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Results for "Fei Han": 128 found

3D Wideband Late Gadolinium-Enhanced MRI for Radiotherapy of Ventricular Tachycardia: A Preliminary Study in Healthy Participants and Patient

Authors: Arash Bedayat, Jason Bradfield, Minsong Cao, Robert K Chin, Huiming Dong, J Paul Finn, Fei Han, Justin Hayase, Shu-Fu Shih, Xiaodong Zhong

Affiliation: Cardiac Electrophysiology, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Siemens Healthineers

Abstract Preview: Purpose: Cardiac SBRT is a promising treatment for ventricular tachycardia (VT). Success depends on accurate target delineation, for which 2D narrowband late gadolinium-enhanced (LGE) MRI offers valua...

A 2D Discrete Ionization Chamber Array for Proton Pencil Beam Scanning Flash Dosimetry

Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou

Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica

Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...

A Causal Machine Learning Analysis of Dosimetric and Clinical Predictors of Osteoradionecrosis in Head and Neck Cancer Radiotherapy

Authors: Jingyuan Chen, Sheng Li, Tianming Liu, Wei Liu, Zhengliang Liu, Zhong Liu, Daniel Ma, Samir H. Patel, Guangya Wang, Yunze Yang

Affiliation: University of Miami, Mayo Clinic, School of Data Science, University of Virginia, School of Computing, University of Georgia, Department of Radiation Oncology, Mayo Clinic, Institute of Western China Economic Research, Southwestern University of Finance and Economics

Abstract Preview: Purpose:
Traditional patient outcome analyses relied heavily on conventional statistical models that primarily elucidate correlation rather than causal relationships. In this study, we aim to ident...

A Conditional Point Cloud Diffusion Model for Deformable Liver Motion Tracking Via a Single Arbitrarily-Angled X-Ray Projection (PCD-Liver)

Authors: Yunxiang Li, Hua-Chieh Shao, Chenyang Shen, Jing Wang, Jiacheng Xie, Shunyu Yan, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Accurate liver deformable motion tracking is essential in image-guided radiotherapy to enable precise tumor targeting during treatment. We developed a conditional point cloud diffusion model ...

A Dosimetric Investigation into the Potential of Aperture-Based Techniques to Improve the Clinical Outcomes of Single-Energy Proton Bragg Peak Flash Therapy for Ocular Cancers

Authors: Arpit M. Chhabra, J Isabelle Choi, Minglei Kang, Haibo Lin, Hang Qi, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Xingyi Zhao, Ajay Zheng

Affiliation: New York Proton Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose:
Pencil beam scanning (PBS) proton therapy effectively treats ocular cancer by minimizing exit doses to normal tissues. However, challenges remain in sparing nearby organs-at-risk(OARs). Ul...

A Multi-Criteria Optimization Method Based on Reinforcement Learning and Adaptive Boosting in Radiation Therapy

Authors: Liqin HU, Tao He, Jing JIA, Pengcheng LONG, Wei Meng, Yang Yuan

Affiliation: SuperAccuracy Science & Technology Co. Ltd.

Abstract Preview: Purpose: A multi-criteria optimization method based on reinforcement learning and adaptive boosting(RLAB MCO) has been developed to enhance radiotherapy plan quality by offering reasonable and effecti...

A Multimodal CAD System for Breast Cancer Detection: Integrating MRI, DBT, and Mammography for Dense Breast Challenges

Authors: Si-Wa Chan, Yuan-Yu Lee, Zhi-Ying Li, Jia-Wei Liao, Hui-Yu Cathy Tsai

Affiliation: Department of Radiology, Taichung Veterans General Hospital​, Institute of Nuclear Engineering and Science, National Tsing Hua University

Abstract Preview: Purpose: Dense breast tissue reduces the sensitivity of mammography, posing diagnostic challenges, especially for Asian women with high breast density (up to 50%). Current single-modality techniques o...

A Novel Device for Radiation Therapy Machine Quality Assurance

Authors: Jonathan Dowell, Grace Francis, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Iridesce Solutions, Inc.

Abstract Preview: Purpose: A novel radiation therapy quality assurance (RT QA) device has been designed, constructed and tested. The nüFilmTM machine QA system provides a method for collecting light, mechanical and rad...

