Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Sixue Dong, Weigang Hu, Jiazhou Wang, Zhen Zhang
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the dosimetric benefits and treatment efficiency of different beam configurations in 4Ï non-coplanar VMAT for SBRT in recurrent head and neck tumors
Method...
Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr
Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...
Authors: Nebi Demez, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Treatment plans on the ViewRay MRIdian are often planned with the target placed off isocenter due to the proximity of the bore to the patient, allowing for limited shifts. This is especially ...
Authors: Rex A. Cardan, Richard A. Popple
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose:
Compliance with TG 263 naming conventions for target structures in radiation oncology remains a challenging task due to the complexity and variability of the protocol. Traditional validati...
Authors: Yunxiang Li, Hua-Chieh Shao, Chenyang Shen, Jing Wang, Jiacheng Xie, Shunyu Yan, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate liver deformable motion tracking is essential in image-guided radiotherapy to enable precise tumor targeting during treatment. We developed a conditional point cloud diffusion model ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: A challenge for dual energy CBCT is that noise and residual errors in material decomposition steps can become amplified when forming low energy, high contrast virtual mono-energetic images (V...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Gregory Szalkowski, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Respiratory motion management is crucial for accurate radiation delivery to moving targets while protecting healthy tissue, relying on time-resolved volumetric imaging and continuous deformab...
Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Jamieson Baker, Emel Calugaru, Yijian Cao, Jenghwa Chang, Jessica Jung, Jian Liu, Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke
Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health, Hofstra University Medical Physics Program
Abstract Preview: Purpose: Our hospital network has options to treat recurrent glioblastoma (GBM) with surgically targeted Cesium-131 brachytherapy, external beam stereotactic radiotherapy (SRT) with Varian TrueBeam, H...
Authors: Chin-Cheng Chen, Chia-Ho Hua, Christopher J. Kutyreff, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: A dosimetric study was conducted to determine the optimal field parameters for a commercially available small-field applicator (SFA) used in spot-scanning proton stereotactic radiosurgery, pa...
Authors: Yidong Yang, Haolin Zhan
Affiliation: Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop a fast low-dose method for beam blocker-based CBCT scatter correction and evaluate image quality in phantom study.
Methods: The full number of scatter projections were collected...
Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...
Authors: Benito De Celis Alonso, Braian Adair Maldonado Luna, Gerardo Uriel Perez Rojas, RenĂ© Eduardo RodrĂguez-PĂ©rez, Kamal Singhrao
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla
Abstract Preview: Purpose: Artificial Intelligence (AI)-generated synthetic CT (sCT) images can be used to provide electron densities for dose calculation for online adaptive MRI-guided stereotactic body radiotherapy (...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2Dâ3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...
Authors: Timothy J Allen, David A. Sterling
Affiliation: University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Treatment planning for the Venezia HDR brachytherapy applicator is often performed using inverse planning tools such as IPSA or HIPO. However, there are planners who are either unfamiliar wit...
Authors: Beth M. Beadle, Adrian Celaya, Laurence Edward Court, David Fuentes, Anna Lee, Tze Yee Lim, Dragan Mirkovic, Amy Moreno, Raymond Mumme, Tucker J. Netherton, Callistus M. Nguyen, Jaganathan A Parameshwaran, Jack Phan, Carlos Sjogreen, Sara L. Thrower, Congjun Wang, He C. Wang, Xin Wang
Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, Stanford University, The University of Texas MD Anderson Cancer Center, MD Anderson Cancer Center, MD Anderson, Rice University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Quality assurance of target volumes from radiotherapy clinical trials is a labor and resource intensive task. The purpose of this work is to quantify the accuracy of a tool that automatically...
Authors: Edward D. Brandner, Weihua Fu, M. Saiful Huq, Ronald John Lalonde, Kiran Mehta, Hima Bindu Musunuru, Yongqian Zhang
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pittsburgh School of Medicine and UPMC Hillman CancerCenter
Abstract Preview: Purpose: Treatment of diffuse and extensive involvement of the skull by malignancy presents a difficult challenge for radiation therapy. This study reports preliminary experience of a modified volumet...
Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...
Authors: Katelyn M. Atkins, Indrin J. Chetty, Elizabeth M. McKenzie, Taman Upadhaya, Samuel C. Zhang
Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center
Abstract Preview: Purpose:
We explored a multi-regional and multi-omics approach to extract CT-based radiomics and 3D dosiomics features to predict radiation pneumonitis (RP) in patients with locally advanced Non-Sm...
Authors: Louis Archambault, Luc Beaulieu, Alexis Horik, Sajjad Ahmad Khan
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de physique, de génie physique et d'optique, Université Laval
Abstract Preview: Purpose: This study presents a novel 2D scintillation dosimeter leveraging long scintillating fibers for quality assurance (QA) in radiotherapy. The primary goal is to optimize critical parameters suc...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Dale W. Litzenberg, Ikechi S Ozoemelam, Rowan Paplanus, Michael Pillainayagam, Donald A. Roberts
Affiliation: University of Michigan, Oregon Health & Science University
Abstract Preview: Purpose: Clinical linear accelerators use dual foil scattering systems designed to achieve large uniform fields (up to 25Ă25cmÂČ), which can reduce beam fluence by up to 93% compared to the unmodified ...
Authors: James Robert Castle, Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: We propose a novel methodology for lattice deployment in spatially fractionated radiotherapy (SFRT), using principal component analysis (PCA) to improve sphere packing within the tumor. Impro...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Ivan L. Cordrey, Dharmin D. Desai
Affiliation: Cumberland Medical Center - Cancer Center, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: For larger PTVs, VMAT optimizations performed within Eclipse often generate SRS plans with widely scattered hotspots distributed around the inner edge of the PTV â the âring of fire.â This pr...
Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao
Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...
Authors: Benjamin W. Maloney, Ashley E. Rubinstein, Colin Schaeffer, Justin Yu
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Radiography AEC systems ensure correctly exposed images for varied kVp and patient thicknesses. The specific kVp and PMMA thicknesses selected for testing AEC tracking may affect passing rate...
Authors: Liu Hong, Wen C. Hsi, Faraz Kalantari, Romy Megahed, Ganesh Narayanasamy, Maida Ranjbar, Pouya Sabouri, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: Quantitative apparent diffusion coefficients (ADC) in diffusion-weighted MRI (dMRI) reflect water diffusivity and thus provide tissue cellular density information. Functional diffusion mappin...
Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...
Authors: Neil A. Kirby, Parker New, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz
Affiliation: UT Health San Antonio
Abstract Preview: Purpose: To simplify the traditional method of patient-specific skin collimation and improve the precision of electron radiotherapy treatment with a new surface conforming collimation system.
Metho...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Giovanni Iacca, Gloria Miori, Laura Orsingher, Daniele Ravanelli, Annalisa Trianni
Affiliation: Department of Information Engineering and Computer Science, University of Trento, Medical Physics Department, S.Chiara Hospital, APSS
Abstract Preview: Purpose: This study aims to leverage artificial intelligence (AI) to predict and identify performance degradation in Digital Radiography (DR) systems, enabling proactive maintenance and minimizing cli...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...
Authors: Amir Abdollahi, Oliver JĂ€kel, Maxmillian Knoll, Rakshana Murugan, Adithya Raman, Patrick Salome
Affiliation: UKHD & DKFZ, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), German Cancer Research Centre(DKFZ), DKFZ, MGH
Abstract Preview: Purpose:
Missing MRI sequences, due to technical issues in data handling or clinical constraints like contrast agent intolerance, limit the use of medical imaging datasets in computational analysis...
Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Bangho Shin, Yitian Wang
Affiliation: University of Florida
Abstract Preview: Purpose: The skeleton plays a critical role in dosimetry, containing red bone marrow (RBM) and bone endosteum (BE), which are closely linked to radiation-induced leukemia and bone cancer. While severa...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Himanshu Joshi, Tian Liu, Deborah C Marshall, Joseph Shelton, Jing Wang, Xiaofeng Yang, Emi Yoshida, Boran Zhou
Affiliation: Department of Radiation Oncology, Baylor College of Medicine, Icahn School of Medicine at Mount Sinai, Emory University, Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, University of California, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Radiation-induced long-term toxicities, such as vaginal stenosis, significantly impact the quality of life for patients undergoing pelvic radiotherapy (RT) for gynecologic (GYN) malignancies....
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou Peopleâs Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleÊŒs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Josephine Chen, CheukKai Becket Hui, Yildirim D. Mutaf
Affiliation: Kaiser Permanente
Abstract Preview: Purpose:
To demonstrate the effectiveness of a target clustering program in generating cluster configurations and isocenter placements for multiple brain lesions in SRS treatment planning, with the...
Authors: Harsh Arya, Yan Chang, Yujie Chi, Varghese Anto Chirayath, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: In targeted alpha therapy (TAT), absorbed dose rates can vary significantly spatially and temporally, impacting therapeutic efficacy as well as carcinogenic potential. This study reports the ...
Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...
Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...
Authors: Peter Balogh, Wesley E. Bolch, Mir Md Nasim Hossain, Nien-Wen Hu, Walter Murfee, Wyatt Smither, Julia D. Withrow
Affiliation: New Jersey Institute of Technology, University of Florida
Abstract Preview: Purpose: To develop 3D computational, tissue-representative models incorporating physiologically relevant microvascular network patterns for calculating local alpha particle and electron dosimetry eff...
Authors: Olivier Blasi, Eric Cameron, Brad K. Lofton
Affiliation: CAMP, Colorado Assn in Medical Phys (CAMP)
Abstract Preview: Purpose:
Magnetic Resonance (MR) imaging obtained from external centers for radiation therapy (RT) planning can suffer from suboptimal protocols and geometric distortions. These issues can require ...
Authors: Anna Becker, Tomislav Bokulic, Mauro Carrara, Krzysztof Chelminski, Larry A. DeWerd, Alexis Dimitriadis, Benjamin Kellogg, Malcolm R. McEwen, Zakithi L.M Msimang, Mark J. Rivard, Thorsten Sander, Thorsten Schneider, Jamema Swamidas, Egor Titovich, Paula Toroi, Carlos E. de Almeida, Jacco de Pooter, Liset de la Fuente Rosales, Deborah G. van der Merwe
Affiliation: Radiation and Nuclear Safety Authority, University of Zagreb, National Physical Laboratory, IAEA, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Rio de Janeiro State University, Dosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Physikalisch-Technische Bundesanstalt, National Metrology Institute, University of the Witwatersrand, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, National Research Council, Warren Alpert Medical School of Brown University
Abstract Preview: Purpose: The recently published IAEA-TRS-492 international code of practice (CoP) aims at improving traceability, accuracy, and consistency in Brachytherapy Dosimetry. To assess current approaches to ...
Authors: James R Duncan, Nikhat Fatima Mansoori, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Collimation during fluoroscopically-guided interventions (FGIs) can not only reduce radiation exposure to patients and personnel but also improve image quality. Nonetheless, there are concern...
Authors: Ashley Cetnar, Lin Ding, Jeffrey E. Woollard
Affiliation: The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: A cohort of middle school and high school science teachers were selected to learn about physics in medicine, develop lesson plans for their students, participate in a Physics in Medicine fiel...
Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...
Authors: Sarah A. Ashmeg, Travis James McCaw, Joseph Shields, Matthew Spector, Christopher Tyerech, Christopher T Wilke
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: Patients with oral cavity cancer often undergo surgical extirpation prior to radiation, and surgical implants are utilized to reconstruct the resulting defect. This study dosimetrically evalu...
Authors: Xinhua Li, Vu Nguyen, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Assessing iodine concentration in liver lesions is essential for evaluating contrast enhancement in multi-phase liver CT and for accurate disease diagnosis. This study aims to evaluate the as...
Authors: Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Nancy Y Lee, Anyi Li, Jung Hun Oh, Teeradon Treechairusame, Pengpeng Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To automatically monitor weekly anatomical changes of parotid glands during adaptive radiotherapy of head and neck cancers, systematically assess the relationship between parotid gland shrink...
Authors: Maria F. Chan, Seng Boh Gary Lim, Shih-Chi Lin, Dustin W. Lynch, Usman Mahmood, Jeonghoon Park
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To explore the feasibility of using GafChromic LD-V1 film for annual imaging dose assessment across kV radiography, fluoroscopy, and cone beam computed tomography (CBCT) imaging protocols, as...
Authors: Justus Adamson, Wesley Andrew Cunningham, Caleb Logan Smith
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: Radiation induced bowel toxicity is a persistent issue for abdominal Stereotactic Body Radiation Therapy (SBRT). Remote magnetic navigation systems (RMNS) have been developed for use in magne...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Srinivas Cheenu Kappadath, James Long, Armeen Mahvash, Anna Marks, Ajalaya Teyateeti
Affiliation: Mahidol University, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Alpha-fetoprotein (AFP) has been implicated as prognostic factor of overall survival (OS) for hepatocellular carcinoma (HCC). We present a statistical approach to determine optimal AFP-cut...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose:
Pancreatic cancer poses therapeutic challenges due to the proximity of critical organs, requiring precise radiotherapy. Magnetic resonance (MR)-guided linear accelerators provide daily ima...
Authors: Izabella L. Barreto, Aroon Pressram
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Our clinical dual energy CT (DECT) head protocol reconstructs iodine-suppressed virtual non-contrast (VNC) images using the vendor-recommended slope for material discrimination. However, this...
Authors: Derek Matthew Garcia, Mallory Glenn, Stephen F. Kry, Ruitao Lin, Dennis S. Mackin, Tucker J. Netherton
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texasâ MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: This study aims to investigate the feasibility of implementing clinically relevant quality metrics for evaluating IROC SRS phantom plans, including conformity index (CI) and homogeneity index...
