Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong
Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian
Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithmsâ (Radfo...
Authors: Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The recently introduced CMS regulation on CT dose and image quality mandates the use of global noise as the metric for image quality assessment. The regulation cites two methods for calculati...
Authors: Jamie s Baker, Sam Beddar, Mahsa Dehghanpour, Ariel MT Hoang, Emma Holliday, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Josie S Ruzek, Gabriel O. Sawakuchi
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, niversity of Texas MD Anderson Cancer Center School of Health Professions, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center School of Health Professions
Abstract Preview: Purpose: This study aims to evaluate the dosimetric impact on organs at risk (OAR) of small versus large spot sizes when treating pelvic cancer patients with pencil beam scanning (PBS) proton therapy....
Authors: Mubasheer Chombakkadath, Tara E. Tyson, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, University at Buffalo (SUNY)
Abstract Preview: Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART). Existing DIR phantoms either simulate tumor shape or volume changes but lack comprehensive motion simulati...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2Dâ3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Allison Dalton, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: External-beam Accelerated Partial Breast Irradiation (APBI) using stereotactic-body radiotherapy (SBRT) is increasingly adopted as an alternative to whole-breast radiation, offering targeted ...
Authors: Chloe Doen Kim, Patricia E. Lindsay, Bern Norrlinger, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Queen's University, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To propose a method to check the consistency of VMAT delivery on linear accelerator (LINAC) with a commercial three-dimensional array device. The method is insensitive to the correction facto...
Authors: Hao Gao, Yuting Lin, Nimita Shinde, Weijie Zhang
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: LATTICE, a form of spatially fractionated radiation therapy (SFRT), delivers high-dose peaks and low-dose valleys to the target volume and has been clinically used for large target volumes. H...
Authors: Grant Evans, Maxwell Arthur Kassel, Charles Shang, Stephen Shang
Affiliation: South Florida Proton Therapy Institute, SFPRF
Abstract Preview: Purpose: Proton pencil beam scanning therapy is particularly sensitive to field translational shifts and beam range variations, which can degradation of dose distribution and compromise the treatment....
Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma
Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...
Authors: Weiguo Lu, Jax Luo, Xiaoxue Qian, Hua-Chieh Shao, Guoping Xu, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Harvard Medical School
Abstract Preview: Purpose:
Semi-supervised segmentation leverages sparse annotation information to learn rich representations from combined labeled and label-less data for segmentation tasks. This study leverages th...
Authors: Paul L. Carson, Sander Dekker, Stephen Z Pinter, Megan K. Russ
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Michigan, Cablon Medical B.V., Univ of Michigan, Dept. of Radiology
Abstract Preview: Purpose:
To promote a simplified, inexpensive, but rigorous set of ultrasound QA tests and to evaluate their potential using a Randomly-placed very Hypoechoic Sphere Phantom (RHSP) in comparison to...
Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Pradeep Bhetwal, Wookjin Choi, Adam Dicker, Rupesh Ghimire, Yingcui Jia, Lauren Nkwonta, Yevgeniy Vinogradskiy, Wentao Wang, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Multi-disciplinary clinics are becoming standard of care for patients with lung cancer treated with SBRT. To improve clinical decision support in a multi-disciplinary clinic, it would be bene...
Authors: Amir Abdollahi, Oliver Jäkel, Maxmillian Knoll, Rakshana Murugan, Adithya Raman, Patrick Salome
Affiliation: UKHD & DKFZ, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), German Cancer Research Centre(DKFZ), DKFZ, MGH
Abstract Preview: Purpose:
Missing MRI sequences, due to technical issues in data handling or clinical constraints like contrast agent intolerance, limit the use of medical imaging datasets in computational analysis...
Authors: Adayabalam Balajee, Elijah Berberette, Maria Escalona, Dray Gentry, Chester R. Ramsey, Terri Ryan
Affiliation: ORAU, Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose:
Dicentric chromosomes, characterized by two centromeres on a single chromosome, are key biomarkers in biological dosimetry for quantifying ionizing radiation exposure. However, manual dete...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Curation remains a significant barrier to the use of âbig dataâ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...
Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...
Authors: James Ward, Anzi Zhao
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: This study investigates the correlation between the backlight runtime in diagnostic displays and their corresponding performance, which may aid in making informed decisions regarding the timi...
Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantitatively evaluate power-law exponent β as a potential image-based breast cancer risk factor.
Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Richard Lesieur, Olivia Magneson, David E. Solis, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the deliverability and precision of multileaf collimator (MLC) positioning in treatment plans generated by two different Treatment Planning Systems (TPS), Monaco and Pinn...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Chuangxin Chu, Haotian Huang, Tianhao Li, Jingyu Lu, Zhenyu Yang, Fang-Fang Yin, Tianyu Zeng, Chulong Zhang, Yujia Zheng
Affiliation: The Hong Kong Polytechnic University, Nanyang Technological University, Australian National University, Medical Physics Graduate Program, Duke Kunshan University, North China University of Technology, Duke Kunshan University
Abstract Preview: Purpose: Deep learning segmentation models, such as U-Net, rely on high-quality image-segmentation pairs for accurate predictions. However, the recent increasing use of generative networks for creatin...
Authors: Kyle J. Lafata, Casey Y. Lee, Xiang Li, Megan K. Russ, Zion Sheng
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
Traditional deep learning-based cell segmentation models face limitations, such as the need for extensive training data and retraining when encountering new cell types or domains. This stu...
Authors: Austin Castelo, Xinru Chen, Caroline Chung, Laurence Edward Court, Jaganathan A Parameshwaran, Zhan Xu, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
To develop a deep learning-based segmentation model to automatically delineate tumors from full-body PET/CT images.
Methods:
PET/CT image pairs of 91 patients were collected for this...
Authors: Quan Chen, Xue Feng, Chunhui Han, Gaofeng Huang, Trevor Ketcherside, Yi Lao, Yun Rose Li, An Liu, Bo Liu, Kun Qing, William T. Watkins
Affiliation: Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, City of Hope National Medical Center, Mayo Clinic Arizona, Carina Medical LLC
Abstract Preview: Purpose: New treatment platforms such as Ethos (Varian Medical Systems) allow the introduction of multi-modal imaging into adaptive radiotherapy workflow to facilitate an up-to-date view of patientsâ ...
Authors: Hongyi Jiang, Fang-Fang Yin
Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Imaging moving tissues using PET-CT can be difficult. Separating signal into phases during construction reduces signal count and increases influence of noise. Algorithms that use signal fr...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Yifei Hao, Wenxuan Li, Xiang Li, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Yaogong Zhang
Affiliation: Duke University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Diffusion-based deep-learning frameworks have been recently used in MRI resolution enhancement, or super-resolution. Multi-contrast MRI share common anatomical structures while holding comple...
Authors: Debarghya China, Junghoon Lee, Ali Uneri
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins Univ
Abstract Preview: Purpose: This study aims to develop a population-based cardio-respiratory motion model and apply it to patient-specific 3D CTA to simulate 4D CTA and 2D+t fluoroscopy sequences. The developed motion m...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos
Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen
Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...
Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania
Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...
Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu
Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust
Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...
Authors: Evan Calabrese, Hangjie Ji, Kyle J. Lafata, Casey Y. Lee, Eugene Vaios, Chunhao Wang, Lana Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University, North Carolina State University
Abstract Preview: Purpose: To develop a biologically guided deep learning (DL) model for predicting brain metastasis(BM) local control outcomes following stereotactic radiosurgery (SRS). By integrating pre-SRS MR image...
Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University
Abstract Preview: Purpose: Multi-parametric MRI (mpMRI) is widely used for deep learning (DL)-based automatic segmentation of brain tumors. While multi-contrast images concatenated as channels are typically input to ne...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Simon Brundage, Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie, Xiaofeng Zhu
Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose:
Managing departmental policies, clinical protocols, QA procedures, workflows, and troubleshooting documentation is critical in radiation oncology. A Microsoft-based wiki platform was devel...
Authors: Sophie Boisbouvier, David Cobben, Anthony L Criscuolo, Michael W. Kissick, Mark Ramtohul, Gordon Sands, Tracy Underwood
Affiliation: University of Surrey, Department of Medical Physics, Queen Elizabeth Hospital, Lung Cancer and Sarcoma Radiotherapy, The Clatterbridge Cancer Centre, Leo Cancer Care, Radiotherapy department, Centre LĂŠon BĂŠrard
Abstract Preview: Purpose:
Pulmonary function tests (PFTs) help assess treatment options for lung cancer patients. Conventionally, these are undertaken upright, whereas radiotherapy is administered supine. This stud...
Authors: Lei Dong, Yin Gao, Taoran Li, Michael Salerno, Boon-Keng Kevin Teo, Melissa Vila
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: A novel solution, RapidArc Dynamic-RAD (Varian Medical Systems, Palo Alto, USA) has been implemented to integrate VMAT with modulation of IMRT-like static-angle ports, including use of a dyna...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Colin Adam Doyle, Celeste Winters
Affiliation: Department of Diagnostic Radiology, Oregon Health & Science University, School of Medicine, Oregon Health & Science University
Abstract Preview: Purpose: To audit our radioactive iodine (I-131) dosimetry protocol, review dosimetry methods used at other facilities, investigate the clinical impact of I-131 dosimetry at our facility, and test the...