A Novel Semi-Analytic Approach for Dose Calculation in Proton Minibeam Radiotherapy

Authors: Hao Gao, Wangyao Li, Yuting Lin, Chao Wang, Wei Wu

Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Proton minibeam radiation therapy (pMBRT) delivers a unique peak-and-valley dose pattern using collimators with narrow slits, offering improved normal tissue sparing compared to conventional ...

A SAM-Guided and Match-Based Semi-Supervised Segmentation Framework for Medical Imaging

Authors: Weiguo Lu, Jax Luo, Xiaoxue Qian, Hua-Chieh Shao, Guoping Xu, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Harvard Medical School

Abstract Preview: Purpose:
Semi-supervised segmentation leverages sparse annotation information to learn rich representations from combined labeled and label-less data for segmentation tasks. This study leverages th...

A Tumor Tracking Method in Surface-Guided Radiotherapy

Authors: Penghao Gao, Zejun Jiang

Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...

AI-Based Registration-Free 3T T2-Weighted MRI Synthesis Using Truefisp MRI Acquired on a 0.35T MR-Linac System

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...

Absorption and Material Property Characteristics of 3D-Printing Filaments Based on Monte-Carlo Simulations and Spectral Imaging

Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon

Affiliation: University of Florida College of Medicine, University of Florida

Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...

Accuracy Analysis of "Sphere-Mask" Optical Positioning System in Radiotherapy of Breast Cancer

Authors: Xiu tong Lin, Tao Sun

Affiliation: Department of Radiation physics and technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation physics and technology, Shandong Second Provincial General Hospital

Abstract Preview: Purpose: To compare the positioning accuracy and time efficiency of "Sphere-Mask" Optical Positioning System (OPS) and traditional laser light positioning method in breast cancer radiotherapy, and to ...

An Adaptive Radiotherapy Strategy Study Based on Segmented Synthesis and Deformational Registration

Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong

Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology

Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...

An Analytical Approach to Monitor Unit Calculation in Extended Distance Total Body Irradiation (TBI)

Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav

Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine

Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...

An Automated Solution to Staged Treatments for Arteriovenous Malformations in Gammaknife

Authors: Strahinja Stojadinovic, Robert Timmerman, Yulong Yan

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Radiosurgery for large (>10cc) arteriovenous malformations (AVMs) poses significant challenges due to increased risks of complications and lower obliteration rates. To mitigate toxicity, larg...

An Explainable Classifier for Enhancing the Quality Assurance of Digital Breast Tomosynthesis Phantom Images

Authors: Hui-Shan Jian, Yu-Ying Lin

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: The image quality assurance of mammographic images is crucial for correct diagnosis. To develop and validate an explainable deep-learning classifier for phantom image quality assessment of di...

An Initial Simulation Study Towards the Patient-Specific Estimation of Stopping Power Ratio and Sound Velocity Using Protoacoustics: A Sensitivity Matrix Method

Authors: Ye Chen, Koki Kasamatsu, Taeko Matsuura, Taichi Murakami

Affiliation: Hokkaido University, National Institutes for Quantum Science and Technology (QST)

Abstract Preview: Purpose: In proton therapy, CT-based estimation of the stopping power ratio (SPR) is a significant source of range uncertainty. Protoacoustics have been developed to estimate the range in vivo, but fe...

An Integrated Robust Inverse Planning Based on AI-Built Dose Kernel Library for Preclinical Radio-Neuromodulation Using Focused Kv X-Rays

Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,

Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...

Assessing Long-Term Stability of Parylene-Coated, 3D-Printed Plastic Vessels for Water Calorimetry-Based Radiation Dosimetry

Authors: Philip Cutter, Mark D'Souza, Arman Sarfehnia

Affiliation: Toronto Metropolitan University, Sunnybrook Health Sciences Centre, Sunnybrook Health Science Center

Abstract Preview: Purpose: Water calorimetry (WC) serves as an important standard for measuring absorbed dose to water, an essential metric in radiation therapy. WC directly and absolutely quantifies energy deposition ...

