Authors: John Paul Ortiz Bustillo, Elette Engels, Elrick T. Inocencio, Michael Lerch, Julia Rebecca D Posadas, Anatoly Rosenfeld, Kiarn Roughley, Moeava Tehei, Gordon Wallace, Danielle Warren, Vincent de Rover
Affiliation: Centre for Medical Radiation Physics, University of Wollongong Australia, Department of Radiology, University of the Philippines- Philippine General Hospital, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong Australia, Centre for Medical Radiation Physics, University of Wollongong, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, University of the Philippines Manila; Centre for Medical Radiation Physics, University of Wollongong Australia
Abstract Preview: Purpose: To compare the biological response through cell viability assay and fluorescence imaging of 3D bioprinted brain cancer (glioma) constructs relative to 2D monolayer and 3D spheroid culture for...
Authors: David Chighvinadze, Lisa Czaplicki, Jeremy D. Donaghue, Lama K. Muhieddine Mossolly
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic Strongsville, Cleveland Clinic Fairview
Abstract Preview: Purpose:
Current electron block generation requires manual cutting of stryofoam and placement for pouring of the block which can lead to possible miscutting of blocks, and non-accurate rotations co...
Authors: John P. Aris, Wesley E. Bolch, Madison Bushloper, Lauren E Ellis, Adam Grey Haneberg, Elizabeth Martin, Bonnie N. C. President, Andrew Robert Sforza, Alexander Zorrilla
Affiliation: Johns Hopkins University, Biomedical Engineering, University of Florida
Abstract Preview: Purpose: To develop six additional high-fidelity 3D models of kidney renal cortical labyrinth from H&E-stained histology slides to support radiation dosimetry in radiopharmaceutical therapies (RPTs).<...
Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Sixue Dong, Weigang Hu, Jiazhou Wang, Zhen Zhang
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the dosimetric benefits and treatment efficiency of different beam configurations in 4Ï non-coplanar VMAT for SBRT in recurrent head and neck tumors
Method...
Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou
Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica
Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...
Authors: Bas W. Raaymakers, Mario Ries, Paris Tzitzimpasis, Cornel Zachiu
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, University Medical Center Utrecht, UMC Utrecht
Abstract Preview: Purpose: Radiation pneumonitis affects approximately 10-30% of lung cancer patients treated with radiation therapy (RT), posing a significant dose-limiting factor. Recently developed CT-ventilation me...
Authors: Jingyuan Chen, Sheng Li, Tianming Liu, Wei Liu, Zhengliang Liu, Zhong Liu, Daniel Ma, Samir H. Patel, Guangya Wang, Yunze Yang
Affiliation: University of Miami, Mayo Clinic, School of Data Science, University of Virginia, School of Computing, University of Georgia, Department of Radiation Oncology, Mayo Clinic, Institute of Western China Economic Research, Southwestern University of Finance and Economics
Abstract Preview: Purpose:
Traditional patient outcome analyses relied heavily on conventional statistical models that primarily elucidate correlation rather than causal relationships. In this study, we aim to ident...
Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong
Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian
Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithmsâ (Radfo...
Authors: Hao Peng, Yajun Yu
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel ablative radiation dosing scheme developed by our institution. This study aims to establish a regression...
Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr
Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...
Authors: Aaron Conard, Victoria Croog, Marie Gurka, Lan Lin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose:
This study evaluates the utility of the Active Breathing Coordinator (ABC) and Surface Guided Radiation Therapy (SGRT) techniques in implementing Deep Inspiration Breath Hold (DIBH) for le...
Authors: Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The recently introduced CMS regulation on CT dose and image quality mandates the use of global noise as the metric for image quality assessment. The regulation cites two methods for calculati...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To evaluate image qualityâincluding noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)âon the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Angela Jia, Rojano Kashani, Kyle O'Carroll, Alex T. Price, Adithya Reddy, Atefeh Rezaei, Daniel E Spratt, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To evaluate the effect of unedited AI-generated contours used for online adaptive radiotherapy (FLOW-ART) on the plan quality of prostate treatments as compared to non-adaptive (non-ART) proc...
Authors: Nebi Demez, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Treatment plans on the ViewRay MRIdian are often planned with the target placed off isocenter due to the proximity of the bore to the patient, allowing for limited shifts. This is especially ...
Authors: Jamie s Baker, Sam Beddar, Mahsa Dehghanpour, Ariel MT Hoang, Emma Holliday, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Josie S Ruzek, Gabriel O. Sawakuchi
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, niversity of Texas MD Anderson Cancer Center School of Health Professions, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center School of Health Professions
Abstract Preview: Purpose: This study aims to evaluate the dosimetric impact on organs at risk (OAR) of small versus large spot sizes when treating pelvic cancer patients with pencil beam scanning (PBS) proton therapy....
Authors: Rex A. Cardan, Richard A. Popple
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose:
Compliance with TG 263 naming conventions for target structures in radiation oncology remains a challenging task due to the complexity and variability of the protocol. Traditional validati...
Authors: Yunxiang Li, Hua-Chieh Shao, Chenyang Shen, Jing Wang, Jiacheng Xie, Shunyu Yan, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate liver deformable motion tracking is essential in image-guided radiotherapy to enable precise tumor targeting during treatment. We developed a conditional point cloud diffusion model ...
Authors: Jenghwa Chang, Kuan Huang, Lyu Huang, Jason Lima, Jian Liu, Farzin Motamedi
Affiliation: Northwell, Department of Computer Science and Technology, Kean University, Physics and Astronomy, Hofstra University, Hofstra University Medical Physics Program
Abstract Preview: Title: A Deep Learning Approach to the Prediction of Gamma Passing Rates in VMAT Radiotherapy Plans for Adaptive Treatment.
Purpose: This study aims to develop a deep learning algorithm to predict ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: A challenge for dual energy CBCT is that noise and residual errors in material decomposition steps can become amplified when forming low energy, high contrast virtual mono-energetic images (V...
Authors: Suman Gautam, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-speciïŹc quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Gregory Szalkowski, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Respiratory motion management is crucial for accurate radiation delivery to moving targets while protecting healthy tissue, relying on time-resolved volumetric imaging and continuous deformab...
Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Jamieson Baker, Emel Calugaru, Yijian Cao, Jenghwa Chang, Jessica Jung, Jian Liu, Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke
Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health, Hofstra University Medical Physics Program
Abstract Preview: Purpose: Our hospital network has options to treat recurrent glioblastoma (GBM) with surgically targeted Cesium-131 brachytherapy, external beam stereotactic radiotherapy (SRT) with Varian TrueBeam, H...
Authors: Shifeng Chen, Mariana Guerrero, Brian A. Hrycushko, Kai Huang, Kai Jiang, Narottam Lamichhane, Paul M. Medin, Elizabeth Nichols
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: Unloaded needle catheters, if not handled properly, pose a risk for channel misconnection in interstitial high dose rate (iHDR) brachytherapy. This study aims to investigate the dosimetric im...
Authors: Chin-Cheng Chen, Chia-Ho Hua, Christopher J. Kutyreff, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: A dosimetric study was conducted to determine the optimal field parameters for a commercially available small-field applicator (SFA) used in spot-scanning proton stereotactic radiosurgery, pa...
Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang
Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...
Authors: Yidong Yang, Haolin Zhan
Affiliation: Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop a fast low-dose method for beam blocker-based CBCT scatter correction and evaluate image quality in phantom study.
Methods: The full number of scatter projections were collected...
Authors: William N. Duggar, Li Yuan
Affiliation: University of Mississippi Medical Center
Abstract Preview: Purpose:
Radiation Oncology departments typically utilize various systems from different vendors. Ensuring the integrity and correctness of data during transfers between these systems is essential ...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
This study aimed to retrospectively evaluate dose reduction efforts in past five years using acquisition-level data and to compare the results with ACR achievable dose (AD) and dose refere...
Authors: Huay Din, Grace Jianan Gang, Grace Hyun Kim, Michael F. McNitt-Gray, Joseph W. Stayman, Yijie Yuan
Affiliation: Johns Hopkins University, John Hopkins University, University of Pennsylvania, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose:
Radiomics rely on quantitative features to discern underlying biological signatures. However, feature dependence on the imaging systems themselves hampers the creation of reproducible and ...
Authors: Benito De Celis Alonso, Braian Adair Maldonado Luna, Gerardo Uriel Perez Rojas, RenĂ© Eduardo RodrĂguez-PĂ©rez, Kamal Singhrao
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla
Abstract Preview: Purpose: Artificial Intelligence (AI)-generated synthetic CT (sCT) images can be used to provide electron densities for dose calculation for online adaptive MRI-guided stereotactic body radiotherapy (...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2Dâ3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Christos Ilioudis, Marios Myronakis, Sotirios Raptis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Information and Electronic Engineering, International Hellenic University (IHU)
Abstract Preview: Purpose: This study presents a radiomics-driven, machine learning framework developed to predict the possibility of Radiation Pneumonitis (RP), as a side effect of radiation therapy in lung cancer pat...
Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...
Authors: B. Gino Fallone, Keith D. Wachowicz, Mark G. Wright, Jihyun Yun
Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com
Abstract Preview: Purpose: This work focusses on a hybrid Principal Component Analysis (PCA) based MR acceleration method for prospectively acquired undersampled data on a hybrid MR-Linac system for real-time target-tr...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Allison Dalton, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: External-beam Accelerated Partial Breast Irradiation (APBI) using stereotactic-body radiotherapy (SBRT) is increasingly adopted as an alternative to whole-breast radiation, offering targeted ...
Authors: Jeffrey Bax, Ian A. Cunningham, Aaron Fenster, Lori Gardi, Sule Karagulleoglu Kunduraci, Alla Reznik, David Tessier
Affiliation: Robarts Research Institute, Imaging Research Laboratories, Robarts Research Institute, Lakehead University
Abstract Preview: Purpose: Image-guided biopsy is critical for early diagnosis of prostate cancer (PCa), the most common cancer in men worldwide. While the prostate-specific PET (P-PET) system offers enhanced sensitivi...
Authors: Tina Ehtiati, Grace Jianan Gang, Limei Ma, Oleg Shekhtman, Visish M. Srinivasan
Affiliation: Siemens Medical Solutions USA, Inc., University of Pennsylvania
Abstract Preview: Purpose: Saccular aneurysms are the most common type of intracranial aneurysm and are typically treated by endovascular embolization. The procedure requires approximately orthogonal fluoroscopy images...
Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Chloe Doen Kim, Patricia E. Lindsay, Bern Norrlinger, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Queen's University, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To propose a method to check the consistency of VMAT delivery on linear accelerator (LINAC) with a commercial three-dimensional array device. The method is insensitive to the correction facto...
Authors: Beth M. Beadle, Adrian Celaya, Laurence Edward Court, David Fuentes, Anna Lee, Tze Yee Lim, Dragan Mirkovic, Amy Moreno, Raymond Mumme, Tucker J. Netherton, Callistus M. Nguyen, Jaganathan A Parameshwaran, Jack Phan, Carlos Sjogreen, Sara L. Thrower, Congjun Wang, He C. Wang, Xin Wang
Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, Stanford University, The University of Texas MD Anderson Cancer Center, MD Anderson Cancer Center, MD Anderson, Rice University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Quality assurance of target volumes from radiotherapy clinical trials is a labor and resource intensive task. The purpose of this work is to quantify the accuracy of a tool that automatically...
Authors: Ramesh Boggula, Lincoln Houghton
Affiliation: Karmanos Cancer Institute, Wayne State University
Abstract Preview: Purpose: To evaluate an approach that selectively applies adaptive re-planning only when needed to reduce clinical workload while maintaining treatment quality. Daily adaptive radiotherapy (ART) has t...
Authors: Edward D. Brandner, Weihua Fu, M. Saiful Huq, Ronald John Lalonde, Kiran Mehta, Hima Bindu Musunuru, Yongqian Zhang
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pittsburgh School of Medicine and UPMC Hillman CancerCenter
Abstract Preview: Purpose: Treatment of diffuse and extensive involvement of the skull by malignancy presents a difficult challenge for radiation therapy. This study reports preliminary experience of a modified volumet...
Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...
Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal
Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...
Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...
Authors: Matthew S Brown, Joshua Genender, John M. Hoffman, Gabriel Melendez-Corres, Muhammad W. Wahi-Anwar
Affiliation: David Geffen School of Medicine at UCLA, UCLA Department of Radiology
Abstract Preview: Purpose: Renal lesions are evaluated using scoring systems based on visual assessments and manual measurements. The purpose of this work is to develop a multi-agent system for automated anatomic landm...
Authors: Seifallah Emam, Gilberto Gonzalez, Anna E. Rodrigues
Affiliation: Duke University, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose:
To survey current therapeutic medical physics residents on 1) the accuracy with which residency programs were represented during interviews, 2) factors that most strongly impacted resident...
Authors: Sijuan Huang, Yongbao Li
Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China, Sun-Yat sen University Cancer Center
Abstract Preview: Purpose: Hematologic toxicity (HT) is one of the most prevalent treatment-related toxicities experienced by locally advanced cervical cancer (LACC) patients receiving radiotherapy (RT). This study aim...
Authors: Katelyn M. Atkins, Indrin J. Chetty, Elizabeth M. McKenzie, Taman Upadhaya, Samuel C. Zhang
Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center
Abstract Preview: Purpose:
We explored a multi-regional and multi-omics approach to extract CT-based radiomics and 3D dosiomics features to predict radiation pneumonitis (RP) in patients with locally advanced Non-Sm...
Authors: Shari Damast, Svetlana Kuznetsova, Christopher J. Tien
Affiliation: Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Current contour similarity evaluation approaches (Dice Similarity Coefficient, Mean Distance to Agreement) are limited to geometric agreement without assessment of ultimate dosimetric impact....
Authors: Jiayun Chen, Shengqi Chen, Yuan Tang, Zilin Wang, Guohua Wu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose:
To develop a novel no-reference image quality assessment (NRIQA) method for evaluating the effectiveness of image preprocessing in MRI-guided radiotherapy (MRIgRT), thereby enhancing clini...
Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval
Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...
Authors: Katherine Brown, Will Buchsbaum, Mylinh Dang, Joshua Dean, Sameer Faruquee, Gracie Huff, Claudia Maldonado, Gaby Min, David O'Neill, Gemily Wang, Poonam Yadav
Affiliation: Northwestern University, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine
Abstract Preview: Purpose:
To establish an abdominal imaging phantom that includes deformable organs including the stomach, duodenum, and pancreas. This phantom will be used in routine calibration of an MRI-LINAC sy...
Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo
Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...
Authors: Reza Farjam, Russell K Hales, Seth Jayawardane, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins School of Medicine
Abstract Preview: Purpose: This study presents a novel cost-effective customizable 3D-printed phantom developed for end-to-end treatment verification and image-quality assessment for thoracic applications.
Methods: ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Yufeng Cao, Arun Gopal, Kai Huang, Kai Wang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland Medical Center, University of Maryland, Baltimore
Abstract Preview: Purpose: The treatment of left-sided breast tumors poses significant concerns regarding the risk of radiation-induced damage to nearby organs, particularly the heart. In clinical practice, breath-hold...
Authors: Christopher L. Deufel, Suman Gautam, William Y. Song
Affiliation: Virginia Commonwealth University, Mayo Clinic
Abstract Preview: Purpose: Direction modulated brachytherapy creates anisotropic dose distribution from an isotropic source. This study aims to develop a truncated conditional value at risk optimization algorithm for D...
Authors: Dale W. Litzenberg, Ikechi S Ozoemelam, Rowan Paplanus, Michael Pillainayagam, Donald A. Roberts
Affiliation: University of Michigan, Oregon Health & Science University
Abstract Preview: Purpose: Clinical linear accelerators use dual foil scattering systems designed to achieve large uniform fields (up to 25Ă25cmÂČ), which can reduce beam fluence by up to 93% compared to the unmodified ...
Authors: James Robert Castle, Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: We propose a novel methodology for lattice deployment in spatially fractionated radiotherapy (SFRT), using principal component analysis (PCA) to improve sphere packing within the tumor. Impro...
Authors: Savannah Decker, Grace Gwe-Ya Kim, Laura Padilla
Affiliation: UC San Diego, University of California San Diego
Abstract Preview: Purpose: The success of surface-guided deep-inspiration breath-hold (SG-DIBH) treatments depends on accurate identification of suitable candidates. Sub-optimal patient selection can result in prolonge...
Authors: Julien Bancheri, Jan P. Seuntjens
Affiliation: Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre & University of Toronto
Abstract Preview: Purpose: To obtain an analytical expression for the charge collection efficiency of parallel-plate ionization chambers in high dose-per-pulse (DPP) beams that takes into account the square pulse time ...
Authors: Courtney R. Buckey, Jay W. Burmeister, Minsong Cao, Grace Chang, Yu Kuang, Yixiang Liao, Yi Rong, Dandan Zheng
Affiliation: Mayo Clinic, Mayo Clinic Arizona, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, Medical Physics Program, University of Nevada, Rush University Medical Center, University of Rochester
Abstract Preview: Purpose: Investigate the adequacy of training for therapeutic medical physics residents in select special procedures.
Methods: After a review of existing literature, a multi-institutional group dev...
Authors: Christopher Colyer, Leon F Dunn, Jonathan Dunning, Simon Goodall, Andy Schofield
Affiliation: GenesisCare
Abstract Preview: Purpose: Modern radiotherapy is characterized by complex treatment plans utilizing dynamic MLCs, gantry positions and recently, collimator rotations. The purpose of this work was to compare the plan c...
Authors: Thomas Gee, Sofia Michopoulou, Amit Nautiyal
Affiliation: University Hospital Southampton
Abstract Preview: Purpose: Dosimetry software that is accessible to departments offers new opportunities to improve patient-specific dosimetry. Prior to clinical decision-making, it is essential to validate dosimetry s...
Authors: Zhenzhen Dai, Anthony J. Doemer, Ryan Hall, Kenneth Levin, Bing Luo, Benjamin Movsas, Karen C. Snyder, Kundan S Thind, Eleanor Walker
Affiliation: Henry Ford Health, HFHS
Abstract Preview: Purpose: To investigate the feasibility of a predictive tool for efficient allocation of hypofractionated whole-breast irradiation patients between Varian Truebeam and Ethos systems.
Methods: A ful...
Authors: Ming Su, Yuenan Nancy Wang
Affiliation: Northeastern University, Hartford Healthcare
Abstract Preview: Purpose: High Z elements such as lead are often used to protect critical structures in clinical radiotherapy. Nanoparticles have different properties than bulk materials. We proposed a polymer matrix ...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...
Authors: Ivan L. Cordrey, Dharmin D. Desai
Affiliation: Cumberland Medical Center - Cancer Center, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: For larger PTVs, VMAT optimizations performed within Eclipse often generate SRS plans with widely scattered hotspots distributed around the inner edge of the PTV â the âring of fire.â This pr...
Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...
Authors: Dequan Chen, Jason Michael Holmes, Tianming Liu, Wei Liu, Zhengliang Liu, Jiajian Shen, Peilong Wang
Affiliation: Department of Radiology, Mayo Clinic, Department of Radiation Oncology, Mayo Clinic, School of Computing, University of Georgia
Abstract Preview: Purpose:
We present a study to evaluate the performance of large language models (LLMs) in answering radiation oncology physics questions, focusing on the recently released models.
Methods:
A...
Authors: Wesley E. Bolch, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Lazaro Fuentes Alfonso, Shreya P. Pathak, Julia D. Withrow
Affiliation: University of Florida
Abstract Preview: Purpose: To develop tetrahedral mesh-based tissue models within the breasts of the International Commission on Radiological Protection (ICRP) adult female mesh-type reference computational phantom (AF...
Authors: Benjamin W. Maloney, Ashley E. Rubinstein, Colin Schaeffer, Justin Yu
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Radiography AEC systems ensure correctly exposed images for varied kVp and patient thicknesses. The specific kVp and PMMA thicknesses selected for testing AEC tracking may affect passing rate...
Authors: Yanique N. Dunn, Marissa Joyce Vaccarelli
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: The U.S. Nuclear Regulatory Commission (USNRC) Event Notification Reports provide detailed information on nuclear-related events, including medical and non-medical incidents. This study evalu...
Authors: Liu Hong, Wen C. Hsi, Faraz Kalantari, Romy Megahed, Ganesh Narayanasamy, Maida Ranjbar, Pouya Sabouri, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: Quantitative apparent diffusion coefficients (ADC) in diffusion-weighted MRI (dMRI) reflect water diffusivity and thus provide tissue cellular density information. Functional diffusion mappin...
Authors: Ila Farhang, Ryan D. Foster, Devin Heitz, Jordan B Lunsford, Ashkan Shafiee
Affiliation: Atrium Health Wake Forest Baptist, Atrium Health/LCI Cabarrus
Abstract Preview: Purpose: American Association of Physicists in Medicine (AAPM) Task Group (TG) -51 is a widely utilized protocol for the absolute calibration of linear accelerators. The purpose of this project was fo...
Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...
Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...
Authors: Deshan Yang, Zhendong Zhang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose:
The evaluation of deformable image registration (DIR) algorithms is crucial for improving accuracy and clinical adoption. However, reliable benchmarks, especially for inter-modality regist...
Authors: Neil A. Kirby, Parker New, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz
Affiliation: UT Health San Antonio
Abstract Preview: Purpose: To simplify the traditional method of patient-specific skin collimation and improve the precision of electron radiotherapy treatment with a new surface conforming collimation system.
Metho...
Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Walaa Abdelfadeel, Reagan Thomas Dugan, Tiffany Kinsey, Cameron Kofler, Zheng Feng Lu, Ingrid S. Reiser, Gregory Stacy, Sara Wallace
Affiliation: University of Chicago Medicine, University of Chicago
Abstract Preview: Purpose: To develop an accurate, vendor-neutral method for estimating geometric magnification at the plane of the hip joint on standing anterior-posterior (AP) radiographs for digital templating of to...
Authors: Weigang Hu
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: The purpose of this study is to introduce a VQVAE-based framework that addresses the limitations of conventional dose prediction methods, which rely on fixed deep learning models that produce...
Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl
Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...
Authors: Kostas Danniidis, Agelos Kratimenos, Yufu Wang, Timothy C. Zhu, Yifeng Zhu
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: This study aims to develop software and algorithms utilizing artificial intelligence (AI) to seamlessly create 3D patient postures during Total Skin Electron Therapy (TSET). The resulting mes...
Authors: ISAAC Amoah, Jackie Austin, Charlotte Block, Kaylee Brilz, Dylan Bui, Andrew E. Ekpenyong, Jayce Hughes, Pralhad Itani, Natasha Ratnapradipa, Sara Strom, Jacob Woolf
Affiliation: Creighton University
Abstract Preview: Purpose:
Glioblastoma (GBM) is the most common and aggressive primary brain tumor in adults, with a median survival of approximately 15 months despite the current standard of care, which includes s...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...
Authors: Giovanni Iacca, Gloria Miori, Laura Orsingher, Daniele Ravanelli, Annalisa Trianni
Affiliation: Department of Information Engineering and Computer Science, University of Trento, Medical Physics Department, S.Chiara Hospital, APSS
Abstract Preview: Purpose: This study aims to leverage artificial intelligence (AI) to predict and identify performance degradation in Digital Radiography (DR) systems, enabling proactive maintenance and minimizing cli...
Authors: Shanli Ding, Osama R. Mawlawi, Tinsu Pan
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Reliable detection of anomalies in Gamma Camera/SPECT flood images is vital for quality assurance (QA). Traditional methods relying on numerical thresholds and manual inspections often mis...
Authors: Sean P. Devan, Cory S. Knill, Charles K. Matrosic, Zheng Zhang
Affiliation: University of Michigan
Abstract Preview: Purpose: Physicists troubleshooting machine issues during patient treatments often face high-pressure situations, balancing error codes, resource constraints, and time-sensitive decisions. To streamli...
Authors: Larry A. DeWerd, Sean Jollota, Karen Rex Pius Vincent
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Absolute measurements, often used to establish primary standards, offer lower measurement uncertainty. For 192Ir high-dose-rate (HDR) brachytherapy, the interim primary standard for air-kerma...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...
Authors: Yunxiang Li, Xinlong Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Acquiring high-resolution (HR) proton density (PD) images is time-consuming, while lower-resolution (LR) PD scans are faster but can lack sufficient details. We propose CycleHR, a T2-contrast...
Authors: Michael Caulfield, Ye Chen, Yoshihiro Ishi, Yasutoshi Kuriyama, Taeko Matsuura, Naoki Miyamoto, Taichi Murakami, Tomonori Uesugi, Kohei Yokokawa
Affiliation: Hokkaido University, Kyoto University, University of Alberta
Abstract Preview: Purpose: Protoacoustics has the potential for real-time and direct imaging of the Bragg peak. This study investigated the accuracy of the Bragg peak imaging based on the water phantom experiment at a ...
Authors: Emi Ai Eastman, Chao Guo, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
Smoking is one of the risk factors for coronary artery disease. It is desirable to estimate the coronary artery calcification (CAC), a key biomarker for atherosclerosis and cardiovascular ...
Authors: Amir Abdollahi, Oliver JĂ€kel, Maxmillian Knoll, Rakshana Murugan, Adithya Raman, Patrick Salome
Affiliation: UKHD & DKFZ, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), German Cancer Research Centre(DKFZ), DKFZ, MGH
Abstract Preview: Purpose:
Missing MRI sequences, due to technical issues in data handling or clinical constraints like contrast agent intolerance, limit the use of medical imaging datasets in computational analysis...
Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Bangho Shin, Yitian Wang
Affiliation: University of Florida
Abstract Preview: Purpose: The skeleton plays a critical role in dosimetry, containing red bone marrow (RBM) and bone endosteum (BE), which are closely linked to radiation-induced leukemia and bone cancer. While severa...
Authors: Adayabalam Balajee, Elijah Berberette, Maria Escalona, Dray Gentry, Chester R. Ramsey, Terri Ryan
Affiliation: ORAU, Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose:
Dicentric chromosomes, characterized by two centromeres on a single chromosome, are key biomarkers in biological dosimetry for quantifying ionizing radiation exposure. However, manual dete...
Authors: Shae Gans, Carri K. Glide-Hurst, Mark Pankuch, Chase Ruff, Niek Schreuder, Nicholas R. Summerfield, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center, Leo Cancer Care
Abstract Preview: Purpose: Novel upright patient positioners coupled with diagnostic-quality vertical CT at treatment isocenter introduce a significant opportunity for improved image-guided particle therapy. Treating p...
Authors: Amir Abdollahi, Celine Karle, Michele M. Kim, Constantinos Koumenis, Andrea Mairani, Erato Stylianou Markidou
Affiliation: Heidelberg Ion-Beam Therapy Center - Department of Radiation Oncology, German Cancer Research Centre(DKFZ), University of Pennsylvania, Physics Dep. University of Cyprus
Abstract Preview: Purpose: The aim is to compare FLASH dose-rate RT generated with protons and carbon (HIT) and compare to protons (UPenn) to provide evidence for equipotency of FLASH vs. standard RT to tumor growth co...
Authors: Anzi Zhao
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: This study investigates the utility of Dual-Energy Computed Tomography (DECT) material decomposition in resolving Magnetic Resonance Imaging (MRI) safety concerns for patients with unidentifi...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Himanshu Joshi, Tian Liu, Deborah C Marshall, Joseph Shelton, Jing Wang, Xiaofeng Yang, Emi Yoshida, Boran Zhou
Affiliation: Department of Radiation Oncology, Baylor College of Medicine, Icahn School of Medicine at Mount Sinai, Emory University, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, University of California, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Radiation-induced long-term toxicities, such as vaginal stenosis, significantly impact the quality of life for patients undergoing pelvic radiotherapy (RT) for gynecologic (GYN) malignancies....
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Richard L.J. Qiu, Mojtaba Safari, Shansong Wang, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: MRI offers excellent soft tissue contrast for diagnosis and treatment but suffers from long acquisition times, causing patient discomfort and motion artifacts. To accelerate MRI, supervised d...
Authors: Meixu Chen, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center
Abstract Preview: Purpose: Cancer treatment outcome prediction plays a pivotal role in guiding therapeutic decisions and optimizing patient care. Traditionally, binary prediction models have been widely used for risk s...
Authors: Cem Altunbas, Farhang Bayat
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose:
Low dose imaging and scatter rejection hardware in CBCT reduces X-ray fluence incident on the imager, increasing noise, causing photon starvation artifacts in CBCT images. In this work, we...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou Peopleâs Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleÊŒs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Alexandra Christensen, Timothy J. Hall, Ivan M. Rosado-Mendez
Affiliation: University of Wisconsin, Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: Quantitative ultrasound techniques based on the statistical analysis of speckle are currently being deployed commercially and clinically as sources of biomarkers associated with tissue micros...
Authors: Zachery Colbert, Matthew Foote, Michael Huo, Mark Pinkham, Prabhakar Ramachandran, Mihir Shanker
Affiliation: Radiation Oncology, Princess Alexandra Hospital, Ipswich Road, Princess Alexandra Hospital
Abstract Preview: Purpose: The study aimed to develop and implement deep learning-based autosegmentation models for the autosegmentation of four key tumor types: brain metastasis, pituitary adenoma, vestibular schwanno...
Authors: Josephine Chen, CheukKai Becket Hui, Yildirim D. Mutaf
Affiliation: Kaiser Permanente
Abstract Preview: Purpose:
To demonstrate the effectiveness of a target clustering program in generating cluster configurations and isocenter placements for multiple brain lesions in SRS treatment planning, with the...
Authors: Harsh Arya, Yan Chang, Yujie Chi, Varghese Anto Chirayath, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: In targeted alpha therapy (TAT), absorbed dose rates can vary significantly spatially and temporally, impacting therapeutic efficacy as well as carcinogenic potential. This study reports the ...
Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...
Authors: Jeremy Christophel, Zhihua Qi
Affiliation: Henry Ford Health
Abstract Preview: Purpose: To demonstrate a method to compare DICOM metadata from clinical scanners with institutional protocols as validation that clinical use matches the master protocol.
Methods: DICOM metadata i...
Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...
Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Curation remains a significant barrier to the use of âbig dataâ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...
Authors: Jingyun Chen, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology
Abstract Preview: Purpose: To develop and evaluate the Scale-attention network (SANet) for automated pancreas segmentation on MR images.
Methods: To develop SANet, we extended the classic U-Net design with a dynamic...
Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...
Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...
Authors: John Bennet, Indrin J. Chetty, Tai H. Dou
Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center
Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...
Authors: Peter Balogh, Wesley E. Bolch, Mir Md Nasim Hossain, Nien-Wen Hu, Walter Murfee, Wyatt Smither, Julia D. Withrow
Affiliation: New Jersey Institute of Technology, University of Florida
Abstract Preview: Purpose: To develop 3D computational, tissue-representative models incorporating physiologically relevant microvascular network patterns for calculating local alpha particle and electron dosimetry eff...
Authors: Olivier Blasi, Eric Cameron, Brad K. Lofton
Affiliation: CAMP, Colorado Assn in Medical Phys (CAMP)
Abstract Preview: Purpose:
Magnetic Resonance (MR) imaging obtained from external centers for radiation therapy (RT) planning can suffer from suboptimal protocols and geometric distortions. These issues can require ...
Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine
Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...
Authors: Hao Gao, Xue Hong, Harold Li, Yuting Lin, Jufri Setianegara, Xin Tong, Chao Wang, Weijie Zhang, Ya-Nan Zhu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high radiation doses to specific tumor regions (vertices) while sparing surroun...
Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,
Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...
Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, Michael Leyva, Alejandro Rene Llanes Lopez, Carlos M. Rivera, Ranjini P. Tolakanahalli
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose: Accurate treatment time calculation is a critical component of superficial radiotherapy (SRT), particularly for the SRT-100 Vision, where dose delivery depends on applicator geometry, treatme...
Authors: Juan-Francisco Calvo-Ortega, Andrew Cousins, Ashley Cullen, Andrew Dipulia, Peter B. Greer, Seng Boh Gary Lim, Shih-Chi Lin, D. Michael Lovelock, Conor McGarry, Victoria Robinson, Cameron Stanton, Baozhou Sun, Ching-Ling Teng, Gemma Warner, Benjamin J. Zwan
Affiliation: Northern Ireland Cancer Centre, Baylor College of Medicine, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Christchurch Hospital, Northwell, Central Coast Cancer Centre, Calvary Mater Hospital, Hospital Quironsalud Barcelona, Icahn School of Medicine at Mount Sinai, Chris O'Brien Lifehouse, University of Newcastle
Abstract Preview: Purpose: This multi-institution Electronic Silicon-based Remote Survey of Small-field Output (ESPRESSO) study aims to develop the remote audit process to evaluate the safety of single-isocenter multi-...
Authors: Anna Becker, Tomislav Bokulic, Mauro Carrara, Krzysztof Chelminski, Larry A. DeWerd, Alexis Dimitriadis, Benjamin Kellogg, Malcolm R. McEwen, Zakithi L.M Msimang, Mark J. Rivard, Thorsten Sander, Thorsten Schneider, Jamema Swamidas, Egor Titovich, Paula Toroi, Carlos E. de Almeida, Jacco de Pooter, Liset de la Fuente Rosales, Deborah G. van der Merwe
Affiliation: Radiation and Nuclear Safety Authority, University of Zagreb, National Physical Laboratory, IAEA, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Rio de Janeiro State University, Dosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Physikalisch-Technische Bundesanstalt, National Metrology Institute, University of the Witwatersrand, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, National Research Council, Warren Alpert Medical School of Brown University
Abstract Preview: Purpose: The recently published IAEA-TRS-492 international code of practice (CoP) aims at improving traceability, accuracy, and consistency in Brachytherapy Dosimetry. To assess current approaches to ...
Authors: Carlo Greco, Joep Stroom, Sandra Vieira
Affiliation: Champalimaud Center for the Unknown
Abstract Preview: Purpose: RTP safety margins are generally based on geometrical uncertainties alone and not directly on clinical outcome. Here we use clinical dose-constraint data to generate dosimetric margins for OA...
Authors: James R Duncan, Nikhat Fatima Mansoori, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Collimation during fluoroscopically-guided interventions (FGIs) can not only reduce radiation exposure to patients and personnel but also improve image quality. Nonetheless, there are concern...
Authors: Ashley Cetnar, Lin Ding, Jeffrey E. Woollard
Affiliation: The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: A cohort of middle school and high school science teachers were selected to learn about physics in medicine, develop lesson plans for their students, participate in a Physics in Medicine fiel...
Authors: Lavsen Dahal, Francesco Ria, Ehsan Samei, Justin B. Solomon, Liesbeth Vancoillie, Yakun Zhang
Affiliation: Duke University, Carilion Clinic, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Clinical diagnostic task-based optimization of CT procedures require precise and organ-specific assessments. This study investigates inter-organ noise variability to highlight the limitations...
Authors: Santosh K. Agarwalla, Nrusingh C. Biswal, Shree C, Harikrishnan Suresh Kumar, Jajati K. Nayak, Prema P., Sarath K S, Tamil Selvan S, Hem D. Shukla
Affiliation: Variable Energy Cyclotron Centre, Department of Physics, Fakir Mohan University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Sciences, Amrita Vishwa Vidyapeetham
Abstract Preview: Purpose: The rapid oxygen depletion in tissues during irradiation is the most accepted mechanism of the FLASH effect. However, the Normal Tissue Complication Probability (NTCP) and Tumor Control Proba...
Authors: Yile Fang, Leslie Lamb, Nathaniel David Mercaldo, Kai Yang
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantitatively evaluate power-law exponent ÎČ as a potential image-based breast cancer risk factor.
Methods: Two groups of breast cancer screening cohorts (target vs. control, 20 sub...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Zhitao Dai
Affiliation: Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital
Abstract Preview: Purpose: To investigate the accuracy of 3D printed individualized vaginal template assisted pre-planning in the interstitial implantation of cervical cancer, to examine the advantages when compared wi...
Authors: Ashley Cetnar
Affiliation: The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: Undergraduate students are eager to learn more about potential career opportunities. While many physics majors are aware of research opportunities within the physics department, students may ...
Authors: Hideaki Hirashima, Haruo Inokuchi, Nobutaka Mukumoto, Naruki Murahashi, Mitsuhiro Nakamura, Megumi Nakao, Keiko Shibuya, Linna Zhang
Affiliation: Kyoto University, Osaka Metropolitan University
Abstract Preview: Purpose:
To transform the quality of 2D cine MR images acquired during online adaptive MR-guided radiotherapy (OA-MRgRT) by utilizing a conditional diffusion model to achieve image quality comparab...
Authors: Sophie Bockel, Eric Deutsch, Frederic Dhermain, Ibrahima Diallo, Anh Thu Le, Elaine Limkin, Pauline Maury, Charlotte Robert, Killian Sambourg, Camilla Satragno, Cristina Veres, François de Kermenguy
Affiliation: Gustave Roussy, Département de radiothérapie, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique
Abstract Preview: Purpose:
To study the correlation between the dose to circulating lymphocytes as evaluated by the LymphoDose framework and the incidence of severe radiation-induced lymphopenia (sRIL) in patients t...
Authors: Mylinh Dang, Laila A Gharzai, Xinlei Mi, Poonam Yadav
Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine
Abstract Preview: Purpose: Delineation of organs at risk (OAR) in the head/neck region requires substantial physician time. Many artificial intelligence (AI) based auto-contouring software are commercially available. T...
Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...
Authors: Zachary M. Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: High spatial resolution in pin ridge filter (pRF)-based proton planning may be constrained by the 1mm dose grid resolution in commercial treatment planning systems. This study investigates th...
Authors: Sarah A. Ashmeg, Travis James McCaw, Joseph Shields, Matthew Spector, Christopher Tyerech, Christopher T Wilke
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: Patients with oral cavity cancer often undergo surgical extirpation prior to radiation, and surgical implants are utilized to reconstruct the resulting defect. This study dosimetrically evalu...
Authors: Xinhua Li, Vu Nguyen, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Assessing iodine concentration in liver lesions is essential for evaluating contrast enhancement in multi-phase liver CT and for accurate disease diagnosis. This study aims to evaluate the as...
Authors: Rosa Maria CibriĂĄn Ortiz de Anda, Altea C Esteve, Carlos M Galindo-GonzĂĄlez, Carmen C GarcĂa, Amparo Gonzalez-Sanchis, Jose C Gordo-Partearroyo, Emilio Soria-Olivas, Javier Vijande
Affiliation: IFIC-UV, Valencia University, Hospital General Universitario
Abstract Preview: Purpose: To determine how skin microcirculation is affected by the two hypo-fractionated radiotherapy protocols in breast cancer patients using Laser Doppler Imaging, a non-invasive method for assessi...
Authors: Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Nancy Y Lee, Anyi Li, Jung Hun Oh, Teeradon Treechairusame, Pengpeng Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To automatically monitor weekly anatomical changes of parotid glands during adaptive radiotherapy of head and neck cancers, systematically assess the relationship between parotid gland shrink...
Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson
Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Daniel A. Alexander, Anish Butala, Anthony Austin Kassaee, Neil Malhotra, Ian Messing, Gabrielle W Peters, Ryan M. Scheuermann
Affiliation: Department of Radiation Oncology and Applied Sciences, University of Pennsylvania
Abstract Preview: Purpose: Stereotactic Body Radiation Therapy (SBRT) for spinal metastases uses CBCT-based localization and highly conformal treatment delivery to increase the biologically equivalent dose to the targe...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...
Authors: Justus Adamson, Wesley Andrew Cunningham, Caleb Logan Smith
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: Radiation induced bowel toxicity is a persistent issue for abdominal Stereotactic Body Radiation Therapy (SBRT). Remote magnetic navigation systems (RMNS) have been developed for use in magne...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Shahed Badiyan, Tsuicheng D. Chiu, Viktor M. Iakovenko, Steve Jiang, Christopher Kabat, Mu-Han Lin, Roberto Pellegrini, Arnold Pompos, Edoardo Salmeri, David Sher, Sruthi Sivabhaskar, Justin D. Visak
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Global Clinical Science, Elekta AB, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Adaptive treatment planning requires robust strategies to enable streamlined on-couch processes, creating a significant barrier for planners transitioning from conventional to adaptive planni...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose:
Pancreatic cancer poses therapeutic challenges due to the proximity of critical organs, requiring precise radiotherapy. Magnetic resonance (MR)-guided linear accelerators provide daily ima...
Authors: Nawal Alqethami, Felix Ginzinger, Prasannakumar Palaniappan, Marco Riboldi, Philipp Steininger, Wentao Xie
Affiliation: Research & Development, medPhoton GmbH, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich)
Abstract Preview: Purpose:
This study evaluates the image quality of Dual-Energy (DE) X-ray imaging for lung tumor tracking across various sizes and protocols, comparing its imaging dose to Single-Energy (SE) imagin...
Authors: Izabella L. Barreto, Aroon Pressram
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Our clinical dual energy CT (DECT) head protocol reconstructs iodine-suppressed virtual non-contrast (VNC) images using the vendor-recommended slope for material discrimination. However, this...
Authors: Derek Matthew Garcia, Mallory Glenn, Stephen F. Kry, Ruitao Lin, Dennis S. Mackin, Tucker J. Netherton
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texasâ MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: This study aims to investigate the feasibility of implementing clinically relevant quality metrics for evaluating IROC SRS phantom plans, including conformity index (CI) and homogeneity index...
Authors: Zachary Carr, Katie W. Hulme, Zaiyang Long, Nathan A. Quails, Ashley Tao
Affiliation: Gundersen Health System, Ohio State University Wexner Medical Center, Mayo Clinic, Ohio State Wexner Medical Center, The Cleveland Clinic
Abstract Preview: Purpose: Meaningful interpretation of deviation index (DI) in clinical practice relies on appropriately set target exposure indices (EIT). EIT values for a given exam-view can be derived from the medi...
Authors: David Alejandro Collazos Burbano, Antonio Adilton Oliveira Carneiro, Paul L. Carson, Jose Eduardo Freire, Theo Zeferino Pavan, Joao Henrique Uliana, Nicholas Zufelato
Affiliation: University of SĂŁo Paulo, University of Michigan, University of Sao Paulo
Abstract Preview: Purpose: Develop a theranostic platform that integrates magnetic hyperthermia (MH), ultrasound, and magnetic nanoparticles (MNPs) to improve diagnosis, treatment, and monitoring of hyperthermia proced...
Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Francia Romero, Niara Rowe, Roland Teboh
Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center
Abstract Preview: Purpose: Daily use and reliance on the auto registration feature requires a performance check. Clinical application of auto registration is performed without a selected region of interest (ROI), requi...
Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington
Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging is a powerful tool for localizing entrance and exit dose during radiotherapy treatment. The current implementation uses an intensified-CMOS (iCMOS) camera allowing for high-...
Authors: Yuemeng Feng, Hamid Sabet
Affiliation: Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: We propose a novel brain-dedicated PET system comprising elliptical cylinder with a neck cut-out, supplemented by front and back panels to improve sensitivity and line-of-response sampling. T...
Authors: Sven Ferguson, S. Murty Goddu, Ana Heermann, Taeho Kim, Nels C. Knutson, Hugh HC Lee, Shanti Marasini, Timothy Mitchell, Seungjong Oh, Kevin Renick
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: In the Gamma Knife stereotactic radiosurgery (GK-SRS), the delineation of organs-at-risks (OARs) was not fully automated. Due to the cumbersome nature of manual OAR contouring, dose evaluatio...
Authors: Jon Hansen
Affiliation: Washington University in St Louis
Abstract Preview: Purpose: Commercially available auto-segmentation software was utilized to generate institution-specific optimization structures for spine stereotactic body radiation therapy (SBRT). Implementation of...
Authors: Leigh A. Conroy, Thomas G Purdie, Christy Wong
Affiliation: Department of Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To develop a novel machine learning (ML) algorithm to evaluate and rank breast radiation therapy (RT) treatment plans based on treatment complexity for prioritization in multidisciplinary pee...
Authors: Ergun E. Ahunbay, Abdul Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Online adaptive replanning is often necessary in Intensity Modulated Proton Therapy (IMPT) due to the sensitivity of proton dose distributions to daily anatomical changes. A rapid, automated ...
Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...
Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi
Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals
Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...
Authors: David L. Barbee, David Byun, Matt Long, Jose R. Teruel Antolin, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose:
Online adaptive MR-Linac therapy requires contour adaptation, often adding 20 minutes to treatment time and reducing machine throughput. This study introduces a fully automated MR contour ...
Authors: Muhammad Ramish Ashraf, Dixin Chen, Lloyd Emmanuel Kamole Ghomsi, Edward Elliot Graves, Billy W Loo, Stavros Melemenidis, Joseph B. Schulz, Lawrie Skinner
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Precise beam collimation is essential in preclinical radiotherapy studies to ensure accurate dose delivery. Manual design and fabrication of organ-specific collimators usually consist of mult...
Authors: Kyle J. Wang, Yading Yuan
Affiliation: Bergen County Technical High School, Columbia University Irving Medical Center, Department of Radiation Oncology
Abstract Preview: Purpose: Genotoxic cancer therapies inevitably damage normal cells, particularly circulating hematopoietic cells, posting a risk for therapy-induced leukemia. This study aims to develop an automated i...
Authors: Maria Jose Almada, Bruno Forti, Andres Lima, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
To automate the planning of radiotherapy treatments for bone metastases using a script in the ECLIPSE planning system version 15.6 with a graphical interface.
Methods:
A script was d...
Authors: Chase Cochran, Shane McCarthy, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Manually generating intraocular stereotactic radiosurgery (SRS) plans involves significant challenges, including lengthy planning times and inter-planner variability. Knowledge-based SRS plan...
Authors: Hongyi Jiang, Fang-Fang Yin
Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Imaging moving tissues using PET-CT can be difficult. Separating signal into phases during construction reduces signal count and increases influence of noise. Algorithms that use signal fr...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...
Authors: Michael Ashenafi, Mario Ramos Gallardo, Amy Herman, Sean M. Tanny
Affiliation: Department of Radiation Oncology, University of Rochester
Abstract Preview: Purpose: Updates to the Varian Eclipse Treatment Planning System (TPS) have introduced new objects to replace pre-existing Clinical Protocols to aide clinicians in plan quality assessment. We have cre...
Authors: Steve Braunstein, Angela Jakary, Hui Lin, Bo Liu, Janine Lupo, Tiffany Ngan, Ke Sheng, Nate Tran
Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Radiology and Biomedical Imaging, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Current RT clinical target volumes (CTVs) for Glioblastoma (GBM) employ 2cm isotropic expansions of gross tumor volumes. However, studies showed patients still experience progression beyond t...
Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos
Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen
Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...
Authors: Xianjin Dai, PhD, Zhuoran Jiang, Lei Ren, Lei Xing, Zhendong Zhang
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, Stanford University, Duke University, Stanford University
Abstract Preview: Purpose: Unsupervised deep learning has shown great promise in deformable image registration (DIR). These methods update model weights to optimize image similarity without necessitating ground truth d...
Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: Tumor hypoxiaâa state of reduced oxygen supplyâis well known to affect treatment response, particularly in radiotherapy and chemotherapy. Oxygen-enhanced magnetic resonance imaging (OE-MRI) u...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Md Mainul Abrar, Harsh Arya, Yujie Chi, Yijing Liu, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, The University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Understanding the biological effects of alpha radiation at varying dose rates and energies is essential for advancing therapeutic strategies. This study demonstrates the capabilities of an in...
Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania
Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...
Authors: David J. Gladstone, P. Jack Hoopes, David I Hunter, Brian W Pogue, Jacob Pierce Sunnerberg, Armin Tavakkoli
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Geisel School of Medicine, Dartmouth College
Abstract Preview: Purpose: The FLASH effect, characterized by normal tissue sparing under ultra-high dose rate (UHDR) radiation delivery, remains mechanistically unclear. This study investigated the relationship betwee...
Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou
Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, Peopleâs Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial Peopleâs Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital
Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...
Authors: Rex A. Cardan, Carlos E. Cardenas, Quan Chen, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Yi Rong, Dennis N. Stanley, Natalie N. Viscariello, Libing Zhu
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Manual verification of organs-at-risk(OARs) delineations is a critical yet time-intensive process, often susceptible to unintentional oversights. To assist the reviewing process, a population...
Authors: Cristel Baiu, Laura Castaneda Martinez, Ivan M. Rosado-Mendez
Affiliation: University of Wisconsin, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: 2D matrix array transducers (2DMAT) are advancing volumetric ultrasound due to their ability to provide more isotropic 3D resolution, fast volumetric imaging, and highly customizable focusing...
Authors: Jorge Naoki Dominguez Kondo, Qihui Lyu
Affiliation: University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Targeted alpha therapy (TAT) has emerged as a highly potent therapeutic method in oncology, but its development is limited by the lack of imaging methods to quantify its dosimetry. Convent...
Authors: Giacomo Avesani, Matthew D Blackledge, Silvia Bottazzi, Alison Tree, Nina Tunariu
Affiliation: Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Institute of Cancer Research, The Royal Marsden NHS Foundation Trust
Abstract Preview: Purpose: To evaluate changes in median apparent diffusion coefficient (ADC) within metastatic oligoprogressing lesions from prostate cancer treated with stereotactic body radiotherapy (SBRT) and compa...
Authors: Julien Bancheri, Chau Giang Bui, Christopher M Lund, Morgan J Maher, Jamiel Nasser, Amy Parent, Monica Serban, Jan P. Seuntjens, Jason Z Yuan
Affiliation: University of Toronto, Medical Physics Unit, McGill University, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre & University of Toronto
Abstract Preview: Purpose: Proton therapy (PT) has demonstrated greater precision and superior healthy tissue sparing compared to photon radiotherapy for various sites; however, PT systems are expensive, which limits g...
Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center
Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...
Authors: Wilfred R Furtado, Gary Y. Ge, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: The United Kingdom and several other countries already have well-established diagnostic reference levels (DRLs) for gastrointestinal fluoroscopic procedures, whereas the United States does no...
Authors: Peter Balter, Kristy K. Brock, Clifton David Fuller, Tze Yee Lim, James Long, Brigid A. McDonald, Androniki Mitrou, Andrew J. Schaefer, Stina Svensson
Affiliation: The University of Texas MD Anderson Cancer Center, RaySearch Laboratories, Rice University, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: CBCT-based accumulated dose can provide up-to-date dose information on responding anatomy. To optimize resources, it is necessary to determine how many scans provide adequate information for ...
Authors: Casey E. Bojechko, Lance C Moore
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: EPID images collected during treatment can serve as an in-vivo error detection mechanism. Previous works have shown that comparing in-vivo EPID images to AI-predicted EPID images for IMRT pla...
Authors: Shaheen Dewji, Emmanuel Mate-Kole, Sergio F Ruiz, Chris C. Wang
Affiliation: Georgia Institute of Technology, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: Extravasations are clinical events when a substance is administered intravenously and the fluid starts to leak into surrounding tissue instead of the target vessel. In the case of radiopharma...
Authors: Evan Calabrese, Hangjie Ji, Kyle J. Lafata, Casey Y. Lee, Eugene Vaios, Chunhao Wang, Lana Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University, North Carolina State University
Abstract Preview: Purpose: To develop a biologically guided deep learning (DL) model for predicting brain metastasis(BM) local control outcomes following stereotactic radiosurgery (SRS). By integrating pre-SRS MR image...
Authors: Liyuan Chen, Steve Jiang, Chenyang Shen
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center
Abstract Preview: Purpose: Delays in radiation therapy (RT) initiation caused by conventional CT simulation processes can hinder timely treatment delivery and patient outcomes. This study proposes a Virtual Treatment S...
Authors: Michael Kudla, Stephanie Merkl
Affiliation: BC Cancer - Kelowna
Abstract Preview: Purpose: 3D modeling for 3D printed GYN high dose rate (HDR) brachytherapy templates can be a time-consuming, error-prone process. To simplify the creation these templates, a software application has ...
Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...
Authors: Taylor A Beal, Kari J. Brewer Savannah, Kristy K. Brock, Alejandro Contreras, Natalie W Fowlkes, Megan Kalambo, Gregory P Reece, Erin P Snoddy, Tien T Tang
Affiliation: The University of Texas MD Anderson Cancer Center, Baylor College of Medicine
Abstract Preview: Purpose: Current anatomical and surgical research does not adequately detail the breast fascial systemâs ligaments and connective tissues. Most available information stems from cadaver dissections, wh...
Authors: Yingxuan Chen, Jun Li, Alexis N. Webb
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Cone-beam computed-tomography (CBCT) is widely used for image-guided therapy. Cumulative dose from repeated CBCT might be a concern. This study aims to measure and compare the CBCT dose for c...
Authors: Martha J. Malin, Matthew Schelin
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.
Authors: Sam Beddar, Jason Michael Holmes, Daniel G. Robertson, James J. Sohn, Ethan D. Stolen
Affiliation: Department of Radiation Oncology, Mayo Clinic, MD Anderson Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago
Abstract Preview: Purpose: Camera-based scintillation dosimetry incorporating large volumes have shown promise for fast and comprehensive evaluation of external beam treatment fields. While some efforts have been made ...
Authors: Ashok Bhandari, Kurtis Johnson, Yu Lei, Tianzhe Li, Kyuhak Oh, Shuo Wang, Chi Zhang, Su-Min Zhou
Affiliation: University of Nebraska Medical Center
Abstract Preview: Purpose: The purpose of this study was to leverage neural network visualization tools to detect high-attention areas indicative of treatment failure in lung SBRT by examining correlation matrices betw...
Authors: Jean Bourbeau, Jim Hogg, Miranda Kirby, Meghan Koo, Kalysta Makimoto, Wan Tan
Affiliation: Montreal Chest Institute of the Royal Victoria Hospital, McGill University Health Centre, Toronto Metropolitan University, Centre for Heart Lung Innovation, University of British Columbia
Abstract Preview: Purpose: Chronic obstructive pulmonary disease (COPD) exacerbations are burdensome to patients and healthcare systems. CT imaging-derived measures of emphysema and airway remodeling have been shown to...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
PET is used in radiotherapy workflows for accurate target delineation. However, a separate CT scan is typically required for attenuation correction in PET imaging and for registering PET-d...
Authors: Austen N. Curcuru, Arash Darafsheh, Winter Green, Yao Hao, Baozhou Sun, Tiezhi Zhang, Tianyu Zhao, Xiandong Zhao
Affiliation: WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Washington University in St. Louis, University of South Florida, Baylor College of Medicine
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) requires precise setup imaging due to the sharp dose gradients and rapid distal fall-off seen in proton therapy dose distributions. Additionally, onl...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose: In proton therapy, the substantial size of the gantry introduces sag, causing the proton isocenter to drift as a function of gantry angle. While the scanning magnets correct the beamâs isocen...
Authors: Arjit K. Baghwala, Sunan Cui, Jessica Fagerstrom, Eric C. Ford, Kristi Rae Gayle Hendrickson, Sharareh Koufigar, Samuel Ming Ho Luk, Bishwambhar Sengupta, Afua A. Yorke
Affiliation: University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, University of Vermont Medical Center, University of Washington and Fred Hutchinson Cancer Center, Houston Methodist Hospital
Abstract Preview: Purpose: The global burden of cancer continues to rise, leading to an increased workload in radiation oncology clinics. This surge is not only due to the growing demand for treatment machines and moda...
Authors: Kellin M De Jesus, Leon Dunn, Les Sztandera, David H. Thomas
Affiliation: IsoAnalytics Pty. Ltd., Thomas Jefferson University
Abstract Preview: Purpose: Machine accuracy and performance are critical for ensuring the safety and efficacy of intensity-modulated radiotherapy (IMRT and VMAT). This study aims to analyze a large and diverse set of l...
Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin
Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...
Authors: Sophie Boisbouvier, David Cobben, Anthony L Criscuolo, Michael W. Kissick, Mark Ramtohul, Gordon Sands, Tracy Underwood
Affiliation: University of Surrey, Department of Medical Physics, Queen Elizabeth Hospital, Lung Cancer and Sarcoma Radiotherapy, The Clatterbridge Cancer Centre, Leo Cancer Care, Radiotherapy department, Centre LĂ©on BĂ©rard
Abstract Preview: Purpose:
Pulmonary function tests (PFTs) help assess treatment options for lung cancer patients. Conventionally, these are undertaken upright, whereas radiotherapy is administered supine. This stud...
Authors: Ted Bartley, Steven Brown, Steven Chinn, Mike Hopkins, Stanley Leong, Jerimy C. Polf, Luke Rothermel, Scott Sawyer, Benjamin L. Viglianti
Affiliation: University of California School of Medicine, University of Michigan, H3D, inc, University Hospitals, M3D, Inc, M3D Imaging, California Pacific Medical Center
Abstract Preview: Purpose: In a collaboration between surgical oncologists and medical physicists, a new intra-operative gamma camera for imagining sentinel lymph nodes (SLN) during radio-guided SLN biopsy procedures h...
Authors: E Courtney Henry, Srinivas Cheenu Kappadath, Armeen Mahvash
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Characterization of hepatocellular carcinoma (HCC) tumor responses for single-arm single-center prospective 90Y-radioembolization clinical trial (n=40) that used patient-specific voxel-dos...
Authors: Mohamad Ahmad Alissa, Carson Brame, Damian Czarnecki, Olivier Evrard, Charbel A. Habib, Jeff Hildreth, Andy Murray, Andreas Schönfeld, Ann-Britt Schönfeld, David Towle, Gerd Wessing
Affiliation: CDT-West - Centrum fĂŒr Diagnostik und Therapie, Radiologie Vechta, Technische Hochschule Mittelhessen, MyMichigan Health, Sun Nuclear Corp., Mirion Technologies
Abstract Preview: Purpose: To characterize the performance of novel shielded and unshielded silicon diode detectors in relative photon and electron beam dosimetry.
Methods: The novel shielded and unshielded sili...
Authors: Brett G Erickson, Joseph P. Kowalski, Xinyi Li, Qiuwen Wu, Sua Yoo
Affiliation: Duke University, Mayo Clinic - Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: Characterization and commissioning of the BeO-based myOSLchip system was performed (per TG191) to assess its feasibility as a full replacement for the recalled Landauer aluminum oxide OSL in ...
Authors: Kainoa Calistro-Allen, Brendon J. Villegas
Affiliation: University of Alabama Birmingham
Abstract Preview: Purpose:
To compare differences in radiation output and image quality in clinical esophagrams across fluoroscope vendors in use at University of Alabama Birmingham, prompted by reports that a newly...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the âMyOSL Chipâ OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: Kaile Li, Esmail Parsai
Affiliation: Alexander T. Augusta Military Medical Center, Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To evaluate the sensitivity of the portal dosimetry system with the Arc CHECK system at identical Volumetric Modulated Arc Therapy (VMAT) setup
Methods: An Arc CHECK system from Sun Nuclea...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue, Yucheng Tang, Shiru Wang
Affiliation: NVIDIA Corp, Dartmouth College, Thayer School of Engineering, Dartmouth College, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: Cherenkov imaging allows for real-time visualization of megavoltage X-ray or electron beam delivery during radiation therapy. By using a time-gated intensified CMOS camera synchronized with a...
Authors: Jeremy Eric Hallett, Aubrey Parks, Brian W Pogue
Affiliation: University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging visualizes radiotherapy beams, assuming emission is proportional to deposited dose. However, attempts for Cherenkov as a quantitative dose estimation have been unsuccessful ...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Yesenia Gonzalez, Zohaib Iqbal, Paul M. Medin, Rameshwar Prasad, Chenyang Shen, Robert Timmerman, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Each year more than one million pacemakers and 200k cardioverter-defibrillators are implanted in patients worldwide. The presence of a CIED introduces challenges to the delivery of radiation ...
Authors: Ergun E. Ahunbay, Colette Gage, Abdul Kareem Parchur, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: AI-generated synthetic CT (sCT) images address challenges with prior sCT approaches, including atlas- and threshold-based methods. Commercial AI-based sCT tools have been introduced. This wor...
Authors: James Benton, Andrew Dewar, Benjamin C Lee, Ryan Y Lee
Affiliation: Radiotherapy Clinics of Georgia, Urology of Greater Atlanta
Abstract Preview: Purpose:
The purpose of our investigation was to determine if pre-treatment factors could predict urinary morbidity after combination radiation treatment for localized prostate cancer.
Methods:<...
Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Madeleine Arbogast, David Dorndos, Denise E Foltz, Justin Fraser, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Neurosurgery, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: For stereotactic radiosurgery (SRS) treatments of intracranial arteriovenous malformations (AVM) and fistulas (AVF), same-day Leksell Gamma Knife (GK) is the preferred modality. Long-term cli...
Authors: David L. Barbee, Paulina E. Galavis, Lena Adel Samad, Jose R. Teruel Antolin
Affiliation: NYU, NYU Langone Health
Abstract Preview: Purpose: To validate an automated script that converts treatment plans of varying Varian MLC models
Methods: A C# script was developed using the Eclipse Scripting API to convert treatment plans...
Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology
Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: Prompt gamma (PG) imaging is a promising modality for proton dose verification. Currently, there is a lack of effective tool to investigate the PG emission during proton therapy and optimize ...
Authors: Dan Giardina, John Karageorgiou, Chris Malone, Naganathan Mani, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Relative to planar imaging, MAA-SPECT/CT offers more reliable lung shunt fraction (LSF) and lung mean dose (LMD) estimates in 90Y radioembolization. But lung truncation in SPECT/CT can limit ...
Authors: ISAAC Amoah, Jackie Austin, Charlotte Block, Kaylee Brilz, Dylan Bui, Andrew E. Ekpenyong, Jayce Hughes, Natasha Ratnapradipa, Sara Strom, Jacob Woolf
Affiliation: Creighton University
Abstract Preview: Purpose: Cancers of the brain and nervous system account for 1 in 100 cancer diagnoses in the US every year. Surgery, radiotherapy, and chemotherapy constitute the standard of care. For Glioblastoma (...
Authors: Yibin Ling, Qihui Lyu, Ke Sheng
Affiliation: University of California Berkeley, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
High Dose Rate (HDR) brachytherapy enables radiation to concentrate on the tumor by sending the high-dose-rate radioactive source directly to the treatment site. On the other hand, the sha...
Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...