Authors: Alexander Choi, William Ross Green, Christine Hill-Kayser, Gary D. Kao, Michael LaRiviere, Rafe A. McBeth, Steven Philbrook
Affiliation: Department of Radiation Oncology, University of Pennsylvania
Abstract Preview: Purpose: To validate the potential of clinical deployment of an in-house AI-driven auto-segmentation tool for pediatric craniospinal irradiation (CSI) in proton therapy, with goals of reducing manual ...
Authors: Alan H. Baydush, Sarah Cummings, Jeffrey Michael Fenoli, Christy Hickerson, Lalith Kumaraswamy, Philmo Oh, Sarah B. Wisnoskie
Affiliation: Novant Health Cancer Institute, Novant Health
Abstract Preview: Purpose: To develop, validate, and commission a VMAT Total Body Irradiation (TBI) workflow by integrating publicly available resources, commercial solutions, and in-house testing to enhance treatment ...
Authors: Maria F. Chan, Indra J. Das, Xiuxiu He, Seng Boh Gary Lim, Jeonghoon Park, Yunjie Yang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: There is a need for accurate and flexible in-vivo dosimetry systems, particularly for special procedures. Effective dosimetry is crucial for dose verification and maintaining records. A new r...
Authors: Gueorgui Gueorguiev, Katia Sergieva, Filip Simeonov, Tsvetelina Todorova, Bozhidar Vladimirov
Affiliation: National Centre of Radiobiology and Radiation Protection, Queen Giovanna University Hospital
Abstract Preview: Purpose: Dosimetry audit is an essential tool enhancing confidence in the accuracy of treatment delivery and in prevention of radiation treatment incidents. Current work depicts how novel nationwide r...
Authors: Niko Ahjoniemi, Antti Kulmala, Katja Peltola
Affiliation: Clinical Research Institute HUS, Helsinki University Hospital
Abstract Preview: Purpose: To determine the backlash of a multileaf collimator (MLC) using four measurement methods: motor encoder (primary readout), linear potentiometer (secondary readout), amorphous silicon panel (p...
Authors: Theodore Higgins Arsenault, Beatriz Guevara, Rojano Kashani, Raymond F. Muzic, Gisele Castro Pereira, Alex T. Price
Affiliation: University Hospitals Seidman Cancer Center, Case Western Reserve University Department of Biomedical Engineering
Abstract Preview: Purpose: Accurate dose prediction in radiotherapy is essential for treatment planning. This study evaluates four nnUnet-based models using the OpenKBP head and neck dataset: a baseline model (Model 1)...
Authors: Jacinta E. Browne, Tzu Cheng Chao, Ajit Deveraj, Ece Ercan, Tim Leiner, Alessio Perazzolo, Michal Povazan, Jouke Smink, Camilla Vita, Spencer Waddle, Dinghui Wang
Affiliation: UniversitaĚ Cattolica del Sacro Cuore, Philips Healthcare, Mayo Clinic
Abstract Preview: Purpose:
In recent years, mid-field MRI has shown promise to meet the technical demands of cardiac imaging1. Mid-field strengths offer advantages to CMR due to shorter T1-relaxation times, lower sp...
Authors: Wesley A. Belcher, Aidan Burke, Matthew Green, Taylor Stamey
Affiliation: ECU Health, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: The purpose of this study was to determine the effect of using deep inhalation breath hold (DIBH) vs. free breathing (FB) and intensity-modulated radiation therapy (IMRT) vs. 3D for right-sid...
Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...
Authors: Ivan M. Buzurovic, Phillip M. Devlin, Evangelia Kaza, Michael John Lavelle
Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Womenâs Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Recent work in surface brachytherapy (SBT) has demonstrated the feasibility of using magnetic resonance (MR)-guidance in place of Computer Tomography (CT) in SBT planning. The purpose of this...
Authors: Tianyuan Dai, Zejun Jiang, Xiangyue Kong
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
This study aims to evaluate the reliability of SFRT-VMAT plan verification by comparing two QA methods: Portal Dosimetry (PD) and Delta4ÂŽ.
Methods:
Preteatment QA was conducted for 1...
Authors: Junsheng Cao, Luis A. Maduro Bustos, Khushdeep Singh
Affiliation: Overlook Medical Center, Atlantic Health System at Morristown Medical Center
Abstract Preview: Purpose: To evaluate the agreement between the Sun Nuclear Multi-Met Winston Lutz test (WL) and Varianâs Machine Performance Check (MPC) in assessing isocenter alignment, couch, and collimator rotatio...
Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...
Authors: Julien Forthomme, Carolina Llina Fuentes, Valentin Hamaide, Lucian Hotoiu, Rudi Labarbe, Rasmus Nilsson, Arnaud Pin, Francois Vander Stappen, Erik Traneus
Affiliation: RaySearch Laboratories AB, Ion Beam Applications SA
Abstract Preview: Purpose: Conformal FLASH achieves ultra-high-dose-rate (UHDR) proton therapy (>40 Gy/sec) by scanning a mono-energetic pencil beam through accessories (range shifter, Conformal Energy Modulator, apert...
Authors: Angela Gathers, Christina Henson, Sakuntala Jagabattuni, Mark A. Newpower
Affiliation: University of Oklahoma HSC, Department of Otolaryngology, University of Oklahoma HSC, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A previous departmental study showed an increase in ototoxicity (hearing loss) rates in head & neck cancer (HNC) patients treated with Intensity Modulated Proton Therapy (IMPT) vs. x-ray radi...
Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer
Affiliation: RaySearch Laboratories, Moffitt Cancer Center
Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...
Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. GĂśksel, GĂśrkem O. GĂźngĂśr, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan
Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman SĂśnmez Oncology Hospital
Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...
Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patientâs nose relative to two stationary reflectors on th...
Authors: Chloe Duncan, Andrew Kanawati, Peter Malek, Tess Reynolds
Affiliation: University of Sydney, Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Pedicle screw fixation, a standard spinal surgery procedure, has high misplacement rates (~40%) which decrease with surgeon experience. However, opportunities for surgical rehearsal, training...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Abid Khan, Chad Klochko, Michael J Kovalchick, Hyeok Jun Lee, Hani Nasr, Krishnan Shyamkumar, Kundan S Thind
Affiliation: Henry Ford Radiology, Wayne State University, Henry Ford Health, HFHS
Abstract Preview: Purpose: Automated vascular segmentation in interventional angiography is challenged by contrast kinetics, vessel variations, and 2D projections, limiting the effectiveness of single-model approaches....
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Childrenâs Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Childrenâs Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Childrenâs Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo
Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...
Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma
Affiliation: University of Pennsylvania, Mayo Clinic
Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...
Authors: Wei Wei, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology
Abstract Preview: Purpose: To investigate an uncertainty modeling method to improve the performance of cancer classification with the ability to produce uncertainty score.
Methods: Deep learning has achieved state-o...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectors⢠for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: Davide Brivio, Ivan M. Buzurovic, Thomas C. Harris, Desmond A. O'Farrell
Affiliation: Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Cervical cancer can be treated with a brachytherapy boost following external beam radiotherapy. One applicator option is the Advanced Gynecological Applicator "Venezia" (Elekta) hybrid, consi...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Michael Dingfelder, Homeira Faridnejad
Affiliation: East Carolina University, Department of Physics, East Carolina University
Abstract Preview: Purpose: To use Gafchromic film for measurement of the dose delivered by low-energy (2-4 MeV) protons to living cells.
Methods: Five different types of Gafchromic films were tested for dosimetry un...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: Dynamic Winston-Lutz (WL) testing provides a comprehensive framework for evaluating the accuracy of isocenter alignment. This study investigates the impact of dynamic beam modulation, such as...
Authors: James E. Bates, Benjamin Hopkins, Kirk Luca, Shadab Momin, Justin R. Roper, Soumon Rudra, Eduard Schreibmann, Bill Stokes, Tu Thi, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Swallowing dysfunctions after radiotherapy are caused by multiple factors yet are strongly associated with the irradiation of pharyngeal musculature due to its role in the initiation and comp...
Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, GaĂŤl Ndoutoume-Paquet, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson
Affiliation: DĂŠpartement de physique, de gĂŠnie physique et d'optique, UniversitĂŠ Laval, Laval University, Princess Margaret Cancer Centre, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique MĂŠdicale et de Radioprotection, Centre IntĂŠgrĂŠ de CancĂŠrologie, CHU de QuĂŠbec- UniversitĂŠ Laval et Centre de recherche du CHU de QuĂŠbec, Nuclear Medicine Department, Hospital Regional de Antofagasta
Abstract Preview: Purpose: Modelling electronic brachytherapy (eBT) sources is difficult because of the high-dose gradients and challenges associated with low-energy modelling. This study examines the accuracy of avail...
Authors: Rajeev Gupta, Shriram Ashok Rajurkar, Teerthraj Verma
Affiliation: King George's Medical University, King George's Medical University, UP
Abstract Preview: Purpose:
The volunteer deep inspiration breath hold (vDIBH) technique is used to reduce the heart dose in left breast cancer radiotherapy. Many times, it is faced that despite rigorous exercise and...