Assessment of the Dosimetric Characteristics of Brass Mesh Bolus in Electron Radiation Therapy

Authors: Hungcheng Hank Chen, Laura A. Doyle, Helena Frisbie-Firsching, Amy S. Harrison, Jackson D Reeves, Lindsay B Romak, Jon Strasser

Affiliation: Christiana Care

Abstract Preview: Purpose: Brass mesh bolus (BMB) is a high-density woven metal mesh which is an excellent alternative to tissue equivalent bolus in photon beams, offering improved surface conformality. Unlike utilizat...

Automated Full-Body Tumor Segmentation from PET/CT Images

Authors: Austin Castelo, Xinru Chen, Caroline Chung, Laurence Edward Court, Jaganathan A Parameshwaran, Zhan Xu, Jinzhong Yang, Yao Zhao

Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose:
To develop a deep learning-based segmentation model to automatically delineate tumors from full-body PET/CT images.
Methods:
PET/CT image pairs of 91 patients were collected for this...

Automatic Specific Absorption Rate (SAR) Prediction for Hyperthermia Treatment Planning (HTP) Using Deep Learning Method

Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...

Automating Protocol-Specific Chart Checking in Radiotherapy

Authors: Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie

Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose:
Chart checking in radiotherapy ensures treatment plans meet clinical and safety standards. For patients in clinical trials, protocol-specific requirements add complexity, making manual rev...

Automating Radiographic Sharp Score Prediction in Rheumatoid Arthritis Using Multistage Deep Learning Methods

Authors: Hajar Moradmand, Lei Ren

Affiliation: University of Maryland School of Medicine, University of Maryland

Abstract Preview: Purpose:
The Sharp-van der Heijde (SvH) score is essential for assessing joint damage in rheumatoid arthritis (RA) from radiographic images. However, manual scoring is time-intensive and prone to v...

BEST IN PHYSICS IMAGING: Cross-Contrast Diffusion: A Synergistic Approach for Simultaneous Multi-Contrast MRI Super-Resolution

Authors: Yifei Hao, Wenxuan Li, Xiang Li, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Yaogong Zhang

Affiliation: Duke University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Diffusion-based deep-learning frameworks have been recently used in MRI resolution enhancement, or super-resolution. Multi-contrast MRI share common anatomical structures while holding comple...

BEST IN PHYSICS MULTI-DISCIPLINARY: Foundation Model-Empowered Unsupervised 3D Deformable Medical Image Registration

Authors: Xianjin Dai, PhD, Zhuoran Jiang, Lei Ren, Lei Xing, Zhendong Zhang

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, Stanford University, Duke University, Stanford University

Abstract Preview: Purpose: Unsupervised deep learning has shown great promise in deformable image registration (DIR). These methods update model weights to optimize image similarity without necessitating ground truth d...

BEST IN PHYSICS THERAPY: Fast and Convenient Proton Pencil Beam Energy QA with Multi-Layer Faraday Cup (MLFC)

Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania

Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...

Beam Orientation Optimization in IMRT Using Sparse Mixed Integer Programming and Non-Convex IMRT Fluence Map Optimization

Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center

Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...

Biomechanically Guided Deep Learning for Deformable Multimodality Liver Registration Framework

Authors: Yunfei Dong, Dongyang Guo, Zhenyu Yang, Fang-Fang Yin, Zeyu Zhang

Affiliation: Duke University, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose:
To develop a Biomechanically Guided Deep Learning Registration Network (BG-DRNet) that improves both accuracy and physiological plausibility in liver image registration. While cone-beam CT...

Brachyplancheck: An Independent Monte Carlo Dose Calculation Tool for Brachytherapy Using Egs_Brachy

Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...

CNN-Based Visualization for Detecting Failure Patterns of Lung SBRT through CT-Biological Effective Dose Interaction

Authors: Ashok Bhandari, Kurtis Johnson, Yu Lei, Tianzhe Li, Kyuhak Oh, Shuo Wang, Chi Zhang, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: The purpose of this study was to leverage neural network visualization tools to detect high-attention areas indicative of treatment failure in lung SBRT by examining correlation matrices betw...

Centralizing Resources with a Microsoft-Based Wiki Platform: Enhancing Collaboration and Efficiency in Radiation Oncology

Authors: Simon Brundage, Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie, Xiaofeng Zhu

Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology

Abstract Preview: Purpose:
Managing departmental policies, clinical protocols, QA procedures, workflows, and troubleshooting documentation is critical in radiation oncology. A Microsoft-based wiki platform was devel...