Authors: David Alejandro Collazos Burbano, Antonio Adilton Oliveira Carneiro, Paul L. Carson, Jose Eduardo Freire, Theo Zeferino Pavan, Joao Henrique Uliana, Nicholas Zufelato
Affiliation: University of SĂŁo Paulo, University of Michigan, University of Sao Paulo
Abstract Preview: Purpose: Develop a theranostic platform that integrates magnetic hyperthermia (MH), ultrasound, and magnetic nanoparticles (MNPs) to improve diagnosis, treatment, and monitoring of hyperthermia proced...
Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington
Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...
Authors: Yuemeng Feng, Hamid Sabet
Affiliation: Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: We propose a novel brain-dedicated PET system comprising elliptical cylinder with a neck cut-out, supplemented by front and back panels to improve sensitivity and line-of-response sampling. T...
Authors: Jon Hansen
Affiliation: Washington University in St Louis
Abstract Preview: Purpose: Commercially available auto-segmentation software was utilized to generate institution-specific optimization structures for spine stereotactic body radiation therapy (SBRT). Implementation of...
Authors: Beth Bradshaw Ghavidel, Benyamin Khajetash, Yang Lei, Meysam Tavakoli
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Emory University, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose: Pancreatic cancer is among the most aggressive types of cancer, with a five-year survival rate of approximately 10%. Recent studies show that radiomics and deep learning (DL)-based methods ar...
Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi
Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals
Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...
Authors: Maria Jose Almada, Bruno Forti, Andres Lima, Carlos Daniel Venencia
Affiliation: Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
To automate the planning of radiotherapy treatments for bone metastases using a script in the ECLIPSE planning system version 15.6 with a graphical interface.
Methods:
A script was d...
Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos
Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen
Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...
Authors: Hua-Chieh Shao, Chenyang Shen, Jiacheng Xie, Shunyu Yan, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Motion-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection), is highly desired for regular/irregular motion chara...
Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti
Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging
Abstract Preview: Purpose: We characterized the sensitivity, energy dependence, and calibrated dose rate for a radiation imaging survey meter (RAVIN Cam; M3d inc., Ann Arbor MI) based on cadmium zinc telluride (CZT) cr...
Authors: Md Mainul Abrar, Harsh Arya, Yujie Chi, Yijing Liu, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, The University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Understanding the biological effects of alpha radiation at varying dose rates and energies is essential for advancing therapeutic strategies. This study demonstrates the capabilities of an in...
Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania
Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...
Authors: David J. Gladstone, P. Jack Hoopes, David I Hunter, Brian W Pogue, Jacob Pierce Sunnerberg, Armin Tavakkoli
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Geisel School of Medicine, Dartmouth College
Abstract Preview: Purpose: The FLASH effect, characterized by normal tissue sparing under ultra-high dose rate (UHDR) radiation delivery, remains mechanistically unclear. This study investigated the relationship betwee...
Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou
Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, Peopleâs Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial Peopleâs Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital
Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...
Authors: Julien Bancheri, Chau Giang Bui, Christopher M Lund, Morgan J Maher, Jamiel Nasser, Amy Parent, Monica Serban, Jan P. Seuntjens, Jason Z Yuan
Affiliation: University of Toronto, Medical Physics Unit, McGill University, Princess Margaret Cancer Centre, Princess Margaret Cancer Centre & University of Toronto
Abstract Preview: Purpose: Proton therapy (PT) has demonstrated greater precision and superior healthy tissue sparing compared to photon radiotherapy for various sites; however, PT systems are expensive, which limits g...
Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center
Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...
Authors: Wilfred R Furtado, Gary Y. Ge, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: The United Kingdom and several other countries already have well-established diagnostic reference levels (DRLs) for gastrointestinal fluoroscopic procedures, whereas the United States does no...
Authors: Casey E. Bojechko, Lance C Moore
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: EPID images collected during treatment can serve as an in-vivo error detection mechanism. Previous works have shown that comparing in-vivo EPID images to AI-predicted EPID images for IMRT pla...
Authors: Cem Dede, Clifton David Fuller, Renjie He, Laia Humbert Vidan, Stephen Y. Lai, Amy Moreno, Mohamed Naser, Kareem Abdul Wahid, Natalie A West
Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Head and neck cancers (HNC) treated with radiation therapy can result in radiation-induced bone injury. In CT, changes in radiodensity correlate to changes in bone integrity. Most studies use...
Authors: Yingxuan Chen, Jun Li, Alexis N. Webb
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Cone-beam computed-tomography (CBCT) is widely used for image-guided therapy. Cumulative dose from repeated CBCT might be a concern. This study aims to measure and compare the CBCT dose for c...
Authors: Ashok Bhandari, Kurtis Johnson, Yu Lei, Tianzhe Li, Kyuhak Oh, Shuo Wang, Chi Zhang, Su-Min Zhou
Affiliation: University of Nebraska Medical Center
Abstract Preview: Purpose: The purpose of this study was to leverage neural network visualization tools to detect high-attention areas indicative of treatment failure in lung SBRT by examining correlation matrices betw...
Authors: Sophie Boisbouvier, David Cobben, Anthony L Criscuolo, Michael W. Kissick, Mark Ramtohul, Gordon Sands, Tracy Underwood
Affiliation: University of Surrey, Department of Medical Physics, Queen Elizabeth Hospital, Lung Cancer and Sarcoma Radiotherapy, The Clatterbridge Cancer Centre, Leo Cancer Care, Radiotherapy department, Centre LĂ©on BĂ©rard
Abstract Preview: Purpose:
Pulmonary function tests (PFTs) help assess treatment options for lung cancer patients. Conventionally, these are undertaken upright, whereas radiotherapy is administered supine. This stud...
Authors: Ronald C Chen, Hao Gao, Nicolas Gerard, Harold Li, Yuting Lin, Jarrick Nys, Jufri Setianegara, Mark Szczepanski, Aoxiang Wang
Affiliation: 4Physikalisch-Technische WerkstÀtten (PTW), Department of Biomedical Engineering, Huazhong University of Science and Technology, Ion Beam Applications (IBA), Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Modern synchrocyclotrons can produce magnetically-scanned protons at ultra-high dose-rates (FLASH). However, their pulsed nature leads to high doses-per-pulse (DPP) which can cause non-neglig...
Authors: E Courtney Henry, Srinivas Cheenu Kappadath, Armeen Mahvash
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Characterization of hepatocellular carcinoma (HCC) tumor responses for single-arm single-center prospective 90Y-radioembolization clinical trial (n=40) that used patient-specific voxel-dos...
Authors: Mohamad Ahmad Alissa, Carson Brame, Damian Czarnecki, Olivier Evrard, Charbel A. Habib, Jeff Hildreth, Andy Murray, Andreas Schönfeld, Ann-Britt Schönfeld, David Towle, Gerd Wessing
Affiliation: CDT-West - Centrum fĂŒr Diagnostik und Therapie, Radiologie Vechta, Technische Hochschule Mittelhessen, MyMichigan Health, Sun Nuclear Corp., Mirion Technologies
Abstract Preview: Purpose: To characterize the performance of novel shielded and unshielded silicon diode detectors in relative photon and electron beam dosimetry.
Methods: The novel shielded and unshielded sili...
Authors: Brett G Erickson, Joseph P. Kowalski, Xinyi Li, Qiuwen Wu, Sua Yoo
Affiliation: Duke University, Mayo Clinic - Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: Characterization and commissioning of the BeO-based myOSLchip system was performed (per TG191) to assess its feasibility as a full replacement for the recalled Landauer aluminum oxide OSL in ...
Authors: Amar K. Basavatia, Lee C. Goddard, Rachel Grimm, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To characterize the âMyOSL Chipâ OSLD system for clinical use and compare the response of multiple readers to allow for utilization in a multi-clinic environment.
Methods: Dose calibration...
Authors: James Benton, Andrew Dewar, Benjamin C Lee, Ryan Y Lee
Affiliation: Radiotherapy Clinics of Georgia, Urology of Greater Atlanta
Abstract Preview: Purpose:
The purpose of our investigation was to determine if pre-treatment factors could predict urinary morbidity after combination radiation treatment for localized prostate cancer.
Methods:<...
Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: Madeleine Arbogast, David Dorndos, Denise E Foltz, Justin Fraser, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Neurosurgery, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: For stereotactic radiosurgery (SRS) treatments of intracranial arteriovenous malformations (AVM) and fistulas (AVF), same-day Leksell Gamma Knife (GK) is the preferred modality. Long-term cli...
Authors: David L. Barbee, Paulina E. Galavis, Lena Adel Samad, Jose R. Teruel Antolin
Affiliation: NYU, NYU Langone Health
Abstract Preview: Purpose: To validate an automated script that converts treatment plans of varying Varian MLC models
Methods: A C# script was developed using the Eclipse Scripting API to convert treatment plans...
Authors: ISAAC Amoah, Jackie Austin, Charlotte Block, Kaylee Brilz, Dylan Bui, Andrew E. Ekpenyong, Jayce Hughes, Natasha Ratnapradipa, Sara Strom, Jacob Woolf
Affiliation: Creighton University
Abstract Preview: Purpose: Cancers of the brain and nervous system account for 1 in 100 cancer diagnoses in the US every year. Surgery, radiotherapy, and chemotherapy constitute the standard of care. For Glioblastoma (...
Authors: Kimberly Chan, Anke Henning, Mahrshi Jani, Andrew Wright, Xinyu Zhang
Affiliation: Advanced Imaging Research Center (AIRC), UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate the performance of multiple deep learning architectures for MRSI reconstruction and determine their effectiveness in maintaining high-resolution metabolite mapping while reducing ...
Authors: Theodore Higgins Arsenault, Beatriz Guevara, Rojano Kashani, Raymond F. Muzic, Gisele Castro Pereira, Alex T. Price
Affiliation: University Hospitals Seidman Cancer Center, Case Western Reserve University Department of Biomedical Engineering
Abstract Preview: Purpose: Accurate dose prediction in radiotherapy is essential for treatment planning. This study evaluates four nnUnet-based models using the OpenKBP head and neck dataset: a baseline model (Model 1)...
Authors: Chang Heon Choi, Yoonsuk Huh, Jin Jegal, Seonghee Kang, Jung-in Kim, Inbum Lee, Hyojun Park
Affiliation: Department of Radiation Oncology, Seoul National University Hospital
Abstract Preview: Purpose: This study evaluates SpekPy, a Python-based tool for modeling kilovoltage (kV) x-ray spectra, by comparing its calculated energy spectra, half-value layer (HVL), and air kerma with experiment...
Authors: Wenwen Bai
Affiliation: The Fourth Hospital of Hebei Medical University
Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...
Authors: Jonathan J. Chen, Alexei V. Chvetsov, Yulun He, Ramesh Rengan, Andrew Stacey, Kent Wallner
Affiliation: University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To show that the RBE of low-energy photon sources used in COMS (Collaborative Ocular Melanoma Study) eye plaques compensates for protracted irradiation and attenuation of low-energy photons i...
Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...
Authors: Junsheng Cao, Khushdeep Singh
Affiliation: Overlook Medical Center
Abstract Preview: Purpose: Eclipse v18 introduces Enhanced Leaf Modeling for MLCs. This study investigates the MLC off-axis characteristics using portal dosimetry
Methods:
MLC characteristics were analyzed for th...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....
Authors: Krystal M. Kirby, Aliasghar Rohani, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, Louisiana State University, Baton Rouge, Louisiana
Abstract Preview: Purpose: Accurate treatment delivery in MR-guided radiotherapy (MRgRT) systems requires consistent imaging quality assurance (QA) to assess MR image quality. However, standard QA phantoms have limited...
Authors: Tetsuo Fukuda, Hideaki Hirashima, Kohei Kawata, Yukako Kishigami, Takashi Mizowaki, Mitsuhiro Nakamura, Yohei Sawada, Maika Urago
Affiliation: Kyoto University, kyotoUnivercity, Hitachi high-tech, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To present the comprehensive commissioning results of the O-ring shaped linac, OXRAY.
Materials and Methods: OXRAY enables a novel three-dimensional unicursal noncoplanar irradiation metho...
Authors: Ziyad ABUBAKR ALHAREESHi, Ibtihaj Yussef Alhodire, Najla Sobhi Bin Shehima, Aram Mufteh A Genaw
Affiliation: Tripoli university hospital
Abstract Preview: Purpose:
This research investigates the recombination and polarity correcting factors for CC04, CC13, FC65P, FC65G, Razor, and PP05 ionization chambers to improve radiation dosimetry accuracy. Unde...
Authors: Gourav Jhanwar, Mojtaba Tefagh, Masoud Zarepisheh
Affiliation: The University of Edinburgh, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Radiotherapy treatment planning involves solving computationally-intensive and time-consuming optimization problems. Central to these problems is a large matrix known as the dose-influence...
Authors: Baher Elgohari, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Jeonghoon Park, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, UPMC, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
To compare toxicity between consecutive-daily (QD) with every-other-day (QoD) delivery of lung stereotactic-body-radiation (SBRT) for central non-small-cell lung cancer (NSCLC).
Methods...
Authors: Nrusingh C. Biswal, Sally Cheston, Sung-Woo Lee, Weiguang Yao, Baoshe Zhang
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: The deep inspiration breath-hold (DIBH) technique in left breast radiation reduces doses to critical organs such as the heart, left lung, and left anterior descending artery (LAD). With the a...
Authors: Niki Fitousi, Anna Romanyukha, Stuart Utting
Affiliation: University Hospitals Dorset, Qaelum NV
Abstract Preview: Purpose:
For increased patient safety and with a focus on sustainability in the radiology department, efforts are being made to optimize contrast media usage. In this study, the possibility of util...