Authors: Kenneth A. Fetterly
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Among the limitations of channelized Hotelling T2 type model observers (CHO) applied to medical imaging systems is that they reduce 2D image detail to a singular value and are only applicable...
Authors: Brecca Bettcher, Tobey J Betthauser, Bradley T Christian, Sterling Johnson, Lisette LeMerise, Max McLachlan, Andrew McVea, Dhanabalan Murali, Ali Pirasteh, Matthew Zammit
Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center
Abstract Preview: Purpose: The radiotracer [18F]NAV4694 is a desirable alternative to [11C]PiB for measuring amyloid neuropathology related to Alzheimerâs disease (AD), possessing similar imaging characteristics and fa...
Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...
Authors: Shifeng Chen, Mariana Guerrero, Michael J. MacFarlane, Huijun Xu, Baoshe Zhang, Jinghao Zhou
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center
Abstract Preview: Purpose: The clinical value of surface-guided radiotherapy (SGRT) in prone breast cancer setups is much less established than in supine setups. This study explores SGRT's potential for prone breast pa...
Authors: Stella Flampouri, Edgar Gelover, William Andrew LePain, Roelf L. Slopsema, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University
Abstract Preview: Purpose: Little consideration was given to the change in dose rate (DR) observed when moving to pencil beam scanning (PBS). This study reports on DR in clinical prostate PBS plans. While dose distribu...
Authors: Yijian Cao, Jenghwa Chang, Lyu Huang
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systemsâVarianâs TrueBeam (C-arm) and Halcyon (O-ring)âfor prostate Stereotactic Body Ra...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose: To evaluate and compare dose calculation differences between Monaco and AdaptBox by TheraPanacea on AI-generated pseudo-CTs (pCTs) from a CBCT.
Methods: Dose calculations in water phan...
Authors: Christian Fiandra, Marco Fusella, Gianfranco Loi, Silvia Pesente, Lorenzo Placidi, Claudio Vecchi, Orlando Zaccaria, Stefania Zara
Affiliation: Abano Terme Hospital, University of Turin, Maggiore della CaritĂ , Tecnologie Avanzate Srl, Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abstract Preview: Purpose: Deformable-image-registration (DIR) is essential in modern radiotherapy for adaptive RT, re-irradiation, and other clinical applications. Multimodal DIR is especially important in MRI-only wo...
Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC
Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyonâs doub...
Authors: Edwin Quashie, Yun Wang
Affiliation: Indiana University Medical School, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: To provide a formal evaluation for the TrueBeam linac matching process before, during and after the commission of the newly installed TrueBeam linac which we want to match to an existing True...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: In August 2024, ZAP-X introduced automatic placement for isocenters in a DP-1010 upgrade for treatment planning. In this study, plans made by automatic placed isocenters are compared to those...
Authors: Emily Y. Hirata, Xiaoyu Sherry Liu, Evan Porter, Manju Sharma
Affiliation: University of California San Francisco, University of California, San Francisco, University of California
Abstract Preview: Purpose:
The Varian Halcyon Linear Accelerator has become increasingly popular in both community hospitals and academic institutions due to its user-friendly design and operational efficiency. This...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: DĂŠpartement de Physique, de GĂŠnie Physique et D'optique, et Centre de Recherche sur le Cancer, UniversitĂŠ Laval, DĂŠpartement de Physique, de GĂŠnie Physique et D'optique, et Centre d'optique, photonique et laser, UniversitĂŠ Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Renan Felix dos Santos, Gustavo Freire Pereira da Silva, Alessandra Tomal
Affiliation: University of SĂŁo Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de FĂsica Gleb Wataghin
Abstract Preview: Purpose: Evaluate the feasibility of a bench-top PCCT using Geant4 Monte Carlo simulations. The study applied the Geant4 framework on determining the electronic density of materials as a function of C...
Authors: Resat Aydin, Joseph Barbiere, Brett Lewis, Roland Teboh
Affiliation: HUMC, Hackensack University Medical Center
Abstract Preview: Purpose:
Accurately compensating for respiratory-induced tumor motion is critical in BgRT, where precise delineation of volumes ensures effective dose delivery. We propose an integrated approach th...
Authors: Xiangli Cui, Chunyan Fu, Man Hu, Wanli Huo, Jingyu Liu, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, Department of Oncology, Xiangya Hospital, Central South University, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose: To quantify the impact of fine-tuning strategies for pre-trained AI image generation models on glioma MRI image quality and observer performance, and to determine the optimal fine-tuning conf...
