb, Dishane Chand Luximon, Jack Neylon, Rachel Petragallo, Moritz Ritter, Timothy Ritter
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, ETH Zurich, VCU Health System, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: Anomalies in cone beam computed tomography (CBCT) radiotherapy image guidance can signal treatment deviations. Repetitive review of setup image registrations by humans is inefficient, prone t...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...
Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam
Affiliation: University of Michigan
Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: Wesley A. Belcher, Robert A. Corns, Jae Won Jung, Matthew S Peach, Swarup Sharma
Affiliation: The University of North Carolina at Chapel Hill, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: GammaTiles are a novel intracranial brachytherapy approach designed to directly deliver radiation therapy to residual or recurrent brain tumors following resection. Despite their promising th...
Authors: Liu Hong, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: During treatment delivery on TrueBeam platform 2.7, Triggered Imaging (TI) enables kV images acquisition at regular intervals and Auto Beam Hold (ABH) provides beam pausing if the target is m...
Authors: Hania A. Al-Hallaq, Duncan Henry Bohannon, Chih-Wei Chang, Anees H. Dhabaan, Vishal Dhere, H Scott McGinnis, Pretesh Patel, Sagar Patel, Keyur Shah, Xiaofeng Yang, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Two-fraction proton SABR is an attractive alternative to brachytherapy for localized prostate cancer. However, potential interfractional anatomical changes necessitate online adaptation, espe...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patientsâ setups. MAHR complements current image-guidance...
Authors: Gregory J Bootsma, Tunok Mondol
Affiliation: University Health Network, Princess Margaret Cancer Center
Abstract Preview: Purpose:
To evaluate the impact of prototype fluence field modulation (FFM) cone-beam CT (CBCT) on dose reduction and image quality using Monte Carlo simulations. This study particularly looks at t...
Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...
Authors: Jia Wang, Vani Yadav
Affiliation: Stanford University
Abstract Preview: Purpose: To evaluate the radiation dose and imaging quality of two novel CBCT X-Ray imaging systems used in spine surgeries.
Methods: CBCT scan of ACR CT and CTDI phantoms was performed to acquire ...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Chih-Wei Chang, Junbo Peng, Richard L.J. Qiu, Justin Roper, Xiangyang Tang, Tonghe Wang, Huiqiao Xie, Xiaofeng Yang, David Yu
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Emory Univ, Emory University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Limited-angle dual-energy (DE) cone-beam CT (CBCT) is considered a promising solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, ...
Authors: Curtiland Deville, Rachel B. Ger, Heng Li, Todd R. McNutt
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients receive quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and determine adaptive therapy needs as proton treatments are highly sensitiv...
Authors: Issra Rashed, Jennie Wilder, Jingeng Zhu
Affiliation: Rush Riverside Cancer Institute, Advanced Oncology Solutions (AOS) Varian, a Siemens Healthineers company
Abstract Preview: Purpose: Develop a method to plan and deliver homogeneous dose to Craniospinal(CS) irradiation on Linear Accelerator.
Methods: Three treatment planning volumes (PTV) are created in sequence from su...
Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego
Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patientsâ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Francis A Asamoah, David D. Campos, Jordan A Holmes, Ke Colin Huang, Omar Ishaq, Sook Kien Ng, Arpan Prabhu, Edwin Quashie, Yong Yue
Affiliation: Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Evaluate a novel rectal spacer workflow with spacer injection during brachytherapy to streamline logistics, reduce hospital visits and costs, and compare the benefits of SpaceOAR Vue and Barr...
Authors: Geoffrey D. Hugo, Eric Laugeman, Thomas R. Mazur, Pamela Samson, Kim A. Selting, Zhehao Zhang
Affiliation: University of Illinois, Washington University in St. Louis School of Medicine, WashU Medicine
Abstract Preview: Purpose: To investigate the robustness of a deep learning (DL)-based 4D-CBCT motion-compensated (MoCo) reconstruction method to out-of-distribution data.
Methods: Our developed 4D-CBCT reconstructi...
Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yusuf Emre Erdi, Yabo Fu, Yiming Gao, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Tianfang Li, Xiang Li, Seng Boh Gary Lim, Jean M. Moran, Mitchell Yu, Hao Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Gated CBCT (gCBCT) is commonly employed for respiratory gating lung cancer patients to ensure precise patient setup. However, the scan is time-consuming on C-arm linear accelerators (LINAC) d...
Authors: Michael Cummings, Olga M. Dona Lemus, Hana Mekdash, Tyler Moran, Alexander R Podgorsak, Sean M. Tanny, Matthew J. Webster, Lexiang Yang, Dandan Zheng, Yuwei Zhou, Xiaofeng Zhu
Affiliation: Department of Radiation Oncology, University of Rochester, University of Miami, Inova Schar Cancer Institute, University of Rochester
Abstract Preview: Purpose: oART is revolutionizing radiotherapy by allowing treatment plans to be adjusted based on daily imaging, improving targeting precision and potentially enhancing patient outcomes. However, its ...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Joseph A. Miccio, Nicholas J. Potter, Zain Siddiqui
Affiliation: Penn State Health Milton S. Hershey Medical Center
Abstract Preview: Purpose: Fiducial markers are the gold standard for prostate alignment during CT-based image-guided radiotherapy (IGRT). Radiopaque hydrogel rectal spacers reduce rectal toxicity by displacing the rec...
Authors: Matthew C Abramowitz, Alan Dal Pra, Rodrigo Delgadillo, Nesrin Dogan, John C. Ford, Kyle R. Padgett, Levent Sensoy, Benjamin Spieler, Matthew T. Studenski, Jace Allen Walker
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami School of Medicine
Abstract Preview: Purpose:
Toxicities that affect a patientâs quality-of-life due to prostate cancer (pCa) radiation therapy (RT) are receiving more attention as RT has become increasingly successful in treating pCA...
Authors: Steve B. Jiang, Ruiqi Li, Hua-Chieh Shao, Kenneth Westover, You Zhang, Tingliang Zhuang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Respiratory motion is a long-standing challenge for lung SBRT, particularly for centrally-located lung tumors where increased toxicity demands more precise motion management during treatme...