Authors: Emi Ai Eastman, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Iterative reconstruction (IR) methods are valuable for reducing dose in modern CT; however, IR methods have the effect of reducing spatial resolution and hence the lesion edge sharpness. Furt...
Authors: Abdusalam Abdukerim
Affiliation: Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Coronary computed tomography angiography (CCTA) is the gold-standard non-invasive test for coronary artery disease (CAD), but iodine contrast agents (ICA) pose limitations in specific popu...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study examines the correlation of different dose volume metrics of the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) structures with the skin systemic sclerosis...
Authors: Seung Yeon Kim, Grant A. McAuley, Ju A Park, Jerry D Slater
Affiliation: Loma Linda University
Abstract Preview: Purpose: The production of proton minibeams in standard PBS nozzles is challenging due to the effects of finite source beam divergence and multiple Coulomb scattering. Herein we investigate the use of...
Authors: Afrouz Ataei, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose: Even though many patients undergo diagnostic CT scans prior to treatment, simulation CT scans are commonly required for treatment planning. This study evaluates whether prior diagnostic CT sc...
Authors: Zhuo Chen, Tinsu Pan, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, WashU Medicine, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Misregistration between data-driven gated (DDG)-PET and CT can limit the benefits of motion correction and improved localization and quantitation. DDG-CT offers a solution to these issues. He...
Authors: Ryan Andosca, Peter Boyle, Minji Victoria Kim, Michael Vincent Lauria, Daniel A. Low, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Dylan P. O'Connell, Ricky R Savjani
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, UCLA, University of California, Los Angeles, UCLA Radiation Oncology
Abstract Preview: Purpose: To demonstrate the performance of the model-based CT scanning protocol, 5DCT, as an alternative to 4DCT.
Methods: 5DCT imaging results for 242 patients were analyzed. Implementation of the...
Authors: Yaspal Badyal, Rabten Datsang, Tianjun Ma, William Song
Affiliation: MVision AI, Virginia Commonwealth University
Abstract Preview: Purpose: Deep learning (DL)-based dose distribution predictions for prostate cancer show significant potential for OAR sparing compared to manually optimized treatment plans. We aim to generate clinic...
Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang
Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...
Authors: Gary Y. Ge, Abdullah-Al-Zubaer Imran, Kazi Ramisa Rifa, Charles Mike Weaver, Jie Zhang
Affiliation: University of Kentucky
Abstract Preview: Purpose: With renewed attention on CT radiation dose management following CMS approval of new dose measures, establishing image qualityâbased target doses for every protocol has become essential. Whil...
Authors: Zixu Guan, Takahiro Iwai, Takashi Mizowaki, Mitsuhiro Nakamura, Michio Yoshimura
Affiliation: Kyoto University, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose:
The goal of this study is to develop a fully automated treatment planning approach for VMAT in pancreatic cancer that can convert patient anatomy into LINAC machine parameters. In this wor...
Authors: Chih-Wei Chang, Runyu Jiang, Mark Korpics, Yuan Shao, Aranee Sivananthan, Zhen Tian, Ralph Weichselbaum, Xiaofeng Yang, Aubrey Zhang, Xiaoman Zhang
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Department of Physics, University of Chicago, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, School of Public Health, University of Illinois Chicago
Abstract Preview: Purpose: Gamma Knife (GK) plan quality can vary significantly among planners, even for cases handled by the same planner. Although plan quality metrics such as coverage, selectivity, and gradient inde...
Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma
Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC
Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...
Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita
Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital
Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...
Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...
Authors: Ahssan Balawi, Peter Jermain, Timothy Kearney, Sonali Rudra, Michael H. Shang, Markus Wells, Mohammad Zarenia
Affiliation: Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: To investigate the applicability and accuracy of a deep learning (DL) model in predicting radiation dose distribution for breast cancer patients treated with pencil-beam-scanning proton radio...
Authors: Xinyi Fu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...
Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic
Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang
Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale
Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Mustafa Bashir, Diana Kadi, Kyle J. Lafata, Jacob A. Macdonald, Mark Martin, Yuqi Wang, Marilyn Yamamoto
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Electrical and Computer Engineering, Duke University, Department of Radiology, Duke Unversity
Abstract Preview: Purpose: To develop a high-throughput, automated-data-interrogation pipeline for integrating imaging and clinical information to identify key determinants of liver volume (LV), enabling population-sca...
Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...
Authors: Chase Cochran, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...
Authors: Md. Jobairul Islam
Affiliation: Department of Radiation Oncology, Labaid Cancer Hospital and Super Speciality Centre
Abstract Preview: Purpose: Electron radiotherapy is an effective treatment for superficial tumors but requires field-shaping devices like electron applicators, which are labor-intensive to produce. This study aimed to ...
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Childrenâs Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Childrenâs Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Childrenâs Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Alejandro Bertolet, Isaac Meyer, Harald Paganetti, Jan PO Schuemann, Wook-Geun Shin
Affiliation: Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a methodology for Monte Carlo modeling of cell-specific DNA geometries based on Hi-C data using TOPAS-nBio, and to evaluate early DNA damage distributions.
Methods: Hi-C data of...
Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda
Affiliation: McMaster University
Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...
Authors: Kaelyn Becker, Xenia Ray
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: Ethos 2.0 with HyperSight (Varian Medical Systems) imaging enables nearly fully automated offline adaptive radiotherapy including automated deformation of targets and recalculation on the Hou...
Authors: Somayeh Gholami, Saeedeh Ketabi, Jeremy Kunz, Ali Yousefi
Affiliation: Department of Radiation Oncology, University of Utah, University of Utah, Department of Management- Operations Research, University of Isfahan
Abstract Preview: Purpose: This paper aims to present a novel approach for automatic knowledge-based planning optimization for Intensity Modulated Radiotherapy, along with the two downsizing techniques for improving th...
Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng
Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...
Authors: Huiming Dong, Jonathan Pham, X. Sharon Qi, Ann Raldow
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: The study aimed to investigate longitudinal apparent diffusion coefficient (ADC) as an early biomarker of treatment response in patients with locally advanced rectal cancer (LARC) undergoing ...
Authors: Michael Buckstein, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Inter-fraction anatomic variations in liver SBRT can cause significant discrepancies between planned and delivered doses. We developed a CBCT-based accumulative algorithm to directly compare ...
Authors: Indra J. Das, Ahtesham Ullah Khan, Andrew J. White
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Small field dosimetry presents challenges due to lateral disequilibrium and the selection of suitable detectors. Volume averaging and density corrections hamper accurate profile measurements....
Authors: Ehsan Abadi, Njood Alsaihati, Steven T. Bache, Mridul Bhattarai, Cindy Marie McCabe, Francesco Ria, Ehsan Samei
Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Duke University Health System, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: To compare and contrast alternative methods including reader (in hominum), phantom (in phantasma), in vivo, and in silico methods deployed to assess the performance of photon counting (PCCT) ...
Authors: Xiance Jin
Affiliation: 1st Affiliated Hospital of Wenzhou Medical University
Abstract Preview: Purpose:
Deep learning deformable registration models was proposed to predict optimal dose distributions a with a few of optimal planned doses using a few-shot learning for cervical cancer.
Meth...
Authors: Woong Cho, Jin-Beom Chung, Moo-Jae Han, Sang Won Kang, Boram Lee
Affiliation: Department of Radiation Oncology, Seoul National University Boramae Medical Center, Department of Radiation Oncology, Seoul National University Bundang Hospital, Department of Radiation Oncology, Inha University Hospital
Abstract Preview: Purpose: This study aims to establish a digital quality assurance (QA) system for high-dose-rate (HDR) brachytherapy by evaluating self-developed polycrystalline semiconductor dosimeters (PSDs).
Me...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Michael Leyva, Alejandro Rene Llanes Lopez, William Romaguera, Ranjini P. Tolakanahalli, Deborah Wang
Affiliation: Miami Cancer Institute, Baptist Health South Florida, Miami Cancer Institute, Miami Cancer Institute, Baptist Health
Abstract Preview: Purpose: To evaluate whether a modulated electron bolus (MEB) technique improves both nominal and shifted dose distributions in nasal electron therapy as compared to a nonâmodulated, uniformâthickness...
Authors: Amar K. Basavatia, Sandeepan Ganguly, Lee C. Goddard, Wolfgang A. Tomé
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: To investigate the dosimetric impact of WGTG51-e Report 385, recently updated CoP for clinical electron beams. This study uses a chamber specific effective point of measurement (EPOM) shift t...
Authors: Ahmad Amoush, Adam C. Riegel
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: To investigate the dosimetric differences between the reference CT plan, the scheduled plan, and the adaptive plan for a bladder cancer patient treated with Varian Ethos system.
Methods: A...
Authors: Carlos E. Cardenas, Udbhav S. Ram, Marcin Wierzbicki
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham, Juravinski Cancer Centre
Abstract Preview: Purpose:
This study aims to systematically evaluate the dosimetric properties and delivery efficiency of 6X-FFF and 10X-FFF beams for lung SBRT on the Varian TrueBeam STx using the Eclipse TPS 16.1...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko SalomĂłn Alva SĂĄnchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Min Su
Affiliation: Mount Sinai School of Medicine
Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...
Authors: Lining Chen, Zhitao Dai, Shumei Jia, Yajun Jia, Enzhuo Quan
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen HospitalïŒ Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: This work reviewed 12 patient clinical LRT treatments in physics view including geometric and dosimetric parameters and discussed the pros and cons related to the latter.
Methods: Geometri...
Authors: Makunda Aryal, Gregory Bartlett, David D. Campos, Ke Colin Huang, Sook Kien Ng, Christopher F. Njeh, Oluwaseyi Oderinde, Edwin Quashie, Ashok Tiwari, Yong Yue
Affiliation: Purdue University, Department of Radiation Oncology, Indiana University, Indiana University, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose:
Linear accelerator-based single-isocenter Stereotactic Radiosurgery (SRS) is widely used for treating brain metastases due to its efficiency, reduced treatment time, and lower imaging dose...
Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center
Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...
Authors: Darren Kaplan, Chenguang Liu, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center
Abstract Preview: Purpose: This study evaluates the hypothesis that surface-guided radiation therapy for the breast or chest wall using proton PBS provides comparable target coverage and OARs sparing to x-ray-based IGR...
Authors: Jingying Lin, Stevan Pecic, Strahinja Stojadinovic
Affiliation: University of Belgrade, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: This study aims to determine the magnitude of polarization-induced dosimetric error for EBT4 films at different scanning orientations, and to provide guidance on selecting appropriate regions...
Authors: Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Rojano Kashani, Kyle O'Carroll, Gisele Castro Pereira, Christian Erik Petersen, Alex T. Price, Meiying Xing, Reine abou Zeidane
Affiliation: university hospital, University Hospitals Seidman Cancer Center
Abstract Preview: Purpose:
Experimental data have shown the inconsistent monitor unit and target coverage in Ethos 1.1. This can lead to inaccurate dose delivery, compromising patient safety and treatment outcomes. ...
Authors: Alexei V. Chvetsov, Pavitra Ramesh, Alexei V. Trofimov
Affiliation: Massachusetts General Hospital, University of Washington
Abstract Preview: Purpose: To investigate the effect of dose and depth dependence of relative biological effectiveness (RBE) on hypofractionated proton therapy for ocular melanoma using equivalent uniform RBE-weighted ...
Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington
Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky
Abstract Preview: Purpose: To investigate the effect of variation in the α/ÎČ of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...
Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine
Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study aims to quantify the dose discrepancy associated with improper placement of the Leipzig applicator on the patient's skin.
Methods: Monte Carlo simulations were performed using t...
Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora
Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...
Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...
Authors: Zakaria Aboulbanine, Greeshma A. Agasthya, Paul Inman, Anuj J. Kapadia, Anthony Hong Cheol Lim, Jayasai Ram Rajagopal, Chris C. Wang
Affiliation: Oak Ridge National Laboratory, Georgia Institute of Technology
Abstract Preview: Purpose: Radiobiological simulation via TOPAS-nBio requires significant computational resources and time to provide meaningful results. This study aims to decrease simulation time and computational re...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Gaolong Zhang
Affiliation: Department of Radiation Oncology, School of Physics, Beihang University, School of physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: In intensity-modulated proton therapy (IMPT) for head and neck cancer, CBCT registration ensures accurate setup, minimizing dose errors. Unlike IMRT, IMPT plans directly define tumor volumes ...
Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda
Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina â Gemelli Isola
Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) modelsâdeveloped using Italian breast radiotherapy dataâto a Nepalese hospital, thereby demons...
Authors: Jessica Fagerstrom, Juliana Ama Kplorfia, Abigail N.M. Quaye, Mercy T Schandorf, Bishwambhar Sengupta, Peniel T Twum, Afua A. Yorke
Affiliation: University of Ghana Medical Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Medical Equipment and Ancillary Services, Girls Excellence Movement, Global Communities
Abstract Preview: Purpose: To empower and promote diversity in Science, Technology, Engineering, and Mathematics (STEM), an educational presentation and hands-on session were organized to raise awareness of STEM career...
Authors: Deidre Batchelar, Michael Kudla, Stephanie Merkl, Tony Teke
Affiliation: BC Cancer - Kelowna
Abstract Preview: Purpose: Preplanning 3D-printed templates for cervical and vaginal brachytherapy is an iterative process, often taking hours to for an individual patient.
This study demonstrates an end-to-end auto...
Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...
Authors: Ameer Elaimy, Theodore Lawrence, Charles S. Mayo, Seyyedeh Azar Oliaei Motlagh, Benjamin S. Rosen
Affiliation: University of Michigan
Abstract Preview: Purpose: To analyze the impact of clinical features on short-term survival, toxicity, and poor outcomes in HCC patients treated with SBRT,using automated data aggregation and enhanced algorithms with ...