Cerebellar Mutism Syndrome Prediction with 3D Residual Convolutional Neural Network

Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki, Bohua Wan

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Department of Computer Science, Johns Hopkins University

Abstract Preview: Purpose: Cerebellar mutism syndrome (CMS) is the most frequently observed complication in children undergoing surgical resection of posterior fossa tumors. Previous work explored lesion to symptom map...

Characterizing a VMAT Optimization Algorithm with Integrated Static-Angle Modulated Ports for Esophageal Cancer Treatment

Authors: Lei Dong, Yin Gao, Taoran Li, Michael Salerno, Boon-Keng Kevin Teo, Melissa Vila

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: A novel solution, RapidArc Dynamic-RAD (Varian Medical Systems, Palo Alto, USA) has been implemented to integrate VMAT with modulation of IMRT-like static-angle ports, including use of a dyna...

Clinical Outcomes of Gamma Knife Stereotactic Radiosurgery Treatments for Intracranial Arteriovenous Malformations & Fistulas: A Single Institutional Retrospective Study

Authors: Madeleine Arbogast, David Dorndos, Denise E Foltz, Justin Fraser, Damodar Pokhrel, William St Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Department of Neurosurgery, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: For stereotactic radiosurgery (SRS) treatments of intracranial arteriovenous malformations (AVM) and fistulas (AVF), same-day Leksell Gamma Knife (GK) is the preferred modality. Long-term cli...

Clinically Ready Simulation Package for Monitoring Gamma Hotspot Emission, and Detection in Patient Anatomy

Authors: Ananta Raj Chalise, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang

Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc

Abstract Preview: Purpose: Prompt gamma (PG) imaging is a promising modality for proton dose verification. Currently, there is a lack of effective tool to investigate the PG emission during proton therapy and optimize ...

Comparison of AI-Based and Ants for Longitudinal Deformable Image Registration in Head and Neck Cancer

Authors: Aditya P. Apte, Joseph O. Deasy, Jue Jiang, Nancy Lee, Sudharsan Madhavan, Nishant Nadkarni, Lopamudra Nayak, Harini Veeraraghavan, Wei Zhao

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To track early response to radiotherapy using digital twins, it is crucial to quantify tumor volume and mass changes. Traditional tumor detection methods, particularly in image registration, ...

Comparison of Image Quality and Radiation Dose Among Four Vendors of Mobile Digital Radiography Systems

Authors: Nathalie Correa, Janet Ching-Mei Feng, Chun-Han Huang, Jimmy Huynh

Affiliation: UTHealth McGovern Medical School

Abstract Preview: Purpose: To compare the image quality and the dose-area product (DAP) of four mobile digital radiography (DR) systems—Canon (Soltus 500), Shimadzu (MobileDaRt Evolution MX8), Solution for Tomorrow (M1...

Comparitive Case Analysis of Maa Mapping and Angiographic Iodinated Contrast for Y-90 SIRT Treatment Planning

Authors: Shengwen Deng, Sven L. Gallo, Robert S. Jones, David W. Jordan, Arashdeep Kaur, Aishwarya M. Kulkarni, Quibai Li, William R.M. Pedersen

Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University; Department of Radiology, Louis Stokes Cleveland VA Medical Center

Abstract Preview: Purpose:
Y-90 (Yttrium) SIRT radioembolization takes advantage of delivering localized radiation to the liver. Pre-treatment dosimetry is highly dependent on accurate MAA mapping, which may have an...

Conversion Coefficients from Hp(10) to Organ and Effective Doses for Medical Staff Involved in Fluoroscopically Guided Interventional Procedures

Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller

Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration

Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...

Deep Learning-Based Eye Monitoring and Tracking System for Ocular Proton Therapy in a Regular Gantry Room

Authors: David H. Abramson, Christopher Barker, Jasmine H. Francis, Meng Wei Ho, Yen-Po Lee, Haibo Lin, Hang Qi, Andy Shim, Charles B. Simone, Weihong Sun, Xiaoxuan Xu, Siyu Yang, Francis Yu, Anna Zhai

Affiliation: College of Machine Intelligence, Nankai University, New York Proton Center, Department of Biomedical Engineering, Johns Hopkins University, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Proton therapy is an effective modality for treating ocular tumors such as uveal melanoma. We developed a novel camera‐based eye‐tracking system to provide real-time noninvasive eye positioni...