Authors: Maria Jose Almada, Carlos Bohorquez, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA is crucial in maintaining patient safety, typically depending on dosimetric measurements. However, advancements in computational technology have highlighted the growing significance o...
Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...
Authors: Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: The objective of this study is to systematically evaluate and validate the performance of a commercially available 3D Linear stage device as a quality assurance (QA) tool to validate position...
Authors: Michalis Aristophanous, Steven Blum, Laura I. Cervino, Antonio L. Damato, Karen Episcopia, Chi Huang, Shih-Chi Lin, Michelle K. Savacool
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Varian Ethos (Varian Medical Systems, Palo Alto, CA) is a 6 MV flattening-filter-free (FFF) only machine, posing a challenge in creating homogeneous dose distributions when using manual 3D-CR...
Authors: Maria F. Chan, Indra J. Das, Xiuxiu He, Seng Boh Gary Lim, Jeonghoon Park, Yunjie Yang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: There is a need for accurate and flexible in-vivo dosimetry systems, particularly for special procedures. Effective dosimetry is crucial for dose verification and maintaining records. A new r...
Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...
Authors: Serdar Charyyev, Cynthia Fu-Yu Chuang, Veng Jean Heng, Lianli Liu, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: To replace large finite-size photon phase space files with a compact neural network capable of generating an infinite number of particles.
Methods: Three separate models were developed to ...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Elsa Bifano Pimenta
Affiliation: University of SĂŁo Paulo (USP), Institute of Physics
Abstract Preview: Purpose: This study evaluates the similarity between the linear attenuation coefficients of soft tissues and 3D printing materials in diagnostic imaging range using the Euclidean distance approach.
Authors: Theodore Higgins Arsenault, Beatriz Guevara, Rojano Kashani, Raymond F. Muzic, Gisele Castro Pereira, Alex T. Price
Affiliation: University Hospitals Seidman Cancer Center, Case Western Reserve University Department of Biomedical Engineering
Abstract Preview: Purpose: Accurate dose prediction in radiotherapy is essential for treatment planning. This study evaluates four nnUnet-based models using the OpenKBP head and neck dataset: a baseline model (Model 1)...
Authors: Chang Heon Choi, Yoonsuk Huh, Jin Jegal, Seonghee Kang, Jung-in Kim, Inbum Lee, Hyojun Park
Affiliation: Department of Radiation Oncology, Seoul National University Hospital
Abstract Preview: Purpose: This study evaluates SpekPy, a Python-based tool for modeling kilovoltage (kV) x-ray spectra, by comparing its calculated energy spectra, half-value layer (HVL), and air kerma with experiment...
Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...
Authors: Srinivas Cheenu Kappadath, Brian Michael Kelley, Benjamin P. Lopez
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Imaging systems are subject to errors from finite spatial resolution and voxel size. This work demonstrates their effect on dose algorithm {Monte Carlo (MC), dose-volume kernel (DVK), and ...
Authors: Wenwen Bai
Affiliation: The Fourth Hospital of Hebei Medical University
Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...
Authors: David J. Carlson, Yiu-Hsin Chang, Zhe (Jay) Chen, Hyosung Cho, Dae Yup Han, MinYoung Lee, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose:
To compare the intra-fractional motion tracking sensitivity of prostate fiducial markers using triggered imaging and calypso tracking for prostate cancer cases.
Methods:
This study w...
Authors: Jonathan J. Chen, Alexei V. Chvetsov, Yulun He, Ramesh Rengan, Andrew Stacey, Kent Wallner
Affiliation: University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To show that the RBE of low-energy photon sources used in COMS (Collaborative Ocular Melanoma Study) eye plaques compensates for protracted irradiation and attenuation of low-energy photons i...
Authors: Sarah Aubert, Harald Keller, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: Support for treatment planning directly on CBCT imaging on C-arm linacs will enable adaptive radiation therapy (ART) capacity with increased treatment technique flexibility. The HyperSight im...
Authors: Jacinta E. Browne, Tzu Cheng Chao, Ajit Deveraj, Ece Ercan, Tim Leiner, Alessio Perazzolo, Michal Povazan, Jouke Smink, Camilla Vita, Spencer Waddle, Dinghui Wang
Affiliation: UniversitaÌ Cattolica del Sacro Cuore, Philips Healthcare, Mayo Clinic
Abstract Preview: Purpose:
In recent years, mid-field MRI has shown promise to meet the technical demands of cardiac imaging1. Mid-field strengths offer advantages to CMR due to shorter T1-relaxation times, lower sp...
Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...
Authors: Nathalie Correa, Janet Ching-Mei Feng, Chun-Han Huang, Jimmy Huynh
Affiliation: UTHealth McGovern Medical School
Abstract Preview: Purpose: To compare the image quality and the dose-area product (DAP) of four mobile digital radiography (DR) systemsâCanon (Soltus 500), Shimadzu (MobileDaRt Evolution MX8), Solution for Tomorrow (M1...
Authors: Junsheng Cao, Khushdeep Singh
Affiliation: Overlook Medical Center
Abstract Preview: Purpose: Eclipse v18 introduces Enhanced Leaf Modeling for MLCs. This study investigates the MLC off-axis characteristics using portal dosimetry
Methods:
MLC characteristics were analyzed for th...
Authors: Tianyuan Dai, Zejun Jiang, Xiangyue Kong
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
This study aims to evaluate the reliability of SFRT-VMAT plan verification by comparing two QA methods: Portal Dosimetry (PD) and Delta4Âź.
Methods:
Preteatment QA was conducted for 1...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....
Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: The purpose of this study was to investigate the interplay effect during intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intens...
Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago
Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...
Authors: Ziyad ABUBAKR ALHAREESHi, Ibtihaj Yussef Alhodire, Najla Sobhi Bin Shehima, Aram Mufteh A Genaw
Affiliation: Tripoli university hospital
Abstract Preview: Purpose:
This research investigates the recombination and polarity correcting factors for CC04, CC13, FC65P, FC65G, Razor, and PP05 ionization chambers to improve radiation dosimetry accuracy. Unde...
Authors: Gourav Jhanwar, Mojtaba Tefagh, Masoud Zarepisheh
Affiliation: The University of Edinburgh, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Radiotherapy treatment planning involves solving computationally-intensive and time-consuming optimization problems. Central to these problems is a large matrix known as the dose-influence...
Authors: Baher Elgohari, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Jeonghoon Park, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, UPMC, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
To compare toxicity between consecutive-daily (QD) with every-other-day (QoD) delivery of lung stereotactic-body-radiation (SBRT) for central non-small-cell lung cancer (NSCLC).
Methods...
Authors: Nrusingh C. Biswal, Sally Cheston, Sung-Woo Lee, Weiguang Yao, Baoshe Zhang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: The deep inspiration breath-hold (DIBH) technique in left breast radiation reduces doses to critical organs such as the heart, left lung, and left anterior descending artery (LAD). With the a...
Authors: Niki Fitousi, Anna Romanyukha, Stuart Utting
Affiliation: University Hospitals Dorset, Qaelum NV
Abstract Preview: Purpose:
For increased patient safety and with a focus on sustainability in the radiology department, efforts are being made to optimize contrast media usage. In this study, the possibility of util...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Iterative reconstruction (IR) methods are valuable for reducing dose in modern CT; however, IR methods have the effect of reducing spatial resolution and hence the lesion edge sharpness. Furt...
Authors: Abdusalam Abdukerim
Affiliation: Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Coronary computed tomography angiography (CCTA) is the gold-standard non-invasive test for coronary artery disease (CAD), but iodine contrast agents (ICA) pose limitations in specific popu...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose: Convergence speed is crucial for an optimizer. Faster convergence leads to better solutions with fewer iterations and less time. Recently, a machine learning (ML)-assisted framework employing...
Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller
Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration
Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study examines the correlation of different dose volume metrics of the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) structures with the skin systemic sclerosis...
Authors: Nrusingh C. Biswal, Matthew J Ferris, Michael J. MacFarlane, Jason K Molitoris, Byong Yong Yi, Mark J. Zakhary
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose: Proton head-and-neck treatment plans often struggle to maintain plan quality over the course of treatment due to tumor response, weight-loss, and setup variability. Plan robustness to these c...
Authors: Seung Yeon Kim, Grant A. McAuley, Ju A Park, Jerry D Slater
Affiliation: Loma Linda University
Abstract Preview: Purpose: The production of proton minibeams in standard PBS nozzles is challenging due to the effects of finite source beam divergence and multiple Coulomb scattering. Herein we investigate the use of...
Authors: Zachary R. Grelewicz, Kevin C. Jones, Yixiang Liao, Andrew Ogilvy, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To demonstrate the accuracy and QA application of a time-resolved 3D gamma camera, we measured the path traversed by the Ir-192 High-Dose-Rate (HDR) brachytherapy source passing through a rin...
Authors: Klaus Bacher, Tom Boterberg, Jeff Rutten, Barbara Vanderstraeten, Gwenny Verfaillie, Sarah Waelkens
Affiliation: Ghent University, Ghent University Hospital
Abstract Preview: Purpose: Lymphoma cancer patients frequently receive ionizing radiation during their treatment trajectory, including diagnostic CT, planning CT (pCT), recurrent CBCTs, radiotherapy (out-of-field) dose...
Authors: Derek Tang, Susu Yan
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To evaluate the performance of a multi-task automated-segmentation and synthetic CT generation model (sCT) and investigate its application in an adaptive proton therapy workflow.
Methods: ...
Authors: Hector Andrade-Loarca, Ines Butz, Chiara Gianoli, Prof. Gitta Kutyniok, Jianfei Li, Katia Parodi, Prof. Vincenzo Patera, Angelo Schiavi, Prof. Ozan Ăktem
Affiliation: Sapienza University of Rome, Department of Mathematics, Royal Institute of Technology, School of Computation, Information and Technology, Technische Universitaet Muenchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Department of Mathematics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen
Abstract Preview: Purpose: To explore and demonstrate the feasibility of accurate and fast prediction of the water equivalent thickness (WET) distribution of tissue traversed by a proton imaging pencil beam, aiming at ...
Authors: Zhuo Chen, Tinsu Pan, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, WashU Medicine, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Misregistration between data-driven gated (DDG)-PET and CT can limit the benefits of motion correction and improved localization and quantitation. DDG-CT offers a solution to these issues. He...
Authors: Robbie Beckert, Austen N. Curcuru, Farnoush Forghani, Yi Huang, Geoffrey D. Hugo, Hyun Kim, Eric Laugeman, Luke Christian Marut, Thomas R. Mazur, Allen Mo, Emily Sigmund
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine in St. Louis, Wash U Medicine, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: Adaptive SBRT is resource intensive, requiring additional personnel for online planning, and should be reserved for cases where it is most beneficial. The purpose of this research is to creat...
Authors: Carri K. Glide-Hurst, Thomas M Grist, Kevin M. Johnson, Prashant Nagpal, Tarun Naren, Chase Ruff, Oliver Wieben, Jiwei Zhao
Affiliation: Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison, Department of Radiology, University of Wisconsin-Madison, Department of Medical Physics, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison
Abstract Preview: Purpose: Cardiotoxicity is a devastating side effect for thoracic radiotherapy (RT). Currently, standard RT imaging is insufficient to decouple cardiorespiratory motion, limiting substructure-specific...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...
Authors: Ryan Andosca, Peter Boyle, Minji Victoria Kim, Michael Vincent Lauria, Daniel A. Low, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Dylan P. O'Connell, Ricky R Savjani
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, UCLA, University of California, Los Angeles, UCLA Radiation Oncology
Abstract Preview: Purpose: To demonstrate the performance of the model-based CT scanning protocol, 5DCT, as an alternative to 4DCT.
Methods: 5DCT imaging results for 242 patients were analyzed. Implementation of the...
Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer
Affiliation: RaySearch Laboratories, Moffitt Cancer Center
Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...
Authors: Laila A Gharzai, Bharat B Mittal, Poonam Yadav
Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Multiple studies have shown the increasing role of deep learning in segmenting regions of interest. This work presents the feasibility of auto-segmenting the critical structures for head and ...
Authors: Weikang Ai, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Real-time tumor tracking is critically important for respiratory motion management for lung cancer radiotherapy. A previously proposed application of a photon counting detector involves measu...
Authors: Yaspal Badyal, Rabten Datsang, Tianjun Ma, William Song
Affiliation: MVision AI, Virginia Commonwealth University
Abstract Preview: Purpose: Deep learning (DL)-based dose distribution predictions for prostate cancer show significant potential for OAR sparing compared to manually optimized treatment plans. We aim to generate clinic...
Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang
Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...
Authors: Gary Y. Ge, Abdullah-Al-Zubaer Imran, Kazi Ramisa Rifa, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: With renewed attention on CT radiation dose management following CMS approval of new dose measures, establishing image qualityâbased target doses for every protocol has become essential. Whil...
Authors: Zixu Guan, Takahiro Iwai, Takashi Mizowaki, Mitsuhiro Nakamura, Michio Yoshimura
Affiliation: Kyoto University, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose:
The goal of this study is to develop a fully automated treatment planning approach for VMAT in pancreatic cancer that can convert patient anatomy into LINAC machine parameters. In this wor...
Authors: Chih-Wei Chang, Runyu Jiang, Mark Korpics, Yuan Shao, Aranee Sivananthan, Zhen Tian, Ralph Weichselbaum, Xiaofeng Yang, Aubrey Zhang, Xiaoman Zhang
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Department of Physics, University of Chicago, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, School of Public Health, University of Illinois Chicago
Abstract Preview: Purpose: Gamma Knife (GK) plan quality can vary significantly among planners, even for cases handled by the same planner. Although plan quality metrics such as coverage, selectivity, and gradient inde...
Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma
Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC
Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...
Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita
Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital
Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...
Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...
Authors: Sang Hee Ahn, Nalee Kim, Do Hoon Lim
Affiliation: Samsung Medical Center, Department of Radiation Oncology, Samsung Medical Center, Sungkyunkwan University School of Medicine
Abstract Preview: Purpose: MRI offers superior soft-tissue contrast, aiding tumor localization and segmentation in radiation therapy, which traditionally relies on oncologists' expertise. This study compares CNN-based ...
Authors: Ahssan Balawi, Peter Jermain, Timothy Kearney, Sonali Rudra, Michael H. Shang, Markus Wells, Mohammad Zarenia
Affiliation: Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: To investigate the applicability and accuracy of a deep learning (DL) model in predicting radiation dose distribution for breast cancer patients treated with pencil-beam-scanning proton radio...
Authors: Xinyi Fu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...
Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic
Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...
Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. Göksel, Görkem O. GĂŒngör, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan
Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman Sönmez Oncology Hospital
Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Imad M. Ali, Nesreen Alsbou, Baraa Kalani
Affiliation: Oklahoma State University, University of Central Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: To develop a three-dimensional Winston-Lutz phantom to quantify the isocentricity of the gantry, couch, and on-board imager of the MEVION-S250i proton therapy machine.
Methods: A 3D-scinti...
Authors: Alexander Baikalov, Luke Connell, Nicholas Coupey, Nolan M. Esplen, Rebecca Lim, Chinh Nguyen, Emil Schueler
Affiliation: Northwell, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: FLASH radiotherapy delivered using electron linear accelerators (LINAC) requires precise control and minimal variation of dose rate and We developed a robust external beam control system (EBC...
Authors: Edward A. Opalko, Matthew B. Podgorsak, Dheerendra Prasad
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To design a 3D printed insert for Varianâs SRS Head Phantom that allows for multi-planar film dosimetry and to evaluate its ability in end-to-end testing for Gamma Knife treatments.
Method...
Authors: Go Akamatsu, Yuma Iwao, Kurumi Narita, Hideaki Tashima, Taiga Yamaya, Eiji Yoshida
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In brain positron emission tomography (PET), higher spatial resolution is better for visualizing detailed structures such as small nuclei and the layered structure of the cerebral cortex. The...
Authors: Zongsheng Hu, Yuting Li, Radhe Mohan, Emil Schueler, Uwe Titt
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: In previous work, we developed an irradiation system for pre-clinical ultra-high-dose-rate(FLASH) radiotherapy experiments based on synchrotron proton beamline. However, the beam current limi...
Authors: Javier Chiasson, Dominique Guillet, Arthur Lalonde, Bryan R. Muir, James Renaud, Karim Zerouali
Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal, National Research Council
Abstract Preview: Purpose: To develop, optimize and validate a novel applicator for ultra-high dose rate (UHDR) electron radiotherapy incorporating an electrostatically shielded beam current transformer (BCT) for real-...
Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo
Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...
Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Massachusetts General Hospital
Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...
Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang
Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale
Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...
Authors: Clifford Ghee Ann Chua, Calvin Wei Yang Koh, Kah Seng Lew, Zubin Master, Sung Yong Park, Hong Qi Tan, Andrew Wibawa
Affiliation: National Cancer Centre Singapore
Abstract Preview: Purpose: To investigate the impact of spot position deviation on reference dosimetry measurements using different delivery patterns and to determine the optimal delivery pattern for reference dosimetr...
Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patientâs nose relative to two stationary reflectors on th...
Authors: Ashley Elizabeth Bonner, Michael G. Snyder
Affiliation: Corewell Health William Beaumont University Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: Develop and evaluate metrics for assessing beam matching of profiles across Elekta linacs in a multisite clinical setting.
Methods: Four Elekta linear accelerators (three VersaHD and one A...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Mustafa Bashir, Diana Kadi, Kyle J. Lafata, Jacob A. Macdonald, Mark Martin, Yuqi Wang, Marilyn Yamamoto
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Electrical and Computer Engineering, Duke University, Department of Radiology, Duke Unversity
Abstract Preview: Purpose: To develop a high-throughput, automated-data-interrogation pipeline for integrating imaging and clinical information to identify key determinants of liver volume (LV), enabling population-sca...
Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...
Authors: Chase Cochran, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...
Authors: Julia Bauer, Tianxue Du, Katia Parodi, Marco Pinto, Thomas Tessonnier
Affiliation: Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Heidelberg Ion Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich)
Abstract Preview: Purpose:
Carbon ion therapy could benefit from range verification due to its sensitivity to range uncertainties. Positron emission tomography (PET) aids in this and comparing irradiation-induced PE...
Authors: Hyo-Min Cho, Cheolpyo Hong, Changwoo Lee, Sunyoung Lee
Affiliation: Daegu Catholic University, Korea Research Institute of Standards and Science (KRISS), Korea Research Institute of Standards and Science
Abstract Preview: Purpose: With the increasing prevalence of metabolic syndrome, the importance of diagnosing obesity and fatty liver diseases has grown significantly. As a result, there is a rising demand for non-inva...
Authors: Md. Jobairul Islam
Affiliation: Department of Radiation Oncology, Labaid Cancer Hospital and Super Speciality Centre
Abstract Preview: Purpose: Electron radiotherapy is an effective treatment for superficial tumors but requires field-shaping devices like electron applicators, which are labor-intensive to produce. This study aimed to ...
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Childrenâs Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Childrenâs Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Childrenâs Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Wesley E. Bolch, Lotem Buchbinder Shadur, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Shaheen Dewji, John Francis, Emmanual Mate-Kole, Wyatt Smither, Yitian Wang
Affiliation: Georgia Tech, University of Florida, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: Develop a software application capable of assessing the radiation contamination of military service members and members of the general public for fast, on-site radiological triage. The softwa...
Authors: Alejandro Bertolet, Isaac Meyer, Harald Paganetti, Jan PO Schuemann, Wook-Geun Shin
Affiliation: Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a methodology for Monte Carlo modeling of cell-specific DNA geometries based on Hi-C data using TOPAS-nBio, and to evaluate early DNA damage distributions.
Methods: Hi-C data of...
Authors: Adedamola Adeniyi, Bryan Bednarz, Malick Bio Idrissou, Reinier Hernandez, Ohyun Kwon, Brian W. Miller, Zachary S Morris, Maya Takashima, Jamey Weichert
Affiliation: Departments of Radiation Oncology and Medical Imaging, University of Arizona, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Medical Physics, School of Medicine and Public Health, University of WisconsinâMadison, Department of Radiology, School of Medicine and Public Health, University of WisconsinâMadison, Department of Human Oncology, School of Medicine and Public Health, University of WisconsinâMadison
Abstract Preview: Purpose: As radiopharmaceutical therapy (RPT) becomes more prevalent in clinical applications, understanding dose-response relationships in the tumor microenvironment (TME) and normal tissues is essen...
Authors: Kaile Li
Affiliation: Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To develop a experimental method in observation of beam profile transfer model in intensity modulated radiotherapy (IMRT).
Methods: A picket fence plan was generated in Eclipse treatment p...
Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo
Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...
Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda
Affiliation: McMaster University
Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...
Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan
Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China
Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...
Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Laura Dinwiddie, Benjamin Taylor Heggie, Adam Leon Kesner, Juan Camilo Ocampo Ramos, Graham Joseph Stoddard
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson
Abstract Preview: Purpose: The objective of this study is to develop a physical phantom to quantify tube current modulation (TCM) and assess the limitations of a TCM model used in Monte Carlo patient CT organ dose esti...
Authors: Kaelyn Becker, Xenia Ray
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: Ethos 2.0 with HyperSight (Varian Medical Systems) imaging enables nearly fully automated offline adaptive radiotherapy including automated deformation of targets and recalculation on the Hou...
Authors: Jung Han Nam, Wonmo Sung
Affiliation: Department of Biomedical Engineering and Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Department of Biomedical Engineering and Biomedicine & Health Sciences, College of Medicine, The Catholic University of Korea, Seoul, Korea
Abstract Preview: Purpose: This study aims to develop a whole-body blood flow framework based on the ICRP 145 standard vascular phantom to simulate the spatiotemporal trajectories of blood cells in the human vasculatur...
Authors: Somayeh Gholami, Saeedeh Ketabi, Jeremy Kunz, Ali Yousefi
Affiliation: Department of Radiation Oncology, University of Utah, University of Utah, Department of Management- Operations Research, University of Isfahan
Abstract Preview: Purpose: This paper aims to present a novel approach for automatic knowledge-based planning optimization for Intensity Modulated Radiotherapy, along with the two downsizing techniques for improving th...
Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao
Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...
Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng
Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...
Authors: Penghao Gao, Zejun Jiang, Huazhong Shu, Linlin Wang, Gongsen Zhang, Jian Zhu
Affiliation: Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration, Southeast University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: We propose a cascading framework for time-varying anatomical volumetric reconstruction and tumor-tracking, guided by onboard orthogonal-view X-ray projections.
Methods: We employe multiple...
Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom
Affiliation: Brigham and Womenâs Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School
Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...
Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma
Affiliation: University of Pennsylvania, Mayo Clinic
Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...
Authors: Luke Connell, Nolan M. Esplen, Elise Konradsson, Albert C. Koong, Ziyi Li, Steven Hsesheng Lin, Kevin Liu, Billy W Loo, Devarati Mitra, Radhe Mohan, Emil Schueler, Takeshi Takaoka, Uwe Titt, Xiaochun Wang, Ming Yang
Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study aimed to assess radiation-induced gastrointestinal (GI) toxicity in mice subjected to abdominal irradiation using protons at ultra-high-dose-rate (UHDR) and conventional dose-rates...
Authors: Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Development of a novel spatially fractionated radiotherapy (SFRT) lattice deployment method featuring a large high-dose sphere at the tumorâs center, surrounded by smaller diameter spheres. W...
Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...
Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...
Authors: Michael Buckstein, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Inter-fraction anatomic variations in liver SBRT can cause significant discrepancies between planned and delivered doses. We developed a CBCT-based accumulative algorithm to directly compare ...
Authors: Michael Lamontagne, Ileana Pazos, Jerimy C. Polf, Joseph W. Robertson, Teniola Tobun, Ronald E. Tosh, Michael Zwolak
Affiliation: Biophysics and Biomedical Research Group, Microsystems and Nanotechnology Division, National Institute of Standards and Technology, M3D, Inc, National Institute of Standards and Technology, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To study how damage to DNA molecules increases and changes as a function of the type and dose of radiation.
Methods: DNA molecules of a known length (number of base pairs (BP)) within ...
Authors: Christopher Ackerman, Chang Chang, Yansong Liu, Stephen Kenneth Northway, Bailey Vallejo
Affiliation: University of California San Diego / California Protons, California Protons Cancer Therapy Center, California Proton Cancer Therapy Center
Abstract Preview: Purpose: To determine mechanical isocenter of a 6-degree-of-freedom (6DOF) couch using radiation isocenter. Coincidence between the isocenters is quantified using MyQA Phoenix amorphous silicon detect...
Authors: Theresa Busch, Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Brian C. Wilson, Weibing Yang, Timothy C. Zhu
Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: Direct detection of singlet-state oxygen (ÂčOâ) is crucial for advancing type II photodynamic therapy (PDT), but its short lifetime makes in vivo measurement highly challenging. Although Photo...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Haley K Perlow, Alex T. Price, Atefeh Rezaei, Prashant Vempati, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: The HyperSight imaging feature on C-arm linacs(HS-CBCT) offers increased CT number accuracy over conventional on-board imaging. The C-arm geometry allows for noncoplanar treatments common to ...
Authors: Indra J. Das, Ahtesham Ullah Khan, Andrew J. White
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Small field dosimetry presents challenges due to lateral disequilibrium and the selection of suitable detectors. Volume averaging and density corrections hamper accurate profile measurements....
Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Childrenâs Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Childrenâs Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Ana Laura Burin, Maysa MĂŒller Ferreira Gesserame, David Alexander Urbina Leal, Ilca Marli Moitinho Amaral Medeiros, Silas Leonel Pereira Miranda, Thuany CorrĂȘa Nogueira, Maria da Penha Alburquerque Potiens, Pedro Henrique Ricardo, Maria Eduarda Zaganin Rigo, Orlando Rodrigues, Priscila Santos Rodrigues, Wilmmer Alexander Arcos Rosero, Maria Elisa Chuery Martins Rostelato, Sabrina Spigaroli Sgrignoli, Ana Catarina Koka de Souza Silva, Cristhian Ferreira Talacimon, Paulo Victor dos Santos Tavares, Lara El Hajj Teodoro, Carlos Alberto Zeituni, JosĂ© Neres de Almeida
Affiliation: IPEN - USP
Abstract Preview: Purpose: Perform three-dimensional dosimetry of radioactive gold nanoparticles (ÂčâčâžAuNPs) using Fricke xylenol gel (FXG), aiming to determine the dose distribution and evaluate the method's effectiven...
Authors: Motohiro Kawashima, Adrian Kugara, Masao Nakao, Shuichi Ozawa, Mutsumi Tashiro, Maria Varnava
Affiliation: Gunma University Heavy Ion Medical Center, Hiroshima High-Precision Radiotherapy Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the time-dependent dose rate characteristics of a scanning carbon ion beam using a fast-response plastic scintillator detector (PSD), with a focus on its potentia...
Authors: Xiance Jin
Affiliation: 1st Affiliated Hospital of Wenzhou Medical University
Abstract Preview: Purpose:
Deep learning deformable registration models was proposed to predict optimal dose distributions a with a few of optimal planned doses using a few-shot learning for cervical cancer.
Meth...
Authors: Woong Cho, Jin-Beom Chung, Moo-Jae Han, Sang Won Kang, Boram Lee
Affiliation: Department of Radiation Oncology, Seoul National University Boramae Medical Center, Department of Radiation Oncology, Seoul National University Bundang Hospital, Department of Radiation Oncology, Inha University Hospital
Abstract Preview: Purpose: This study aims to establish a digital quality assurance (QA) system for high-dose-rate (HDR) brachytherapy by evaluating self-developed polycrystalline semiconductor dosimeters (PSDs).
Me...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Aliasghar Rohani, Rui Zhang
Affiliation: Louisiana State University, Baton Rouge, Louisiana, Department of Radiation Oncology, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the impact of simultaneous optimization of multi-photon beam energy and fluence on IMRT and VMAT treatment planning.
Methods: An Elekta linear accelerator (lin...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo
Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre
Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...
Authors: Justus Adamson, Wesley Andrew Cunningham, Chang-Sei Kim, Yeongoh Ko, Anna E. Rodrigues
Affiliation: Duke University, Chonnam National University, Duke University Medical Center
Abstract Preview: Purpose: Radiation induced toxicities in bowel remains a challenge for SBRT. Due to sharp dose falloffs, small displacements of the bowel can lead to meaningful dose reduction. Remote magnetic navigat...
Authors: Jordan B Lunsford, Sagar Pokhrel, Ashkan Shafiee, Curtis S. Whiddon
Affiliation: Atrium Health Wake Forest Baptist, University of North Carolina, Atrium Health Wake Forest Baptist High Point Medical Center
Abstract Preview: Purpose: To investigate the dosimetric characteristics of a platinum cured silicone rubber material (Platsil) for use as custom bolus in radiotherapy
Methods: Sheets of 2, 4, 6, and 8 mm Platsil we...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Arnab Chakravarti, Nilendu Gupta, Sagarika Jain, Maximilian Stephen Meineke, Allison N. Palmiero, Runhe Tan
Affiliation: The Ohio State University - James Cancer Hospital, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, The James Cancer Center
Abstract Preview: Purpose: Ultra-High Dose Rate Radiation Therapy (UHDR-RT) induces normal tissue sparing while maintaining iso-effective tumor control compared to conventional methods, known as the âFLASH effectâ. How...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectorsâą for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Michael Leyva, Alejandro Rene Llanes Lopez, William Romaguera, Ranjini P. Tolakanahalli, Deborah Wang
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose: To evaluate whether a modulated electron bolus (MEB) technique improves both nominal and shifted dose distributions in nasal electron therapy as compared to a nonâmodulated, uniformâthickness...
Authors: Amar K. Basavatia, Sandeepan Ganguly, Lee C. Goddard, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To investigate the dosimetric impact of WGTG51-e Report 385, recently updated CoP for clinical electron beams. This study uses a chamber specific effective point of measurement (EPOM) shift t...
Authors: Ahmad Amoush, Adam C. Riegel
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: To investigate the dosimetric differences between the reference CT plan, the scheduled plan, and the adaptive plan for a bladder cancer patient treated with Varian Ethos system.
Methods: A...
Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre
Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...
Authors: Ian J. Butterwick, Sumudu Katugampola, ChangSeon Kim, Evan G. Meekins, Zhengdong Zhang
Affiliation: Mount Sinai Beth Israel, Gesinger Medical Center, Geisinger Medical Center
Abstract Preview: Purpose: To evaluate the dosimetric impact of enhanced dynamic leaf gap (EDLG) modeling in Eclipse V18.0 on small-field dosimetry within VMAT plans.
Methods: Plans with small fields (1 cm x 1 cm to...
Authors: Sumanta Manna, Atul Mishra, Surendra Prasad Mishra, Kailash Kumar Mittal, Anoop Kumar Srivastava, Neha Yadav
Affiliation: Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Department of radiation Oncology, Apollomedics Super Speciality Hospitals, Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Department of Radiation Oncology, Kalyan Singh Super Specialty Cancer Institute
Abstract Preview: Purpose: This study aimed to assess the dosimetric performance of Volumetric Modulated Arc Therapy (VMAT), step-and-shoot Intensity-Modulated Radiation Therapy (ss-IMRT), and dynamic Intensity-Modulat...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko SalomĂłn Alva SĂĄnchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Hsiao-Mei Fu, Shih-Ming Hsu, Chia-Ting Lee, Shih-Hua Liu, Tsung-Yu Yen
Affiliation: National Yang Ming Chiao Tung University, Mackay Memorial Hospital
Abstract Preview: Purpose: The Automatic Lower Dose Objective (ALDO) is a unique function designed to achieve 98% relative coverage across all targets in automated SRS treatment planning (HyperArc planning). This study...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: Kathryn J. Dess, Martha M. Matuszak, Dan Polan
Affiliation: University of Michigan
Abstract Preview: Purpose: A recent survey demonstrated 18 of 20 top academic institutions have implemented auto-segmentation. Studies to date have focused on geometric contour changes and dosimetric differences using ...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZAP-X is the newest cranial stereotactic radiosurgery (SRS) platform. Small-volume structures usually found in the head and neck may be susceptible to dose-volume averaging, which has not bee...
Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaël Ndoutoume-Paquet, Jan P. Seuntjens, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, Princess Margaret Cancer Centre & University of Toronto, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Nuclear Medicine Department, Hospital Regional de Antofagasta, Université Laval, Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University
Abstract Preview: Purpose: Low-energy X-ray beams used in electronic brachytherapy (eBT) pose unique dosimetric challenges due to high depth-dose gradients, material-dependent detector responses, and the absence of sta...
Authors: Lining Chen, Zhitao Dai, Shumei Jia, Yajun Jia, Enzhuo Quan
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen HospitalïŒ Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: This work reviewed 12 patient clinical LRT treatments in physics view including geometric and dosimetric parameters and discussed the pros and cons related to the latter.
Methods: Geometri...
Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng
Affiliation: New York Proton Center, Scarsdale High School
Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...
Authors: Makunda Aryal, Gregory Bartlett, David D. Campos, Ke Colin Huang, Sook Kien Ng, Christopher F. Njeh, Oluwaseyi Oderinde, Edwin Quashie, Ashok Tiwari, Yong Yue
Affiliation: Purdue University, Department of Radiation Oncology, Indiana University, Indiana University, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose:
Linear accelerator-based single-isocenter Stereotactic Radiosurgery (SRS) is widely used for treating brain metastases due to its efficiency, reduced treatment time, and lower imaging dose...
Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center
Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...
Authors: Darren Kaplan, Chenguang Liu, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center
Abstract Preview: Purpose: This study evaluates the hypothesis that surface-guided radiation therapy for the breast or chest wall using proton PBS provides comparable target coverage and OARs sparing to x-ray-based IGR...
Authors: Matthew Stephen Andriotty, Chi Ma, Xiao Wang, Keying (Karen) Xu, Suhong Yu, Ning J. Yue, Yin Zhang
Affiliation: Brigham and Women's Hospital, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To evaluate the effects of overlapping CT reconstruction on dosimetry calculation for LINAC-based SRS patients simulated on CT simulators from three different vendors.
Methods: CT simulati...
Authors: Lotem Buchbinder Shadur, Shaheen Dewji, Martin Graffigna, Alejandro Rafael Martinez, Emmanuel Mate-Kole, Antonio McClain, Samuel Taylor, Jeffrey Wang
Affiliation: Student, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: DosInMe is an internal dosimetry visualization tool developed by the Radiological Engineering, Detection, and Dosimetry Laboratory at Georgia Tech to assist researchers and professionals in v...
Authors: Michael J. Choi, Vindu Wathsala Kathriarachchi, Christopher L. Nelson, Andrew P. Soderstrom, Yawei Zhang
Affiliation: The University of Texas MD Anderson Cancer Center, MD Anderson, UF Health Proton Therapy Institute
Abstract Preview: Purpose: Cone Beam Computed Tomography (CBCT) is widely used in image-guided radiation therapy for patient positioning. While kV photons offer high image contrast, they are prone to artifacts caused b...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yabo Fu, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Boris Mueller, Huiqiao Xie, Mitchell Yu, Hao Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Gating ablative radiotherapy for pancreatic cancer accounts for tumor movement due to respiration and typically requires 5, 15, or 25 fractions. Pretreatment imaging verification is essential...
Authors: Daniel A. Alexander, Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Casey Hollawell, William Levin, Maksym Sharma, Boon-Keng Kevin Teo, Ying Xiao, Nikhil Yegya-Raman, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: To investigate lung function changes following definitive chemoradiation dose using CT-derived measurements in patients with locally advanced NSCLC at 6-months post-treatment compared to pre-...
Authors: James E. Bates, Benjamin Hopkins, Kirk Luca, Shadab Momin, Justin R. Roper, Soumon Rudra, Eduard Schreibmann, Bill Stokes, Tu Thi, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Swallowing dysfunctions after radiotherapy are caused by multiple factors yet are strongly associated with the irradiation of pharyngeal musculature due to its role in the initiation and comp...
Authors: Jingying Lin, Stevan Pecic, Strahinja Stojadinovic
Affiliation: University of Belgrade, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: This study aims to determine the magnitude of polarization-induced dosimetric error for EBT4 films at different scanning orientations, and to provide guidance on selecting appropriate regions...
Authors: Maciej M. Kmiec, Periannan Kuppusamy, Ryan C. O'Connell, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: The rigid needle-like EPR sensor, OxyTrack, was developed to provide minimally invasive, reliable, and quantitative measurements of oxygen distribution (pO2) in deep tissues. EPR oximetry's c...
Authors: Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Rojano Kashani, Kyle O'Carroll, Gisele Castro Pereira, Christian Erik Petersen, Alex T. Price, Meiying Xing, Reine abou Zeidane
Affiliation: university hospital, University Hospitals Seidman Cancer Center
Abstract Preview: Purpose:
Experimental data have shown the inconsistent monitor unit and target coverage in Ethos 1.1. This can lead to inaccurate dose delivery, compromising patient safety and treatment outcomes. ...
Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...
Authors: Dharmin D. Desai, Ellis Lee Johnson, Philip J. Kallenberg, Kapil M. Mishra
Affiliation: Spectrum Medical Physics, University of Kentucky, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: The âAsk For Itâ (AFI) manual optimization strategy has been shown to generate high quality SRS plans within Eclipse. The purpose of this work is to directly compare manually generated Eclips...
Authors: Alexei V. Chvetsov, Pavitra Ramesh, Alexei V. Trofimov
Affiliation: Massachusetts General Hospital, University of Washington
Abstract Preview: Purpose: To investigate the effect of dose and depth dependence of relative biological effectiveness (RBE) on hypofractionated proton therapy for ocular melanoma using equivalent uniform RBE-weighted ...
Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington
Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: To investigate the effect of variation in the α/ÎČ of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study aims to quantify the dose discrepancy associated with improper placement of the Leipzig applicator on the patient's skin.
Methods: Monte Carlo simulations were performed using t...
Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora
Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...
Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...
Authors: Zakaria Aboulbanine, Greeshma A. Agasthya, Paul Inman, Anuj J. Kapadia, Anthony Hong Cheol Lim, Jayasai Ram Rajagopal, Chris C. Wang
Affiliation: Oak Ridge National Laboratory, Georgia Institute of Technology
Abstract Preview: Purpose: Radiobiological simulation via TOPAS-nBio requires significant computational resources and time to provide meaningful results. This study aims to decrease simulation time and computational re...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Gaolong Zhang
Affiliation: Department of Radiation Oncology, School of Physics, Beihang University, School of physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: In intensity-modulated proton therapy (IMPT) for head and neck cancer, CBCT registration ensures accurate setup, minimizing dose errors. Unlike IMRT, IMPT plans directly define tumor volumes ...
Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda
Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina â Gemelli Isola
Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) modelsâdeveloped using Italian breast radiotherapy dataâto a Nepalese hospital, thereby demons...
Authors: Deidre Batchelar, Michael Kudla, Stephanie Merkl, Tony Teke
Affiliation: BC Cancer - Kelowna
Abstract Preview: Purpose: Preplanning 3D-printed templates for cervical and vaginal brachytherapy is an iterative process, often taking hours to for an individual patient.
This study demonstrates an end-to-end auto...
Authors: Lei Ren, Jie Zhang
Affiliation: University of Maryland School of Medicine
Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...
Authors: Jing Cai, Zhi Chen, Hong Ge, Yu-Hua Huang, Bing Li, Zihan Li, Ge Ren
Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital
Abstract Preview: Purpose: Algorithms based on subregional respiratory dynamics (SRD) capture spatiotemporal heterogeneity in the ventilation process, though rely on empirical modelings to map surrogate ventilation. Gi...
Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...
Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Christine Peterson, Paige A. Taylor
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To develop predictive models for IROC SRS head phantom audits and to identify important factors influencing institutional performance.
Methods: The IROC SRS head phantom includes two TLDs ...
Authors: Ameer Elaimy, Theodore Lawrence, Charles S. Mayo, Seyyedeh Azar Oliaei Motlagh, Benjamin S. Rosen
Affiliation: University of Michigan
Abstract Preview: Purpose: To analyze the impact of clinical features on short-term survival, toxicity, and poor outcomes in HCC patients treated with SBRT,using automated data aggregation and enhanced algorithms with ...
Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez
Affiliation: University of Miami
Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...
Authors: Jennifer L. Dolan, Chengyin Li, Parag Parikh, Doris N. Rusu, Kundan S Thind
Affiliation: Henry Ford Health, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The time and resource demands of online Adaptive Radiation Therapy (ART) can limit its widespread clinical adoption and potentially impact patient throughput. To address this, we developed a ...
Authors: Minbin Chen, Ke Lu, Kaizhong Shi, Chunhao Wang, Chuan Wu, Zhenyu Yang, Fang-Fang Yin, Jingtong Zhao
Affiliation: The First People's Hospital of Kunshan, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, Department of Radiation Oncology, Duke Kunshan University
Abstract Preview: Purpose: MRI-based automatic detection of brain metastases is often challenged by the small size and subtle nature of metastases. This study aimed to develop a novel deep learning-based brain metastas...
Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Eric Nguyen, Justin Kyle Pijanowski, Yevgeniy Vinogradskiy
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Thomas Jefferson University
Abstract Preview: Purpose: To enhance a Radiation Oncology departmentâs cyberattack resiliency using a novel software that backs-up critical radiotherapy treatment information. The software returns essential informatio...
Authors: David Chighvinadze, Chieh-Wen Liu, Sugandima Weragoda, Ping Xia
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic
Abstract Preview: Purpose: To explore the feasibility of using coplanar beams with collimator angle optimization for brain SRS plans with Halcyon system.
Methods: This study used a dataset of 26 patients with 2-3 br...
Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda
Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xiâan Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xiâan Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...
Authors: Jadon Buller, Zhuoran Jiang, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of California, Stanford University
Abstract Preview: Purpose: Electroacoustic tomography (EAT) and Protoacoustic (PA) imaging are novel modalities for treatment verification of electroporation and proton therapy. However, the limited acquisition angle i...
Authors: Felicia Chu, Qiongge Li, Jian Liu
Affiliation: Inova Hospital, Brown University Rhode Island Hospital, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
This study aims to enhance the efficiency of stereotactic body radiation therapy (SBRT) planning for lung cancer by developing and evaluating optimization templates derived from historical...
Authors: Yang Lei, Haibo Lin, Tian Liu, Charles B. Simone, Shouyi Wei, Ajay Zheng
Affiliation: Icahn School of Medicine at Mount Sinai, New York Proton Center
Abstract Preview: Purpose: Radiation-induced lung injury (RILI), encompassing pneumonitis and fibrosis, represents a critical dose-limiting factor in lung cancer radiation therapy. Variability in treatment outcomes is ...
Authors: Li Chen, Shouliang Ding, Xiaoyan Huang, Lecheng Jia, Hua Li, Hongdong Liu, Yanfei Liu, Zun Piao, Guangyu Wang
Affiliation: State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Shenzhen United Imaging Research Institute of Innovative Medical Equipment
Abstract Preview: Purpose: Optimal radiotherapy planning is challenging, influenced by anatomical factors such as surrounding organs and tumor characteristics, which complicate dose distribution and target coverage. Wh...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Xinlei Xu, Gaolong Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, School of physics, Beihang University, Beihang University, Department of Radiation Oncology
Abstract Preview: Purpose:
CT simulation is essential for radiation therapy preparation but has limitations in distinguishing lesions. Contrast-enhanced CT (CECT) improves lesion detection and characterization, but ...
Authors: Sarah Burleson, Antonio L. Damato, Yabo Fu, Laura Happersett, Tianfang Li, Xiang Li, Himanshu Nagar, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: An iodinated hydrogel perirectal spacer, injected between the prostate and rectum, reduces rectal high-dose exposure during prostate SBRT. We assessed the feasibility of tracking the spacer a...
Authors: Samira Dabaghmanesh, Beth A. Erickson, William Hall, Jason Hirshberg, An Tai
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Treatment plan evaluation for minimizing duodenal toxicity often involves multiple dose-volume constraints that vary based on fractionation. The Equivalent Uniform Dose (EUD) has emerged as a...
Authors: Angel Gomez, Titania Juang, Grace Gwe-Ya Kim, Boyu Meng
Affiliation: UC San Diego, UCSD, University of California San Diego
Abstract Preview: Purpose: Single-Isocenter Multiple Targets (SIMT) Stereotactic Radiosurgery (SRS) is widely used for its precision and effectiveness. However, standardized quality assurance (QA) protocols for SIMT SR...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...
Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...
Authors: Dean Darnell, Iyanna M Lewis, Francesco Ria, William Paul Segars
Affiliation: Duke University, Duke University Medical Physics Graduate Program, Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University Medical Center
Abstract Preview: Purpose: To estimate radiation dose to pediatric patients during standard CT imaging of the chest and abdomen and determine how dose varies with patient age, height and weight and how measurements com...
Authors: Ramin Abolfath, Alejandro Bertolet, Kofi M. Deh, Rao Khan, Vanessa Sanders, Daniel Suarez-Garcia
Affiliation: Massachusetts General Hospital and Harvard Medical School, University of Sevilla, Brookhaven National Laboratory, Howard University
Abstract Preview: Purpose: To compare the efficacy of 225Ac to 90Y for local cancer therapy by quantifying DNA damage using Monte Carlo simulations.
Methods: The TOPAS n-Bio toolkit was used to simulate the irradiat...
Authors: Christopher G. Ainsley, Pradeep Bhetwal, Yingxuan Chen, Wookjin Choi, Vimal K. Desai, Karen E. Mooney, Adam Mueller, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: MR-guided adaptive radiotherapy (MRgART) has demonstrated improved outcomes for patients with pancreatic cancer. However, the time-consuming re-segmentation of targets and organs-at-risk (OAR...
Authors: Emily Helen Hayes, Chihray Liu
Affiliation: University of Florida
Abstract Preview: Purpose: To evaluate dosimetric discrepancies in bladder dose calculations among rigid, deformed, and manual contouring methods in prostate cancer patients and assess dose variations resulting from bl...
Authors: Brecca Bettcher, Tobey J Betthauser, Bradley T Christian, Sterling Johnson, Lisette LeMerise, Max McLachlan, Andrew McVea, Dhanabalan Murali, Ali Pirasteh, Matthew Zammit
Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center
Abstract Preview: Purpose: The radiotracer [18F]NAV4694 is a desirable alternative to [11C]PiB for measuring amyloid neuropathology related to Alzheimerâs disease (AD), possessing similar imaging characteristics and fa...
Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira
Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio
Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...
Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...
Authors: Alejandro Cuadra, Paulina E. Galavis, Juan Leal, Enrique Lozano, Franklin Reggio, Gabriel Zelada
Affiliation: ClĂnica Iram, Clinica Alemana, Hospital ClĂnico de Magallanes, E&G Medical Systems Ltda, NYU Langone Health
Abstract Preview: Purpose: To investigate and compare the new method âPulse Normalizationâ proposed by Sun Nuclear to correct ion chamber signal for fluctuations in the accelerator output while performing relative dosi...
Authors: Jacob S. Buatti, Kristen A. Duke, Malena Fassnacht, Neil A. Kirby, Parker New, Niko Papanikolaou, Arkajyoti Roy, Yuqing Xia, Michelle de Oliveira
Affiliation: The University of Texas San Antonio, UT Southwestern Medical Center, UT Health San Antonio
Abstract Preview: Purpose:
Quantifying and visualizing uncertainty is critical for building clinical trust in AI-generated dose distributions. This study evaluates Monte Carlo Dropout (MCD), Snapshot Ensemble (SE), ...
Authors: Weiyuan Wang
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose:
This study investigates the variability between popular light meters by measuring mammography review workstation monitors using three calibrated light meters.
Methods:
Three calibrat...
Authors: Rashmi Benda, Qinghao Chen, Shifeng Chen, Giovanni Lasio, Peter Olivieri, Huijun Xu, Junliang Xu, Byong Yong Yi, Baoshe Zhang, Jinghao Zhou
Affiliation: University of Maryland Baltimore Washington Medical Group, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center
Abstract Preview: Purpose:
We investigated if the patients receiving lung stereotactic body radiation therapy (SBRT) have adequate planning target volume (PTV) margins by evaluating the intrafraction motion using a ...
Authors: Yi-Fang Wang, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...
Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang
Affiliation: Cincinnati Children's Proton Therapy Center
Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...
Authors: Hania A. Al-Hallaq, Xuxin Chen, Anees H. Dhabaan, Elahheh (Ella) Salari, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
Radiomics image analysis could lead to the development of predictive signatures and personalized radiotherapy treatments. However, variations in delineation are known to affect hand-crafte...
Authors: Xiaoyu Duan, Xinyu Hu, Runqiu Li, Xiang Li
Affiliation: Dukekunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Accurate detection of small-sized microcalcifications (ΌCalcs) (< 500 ”m) is critical for early breast cancer diagnosis, requiring optimal imaging systems and reconstruction algorithms. Ho...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: DynamicARC is a novel pencil beam scanning (PBS) proton therapy technique with the potential to provide more conformal dose distributions and reduce treatment time. This study investigates th...
Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling
Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...
Authors: Alejandro Bertolet, Mislav BobiÄ, Carlos Huesa-Berral, Aileen O'Shea, Ralph Weissleder
Affiliation: Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a pipeline for estimating the absorbed dose to various organs from positron emission tomography (PET) combined with magnetic resonance imaging (MRI). We use this pipeline to evalua...
Authors: Andrew M Baschnagel, Jonathan W. Engle, Jessica E. Griffin, Gihan Gunaratne, Reinier Hernandez, Randall J Kimple, Aaron M. LeBeau, Natalie Y. Luo, Rachel Minne, Caroline M. Mork, Kwangok P Nickel, Jayden West, Madalynn R. Wopat
Affiliation: University of Wisconsin, University of Wisconsin, Department of Pathology and Laboratory Medicine, Department of Medical Physics, School of Medicine and Public Health, University of WisconsinâMadison, University of Wisconsin - Department of Human Oncology, UW Madison, University of Wisconsin, Department of Medical Physics
Abstract Preview: Purpose: The Mesenchymal-Epithelial Transition gene (MET), a targetable cell surface receptor responsible for stimulating cell growth and proliferation, is altered in approximately 10% of non-small ce...
Authors: Shinichiro Mori, Isabella Pfeiffer, Chester R. Ramsey, Alexander Usynin
Affiliation: Thompson Proton Center, National Institutes for Quantum Science and Technology, Thompson Cancer Survival Center
Abstract Preview: Purpose: Four-dimensional CT imaging (4DCT) has become a standard tool for managing respiratory motion in radiation therapy. However, many treatment delivery systems and most diagnostic CT scanners la...
Authors: Mervat A. Alharbi, Wesley S. Culberson
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Medical Physics Department, School of medicine and Public Health, University of Wisconsin-Madison
Abstract Preview: Purpose: The charge collection using ionization chambers is challenging at ultra-high dose rates (UHDR) due to the high ion recombination The Exradin A30 prototype parallel-plate ion chamber manufactu...
Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao
Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen HospitalïŒ Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...
Authors: Chia-Lung Chien, Wen C. Hsi, Romy Megahed, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
The dosimetric variations induced by inter-fractional anatomical changes in intensity-modulated proton therapy could impact the clinic outcomes for head-and-neck (HN) cancer patients. This...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Darwin Abraham Garcia, Michael P. Grams, Scott C Lester, Maryam Mashayekhi, Douglas John Moseley, Robert W Mutter, Sean S Park, Chrystian Quintero Mateus
Affiliation: Mayo Clinic - Rochester, Mayo Clinic
Abstract Preview: Purpose: MBRT delivers sub-millimeter wide regions of high âpeakâ (~10s Gy) and low âvalleyâ (~1 Gy) doses to treat cancer. MBRT commissioning is performed in flat, uniform plastic water. Thus, differ...
Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga
Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University
Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling, Jianling Yuan
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: To analyze volume changes in the high-risk clinical target volume (HR-CTV) during high-dose rate (HDR) brachytherapy for cervical cancer patients. The study aims to evaluate the trend and cor...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Fan Liu, Adam C. Riegel, Yi-Fang Wang
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, Varian Medical Systems' latest CBCT technology, integrates rapid 6-second data acquisition with advanced iterative reconstruction, enabling precise real-time contouring and dose c...
Authors: Yu-Ying Lin, Yu Chen Shen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...
Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang
Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...
Authors: Emel Calugaru, Jenghwa Chang, Sean T Grace, Nicholas Harvey, Jessica Jung, Ching-Ling Teng
Affiliation: Northwell, Hofstra University, Hofstra University Medical Physics Program
Abstract Preview: Purpose: To evaluate the consistency of MRI distortion corrections across Northwell Health system and evaluate the necessity and importance of distortion QA for MRIs used for stereotactic radiosurgery...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Luuk J Oostveen, Elsa Bifano Pimenta, Ioannis Sechopoulos, Alessandra Tomal
Affiliation: Radboud University Medical Center, University of SĂŁo Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de FĂsica Gleb Wataghin
Abstract Preview: Purpose: This study aimed to evaluate the precision and accuracy of volume measurements for solid nodules (SNs) and ground-glass opacities (GGOs) in lung images acquired using energy-integrating CT (E...
Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...
Authors: Cem Altunbas, Farhang Bayat, Roy Bliley, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose: The use of image features extracted from serial CBCT images to assess radiotherapy response and toxicity is an active research area. However, poor image quality often compromises reliability ...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Jing Feng, Wenzheng Feng, Joseph Hanley, Jeff Stainsby, Tingyu Wang
Affiliation: Synaptive Medical, Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose:
The Synaptive MRI is a 0.5T superconducting head only system (first US install 2023). This is the first study that evaluates the geometric accuracy using a Sun Nuclear MR Distortion and Im...
Authors: Kuan Ling Chen, Jiajin Fan, Maduka M. Kaluarachchi, Wei Nie
Affiliation: Inova Schar Cancer Institute
Abstract Preview: Purpose: This study evaluates the impact of CBCT acquisition speed on the accuracy of moving target alignment during image-guided radiotherapy. Additionally, the influence of target motion speed and r...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Alex T. Price, Sagar Regmi, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To investigate the feasibility and accuracy of using a Hounsfield Unit(HU) calibrated cone-beam computed tomography(CBCT) for direct dose calculation in thoracic treatment settings. In combin...
Authors: Yijian Cao, Jenghwa Chang, Lyu Huang
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systemsâVarianâs TrueBeam (C-arm) and Halcyon (O-ring)âfor prostate Stereotactic Body Ra...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXionÂź X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: To evaluate the potential of a radiation imaging survey meter (RISM) to improve detection and efficiency/speed for radiopharmaceutical therapy (RPT) suite clean up after patient treatment has...
Authors: Christian Fiandra, Marco Fusella, Gianfranco Loi, Silvia Pesente, Lorenzo Placidi, Claudio Vecchi, Orlando Zaccaria, Stefania Zara
Affiliation: Abano Terme Hospital, University of Turin, Maggiore della CaritĂ , Tecnologie Avanzate Srl, Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abstract Preview: Purpose: Deformable-image-registration (DIR) is essential in modern radiotherapy for adaptive RT, re-irradiation, and other clinical applications. Multimodal DIR is especially important in MRI-only wo...
Authors: Chia-Ho Hua, Jirapat Likitlersuang, Jinsoo Uh
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: AI-based fast MRI, which reconstructs images from undersampled k-space data, has not yet been tailored for RT planning. This study aims to evaluate the fast MRI performance of our recently pr...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Arjit K. Baghwala, Devin J. Olek, Parth K. Patel, Ramiro Pino, Adam Yanez
Affiliation: Houston Methodist Hospital, Kaiser Permanente
Abstract Preview: Purpose: The Halcyon beam model in Eclipse is immutable and only includes output factors (OF) for fields down to 1x1 cm2. The TPS must extrapolate OFs for smaller fields used in stereotactic (SRS/SBRT...
Authors: Julie Colnot, Eric Deutsch, Christelle Huet, Danahé LeBlanc, Pauline Maury, Charlotte Robert, Imane Saïd Mansour, Cathyanne Schott, Francois Therriault-Proulx
Affiliation: INSERM U1030, Gustave Roussy, University Paris-Saclay, LDRI, IRSN, Medscint, THERYQ / INSERM U1030, Gustave Roussy, University Paris-Saclay, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique
Abstract Preview: Purpose: FLASH radiotherapy, using ultra-high dose rates (UHDR, >100 Gy/s), spares healthy tissues while maintaining tumor control compared to conventional radiotherapy (CONV). However, UHDR dosimetry...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To systematically evaluate the relationship between Activity Concentration (AC) obtained from the RefleXion PET-Linac with the maximum standardized uptake value (SUVmax) derived from a diagno...
Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC
Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyonâs doub...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Our GammaKnife(GK) has been upgraded from 4C to ICON recently. In this study we evaluated the performance of Lightning IPO for ICON.
Methods: 10 cases with single brain metastasis previous...
Authors: Milad BaradaranGhahfarokhi, Ashley Elizabeth Bonner, James R. Burns, Annie Cooney, George X. Ding, Kenneth L. Homann, Guozhen Luo
Affiliation: Corewell Health William Beaumont University Hospital, Vanderbilt University Medical Center
Abstract Preview: Purpose: The goal of this study was to evaluate the performance of a new plastic scintillating detector (PSD) system with 0.5Ă0.5 mm2 and 1.0Ă1.0 mm2 probes (referred to as Medscint0.5 and Medscint1.0...
Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu
Affiliation: Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: In August 2024, ZAP-X introduced automatic placement for isocenters in a DP-1010 upgrade for treatment planning. In this study, plans made by automatic placed isocenters are compared to those...
Authors: Gweneth Andersen, Colleen M. Foote, David (Bo) McClatchy, Hannah McFarland
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantify the impact of MLC model differences and LINAC age on treatment plan evaluation by log file-based patient-specific QA (PSQA) through the lifetime of the machines.
Methods: 3D ga...
Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding
Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington
Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...
Authors: Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Yin Gao, Xun Jia, Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Johns Hopkins University
Abstract Preview: Purpose: Understanding how physicians evaluate plans is critical for automatic planning and ensuring consistent, high-quality care. While deep-learning models excel in complex decision-making, the lac...
Authors: Adnan Jafar, Xun Jia, Michael B. Roumeliotis
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: HDR brachytherapy (HDRBT) treatment planning is challenging due to the need for high-quality plans under time pressure, considering anatomy and applicator geometry. This study proposes an exp...
Authors: Daisuke Kawahara, Yoichi Watanabe
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School
Abstract Preview: Purpose: To theoretically demonstrate that FLASH dose delivery leads to higher normal tissue sparing than conventional dose rates.
Methods: A two-component kinetic model was built for target and da...
Authors: José Antonio Klautau Toffoli, Anthony G. Tessier, Atiyah Yahya
Affiliation: Department of Oncology, University of Alberta
Abstract Preview: Purpose: To demonstrate that magnetic resonance spectroscopy (MRS) methyl (â0.9 ppm) to glycerol (â4.1-4.3 ppm) resonance area ratios correlate with relative concentrations of free fatty acids to trig...
Authors: Nobuki Imano, Daisuke Kawahara, Misato Kishi, Yuji Murakami
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University
Abstract Preview: Purpose: This study aims to develop a comprehensive Multi-score by integrating Radiomics-score (Rad-score), Gene-score derived from gene expression levels, and tumor environment Rad-score (TE-Rad-scor...
Authors: Oi-Wai Chau, Beata Gontova Bernat, Mary Gronberg, Yao Hao, Amanda M. Jackson, Nupur Karmaker, Dishane Chand Luximon, Osama R. Mawlawi, Ikechi Samuel Ozoemelam, Deepak Shrestha, William Swanson, Md Tofiz Uddin, Joseph Weygand, Afua A. Yorke
Affiliation: University of Michigan, Mayo Clinic, Champion Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Washington University in St Louis, Washington University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, National Institute of Cancer Research and Hospital, Emory University, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To evaluate perception and awareness of global medical physics (GMP) as a career path among medical physics professionals and trainees, identify opportunities to enhance professional developm...
Authors: Caiden Atienza, Pim T. S. Borman, Martin F. Fast, Daniel E. Hyer, Bas W. Raaymakers, Jeffrey E. Snyder, Prescilla Uijtewaal, Peter Woodhead
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Yale New Haven Health, University of Iowa
Abstract Preview: Purpose:
On conventional C-arm linacs, VMAT is the preferred delivery modality due to its superior efficiency and highly conformal dose distributions. MR-linacs offer superior soft-tissue imaging t...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To compute effective doses associated with imaging of the extremities with a HiRise (CurveBeam AI, Hatfield, PA) cone-beam CBCT scanner specifically designed for weight-bearing imaging of the...
Authors: Samuel L. Brady, Joseph G. Meier, Elanchezhian Somasundaram, Andrew T Trout
Affiliation: Cincinnati Children's Hospital Medical Ctr, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To analyze eye-tracker gaze data for insights into radiologistsâ areas of focus in an observer study of whole-body PET images.
Methods:
For a comparative study of dose matched PET im...
Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis
Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer
Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)
Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...
Authors: Justus Adamson, Wesley Andrew Cunningham, Chang-Sei Kim, Yeongoh Ko
Affiliation: Duke University, Chonnam National University, Duke University Medical Center
Abstract Preview: Purpose: Toxicity to bowel remains a challenge for radiotherapy, particularly for abdominal SBRT . We propose a noninvasive method to reposition bowel using a remote magnetic navigation system (RMNS) ...
Authors: Miguel Albaladejo, Ana Corbalan, Aitor Ortega, Vicente Puchades, David Ramos, Alfredo Serna-Berna, Jonattan Suarez
Affiliation: Hospital General Universitario Santa Lucia
Abstract Preview: Purpose:
Prostate SBRT treatments are frequently delivered using standard VMAT IGRT technique. The aim of this study is to test the feasibility of Ethos Artificial Intelligence (AI) prostate SBRT b...
Authors: Anthony Hong Cheol Lim, Rayyan L Mahmood, Alexander Stanforth, Chris C. Wang, Mingyao Zhu
Affiliation: Georgia Institute of Technology, Emory University
Abstract Preview: Purpose: The purpose of this project is to test the feasibility of proton minibeam lattice radiotherapy within an existing clinical setting.
Methods:
The TOPAS code is used to model a scenario i...
Authors: Denis Bergeron, Larry A. DeWerd, Sean Jollota, Peyton Alexandra Lalain, Likhitha Polepalli
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, National Institute of Standards and Technology
Abstract Preview: Purpose: 90Y is a challenging radionuclide to measure because it is a pure beta-emitter and is typically quantified using a radionuclide calibrator. These devices, such as the Capintec model used in t...