Authors: Jennifer L. Dolan, Chengyin Li, Parag Parikh, Doris N. Rusu, Kundan S Thind
Affiliation: Henry Ford Health, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The time and resource demands of online Adaptive Radiation Therapy (ART) can limit its widespread clinical adoption and potentially impact patient throughput. To address this, we developed a ...
Authors: David Chighvinadze, Chieh-Wen Liu, Sugandima Weragoda, Ping Xia
Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic
Abstract Preview: Purpose: To explore the feasibility of using coplanar beams with collimator angle optimization for brain SRS plans with Halcyon system.
Methods: This study used a dataset of 26 patients with 2-3 br...
Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda
Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xiâan Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xiâan Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...
Authors: Yang Lei, Haibo Lin, Tian Liu, Charles B. Simone, Shouyi Wei, Ajay Zheng
Affiliation: Icahn School of Medicine at Mount Sinai, New York Proton Center
Abstract Preview: Purpose: Radiation-induced lung injury (RILI), encompassing pneumonitis and fibrosis, represents a critical dose-limiting factor in lung cancer radiation therapy. Variability in treatment outcomes is ...
Authors: Samira Dabaghmanesh, Beth A. Erickson, William Hall, Jason Hirshberg, An Tai
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Treatment plan evaluation for minimizing duodenal toxicity often involves multiple dose-volume constraints that vary based on fractionation. The Equivalent Uniform Dose (EUD) has emerged as a...
Authors: Angel Gomez, Titania Juang, Grace Gwe-Ya Kim, Boyu Meng
Affiliation: UC San Diego, UCSD, University of California San Diego
Abstract Preview: Purpose: Single-Isocenter Multiple Targets (SIMT) Stereotactic Radiosurgery (SRS) is widely used for its precision and effectiveness. However, standardized quality assurance (QA) protocols for SIMT SR...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...
Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...
Authors: Dean Darnell, Iyanna M Lewis, Francesco Ria, William Paul Segars
Affiliation: Duke University, Duke University Medical Physics Graduate Program, Center for Virtual Imaging Trials, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University Medical Center
Abstract Preview: Purpose: To estimate radiation dose to pediatric patients during standard CT imaging of the chest and abdomen and determine how dose varies with patient age, height and weight and how measurements com...
Authors: Christopher G. Ainsley, Pradeep Bhetwal, Yingxuan Chen, Wookjin Choi, Vimal K. Desai, Karen E. Mooney, Adam Mueller, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: MR-guided adaptive radiotherapy (MRgART) has demonstrated improved outcomes for patients with pancreatic cancer. However, the time-consuming re-segmentation of targets and organs-at-risk (OAR...
Authors: Emily Helen Hayes, Chihray Liu
Affiliation: University of Florida
Abstract Preview: Purpose: To evaluate dosimetric discrepancies in bladder dose calculations among rigid, deformed, and manual contouring methods in prostate cancer patients and assess dose variations resulting from bl...
Authors: Nema Bassiri, Kristen A. Duke, Neil A. Kirby, Thomas Wilson Klender, Christien Kluwe, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz, Michelle de Oliveira
Affiliation: Miami Cancer Institute, University of Texas HSC San Antonio, UT Health San Antonio
Abstract Preview: Purpose: Determine the practical usability for three phantoms to be used with the ExacTrac Dynamic thermal imaging system. Thermal-guided imaging can be used for inter and intra motion management, pat...
Authors: Jacob S. Buatti, Kristen A. Duke, Malena Fassnacht, Neil A. Kirby, Parker New, Niko Papanikolaou, Arkajyoti Roy, Yuqing Xia, Michelle de Oliveira
Affiliation: The University of Texas San Antonio, UT Southwestern Medical Center, UT Health San Antonio
Abstract Preview: Purpose:
Quantifying and visualizing uncertainty is critical for building clinical trust in AI-generated dose distributions. This study evaluates Monte Carlo Dropout (MCD), Snapshot Ensemble (SE), ...
Authors: Weiyuan Wang
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose:
This study investigates the variability between popular light meters by measuring mammography review workstation monitors using three calibrated light meters.
Methods:
Three calibrat...
Authors: Ben Archibald-Heeren, Grace Gwe-Ya Kim, Kelly Kisling, Xenia Ray
Affiliation: UC San Diego, Icon Cancer Centres, University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: To evaluate improvements in external beam plans for gynecological cancers from a novel planning solution: RapidArc Dynamic (RAD) (Varian Medical Systems, Palo Alto, CA) which optimizes VMAT w...
Authors: Yi-Fang Wang, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...
Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang
Affiliation: Cincinnati Children's Proton Therapy Center
Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...
Authors: Xiaoyu Duan, Xinyu Hu, Runqiu Li, Xiang Li
Affiliation: Dukekunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose:
Accurate detection of small-sized microcalcifications (ΌCalcs) (< 500 ”m) is critical for early breast cancer diagnosis, requiring optimal imaging systems and reconstruction algorithms. Ho...
Authors: Andrew M Baschnagel, Jonathan W. Engle, Jessica E. Griffin, Gihan Gunaratne, Reinier Hernandez, Randall J Kimple, Aaron M. LeBeau, Natalie Y. Luo, Rachel Minne, Caroline M. Mork, Kwangok P Nickel, Jayden West, Madalynn R. Wopat
Affiliation: University of Wisconsin, University of Wisconsin, Department of Pathology and Laboratory Medicine, Department of Medical Physics, School of Medicine and Public Health, University of WisconsinâMadison, University of Wisconsin - Department of Human Oncology, UW Madison, University of Wisconsin, Department of Medical Physics
Abstract Preview: Purpose: The Mesenchymal-Epithelial Transition gene (MET), a targetable cell surface receptor responsible for stimulating cell growth and proliferation, is altered in approximately 10% of non-small ce...
Authors: Mervat A. Alharbi, Wesley S. Culberson
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Medical Physics Department, School of medicine and Public Health, University of Wisconsin-Madison
Abstract Preview: Purpose: The charge collection using ionization chambers is challenging at ultra-high dose rates (UHDR) due to the high ion recombination The Exradin A30 prototype parallel-plate ion chamber manufactu...
Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao
Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen HospitalïŒ Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patientsâ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...
Authors: Ergun E. Ahunbay, Abdul Kareem Parchur, Eric S. Paulson, Ilaria Rinaldi, Angelo Schiavi, Li Zhao
Affiliation: Sapienza University of Rome, Department of Radiation Oncology (Maastro), GROW School for Oncology, Maastricht University Medical Centre+, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Secondary dose calculations (SDC) facilitate patient-specific quality assurance for online adaptive intensity-modulated proton therapy (IMPT). However, there is currently a lack of commercial...
Authors: Nobukazu Fuwa, Masato Horita, Takahiro Kato, Ryo Tanokura, Yuki Tominaga
Affiliation: Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Central Japan International Medical Center, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University
Abstract Preview: Purpose:
We have installed a new type of scanned proton therapy system (Varian ProBeam 360°TM). This study aimed to evaluate the four different dose calculation algorithms.
Methods:
Sixteen b...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling, Jianling Yuan
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: To analyze volume changes in the high-risk clinical target volume (HR-CTV) during high-dose rate (HDR) brachytherapy for cervical cancer patients. The study aims to evaluate the trend and cor...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Yu-Ying Lin, Yu Chen Shen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...
Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...
Authors: Brian D. Casto, Mathew Y Kang, Lichung Ku, Samuel J Wang, Joseph B. Ying, Walker Ray Zimmerman
Affiliation: Salem Health Cancer Center, Salem Health
Abstract Preview: Purpose: Varian HyperArc is an advanced radiotherapy module designed to efficiently deliver high-quality multi-target stereotactic radiosurgery (SRS) treatment plans on Varian linacs. However, the int...
Authors: Yijian Cao, Jenghwa Chang, Lyu Huang
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose: This study evaluates the treatment delivery efficiency and workflow of two advanced linear accelerator systemsâVarianâs TrueBeam (C-arm) and Halcyon (O-ring)âfor prostate Stereotactic Body Ra...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXionÂź X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Arjit K. Baghwala, Devin J. Olek, Parth K. Patel, Ramiro Pino, Adam Yanez
Affiliation: Houston Methodist Hospital, Kaiser Permanente
Abstract Preview: Purpose: The Halcyon beam model in Eclipse is immutable and only includes output factors (OF) for fields down to 1x1 cm2. The TPS must extrapolate OFs for smaller fields used in stereotactic (SRS/SBRT...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To systematically evaluate the relationship between Activity Concentration (AC) obtained from the RefleXion PET-Linac with the maximum standardized uptake value (SUVmax) derived from a diagno...
Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC
Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyonâs doub...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: Our GammaKnife(GK) has been upgraded from 4C to ICON recently. In this study we evaluated the performance of Lightning IPO for ICON.
Methods: 10 cases with single brain metastasis previous...
Authors: Milad BaradaranGhahfarokhi, Ashley Elizabeth Bonner, James R. Burns, Annie Cooney, George X. Ding, Kenneth L. Homann, Guozhen Luo
Affiliation: Corewell Health William Beaumont University Hospital, Vanderbilt University Medical Center
Abstract Preview: Purpose: The goal of this study was to evaluate the performance of a new plastic scintillating detector (PSD) system with 0.5Ă0.5 mm2 and 1.0Ă1.0 mm2 probes (referred to as Medscint0.5 and Medscint1.0...
Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu
Affiliation: Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: In August 2024, ZAP-X introduced automatic placement for isocenters in a DP-1010 upgrade for treatment planning. In this study, plans made by automatic placed isocenters are compared to those...
Authors: Gweneth Andersen, Colleen M. Foote, David (Bo) McClatchy, Hannah McFarland
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To quantify the impact of MLC model differences and LINAC age on treatment plan evaluation by log file-based patient-specific QA (PSQA) through the lifetime of the machines.
Methods: 3D ga...
Authors: Adnan Jafar, Xun Jia, Michael B. Roumeliotis
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: HDR brachytherapy (HDRBT) treatment planning is challenging due to the need for high-quality plans under time pressure, considering anatomy and applicator geometry. This study proposes an exp...
Authors: Junghoon Lee, Todd R. McNutt, Harry Quon, Bohua Wan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Department of Computer Science, Johns Hopkins University
Abstract Preview: Purpose: Xerostomia is a common toxicity in head and neck cancer (HNC) radiotherapy (RT). A few deep learning (DL) models have been proposed to predict the chance of xerostomia 12 months after RT with...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To compute effective doses associated with imaging of the extremities with a HiRise (CurveBeam AI, Hatfield, PA) cone-beam CBCT scanner specifically designed for weight-bearing imaging of the...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Claus Belka, Stefanie Corradini, George Dedes, Nikolaos Delopoulos, Christopher Kurz, Guillaume Landry, Ahmad Neishabouri, Domagoj Radonic, Adrian Thummerer, Niklas Wahl, Fan Xiao
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, LMU Munich, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), National Center for Radiation Oncology (NCRO), Heidelberg Institute for Radiation Oncology (HIRO)
Abstract Preview: Purpose: In MR-guided online adaptive radiotherapy, MRI lacks tissue attenuation information necessary for accurate dose calculations. Instead of using deep learning methods to generate synthetic CT i...
Authors: Anthony Hong Cheol Lim, Rayyan L Mahmood, Alexander Stanforth, Chris C. Wang, Mingyao Zhu
Affiliation: Georgia Institute of Technology, Emory University
Abstract Preview: Purpose: The purpose of this project is to test the feasibility of proton minibeam lattice radiotherapy within an existing clinical setting.
Methods:
The TOPAS code is used to model a scenario i...
Authors: Chen-Ju Feng, Shih-Ming Hsu, Chin-Hsiung Lin, Shih-Yong Luo, Shao-Chun Tseng, Chin-Hui Wu, Ya-Ru Yang
Affiliation: National Yang Ming Chiao Tung University, Koo Foundation Sun Yat-Sen Cancer Center, Tzu-Chi University, NanoRay Biotech Co., Ltd
Abstract Preview: Purpose: The range of auger electrons in water is 2~500 nm, and its linear energy transfer reaches 26 keV/ÎŒm. This study investigated the feasibility of the auger electron radiation therapy.
Method...
Authors: Grace Hutchinson, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: To assess the feasibility and consistency of the Sun Nuclear Corporation (SNC) MR conditional Quad Wedge, as an accessory to the IC Profiler-MR, and to evaluate beam output and energy in the ...
Authors: Melissa Bronson, Elizabeth L. Covington, Robert T. Dess, Joseph R. Evans, William C. Jackson, Charles S. Mayo, Michelle L. Mierzwa, Benjamin S. Rosen, VG Vinod Vydiswaran, Grant Weyburne, Zheng Zhang, Henry Zocher
Affiliation: PCORnetÂź, The National Patient-Centered Clinical Research Network, University of Michigan
Abstract Preview: Purpose: Diagnosis and staging are an integral part of cancer care, but this information is often scattered across various electronic medical records. The fragmentation increases overall documentation...
Authors: Christine V. Chung, Laurence Edward Court, Meena S. Khan, Ethan B. Ludmir, Rachael M. Martin Paulpeter, Saurabh Shashikumar Nair, Callistus M. Nguyen, Joshua S. Niedzielski, Luis Augusto Perles
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Spatially Fractionated Radiation Therapy (SFRT) has re-emerged as an efficacious treatment approach for bulky solid tumors. RapidArc Dynamic (RAD) has unique beam delivery capabilities that m...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Xinyuan Chen, Geoffrey D. Hugo, Alex T. Price, Pamela Samson, Tianyu Zhao
Affiliation: University Hospitals Seidman Cancer Center, University of South Florida, Washington University School of Medicine, WashU Medicine
Abstract Preview: Purpose: This study evaluates the financial viability of on-table simulation (CBCTp) enabled Halcyon system in radiation therapy. By leveraging Time-Driven Activity-Based Costing (TDABC), the analysis...
