Authors: John J. DeMarco, Farideh Pak, Olivia Grahm C Valadie
Affiliation: Cedars Sinai, Cedars-Sinai, Cedars-Sinai Medical Center
Abstract Preview: Purpose: To investigate the performance of the Integral Quality Monitor (IQM) device for patient-specific QA, focusing on segment-by-segment signal evaluation compared to cumulative signal evaluation....
Authors: Chloe Doen Kim, Patricia E. Lindsay, Bern Norrlinger, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Queen's University, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To propose a method to check the consistency of VMAT delivery on linear accelerator (LINAC) with a commercial three-dimensional array device. The method is insensitive to the correction facto...
Authors: Edward D. Brandner, Weihua Fu, M. Saiful Huq, Ronald John Lalonde, Kiran Mehta, Hima Bindu Musunuru, Yongqian Zhang
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pittsburgh School of Medicine and UPMC Hillman CancerCenter
Abstract Preview: Purpose: Treatment of diffuse and extensive involvement of the skull by malignancy presents a difficult challenge for radiation therapy. This study reports preliminary experience of a modified volumet...
Authors: Liqin HU, Tao He, Jing JIA, Pengcheng LONG, Wei Meng, Yang Yuan
Affiliation: SuperAccuracy Science & Technology Co. Ltd.
Abstract Preview: Purpose: A multi-criteria optimization method based on reinforcement learning and adaptive boosting(RLAB MCO) has been developed to enhance radiotherapy plan quality by offering reasonable and effecti...
Authors: Chuan He, Anh H. Le, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, Cedars-Sinai
Abstract Preview: Purpose: To develop a non-measured and DVH-based (NMDB) IMRT QA framework integrating machine learning (ML) to classify lung SBRT VMAT plans prone to delivery errors
Methods: 560 Eclipse AcurosXB l...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Andrew Huang, Jonathan Huang, Andrew S Kennedy, Ellie Grace Kong, Ajay Zheng
Affiliation: New York Proton Center, Centennial Medical Center, Executive Medical Physics Associates, Sarah Cannon Cancer Institute, Belmont University
Abstract Preview: Purpose:
Lung stereotactic body radiotherapy (SBRT) is the standard of care for early-stage lung cancer. Respiratory phase gating can be applied to mitigate motion-induced effects. The purpose of t...
Authors: Kaile Li, Esmail Parsai
Affiliation: Alexander T. Augusta Military Medical Center, Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To evaluate the sensitivity of the portal dosimetry system with the Arc CHECK system at identical Volumetric Modulated Arc Therapy (VMAT) setup
Methods: An Arc CHECK system from Sun Nuclea...
Authors: Alan H. Baydush, Sarah Cummings, Jeffrey Michael Fenoli, Christy Hickerson, Lalith Kumaraswamy, Philmo Oh, Sarah B. Wisnoskie
Affiliation: Novant Health Cancer Institute, Novant Health
Abstract Preview: Purpose: To develop, validate, and commission a VMAT Total Body Irradiation (TBI) workflow by integrating publicly available resources, commercial solutions, and in-house testing to enhance treatment ...
Authors: Nrusingh C. Biswal, Sally Cheston, Sung-Woo Lee, Weiguang Yao, Baoshe Zhang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: The deep inspiration breath-hold (DIBH) technique in left breast radiation reduces doses to critical organs such as the heart, left lung, and left anterior descending artery (LAD). With the a...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Nicholas Pierre Nelson, Ryan G. Price, Prema Rassiah, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To investigate the feasibility and clinical implications of creating customized workflows in a new SGRT system: LUNA 3D (LAP, Florida).
Methods: Three clinical SGRT workflows were designed...
Authors: Chase Cochran, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...
Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav
Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)
Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...
Authors: Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Development of a novel spatially fractionated radiotherapy (SFRT) lattice deployment method featuring a large high-dose sphere at the tumor’s center, surrounded by smaller diameter spheres. W...
Authors: Ian J. Butterwick, Sumudu Katugampola, ChangSeon Kim, Evan G. Meekins, Zhengdong Zhang
Affiliation: Mount Sinai Beth Israel, Gesinger Medical Center, Geisinger Medical Center
Abstract Preview: Purpose: To evaluate the dosimetric impact of enhanced dynamic leaf gap (EDLG) modeling in Eclipse V18.0 on small-field dosimetry within VMAT plans.
Methods: Plans with small fields (1 cm x 1 cm to...
Authors: Megan E. Daly, Ryan D. Hernandez, Abriel J. Horak, Soo Kyoung Kim, Peter C. Park, Dwaine O. Spence, Payton H. Stone, Cari L. Wright
Affiliation: UC Davis Cancer Center
Abstract Preview: Purpose: To evaluate a fallback planning workflow used for cross-modality treatment planning and delivery between helical Tomotherapy and volumetric modulated arc therapy (VMAT) using conventional L-s...
Authors: Min Su
Affiliation: Mount Sinai School of Medicine
Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...
Authors: Eva Lee, R. Lee MacDonald, Alasdair Syme, Christopher G. Thomas
Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health, Dalhousie University, Nova Scotia Health
Abstract Preview: Purpose:
Dynamic couch rotation in radiotherapy offers dosimetric benefits, however patient comfort remains a concern. This study investigates couch kinematics in trajectory-based radiotherapy plan...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: Dynamic Winston-Lutz (WL) testing provides a comprehensive framework for evaluating the accuracy of isocenter alignment. This study investigates the impact of dynamic beam modulation, such as...
