Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou
Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica
Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...
Authors: Yidong Yang, Haolin Zhan
Affiliation: Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop a fast low-dose method for beam blocker-based CBCT scatter correction and evaluate image quality in phantom study.
Methods: The full number of scatter projections were collected...
Authors: Wenhua Cao, Xianjin Dai, PhD, Hadis Moazami Goudarzi, Gino Lim, Miaolan Xie, Lei Xing, Lewei Zhao
Affiliation: University of Chicago Booth School of Business, Department of Radiation Oncology, Stanford University, Department of Industrial Engineering, University of Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) delivers a continuous dose of radiation during gantry rotation. 4π is a non-coplanar technique used for advanced proton therapy delivery. This work proposes a hybrid ...
Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...
Authors: Ahad Ollah Ezzati, Yile Fang, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: With breast cancer being one of the most prevalent cancers, regular screening is an effective strategy to mitigate the risk of malignancy. However, conventional energy-integrating detector (E...
Authors: Aman Anand, Jonathan B. Ashman, Martin Bues, Brady S. Laughlin, Lisa McGee, Justin Pettit, Fan Yang, Libing Zhu
Affiliation: Department of Radiation Oncology Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: Proton therapy (PT) offers significant clinical and economic benefits across various cancers, whereas it also has faced skepticism due to its historically high costs and perceived overuse in ...
Authors: James R Duncan, Nikhat Fatima Mansoori, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Collimation during fluoroscopically-guided interventions (FGIs) can not only reduce radiation exposure to patients and personnel but also improve image quality. Nonetheless, there are concern...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The Ohio State University James Cancer Hospital, The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: Accessibility is a topic of increasing importance in many fields, and medical physics is no exception. While the traditional educational pathway presents a plethora of challenges for the visu...
Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Francia Romero, Niara Rowe, Roland Teboh
Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center
Abstract Preview: Purpose: Daily use and reliance on the auto registration feature requires a performance check. Clinical application of auto registration is performed without a selected region of interest (ROI), requi...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Xianjin Dai, PhD, Zhuoran Jiang, Lei Ren, Lei Xing, Zhendong Zhang
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, Stanford University, Duke University, Stanford University
Abstract Preview: Purpose: Unsupervised deep learning has shown great promise in deformable image registration (DIR). These methods update model weights to optimize image similarity without necessitating ground truth d...
Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu
Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust
Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...
Authors: Maria F. Chan, Indra J. Das, Xiuxiu He, Seng Boh Gary Lim, Jeonghoon Park, Yunjie Yang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: There is a need for accurate and flexible in-vivo dosimetry systems, particularly for special procedures. Effective dosimetry is crucial for dose verification and maintaining records. A new r...
Authors: Julien Forthomme, Carolina Llina Fuentes, Valentin Hamaide, Lucian Hotoiu, Rudi Labarbe, Rasmus Nilsson, Arnaud Pin, Francois Vander Stappen, Erik Traneus
Affiliation: RaySearch Laboratories AB, Ion Beam Applications SA
Abstract Preview: Purpose: Conformal FLASH achieves ultra-high-dose-rate (UHDR) proton therapy (>40 Gy/sec) by scanning a mono-energetic pencil beam through accessories (range shifter, Conformal Energy Modulator, apert...
Authors: Justus Adamson, Mu Chen, Ke Lu, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Yaogong Zhang, Haipeng Zhao, Haiming Zhu, Yuchun Zhu
Affiliation: Shanghai Dacheng Medical Technology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: In filtered back-projection (FBP) reconstruction, conventional filters often reduce noise at the expense of high-frequency details, leading to structural details loss. To address this limitat...
Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. Göksel, Görkem O. Güngör, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan
Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman Sönmez Oncology Hospital
Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...
Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese
Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory
Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...