Deep Learning-Based Fast CBCT Imaging with Orthogonal X-Ray Projections for Gynecological Cancer Radiotherapy

Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang

Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...

Deep Learning-Based Ventricular Auto-Segmentation for Dosimetric Analysis in Intraventricular Tumor SRS

Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...

Deep-Learning Convolutional Neural Network-Based Breast Cancer Localization for Mammographic Images: A Study on Simulated and Clinical Images

Authors: Xiaoyu Duan, Xiang Li, Wenbo Wan, Lei Zhang, Yiwen Zhang

Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Breast screening has been proved to reduce breast cancer mortality by early detection and treatment for patients. Mammography is the most common and widely used technique for breast cancer sc...

Detector Physics-Incorporated Diffusion Denoising Models for Digital Breast Tomosynthesis with Dual-Layer Flat Panel Detectors

Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao

Affiliation: Stony Brook Medicine, Massachusetts General Hospital

Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...

Determining Optimal Delivery Pattern for Reference Dosimetry in Pencil Beam Scanning Proton Therapy

Authors: Clifford Ghee Ann Chua, Calvin Wei Yang Koh, Kah Seng Lew, Zubin Master, Sung Yong Park, Hong Qi Tan, Andrew Wibawa

Affiliation: National Cancer Centre Singapore

Abstract Preview: Purpose: To investigate the impact of spot position deviation on reference dosimetry measurements using different delivery patterns and to determine the optimal delivery pattern for reference dosimetr...

Development and Clinical Validation of a Tissue Maximum Ratio (TMR)-Based Monitor Units Second Check Script for Dynamic Conformal-Based Hyperarc Brain Radiosurgery Plans Via Scatter Correction Factors

Authors: Jacob Gooslin, Ellis Lee Johnson, Damodar Pokhrel

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: HyperArc radiosurgery permits treatment of multiple brain lesions using a single-isocenter improving treatment planning efficiency and workflow. A key stereotactic planning aspect is an indep...

Development of a Computational Immunohistochemical Stained Tissue Analysis of Intracellular Flash Induced Radiochemical Oxygen Depletion

Authors: Najah Curtis, Michele M. Kim, Cameron Koch, Ioannis I Verginadis, Rodney D. Wiersma, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, UCLA

Abstract Preview: Purpose: FLASH has been shown to have increased normal tissue sparing compared to standard dose rate radiation and, separately, has been shown to rapidly consume oxygen intercellularly in vivo through...

Development of a Fast Quality Assurance Software Tool for Helical Online Adaptive Radiation Therapy

Authors: Guang-Pei Chen, Mi Huang, Haidy G. Nasief, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Recently, kV imaging has been integrated into the Accuray Radixact platform, facilitating online adaptive and scan-plan-treat workflows with helical delivery in the near future. In order to s...

Development of a Knowledge-Based Planning Model for Optimal Trade-Off Guidance in Locally Advanced Non-Small Cell Lung Cancer

Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...

Development of an Eclipse Scripting API-Based Toolbox for Automated Planning in Non-Small Cell Lung Cancer: Feasibility and Validation Study

Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
This study aims to develop and validate an Eclipse Scripting Application Programming Interface (ESAPI)-based planning toolbox that incorporates preset human expertise to improve planning e...

Discriminative Uncertainty Learning for Cancer Classification

Authors: Wei Wei, Yading Yuan

Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology

Abstract Preview: Purpose: To investigate an uncertainty modeling method to improve the performance of cancer classification with the ability to produce uncertainty score.
Methods: Deep learning has achieved state-o...

Do We Need Pediatric-Specific Models for Radiotherapy Auto-Contouring? a Comparative Study of Pediatric and Adult-Trained Tools

Authors: Gregory T. Armstrong, James E. Bates, Christine V. Chung, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Meena S. Khan, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Taylor Meyers, Tucker J. Netherton, Constance A. Owens, Arnold C. Paulino, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: Clinical workflows often rely on auto-segmentation tools trained on adult data, which may exhibit suboptimal performance in pediatric imaging due to inherent anatomical variations and smaller...