Authors: Grace Hutchinson, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: To assess the feasibility and consistency of the Sun Nuclear Corporation (SNC) MR conditional Quad Wedge, as an accessory to the IC Profiler-MR, and to evaluate beam output and energy in the ...
Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...
Authors: Jochen Cammin, Shifeng Chen, Arun Gopal, Kai Huang, Jason K Molitoris, Amit Sawant, Kai Wang
Affiliation: University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: The HyperSight CBCT optional feature on Varian TrueBeam linacs offers a larger field-of-view, improved Hounsfield units (HU) accuracy, and overall improved image quality, including metal arti...
Authors: Melissa Bronson, Elizabeth L. Covington, Robert T. Dess, Joseph R. Evans, William C. Jackson, Charles S. Mayo, Michelle L. Mierzwa, Benjamin S. Rosen, VG Vinod Vydiswaran, Grant Weyburne, Zheng Zhang, Henry Zocher
Affiliation: PCORnetÂź, The National Patient-Centered Clinical Research Network, University of Michigan
Abstract Preview: Purpose: Diagnosis and staging are an integral part of cancer care, but this information is often scattered across various electronic medical records. The fragmentation increases overall documentation...
Authors: Yiran Liu, Zhengzheng Liu, Fang-Fang Yin
Affiliation: Duke Kunshan Univeristy, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: To investigate the feasibility of producing high dose rate GRID therapy using a compact linear accelerator (LINAC) treatment head with scanning beam and stationary grid collimator.
Methods...
Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...
Authors: Sung Hwan Ahn, Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, Hyeongjin Lim, Sang Yoon PARK, Myonggeun Yoon
Affiliation: Institute of Global Health Technology (IGHT), Korea University, Republic of Korea, Korea University, Samsung Medical Center
Abstract Preview: Purpose:
This study aims to evaluate the feasibility of real-time monitoring of conductivity changes induced by thermal variations during tumor treating fields (TTFields) therapy using Electrical I...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Renan Felix dos Santos, Gustavo Freire Pereira da Silva, Alessandra Tomal
Affiliation: University of SĂŁo Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de FĂsica Gleb Wataghin
Abstract Preview: Purpose: Evaluate the feasibility of a bench-top PCCT using Geant4 Monte Carlo simulations. The study applied the Geant4 framework on determining the electronic density of materials as a function of C...
Authors: Xinyuan Chen, Geoffrey D. Hugo, Alex T. Price, Pamela Samson, Tianyu Zhao
Affiliation: University Hospitals Seidman Cancer Center, University of South Florida, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Xinyuan Chen
Affiliation: Washington University School of Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Resat Aydin, Joseph Barbiere, Brett Lewis, Roland Teboh
Affiliation: HUMC, Hackensack University Medical Center
Abstract Preview: Purpose:
Accurately compensating for respiratory-induced tumor motion is critical in BgRT, where precise delineation of volumes ensures effective dose delivery. We propose an integrated approach th...
Authors: Robert Berry, John Buatti, Nathan Burger, Ryan T. Flynn, Greg Johns, Maksim Kravchenko, Sergey Kutsaev, Yen-Po Lee, Marcos Ruelas, Joel J. St-Aubin, Timothy J. Waldron
Affiliation: RadiaBeam Technologies, University of Iowa
Abstract Preview: Purpose: To report the factory acceptance tests of a preclinical linear accelerator, the FLEX-9 electron FLASH linac from RadiaBeam Technologies.
Methods: The FLEX-9 FLASH electron linac is designe...
Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers SĂžrensen, Matthias WĂŒrl
Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam
Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.
Methods:...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study introduces a novel template-guided deep learning framework for primary gross tumor volume (GTVp) segmentation, addressing challenges posed by diverse tumor types and enabling a uni...
Authors: Xianjin Dai, PhD, Michael Gensheimer, Praveenbalaji Rajendran, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: Recent advances in the automatic delineation of radiotherapy treatment targets, which incorporate linguistic clinical data extracted by large language models (LLMs) into traditional visual-on...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon
Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester
Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...
Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of WisconsinâMadison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison
Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...
Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner
Affiliation: HarvardâMIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin
Affiliation: Labaid Cancer Hospital & Superspeciality Centre
Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...
Authors: Prabhu C. Acharya, Hassan Bagher-Ebadian, Stephen L. Brown, James R. Ewing, Mohammad M. Ghassemi, Benjamin Movsas, Farzan Siddiqui, Kundan S Thind
Affiliation: Michigan State University, Oakland University, Henry Ford Health
Abstract Preview: Purpose: Accurate T1 quantification using T One by Multiple Read Out Pulse (TOMROP) sequences is essential for physiological assessments in dynamic-contrast-enhanced (DCE) MRI and T1 mapping studies. ...
Authors: Kenneth L. Homann, Natalie A Lockney, Hong Zhang
Affiliation: Department of Radiation Oncology, Vanderbilt University Medical Center, Vanderbilt University Medical Center
Abstract Preview: Purpose: The aim of this study is to develop a treatment planning methodology utilizing liver functional imaging via contrast-enhanced Magnetic Resonance Imaging (MRI) in patients undergoing stereotac...
Authors: Bingqi Guo, Ping Xia
Affiliation: Cleveland Clinic
Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a âGRIDâ or âlatticeâ of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...
Authors: Dirk A Bartkoski, Michael Kleckner, Dongyeon Lee, Reza Reiazi, Mohammad Reza Salehpour
Affiliation: The University of Texas MD Anderson Cancer Center, Convergent-RnR
Abstract Preview: Purpose:
To develop and validate G4BraggReflection, a novel physics process within Geant4, designed to incorporate diffraction properties resulting in Bragg reflection into Monte Carlo simulations....
Authors: Veng Jean Heng, Jan P. Seuntjens, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, Stanford University, Princess Margaret Cancer Centre & University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: We have developed a GPU-accelerated Monte Carlo (MC) simulation to determine the cumulative dose distribution of patients undergoing Total Skin Electron Therapy (TSET) using the Stanford tech...
Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu
Affiliation: Massachusetts General Hospital, MGH
Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...
Authors: Hamid Abdollahi Nasehabad, Mehrangiz Amiri, Mohammad Reza Deevband, Faraz Kalantari, Milad Peer-Firozjaei, Ali Shabestani Monfared, Ehsan Tajikmansoury
Affiliation: Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Department of Radiology, University of British Columbia, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, 1. Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine
Abstract Preview: Purpose:
Targeted radionuclide therapy (TRNT) with 213Bi- labeled radiopharmaceuticals is a promising approach in targeted alpha and beta therapy for cancer. This study aims to assess double-strand...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...
Authors: Jianrong Dai, Jun Dang, Enzhuo Quan, Yong Sang, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center / National Clinical Research Center for Cancer / Cancer Hospital & Shenzhen Hospital / Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: The current conformity index (CI) formula is distorted for radiotherapy plans with multiple, non-enclosing targets. We redefined the volume of reference isodose (VTV) parameter in the CI form...
Authors: Ming Chao, Karyn A Goodman, Yang Lei, Tian Liu, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for motion management in MRI-guided radiotherapy (MRIgRT), yet acquiring high-quality 3D images remains challenging due to time constraints and motion ar...
Authors: Pouya Azarbar, Nima Kasraie, Mahsa Shahrbabki Mofrad, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences, Tehran University of Medical Science
Abstract Preview: Purpose: PET imaging become crucial in diagnosing and managing various diseases, but its key limitation is the lack of detailed anatomical information. Integrating CT-scans with PET images enhances cl...
Authors: Pouya Azarbar, Nima Kasraie, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose: Positron Emission Tomography (PET) is crucial for diagnosing and monitoring diseases due to its functional imaging capabilities. However, its high cost, significant radiation exposure, and li...
Authors: Seth Amofa, Erli Chen, Samuel A. Einstein, Ekinadoese Imudia Frias, Nupur Karmaker, Yinus Kawthara, Dulguun Myagmarsuren, Travis C. Salzillo, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Federal University Oye-Ekiti, Cheshire Medical Center, Dartmouth College, Penn State College of Medicine, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Virginia Tech Carilion School of Medicine
Abstract Preview: Purpose: Recent developments in the medical physics job market have made it increasingly difficult for radiotherapy centers, particularly in rural areas, to recruit qualified therapeutic medical physi...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...
Authors: Oluyemi Bright Aboyewa, KyungPyo Hong, Daniel Kim
Affiliation: Department of Radiology, Northwestern University
Abstract Preview: Purpose: While non-Cartesian MRI is desirable for fast imaging with high spatial resolution and robustness to motion, it requires long post-processing times. Preconditioning with an adequate density c...
Authors: Stephen M. Avery, Izabella L. Barreto, Oi-Wai Chau, Cesar Della Biancia, Beata Gontova Bernat, Amanda M. Jackson, Rao Khan, Eugene P. Lief, Osama R. Mawlawi, Wilfred F. Ngwa, Christopher F. Njeh, Peter Allan Sandwall, William Swanson, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, VA Medical Center, Johns Hopkins University, Mayo Clinic, Champion Cancer Center, Howard University, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, University of Florida College of Medicine, Washington University in St Louis, Emory University, University of Pennsylvania, OhioHealth, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: To assess needs of medical physicists working in low-and-middle-income countries (LMICs)
Methods: A survey was developed by AAPMâs Global Needs Assessment Committee (GNAC) in partnership w...
Authors: Enhui Chang, Yunfei Dong, Yifei Hao, Chengliang Jin, Shengsheng Lai, Yi Long, Mengni Wu, Yulu Wu, Ruimeng Yang, Zhenyu Yang, Yue Yuan, Lei Zhang, Wanli Zhang, Yaogong Zhang
Affiliation: Duke Kunshan University, Department of Radiology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Macrotrabecular-Massive Hepatocellular Carcinoma (MTM-HCC) is one type of liver cancer showed minimum image signature for accurate non-invasive diagnosis. This study aims to develop and evalu...
Authors: Daria Gaykalova, Ranee Mehra, Jason K Molitoris, Hajar Moradmand, Lei Ren, Amit Sawant, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Maryland University Baltimore, University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: Radiomics extracts quantitative imaging biomarkers from medical images. However, maintaining the reproducibility and stability of selected features across institutions and parameter settings ...
Authors: Ashley Cetnar, Emily Y. Hirata, Cassandra Stambaugh
Affiliation: University of California San Francisco, Tufts Medical Center, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: To provide results from the first four years of the Medical Physics Leadership Academy (MPLA) Fundamental of Leadership Cohort program
Methods: The MPLA Cohorts program began with the Fund...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: Fitria P Krisna, Mardon Limena, Supriyanto Ardjo Pawiro, Jhon H Saragih, Wahyu E. Wibowo, Poonam Yadav, Ummu M Zahro
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Radiation Oncology Dr. Cipto Mangunkusumo National Central Public Hospital, Department of Physics, Mathematics and Natural Sciences, University of Indonesia, Department of Radiotherapy, Mandaya Hospital, Department of Radiation Oncology, Mitra Keluarga Kenjeran Hospital, Department of Radiotherapy, Mandaya Royal Hospital, Radiation Oncology, Santosa Hospital
Abstract Preview: Purpose: To perform depth dose characteristics of High Dose Electron Beam and utility of various commercially available detectors.
Methods: The measurements were performed using an Elekta Versa HD ...
Authors: Cheng-Chieh Cheng, Jeffrey P Guenette, Yajun Li, Bruno Madore, Lei Qin
Affiliation: Brigham and Women's Hospital, National Sun Yat-sen University, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Pilot tone (PT), a compact RF sensor, has been integrated into clinical practice for motion detection. Prior studies proposed mapping PT signals to head positions using a calibration step tha...
Authors: Davide Brivio, Lia Carroll, Juliane Daartz, Jan PO Schuemann, Piotr Zygmanski
Affiliation: Massachusetts General Hospital, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: We employ High-Energy Current (HEC) detectors for real-time monitoring of proton beams at conventional to FLASH dose rates. This would help overcome the need for fast and accurate dosimeters ...
Authors: B. Gino Fallone, Alireza Gazor, Andrei D. Ghila, Gawon Han, Patricia A. K. Oliver, Michael W. Reynolds, Keith D. Wachowicz, Tania Rosalia Wood, Shima Y. Tari, Eugene Yip
Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Nova Scotia Health, Dept. of Medical Physics and Dalhousie University, Dept. of Physics and Atmospheric Science, Dept. of Radiation Oncology, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com, Department of Medical Physics, Arthur J. E. Child Comprehensive Cancer Centre, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Department of Medical Physics, BC Cancer, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute
Abstract Preview: Purpose: To develop and validate a high-fidelity Monte-Carlo (MC) model of a 0.5T bi-planar Linac-MR in TOPAS, focusing on accurate Multileaf Collimator (MLC) modelling and positioning for open apertu...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: Adnan Jafar, Xun Jia, An Qin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose: 3D whole-brain radiotherapy (WBRT) is widely used due to its simplicity and effectiveness. While modern treatment planning systems, like RayStation, offer automated Field-in-Field planning, p...
Authors: Rex A. Cardan, Carlos E. Cardenas, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li, Rodney J. Sullivan, Natalie N. Viscariello, Christopher Willey
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: vBrain radiosurgery toxicity-rate is estimated via clinically-relevant isodose volume (IDV) thresholds according to HyTEC (e.g., V12Gyâ€10cc). HyperArcTM (HA) automated planning allows accurat...
Authors: Beverly Allen, Jay C. Buckey, David J. Gladstone, P. Jack Hoopes, David I Hunter, Armin Tavakkoli
Affiliation: Thayer School of Engineering, Dartmouth College, Geisel School of Medicine, Dartmouth College, Geisel School of Medicine, Thayer School of Engineering
Abstract Preview: Purpose: Hyperbaric oxygen (HBO) therapy immediately prior to radiation therapy has been proposed as treatment to enhance radiosensitivity of hypoxic tumors. A murine glioblastoma model was utilized t...
Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan
Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health
Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: Mark Ashamalla, Renee Farrell, Jinkoo Kim, Kartik Mani, Xin Qian, Samuel Ryu, Yizhou Zhao
Affiliation: Stony Brook Medicine, Stony Brook University Hospital
Abstract Preview: Purpose: Adaptive planning is increasingly used in head and neck radiation therapy due to factors like tumor response or changes in patient anatomy. However, methods such as resimulation or offline re...
Authors: Ryan Andosca, Peter Boyle, Grace Hyun Kim, Minji Victoria Kim, Michael Vincent Lauria, Michael F. McNitt-Gray, Gabriel Melendez-Corres, Jack Neylon, Brad Stiehl, Pang Yu Teng
Affiliation: David Geffen School of Medicine at UCLA, University of California, Los Angeles, UCLA Department of Radiology, Department of Radiation Oncology, University of California, Los Angeles, UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Endobronchial Valves (EBV) are one of the few treatment options for patients with moderate to severe emphysema. Eligibility is typically assessed from CT image data analysis including Emphyse...
Authors: Christina Brunnquell, Diana Elizabeth Carver, Jaydev K. Dave, Hadley Anna DeBrosse, Hannah Grover, Andrew M. Hernandez, Youngkyoo Jung, Megan E. Lipford, Kevin J. Little
Affiliation: Wake Forest University School of Medicine, Oregon Health & Science University, University of California, Mayo Clinic, The Ohio State University, Vanderbilt University Medical Center, University of Minnesota
Abstract Preview: Purpose: Medical imaging physicists play a crucial role in ensuring patient safety, overseeing quality control (QC) of imaging systems, and enhancing diagnostic accuracy. Medical imaging physicists ha...
Authors: James M. Lamb, Dishane Chand Luximon, Jack Neylon, Rachel Petragallo, Moritz Ritter, Timothy Ritter
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, ETH Zurich, VCU Health System, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: Anomalies in cone beam computed tomography (CBCT) radiotherapy image guidance can signal treatment deviations. Repetitive review of setup image registrations by humans is inefficient, prone t...
Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu
Affiliation: Willis Knighton Cancer Center
Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...
Authors: John M. Boone, Andrew M. Hernandez, Paul E. Kinahan, Michael F. McNitt-Gray, Jeffrey H. Siewerdsen, Ali Uneri
Affiliation: University of California, Johns Hopkins Univ, UT MD Anderson Cancer Center, David Geffen School of Medicine at UCLA, University of Washington, UC Davis Health
Abstract Preview: Purpose: Measuring image quality (IQ) in large clinical databases, such as the Medical Imaging and Data Resource Center (MIDRC), is challenging due to the inherent complexity of image content and the ...
Authors: John Ginn, Chenlu Qin, Deshan Yang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: Clinical implementation of auto-segmentation tools has been hindered by poor interpretability and generalizability of AI models, necessitating the development of automated contour quality ass...
Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan
Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem
Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...
Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc LaperriÚre, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Analogic Canada
Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...
Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...
Authors: Ning Cao, Sunan Cui, Danielle P. Johnson Erickson, Juergen Meyer, Ramesh Rengan, Ben A Shaver, Jing Zeng
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To investigate the immune response in primary irradiated tumors and non-irradiated tumors in a mouse melanoma xenograft model, comparing 18Gy of conventional (CONV) and ultra-high dose rate (...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...
Authors: William P. Donahue, Lauren Smith, Shu (Stella) Xing
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To quantify the dosimetric uncertainty of end-exhale gating as a function of breathing pattern.
Methods: A Truebeam delivered AP square fields to EBT4 film placed in the Quasar MRI4D M...
Authors: Samuel L. Brady, Joseph G. Meier
Affiliation: Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...
Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink
Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University
Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...
Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...
Authors: Michael Ashenafi, Nicholas Becerra Espinosa, Mario Ramos Gallardo, Matthew Pacella, Sean M. Tanny
Affiliation: Department of Radiation Oncology, University of Rochester
Abstract Preview: Purpose: A new multileaf collimator (MLC) model has been introduced in Varian Eclipse v18.0, with the treatment planning system (TPS) explicitly modeling the leaf end effects. The vendor recommends a ...
Authors: Mylinh Dang, Indra J. Das, George X. Ding, Ahtesham Ullah U Khan, Andrew J. White
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine, Vanderbilt University Medical Center
Abstract Preview: Purpose: The large variability in field output factor (FOF) observed among various studies is speculated to be due to uncertainty in jaw reproducibility that is linked directly with source occlusion. ...
Authors: David Chighvinadze, Indra J. Das, Jeremy D. Donaghue, Kevin Stephans, Gregory Videtic, Sugandima Weragoda, Ping Xia
Affiliation: Cleveland Clinic, Cleveland Clinic Sandusky, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Cleveland Clinic Fairview
Abstract Preview: Purpose:: Evaluate the impact of lung density variations on plan quality and delivery parameters in lung SBRT Plans.
Methods: For a hypothetical case with a real patient anatomy, three GTVs with vo...
Authors: Maria Jose Almada, Oscar Apaza, Carlos Bohorquez, Ezequiel Cabrera, Rogelio Diaz Moreno, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, FaMAF, UNC, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA employs gamma analysis to verify the planned versus delivered dose. Evaluating the effectiveness of PSQA techniques in identifying errors is crucial. This study aims to incorporate ML...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Amrit Kaphle
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To assess the effectiveness of various nanoscale models of gold nanoparticle (GNP)-laden cells for Monte Carlo (MC) studies of GNP-mediated radiation dose enhancement/DNA damage.
Metho...
Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou
Affiliation: University of Kentucky, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...
Authors: Wesley S. Culberson, Larry A. DeWerd, Ahtesham Ullah Khan, Zachary James Welchel
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Flattening filter free (FFF) linac beams exhibit a centrally peaked beam profile due to the forward-directed bremsstrahlung production from MeV electrons, leading to volume averaging effects ...
Authors: Mauricio Acosta, Zachary Fellows, Alonso N. Gutierrez, Noah S. Kalman, Kristen A. McConnell, Rob Rohe, Andrew J. Wroe, Sreenija A Yarlagadda
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Beam selection is crucial in proton therapy to ensure optimal physical and biological dose conformity to the target while maximizing sparing of normal tissue. This work investigates the im...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu, Chi To Yung
Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose:
The Elekta Unity system facilitates daily adaptive radiotherapy using MRI-based treatment planning. However, MR images are prone to motion artefacts caused by respiratory motion, potential...
Authors: Anupama Chundury, Hyejoo Kang, John C. Roeske, Iris A. Rusu
Affiliation: Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose: To quantify the dosimetric impact of six degrees of freedom (6DoF) intrafractional errors on gross tumor volume (GTV) and planning target volumes (PTV) for single-isocenter multi-target stere...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Spencer Behr, Joseph Grudzinski, Youngho Seo, Jaehoon Shin, Yiran Wang, Frederick J. Wilson
Affiliation: University of California San Francisco, University of California, San Francisco, Voximetry, Inc., Voximetry, Inc
Abstract Preview: Purpose: Voxel-level imaging-based dosimetry enables a significant improvement in accurate and personalized treatment planning in radiopharmaceutical therapy, potentially leading to optimized disease ...
Authors: Xiangli Cui, Wei Han, Jie Li, Lingling Liu
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences
Abstract Preview: Purpose: To investigate the influence of tissue heterogeneity on proton beam linear energy transfer (LET) and relative biological effectiveness (RBE) using nine RBE models. This study quantifies the i...
Authors: Marissa Brown, Geoffrey D. Clarke, Luke Norton
Affiliation: University of Texas Health Science Center at San Antonio
Abstract Preview: Purpose: To evaluate how different learning strategies affect convolutional neural network (CNN) estimates of the liver's intravoxel incoherent motion (IVIM) parameters.
Methods: A 3-stage U-Net wa...
Authors: Jacqueline M. Andreozzi, Savannah Decker, Diego Hernandez, Iman R. Washington
Affiliation: UC San Diego, Department of Radiation Oncology, Moffitt Cancer Center, University of South Florida, Moffitt Cancer Center
Abstract Preview: Purpose: Recent advances in external beam radiation therapy have begun to explore the utility of Cherenkov radiation imaging as a beam delivery visualization tool. When sheet bolus is used during trea...
Authors: Jason Chiang, Magnus Dahlbom, Veronica Hankil, Xinyi Li, Catherine (Caffi) Meyer, Kyung Hyun Sung
Affiliation: UCLA, University of California, Los Angeles
Abstract Preview: Purpose:
Yttrium-90 (90Y) radioembolization is a well-established therapy for large or multifocal liver tumors. Accurate dosimetry is critical but remains challenging, as low particle density risks...
Authors: Samuel L. Brady, Kevin Chen, Joseph G. Meier
Affiliation: University of Cincinnati, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose: Conebeam-CT (CBCT) acquisition protocols typically do not distinguish between adults and pediatrics. In collaboration with a fluoroscopically-guided interventional (FGI) manufacturer, new, do...
Authors: Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant
Affiliation: Fuse Oncology, Cone Health
Abstract Preview: Purpose: The Joint Commission (JC) mandates that healthcare organizations establish and evaluate staff competencies to ensure safe and effective patient care. In the context of increasing sub-speciali...
Authors: Andreea Dimofte, Maksym Sharma, Weibing Yang, Timothy C. Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose:
To assess the effectiveness and dosimetric impact of utilizing a knowledge-based planning model for GI site-specific plans.
Methods:
Six knowledge-based planning models were develope...
Authors: Ibtisam Almajnooni, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: We developed a deep learning neural network (DLNN) to predict the risk of radiation-induced esophagitis (RE) during lung cancer radiation therapy based on the spatial dose distribution, for t...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock
Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research
Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...
Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka
Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: Proton therapy plans can be highly sensitive to both anatomical changes and positional errors, making the acquisition of Quality Assurance CT (QACT) images a routine clinical practice during ...
Authors: Evan Calabrese, Scott R. Floyd, Kyle J. Lafata, Zachary J. Reitman, Eugene Vaios, Chunhao Wang, Lana Wang, Deshan Yang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University
Abstract Preview: Purpose:
This study proposes a novel neural ordinary differential equation (NODE) framework to distinguish post-SRS radionecrosis from recurrence in brain metastases (BMs). By integrating imaging f...
Authors: Krishnendu Saha
Affiliation: Cleveland Clinic Foundation
Abstract Preview: Purpose: The goal is to improve quantitative accuracy of a Maximum-a-posteriori expectation maximization (MAPEM) reconstruction of SPECT phantom images by optimizing Gibbs prior parameters.
Methods...
Authors: Clifford Eskey, Scott Gordon-Wylie, Scott Gordon-Wylie, Dhrubo Jyoti, Daniel Reeves, John B. Weaver
Affiliation: Flow Aluminum, Dartmouth College, Fred Hutch Cancer Center, University of Washington, Dartmouth-Health
Abstract Preview: Purpose: Mechanical thrombectomy (MT) is the preferred treatment for ischemic stroke from large vessel occlusion. The thrombus or clot is extracted from the vessel via a catheter using a stent retriev...
Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte
Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine
Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...
Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Dylan Mather, Akira Nishikori, Daniel W Shin
Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA
Abstract Preview: Purpose: To validate the performance a deep learning reconstruction (DLR) algorithm in an anatomical background compared to a uniform phantom background.
Methods: An analytic forward projection mod...
Authors: Davide Brivio, Erno Sajo, Ryan Williams, Piotr Zygmanski
Affiliation: University of Massachusetts Lowell, Brigham and Women's Hospital, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a non-invasive 3D in-vivo dosimetry tool exploring the relationship between positron annihilations and dose per voxel using Monte Carlo simulation. The Positron Guided Radiation Th...
Authors: Alexander Alsalihi, Gary Y. Ge, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: The upcoming CMS regulation, titled âExcessive Radiation Dose or Inadequate Image Quality for Diagnostic Computed Tomography (CT) in Adultsâ, employs two measures, size-adjusted DLP (SAD) and...
Authors: Marwa Y. Abdel Tawwab, Amin E Amin, Abdullah M. ElSharif, Somaia Metwally Elsayed, Magdy M. Khalil
Affiliation: School of Applied Health Science, Badr University in Cairo (BUC), Cairo, Egypt, Medical Physics, Radiation Oncology Department, Faculty of Medicine, Ain Shams University, Medical Biophysics, Department of Physics, Faculty of Science, Helwan University
Abstract Preview: Purpose: Prostate cancer radiotherapy typically employs conventional fractionation schedules over approximately eight weeks. This study investigates the effect of variations in the α/ÎČ ratio on dose c...
Authors: Scott James Bright, Hadil Elldakli, Mojtaba Hoseini-Ghahfarokhi, Rishab Kolachina, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Gabriel O. Sawakuchi, Walison Augusto Silva Brito, Mark Wasley
Affiliation: MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center, Medical College of Georgia
Abstract Preview: Purpose:
Glutaminase 1 (GLS1) is an intracellular enzyme crucial for generating antioxidants such as glutathione (GSH). GSH neutralizes reactive oxygen species (ROS) induced by radiotherapy. About ...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-”m tungsten wire was imaged at ...
Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam
Affiliation: University of Michigan
Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...
Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...
Authors: Mohammadreza Ay, Nahal Daneshgar, Nima Kasraie, Abbas Monsef, Zeinab Peymani, Hadi Rezaei, Peyman Sheikhzadeh
Affiliation: University of Minnesota Medical School, Radiation Oncology, Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Shiraz University of Medical Sciences, Department of Medical Physics, Tehran University of Medical Sciences, Department of Medical Physics and Biomedical Engineering, UT Southwestern Medical Center, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose:
This study aims to design and simulate an innovative pediatric-dedicated SPECT scanner optimized for childrenâs unique anatomical and safety needs by enhancing sensitivity in data acquisit...
Authors: Salim Balik, Nguyen Phuong Dang, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: An accurate and convenient monitoring of radiation dose delivery during treatment is essential for ensuring patient safety and treatment efficacy. This project aims to develop innovative algo...
Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose:
MR-guided adaptive radiation therapy (MRgART) is transforming clinical workflows, requiring fast, accurate organs-at-risk (OARs) contouring. While deep learning auto-segmentation (DLAS) of...
Authors: Manuel M. Arreola, Izabella L. Barreto, Amanda Schwarz
Affiliation: University of Florida, University of Florida College of Medicine
Abstract Preview: Purpose: In 2020, a medical physics undergraduate internship program was developed to attract competitive students to the field of medical physics.
Methods: The program offered a unique, immersive ...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Pretesh Patel, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study aims to improve organ-at-risk (OAR) segmentation in pancreatic cancer stereotactic body radiotherapy (SBRT) by integrating clinical guidelines into deep learning workflows. We use ...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: Xuezhen Feng, Li-Sheng Geng, Haoze Li, Xi Liu, Tianyu Xiong, Ruijie Yang
Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, School of Physics, Beihang University, School of Nuclear Science and Technology, University of South China, Department of Radiation Oncology, Peking University Third Hospital
Abstract Preview: Purpose: This study aimed to develop a deep learning-based algorithm for automatically delineate gross tumor volume (GTV) for lung cancer patients, alleviating the workload of radiologists and improvi...
Authors: Jue Jiang, Aneesh Rangnekar, Shiqin Tan, Harini Veeraraghavan
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences
Abstract Preview: Purpose: Clinicians often use information from FDG-PET and CT to interpret and delineate gross tumor (GTVp) and nodal (GTVn) volumes for radiotherapy planning in head and neck (HN) cancer patients. He...
Authors: Ali Ajdari, Thomas R. Bortfeld, Christopher Bridge, Gregory Buti, Marcela Giovenco, Fredrik Lofman, Gregory C. Sharp, Helen A Shih, Tugba Yilmaz
Affiliation: Massachusetts General Hospital, RaySearch Laboratories, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Defining radiation target volumes with accurate integration of the neuroanatomy is one of the major difficulties in designing glioma treatments. We developed a deep learning network for norma...
Authors: George Agrotis, Marios Myronakis, Dimitrios Samaras, Kyriaki Theodorou, Ioannis Tsougos, Vassilios Tzortzis, Maria Vakalopoulou, Alexandros Vamvakas, Aikaterini Vassiou, Marianna Vlychou
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Radiology, University of Thessaly, Netherland Cancer Institute, Department of Urology, University of Thessaly, CentraleSupelec, University Paris-Saclay
Abstract Preview: Purpose: Prostate cancer (PCa) diagnosis remains challenging due to discrepancies in Gleason Scoring (GS) and risks of overdiagnosis and underdiagnosis. Multiparametric MRI (mpMRI), including Apparent...
Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...
Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Yufeng Cao, Luigi Marchionni, William Silva Mendes, Cem Onal, Lei Ren, Amit Sawant, Nicole L Simone, Philip Sutera, Phuoc Tran
Affiliation: University of Maryland School of Medicine, 9Department of Radiation Oncology, Thomas Jefferson University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, University of Maryland, Baltimore, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine, Maryland University Baltimore, 8Department of Pathology and Laboratory Medicine, Weill Cornell Medicine
Abstract Preview: Purpose: This study aims to predict 2-yr Metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) patients treated by metastasis-directed therapy (MDT) by devel...
