Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu
Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell
Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...
Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington
Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...
Authors: Hannah Grover, Andrew J. Sampson
Affiliation: Oregon Health & Science University, UT Health San Antonio
Abstract Preview: Purpose: The goal of this work was to quantify the dosimetric impact of iodinated contrast on fibroglandular breast tissue to better inform clinical risk and benefit assessments when determining the m...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Dean Darnell, Iyanna M Lewis, Francesco Ria, William Paul Segars
Affiliation: Duke University, Duke University Medical Physics Graduate Program, Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University Medical Center
Abstract Preview: Purpose: To estimate radiation dose to pediatric patients during standard CT imaging of the chest and abdomen and determine how dose varies with patient age, height and weight and how measurements com...
Authors: Ehsan Abadi
Affiliation: Duke University
Abstract Preview: N/A...
Authors: Clemens Grassberger, David (Bo) McClatchy, Harald Paganetti
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Massachusetts General Hospital
Abstract Preview: Purpose: While randomized controlled trials (RCTs) are the gold standard for demonstrating efficacy, nearly 50% of late-stage clinical trials fail to meet their endpoint. Tools to study the design of ...
Authors: James M. Balter, Lando S. Bosma, Jorge Tapias Gomez, Nishant Nadkarni, Mert R Sanbuncu, William Paul Segars, Ergys D. Subashi, Neelam Tyagi, Harini Veeraraghavan
Affiliation: University of Michigan, The University of Texas MD Anderson Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Cornell University, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Develop patient-specific virtual digital twin (VDT) cohorts modeling physically realistic spatio-temporal gastrointestinal (GI) organs (stomach and duodenum) digestive motion.
Methods: Pat...
Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...
Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...
Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei
Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...