Authors: Robert Berry, John Buatti, Nathan Burger, Ryan T. Flynn, Greg Johns, Maksim Kravchenko, Sergey Kutsaev, Yen-Po Lee, Marcos Ruelas, Joel J. St-Aubin, Timothy J. Waldron
Affiliation: RadiaBeam Technologies, University of Iowa
Abstract Preview: Purpose: To report the factory acceptance tests of a preclinical linear accelerator, the FLEX-9 electron FLASH linac from RadiaBeam Technologies.
Methods: The FLEX-9 FLASH electron linac is designe...
Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers SĂžrensen, Matthias WĂŒrl
Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam
Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.
Methods:...
Authors: Barry Andricks, Stratton Black, Scott R. Floyd, Ashutosh Kotwal, Eric L. Martin, Stepan Mikhailov, Mark Oldham, Niccolo Terrando, Andrew Thompson, Ying Wu
Affiliation: Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University, Department of Radiation Oncology, Duke University Medical Center, Triangle Universities Nuclear Laboratory
Abstract Preview: Purpose: To evaluate and quantify the effects of high energy electron radiation delivered at FLASH and conventional dose rates on the reproductive capability of adult C. elegans nematodes.
Methods:...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study introduces a novel template-guided deep learning framework for primary gross tumor volume (GTVp) segmentation, addressing challenges posed by diverse tumor types and enabling a uni...
Authors: Xianjin Dai, PhD, Michael Gensheimer, Praveenbalaji Rajendran, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School
Abstract Preview: Purpose: Recent advances in the automatic delineation of radiotherapy treatment targets, which incorporate linguistic clinical data extracted by large language models (LLMs) into traditional visual-on...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of WisconsinâMadison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison
Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...
Authors: Claire Keun Sun Park, Atchar Sudhyadhom, Veena Venkatachalam, Noah Warner
Affiliation: HarvardâMIT Program in Health Sciences and Technology, Massachusetts Institute of Technology, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Modern radiotherapy achieves sub-millimeter spatial accuracy but fails to account for patient- and spatially-specific variations in biological response. Free radical generation (FRG), particu...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin
Affiliation: Labaid Cancer Hospital & Superspeciality Centre
Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...
Authors: Veng Jean Heng, Jan P. Seuntjens, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, Stanford University, Princess Margaret Cancer Centre & University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: We have developed a GPU-accelerated Monte Carlo (MC) simulation to determine the cumulative dose distribution of patients undergoing Total Skin Electron Therapy (TSET) using the Stanford tech...
Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu
Affiliation: Massachusetts General Hospital, MGH
Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...
Authors: Ming Chao, Karyn A Goodman, Yang Lei, Tian Liu, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for motion management in MRI-guided radiotherapy (MRIgRT), yet acquiring high-quality 3D images remains challenging due to time constraints and motion ar...
Authors: Pouya Azarbar, Nima Kasraie, Peyman Sheikhzadeh
Affiliation: UT Southwestern Medical Center, Shahid Beheshti University of Medical science, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose: Positron Emission Tomography (PET) is crucial for diagnosing and monitoring diseases due to its functional imaging capabilities. However, its high cost, significant radiation exposure, and li...
Authors: Seth Amofa, Erli Chen, Samuel A. Einstein, Ekinadoese Imudia Frias, Nupur Karmaker, Yinus Kawthara, Dulguun Myagmarsuren, Travis C. Salzillo, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Federal University Oye-Ekiti, Cheshire Medical Center, Dartmouth College, Penn State College of Medicine, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Virginia Tech Carilion School of Medicine
Abstract Preview: Purpose: Recent developments in the medical physics job market have made it increasingly difficult for radiotherapy centers, particularly in rural areas, to recruit qualified therapeutic medical physi...
Authors: Oluyemi Bright Aboyewa, KyungPyo Hong, Daniel Kim
Affiliation: Department of Radiology, Northwestern University
Abstract Preview: Purpose: While non-Cartesian MRI is desirable for fast imaging with high spatial resolution and robustness to motion, it requires long post-processing times. Preconditioning with an adequate density c...
Authors: Ashley Cetnar, Emily Y. Hirata, Cassandra Stambaugh
Affiliation: University of California San Francisco, Tufts Medical Center, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: To provide results from the first four years of the Medical Physics Leadership Academy (MPLA) Fundamental of Leadership Cohort program
Methods: The MPLA Cohorts program began with the Fund...
Authors: Davide Brivio, Lia Carroll, Juliane Daartz, Jan PO Schuemann, Piotr Zygmanski
Affiliation: Massachusetts General Hospital, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: We employ High-Energy Current (HEC) detectors for real-time monitoring of proton beams at conventional to FLASH dose rates. This would help overcome the need for fast and accurate dosimeters ...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: Rex A. Cardan, Carlos E. Cardenas, John B Fiveash, Joel A. Pogue, Richard A. Popple, Farnaz Rahim Li, Rodney J. Sullivan, Natalie N. Viscariello, Christopher Willey
Affiliation: The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: vBrain radiosurgery toxicity-rate is estimated via clinically-relevant isodose volume (IDV) thresholds according to HyTEC (e.g., V12Gyâ€10cc). HyperArcTM (HA) automated planning allows accurat...
Authors: Beverly Allen, Jay C. Buckey, David J. Gladstone, P. Jack Hoopes, David I Hunter, Armin Tavakkoli
Affiliation: Thayer School of Engineering, Dartmouth College, Geisel School of Medicine, Dartmouth College, Geisel School of Medicine, Thayer School of Engineering
Abstract Preview: Purpose: Hyperbaric oxygen (HBO) therapy immediately prior to radiation therapy has been proposed as treatment to enhance radiosensitivity of hypoxic tumors. A murine glioblastoma model was utilized t...
Authors: Wesley E. Bolch, Chansoo Choi, Chan Hyeong Kim, Suhyeon Kim, Bangho Shin, Yeon Soo Yeom
Affiliation: Hanyang University, University of Florida, 2) Department of Radiation Convergence Engineering, Yonsei University
Abstract Preview: Purpose: Task Group 103 of International Commission on Radiological Protection (ICRP) recently released new-generation adult and pediatric mesh-type reference computational phantoms (MRCPs) via ICRP P...
Authors: William E Burrell, Philip F. Durham, Anne N Hubbard, Yohan Akeakamai Walter, Hsinshun Terry Wu
Affiliation: Willis Knighton Cancer Center
Abstract Preview: Purpose: Linear accelerator (LINAC)-based single-isocenter, multi-target (SIMT) treatment has streamlined the stereotactic radiosurgery (SRS) workflow. However, off-isocenter treatment carries multipl...
Authors: Xun Jia, Heng Li, Wen Li, Devin Miles, Daniel Sforza, Lingshu Yin, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: FLASH therapy holds great potential to revolutionize radiotherapy by minimizing toxicities of normal tissues. The extraordinarily high dose rate of FLASH proton beam makes precise delivery to...
Authors: Ning Cao, Sunan Cui, Danielle P. Johnson Erickson, Juergen Meyer, Ramesh Rengan, Ben A Shaver, Jing Zeng
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: To investigate the immune response in primary irradiated tumors and non-irradiated tumors in a mouse melanoma xenograft model, comparing 18Gy of conventional (CONV) and ultra-high dose rate (...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...
Authors: William P. Donahue, Lauren Smith, Shu (Stella) Xing
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To quantify the dosimetric uncertainty of end-exhale gating as a function of breathing pattern.
Methods: A Truebeam delivered AP square fields to EBT4 film placed in the Quasar MRI4D M...
Authors: Samuel L. Brady, Joseph G. Meier
Affiliation: Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To establish noise reference levels for our pediatric hospital.
Methods:
Water equivalent diameter (Dw) and image noise was automatically measured by using a global noise algorithm i...
Authors: Rohith Kaiyum, Ozzy Mermut, Alexandra Rink
Affiliation: Department of Medical Biophysics, University of Toronto, Department of Physics and Astronomy, York University
Abstract Preview: Purpose: To investigate the relationship between chemical features and real-time response to ionizing radiation dose of radiochromic diacetylene crystals.
Methods: A number of radiochromic diacetyl...
Authors: David Chighvinadze, Indra J. Das, Jeremy D. Donaghue, Kevin Stephans, Gregory Videtic, Sugandima Weragoda, Ping Xia
Affiliation: Cleveland Clinic, Cleveland Clinic Sandusky, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Cleveland Clinic Fairview
Abstract Preview: Purpose:: Evaluate the impact of lung density variations on plan quality and delivery parameters in lung SBRT Plans.
Methods: For a hypothetical case with a real patient anatomy, three GTVs with vo...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Amrit Kaphle
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To assess the effectiveness of various nanoscale models of gold nanoparticle (GNP)-laden cells for Monte Carlo (MC) studies of GNP-mediated radiation dose enhancement/DNA damage.
Metho...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: In radiation therapy, patient setup errors have been a primary concern impacting dose delivery accuracy. A robust treatment plan is essential to mitigate these errors. This study aimed to eva...
Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou
Affiliation: University of Kentucky, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...
Authors: Hajee Reyaz Ali Sahib, Sangeeta Hazarika, Muthukumaran Manavalan, Jaswin Raj, Daya Nand Sharma, Seema Sharma, Subramani Vellaiyan
Affiliation: AIIMS NCI Jhajjar, PTW North America Corporation, All India Institute of Medical Sciences
Abstract Preview: Purpose:
Purpose is to investigate the effect of extended source-to-imager distances (SID) on the resolution of VMAT patient-specific quality assurance (PSQA) in portal dosimetry (PD).
Methods:<...
Authors: Xiangli Cui, Wei Han, Jie Li, Lingling Liu
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences
Abstract Preview: Purpose: To investigate the influence of tissue heterogeneity on proton beam linear energy transfer (LET) and relative biological effectiveness (RBE) using nine RBE models. This study quantifies the i...
Authors: Anthony J. Doemer, Aharon Feldman, Ian Gallagher, Yimei Huang, Brett M. Miller, Benjamin Movsas, Kundan S Thind
Affiliation: Henry Ford Health
Abstract Preview: Purpose: CT-guided adaptive radiation therapy (CTgART) is a technical, resource intensive, procedure that involves many different radiation oncology team members. To ensure consistent, high-quality CT...
Authors: Samuel L. Brady, Kevin Chen, Joseph G. Meier
Affiliation: University of Cincinnati, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose: Conebeam-CT (CBCT) acquisition protocols typically do not distinguish between adults and pediatrics. In collaboration with a fluoroscopically-guided interventional (FGI) manufacturer, new, do...
Authors: Benjamin J. Sintay, Caroline Vanderstraeten, David B. Wiant
Affiliation: Fuse Oncology, Cone Health
Abstract Preview: Purpose: The Joint Commission (JC) mandates that healthcare organizations establish and evaluate staff competencies to ensure safe and effective patient care. In the context of increasing sub-speciali...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock
Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research
Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...
Authors: Krishnendu Saha
Affiliation: Cleveland Clinic Foundation
Abstract Preview: Purpose: The goal is to improve quantitative accuracy of a Maximum-a-posteriori expectation maximization (MAPEM) reconstruction of SPECT phantom images by optimizing Gibbs prior parameters.
Methods...
Authors: Omar Awad, Alfredo Enrique Echeverria, Issam M. El Naqa, Daniel Allan Hamstra, Yiding Han, Ryan Lafratta, Abdallah Sherif Radwan Mohamed, Piyush Pathak, Zaid Ali Siddiqui, Baozhou Sun, Vincent Ugarte
Affiliation: H. Lee Moffitt Cancer Center, Harris Health, Baylor College of Medicine
Abstract Preview: Purpose:
Accurate detection and segmentation of brain metastases are critical for diagnosis, treatment planning, and follow-up imaging but are challenging due to labor-intensive manual assessments ...
Authors: Davide Brivio, Erno Sajo, Ryan Williams, Piotr Zygmanski
Affiliation: University of Massachusetts Lowell, Brigham and Women's Hospital, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a non-invasive 3D in-vivo dosimetry tool exploring the relationship between positron annihilations and dose per voxel using Monte Carlo simulation. The Positron Guided Radiation Th...
Authors: Scott James Bright, Hadil Elldakli, Mojtaba Hoseini-Ghahfarokhi, Rishab Kolachina, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Gabriel O. Sawakuchi, Walison Augusto Silva Brito, Mark Wasley
Affiliation: MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center, Medical College of Georgia
Abstract Preview: Purpose:
Glutaminase 1 (GLS1) is an intracellular enzyme crucial for generating antioxidants such as glutathione (GSH). GSH neutralizes reactive oxygen species (ROS) induced by radiotherapy. About ...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-”m tungsten wire was imaged at ...
Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...
Authors: Mohammadreza Ay, Nahal Daneshgar, Nima Kasraie, Abbas Monsef, Zeinab Peymani, Hadi Rezaei, Peyman Sheikhzadeh
Affiliation: University of Minnesota Medical School, Radiation Oncology, Department of Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Shiraz University of Medical Sciences, Department of Medical Physics, Tehran University of Medical Sciences, Department of Medical Physics and Biomedical Engineering, UT Southwestern Medical Center, Imam Khomeini Hospital Complex,Tehran University of Medical Sciences
Abstract Preview: Purpose:
This study aims to design and simulate an innovative pediatric-dedicated SPECT scanner optimized for childrenâs unique anatomical and safety needs by enhancing sensitivity in data acquisit...