Authors: Daylin Barroso, Chris Beekman, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Robert Joseph Dawson, Walter Murfee, Harald Paganetti, Andrew Robert Sforza, Julia D. Withrow
Affiliation: Massachusetts General Hospital - Harvard Medical School, Massachusetts General Hospital, University of Florida
Abstract Preview: Purpose: To develop methods for quantifying the interaction of radiation with blood in the mouse whole body (MOBY) phantom for dosimetric applications. The most important of these are modeling the dis...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Jiajian Shen
Affiliation: Department of Radiation Oncology, Mayo Clinic, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study aims to develop the first SPArc optimization algorithm based on the Dynamic Programming (SPArc-DP), to improve the treatment delivery efficiency for synchrotron-accelerator-based P...
Authors: Catherine Coolens, Janny Yeyoung Kim, Michael Milosevic, Noha Sinno
Affiliation: Princess Margaret Hospital, University of Toronto
Abstract Preview: Purpose: In solid tumors, Interstitial fluid pressure (IFP) acts as a barrier to molecular transport to the tumor center and serves as a predictor of cancer patientsâ treatment responsiveness. The nov...
Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Gagandeep Saini, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study examined the impact of varying the pitch factor in hippocampal-avoidance whole-brain (HP-WB) radiotherapy treatments, utilizing the newly introduced VOLO Ultra optimization for Hel...
Authors: Xun Jia, Youfang Lai
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Ultrahigh dose rate FLASH (>40 Gy/s) radiotherapy (RT) has attracted significant attention. The mechanism remains unclear, hindering clinical translation. This study investigated the behavior...
Authors: Lili Chen, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: 5-aminolevulinic acid (5-ALA)-mediated radiodynamic therapy (RDT) has been shown to be an effective treatment option using high-energy photon beams. RDT utilizes tumoricidal capabilities caus...
Authors: Peter Jermain, Ying Niu, Abdul Rashid, Yuan Yuan, Mohammad Zarenia
Affiliation: Medstar Georgetown University Hospital, MedStar Georgetown University Hospital, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: ZAP-X is a self-shielded radiosurgery system that utilizes a linac-based isocentric technique and a compact gyroscopic gantry design. While it provides a large solid angle for beam orientatio...
Authors: Jimmy Caudell, Eduardo G. Moros, Nour Nasser, Gage H. Redler, George Yang
Affiliation: Moffitt Cancer Center
Abstract Preview: Purpose: Dosimetric evaluation of PTV margin reduction for Head and Neck(H&N) sequential boost plans using the Ethos online adaptive radiotherapy(oART) system to investigate the tradeoff in decreased ...
Authors: Kenny Guida, Hongyu Jiang, Harold Li, Hem Bahadur Moktan Tamang
Affiliation: University of Nebraska Medical Center, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Varian Eclipse v18.0 introduced Enhanced Leaf Model (ELM) of MLC, which provides better dose calculation accuracy than original DLG-based MLC model. The leaf-gap (LG) parameter for ELM repres...
Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu
Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...
Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong
Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University
Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...
Authors: Andres Portocarrero Bonifaz, Ian Schreiber
Affiliation: CARTI Cancer Center
Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: Hansong Bai, Peter Jermain, Xun Jia, Heng Li, Devin Miles, Daniel Sforza, Michael H. Shang, Daniel Robert Strauss, Keith Unger, Lingshu Yin
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, MedStar Georgetown University Hospital, Johns Hopkins University, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: To investigate DNA Double Strand Break (DSB) induced by FLASH proton irradiation in a repair-free plasmid DNA model under different free radical scavenging conditions in plateau and Bragg pea...
Authors: Yuqi Yang, Fang-Fang Yin
Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...
Authors: Niki Fitousi, Stanley Thomas Fricke, Anna Romanyukha
Affiliation: Qaelum NV, Children's National Hospital
Abstract Preview: Purpose:
To identify opportunities for improvement through investigation of outliers in exam dose length product (DLP) and patients receiving high cumulative doses (CED), in the context of our âped...
Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...
Authors: Molokotima Kekana, Dennis S. Mackin, Stephen W. Peterson, Jerimy C. Polf
Affiliation: Department of Physics, University of Cape Town, M3D, Inc, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: To study the imaging characteristics of a prototype prompt gamma (PG) imaging system consisting of multiple rotating Compton cameras (CC).
Methods: The prototype CC imaging system is c...
Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health
Abstract Preview: Purpose: This study involved the use of Accurayâs TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accurayâs Radixact machine, and dose calculation algorithm, do...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Hajar Moradmand, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, University of Maryland, Baltimore County, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: We are developing a novel Compton Camera (CC) system mounted orthogonally on the treatment nozzle for prompt gamma (PG) imaging-based proton range verification during treatment. This study in...
Authors: Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Minesh P. Mehta, Andrew J. Wroe, Jen Yu
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: Linear energy transfer (LET) is directly related to relative-biological-effectiveness dose in proton therapy. This study aims to investigate how the treatment field hinge angles affect LET of...
Authors: Nicole C. Detorie, Steven M. Kirsner, Remy Y. Manigold
Affiliation: Scripps Cancer Center
Abstract Preview: Purpose:
Dosimetric Leaf Gap (DLG) is an important factor in obtaining the proper beam model in the Eclipse treatment planning system. The purpose of this study was to investigate the dosimetric im...
Authors: Konstantinos Chatzipapas, George C. Kagadis, Panagiotis Konstas, Dimitris N. Mihailidis, Dimitris Visvikis
Affiliation: LaTIM, INSERM UMR1101, University of Pennsylvania, LaTIM, INSERM, University of Brest, University of Patras
Abstract Preview: Purpose: This study investigates the temporal evolution of radiolytic species (H3O+, OHâą, OH-) in water under electron and proton irradiation using the mesoscopic chemistry model that allows longer te...
Authors: Meghan Lubner, Aria M. Salyapongse, Teva Shapiro, Scott D. Slavic, Timothy P. Szczykutowicz, Giuseppe Toia, Zhye Yin
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose:
To compare iodine quantification on a prototype deep silicon photon-counting detector (PCD) CT and conventional clinical energy-integrating (EID) dual-energy (DE) CT.
Methods:
A phan...
Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Ching-Ling Teng, Nadia M. Vassell
Affiliation: Northwell, Mount Sinai Beth Israel
Abstract Preview: Purpose:
The flexible nature of ballistic gelatin and 3D printed material such as PLA lend themselves to phantom studies in brachytherapy. While these materials can allow for easy simulation of cat...
Authors: Amanda J. Deisher, Andrew YK Foong, Witold Matysiak, Jing Qian, Xueyan Tang, Erik J. Tryggestad, Mi Zhou
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Phase gating is commonly employed to mitigate the impact of tumor motion in radiotherapy. Due to the machine-specific time delay between triggering and radiation delivery, the triggering sign...
Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou
Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...
Authors: Hao Gao, Jiayue Han, Wangyao Li, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Proton therapy leverages Bragg-peak-based dose delivery to achieve ultra-high-dose-rate FLASH with patient-specific range modulators (PSRM). Current proton FLASH (pFLASH) planning typically i...
Authors: Stewart J. Becker, Andrew Genuit, Mariana Guerrero, Yannick P. Poirier
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To introduce an additional quality assurance step to prevent human error in vial mix-ups during Yttrium-90 (Y90) radioembolization by verifying the local assay at the time of delivery. We pro...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...
Authors: Xiangli Cui, Zilei Fu, Man Hu, Wanli Huo, Xiaoqing Wu, Jianguang Zhang, Yingying Zhang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
Using Stable Diffusion to generate images of the knee in different disease states can enrich the medical imaging database and inject new vitality into the field of medical imaging analysis...
Authors: Justus Adamson, John Ginn, Yongbok Kim, Ke Lu, Trey Mullikin, Xiwen Shu, Chunhao Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose:
To develop a knowledge-based deep model for synthetic CT (sCT) generation from a single MR volume in frameless radiosurgery (SRS), eliminating the need for CT simulation prior to the SRS d...
Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka
Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...
Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the filmâs energy dependence between kV and MV energies.
Methods: A single 8âx10â LD-V...
Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...
Authors: Hassan Bagher-Ebadian, Anthony J. Doemer, Ryan Hall, Joshua P. Kim, Bing Luo, Benjamin Movsas, Humza Nusrat, Kundan S Thind
Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health
Abstract Preview: Purpose: This study investigates the development and feasibility of local LLM-based agents to automate radiotherapy treatment planning, aiming to improve planning efficiency and consistency, while pre...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
This study aims to leverage large language model (LLMs) to develop a human-in-the-loop agentic framework, enhancing the efficiency of treatment planning in radiotherapy.
Methods:
A L...
Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi
Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital
Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...
Authors: Mark Anastasio, Hua Li, Zhuchen Shao
Affiliation: Washington University School of Medicine, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Automated semantic segmentation of cell nuclei in microscopic images is vital for disease diagnosis and tissue microenvironment analysis. However, obtaining large annotated datasets for train...
Authors: Guha Balakrishnan, Osama R. Mawlawi, Yiran Sun, Ashok Veeraraghavan
Affiliation: RICE University, UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Previous deep learning (DL) techniques such as X2CT-GAN [1] has shown great promise in reconstructing realistic CT volume from biplanar X-rays, however they introduce numerous artifacts in...
Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh
Affiliation: Tufts Medical Center
Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...
Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...
Authors: Christopher P. Favazza, Andrea Ferrero, Taylor Froelich, Forrest Linch, Scott Thompson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Photon counting detector (PCD) CT is a promising tool to enhance pre-procedural planning and intra-procedural guidance for prostate artery embolization due to its unsurpassed ultra-high spati...
Authors: Yan Dai, Jie Deng, Christopher Kabat, Weiguo Lu, Ying Zhang, Hengrui Zhao
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
MRI-guided adaptive radiotherapy (MRgART) using MR-LINAC systems offers significant advantages for liver cancer, enabling superior tumor delineation and online plan adaptation. However, ma...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...
Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...
Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang
Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute
Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...
Authors: Ben Piacitelli, Celeste Winters
Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University
Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...
Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez
Affiliation: University of Houston, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To improve lung dosimetry for 90Y-radioembolization planning, CT-based techniques have been proposed for patient-specific lung mass estimation instead of assuming nominal 1 kg lung masses. He...
Authors: Ryan Gentzler, Xin He, James Larner, J.T. Morgan, Cam Nguyen, Wendy Stewart, Krishni Wijesooriya, Grant Williams
Affiliation: Department of Physics, University of Virginia, Department of Radiation Oncology, University of Virginia, Division of Hematology & Oncology, Department of Medicine, University of Virginia
Abstract Preview: Purpose: Some recent studies have shown Overall Survival (OS) of advanced-stage lung cancer patients treated with chemo-radiation therapy (CRT) is correlated with heart dose [1-5], while in other stud...
Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard
Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...
Authors: Madhava Aryal, James M. Balter, Yue Cao, Daniel T Chang, Kyle Cuneo, Joseph R. Evans, Theodore Lawrence, John Rice, Randall K. Ten Haken, Lise Wei
Affiliation: University of Michigan, Department of Radiation Oncology University of Michigan
Abstract Preview: Purpose: This study aims to identify predictors of global liver function change measured by albumin-bilirubin (ALBI) score following stereotactic body radiation therapy (SBRT) in hepatocellular carcin...
Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying
Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital
Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...
Authors: Waleed Mutlaq Almutairi, Ke Colin Huang, Vishwas Mukundan, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue
Affiliation: Purdue University, Indiana University School of Medicine, Department of Radiation Oncology, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, Purdue University, West Lafayette, Indiana, USA
Abstract Preview: Purpose:
This study aimed to develop a machine learning (ML) model for early prediction of chemoradiotherapy (CRT) response in order to enhance personalized treatment selection for oral or orophary...
Authors: Won Chang, Vadim L. Stakhursky, Yevgeniy Vinogradskiy
Affiliation: Jefferson Einstein, Alliance Cancer Specialists, Thomas Jefferson University
Abstract Preview: Purpose: 4DCBCT is a powerful tool for localization of moving targets when treating lung tumors with hypofractionated regimens (SBRT). However, for patients with implanted cardiac devices (ICD) in clo...
Authors: Jeffrey Andrews, Nathan E. Becker, Juanita Crook, Andrew Jirasek, Matthew Jonathan Muscat
Affiliation: UBC, BC Cancer Agency, BC Cancer
Abstract Preview: Purpose: To map dosimetry and imaging information to ultrasound and multi-parametric magnetic resonance (mpMR) guided trans-perineal core-needle biopsies, performed during two-fraction prostate high-d...
Authors: Alanah M. Bergman, Marc W Deyell, Tania Karan, Jakob Marshall, Justin Poon, Devin Schellenberg, Steven Thomas, Richard Thompson
Affiliation: University of British Columbia, University of Alberta, BC Cancer
Abstract Preview: Purpose: A conservative approach to account for random errors due to intra-fraction cardiac and respiratory motion during cardiac radioablation (CR) is to define a margin equal to the amplitude of car...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patientsâ setups. MAHR complements current image-guidance...
Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University
Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere
Affiliation: University of Chicago
Abstract Preview: Purpose: We assess two multi-measurement acquisition schemes for material decomposition with x-ray phase-contrast imaging (XPCI); demonstrating for the first time that multi-distance imaging can match...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: David P. Adam, Bryan Bednarz, Tyler J Bradshaw, Wesley S. Culberson, Clifford G. Hammer, Sean Jollota, Ohyun Kwon, Jordan Teague
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiology, University of Wisconsin - Madison
Abstract Preview: Purpose: To quantify absorbed dose to water from 90YCl using thermoluminescent dosimeters (TLDs) and to acquire partial volume corrections for 90YCl positron emission tomography (PET).
Methods: Six...
Authors: Wamied T. Abdel-Rahman, Iqbal AlAmri, Lma Alahmare, Ghada Aldosary, Marwa Alghamdi, Lujain Aljadou, Yarah Alkhulaif, Abdullah A. Alshreef, Ohoud Alsubaie, Hoton Alsufyani
Affiliation: Loma Linda University Medical Center, Princess Nourah Bint Abdulrahman University, King Fahad Specialist Hospital, KAMC- Ministry of National Guard Health Affairs, SQCCCRC, KASCH- Ministry of National Guard Health Affairs
Abstract Preview: Purpose: The shortage of qualified medical physicists in many developing countries is due to multiple factors such as lack of awareness or access to graduate and residency training programs. An outrea...
Authors: Abdullah A. Alshreef, Elizabeth L. Bossart, Ashley Cetnar, Leonard H. Kim, Neil A. Kirby, Anna E. Rodrigues, Xin Wang, You Zhang
Affiliation: University of Miami, The University of Texas MD Anderson Cancer Center, Loma Linda University Medical Center, MD Anderson Cancer Center at Cooper, Cooper Medical School of Rowan University, The Ohio State University - James Cancer Hospital, UT Health San Antonio, Duke University, 5940 forest park road
Abstract Preview: Purpose: AAPM TG-298 reported several concerns regarding the training and education of alternative pathway candidates. Medical physics postdoctoral research, though not part of the certification pathw...
Authors: Ziqi Gao, Lei Xing, Siqi Ye, S. Kevin Zhou
Affiliation: Department of Radiation Oncology, Stanford University, University of Science and Technology of China (USTC)
Abstract Preview: Purpose: To address the challenge of high memory usage in volumetric cone-beam CT (CBCT) imaging, we propose a method that combines joint reconstruction and super-resolution for sparsely sampled CBCT ...
Authors: Andrew Alexander, Brecca Bettcher, Bradley T Christian, Jose Guerrero-Gonzalez, Steven Kecskemeti, Lisette LeMerise, Max McLachlan, Andrew McVea, Matthew Zammit
Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center
Abstract Preview: Purpose: Individuals with Down syndrome (DS) develop Alzheimerâs Disease (AD) with very high prevalence (>90%). Neuropathology includes amyloid plaque (AÎČ) accumulation, followed by neurofibrillary ta...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...
Authors: Anthony J. Doemer, Yimei Huang, Benjamin Movsas, Ellen Park, Mira Shah, Salim Siddiqui, Karen C. Snyder, Kundan S Thind, Bo Zhao
Affiliation: Henry Ford Health
Abstract Preview: Purpose: The 6 degrees-of-freedom (6-DoF) robotic couch is considered essential for linac-based stereotactic radiosurgery (SRS), particularly for irregularly shaped targets adjacent to critical organs...
Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...
Authors: Lior Arazi, Gil'ad N. Cohen, Antonio L. Damato, Irene P. Zhang
Affiliation: Unit of Nuclear Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, NYU Grossman School of Medicine, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Diffusing alpha-emitters Radiation Therapy (âAlpha DaRTâ) is a promising new radiation therapy modality for treating bulky tumors. The dose delivered by Alpha-DaRT sources is dependent on the...
Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose: Scatter in X-ray imaging degrades image quality, hindering the visibility of critical anatomical features and complicating patient alignment in radiation therapy. This study aims to improve s...
Authors: Indra J. Das, Ahtesham U. Khan, Andrew J. White, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: During intensity modulated radiotherapy (IMRT) planning, low MU segments (< 3 MU) are commonly avoided due to documented dosimetric nonlinearity and poor reproducibility. This work aims to ex...
Authors: Catherine Coolens, Robert K. Heaton, Lalageh Mirzakhanian, Tasnim Rahman, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, McGill University, Princess Margaret Cancer Centre, Princess Margaret Hospital, University of Toronto
Abstract Preview: Purpose: Commissioning of a Gamma KnifeÂź (GK) (Elekta, Sweden) unit requires precise dosimetric reference measurements, particularly for small fields. The IAEA TRS-483/AAPM TG-155 code of practice (20...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...
Authors: Sam Beddar, Brett Bocian, David B. Flint, Benjamin Abraham Insley, Patrick James Jensen, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Reza Reiazi, Gabriel O. Sawakuchi
Affiliation: University of Miami, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Empyrean Medical Systems, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The Harrison-Anderson-Mick (HAM) applicator is an Ir-192 High-Dose-Rate (HDR) intraoperative radiotherapy device. It features a silicone body with embedded catheters that guide the Ir-192 sou...
Authors: Hongjing Sun, Weibing Yang, Timothy C. Zhu, Yifeng Zhu
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: This study aims to compare the commissioning results of TrueBeam and Halcyon linear accelerators with Monte Carlo (MC) simulations conducted using TOPAS. The ultimate goal is to leverage MC s...
Authors: Mandar S. Bhagwat, Casey Y. Lee
Affiliation: Duke University, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: TG43-based dose calculation leads to inaccurate field-size dependent dose calculation in superficial HDR brachytherapy, due to full-scatter condition accounted in TG43, but not during treatme...
Authors: Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: N/A...
Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb
Affiliation: GenesisCare
Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...
Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati
Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...
Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie
Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine
Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...
Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...
Authors: Smith Apisarnthanarax, Stephen R. Bowen, Sunan Cui, Jie Fu, Clemens Grassberger, Yulun He, Yejin Kim, Matthew J. Nyflot, Sharon Pai
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: 99mTc-sulfur colloid SPECT imaging enables quantitative assessment of voxel-wise liver function in patients with hepatocellular carcinoma (HCC). Accurately predicting post-radiotherapy (RT) l...
Authors: Laurence Edward Court, Alexandra Olivia Leone, Zhongxing Liao, Saurabh Shashikumar Nair, Joshua S. Niedzielski, Ramon Maurilio Salazar, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Radiation Pneumonitis (RP) predictive models often rely on clinical and DVH parameters, but multiomic features from CT imaging and 3D dose distributions from various regions could provide add...
Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas
Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...
Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...
Authors: Corentin Desport, Dominique Iacchetti, Nicolas Kien, Ramiro Moreno, Melodie Munier, Séléna Pondard
Affiliation: Fibermetrix, Alara Expertise, Alara Group
Abstract Preview: Purpose: To evaluate the efficiency of organ-based tube current modulation (OBTCM) in thoracic and abdominopelvic Computed Tomography (CT) for different radiology departments and manufacturers. This s...
Authors: Qianxi Ni, Xian Xiong
Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
Abstract Preview: Purpose:
Poly(ADP)-ribose polymerase inhibitors (PARPi) have brought a significant breakthrough in the maintenance treatment of ovarian cancer. However, beyond BRCA mutation/HRD, the direct impact ...
Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University
Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...
Authors: Kaitlyn M Betz, David Dunkerley, Eric Johnson, Kalina V Jordanova, Kathryn E. Keenan, Samuel D Oberdick, Gregory P. Penoncello, Stephen E Russek
Affiliation: Dept of Radiology, Stanford, University of Colorado School of Medicine, NIST, College of Wooster
Abstract Preview: Purpose: Examine use of low-field MRI and multiparametric analysis for 3D MRI-readable biomimetic gel dosimetry. Low-field MRIs are compact, inexpensive, and portable. They could be located within rad...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Hassan Bagher-Ebadian, Ahmed I Ghanem, Joshua P. Kim, Chengyin Li, Rafi Ibn Sultan, Kundan S Thind, Dongxiao Zhu
Affiliation: Wayne State University, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Accurate segmentation of the Left Anterior Descending (LAD) artery in free-breathing 3D treatment planning CT is crucial for radiotherapy but remains challenging due to its small size, comple...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate four rectal symptoms with the dose to rectum in patients, who received SBRT with Cyberknife for prostate cancer. Also, to fit those dosimetric and outcome data by using a normal ...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate two urinary symptoms with dose to bladder and urethra in patients who received SBRT with Cyberknife. Also, to use a normal tissue complication (NTCP) model to fit the dosimetric ...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study aims at performing a normal tissue complication probability (NTCP) modeling by fitting the doses to the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) stru...
Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson
Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital
Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...
Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang
Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...
Authors: Peng Dong, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Stanford University
Abstract Preview: Purpose: Volumetric Modulated Arc Therapy (VMAT) optimization is a complex, non-convex problem with numerous variables and intricate constraints. Traditional optimization methods often lack efficiency...
Authors: Ahmet S. Ayan, Estelle Batin, Austin M. Faught, Peter E. Klages, Eunsin Lee, Collin Nappi, Mina Okello, Meghana Ramani, Zachary X. Richards, Parisa Sadeghi
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University
Abstract Preview: Purpose: Neutron doses are not modelled in proton treatment planning systems, so measurements were taken with two independent dosimeter types to quantify representative neutron fetal doses in pencil b...
Authors: Md Mainul Abrar, Yujie Chi
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...
Authors: Stephanie Bennett, Ross I. Berbeco, Guillaume Bort, Needa Brown, Lena Carmes, Sandrine Dufort, Michael John Lavelle, Geraldine Le Duc, Francois Lux, Toby Morris, Zeinaf Muradova, Andrea Protti, Olivier Tillement
Affiliation: University de Lyon, NH TherAGuIX, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Department of Radiation Oncology, Dana-Farber/Brigham and Womenâs Cancer Center, Harvard Medical School, NH TherAguix, Universite de Lyon, Brigham and Women's Hospital, Dana-Farber Cancer Institute
Abstract Preview: Purpose: AGuIX is a theranostic Gd-based nanoparticle currently under phase-2 clinical testing where patients receive 2-3 doses at 1-week intervals prior to imaging and irradiation. AGuIX-Bi is a new ...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Deep learning-based automatic medical image segmentation is increasingly employed in clinical practice, significantly reducing manual workload. However, verifying segmentation results rema...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever
Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center
Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...
Authors: Deng-Yuan Chang, Matthew L. Scarpelli
Affiliation: Purdue University
Abstract Preview: Purpose: Tumor-associated macrophages (TAMs) can be assessed by Ferumoxytol-MRI in breast cancer because they are negatively correlated with the prognosis of patient outcome. However, some studies hav...
Authors: Peymon Ghazi
Affiliation: MALCOVA Inc.
Abstract Preview: Purpose: To develop a near scatterâfree breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...
Authors: Palanisamy Karunanithi, Karthikeyan Perumal, Siva Subramanian Vadivel
Affiliation: Dr. Kamakshi Memorial Hospital
Abstract Preview: Purpose:
Recent advancements in high dose-rate (HDR) brachytherapy include the image guidance, new applicators, and dose calculation algorithms. Brachytherapy has steep dose gradient, hence relativ...
Authors: Jason Ellsworth, Mark Mishra, Jason K Molitoris, Lei Ren, Dario B. Rodrigues, Paul Turner, Graeme Woodworth
Affiliation: University of Maryland School of Medicine, Department of Neurosurgery, University of Maryland School of Medicine, University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Pyrexar Medical
Abstract Preview: Purpose: Hyperthermia therapy (HT) involves increasing tumor temperatures to 40-44°C and is a potent radio- and chemosensitizer for treating solid tumors. Current clinical strategies to heat deep-seat...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...
Authors: Ivan M. Buzurovic, Evangelia Kaza
Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Womenâs Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Recent advances allow for depiction of surface brachytherapy flap applicators using MRI, with empty catheters detected by signal intensity reduction. As manual catheter detection is subjectiv...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Vikas Aragam, Edward Castillo, Richard Castillo, Yingxuan Chen, Yevgeniy Vinogradskiy, Lydia J. Wilson
Affiliation: Thomas Jefferson University, Emory University, University of Texas at Austin
Abstract Preview: Purpose: 4DCT-based ventilation imaging (4DCT-ventilation) has been innovatively applied in radiotherapy treatment planning to minimize doses to functional portions of the lung, known as functional av...
Authors: Ali Al Asadi, Amanda Lynn DiCarlo, Anthony J. Doemer, Jessie Y. Huang, Ian Y Lee, Alexandra Moceri, Adam Robin, Lisa Scarpace, Mira Shah, Salim Siddiqui, Kundan S Thind
Affiliation: Henry Ford Innovations, Henry Ford Health
Abstract Preview: Purpose: For a patient who had two previous courses of external beam therapy for rectosigmoid adenocarcinoma and presented with painful, recurrent disease in the sacrum, this study describes the first...
Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.
Abstract Preview: Purpose: The novel machine quality assurance (QA) device nĂŒFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: The Sun Nuclear MapCheck3 device is used for patient-specific QA. While it is typically employed in perpendicular field-by-field delivery using the Isocentric Mounting Fixture, fields not ful...
Authors: Kevin M Brom, Josep Chorro Bas, RosaAnna Chorro Bas, Andres Climent Rubio, Jaydev K. Dave, Tobias Kummer, Larissa Shiue, Donald J Tradup
Affiliation: Mayo Clinic, Prehospital Critical Care Training Group
Abstract Preview: Purpose: To design and evaluate the functionality of a vascular flow phantom for contrast-enhanced ultrasound imaging (CEUS).
Methods: A microcontroller-generated signal was amplified by a cust...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To estimate effective doses associated with different imaging protocols for hip imaging with a cone beam CT (CBCT) scanner specifically designed for weight-bearing acquisitions.
Methods: A...
Authors: Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Gafchromic film is commonly used for quality assurance in SRS/SBRT. However, its application in low-dose measurements, such as monitoring doses on cardiac implantable electronic devicesâwhere...
Authors: Larry A. DeWerd, Ahtesham Ullah Khan
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Total body irradiation (TBI) technique uses high energy photon beams with extended source-to-surface distances (SSDs) to irradiate the entire patient to prepare them for bone marrow or stem c...
Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...
Authors: Ana Maria Barragan Montero, Damien Dasnoy, Sylvain Deffet, Valentine Dormal, Colin Gaban, Melanie Ghislaine, Valentin Hamaide, Guillaume Janssens, John A. Lee, Eliot Peeters, Danah Pross, Luciano Rivetti, Benjamin Roberfroid, Romain Schyns, Kevin Souris, Edmond S. Sterpin, Sophie Wuyckens
Affiliation: Ion Beam Applications SA, Hospital Riviera-Chablais, UCLouvain, Multitel, Université Catholique de Louvain, IBA, Faculty of Mathematics and Physics, University of Ljubljana, Universite Catholique de Louvain
Abstract Preview: Purpose: Treatment planning systems (TPSs) are essential for simulating and optimizing radiotherapy treatments. However, clinical TPSs are expensive software commercialized by private companies and of...
Authors: Vinay K Banka, Mikalai Budzevich, William R. Gibbons, Mark L. McLaughlin, Jacob Moriarty, Eduardo G. Moros, David L. Morse, Christopher J. Tichacek, Thad J. Wadas
Affiliation: Modulation Therapeutics Inc, Moffitt Cancer Center, University of Iowa
Abstract Preview: Purpose: A targeted alpha therapy drug, 225Ac-MTI-201, has been developed targeting the Melanocortin 1 Receptor for metastatic uveal melanoma and is currently in FIH clinical trials. Since alpha emiss...
Authors: Ibtisam Almajnooni, Victor Cobilean, Milos Manic, Harindra Sandun Mavikumbure, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to optimize the 3D U-Net architecture for dose prediction in lung cancer radiation therapy (RT) plans, particularly in scenarios with limited clinical data, as well as to quan...
Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...
Authors: Paolo Pellicioli, Mohammad Rezaee, Ehsan Tajikmansoury, John W. Wong
Affiliation: Institute of Anatomy, University of Bern, Baltzerstrasse, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine
Abstract Preview: Purpose: Half-value layer (HVL) is a critical parameter for commissioning and quality assurance of preclinical x-ray irradiators. However, measuring HVL in cabinet systems presents challenges due to s...
Authors: Kimyli Lemieux, Xingyu Nie
Affiliation: University of Kentucky/UK HealthCare
Abstract Preview: Purpose: To optimize the selection of calibration radioisotope and its activity for dose calibrator (DC) linearity testing, adhering to ALARA (As Low As Reasonably Achievable) principles while conside...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Darren M. C. Poon, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study investigates optimal treatment strategies utilizing MR-linac for extremity lesions, with a specific focus on a 0.6 cm deep lesion in the right palm. The magnetic field-induced dose...
Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...
Authors: Anthony J. Doemer, Ian Gallagher, Yimei Huang, Jeff A. Riess, Kundan S Thind, Bo Zhao
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Stereotactic body radiation therapy (SBRT) is commonly used for early-stage lung cancer. While pre-treatment CT captures some tumor motion, it may not fully represent intra-fraction motion du...
Authors: Simona Cacciatore, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Julien Smeets, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To evaluate time reduction strategies for the Dynamic Collimation System (DCS) using an IBA (Louvain-la-Neuve, Belgium) proton therapy system. Delivery time for a multi-energy-layer patient s...
Authors: William N. Duggar, John C. White
Affiliation: UMMC, University of Mississippi Medical Center
Abstract Preview: Purpose:
To evaluate the impact of patient motion on PTV coverage for 95% and 90% target volumes in VMAT breast treatment plans and to determine the appropriate flash margins required to maintain r...
Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...
Authors: Charles D. Bloch, Stephen R. Bowen, Bing-Hao Chiang, Alex Egan, Eric C. Ford, Sharareh Koufigar, Dominic A. Maes, Juergen Meyer, Sharon Pai, Frank Rafie, Rajesh Regmi, Jatinder Saini, George A. Sandison, Marco Schwarz, Bishwambhar Sengupta, Tony P. Wong
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington
Abstract Preview: Purpose: This study aimed to optimize the strategy and timing of physics consults for proton prostate patients to improve the patient experience and resource utilization in our radiation oncology depa...
Authors: Xiaohu Li, Jianjun Shen, Guozhi Zhang, Sihua Zhong, Jingjie Zhou
Affiliation: United Imaging Healthcare
Abstract Preview: Purpose:
Visualization of carotid artery vessel wall on computed tomography angiography (CTA) imaging is challenging. This study aims to develop a novel post-processing technique, black-blood compu...