Authors: Sarah Burleson, Antonio L. Damato, Yabo Fu, Laura Happersett, Tianfang Li, Xiang Li, Himanshu Nagar, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: An iodinated hydrogel perirectal spacer, injected between the prostate and rectum, reduces rectal high-dose exposure during prostate SBRT. We assessed the feasibility of tracking the spacer a...
Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...
Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa
Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...
Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...
Authors: Bingqi Guo, Ping Xia
Affiliation: Cleveland Clinic
Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a “GRID” or “lattice” of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: Maria Jose Almada, Oscar Apaza, Carlos Bohorquez, Ezequiel Cabrera, Rogelio Diaz Moreno, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, FaMAF, UNC, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA employs gamma analysis to verify the planned versus delivered dose. Evaluating the effectiveness of PSQA techniques in identifying errors is crucial. This study aims to incorporate ML...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Kenny Guida, Hongyu Jiang, Harold Li, Hem Bahadur Moktan Tamang
Affiliation: University of Nebraska Medical Center, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Varian Eclipse v18.0 introduced Enhanced Leaf Model (ELM) of MLC, which provides better dose calculation accuracy than original DLG-based MLC model. The leaf-gap (LG) parameter for ELM repres...
Authors: Liu Hong, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: During treatment delivery on TrueBeam platform 2.7, Triggered Imaging (TI) enables kV images acquisition at regular intervals and Auto Beam Hold (ABH) provides beam pausing if the target is m...
Authors: Justus Adamson, John Ginn, Yongbok Kim, Ke Lu, Trey Mullikin, Xiwen Shu, Chunhao Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose:
To develop a knowledge-based deep model for synthetic CT (sCT) generation from a single MR volume in frameless radiosurgery (SRS), eliminating the need for CT simulation prior to the SRS d...
Authors: Yao Chen, Lesley A Jarvis, Allison Matous, Rongxiao Zhang
Affiliation: Dartmouth College, University of Missouri, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: Precise patient positioning is critical in accelerated partial breast irradiation (aPBI) to ensure accurate dose delivery to the tumor bed while minimizing exposure to surrounding healthy tis...
Authors: Issra Rashed, Jennie Wilder, Jingeng Zhu
Affiliation: Rush Riverside Cancer Institute, Advanced Oncology Solutions (AOS) Varian, a Siemens Healthineers company
Abstract Preview: Purpose: Develop a method to plan and deliver homogeneous dose to Craniospinal(CS) irradiation on Linear Accelerator.
Methods: Three treatment planning volumes (PTV) are created in sequence from su...
Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (≥6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...
Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...
Authors: Danielle Renee Daiger, Nicholas N. Sperling
Affiliation: University of Toledo, University of Toledo Medical Center
Abstract Preview: Purpose:
To retrospectively evaluate the impact of planned delivery time on plan quality metrics for breath-hold VMAT SBRT thoracic cancer patients.
Methods:
Patients treated for SBRT thoraci...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba
Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center
Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...
Authors: Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Edward L. Clouser, Yi Rong, Jun Tan, Jennifer Yan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
To identify planning techniques that consistently result in robust VMAT-TBI plans that allow for larger patient setup errors.
Methods:
Conventional planning method often results in p...
Authors: Karam Ayoub, Aaron B Hesselson, Ronald C McGarry, Joshua Misa, Damodar Pokhrel
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Cardiology
Abstract Preview: Purpose: Noninvasive stereotactic body radiosurgery (SBRS) is emerging treatment option for advanced heart failure patients with refractory-ventricular tachycardia (rVT) who experienced recurrent impl...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Bulent Aydogan, Xiaochuan Pan, Erik Pearson, Zheng Zhang
Affiliation: The University of Chicago
Abstract Preview: Purpose: Motion management remains one of the significant challenges in external beam radiation therapy (RT). We are developing time-resolved cone-beam computed tomography (trCBCT) for imaging during ...
Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West
Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma
Abstract Preview: Purpose: To simulate total-body-irradiation (TBI) with field-in-field treatment planning techniques and test portal dosimetry for dose verification and quality assurance.
Methods: CT images of full...
Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk
Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center
Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...
Authors: Yunfeng Cui, Joseph P. Kowalski, Qiuwen Wu, Yibo Xie
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: A Varian Ethos/Halcyon linac was recently commissioned in our clinic and was used to treat head and neck cancer patients. The purpose of this study is to compare treatment plan quality and de...
Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.
Methods: A commercial rotational table (CDR Equilibrium®) is r...
Authors: Jameson T. Baker, Sean T Grace, Cindy Pham, Michael A. Trager
Affiliation: Northwell
Abstract Preview: Purpose:
In VMAT planning, increasing complexity in MLC motion and modulation may improve dose distributions and OAR sparing while maintaining PTV coverage. However, increasing complexity can creat...
Authors: Avinash Mudireddy, Nathan Shaffer, Joel J. St-Aubin
Affiliation: University of Iowa
Abstract Preview: Purpose: This work demonstrates preliminary results in training a reinforcement learning (RL) network to perform VMAT machine parameter optimization.
Methods: We implemented a policy gradient RL al...