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Results for "vivo µspect": 4 found

Development of Preclinical Multiscale Dosimetry for Beta-Particle Emitting Radionuclide in Radiopharmaceutical Therapy

Authors: Adedamola Adeniyi, Bryan Bednarz, Malick Bio Idrissou, Reinier Hernandez, Ohyun Kwon, Brian W. Miller, Zachary S Morris, Maya Takashima, Jamey Weichert

Affiliation: Departments of Radiation Oncology and Medical Imaging, University of Arizona, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Radiology, School of Medicine and Public Health, University of Wisconsin–Madison, Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin–Madison

Abstract Preview: Purpose: As radiopharmaceutical therapy (RPT) becomes more prevalent in clinical applications, understanding dose-response relationships in the tumor microenvironment (TME) and normal tissues is essen...

Evaluating the Theranostic Potential of a Novel Shark Derived Anti-MET Vnar Antibody in NSCLC

Authors: Andrew M Baschnagel, Jonathan W. Engle, Jessica E. Griffin, Gihan Gunaratne, Reinier Hernandez, Randall J Kimple, Aaron M. LeBeau, Natalie Y. Luo, Rachel Minne, Caroline M. Mork, Kwangok P Nickel, Jayden West, Madalynn R. Wopat

Affiliation: University of Wisconsin, University of Wisconsin, Department of Pathology and Laboratory Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin–Madison, University of Wisconsin - Department of Human Oncology, UW Madison, University of Wisconsin, Department of Medical Physics

Abstract Preview: Purpose: The Mesenchymal-Epithelial Transition gene (MET), a targetable cell surface receptor responsible for stimulating cell growth and proliferation, is altered in approximately 10% of non-small ce...

Optically Guided Speculum for Needle or Other Probe-Based Interventions in Small Animals

Authors: Michael B. Altman, Marlene Campos Guerrero, Stephanie Markovina, Aaron Silvus

Affiliation: Washington University School of Medicine

Abstract Preview: Purpose: Currently, fluid injections or needle biopsies in small animals are conducted with limited optical guidance introducing an inherent risk of infecting or injuring the animal and limits precisi...

Optimal Choice of Companion Radiotracer for TAT 225Ac-Mti-201.

Authors: Vinay K Banka, Mikalai Budzevich, William R. Gibbons, Mark L. McLaughlin, Jacob Moriarty, Eduardo G. Moros, David L. Morse, Christopher J. Tichacek, Thad J. Wadas

Affiliation: Modulation Therapeutics Inc, Moffitt Cancer Center, University of Iowa

Abstract Preview: Purpose: A targeted alpha therapy drug, 225Ac-MTI-201, has been developed targeting the Melanocortin 1 Receptor for metastatic uveal melanoma and is currently in FIH clinical trials. Since alpha emiss...