Authors: Yoonha Eo
Affiliation: Yonsei University
Abstract Preview: Purpose: To develop a fully automatic and unsupervised algorithm for estimating the Exposure Index (EI) of various Regions of Interest in X-ray imaging using advanced foundation models. Traditional EI...
Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu
Affiliation: Massachusetts General Hospital, MGH
Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...
Authors: Jianrong Dai, Jun Dang, Enzhuo Quan, Yong Sang, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital & Shenzhen Hospital / Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: The current conformity index (CI) formula is distorted for radiotherapy plans with multiple, non-enclosing targets. We redefined the volume of reference isodose (VTV) parameter in the CI form...
Authors: Pouya Azarbar, Nima Kasraie, Mahsa Shahrbabki Mofrad, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences, Tehran University of Medical Science
Abstract Preview: Purpose: PET imaging become crucial in diagnosing and managing various diseases, but its key limitation is the lack of detailed anatomical information. Integrating CT-scans with PET images enhances cl...
Authors: James M. Lamb, Dishane Chand Luximon, Jack Neylon, Rachel Petragallo, Moritz Ritter, Timothy Ritter
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, ETH Zurich, VCU Health System, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: Anomalies in cone beam computed tomography (CBCT) radiotherapy image guidance can signal treatment deviations. Repetitive review of setup image registrations by humans is inefficient, prone t...
Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou
Affiliation: University of Kentucky, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...
Authors: Shen Fu, Jun Hou, Zuofeng LI, Taize Yuan, Qingyuan Zhang, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center, ĺšżĺˇćł°ĺčżç¤ĺťé˘
Abstract Preview: Purpose: A visual feedback system is beneficial for patients to maintain consistent respiratory signal during gated radiotherapy, especially for intensity modulated proton therapy (IMPT) where motion ...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: For soft-tissue abdominal tumors, a 4D-MR may provide improved tumor tracking over the clinical standard 4D-CT. This project aims to optimize a clinically available 4D-MR pulse sequence to ac...
Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte
Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine
Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...
Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...
Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose:
MR-guided adaptive radiation therapy (MRgART) is transforming clinical workflows, requiring fast, accurate organs-at-risk (OARs) contouring. While deep learning auto-segmentation (DLAS) of...
Authors: Jue Jiang, Aneesh Rangnekar, Shiqin Tan, Harini Veeraraghavan
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences
Abstract Preview: Purpose: Clinicians often use information from FDG-PET and CT to interpret and delineate gross tumor (GTVp) and nodal (GTVn) volumes for radiotherapy planning in head and neck (HN) cancer patients. He...
Authors: Ali Ajdari, Thomas R. Bortfeld, Christopher Bridge, Gregory Buti, Marcela Giovenco, Fredrik Lofman, Gregory C. Sharp, Helen A Shih, Tugba Yilmaz
Affiliation: Massachusetts General Hospital, RaySearch Laboratories, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Defining radiation target volumes with accurate integration of the neuroanatomy is one of the major difficulties in designing glioma treatments. We developed a deep learning network for norma...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Current best practices recommend daily imaging and planning for Tandem and Ring (T&R) HDR patient plans. Accurate target delineation is a critical, yet time consuming step in this process. Th...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong
Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University
Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: J. Daniel Bourland, Christina K Cramer, Justin M. Napolitano, James D. Ververs
Affiliation: Wake Forest University School of Medicine
Abstract Preview: Purpose:
Brain metastases (BM) can be treated with linear accelerator (LINAC)-based stereotactic radiosurgery (SRS). Treatment planning for this modality has evolved over time; treatment plans typi...
Authors: Emily Hansen, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: The accuracy of SCINTIX biology-guided radiotherapy (BgRT) on the RefleXion X1 is dependent on the correct alignment of the isocenter between all subsystems, including setup lasers, kV imagin...
Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou
Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...
Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka
Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the filmâs energy dependence between kV and MV energies.
Methods: A single 8âx10â LD-V...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Smith Apisarnthanarax, Clemens Grassberger, John Kang, Yejin Kim, Justin Leu, Dominic A. Maes, Matthew J. Nyflot, Ramesh Rengan, Annemarie Shepherd, Jing Zeng
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: Reirradiation (ReRT) is a rapidly growing clinical challenge driven by better systemic therapy and longer survival, though clear guidelines for ReRT are lacking. Fitting traditional normal ti...
Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard
Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patientsâ setups. MAHR complements current image-guidance...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...
Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich
Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...
Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb
Affiliation: GenesisCare
Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Christopher Ackerman, Chang Chang, Yan-Cheng Huang, Robert Kaderka, Che Lin, Hsin-Chih Lo, Iain MacEwan, Yi-Chin Tu, James Urbanic
Affiliation: University of California San DIego, Taiwan AI Labs, National Taiwan University, California Protons Cancer Therapy Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: To investigate the performance of an existing AI beam angle prediction model on external patient datasets for liver proton treatments. The AI model was trained on datasets exclusively from on...
Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...
Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas
Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco
Abstract Preview: Purpose: Hospital readmission prediction models often rely on structured Electronic Health Record (EHR) data, overlooking critical insights from unstructured clinical notes. This study presents a mult...
Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever
Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center
Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...
Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.
Abstract Preview: Purpose: The novel machine quality assurance (QA) device nĂźFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...
Authors: Yussuf A. Abdelal, Sebastien A. Gros, Luke Layman, Anil Sethi
Affiliation: Stritch School of Medicine, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago
Abstract Preview: Purpose:
End-to-end (E2E) test is a vital QA check of the overall radiotherapy process from simulation imaging to treatment delivery. Although clinical passing criteria are available, guidelines on...
Authors: Ana Maria Barragan Montero, Damien Dasnoy, Sylvain Deffet, Valentine Dormal, Colin Gaban, Melanie Ghislaine, Valentin Hamaide, Guillaume Janssens, John A. Lee, Eliot Peeters, Danah Pross, Luciano Rivetti, Benjamin Roberfroid, Romain Schyns, Kevin Souris, Edmond S. Sterpin, Sophie Wuyckens
Affiliation: Ion Beam Applications SA, Hospital Riviera-Chablais, UCLouvain, Multitel, UniversitĂŠ Catholique de Louvain, IBA, Faculty of Mathematics and Physics, University of Ljubljana, Universite Catholique de Louvain
Abstract Preview: Purpose: Treatment planning systems (TPSs) are essential for simulating and optimizing radiotherapy treatments. However, clinical TPSs are expensive software commercialized by private companies and of...
Authors: Curtiland Deville, Rachel B. Ger, Heng Li, Todd R. McNutt
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Proton therapy patients receive quality assurance CT scans (QACTs) during treatment to verify dosimetric accuracy and determine adaptive therapy needs as proton treatments are highly sensitiv...
Authors: Charles D. Bloch, Stephen R. Bowen, Bing-Hao Chiang, Alex Egan, Eric C. Ford, Sharareh Koufigar, Dominic A. Maes, Juergen Meyer, Sharon Pai, Frank Rafie, Rajesh Regmi, Jatinder Saini, George A. Sandison, Marco Schwarz, Bishwambhar Sengupta, Tony P. Wong
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington
Abstract Preview: Purpose: This study aimed to optimize the strategy and timing of physics consults for proton prostate patients to improve the patient experience and resource utilization in our radiation oncology depa...
Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...
Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of WisconsinâMadison, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...
Authors: Shifeng Chen, Erica Fisler, Arun Gopal, Mariana Guerrero, Jason Hendershot, Kai Huang, Eric Kusmaul, Adam Schrum, Megan Steinberg, Kai Wang
Affiliation: University of Maryland School of Medicine, Department Radiation Oncology, Kaufman Cancer Center, Upper Chesapeake Medical Center, University of Maryland Medical System Central Maryland Radiation Oncology, Department of Radiation Oncology, University of Maryland Medical Center, Baltimore Washington Medical Center Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
Our goal is to develop and clinically deploy an automated planning tool using multicriteria optimization (MCO) for VMAT in prostate only, whole pelvis radiotherapy treatments.
Methods:<...
Authors: Bowen Jing, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Medical images acquired at multiple time points during neoadjuvant chemotherapy allow physicians to assess patientsâ responses and personalize treatment plans accordingly. Studies from the I-...
Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...
Authors: Fahad Alam, Douglas A Hoover, Raffi Karshafian, Andrew Loblaw, Lucas Mendez, Lucas Mendez, Gerard Morton, Humza Nusrat, Moti R. Paudel, Mackenzie Smith, Amandeep Tagger, Anton Varlukhin
Affiliation: Odette Cancer Center, Sunnybrook Health Sciences Center, Department of Anesthesiology, Temerty Medicine, University of Toronto, Department of Physics, Toronto Metropolitan University, Department of Radiation Oncology, Temerty Medicine, University of Toronto, Department of Radiation Oncology, London Health Sciences Centre
Abstract Preview: Purpose: Prostate brachytherapy utilization has declined, due in part to limitations seen with in-person training including time and space constraints in the operating room. Virtual reality addresses ...
Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu
Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection
Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...