Dosemorph: A Study on Few-Shot Learning and Dose-Anatomy Registration for Radiotherapy Optimal Dose Prediction in Cervical Cancer

Authors: Xiance Jin

Affiliation: 1st Affiliated Hospital of Wenzhou Medical University

Abstract Preview: Purpose:
Deep learning deformable registration models was proposed to predict optimal dose distributions a with a few of optimal planned doses using a few-shot learning for cervical cancer.
Meth...

Dosimetric Changes of Magnetic Control System to Improve Anatomy in Abdominal SBRT

Authors: Justus Adamson, Wesley Andrew Cunningham, Chang-Sei Kim, Yeongoh Ko, Anna E. Rodrigues

Affiliation: Duke University, Chonnam National University, Duke University Medical Center

Abstract Preview: Purpose: Radiation induced toxicities in bowel remains a challenge for SBRT. Due to sharp dose falloffs, small displacements of the bowel can lead to meaningful dose reduction. Remote magnetic navigat...

Dosimetric Evaluation of Comprehensive Motion Management in 1.5T MR-Linac for Real-Time Gated Radiotherapy

Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Pak Hang Nam, Mei Yan Tse, Jierong Wang, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung

Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: Intrafraction motion management remains a major challenge in magnetic resonance-guided radiotherapy (MRgRT). The recent clinical release of an active motion management system aims to enhance ...

Dosimetric Evaluation of the Aldo Function for Multiple Brain Metastases in Automated Stereotactic Radiosurgery Treatment Planning

Authors: Hsiao-Mei Fu, Shih-Ming Hsu, Chia-Ting Lee, Shih-Hua Liu, Tsung-Yu Yen

Affiliation: National Yang Ming Chiao Tung University, Mackay Memorial Hospital

Abstract Preview: Purpose: The Automatic Lower Dose Objective (ALDO) is a unique function designed to achieve 98% relative coverage across all targets in automated SRS treatment planning (HyperArc planning). This study...

Dosimetric Validation and Algorithmic Limitations of Pencil Beam Scanning Proton Therapy for Thin Chest-Wall Treatments

Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng

Affiliation: New York Proton Center, Scarsdale High School

Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...

Dual-Energy CT Derived Perfusion Blood Volume and 4D-CT Derived Ventilation Changes in Lung Cancer Patients 6-Months Post Radiation Therapy

Authors: Daniel A. Alexander, Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Casey Hollawell, William Levin, Maksym Sharma, Boon-Keng Kevin Teo, Ying Xiao, Nikhil Yegya-Raman, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: To investigate lung function changes following definitive chemoradiation dose using CT-derived measurements in patients with locally advanced NSCLC at 6-months post-treatment compared to pre-...

Effect of Variation in the α/β of Cervical Cancer on Clinical Outcomes of Radiation Therapy

Authors: Dennis A. Cheek, Wei Luo, Cameron Thayer-Freeman, Brien Timothy Washington

Affiliation: UT Southwestern Medical Center, University of Kentucky, Department of Radiation Medicine, University of Kentucky

Abstract Preview: Purpose: To investigate the effect of variation in the α/β of cervical cancer on clinical outcome for cervix cancer patients treated with radiation therapy.
Methods: A distribution of experimentall...

Effects of Communication with Patients on Bladder Sparing in Photon Beam Prostate Treatments

Authors: Nathaniel Haas, David Pearson

Affiliation: University of Toledo

Abstract Preview: Purpose: For external beam treatments for prostate cancer, we ask patients to attend treatments with their bladders full. A full bladder has been shown to reduce the dose to the bladder and bowels for...

Efficient Denoising of Low-Statistic Influence Matrices Using a Diffusion Transformer-Based Framework for Adaptive Proton Therapy

Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora

Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...

Efficient Monte Carlo Proton Dose Calculation Using Denoising Diffusion Probabilistic Models

Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...

Enhance Four-Dimension Cone-Beam Computed Tomography (4D-CBCT) from Sparse Views Using a Novel Deep Learning Model

Authors: Lei Ren, Jie Zhang

Affiliation: University of Maryland School of Medicine

Abstract Preview: Purpose: 4D-CBCT is valuable for imaging anatomy affected by respiratory motions to guide radiotherapy delivery. However, 4D-CBCT often has undersampled projections acquired in each respiratory phase ...

