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Results for "uniform uncertainty": 4 found

Computational Prototype Single-Channel Vaginal Cylinder with Integrated Filter to Address Dose Uniformity in High-Dose-Rate Brachytherapy for Endometrial Cancer

Authors: Brett Bocian, Patrick James Jensen, Luis Augusto Perles, Christopher J. Tien

Affiliation: Yale University School of Medicine, University of Miami, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: Guidelines for dose prescriptions in endometrial cancer are based upon depth from the cylinder, traditionally 5 mm or 0 mm (i.e., surface). There are no current single-channel vaginal cylinde...

Modeling Alpha-Particle Dose from Diffusing Alpha-Emitters Radiation Therapy in Tissue with Inhomogeneous Diffusion

Authors: Lior Arazi, Gil'ad N. Cohen, Antonio L. Damato, Irene P. Zhang

Affiliation: Unit of Nuclear Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, NYU Grossman School of Medicine, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Diffusing alpha-emitters Radiation Therapy (β€œAlpha DaRT”) is a promising new radiation therapy modality for treating bulky tumors. The dose delivered by Alpha-DaRT sources is dependent on the...

Optimizing PTV Coverage in VMAT Breast Plans: A Robust Evaluation of Motion and Flash Margins

Authors: William N. Duggar, John C. White

Affiliation: UMMC, University of Mississippi Medical Center

Abstract Preview: Purpose:
To evaluate the impact of patient motion on PTV coverage for 95% and 90% target volumes in VMAT breast treatment plans and to determine the appropriate flash margins required to maintain r...

Water-Equivalent Thickness Mapping (WET-MAP) – a Potential Alternative to 4D Robust Optimization for Motion Management in Proton Treatment Planning

Authors: Duncan Henry Bohannon, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, Ahmal Jawad Zafar, Jun Zhou

Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose:
4D robust optimization, incorporating additional images (e.g., maximum inhale/exhale phases), is commonly used to account for target motion in proton treatment planning. However, the incre...