Authors: Teh Lin, Anna Oneil
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Daisuke Kawahara, Takaaki Matsuura, Yuji Murakami, Ryunosuke Yanagida
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima
Abstract Preview: Purpose: In recent years, automation in radiation therapy planning using AI has gained significant attention to reduce the workload of treatment planners. Adaptive Radiation Therapy (ART), as a new fo...
Authors: William T. Hrinivich, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Volumetric modulated arc therapy (VMAT) planning is a computationally expensive process. In this work, we propose a reinforcement learning (RL) framework to automatically optimize dose rate a...
Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer
Affiliation: UCLA, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...
Authors: Yijian Cao, Sean T Grace, Marissa Joyce Vaccarelli
Affiliation: Northwell
Abstract Preview: Purpose:
This study investigates the dosimetric efficacy of significantly limiting gantry angles in prostate radiation therapy to as a promising strategy to maintain plan quality while enhancing ma...
Authors: Hadley Anna DeBrosse, Kevin J. Little
Affiliation: The Ohio State University
Abstract Preview: Purpose: This work examines the consistency and pattern of spatial resolution degradation in weekly quality control (QC) testing prior to CT tube failure and replacement and investigates potential cor...
Authors: Trevor McKeown, Deshan Yang, Zhendong Zhang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: Accurate delineation of liver blood vascular structures is crucial for planning and executing therapeutic interventions in liver-related medical procedures. However, current auto-segmentation...
Authors: Ted Lynch
Affiliation: Sun Nuclear, a Mirion Medical Company
Abstract Preview: Purpose: A novel ultrasound quality assurance method is presented that constructs âsynthetic spheresâ at arbitrary locations within the image frame by combining correlation length measurements from a ...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...
Authors: Jiayun Chen, Shengqi Chen, Junchao Li, Fei Liu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Tongji Medical College, Huazhong University of Science & Technology, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To assess if 3D Vane MRI can accurately depict the motion of the target volume and OARs.
Methods: This retrospective study included 54 liver cancer patients who underwent both 3D Vane MRI ...
Authors: Sara Allievi, Stefano Bonvini, Gloria Miori, Laura Orsingher, Andrea Passerini, Igor Raunig, Daniele Ravanelli, Erich Robbi, Annalisa Trianni
Affiliation: Department of Information Engineering and Computer Science, University of Trento, Vascular Surgery Department, S.Chiara Hospital, APSS, Medical Physics Department, S.Chiara Hospital, APSS
Abstract Preview: Purpose:
This study evaluates the performance of an AI-driven tool in segmenting and analyzing tissue composition in abdominal aortic aneurysm (AAA) patients, specifically focusing on the sealing z...
Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven
Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University
Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...
Authors: Zhaohui Han, Piotr Zygmanski
Affiliation: Brigham and Womenâs Hospital, Dana Farber Cancer Institute, Harvard Medical School, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Real-time motion tracking/gating are oftentimes limited to a single sagittal plane on many magnetic resonance linear accelerators (MR-Linac). Out-of-plane motion is therefore difficult to det...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Sagine Berry-Tony, Lasya Daggumati, James R Duncan, Melak Senay, Allan Thomas
Affiliation: University of Missouri-Kansas City School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: Most acquired images in FGIs are not permanently archived. In the context of modern computational prowess, novel improvements to FGI practice likely sit just under the surface of large-scale ...
Authors: Avinash Mudireddy, Nathan Shaffer, Joel J. St-Aubin
Affiliation: University of Iowa
Abstract Preview: Purpose: This work demonstrates preliminary results in training a reinforcement learning (RL) network to perform VMAT machine parameter optimization.
Methods: We implemented a policy gradient RL al...
Authors: Jean-Pierre Bissonnette, Catherine Coolens, Laura Dawson, Ryan A Kuhn, Michael Maddalena, Teo Stanescu
Affiliation: Princess Margaret Hospital, The Princess Margaret Cancer Centre - UHN, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To investigate the generation and reproducibility of 3D hypoxia maps in liver hepatocellular carcinoma (HCC) patients using data derived from an Intravoxel Incoherent Motion (IVIM) MR sequenc...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: To quantity variations in Winston Lutz (WL) test results due to different energies used in SBRT, SRT or SRS.
Methods: A WL phantom with a 6.4 mm diameter center radio-opaque sphere is used...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Hilary Louisa Byrne, Owen Thomas Dillon, Paul J. Keall, Hunor Kertesz, Ricky O'Brien, Tess Reynolds
Affiliation: University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney, Medical Radiations, School of Health and Biomedical Sciences, RMIT University
Abstract Preview: Purpose: Imaging of lung motion and function has typically required multiple volumetric CT images to create deformation vector fields (DVF) for motion and ventilation images (function). However, CT sc...