Enhancing Dosimetric Conformity in Single-Energy Bragg Peak Flash Therapy Using Aperture-Based Techniqu

Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda

Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...

Evaluating Commercial Auto-Segmentation Software: Is Performance on Pediatric Organs-at-Risk Accurate?

Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...

Evaluating Tumor Shrinkage Using Fractionated Radiotherapy: A Mixed Finite Element Method (FEM) for Free Boundary Problem

Authors: Xianjin Dai, PhD, Xiang Wan, Lei Xing, Qiuyun Xu, Lewei Zhao, Zeyu Zhou

Affiliation: Department of Radiation Oncology, Stanford University, Carl Zeiss X-ray Microscopy, Department of Mathematics and Statistics, Loyola University Chicago, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: The purpose of this study is to examine and quantify tumor shrinkage over time in response to fractionated radiotherapy. We seek to establish a predictive model that can provide a systematic ...

Evaluating the Efficacy and Efficiency of Spine Treatment Using Diagnostic CT

Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy

Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics

Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...

Evaluation of Daily Respiratory Pattern from a Single Free-Breathing Cone Beam CT Scan

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patients’ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...

Evaluation of Deformable Image Registration Accuracy Used in MR-Only Ventilation Mapping

Authors: Fei Han, James M. Lamb, Michael Vincent Lauria, Daniel A. Low, Tessa Elizabeth Maurer, Danilo Maziero, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Nicolas Viot

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Siemens Healthineers, UCLA, University of California Los Angeles

Abstract Preview: Purpose: Patients with lung disease outside radiotherapy are barred from high dose protocols used for motion modeling, but MRI could offer no-dose alternatives. Image-based ventilation is a promising ...

Evaluation of Target Localization Accuracy As a Function of CBCT Acquisition Speed

Authors: Kuan Ling Chen, Jiajin Fan, Maduka M. Kaluarachchi, Wei Nie

Affiliation: Inova Schar Cancer Institute

Abstract Preview: Purpose: This study evaluates the impact of CBCT acquisition speed on the accuracy of moving target alignment during image-guided radiotherapy. Additionally, the influence of target motion speed and r...

Explainable AI with Attention Gates for Transparent and Interpretable Lung Radiotherapy Plan Evaluation

Authors: Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Yin Gao, Xun Jia, Kevin Teo, Lingshu Yin, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, Johns Hopkins University

Abstract Preview: Purpose: Understanding how physicians evaluate plans is critical for automatic planning and ensuring consistent, high-quality care. While deep-learning models excel in complex decision-making, the lac...

Explainable Xerostomia Prediction with Decoupled High Resolution Class Activation Map

Authors: Junghoon Lee, Todd R. McNutt, Harry Quon, Bohua Wan

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Department of Computer Science, Johns Hopkins University

Abstract Preview: Purpose: Xerostomia is a common toxicity in head and neck cancer (HNC) radiotherapy (RT). A few deep learning (DL) models have been proposed to predict the chance of xerostomia 12 months after RT with...

Feasibility of Real-Time Monitoring in Tumor Treating Fields Therapy Using Electrical Impedance Tomography: Analysis of Current Injection and Measurement Patterns

Authors: Sung Hwan Ahn, Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, Hyeongjin Lim, Sang Yoon PARK, Myonggeun Yoon

Affiliation: Institute of Global Health Technology (IGHT), Korea University, Republic of Korea, Korea University, Samsung Medical Center

Abstract Preview: Purpose:
This study aims to evaluate the feasibility of real-time monitoring of conductivity changes induced by thermal variations during tumor treating fields (TTFields) therapy using Electrical I...

Fine-Tuning AI-Based Generative Models for Small-Sample Glioma MRI Generation.

Authors: Xiangli Cui, Chunyan Fu, Man Hu, Wanli Huo, Jingyu Liu, Jianguang Zhang, Yingying Zhang, Shanyang Zhao

Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, Department of Oncology, Xiangya Hospital, Central South University, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences

Abstract Preview: Purpose: To quantify the impact of fine-tuning strategies for pre-trained AI image generation models on glioma MRI image quality and observer performance, and to determine the optimal fine-tuning conf...

Free-Breathing Spirometer-Gated Proton Pencil Beam Scanning Delivery Maintains Tumor Coverage with Improved Organ-at-Risk Sparing: A Motion Phantom Validation

Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng

Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...