Authors: Ana Laura Burin, Maysa Müller Ferreira Gesserame, David Alexander Urbina Leal, Ilca Marli Moitinho Amaral Medeiros, Silas Leonel Pereira Miranda, Thuany Corrêa Nogueira, Maria da Penha Alburquerque Potiens, Pedro Henrique Ricardo, Maria Eduarda Zaganin Rigo, Orlando Rodrigues, Priscila Santos Rodrigues, Wilmmer Alexander Arcos Rosero, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Cristhian Ferreira Talacimon, Paulo Victor dos Santos Tavares, Lara El Hajj Teodoro, Carlos Alberto Zeituni, José Neres de Almeida
Affiliation: IPEN - USP
Abstract Preview: Purpose: Perform three-dimensional dosimetry of radioactive gold nanoparticles (¹⁹⁸AuNPs) using Fricke xylenol gel (FXG), aiming to determine the dose distribution and evaluate the method's effectiven...
Authors: Petr Bruza, David J. Gladstone, Austin Sloop, Rongxiao Zhang
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Health
Abstract Preview: Purpose: UHDR-specific probes are becoming available on the market but often demand high costs and long order times. The reduced sensitivity of these probes often imposes challenges when measuring con...
Authors: Hsiao-Mei Fu, Shih-Ming Hsu, Chia-Ting Lee, Shih-Hua Liu, Tsung-Yu Yen
Affiliation: National Yang Ming Chiao Tung University, Mackay Memorial Hospital
Abstract Preview: Purpose: The Automatic Lower Dose Objective (ALDO) is a unique function designed to achieve 98% relative coverage across all targets in automated SRS treatment planning (HyperArc planning). This study...
Authors: Kristina Bjegovic, Yong Chen, Lucia Rodriguez Gonzalez, Marti Roper, Liangzhong Xiang
Affiliation: University of California, Irvine, University of California Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is an increasingly popular cancer treatment due to its precision, enabled by the Bragg Peak (BP), which minimizes side effects. This profile necessitates in-patient localizatio...
Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington
Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: To investigate the effect of variation in the α/β of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...
Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center
Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...
Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum
Affiliation: Osaka University, Texas A&M University
Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...
Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling
Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...
Authors: Arjit K. Baghwala, Devin J. Olek, Parth K. Patel, Ramiro Pino, Adam Yanez
Affiliation: Houston Methodist Hospital, Kaiser Permanente
Abstract Preview: Purpose: The Halcyon beam model in Eclipse is immutable and only includes output factors (OF) for fields down to 1x1 cm2. The TPS must extrapolate OFs for smaller fields used in stereotactic (SRS/SBRT...
Authors: Justus Adamson, Wesley Andrew Cunningham, Chang-Sei Kim, Yeongoh Ko
Affiliation: Duke University, Chonnam National University, Duke University Medical Center
Abstract Preview: Purpose: Toxicity to bowel remains a challenge for radiotherapy, particularly for abdominal SBRT . We propose a noninvasive method to reposition bowel using a remote magnetic navigation system (RMNS) ...
Authors: Denis Bergeron, Larry A. DeWerd, Sean Jollota, Peyton Alexandra Lalain, Likhitha Polepalli
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, National Institute of Standards and Technology
Abstract Preview: Purpose: 90Y is a challenging radionuclide to measure because it is a pure beta-emitter and is typically quantified using a radionuclide calibrator. These devices, such as the Capintec model used in t...
Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan
Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem
Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...
Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Dylan Mather, Akira Nishikori, Daniel W Shin
Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA
Abstract Preview: Purpose: To validate the performance a deep learning reconstruction (DLR) algorithm in an anatomical background compared to a uniform phantom background.
Methods: An analytic forward projection mod...
Authors: Zong Fan, Fan Lam, Hua Li, Rita Huan-Ting Peng, Yuan Yang
Affiliation: University of Illinois at Urbana Champaign, University of Illinois at Urbana-Champaign, Washington University School of Medicine, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Accurate lesion segmentation in MRI is critical for early diagnosis, treatment planning, and monitoring disease progression in various neurological disorders. Cross-site MRI data can alleviat...
