Search Submissions ๐Ÿ”Ž

Results for "viability assays": 4 found

3D Bioprinted Brain Cancer Constructs for Experimental Synchrotron Radiotherapy

Authors: John Paul Ortiz Bustillo, Elette Engels, Elrick T. Inocencio, Michael Lerch, Julia Rebecca D Posadas, Anatoly Rosenfeld, Kiarn Roughley, Moeava Tehei, Gordon Wallace, Danielle Warren, Vincent de Rover

Affiliation: Centre for Medical Radiation Physics, University of Wollongong Australia, Department of Radiology, University of the Philippines- Philippine General Hospital, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong Australia, Centre for Medical Radiation Physics, University of Wollongong, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, University of the Philippines Manila; Centre for Medical Radiation Physics, University of Wollongong Australia

Abstract Preview: Purpose: To compare the biological response through cell viability assay and fluorescence imaging of 3D bioprinted brain cancer (glioma) constructs relative to 2D monolayer and 3D spheroid culture for...

A Monte Carlo Dosimetry-Based Cell Survival Model Incorporating Spatial and Temporal Heterogeneity for Rpt Preclinical Studies

Authors: Alejandro Bertolet, Michael D. Farwell, Sarah Gitto, Victor V. Onecha, Daniel Pryma, Aladdin Riad

Affiliation: Department of Pathology and Laboratory Medicine, Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Department of Radiology, Perelman School of Medicine, Perelman School of Medicine at the University of Pennsylvania, Massachusetts General Hospital and Harvard Medical School

Abstract Preview: Purpose: Responses to ionizing radiation (IR) strongly correlate with the absorbed dose. At the cellular level, this is typically described by a linear-quadratic relationship provided the cell populat...

Evaluating the Theranostic Potential of a Novel Shark Derived Anti-MET Vnar Antibody in NSCLC

Authors: Andrew M Baschnagel, Jonathan W. Engle, Jessica E. Griffin, Gihan Gunaratne, Reinier Hernandez, Randall J Kimple, Aaron M. LeBeau, Natalie Y. Luo, Rachel Minne, Caroline M. Mork, Kwangok P Nickel, Jayden West, Madalynn R. Wopat

Affiliation: University of Wisconsin, University of Wisconsin, Department of Pathology and Laboratory Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsinโ€“Madison, University of Wisconsin - Department of Human Oncology, UW Madison, University of Wisconsin, Department of Medical Physics

Abstract Preview: Purpose: The Mesenchymal-Epithelial Transition gene (MET), a targetable cell surface receptor responsible for stimulating cell growth and proliferation, is altered in approximately 10% of non-small ce...

Induced Bystander Effect in MCF-7 Breast Cancer Cells after X-Ray Irradiation

Authors: Beatriz Allyne Dia Carandang, Chitho P Feliciano, Teresa Sy-Ortin

Affiliation: Department of Physical Sciences and Mathematics, University of the Philippines Manila, Health Physics Research Section, Atomic Research Division, Department of Science and Technology-Philippine Nuclear Research Institute (DOST-PNRI), Graduate School, University of Santo Tomas

Abstract Preview: Purpose: To investigate the X-ray radiation-induced bystander effect (RIBE), where unirradiated cells mimic the responses of directly irradiated cells, in MCF-7 breast cancer cells in vitro to underst...