Authors: Ali Ajdari, Thomas R. Bortfeld, Christopher Bridge, Gregory Buti, Marcela Giovenco, Fredrik Lofman, Gregory C. Sharp, Helen A Shih, Tugba Yilmaz
Affiliation: Massachusetts General Hospital, RaySearch Laboratories, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Defining radiation target volumes with accurate integration of the neuroanatomy is one of the major difficulties in designing glioma treatments. We developed a deep learning network for norma...
Authors: George Agrotis, Marios Myronakis, Dimitrios Samaras, Kyriaki Theodorou, Ioannis Tsougos, Vassilios Tzortzis, Maria Vakalopoulou, Alexandros Vamvakas, Aikaterini Vassiou, Marianna Vlychou
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Radiology, University of Thessaly, Netherland Cancer Institute, Department of Urology, University of Thessaly, CentraleSupelec, University Paris-Saclay
Abstract Preview: Purpose: Prostate cancer (PCa) diagnosis remains challenging due to discrepancies in Gleason Scoring (GS) and risks of overdiagnosis and underdiagnosis. Multiparametric MRI (mpMRI), including Apparent...
Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Jiajian Shen
Affiliation: Department of Radiation Oncology, Mayo Clinic, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study aims to develop the first SPArc optimization algorithm based on the Dynamic Programming (SPArc-DP), to improve the treatment delivery efficiency for synchrotron-accelerator-based P...
Authors: Shiho Amster, Ryan Andosca, Igor Barjaktarevic, Michael Vincent Lauria, Daniel A. Low, Dylan P. O'Connell, Ann Raldow, Brad Stiehl
Affiliation: Department of Pulmonology, University of California Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Image-based biomarkers could be useful for disease diagnosis and prognosis, especially in heterogeneous lung diseases like COPD. The purpose of this study is to assess the feasibility of usin...
Authors: Catherine Coolens, Janny Yeyoung Kim, Michael Milosevic, Noha Sinno
Affiliation: Princess Margaret Hospital, University of Toronto
Abstract Preview: Purpose: In solid tumors, Interstitial fluid pressure (IFP) acts as a barrier to molecular transport to the tumor center and serves as a predictor of cancer patientsâ treatment responsiveness. The nov...
Authors: Peter Jermain, Ying Niu, Abdul Rashid, Yuan Yuan, Mohammad Zarenia
Affiliation: Medstar Georgetown University Hospital, MedStar Georgetown University Hospital, Department of Radiation Medicine, MedStar Georgetown University Hospital
Abstract Preview: Purpose: ZAP-X is a self-shielded radiosurgery system that utilizes a linac-based isocentric technique and a compact gyroscopic gantry design. While it provides a large solid angle for beam orientatio...
Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong
Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University
Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: Yuqi Yang, Fang-Fang Yin
Affiliation: Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Reactive oxygen species (ROS) are unstable molecules which play important roles in the cellular process after Flash radiotherapy. The rapid changes in ROS levels during treatment may provide ...
Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...
Authors: Harald Keller, Iymad Mansour, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...
Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health
Abstract Preview: Purpose: This study involved the use of Accurayâs TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accurayâs Radixact machine, and dose calculation algorithm, do...
Authors: Konstantinos Chatzipapas, George C. Kagadis, Panagiotis Konstas, Dimitris N. Mihailidis, Dimitris Visvikis
Affiliation: LaTIM, INSERM UMR1101, University of Pennsylvania, LaTIM, INSERM, University of Brest, University of Patras
Abstract Preview: Purpose: This study investigates the temporal evolution of radiolytic species (H3O+, OHâą, OH-) in water under electron and proton irradiation using the mesoscopic chemistry model that allows longer te...
Authors: Meghan Lubner, Aria M. Salyapongse, Teva Shapiro, Scott D. Slavic, Timothy P. Szczykutowicz, Giuseppe Toia, Zhye Yin
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose:
To compare iodine quantification on a prototype deep silicon photon-counting detector (PCD) CT and conventional clinical energy-integrating (EID) dual-energy (DE) CT.
Methods:
A phan...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...
Authors: Xiangli Cui, Zilei Fu, Man Hu, Wanli Huo, Xiaoqing Wu, Jianguang Zhang, Yingying Zhang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
Using Stable Diffusion to generate images of the knee in different disease states can enrich the medical imaging database and inject new vitality into the field of medical imaging analysis...
Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...
Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh
Affiliation: Tufts Medical Center
Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...
Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...
Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...
Authors: Smith Apisarnthanarax, Clemens Grassberger, John Kang, Yejin Kim, Justin Leu, Dominic A. Maes, Matthew J. Nyflot, Ramesh Rengan, Annemarie Shepherd, Jing Zeng
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: Reirradiation (ReRT) is a rapidly growing clinical challenge driven by better systemic therapy and longer survival, though clear guidelines for ReRT are lacking. Fitting traditional normal ti...
Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang
Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute
Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...
Authors: Ben Piacitelli, Celeste Winters
Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University
Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...
Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez
Affiliation: University of Houston, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To improve lung dosimetry for 90Y-radioembolization planning, CT-based techniques have been proposed for patient-specific lung mass estimation instead of assuming nominal 1 kg lung masses. He...
Authors: Ryan Gentzler, Xin He, James Larner, J.T. Morgan, Cam Nguyen, Wendy Stewart, Krishni Wijesooriya, Grant Williams
Affiliation: Department of Physics, University of Virginia, Department of Radiation Oncology, University of Virginia, Division of Hematology & Oncology, Department of Medicine, University of Virginia
Abstract Preview: Purpose: Some recent studies have shown Overall Survival (OS) of advanced-stage lung cancer patients treated with chemo-radiation therapy (CRT) is correlated with heart dose [1-5], while in other stud...
Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying
Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital
Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...
Authors: Jeffrey Andrews, Nathan E. Becker, Juanita Crook, Andrew Jirasek, Matthew Jonathan Muscat
Affiliation: UBC, BC Cancer Agency, BC Cancer
Abstract Preview: Purpose: To map dosimetry and imaging information to ultrasound and multi-parametric magnetic resonance (mpMR) guided trans-perineal core-needle biopsies, performed during two-fraction prostate high-d...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patientsâ setups. MAHR complements current image-guidance...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere
Affiliation: University of Chicago
Abstract Preview: Purpose: We assess two multi-measurement acquisition schemes for material decomposition with x-ray phase-contrast imaging (XPCI); demonstrating for the first time that multi-distance imaging can match...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Wamied T. Abdel-Rahman, Iqbal AlAmri, Lma Alahmare, Ghada Aldosary, Marwa Alghamdi, Lujain Aljadou, Yarah Alkhulaif, Abdullah A. Alshreef, Ohoud Alsubaie, Hoton Alsufyani
Affiliation: Loma Linda University Medical Center, Princess Nourah Bint Abdulrahman University, King Fahad Specialist Hospital, KAMC- Ministry of National Guard Health Affairs, SQCCCRC, KASCH- Ministry of National Guard Health Affairs
Abstract Preview: Purpose: The shortage of qualified medical physicists in many developing countries is due to multiple factors such as lack of awareness or access to graduate and residency training programs. An outrea...
Authors: Ziqi Gao, Lei Xing, Siqi Ye, S. Kevin Zhou
Affiliation: Department of Radiation Oncology, Stanford University, University of Science and Technology of China (USTC)
Abstract Preview: Purpose: To address the challenge of high memory usage in volumetric cone-beam CT (CBCT) imaging, we propose a method that combines joint reconstruction and super-resolution for sparsely sampled CBCT ...
Authors: Junwen Liu, Mengzhen Wang, Ning Wen, Jifeng Xiao, Fuhua Yan, Yanzhao Yang, Xuekun Zhang, Zheyu Zhang
Affiliation: Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University, The SJTU-Ruijin-UIH Institute for Medical Imaging Technology, Shanghai Jiaotong University Schoo of Medicine
Abstract Preview: Purpose:This study aims to develop and evaluate a large language model (LLM) fine-tuned to generate consistent and accurate impressions from imaging findings. Additionally, the study investigates the ...
Authors: Catherine Coolens, Robert K. Heaton, Lalageh Mirzakhanian, Tasnim Rahman, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, McGill University, Princess Margaret Cancer Centre, Princess Margaret Hospital, University of Toronto
Abstract Preview: Purpose: Commissioning of a Gamma KnifeÂź (GK) (Elekta, Sweden) unit requires precise dosimetric reference measurements, particularly for small fields. The IAEA TRS-483/AAPM TG-155 code of practice (20...
Authors: Sang Hyun Cho, Sandun Y. Jayarathna, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To develop/validate a Monte Carlo (MC) model of an experimental benchtop x-ray fluorescence computed tomography (XFCT) system with a pixelated CdTe detector that can be used for MC simulation...
Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb
Affiliation: GenesisCare
Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Smith Apisarnthanarax, Stephen R. Bowen, Sunan Cui, Jie Fu, Clemens Grassberger, Yulun He, Yejin Kim, Matthew J. Nyflot, Sharon Pai
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: 99mTc-sulfur colloid SPECT imaging enables quantitative assessment of voxel-wise liver function in patients with hepatocellular carcinoma (HCC). Accurately predicting post-radiotherapy (RT) l...
Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...
Authors: Hassan Bagher-Ebadian, Ahmed I Ghanem, Joshua P. Kim, Chengyin Li, Rafi Ibn Sultan, Kundan S Thind, Dongxiao Zhu
Affiliation: Wayne State University, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Accurate segmentation of the Left Anterior Descending (LAD) artery in free-breathing 3D treatment planning CT is crucial for radiotherapy but remains challenging due to its small size, comple...
Authors: Nicholas Joseph Casteloes, Brian T Collins, Sean P Collins, Shiva K. Das, Panayiotis Mavroidis, Michael Repka, Simeng Suy
Affiliation: University of South Florida, University of North Carolina
Abstract Preview: Purpose: To correlate four rectal symptoms with the dose to rectum in patients, who received SBRT with Cyberknife for prostate cancer. Also, to fit those dosimetric and outcome data by using a normal ...
Authors: Gregory A Azzam, Danielle Cerbon, Laura Huang, Panayiotis Mavroidis, Diana Molinares, Stuart E Samuels, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center, University of Miami Sylvester Comprehensive Cancer Center, Mount Vernan Rehabilitation Medicine Associates, Department of Radiation Oncology, University of Miami, University of North Carolina
Abstract Preview: Purpose: This study aims at performing a normal tissue complication probability (NTCP) modeling by fitting the doses to the skin, sternocleidomastoid (SCM) muscle and subcutaneous tissue (subcut) stru...
Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson
Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital
Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...
Authors: Ahmet S. Ayan, Estelle Batin, Austin M. Faught, Peter E. Klages, Eunsin Lee, Collin Nappi, Mina Okello, Meghana Ramani, Zachary X. Richards, Parisa Sadeghi
Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University
Abstract Preview: Purpose: Neutron doses are not modelled in proton treatment planning systems, so measurements were taken with two independent dosimeter types to quantify representative neutron fetal doses in pencil b...
Authors: Md Mainul Abrar, Yujie Chi
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Peymon Ghazi
Affiliation: MALCOVA Inc.
Abstract Preview: Purpose: To develop a near scatterâfree breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...
Authors: Palanisamy Karunanithi, Karthikeyan Perumal, Siva Subramanian Vadivel
Affiliation: Dr. Kamakshi Memorial Hospital
Abstract Preview: Purpose:
Recent advancements in high dose-rate (HDR) brachytherapy include the image guidance, new applicators, and dose calculation algorithms. Brachytherapy has steep dose gradient, hence relativ...
Authors: Jason Ellsworth, Mark Mishra, Jason K Molitoris, Lei Ren, Dario B. Rodrigues, Paul Turner, Graeme Woodworth
Affiliation: University of Maryland School of Medicine, Department of Neurosurgery, University of Maryland School of Medicine, University of Maryland, Department of Radiation Oncology, University of Maryland School of Medicine, Pyrexar Medical
Abstract Preview: Purpose: Hyperthermia therapy (HT) involves increasing tumor temperatures to 40-44°C and is a potent radio- and chemosensitizer for treating solid tumors. Current clinical strategies to heat deep-seat...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: The Sun Nuclear MapCheck3 device is used for patient-specific QA. While it is typically employed in perpendicular field-by-field delivery using the Isocentric Mounting Fixture, fields not ful...
Authors: Kevin M Brom, Josep Chorro Bas, RosaAnna Chorro Bas, Andres Climent Rubio, Jaydev K. Dave, Tobias Kummer, Larissa Shiue, Donald J Tradup
Affiliation: Mayo Clinic, Prehospital Critical Care Training Group
Abstract Preview: Purpose: To design and evaluate the functionality of a vascular flow phantom for contrast-enhanced ultrasound imaging (CEUS).
Methods: A microcontroller-generated signal was amplified by a cust...
Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Darren M. C. Poon, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study investigates optimal treatment strategies utilizing MR-linac for extremity lesions, with a specific focus on a 0.6 cm deep lesion in the right palm. The magnetic field-induced dose...
Authors: Simona Cacciatore, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Julien Smeets, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To evaluate time reduction strategies for the Dynamic Collimation System (DCS) using an IBA (Louvain-la-Neuve, Belgium) proton therapy system. Delivery time for a multi-energy-layer patient s...
Authors: Panagiotis Iliopoulos, Marios Myronakis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly
Abstract Preview: Purpose: To estimate individualized absorbed dose at Organs at Risk (OARs) from kV Cone Beam CT (CBCT) imaging in the pelvic area, prior radiotherapy, and assess excess risk for secondary malignancies...