Authors: Matthew R. Hoerner, Allison Shields
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose: To investigate the quality and clinical utility of chest x-rays synthesized from CT scans (sCXR).
Methods: Five helical chest CT exams were chosen for evaluation: this cohort represented a...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the film’s energy dependence between kV and MV energies.
Methods: A single 8’x10’ LD-V...
Authors: Chandrasekhar Kota
Affiliation: Christiana Care Hospital
Abstract Preview: Purpose: To reflect on the present and future role of Medical Physics in the Oncoverse.
Methods: Oncoverse is the rapidly evolving and expanding ecosystem of all things related to cancer. The Medic...
Authors: Dalton Griner, Kathryn L. Kolsky, Joseph John Lucido, Andrew J. Veres
Affiliation: Mayo Clinic
Abstract Preview: Purpose: This project aimed to automate a complex and time-consuming employee scheduling process. By replacing the traditional manual method with a multi-criteria optimization-based system (MCO), the ...
Authors: Palanisamy Karunanithi, Karthikeyan Perumal, Siva Subramanian Vadivel
Affiliation: Dr. Kamakshi Memorial Hospital
Abstract Preview: Purpose:
Recent advancements in high dose-rate (HDR) brachytherapy include the image guidance, new applicators, and dose calculation algorithms. Brachytherapy has steep dose gradient, hence relativ...
Authors: Yussuf A. Abdelal, Sebastien A. Gros, Luke Layman, Anil Sethi
Affiliation: Stritch School of Medicine, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago
Abstract Preview: Purpose:
End-to-end (E2E) test is a vital QA check of the overall radiotherapy process from simulation imaging to treatment delivery. Although clinical passing criteria are available, guidelines on...
Authors: Akire Trestrail
Affiliation: University of Wisconsin
Abstract Preview: Purpose: To investigate the feasibility of using 125I as a HDR directional brachytherapy source.
Methods: Monte Carlo (MC) simulations were performed using the EGSnrc software toolkit. Dose rate di...
Authors: Estelle Batin, Michael A. Carlson, Nilendu Gupta, Zachary X. Richards, Diana Shvydka
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center
Abstract Preview: Purpose: With an increase in world-wide proton treatment availability, patients sometimes are transferred between proton and photon modalities. Among the main reasons for modality shifts are proton be...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey, Taylor Ransom
Affiliation: Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose: Proton pencil beam scanning can reduce normal tissue dose but is highly sensitive to setup, anatomical changes, and range variations. These uncertainties may compromise target coverage and or...
Authors: Ramesh Boggula, Jay W. Burmeister, Michael Joiner
Affiliation: Wayne State University, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine
Abstract Preview: Purpose: Recent advances in large language models such as ChatGPT offer new possibilities for supplementing traditional teaching methods. In this study, we developed a custom GPT-powered tool freely a...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Usha Robins Abraham, Monique Lockhart Chisem, Alonso N. Gutierrez, Janos Juhasz, Michael Leyva, Carlos M. Rivera, Ranjini P. Tolakanahalli, Vanessa Vega Fleites
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose:
Accurate breath hold (BH) gated treatments rely heavily on patient cooperation. Maintaining consistent breath-hold levels can be challenging for patients. Surface image guidance (SGRT) is ...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Hina Saeed, Gagandeep Saini, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the robustness of DynamicARC proton therapy plans for lung and prostate cancer, comparing small spot size (SS) and large spot size (LS) plans under nominal and worst-case...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...
Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center
Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.
Methods: Clonogenic cell survival w...
Authors: Zijia Guo, Viktor Haase, Michael F. McNitt-Gray, Frederic Noo
Affiliation: Siemens Healthineers, University of Utah, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: The attenuation values in CT hold strong potential for disease diagnosis. However, they lack reliability, which has limited their use to clinical trials where variability can be controlled. S...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...