Authors: Weiliang Du
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Winston-Lutz (WL) tests are often used to localize the radiation isocenter of a linac. The selection of gantry and collimator angles can affect the accuracy of the resulting isocenter. The ef...
Authors: Akire Trestrail
Affiliation: University of Wisconsin
Abstract Preview: Purpose: To investigate the feasibility of using 125I as a HDR directional brachytherapy source.
Methods: Monte Carlo (MC) simulations were performed using the EGSnrc software toolkit. Dose rate di...
Authors: Panagiotis Iliopoulos, Marios Myronakis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly
Abstract Preview: Purpose: To estimate individualized absorbed dose at Organs at Risk (OARs) from kV Cone Beam CT (CBCT) imaging in the pelvic area, prior radiotherapy, and assess excess risk for secondary malignancies...
Authors: B. Gino Fallone, Gawon Han, Keith D. Wachowicz, Mark G. Wright, Eugene Yip, Jihyun Yun
Affiliation: Medical Physics Division, Department of Oncology, University of Alberta, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta, Medical Physics Division, Department of Oncology, University of Alberta and Department of Medical Physics, Cross Cancer Institute, Dept. of Medical Physics, Cross Cancer Institute and Dept. of Oncology, University of Alberta; MagnetTx Oncology Solutions, www.magnetTX.com
Abstract Preview: Purpose: MRI-radiotherapy hybrid systems can guide the therapeutic beam, dynamically adjusting to a moving tumor in real-time. However, there is a time delay from imaging and beam control, requiring p...
Authors: Sarah Dumont, Trevor Ketcherside, An Liu, William T. Watkins, Qiuyun Xu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose:
The RefleXion X1 SCINTIX algorithm convolves beam fluence with real-time PET distributions for tracking and plan adaptation, but radiotherapy Planning Target Volumes (PTVs) are often signi...
Authors: Wookjin Choi, Michael Dichmann, Adam Dicker, Nilanjan Haldar, Yingcui Jia, Nicole L Simone, Eugene Storozynsky, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University, 9Department of Radiation Oncology, Thomas Jefferson University
Abstract Preview: Purpose: Cardiotoxicity remains a significant limitation for lung cancer patients treated with radiotherapy. Pre-radiotherapy cardiac conditions increase the probability of patients developing cardiot...
Authors: Manju Liu, Ning Wen, Fuhua Yan, Yanzhao Yang, Zhenyu Yang, Haoran Zhang, Lei Zhang, Yajiao Zhang
Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy where precise segmentation of tumors and adjacent vessels is crucial for effective treatment planning. This study dev...
Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Michael Lassmann, Maikol Salas-Ramirez, Bangho Shin, Johannes Tran-Gia, Yitian Wang
Affiliation: Department of Nuclear Medicine, University Hospital WĂŒrzburg, University of Florida
Abstract Preview: Purpose: Conduct a parameterized library of mesh-type skeletal models across the lumbar vertebrae. In radiopharmaceutical dosimetry, the hematopoietic active bone marrow is typically a dose-limiting n...
Authors: Zhihua Qi
Affiliation: Henry Ford Health
Abstract Preview: Purpose: State of the art cardiac CT has built-in automated, patient specific optimization, taking into account a number of factors including patient size, heart rate and others. It is crucial to deve...
Authors: Yao Chen, Lesley A Jarvis, Allison Matous, Rongxiao Zhang
Affiliation: Dartmouth College, University of Missouri, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: Precise patient positioning is critical in accelerated partial breast irradiation (aPBI) to ensure accurate dose delivery to the tumor bed while minimizing exposure to surrounding healthy tis...
Authors: Blessing Akinro, Soumyanil Banerjee, Ming Dong, Carri K. Glide-Hurst, Prashant Nagpal, Chase Ruff, Nicholas R. Summerfield, Timothy P. Szczykutowicz
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Departments of Radiology and Medical Physics, University Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Computer Science, Wayne State University, Department of Human Oncology
Abstract Preview: Purpose: Radiation dose to coronary arteries (CAs) during thoracic radiotherapy (RT) is linked to cardiotoxicity. However, precise CA delineation for avoidance is limited by image quality and CA compl...
Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...
Authors: Wouter Crijns, Frederik Maes, Loes Vandenbroucke, Liesbeth Vandewinckele
Affiliation: Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven; Department of Radiation Oncology, UZ Leuven, Department ESAT/PSI, KU Leuven; Medical Imaging Research Center, UZ Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven
Abstract Preview: Purpose: To explore intentional deep overfit learning (IDOL) to exploit the initial treatment plan to predict an adaptive radiotherapy plan.
Methods: A conditional generative adversarial network is...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Wesley E. Bolch, Emily L. Marshall, Dhanashree Rajderkar, Wyatt Smither
Affiliation: University of Florida
Abstract Preview: Purpose: To determine the accuracy of TotalSegmentator, an AI-based automatic segmentation toolkit, on pediatric CT scans as the original software was trained on adult image datasets with a mean patie...
Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez, Armeen Mahvash, Ali Yousefi
Affiliation: University of Houston, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Patient-demographics-model-based liver volumetry is well-established for determining the future liver remnant following hepatectomy. We used gold-standard CT liver segmentation to validate th...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, John Rong
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose: We aimed to understand the physical performance of a CdTe PCD-based detector system within a whole-body PCD-CT scanner, with the goal of optimizing its clinical application. Instead of relyin...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng Peopleâs Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patientâs inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: NadÚge Anizan, David Broggio, Désirée Deandreis, Didier Franck, Camilo Garcia, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard
Affiliation: Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, Gustave Roussy, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS
Abstract Preview: Purpose: This work aimed at developing an innovative workflow for 177Lu-PSMA personalized dosimetry to lesions and organs at risk (OAR) simultaneously, considering the cross-irradiation from bone meta...
Authors: Ali Ajdari, Thomas R. Bortfeld, Zhongxing Liao, Mara Schubert, Katrin Teichert
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Fraunhofer ITWM
Abstract Preview: Purpose: Radiotherapy (RT) treatment planning often involves solving a multi-criteria optimization (MCO) problem. Conventionally, MCO considers a set of generic (population-wide) dosimetric criteria, ...
Authors: Loren Bell, Charles S Cathcart, Brett William Eckroate, Harold Y Hu, Joshua Kilian-Meneghin, Ke Nie, Fredrick Warburton, Zhenyu Xiong, Keying (Karen) Xu, Ning J. Yue, Yin Zhang, Lili Zhou
Affiliation: RWJBarnabas Health, Basis Scottsdale, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: This study compares the dosimetric impact of multiple metal artifact reduction (MAR) algorithms from different CT simulator vendors using an anthropomorphic head phantom for head-and-neck (H/...
Authors: Mohammed Alzaabi, Abderaouf Behouch, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: Spectral Photon Counting CT (SPCCT) has emerged as a transformative technology in CT imaging capable of producing images from distinct energy windows, allowing improved material characterizat...
Authors: Chao Guo, Xinhua Li, Michael F. McNitt-Gray, Di Zhang, Yifang (Jimmy) Zhou
Affiliation: UCLA, David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The objective was to quantify the liver fat volume fraction (FVF) with virtual monochromatic imaging (VMI) using photon-counting CT (PCCT) and dual energy CT (DECT).
Methods: A custom desi...
Authors: Ricardo Garcia Santiago, Narges Miri, Daryl P. Nazareth, Ankit Pant, Mukund Seshadri
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To develop a transformer-based deep learning network framework for predicting VMAT dose distributions. This can provide fast and efficient calculations with accuracies potentially comparable ...
Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...
Authors: Shifeng Chen, Erica Fisler, Arun Gopal, Mariana Guerrero, Jason Hendershot, Kai Huang, Eric Kusmaul, Adam Schrum, Megan Steinberg, Kai Wang
Affiliation: University of Maryland School of Medicine, Department Radiation Oncology, Kaufman Cancer Center, Upper Chesapeake Medical Center, University of Maryland Medical System Central Maryland Radiation Oncology, Department of Radiation Oncology, University of Maryland Medical Center, Baltimore Washington Medical Center Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
Our goal is to develop and clinically deploy an automated planning tool using multicriteria optimization (MCO) for VMAT in prostate only, whole pelvis radiotherapy treatments.
Methods:<...
Authors: Hyunuk Jung, Fiona Li, Brian Marples, Michael Milano, Sean M. Tanny, Dandan Zheng, Yuwei Zhou
Affiliation: Department of Radiation Oncology, University of Rochester, University of Rochester Medical Center, University of Rochester
Abstract Preview: Purpose:
Recurrent GBM remains one of the most challenging cancers, with limited treatment options. We investigated potential planning parameters of SFRT, a novel radiotherapy technique that delive...
Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din
Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University
Abstract Preview: Purpose: This study introduces a novel approach for patient-specific quality assurance in proton beam therapy, utilizing new plastic scintillator detectors with high temporal resolutions to create det...
Authors: Lars R Furenlid, Chiao Huang, Matthew A. Kupinski, Brian W. Miller
Affiliation: University of Arizona, Departments of Radiation Oncology and Medical Imaging, University of Arizona
Abstract Preview: Purpose: To sample random numbers of decay of radiotracers in a pharmacokinetic compartment model for Monte-Carlo simulation of imaging in targeted alpha therapy.
Methods: Time-activity curves (TAC...
Authors: Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke
Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health
Abstract Preview: Purpose: Precisely identifying orientation of implanted seeds on post-implant CTs is challenging. This research addresses the dosimetric uncertainties stemming from uncertainties in identifying seed o...
Authors: Osama R. Mawlawi, Yiran Sun
Affiliation: RICE University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Conventional PET reconstruction methods often produce noisy images with artifacts due to data/model mismatches and inconsistencies. Recently, deep learning-based conditional denoising diffusi...
Authors: Marcos Feijoo, Mamoru Ichiki, Tatsuya Maeda, Tatsuhiro Makino, Tomonori Megumi, Tadashi Nakabayashi, Yukino Nakata, Shuichi Ozawa, Daishi Takayama
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Blue Physics LLC, Imamura General Hospital, Accuray Inc.
Abstract Preview: Purpose: This study aims to accurately measure the leaf open time (LOT) of the multi-leaf collimator (MLC) in tomotherapy using an advanced plastic scintillator detector (PSD) with high time resolutio...
Authors: Payman Hejazi, Faraz Kalantari, Milad Peer-Firozjaei, Romina Pourhashem, Ehsan Tajikmansoury
Affiliation: Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Medical Physics, Semnan University of Medical Sciences, Department of Medical Physics, Semnan University of Medical Sciences, Semnan, Iran, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine
Abstract Preview: Purpose:
Pretreatment biodistribution imaging play a crucial role in optimizing tumors and organ absorbed doses estimation in radionuclide therapy. Surrogating radionuclides for more efficient trea...
Authors: David Alcorta, Joseph Farina, Timothy Haystead, Yiping He, Philip Hughes, David Loiselle, Marybeth Nedrud, Victoria J. P. Radosova, Jianpeng Yu
Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Duke University School of Medicine, Duke Cancer Institute
Abstract Preview: Purpose: Targeted radiopharmaceuticals have become of widespread interest in the scientific community given their ability to detect and treat metastatic disease. We aim to validate the use of novel ch...
Authors: John Ginn, Zhuoyun Huang, Yongbok Kim, Ke Lu, Chunhao Wang, Yibo Xie, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose: This study aims to develop and validate a machine learning model for predicting V60%, a critical dosimetric metric in LINAC-based Single-Isocenter-Multiple-Targets (SIMT) stereotactic radiosu...
Authors: Qianxi Ni, Qionghui Zhou
Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
Abstract Preview: Purpose:
This study aims to develop and evaluate interpretable machine learning models that use radiomic and dosimetric features to predict HT in advanced cervical cancer patients.
Methods:
R...
Authors: Jeremy T. Booth, Martin Andrew Ebert, Robert Finnegan, Annette Haworth, George Hruby, Burhan Javed, Kazi Ridita Mahtaba, Leyla Moghaddasi, Yutong Zhao
Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, The University of Sydney, The University of Western Australia, Genesis Care, Rockhampton Hospital
Abstract Preview: Purpose:
To evaluate the efficacy of an atlas-based tumor control probability (TCP) model in predicting prostate cancer (PCa) recurrence by retrospectively integrating patient-specific primary radi...
Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROCâs proton phantom program.
Methods: IROCâs proton QA program has six proton...
Authors: David Alcorta, Joseph Farina, Timothy Haystead, Philip Hughes, Keshav Jha, Mark Oldham, Victoria J. P. Radosova
Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: This study attempts to simulate the activation of targeted photodynamic molecules using visible laser light and characterize the direct Reactive Oxygen Species (ROS) generated by Cherenkov an...
Authors: Eric Aliotta, Michalis Aristophanous, Joseph O. Deasy, Bill Diplas, Milan Grkovski, James Han, Vaios Hatzoglou, Jeho Jeong, Nancy Y Lee, Ramesh Paudyal, Nadeem Riaz, Heiko Schoder, Amita Shukla-Dave
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To forecast radiotherapy treatment response for head and neck cancer (HNC) using multimodality imaging and personalized radiobiological modeling.
Methods: Multi-modality imaging data from ...
Authors: Ozan Cem Guler, William Silva Mendes, Sangbo Oh, Cem Onal, Lei Ren, Apurva Singh, Phuoc Tran
Affiliation: University of Maryland School of Medicine, Baskent University Faculty of Medicine, Department of Radiation Oncology, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To predict metastasis-free survival (MFS) for patients with prostate adenocarcinoma treated with androgen deprivation therapy and external radiotherapy using clinical factors and radiomics ex...
Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki
Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...
Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Lizbeth Ayala-Dominguez, Aaron L Carrel, Diego Hernando, Gabrielle L Hoffmann, Amber Possell, Ivan M. Rosado-Mendez, Jiayi Tang, Andrew Wentland
Affiliation: Department of Pediatrics, University of Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Medical Physics, University of Wisconsin-Madison, Departments of Medical Physics and Radiology, University of Wisconsin-Madison
Abstract Preview: Purpose: Metabolic dysfunction-associated steatotic liver disease (MAFLD) is the leading cause of chronic liver disease in children. While biopsy remains the diagnostic standard, non-invasive imaging ...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (â„6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...
Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...
Authors: Muhammad Ramish Ashraf, Clinton Gibson, Gregory Szalkowski, Lei Wang, Siqi Wang, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To develop a neural network-based super-resolution framework for enhancing the resolution of sparse dosimetry measurements in patient-specific radiotherapy QA. Sparse detector arrays, such as...
Authors: Eduardo Florian, Osmar Obdulio Hernandez, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Edgar Aparicio Ruiz, Kevin Vega, Vicky de Falla
Affiliation: Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Liga Nacional Contra el CĂĄncer / INCAN
Abstract Preview: Introduccion:
Lattice Radiation Therapy (LRT) is a form of spatially fractionated radiation therapy (SFRT) designed to improve control of large tumors by delivering ablative doses while minimizing ...
Authors: Jeremy T. Booth, Sonja Dieterich, Jonathan Hindmarsh, Paul J. Keall
Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, UC Davis Medical Center, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Prospective hazard analysis (PHA) is a core medical physics function. PHA was investigated by AAPM Task Group 100 for the purpose of keeping patients safe and assessing the risks of novel tec...
Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang
Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University
Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...
Authors: Mireille Conrad, CĂ©dric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon
Affiliation: Clinique De Genolier
Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...
Authors: Ahmad K. Al-Basheer, Andrew Clarke Grice, Kelly E. Hosier, Mark Logsdon, Evan A. Silverstein, Chris Tunnicliff, Chuan Wu
Affiliation: Sutter Medical Foundation, Sutter Health
Abstract Preview: Purpose: For Prostate SBRT Boost treatments, determine whether a uniform 2mm CTV to PTV margin is sufficient to give 95% dose coverage to the CTV in 90% of patients via a modified Van Herk Margin Form...
Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng
Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...
Authors: Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Commissioning surface applicators is notoriously laborious. In addition, when commissioning Varian surface applicators with vertically positioned source, we found limited data and resources a...
Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske
Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ
Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...
Authors: Hyejoo Kang, Andrew Keeler, Mathias Lehmann, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Varian Imaging Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose: Markerless tumor tracking (MTT) using dual-energy (DE) subtraction imaging is being considered as a non-invasive method to track tumors during lung cancer treatment. Prior to clinical impleme...
Authors: Douglas John Moseley, David M. Routman, Satomi Shiraishi, Donald C Smith, Mark R. Waddle
Affiliation: University of Denver, Mayo Clinic
Abstract Preview: Purpose: About 6% of patients treated for the first time in our department have received radiotherapy previously at an outside institution. We aim to provide an automatic quality assurance of identify...
Authors: Teh Lin, Anna Oneil
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...
Authors: Ali Ammar, Quan Chen, Jingwei Duan, Yi Rong, Nathan Y. Yu, Libing Zhu
Affiliation: Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Clinical performance of deep learning-based auto-segmentation (DLAS) can degrade over time due to AI âagingâ from unseen data input compared to the initial model training data. This study aim...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose: Gradient-based optimization is the standard approach for IMRT fluence map optimization (FMO). Recently, a machine learning (ML)-assisted framework using a one-layer neural network was propose...
Authors: Zakaria Aboulbanine, Greeshma A. Agasthya, Paul Inman, Anuj J. Kapadia, Anthony Hong Cheol Lim, Jayasai Ram Rajagopal
Affiliation: Oak Ridge National Laboratory, Georgia Institute of Technology
Abstract Preview: Purpose: The fundamental concept of radiopharmaceutical therapy involves binding radioisotopes to molecules with a known biokinetic distribution, which ensures that the targeted organs receive higher ...
Authors: Haiqa Arain, Ping Xia, Zhexuan Zhang
Affiliation: Cleveland Clinic
Abstract Preview: Purpose: To quantify water contents and thickness of wet towel (as a flexible bolus) on curved surface dose for partial breast irradiation.
Methods: Two VMAT partial breast plans (3000 cGy in 5...
Authors: Eric C. Ford, Awusi Kavuma, Solomon Kibudde, Lilie Lin, Apollo Muramuzi, Nibedita Paul, Peniel T Twum, Afua A. Yorke
Affiliation: Uganda Cancer Institute, MD Anderson Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Nebraska, Global Communities
Abstract Preview: Purpose: Sub-Saharan Africa accounts for over one-third of global cervical cancer deaths, despite representing only 14% of the worldâs female population. At the only RT center in Uganda, prior studies...
Authors: Chih-Chiang Chang, Chingyun Cheng, Ben Durkee, Minglei Kang, Elissa Khoudary, Yangguang Ma, Xuanqin Mou, YuFei Wang, Tengda Zhang, Wang Zhengda
Affiliation: Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xiâan Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xiâan Jiaotong University, Department of Medical Physics, Columbia University, University of Pennsylvania, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study presents a voxel-based analysis method based on deformable image registration to accurately quantify respiratory-induced motion and deformation of both targets and organs at risk (...
Authors: Em Harkness, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
A recently introduced mathematical method quantifies performance-based clinical risk to create a risk-to-risk assessment with radiation risk, rendering the so-called total risk. However, t...
Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer
Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: To evaluate iodine quantification and CT number accuracy in coronary CT angiography (CTA) using standard and ultra-high resolution (UHR) modes of photon-counting CT (PCCT) across different do...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose:
This study investigates the dosimetric impact of systematic and random gantry position errors (GPE) during dynamic Spot-Scanning Proton Arc Therapy (SPArc) delivery.
Methods:
Four ca...
Authors: Rick Holly, Sumudu Katugampola
Affiliation: Gesinger Medical Center, Geisinger Medical Center
Abstract Preview: Purpose:
To quantitatively analyze long term variations in optical density of un-irradiated and irradiated EBT3 radio-chromic films and their effects on dose calibration curves in a clinical settin...
Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz
Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison
Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...
Authors: Casey C. Heirman, Kyle J. Lafata, Xiang Li, Breylon Riley, Jack B Stevens, Tammara Watts
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: To leverage quantitative fluorescence imaging and spatial transcriptomics for characterizing the spatial and molecular heterogeneity of the tumor microenvironment (TME) in HPV+ head and neck ...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Luis E. Fong de los Santos, Douglas John Moseley, Satomi Shiraishi, Cenji Yu
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To quantitatively detect errors in vertebral body localization using normalized cross correlation (NCC)
Methods: Volumetric images of a thoracic end-to-end SBRT phantom with a removabl...
Authors: Julien Bancheri, Chau Giang Bui, David G Cooke, Christopher M Lund, Morgan J Maher, Jan P. Seuntjens, Jason Z Yuan
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Medical Biophysics, University of Toronto, University of Toronto, Medical Physics Unit, McGill University, Department of Physics, McGill University
Abstract Preview: Purpose: The dielectric wall accelerator (DWA) offers a low-cost solution for proton therapy, using non-resonant waveguides to accelerate particles. Radial waveguides (RWGs), consisting of a dielectri...
Authors: Mohammad Nazmul Alim, Regina DeWitt
Affiliation: Department of Physics, East Carolina University,, Department of Physics, East Carolina University
Abstract Preview: Purpose: This study quantifies the ability of Luxel (AlâOâ:C) to measure radiation dose from a Moxtek X-ray source. Key aspects of OSL dosimetry, including OSL curves, dose response, depth dose, and b...
Authors: Alexandru Badalan, Peter Petric, I. Antoniu Popescu, Andrew Kyle Henderson Robertson
Affiliation: Bc Cancer, BC Cancer - Vancouver, BC Cancer
Abstract Preview: Purpose: Ultra-high dose rate (>40 Gy/s) or âFLASHâ radiation therapy (RT) has the potential to improve cancer treatment through reduced radiation side effects. While electron FLASH beams can be produ...
Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose:
To calculate radiobiological metrics of daily dose delivered for head and neck (HN) patients using the daily cone beam CT (CBCT) to generate a pseudo CT (pCT). Moreover, this work compares...
Authors: Ramesh Boggula, Yash Somnay, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC, Wayne State University
Abstract Preview: Purpose: Spatially fractionated radiation therapy (SFRT) allows delivery of therapeutic doses to bulky tumors otherwise limited by dose-volume effects that threaten organ-at-risk tolerances. For negle...
Authors: Lili Chen, Andy T. Clark, Dusica Cvetkovic, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Radiodynamic therapy (RDT) shows promise as a strategy to inhibit the metastasis of premetastatic small cell lung cancer (SCLC). This study evaluates the therapeutic effect of RDT in inhibiti...
Authors: David L. Barbee, David Byun, Ting Chen, Paulina E. Galavis, Siming Lu, Sarah Rosemary Morris, Hesheng Wang, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose: MR-Linac enables dose escalation in prostate SBRT on accurately defined dominant intra-prostate lesion (DIL) on daily MR images. This study aims to evaluate inter-fraction changes in the radi...
Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Allison Pittman, Ashlyn G. Rickard, Breylon Riley
Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To evaluate the relationships between quantitative imaging biomarkers and chemoradiation resistance in head and neck squamous cell carcinoma (HNSCC) using preclinical mouse models.
Met...
Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...
Authors: Nrusingh C. Biswal, Manas R. Gartia, Maria Iftesum, Sanjit K. Roy, Gyana Ranjan Sahoo, Elnaz Sheikh, Hem D. Shukla, Madhur Srivastava
Affiliation: Department of Chemistry and Chemical Biology, Cornell University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Mechanical and Industrial Engineering, Louisiana State University
Abstract Preview: Purpose: Prostate cancer incidence and mortality levels in African-American men are the highest among all ethnic groups. This points to the role of biological factors in driving disparate outcomes. He...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger
Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...
Authors: Keiichi Jingu, Noriyuki Kadoya, Takafumi Komiyama, Takeru Nakajima, Hikaru Nemoto, Hiroshi Onishi, Masahide Saito, Ryota Tozuka
Affiliation: Department of Radiology, University of Yamanashi, Department of Radiation Oncology, Tohoku University Graduate School of Medicine, Department of Advanced Biomedical Imaging, University of Yamanashi
Abstract Preview: Purpose: We evaluated the accuracy of a new AI-based fully automated planning software in stereotactic body radiotherapy (SBRT) for early-stage lung cancer.
Methods: We collected data from 125 pati...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...
Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao
Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.
Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...
Authors: Yi Fan, Andrew Friberg, Costas Koumenis, Kevin Teo, Ioannis I Verginadis, Ledi Wang, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: Glioblastomas (GBM) are aggressive and lethal malignancies characterized by their highly refractory nature, contributing to a five-year survival rate of approximately 7%. Physically, GBM exhi...
Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas
Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco, University of San Francisco
Abstract Preview: Purpose: As Large Language Models (LLMs) continue to evolve, their ability to analyze Electronic Health Record (EHR) notes for clinical decision support expands. Chain of Thought (COT) reasoning, an e...
Authors: David P. Adam, Xun Jia, Youfang Lai, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Radiopharmaceutical therapy is experiencing a resurgence in interest due to its potential of treating widespread metastatic disease in a patient-specific manner. Accurately measuring and desc...
Authors: Francis A Asamoah, David D. Campos, Jordan A Holmes, Ke Colin Huang, Omar Ishaq, Sook Kien Ng, Arpan Prabhu, Edwin Quashie, Yong Yue
Affiliation: Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Evaluate a novel rectal spacer workflow with spacer injection during brachytherapy to streamline logistics, reduce hospital visits and costs, and compare the benefits of SpaceOAR Vue and Barr...
Authors: Matthew Case, Richard Castillo, Sunil Dutta, Edgar Gelover, Katja M. Langen, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory University
Abstract Preview: Purpose: To evaluate the application of LETd and track-end (TE) objective functions during the optimization of breast proton therapy plans to decrease the risk of lung toxicity and rib fractures.
M...
Authors: Andrew Lukban, Kiran Pant, Charlotte Elizabeth Read, Ren-Dih Sheu
Affiliation: Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology
Abstract Preview: Purpose: Ophthalmic brachytherapy relies on Collaborative Ocular Melanoma Study (COMS) protocol and its updated reports. Their reports provide standardized methods for eye plaque brachytherapy, descri...
Authors: Daniel A. Alexander, Jonathan Baron, Brook Kennedy Byrd, William Ross Green, Bolin Li, Rafe A. McBeth, Abigail Pepin, Steven Philbrook
Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, Thayer School of Engineering, University of Pennsylvania
Abstract Preview: Purpose: As accelerated partial breast irradiation (APBI) gains traction, the prospect of a rapid sim-to-completion of treatment workflow is an attractive option for patients. While OAR autocontouring...
Authors: Vishruta A. Dumane, Andrew Lukban, Kiran Pant, Charlotte Elizabeth Read, Ren-Dih Sheu, Nadia M. Vassell
Affiliation: Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology
Abstract Preview: Purpose: This work introduces a refined in-house modified COMS eye plaque management system to streamline processes, reduce redundancies, and enhance usability.
Methods: A web-based application wit...
Authors: William T. Hrinivich, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Volumetric modulated arc therapy (VMAT) planning is a computationally expensive process. In this work, we propose a reinforcement learning (RL) framework to automatically optimize dose rate a...
Authors: Piotr Pater, Nicholas G. Zacharopoulos
Affiliation: McGill University, Medical Physics Unit, Gerald Bronfman Department of Oncology, McGill University
Abstract Preview: Purpose: To develop a method for accurate relative film dosimetry that incorporates non-uniformity
corrections.
Methods: The accuracy of Devicâs [1] linearization approach was evaluated using si...
Authors: Alexander Baikalov, Luke Connell, Nolan M. Esplen, Michele M. Kim, Stephen F. Kry, Emil Schueler, Hayden Scott, Ryan Sun, Paige A. Taylor, Uwe Titt
Affiliation: The University of Texas MD Anderson Cancer Center, University of Pennsylvania, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: to develop an affordable, portable device for accurately measuring FLASH dose rates from protons, electrons, and photons. 4 detectors were utilized to measure the temporal structure of proton...
Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center
Abstract Preview: Purpose: Quantitative T1Ï imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...
Authors: Lili Chen, Xiaoming Chen, Chang Ming Charlie Ma, Joshua Meyer
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Fast CBCT (HyperSight) acquisition technique together with a surface-guided breath-hold (SGBH) would allow a better image quality for accurate target/organ delineation. It facilitates breath-...
Authors: Shixiong Huang, Daming Li
Affiliation: The Affiliated Nanhua Hospital, University of South China, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital
Abstract Preview: Purpose: To assess the feasibility of using target current pulse signals to evaluate the output dose of medical standing wave electronic linear accelerators.
Methods: The Target I signal of the acc...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose: To analyze the actual doses received during radiotherapy for head and neck cancers (HNC) using Velocity, providing insights for adaptive radiotherapy decision-making.
Methods: Thirty-three...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Frameless gamma knife (GK) treatments use a thermoplastic mask coupled with high-definition motion management system that utilizes an infrared camera, and a reflective marker placed on the pa...
Authors: Danielle Renee Daiger, Nicholas N. Sperling
Affiliation: University of Toledo, University of Toledo Medical Center
Abstract Preview: Purpose:
To retrospectively evaluate the impact of planned delivery time on plan quality metrics for breath-hold VMAT SBRT thoracic cancer patients.
Methods:
Patients treated for SBRT thoraci...
Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang
Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill
Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...
Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Bingqi Guo, Andrew Robert Hadfield, Hakan Nordstrom, Jacob Scott, John Suh, Nara Yoon
Affiliation: Adelphi University, Elekta, Cleveland Clinic
Abstract Preview: Purpose: To investigate the biological effect of Spatially Fractionated Radiation Therapy (SFRT) within Gamma-Knife (GK) using retrospective planning for brain metastases patients. This study presents...
Authors: Tirthraj Adhikari, Timothy J Allen, Abdullah A. Alshreef, Clara Ferreira
Affiliation: Medical School Department of Radiation Oncology University of Minnesota, University of Minnesota, Loma Linda University Medical Center
Abstract Preview: Purpose: GammaTile Brachytherapy with 131Cs is an effective treatment for glioblastomas, offering local control with minimal radiation necrosis. While the line source model is preferred for dose distr...
Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cell microstructure information is critical for radiotherapy response assessment. Diffusion MRI (dMRI) offers great potential in deriving cell parameters. Yet parameters estimated in existing...
Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: The CQ Medical kVue Pronumbra Head & Neck (HN) System is a new immobilization device for proton therapy. The mask includes 4 large knobs that attach to the board with built-in shims. These kn...
Authors: Garrett Russell Hamilton, Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Recurrent brain metastasis is very common, and patients who previously received whole-brain radiotherapy (WBRT) may receive an additional course(s) of stereotactic radiosurgery (SRS) to selec...
Authors: Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Edward L. Clouser, Yi Rong, Jun Tan, Jennifer Yan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
To identify planning techniques that consistently result in robust VMAT-TBI plans that allow for larger patient setup errors.
Methods:
Conventional planning method often results in p...
Authors: Yukio Fujita, Satoshi Ishikura, Fumiki Ito, Yujiro Nakajima, Takumi Sakamoto, Naoki Tohyama, Ryohei Yamauchi
Affiliation: Komazawa University Graduate School, St. Luke's International Hospital
Abstract Preview: Purpose: The aperture shape controller (ASC) is an Eclipse feature that increases muti-leaf collimator (MLC) aperture size. This study aimed to evaluate the effects of ASC settings on the robustness o...
Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz
Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison
Abstract Preview: Purpose: This study presents a scientifically quantified case study that underscores the importance of the medical physicistâs contribution to contrast enhancement optimization.
Methods: CT pulmona...
Authors: Jae Won Jung, Daniel Lee
Affiliation: Thomas S. Wootton High School, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: Monkeys have played a key role in enhancing our understanding of the behavior of radioactive materials within living organisms in the field of nuclear medicine. However, detailed dosimetric d...
Authors: Tommaso Frigerio, Joshua Genender, John M. Hoffman, Catherine (Caffi) Meyer
Affiliation: UCLA, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurate bone marrow segmentation is required for bone marrow dosimetry to monitor for dangers in PSMA-Lu177 radioligand therapy. We introduce a hybrid (AI/semantic knowledge) segmentation pi...
Authors: Carl D. Elliston, Lawrence Koutcher, Michael J. Price, Adam C. Riegel, Michael B Sisti, Tony J.C. Wang, Andy (Yuanguang) Xu
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: An inverse treatment planning software was recently introduced to Gamma Knife radiosurgery. The purpose of this study is to compare the plan quality of the Gamma Knife âLightningâ with that o...
Authors: Reza Farjam, Russell K Hales, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam angles and off-axis isocenter selection are important to achieve high quality plan and collision-free delivery in stereotactic body radiotherapy (SBRT) of the posteriorly located...
Authors: Elizabeth K. Butker, Cara Cimmino, Jenna L. Fair, David Matthew Giles, Bruce Hershatter, Shadab Momin, Sagar Patel, John Pattaras, Kamran Salari Salari, Aaron Weiss
Affiliation: Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: Prostate cancer patients may experience a local-only failure after radiation. While high-dose-rate (HDR) brachytherapy may have more favorable toxicity profile and cancer control compared to ...
Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang
Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...
Authors: Angela Gearhardt, Stephen F. Kry, Christopher Ryan Peeler, Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: A growing number of radiation therapy (RT) patients have cardiovascular implantable electronic devices (CIEDs). Patients with CIEDs must be carefully managed because the devices are susceptib...
Authors: Leon Dunn
Affiliation: IsoAnalytics Pty. Ltd.
Abstract Preview: Purpose: The purpose of this work is to present the development and results of an automated Varian Trajectory Log file processing software platform called Sentinel (IsoAnalytics Pty. Ltd.).
Methods...
Authors: Yong Chen, Gilberto Gonzalez, Omprakash Gottam, Liangzhong Xiang
Affiliation: University of California, Irvine, Koneru Lakshmaiah Education Foundation, University of Texas at San Antonio., University of Oklahoma Health Science Center
Abstract Preview: Purpose: Clinics currently lack techniques for real-time, in vivo monitoring of radiation therapy (RT), which is desirable for precise treatment. Radiation-induced acoustic computed tomography (RACT) ...
Authors: Alex Lindgren-Ruby, Jeffrey M. Moirano, Joseph Everett Wishart
Affiliation: University of Washington
Abstract Preview: Purpose:
To evaluate polynomial fitting of signal intensity for signal-to-noise ratio (SNR) estimation from weekly QC ACR MRI phantom images and compare against other SNR estimation methods as well...
Authors: Yijian Cao, Sean T Grace, Marissa Joyce Vaccarelli
Affiliation: Northwell
Abstract Preview: Purpose:
This study investigates the dosimetric efficacy of significantly limiting gantry angles in prostate radiation therapy to as a promising strategy to maintain plan quality while enhancing ma...
Authors: Sameera Kumar, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Difficulty assessing lung limits during treatment planning in the retreatment environment can be compounded as limits are volume-based (ie. VxGy<37%) and require a critical volume with a m...
Authors: Li-Sheng Geng, David Huang, Haoze Li, Xi Liu, Meng Wang, Tianyu Xiong, Ruijie Yang, Weifang Zhang, Meixin Zhao
Affiliation: School of Physics, Beihang University, Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, Peking University Third Hospital, Department of Nuclear Medicine, Peking University Third Hospital, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study aimed to develop a deep learning-based framework for simultaneously generating lung perfusion and ventilation images from three-dimensional computed tomography (3D CT) images.
M...
Authors: Anahita Bakhtiari Moghaddam, Don F. DeJongh, Ethan DeJongh, Jennifer Hardt, Oliver JĂ€kel, Lukas Martin, Alexander Pryanichnikov, Joao Seco, Christina Stengl, Niklas Wahl
Affiliation: Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Division of Biomedical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), ProtonVDA LLC, Department of Physics and Astronomy, Heidelberg University, Division of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT)
Abstract Preview: Purpose:
To evaluate the feasibility and performance of single-plane position tracking for proton and helium pencil beam radiography using a prototype imaging system, with the goal of providing a c...
Authors: Rituparna Basak, Maede Boroji, Renee F Cattell, Vahid Danesh, Imin Kao, Kartik Mani, Xin Qian, Samuel Ryu, Tiezhi Zhang
Affiliation: Stony Brook Medicine, Stony Brook University, Washington University in St. Louis, Stony Brook University Hospital
Abstract Preview: Purpose: Fundamental qualitative characteristics physicians use to differentiate skin lesion subtypes include asymmetry, border irregularity, and color. Radiomic features have potential to quantify th...
Authors: Muhammad Ramish Ashraf, Dixin Chen, Aaron Garza, Lloyd Emmanuel Kamole Ghomsi, Edward Elliot Graves, Billy W Loo, Stavros Melemenidis, Joseph B. Schulz, Lawrie Skinner, Murat Surucu
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: FLASH radiotherapy, supported by robust preclinical evidence showing an improved therapeutic index, is advancing toward clinical trials. Clinical FLASH treatments will likely require scanning...
Authors: Avneesh Chhabra, Zhiyue J. Wang, Qing Yuan
Affiliation: University of Texas Southwestern Medical Center
Abstract Preview: Purpose: Magnetic susceptibility artifacts from dental arches and hardware often compromise MRI neurography of jaw and facial nerves. This study aims to characterize these artifacts and provide insigh...
Authors: Cristel Baiu, Zheng Feng Lu, Dufan Wu, Baihui Yu
Affiliation: University of Wisconsin, Massachusetts General Hospital, University of Chicago
Abstract Preview: Purpose: IEC TS 62791:2022 specified a clinically meaningful and quantitative framework for evaluating diagnostic ultrasound performance by measuring the lesion signal-to-noise ratio (LSNR) using rand...
Authors: Rajeev K. Badkul, Ronald C Chen, Ying Hou, Harold Li, Chaoqiong Ma, Jufri Setianegara
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose:
Postimplant urinary toxicity is common in prostate low-dose-rate (LDR) brachytherapy. We developed a machine learning (ML) model to explore the correlation between spatial dose distributio...
Authors: Hadley Anna DeBrosse, Kevin J. Little
Affiliation: The Ohio State University
Abstract Preview: Purpose: This work examines the consistency and pattern of spatial resolution degradation in weekly quality control (QC) testing prior to CT tube failure and replacement and investigates potential cor...
Authors: Ming Dong, Carri K. Glide-Hurst, Joshua Pan, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Radiation dose to the cardiac nodes is more strongly associated with conduction disorders and arrythmias than whole heart (WH) metrics. However, node segmentation is challenging due to comple...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Filament deposition modeling (FDM) 3D printers may utilize proprietary calibration methods inadequate for medical imaging. Proper techniques are necessary to achieve imaging uniformity standa...
Authors: Wesley S. Culberson, Ryan Gardner, John Thomas Stasko
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin
Abstract Preview: Purpose: X-ray tube voltage is a critical parameter in influencing an X-ray tubeâs beam quality. The endpoint tube potential, the potential difference between the X-ray tubeâs cathode and anode, is pa...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Amanda J. Deisher, Susannah V. Hickling, Shima Ito, Jon J. Kruse
Affiliation: CancerCare Manitoba, Mayo Clinic
Abstract Preview: Purpose:
To date, 11 ocular patients were treated with spot scanning gantry-based gaze-gated ocular proton program at Mayo Clinic, Rochester MN since 2023. Treatments are done in the half-arc gantr...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Karam Ayoub, Aaron B Hesselson, Ronald C McGarry, Joshua Misa, Damodar Pokhrel
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Cardiology
Abstract Preview: Purpose: Noninvasive stereotactic body radiosurgery (SBRS) is emerging treatment option for advanced heart failure patients with refractory-ventricular tachycardia (rVT) who experienced recurrent impl...
Authors: Lori Buchholtz, Alison Garda, Chris L. Hallemeier, Kathryn L. Kolsky, Han Liu, Joseph John Lucido, Marisa Schinter, Andrew J. Veres, Sara Walerak
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The C_START initiative aims to streamline and simplify the Direct-to-Unit (DtU) clinical setup and treatment planning process for photon radiation therapy, particularly for emergent cases suc...
Authors: Eric C. Ford, Yulun He, Minsun Kim, Dustin Melancon, Juergen Meyer, Dong Joo Rhee, Yinghua Tao
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, MD Anderson Cancer Center, University of Washington
Abstract Preview: Purpose: To develop and evaluate an automated-planning technique capable of generating high-quality treatment plans for hippocampal-sparing-whole-brain radiation therapy.
Methods: An auto-planning ...
Authors: Laura I. Cervino, Sharif Elguindi, Yu-Chi Hu, Licheng Kuo, Xiaoning Liu, Jennifer Ma, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Radiation Oncology, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Quad-shot radiotherapy (QSRT) is an emerging paradigm in palliative cancer treatment. This study aimed to streamline the QSRT workflow using automation to improve efficiency while maintain...
Authors: Caroline Cheney, Patricia G Collins, Allen R. Goode, Preston Le, Andrew M. Polemi, Angela Snyder
Affiliation: UVA Health, Atirix Medical Systems
Abstract Preview: Purpose: Optimize ongoing quality control (QC) for radiographic (DR) and fluoroscopic (FL) systems by identifying metrics most sensitive to hardware disruptions among regional noise, pooled noise, sig...
Authors: Samuel Kadoury, Redha Touati
Affiliation: Polytechnique Montréal
Abstract Preview: Purpose:
Generating synthetic CT images from MR acquisitions for radiotherapy planning allows to integrate soft tissue contrast alongside density information stemming from CT, thus improving tumor ...
Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei
Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...
Authors: Serhii Brovchuk, Viktor M. Iakovenko, Nataliya Kovalchuk, Yuliia Lozko, Zoia Shepil, Natalka Suchowerska, Ruslan Zelinskyi
Affiliation: Kyiv Regional Oncology Dispensary, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, School of Physics, The University of Sydney, Medical Physics Department, Medical center of Yuriy Spizhenko, Department of Radiation Oncology, UT Southwestern Medical Center, Stanford Cancer Center
Abstract Preview: Purpose: The full-scale russian invasion of Ukraine has caused the largest humanitarian disaster in Europe since World War II. This study identifies gaps in RT services caused by the war and outlines ...
Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman
Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University
Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul
Affiliation: The University Of Chicago, The University of Chicago
Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...
Authors: Gong Vincent Hao, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami, Ikuno Nishibuchi, Peiying Colleen Ruan, Daguang Xu, Dong Yang
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, NVIDIA
Abstract Preview: Purpose:
Accurate tumor segmentation in head and neck cancer is critical for effective treatment planning, but variability in practices across medical facilities poses challenges for standardizatio...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....
Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...
Authors: Hoyeon Lee
Affiliation: University of Hong Kong
Abstract Preview: Purpose: Deep-learning approaches are widely investigated for Cone-Beam CT (CBCT) scatter correction to improve the quality of the linear-accelerator mounted CBCT. This study aims to optimize the deep...
Authors: Chonthicha Bunchuailuea, David Geeler, Martin Sabel, Claas Wessels
Affiliation: Varian Medical Systems
Abstract Preview: Purpose: Elongated treatment sites, such as craniospinal treatments, pose multiple challenges in todayâs practices, requiring multiple CBCTs for position verifications per fraction, which might increa...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...
Authors: Ă sa K. Carlsson Tedgren, Taran Hellebust, Antonio Herreros, Jacob Johansen, Christian Kirisits, Panagiotis Papagiannis, Mark J. Rivard, Frank-Andre Siebert, Frank Verhaegen, Javier Vijande, Jan Wiersma, Marisol de Brabandere, Ruud van Leeuwen
Affiliation: UKSH, Campus Kiel, Klinik fĂŒr Strahlentherapie (Radioonkologie), Department of Oncology, The Norwegian Radium Hospital, Oslo University Hospital, Radiation Physics, Department of Medicine and Health (IMH), Linköping University, Radiation Oncology Department, Hospital ClĂnic-Universitat de Barcelona, IDIBAPS, IFIC-UV, Radiation Oncology, Amsterdam UMC location University of Amsterdam, Department of Radiation Oncology, Radboud University Medical Center, Department of Oncology, Aarhus University Hospital, University Hospital Gasthuisberg, Dept. of Radiation Oncology, Medical Physics Laboratory, Medical School, National and Kapodistrian University of Athens, Department of Radiation Oncology (MAASTRO), GROW â School for Oncology and Reproduction, Maastricht University Medical Centre+, Department of Radiation Oncology, Comprehensive Cancer Center, Medical University of Vienna, Warren Alpert Medical School of Brown University
Abstract Preview: Purpose: This study, which was carried out by the GEC-ESTRO BRAPHYQS working group, reports the increasing divergence between clinical reference air kerma rate (RAKR) measurements and vendor-provided ...
Authors: Lawrence T. Dauer, Yusuf Emre Erdi, Yiming Gao, Dustin W. Lynch, Usman Mahmood
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Radiation dose to patients in CT examinations (CTDIvol, DLP) is tracked in dose monitoring solutions. Some solutions push for automatically estimating patient organ doses based on exam images...
Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center
Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.
Methods: Clonogenic cell survival w...
Authors: Young-Bin Cho, Jacob Scott, Nara Yoon
Affiliation: Adelphi University, Cleveland Clinic
Abstract Preview: Purpose: The immune system plays a critical role in determining cancer prognosis. Based on our prior study (Cho et al., 2023) about the bystander effect induced by immune responses in spatially design...
Authors: Wen C. Hsi, Tae Kyu Lee, Biniam Yo Tesfamicael
Affiliation: Allina Health, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Oklahoma Proton Center
Abstract Preview: Purpose: When minimal dose-variations induced by inter-fractional anatomical-changes and positioning-deviation were found for having limited impact on clinic-outcomes of oropharyngeal head-and-neck (H...
Authors: David Byun, Ting Chen, Paulina E. Galavis, Allison McCarthy, Hesheng Wang, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To summarize a MR guided adaptive workflow developed for pelvic lymph nodes (PLN) stereotactic radiotherapy using large field size on Elekta Unity© MR Linac system, and to quantitatively anal...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Jenghwa Chang, Chingyun Cheng, J Isabelle Choi, Muhammad Hamza, Minglei Kang, Tyler Kaulfers, Grant Lattery, Haibo Lin, Charles B. Simone, Xingyi Zhao
Affiliation: Peking University, Hofstra University Medical Physics Program, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Physics and Astronomy, Hofstra University, Physics Resident at Montefiore Einstein, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: In terms of high dose rate FLASH, the question remains on how to properly deliver treatment and what clinical sites are feasible to deliver such treatment. The novel Bragg peak (BP-FLASH) and...
Authors: Cem Altunbas, Adam Avant, Farhang Bayat, Roy Bliley, Ian Boor, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi
Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic
Abstract Preview: Purpose: Improved soft tissue visualization plays an important role in target localization and treatment plan adaptation in CBCT-guided radiotherapy. In this work, a novel CBCT approach, 2D antiscatte...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Emily Hansen, Tyler Kaulfers, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Montefiore Einstein University Hospital, Hackensack University Medical Center
Abstract Preview: Purpose: A topic often discussed is the disparity of women in medical physics, overlooking the absence of Black and Hispanic women in the field. The intersectionality within marginalized communities i...
Authors: Xiu tong Lin
Affiliation: Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the dosimetric differences between the photon and proton plans and between the different target according to the placement of the implants for patients undergoing radiotherapy afte...
Authors: Jiayun Chen, Shengqi Chen, Junchao Li, Fei Liu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Tongji Medical College, Huazhong University of Science & Technology, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To assess if 3D Vane MRI can accurately depict the motion of the target volume and OARs.
Methods: This retrospective study included 54 liver cancer patients who underwent both 3D Vane MRI ...
Authors: George X. Ding, Kenneth L. Homann
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: It is standard practice that the beam monitor units (MUs) calculated by a commercial treatment planning system (TPS) is verified by a secondary dose calculation (SDC) software that independen...
Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Thongchai Masilela, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin
Affiliation: University of California San Francisco, Massachusetts General Hospital and Harvard Medical School, Massachusetts General Hospital
Abstract Preview: Purpose: To present the results of 15 years of developments of the TOPAS TOol for PArticle Simulation framework, and to highlight recent and new developments.
Methods: Fundamental understanding...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, Humberto Monsivais, John Rong
Affiliation: Purdue University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To investigate the noise characteristics of a clinical photon counting detector CT (PCD-CT) system along axial and through-plane (Z) dimensions using 3D NPS measurements.
Methods: This stu...
Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose: To precisely detect intrafraction patient motion during spine stereotactic body radiotherapy (SBRT) treatment delivery, we propose an optimized technique for three-dimensional reconstruction ...
Authors: Liang-Hsin Chen, Li-Chien Wei
Affiliation: National Taiwan University Cancer Center
Abstract Preview: Purpose: For proton therapy treatment, it is essential to ensure that the treatments are delivered safely and accurately. Quality assurance (QA) programs of proton treatment system is needed and proto...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...
Authors: Liang-Hsin Chen, Hsiang-Kuang Tony Linag
Affiliation: National Taiwan University Cancer Center, Department of Biomedical Engineering, National Taiwan University
Abstract Preview: Purpose: The characteristics of scanning proton beam is one of crucial factors to affect dose delivering accuracy in proton theray. Therefore, this study aims to evaluate and monitor the stability of ...
Authors: Kazi Towmim Afrin, Imad M. Ali, Jordan West
Affiliation: University of Oklahoma Health Sciences Center, University of Oklahoma
Abstract Preview: Purpose: To simulate total-body-irradiation (TBI) with field-in-field treatment planning techniques and test portal dosimetry for dose verification and quality assurance.
Methods: CT images of full...
Authors: Aditya P. Apte, Joseph O. Deasy, Yusuf Emre Erdi, Anqi Fu, Johannes Hertrich, Andrew Jackson, Usman Mahmood, Jason Ocana, Trahan Sean, Amita Shukla-Dave
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Automated AI-based quantitative CT tools hold immense promise for advancing clinical decision-making, yet their reproducibility and generalizability remain vulnerable to variability in imagin...
Authors: Zijia Guo, Viktor Haase, Michael F. McNitt-Gray, Frederic Noo
Affiliation: Siemens Healthineers, University of Utah, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: The attenuation values in CT hold strong potential for disease diagnosis. However, they lack reliability, which has limited their use to clinical trials where variability can be controlled. S...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...
Authors: Darren Fang, Amar Kishan, Justin McWilliams, Dan Ruan, Xiaodong Zhong
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Department of Radiological Sciences, University of California, Los Angeles
Abstract Preview: Purpose: Prostate radiotherapy can malform penile vasculature, contributing to erectile dysfunction and compromising quality of life. To detect, quantify, and preferably avoid such occurrences, this p...
Authors: Jing Qian, Brandon Reber, David M. Routman, Satomi Shiraishi
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The dose distribution in proton radiotherapy (PRT) is characterized by sharp gradients, posing a challenge for machine learning-based dose prediction. While denoising with diffusion processes...
Authors: Rebecca Lamoureux, Zahra (Zara) Razi, Zachary Whipps
Affiliation: University of New Mexico Hospital
Abstract Preview: Purpose: Patient mispositioning in CT imaging contributes to inconsistent radiation dose delivery and suboptimal image quality, impacting patient safety and diagnostic outcomes. This study evaluates a...
Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang
Affiliation: RefleXion Medical
Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...
Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk
Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center
Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...
Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...
Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.
Methods: A commercial rotational table (CDR EquilibriumÂź) is r...
Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai
Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...
Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Demonstrating the feasibility of dose escalation for stereotactic recurrent head and neck (RHN) cancers through the deployment of a Hyper-Arc Based RapidPlan (HARP) model through an Eclipse S...
Authors: Owen Thomas Dillon, Andrew Kanawati, Tess Reynolds
Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Metal artefacts from implanted hardware and surgical tools remain a limitation for widespread adoption of intraoperative CBCT imaging. Gantry-based non-circular imaging trajectories have emer...
Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...
Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din
Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University
Abstract Preview: Purpose: Accurate, efficient, and reliable commissioning of linear accelerator (LINAC) is critical for ensuring high-quality radiation therapy treatments. The study uses advanced detector technology a...
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Active breath-hold techniques effectively mitigate respiratory motion but poses challenges for patients who are unable to tolerate the procedure. Conventional planning relies on multiple ener...
Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh
Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.
Methods: Two ultrasonic transducers position...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Renxin Chu, Jelena Mihailovic, Kai Yang, Lifeng Yu, Da Zhang
Affiliation: Massachusetts General Hospital, Mayo Clinic, Boston Children's Hospital, UVA Health University Hospital, University of Missouri Health Care
Abstract Preview: Purpose:
A frequently used method to estimate effective dose (ED) in CT is by multiplying the dose length product (DLP) by a conversion factor, known as k-factor. The k-factor in this method is sus...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Ming Dong, Carri K. Glide-Hurst, Behzad Hejrati, Joshua Pan, Yuhao Yan
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright patient positioners and vertical CT reduce tumor motion and stabilize internal anatomy during treatment delivery. Yet, to fully exploit the advantages of upright, translation of stand...
Authors: Clara Ferreira, Tomas Agustin Montenegro, Courtney C. Oare
Affiliation: University of Minnesota
Abstract Preview: Purpose: This work provides a simulated proof of concept for the use of intravitreal gold nanoparticle (AuNP) during eye plaque brachytherapy as a radiation shield to critical structures in the eye us...
Authors: Ibtisam Almajnooni, Siyong Kim, Nathaniel Miller, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: Radiation-induced esophagitis (RE) is a common concern in lung cancer IMRT. Recent studies have indicated that the risk of radiation side effects varies greatly with patientsâ baseline clinic...
Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija
Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging
Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...
Authors: Jie Hu, Nan Li, Chuanbin Xie, Shouping Xu, Xinlei Xu, Gaolong Zhang, Zhilei Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, the First Medical Center of the People's Liberation Army General Hospital, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleÊŒs Republic of China, Department of Radiation Oncology, School of Physics, Beihang University, Beijing, 102206, PeopleÊŒs Republic of China
Abstract Preview: Purpose: This study aims to synthesize CT images for MRI-only radiation therapy using a deep learning approach that integrates information from the T1- and T2-weighted MRI sequence.
Methods: 97 hea...
Authors: Shira Abraham, Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Phillip G. Lichtenwalner, Chuan Zeng, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
We have developed a tool that uses deformable image registrations to perform deformable dose accumulation. In this work we evaluate use of this tool for adaptive head and neck dose accumul...
Authors: Chingyun Cheng, Ben Durkee, Carri K. Glide-Hurst, Minglei Kang, Haibo Lin, Bhudatt R. Paliwal, Charles B. Simone, Zhizhen Wei, Tengda Zhang, Xingyi Zhao
Affiliation: University of Wisconsin, Department of Mechanical Engineering, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Transmission Beam (TB), Single-Energy Bragg Peak (SEBP), and Single-Energy Spread-Out Bragg Peak (SESOBP) are primary proton conformal FLASH techniques. However, each comes with significant l...
Authors: Yi An, David J. Carlson, Zhe (Jay) Chen, Jun Deng, Dae Yup Han, Sameer Taneja
Affiliation: Yale School of Medicine, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Spine Stereotactic radiosurgery (SSR) delivers a large radiation dose and utilizes narrow PTV margins, on the order of 1 mm, to avoid excess dose to the spinal cord. Because of this, intrafra...
Authors: Jiankui Yuan, Dandan Zheng, Tingliang Zhuang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Rochester, Varian Medical Systems, Advanced Oncology Solutions
Abstract Preview: Purpose: In Monte Carlo (MC) radiation therapy dose calculations, latent variance exists when directly applying phase-space files (PSF) with a finite number of source particles, while the latter is pr...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...
Authors: Minsong Cao, Amar Kishan, Dylan P. O'Connell, Jonathan Pham, Michael Steinberg, Luca F Valle, Michael Xiang
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: To evaluate bladder ultrasound as a surrogate for estimating on-table bladder volume in prostate cancer patients undergoing stereotactic body radiation therapy (SBRT). The study aimed to asse...
Authors: Ara Alexandrian, Jessica Ashford, Jean-Guy Belliveau, Allison Dalton, Nathan Dobranski, Krystal M. Kirby, Garrett M. Pitcher, David E. Solis, Hamlet Spears, Angela M. Stam, Sotirios Stathakis, Jason Stevens, Rodney J. Sullivan, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: To improve retrospective risk analysis in radiation oncology by leveraging Large Language Models (LLMs) to extract richly annotated data from unstructured clinical incident reports.
Method...
Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray
Affiliation: University of California San Diego
Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...
Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Gunjan Kayal, Adam Leon Kesner, Harry Marquis, Juan Camilo Ocampo Ramos, Stefan Wehmeier
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson
Abstract Preview: Purpose: Accurate organ dose estimation in computed tomography (CT) has gained attention due to the increasing global utilization of CT imaging. MIRDct, a specialized CT dosimetry software, has recent...
Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison
Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...
Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...
Authors: Min Cheol Han, Soorim Han, Chan Hyeong Kim, Jin Sung Kim, Seok-Ho Lee, Gahee Son, Yongdo Yun
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The stoichiometric calibration method proposed by Kanematsu et al. (2016) has been widely adopted for CT number to stopping-power ratio (SPR) conversion in carbon-ion radiotherapy. With the r...
Authors: Dong Wook Kim, Jin Sung Kim, Dongho Lee, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
Abstract Preview: Purpose:
This study aims to analyze the characteristics of a novel detector based on a dielectric layer (Vieworks Co., Korea), which demonstrates high tolerance to high radiation doses and light tr...
Authors: Farhad Jafari, Brandon Hai Nguyen
Affiliation: Department of Radiation Oncology, University of Minnesota Medical School, Department of Radiology, University of Minnesota
Abstract Preview: Purpose: To validate a bottom-up approach to dosimetry in nuclear medicine.
Methods: A pharmacokinetic model is developed to represent the flow of activity between different compartments of the...
Authors: Naruomi Akino, Kirsten Lee Boedeker, Ilmar Hein, Akira Nishikori, Daniel W Shin
Affiliation: Canon Medical Systems Corporation, Canon Medical Research USA
Abstract Preview: Purpose: To validate a simulation tool using physics-based image quality metrics in both phantom and patient data, and to assess the low contrast detectability (LCD) of Super Resolution-Deep Learning ...
Authors: Michael Evan Chaga, Timothy Chen, Shabbar Danish, Jesse Feng, Joseph Hanley, Georg A. Weidlich
Affiliation: Zap Surgical, Tenafly High School, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the validation of ZapMU for independent check of dose calculation is performed, ut...
Authors: Jean-Pierre Bissonnette, Catherine Coolens, Laura Dawson, Ryan A Kuhn, Michael Maddalena, Teo Stanescu
Affiliation: Princess Margaret Hospital, The Princess Margaret Cancer Centre - UHN, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To investigate the generation and reproducibility of 3D hypoxia maps in liver hepatocellular carcinoma (HCC) patients using data derived from an Intravoxel Incoherent Motion (IVIM) MR sequenc...
Authors: Klaus Bacher, Louise D'hondt, Jeff Rutten, Gwenny Verfaillie
Affiliation: Ghent University
Abstract Preview: Purpose: Manual organ segmentation is a very time-consuming but necessary process in personalized dosimetry. Automatic segmentation tools may alleviate this task. In this study the impact of automatic...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: To quantity variations in Winston Lutz (WL) test results due to different energies used in SBRT, SRT or SRS.
Methods: A WL phantom with a 6.4 mm diameter center radio-opaque sphere is used...
Authors: Harold Y Hu, Yanle Hu, Shuai Leng, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Basis Scottsdale, Mayo Clinic
Abstract Preview: Purpose: Radiotherapy CT simulation often requires two scans: a non-contrast scan for dose calculation and a contrast-enhanced scan for target delineation. Photon-counting-detector (PCD) CT allows the...
Authors: Go Akamatsu, Hiroaki Ikawa, Yuma Iwao, Han Gyu Kang, Masashi Koto, Hideyuki Mizuno, Akram Mohammadi, Makoto Shinoto, Minoru Tajiri, Hideaki Tashima, Chie Toramatsu, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In-beam positron emission tomography (PET), in which positron emitters produced through fragmentation reactions are visualized, is a practical method for range verification in particle therap...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Rama Bhawani, Mary Joan, Ajay Katake, Munish Kumar, Chhape Ram, Megha Sharma, Balbir Singh, Vikram Singh
Affiliation: SLBSGMC & HOSPITAL, MOHANDAI OSWAL HOSPITAL, WOCKHARDT HOSPITAL, Christian Medical College and Hospital,, AMERICAN ONCOLOGY INSTITUTE
Abstract Preview: Purpose: This study aims to evaluate the utility of voxel-based radiobiological modelling in assessing IMRT radiotherapy treatment plans concerning radiation-induced acute mucosal toxicity, specifical...
Authors: Duncan Henry Bohannon, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
4D robust optimization, incorporating additional images (e.g., maximum inhale/exhale phases), is commonly used to account for target motion in proton treatment planning. However, the incre...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...
Authors: Kristy K. Brock, Austin Castelo, Yulun He, Zhongxing Liao, Rebecca Lim, Radhe Mohan, Caleb O'Connor, Tien T Tang, Uwe Titt
Affiliation: University of Washington, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Conformal dose distributions in proton radiotherapy promise to reduce normal tissue toxicity such as radiation-induced pneumonitis, but this has not been fully realized in clinical trials. To...
Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...
Authors: Kenny Guida, Daniel Johnson, Wesley Tucker
Affiliation: University of Kansas Medical Center, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) has emerged as a standard of care for unilateral head and neck (HN) cancers due to superior OAR sparing. With the increase of proton centers national...
Authors: Michael B. Altman, Sharbacha Edward, Jose L. Garcia Ramirez, Anamaria Guta, Elizabeth Gaines Jeong, Justin K. Mikell, Phillip D. H. Wall, Jacqueline Esthappan Zoberi
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: Modern HDR remote afterloaders (RAL) are equipped with enhanced safety features for accurate source positioning. However, little guidance is provided on the use of these features. We have cli...
Authors: Steve B. Jiang, Ruiqi Li, Hua-Chieh Shao, Kenneth Westover, You Zhang, Tingliang Zhuang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Respiratory motion is a long-standing challenge for lung SBRT, particularly for centrally-located lung tumors where increased toxicity demands more precise motion management during treatme...
Authors: Petr Bruza, Megan Clark, David J. Gladstone, Lesley A Jarvis, Allison Matous
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: In vivo dosimetry (IVD) is underutilized, in part, because measured point doses cannot be accurately localized to the patient or treatment planning system (TPS), complicating the clinical and...