Authors: Wesley E. Bolch, Chansoo Choi, Robert Joseph Dawson, Michael Lassmann, Maikol Salas-Ramirez, Bangho Shin, Johannes Tran-Gia, Yitian Wang
Affiliation: Department of Nuclear Medicine, University Hospital WĂŒrzburg, University of Florida
Abstract Preview: Purpose: Conduct a parameterized library of mesh-type skeletal models across the lumbar vertebrae. In radiopharmaceutical dosimetry, the hematopoietic active bone marrow is typically a dose-limiting n...
Authors: Yao Chen, Lesley A Jarvis, Allison Matous, Rongxiao Zhang
Affiliation: Dartmouth College, University of Missouri, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: Precise patient positioning is critical in accelerated partial breast irradiation (aPBI) to ensure accurate dose delivery to the tumor bed while minimizing exposure to surrounding healthy tis...
Authors: Blessing Akinro, Soumyanil Banerjee, Ming Dong, Carri K. Glide-Hurst, Prashant Nagpal, Chase Ruff, Nicholas R. Summerfield, Timothy P. Szczykutowicz
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Departments of Radiology and Medical Physics, University Wisconsin-Madison, Department of Radiology, University of Wisconsin-Madison, Department of Computer Science, Wayne State University, Department of Human Oncology
Abstract Preview: Purpose: Radiation dose to coronary arteries (CAs) during thoracic radiotherapy (RT) is linked to cardiotoxicity. However, precise CA delineation for avoidance is limited by image quality and CA compl...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center
Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...
Authors: Stephanie Bennett, Ross I. Berbeco, Ning Jin, Sonal Josan, Justin Michael Sheetz, Atchar Sudhyadhom
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Massachusetts - Lowell, Siemens Healthineers, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women's Hospital
Abstract Preview: Purpose: AGuIX, a Gadolinium-based theranostic radiosensitizing nanoparticle, is currently under clinical evaluation in Europe and the US. Using patients from the double-blinded NanoBrainMets trial, u...
Authors: Wesley E. Bolch, Emily L. Marshall, Dhanashree Rajderkar, Wyatt Smither
Affiliation: University of Florida
Abstract Preview: Purpose: To determine the accuracy of TotalSegmentator, an AI-based automatic segmentation toolkit, on pediatric CT scans as the original software was trained on adult image datasets with a mean patie...
Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou
Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Frank F. Dong, Megan C. Jacobsen, Ke Li, Xinming Liu, John Rong
Affiliation: UT MD Anderson Cancer Center
Abstract Preview: Purpose: We aimed to understand the physical performance of a CdTe PCD-based detector system within a whole-body PCD-CT scanner, with the goal of optimizing its clinical application. Instead of relyin...
Authors: Mohammed Alzaabi, Abderaouf Behouch, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: Spectral Photon Counting CT (SPCCT) has emerged as a transformative technology in CT imaging capable of producing images from distinct energy windows, allowing improved material characterizat...
Authors: Chao Guo, Xinhua Li, Michael F. McNitt-Gray, Di Zhang, Yifang (Jimmy) Zhou
Affiliation: UCLA, David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The objective was to quantify the liver fat volume fraction (FVF) with virtual monochromatic imaging (VMI) using photon-counting CT (PCCT) and dual energy CT (DECT).
Methods: A custom desi...
Authors: Carina Gassner, Guyue Hu, Thomas Kröncke, Christopher Kurz, Guillaume Landry, Katharina Niepel, Katia Parodi, Franka Risch, Florian Schwarz
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Diagnostic and Interventional Radiology, University Hospital Augsburg, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich)
Abstract Preview: Purpose: To evaluate the performance of a clinical photon-counting CT (PCCT) scanner in terms of proton relative stopping power (RSP) estimation using PCCT data and to compare the impact of different ...
Authors: Ricardo Garcia Santiago, Narges Miri, Daryl P. Nazareth, Ankit Pant, Mukund Seshadri
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To develop a transformer-based deep learning network framework for predicting VMAT dose distributions. This can provide fast and efficient calculations with accuracies potentially comparable ...
Authors: Hyunuk Jung, Fiona Li, Brian Marples, Michael Milano, Sean M. Tanny, Dandan Zheng, Yuwei Zhou
Affiliation: Department of Radiation Oncology, University of Rochester, University of Rochester Medical Center, University of Rochester
Abstract Preview: Purpose:
Recurrent GBM remains one of the most challenging cancers, with limited treatment options. We investigated potential planning parameters of SFRT, a novel radiotherapy technique that delive...
Authors: Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke
Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health
Abstract Preview: Purpose: Precisely identifying orientation of implanted seeds on post-implant CTs is challenging. This research addresses the dosimetric uncertainties stemming from uncertainties in identifying seed o...
Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Paige A. Taylor
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To develop a machine learning model for predicting dose delivery accuracy and identifying its key factors in IROCâs proton phantom program.
Methods: IROCâs proton QA program has six proton...
Authors: David Alcorta, Joseph Farina, Timothy Haystead, Philip Hughes, Keshav Jha, Mark Oldham, Victoria J. P. Radosova
Affiliation: Duke University Department of Pharmacology and Cancer Biology, Medical Physics Graduate Program, Duke University, Duke University Department of Medicine, Duke University, Duke University Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: This study attempts to simulate the activation of targeted photodynamic molecules using visible laser light and characterize the direct Reactive Oxygen Species (ROS) generated by Cherenkov an...
Authors: Eric Aliotta, Michalis Aristophanous, Joseph O. Deasy, Bill Diplas, Milan Grkovski, James Han, Vaios Hatzoglou, Jeho Jeong, Nancy Y Lee, Ramesh Paudyal, Nadeem Riaz, Heiko Schoder, Amita Shukla-Dave
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To forecast radiotherapy treatment response for head and neck cancer (HNC) using multimodality imaging and personalized radiobiological modeling.
Methods: Multi-modality imaging data from ...
Authors: Abdullah Hidayat, Wazir Muhammad
Affiliation: Florida Atlantic University
Abstract Preview: Purpose: This study aims to predict Head and Neck cancer using an artificial neural network (ANN) through readily available basic health data. The goal is to uncover hidden patterns and predictors in ...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (â„6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...
Authors: Jeremy T. Booth, Sonja Dieterich, Jonathan Hindmarsh, Paul J. Keall
Affiliation: Northern Sydney Cancer Centre, Royal North Shore Hospital, UC Davis Medical Center, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose: Prospective hazard analysis (PHA) is a core medical physics function. PHA was investigated by AAPM Task Group 100 for the purpose of keeping patients safe and assessing the risks of novel tec...
Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang
Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University
Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...
Authors: Mireille Conrad, CĂ©dric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon
Affiliation: Clinique De Genolier
Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...
Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng
Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...
Authors: Yussuf A. Abdelal, Junguo Bian, Michael Delafuente, Sebastien A. Gros, Hyejoo Kang, Luke Layman, M Mahesh, John C. Roeske
Affiliation: Department of Radiology and Medical Imaging, Stritch School of Medicine, Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Johns Hopkins Univ
Abstract Preview: Purpose: This study evaluates the feasibility of optimizing 4DCBCT imaging protocols for gated lung SBRT, by reducing dose while maintaining the image quality required for accurate patient alignment.<...
Authors: Hyejoo Kang, Andrew Keeler, Mathias Lehmann, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Varian Imaging Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose: Markerless tumor tracking (MTT) using dual-energy (DE) subtraction imaging is being considered as a non-invasive method to track tumors during lung cancer treatment. Prior to clinical impleme...
Authors: Douglas John Moseley, David M. Routman, Satomi Shiraishi, Donald C Smith, Mark R. Waddle
Affiliation: University of Denver, Mayo Clinic
Abstract Preview: Purpose: About 6% of patients treated for the first time in our department have received radiotherapy previously at an outside institution. We aim to provide an automatic quality assurance of identify...
Authors: Teh Lin, Anna Oneil
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...
Authors: Ali Ammar, Quan Chen, Jingwei Duan, Yi Rong, Nathan Y. Yu, Libing Zhu
Affiliation: Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Clinical performance of deep learning-based auto-segmentation (DLAS) can degrade over time due to AI âagingâ from unseen data input compared to the initial model training data. This study aim...
Authors: Haiqa Arain, Ping Xia, Zhexuan Zhang
Affiliation: Cleveland Clinic
Abstract Preview: Purpose: To quantify water contents and thickness of wet towel (as a flexible bolus) on curved surface dose for partial breast irradiation.
Methods: Two VMAT partial breast plans (3000 cGy in 5...
Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer
Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: To evaluate iodine quantification and CT number accuracy in coronary CT angiography (CTA) using standard and ultra-high resolution (UHR) modes of photon-counting CT (PCCT) across different do...
Authors: Rick Holly, Sumudu Katugampola
Affiliation: Gesinger Medical Center, Geisinger Medical Center
Abstract Preview: Purpose:
To quantitatively analyze long term variations in optical density of un-irradiated and irradiated EBT3 radio-chromic films and their effects on dose calibration curves in a clinical settin...
Authors: Zahra Alyani Nezhad, Carrie Bartels, Rachel Bladorn, Sean D. Rose, Kelsey Schluter, Timothy P. Szczykutowicz
Affiliation: Departments of Radiology and Medical Physics, University Wisconsin-Madison, University of Wisconsin Madison, University of Wisconsin-Madison, University of Texas at Houston Medical School, University of Wisonsin-Madison
Abstract Preview: Purpose: Pulmonary embolism is a life-threatening condition, and computed tomography pulmonary angiography (CTPA) is the gold standard for diagnosis. Inadequate contrast enhancement often leads to a h...
Authors: Casey C. Heirman, Kyle J. Lafata, Xiang Li, Breylon Riley, Jack B Stevens, Tammara Watts
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: To leverage quantitative fluorescence imaging and spatial transcriptomics for characterizing the spatial and molecular heterogeneity of the tumor microenvironment (TME) in HPV+ head and neck ...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Mohammad Nazmul Alim, Regina DeWitt
Affiliation: Department of Physics, East Carolina University,, Department of Physics, East Carolina University
Abstract Preview: Purpose: This study quantifies the ability of Luxel (AlâOâ:C) to measure radiation dose from a Moxtek X-ray source. Key aspects of OSL dosimetry, including OSL curves, dose response, depth dose, and b...
Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...
Authors: Ramesh Boggula, Yash Somnay, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC, Wayne State University
Abstract Preview: Purpose: Spatially fractionated radiation therapy (SFRT) allows delivery of therapeutic doses to bulky tumors otherwise limited by dose-volume effects that threaten organ-at-risk tolerances. For negle...
Authors: Go Akamatsu, Han Gyu Kang, Chie Seki, Hitomi Sudo, Hideaki Tashima, Chie Toramatsu, Hidekatsu Wakizaka, Iwao Yamaya, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose:
Tumor oxygen status, which provides important information to optimize particle therapy, may constantly change during a treatment period of several weeks. However, it is impractical to perf...
Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger
Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao
Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.
Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...
Authors: Matthew Case, Richard Castillo, Sunil Dutta, Edgar Gelover, Katja M. Langen, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory University
Abstract Preview: Purpose: To evaluate the application of LETd and track-end (TE) objective functions during the optimization of breast proton therapy plans to decrease the risk of lung toxicity and rib fractures.
M...
Authors: Vishruta A. Dumane, Andrew Lukban, Kiran Pant, Charlotte Elizabeth Read, Ren-Dih Sheu, Nadia M. Vassell
Affiliation: Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology
Abstract Preview: Purpose: This work introduces a refined in-house modified COMS eye plaque management system to streamline processes, reduce redundancies, and enhance usability.
Methods: A web-based application wit...
Authors: Lili Chen, Xiaoming Chen, Chang Ming Charlie Ma, Joshua Meyer
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Fast CBCT (HyperSight) acquisition technique together with a surface-guided breath-hold (SGBH) would allow a better image quality for accurate target/organ delineation. It facilitates breath-...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose: To analyze the actual doses received during radiotherapy for head and neck cancers (HNC) using Velocity, providing insights for adaptive radiotherapy decision-making.
Methods: Thirty-three...
Authors: Diandra Ayala-Peacock, Junzo Chino, Oana I. Craciunescu, Allison Jones, Kyle J. Lafata, Kim Light, Sheridan G. Meltsner, Jack B Stevens
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke University Medical Center
Abstract Preview: Purpose: This study aims to develop an MR-based method that retrospectively correlates longitudinal changes in morphology and physiology for the bulboclitoris and vaginal canal with dose received duri...
Authors: Brankica Andelic, Young-Bin Cho, Tara M. Gray, Bingqi Guo, Andrew Robert Hadfield, Hakan Nordstrom, Jacob Scott, John Suh, Nara Yoon
Affiliation: Adelphi University, Elekta, Cleveland Clinic
Abstract Preview: Purpose: To investigate the biological effect of Spatially Fractionated Radiation Therapy (SFRT) within Gamma-Knife (GK) using retrospective planning for brain metastases patients. This study presents...
Authors: Tirthraj Adhikari, Timothy J Allen, Abdullah A. Alshreef, Clara Ferreira
Affiliation: Medical School Department of Radiation Oncology University of Minnesota, University of Minnesota, Loma Linda University Medical Center
Abstract Preview: Purpose: GammaTile Brachytherapy with 131Cs is an effective treatment for glioblastomas, offering local control with minimal radiation necrosis. While the line source model is preferred for dose distr...
Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: The CQ Medical kVue Pronumbra Head & Neck (HN) System is a new immobilization device for proton therapy. The mask includes 4 large knobs that attach to the board with built-in shims. These kn...
Authors: Garrett Russell Hamilton, Joshua Misa, Damodar Pokhrel, William St. Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Recurrent brain metastasis is very common, and patients who previously received whole-brain radiotherapy (WBRT) may receive an additional course(s) of stereotactic radiosurgery (SRS) to selec...
Authors: Yukio Fujita, Satoshi Ishikura, Fumiki Ito, Yujiro Nakajima, Takumi Sakamoto, Naoki Tohyama, Ryohei Yamauchi
Affiliation: Komazawa University Graduate School, St. Luke's International Hospital
Abstract Preview: Purpose: The aperture shape controller (ASC) is an Eclipse feature that increases muti-leaf collimator (MLC) aperture size. This study aimed to evaluate the effects of ASC settings on the robustness o...
Authors: Carl D. Elliston, Lawrence Koutcher, Michael J. Price, Adam C. Riegel, Michael B Sisti, Tony J.C. Wang, Andy (Yuanguang) Xu
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: An inverse treatment planning software was recently introduced to Gamma Knife radiosurgery. The purpose of this study is to compare the plan quality of the Gamma Knife âLightningâ with that o...
Authors: Reza Farjam, Russell K Hales, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam angles and off-axis isocenter selection are important to achieve high quality plan and collision-free delivery in stereotactic body radiotherapy (SBRT) of the posteriorly located...
Authors: Elizabeth K. Butker, Cara Cimmino, Jenna L. Fair, David Matthew Giles, Bruce Hershatter, Shadab Momin, Sagar Patel, John Pattaras, Kamran Salari Salari, Aaron Weiss
Affiliation: Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: Prostate cancer patients may experience a local-only failure after radiation. While high-dose-rate (HDR) brachytherapy may have more favorable toxicity profile and cancer control compared to ...
Authors: Angela Gearhardt, Stephen F. Kry, Christopher Ryan Peeler, Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: A growing number of radiation therapy (RT) patients have cardiovascular implantable electronic devices (CIEDs). Patients with CIEDs must be carefully managed because the devices are susceptib...
Authors: Yong Chen, Gilberto Gonzalez, Omprakash Gottam, Liangzhong Xiang
Affiliation: University of California, Irvine, Koneru Lakshmaiah Education Foundation, University of Texas at San Antonio., University of Oklahoma Health Science Center
Abstract Preview: Purpose: Clinics currently lack techniques for real-time, in vivo monitoring of radiation therapy (RT), which is desirable for precise treatment. Radiation-induced acoustic computed tomography (RACT) ...
Authors: Rituparna Basak, Maede Boroji, Renee F Cattell, Vahid Danesh, Imin Kao, Kartik Mani, Xin Qian, Samuel Ryu, Tiezhi Zhang
Affiliation: Stony Brook Medicine, Stony Brook University, Washington University in St. Louis, Stony Brook University Hospital
Abstract Preview: Purpose: Fundamental qualitative characteristics physicians use to differentiate skin lesion subtypes include asymmetry, border irregularity, and color. Radiomic features have potential to quantify th...
Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...
Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu
Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Filament deposition modeling (FDM) 3D printers may utilize proprietary calibration methods inadequate for medical imaging. Proper techniques are necessary to achieve imaging uniformity standa...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Lori Buchholtz, Alison Garda, Chris L. Hallemeier, Kathryn L. Kolsky, Han Liu, Joseph John Lucido, Marisa Schinter, Andrew J. Veres, Sara Walerak
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The C_START initiative aims to streamline and simplify the Direct-to-Unit (DtU) clinical setup and treatment planning process for photon radiation therapy, particularly for emergent cases suc...
Authors: Eric C. Ford, Yulun He, Minsun Kim, Dustin Melancon, Juergen Meyer, Dong Joo Rhee, Yinghua Tao
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, MD Anderson Cancer Center, University of Washington
Abstract Preview: Purpose: To develop and evaluate an automated-planning technique capable of generating high-quality treatment plans for hippocampal-sparing-whole-brain radiation therapy.
Methods: An auto-planning ...
Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei
Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...
Authors: Serhii Brovchuk, Viktor M. Iakovenko, Nataliya Kovalchuk, Yuliia Lozko, Zoia Shepil, Natalka Suchowerska, Ruslan Zelinskyi
Affiliation: Kyiv Regional Oncology Dispensary, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, School of Physics, The University of Sydney, Medical Physics Department, Medical center of Yuriy Spizhenko, Department of Radiation Oncology, UT Southwestern Medical Center, Stanford Cancer Center
Abstract Preview: Purpose: The full-scale russian invasion of Ukraine has caused the largest humanitarian disaster in Europe since World War II. This study identifies gaps in RT services caused by the war and outlines ...
Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman
Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University
Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul
Affiliation: The University Of Chicago, The University of Chicago
Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...
Authors: Gong Vincent Hao, Daisuke Kawahara, Jokichi Kawazoe, Yuji Murakami, Ikuno Nishibuchi, Peiying Colleen Ruan, Daguang Xu, Dong Yang
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Graduate School of Biomedical and Health Sciences, Hiroshima University, NVIDIA
Abstract Preview: Purpose:
Accurate tumor segmentation in head and neck cancer is critical for effective treatment planning, but variability in practices across medical facilities poses challenges for standardizatio...
Authors: David L. Barbee, Jose R. Teruel Antolin, Jinyu Xue
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This work introduces a method of regional dose evaluation of normal brain tissue using local target-specific evaluation and compares to global dose evaluation for linac-based single-isocenter...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....
Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...
Authors: Hoyeon Lee
Affiliation: University of Hong Kong
Abstract Preview: Purpose: Deep-learning approaches are widely investigated for Cone-Beam CT (CBCT) scatter correction to improve the quality of the linear-accelerator mounted CBCT. This study aims to optimize the deep...
Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center
Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.
Methods: Clonogenic cell survival w...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: George X. Ding, Kenneth L. Homann
Affiliation: Vanderbilt University Medical Center
Abstract Preview: Purpose: It is standard practice that the beam monitor units (MUs) calculated by a commercial treatment planning system (TPS) is verified by a secondary dose calculation (SDC) software that independen...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: To evaluate how tin-filtered spectral shaping in clinical photon-counting computed tomography (PCCT) affects noise magnitude across varying object sizes, radiation doses, and spectral reconst...
Authors: Liang-Hsin Chen, Hsiang-Kuang Tony Linag
Affiliation: National Taiwan University Cancer Center, Department of Biomedical Engineering, National Taiwan University
Abstract Preview: Purpose: The characteristics of scanning proton beam is one of crucial factors to affect dose delivering accuracy in proton theray. Therefore, this study aims to evaluate and monitor the stability of ...
Authors: Aditya P. Apte, Joseph O. Deasy, Yusuf Emre Erdi, Anqi Fu, Johannes Hertrich, Andrew Jackson, Usman Mahmood, Jason Ocana, Trahan Sean, Amita Shukla-Dave
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Automated AI-based quantitative CT tools hold immense promise for advancing clinical decision-making, yet their reproducibility and generalizability remain vulnerable to variability in imagin...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...
Authors: Jing Qian, Brandon Reber, David M. Routman, Satomi Shiraishi
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The dose distribution in proton radiotherapy (PRT) is characterized by sharp gradients, posing a challenge for machine learning-based dose prediction. While denoising with diffusion processes...
Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang
Affiliation: RefleXion Medical
Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...
Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk
Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center
Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...
Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Demonstrating the feasibility of dose escalation for stereotactic recurrent head and neck (RHN) cancers through the deployment of a Hyper-Arc Based RapidPlan (HARP) model through an Eclipse S...
Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...
Authors: Saad Bin Saeed Ahmed, Marcos Feijoo, Wazir Muhammad, Charles Shang, Naseem Ud Din
Affiliation: South Florida Proton Therapy Institute, Miami Cancer Institute, Blue Physics LLC, Florida Atlantic University
Abstract Preview: Purpose: Accurate, efficient, and reliable commissioning of linear accelerator (LINAC) is critical for ensuring high-quality radiation therapy treatments. The study uses advanced detector technology a...
Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh
Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.
Methods: Two ultrasonic transducers position...
Authors: Renxin Chu, Jelena Mihailovic, Kai Yang, Lifeng Yu, Da Zhang
Affiliation: Massachusetts General Hospital, Mayo Clinic, Boston Children's Hospital, UVA Health University Hospital, University of Missouri Health Care
Abstract Preview: Purpose:
A frequently used method to estimate effective dose (ED) in CT is by multiplying the dose length product (DLP) by a conversion factor, known as k-factor. The k-factor in this method is sus...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Dose prediction (DP) is essential in guiding radiotherapy planning. However, current DP models for intensity-modulated radiation therapy (IMRT) primarily rely on fixed-beam orientations and a...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...
Authors: Ming Dong, Carri K. Glide-Hurst, Behzad Hejrati, Joshua Pan, Yuhao Yan
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright patient positioners and vertical CT reduce tumor motion and stabilize internal anatomy during treatment delivery. Yet, to fully exploit the advantages of upright, translation of stand...
Authors: Clara Ferreira, Tomas Agustin Montenegro, Courtney C. Oare
Affiliation: University of Minnesota
Abstract Preview: Purpose: This work provides a simulated proof of concept for the use of intravitreal gold nanoparticle (AuNP) during eye plaque brachytherapy as a radiation shield to critical structures in the eye us...
Authors: Julia Brosch-Lenz, Munir Ghesani, Francesc Massanes, Michael Morris, Babak Saboury, Eliot Siegel, Alexander Hans Vija
Affiliation: Institute of Nuclear Medicine, Siemens Medical Solutions USA Inc., Molecular Imaging
Abstract Preview: Purpose: Quantitative imaging of the radiopharmaceutical distribution is crucial for treatment evaluation and dosimetry. However, as patient numbers for Lutetium-177-(177Lu)-labelled therapies continu...
Authors: Claus Belka, Stefanie Corradini, Christopher Kurz, Guillaume Landry, Matteo Maspero, Adrian Thummerer, Erik van der Bijl
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Radboud University Medical Center, UMC Utrecht
Abstract Preview: Purpose: To automatically harmonize non-standardized organ-at-risk (OAR) structure names from multi-lingual, multi-institutional radiotherapy datasets using state-of-the-art open-source reasoning larg...
Authors: Shira Abraham, Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Phillip G. Lichtenwalner, Chuan Zeng, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
We have developed a tool that uses deformable image registrations to perform deformable dose accumulation. In this work we evaluate use of this tool for adaptive head and neck dose accumul...
Authors: Yi An, David J. Carlson, Zhe (Jay) Chen, Jun Deng, Dae Yup Han, Sameer Taneja
Affiliation: Yale School of Medicine, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Spine Stereotactic radiosurgery (SSR) delivers a large radiation dose and utilizes narrow PTV margins, on the order of 1 mm, to avoid excess dose to the spinal cord. Because of this, intrafra...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...
Authors: Minsong Cao, Amar Kishan, Dylan P. O'Connell, Jonathan Pham, Michael Steinberg, Luca F Valle, Michael Xiang
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: To evaluate bladder ultrasound as a surrogate for estimating on-table bladder volume in prostate cancer patients undergoing stereotactic body radiation therapy (SBRT). The study aimed to asse...
Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray
Affiliation: University of California San Diego
Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...
Authors: Jared Baggett, Wesley E. Bolch, Lukas M. Carter, Robert Joseph Dawson, Laura Dinwiddie, Gunjan Kayal, Adam Leon Kesner, Harry Marquis, Juan Camilo Ocampo Ramos, Stefan Wehmeier
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, University of Florida, MD Anderson
Abstract Preview: Purpose: Accurate organ dose estimation in computed tomography (CT) has gained attention due to the increasing global utilization of CT imaging. MIRDct, a specialized CT dosimetry software, has recent...
Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison
Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...
Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...
Authors: Dong Wook Kim, Jin Sung Kim, Dongho Lee, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
Abstract Preview: Purpose:
This study aims to analyze the characteristics of a novel detector based on a dielectric layer (Vieworks Co., Korea), which demonstrates high tolerance to high radiation doses and light tr...
Authors: Michael Evan Chaga, Timothy Chen, Shabbar Danish, Jesse Feng, Joseph Hanley, Georg A. Weidlich
Affiliation: Zap Surgical, Tenafly High School, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the validation of ZapMU for independent check of dose calculation is performed, ut...
Authors: Klaus Bacher, Louise D'hondt, Jeff Rutten, Gwenny Verfaillie
Affiliation: Ghent University
Abstract Preview: Purpose: Manual organ segmentation is a very time-consuming but necessary process in personalized dosimetry. Automatic segmentation tools may alleviate this task. In this study the impact of automatic...
Authors: Go Akamatsu, Hiroaki Ikawa, Yuma Iwao, Han Gyu Kang, Masashi Koto, Hideyuki Mizuno, Akram Mohammadi, Makoto Shinoto, Minoru Tajiri, Hideaki Tashima, Chie Toramatsu, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In-beam positron emission tomography (PET), in which positron emitters produced through fragmentation reactions are visualized, is a practical method for range verification in particle therap...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Rama Bhawani, Mary Joan, Ajay Katake, Munish Kumar, Chhape Ram, Megha Sharma, Balbir Singh, Vikram Singh
Affiliation: SLBSGMC & HOSPITAL, MOHANDAI OSWAL HOSPITAL, WOCKHARDT HOSPITAL, Christian Medical College and Hospital,, AMERICAN ONCOLOGY INSTITUTE
Abstract Preview: Purpose: This study aims to evaluate the utility of voxel-based radiobiological modelling in assessing IMRT radiotherapy treatment plans concerning radiation-induced acute mucosal toxicity, specifical...
Authors: Duncan Henry Bohannon, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
4D robust optimization, incorporating additional images (e.g., maximum inhale/exhale phases), is commonly used to account for target motion in proton treatment planning. However, the incre...
Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...