GPU Accelerated Monte Carlo Simulation for Tset Dose Calculation

Authors: Veng Jean Heng, Jan P. Seuntjens, Timothy C. Zhu, Yifeng Zhu

Affiliation: Department of Radiation Oncology, Stanford University, Princess Margaret Cancer Centre & University of Toronto, University of Pennsylvania

Abstract Preview: Purpose: We have developed a GPU-accelerated Monte Carlo (MC) simulation to determine the cumulative dose distribution of patients undergoing Total Skin Electron Therapy (TSET) using the Stanford tech...

Generation of Patient-Specific Phantom for Head & Neck Proton Therapy Based on Xcat

Authors: Cheng-En Hsieh, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu, An-Ci Yang

Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou

Abstract Preview: Purpose:
The aim of this study is to develop a framework of generating patient-specific phantom tailored for head and neck proton therapy. From these phantoms, digital reference objects based on th...

Graph Neural Network with Long Short-Term Memory for CT-Based Macrotrabecular-Massive Hepatocellular Carcinoma Diagnosis

Authors: Enhui Chang, Yunfei Dong, Yifei Hao, Chengliang Jin, Shengsheng Lai, Yi Long, Mengni Wu, Yulu Wu, Ruimeng Yang, Zhenyu Yang, Yue Yuan, Lei Zhang, Wanli Zhang, Yaogong Zhang

Affiliation: Duke Kunshan University, Department of Radiology, The Second Affiliated Hospital, School of Medicine, South China University of Technology, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Macrotrabecular-Massive Hepatocellular Carcinoma (MTM-HCC) is one type of liver cancer showed minimum image signature for accurate non-invasive diagnosis. This study aims to develop and evalu...

High Resolution Head Motion Correction Based on Pilot Tone Signals – a Calibration-Free Method

Authors: Cheng-Chieh Cheng, Jeffrey P Guenette, Yajun Li, Bruno Madore, Lei Qin

Affiliation: Brigham and Women's Hospital, National Sun Yat-sen University, Dana-Farber Cancer Institute

Abstract Preview: Purpose: Pilot tone (PT), a compact RF sensor, has been integrated into clinical practice for motion detection. Prior studies proposed mapping PT signals to head positions using a calibration step tha...

Identifying Candidates for Endobronchial Valve (EBV) Treatment for Patients with Moderate to Severe Emphysema: Exploring the Use of Estimated Lung Elasticity Using a Biomechanically Based Model Derived from CT Image Data

Authors: Ryan Andosca, Peter Boyle, Grace Hyun Kim, Minji Victoria Kim, Michael Vincent Lauria, Michael F. McNitt-Gray, Gabriel Melendez-Corres, Jack Neylon, Brad Stiehl, Pang Yu Teng

Affiliation: David Geffen School of Medicine at UCLA, University of California, Los Angeles, UCLA Department of Radiology, Department of Radiation Oncology, University of California, Los Angeles, UCLA, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Endobronchial Valves (EBV) are one of the few treatment options for patients with moderate to severe emphysema. Eligibility is typically assessed from CT image data analysis including Emphyse...

Image Quality Enhancement for Transrectal Ultrasound Imaging of Prostate Brachytherapy Using Deep Learning: A Needle Eraser

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...

Impact of IMRT Beam Scatter and Electronic Noise on Real-Time Kv and Fluoroscopy Image Quality

Authors: Wei Luo, Cameron Thayer-Freeman, Yifeng Zhao

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky

Abstract Preview: Purpose: Real-time Kilovoltage (kV) imaging has emerged as a powerful clinical aid, providing high-precision localization of moving targets during treatment. However, the Megavoltage (MV) treatment be...

Impact of Respiratory Motion and MRI Sequences on Tumour Volume Determination in MR-Guided Radiotherapy

Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu, Chi To Yung

Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose:
The Elekta Unity system facilitates daily adaptive radiotherapy using MRI-based treatment planning. However, MR images are prone to motion artefacts caused by respiratory motion, potential...

Impact of Tissue Heterogeneity on Proton LET and RBE Distributions: A Monte Carlo Study

Authors: Xiangli Cui, Wei Han, Jie Li, Lingling Liu

Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences

Abstract Preview: Purpose: To investigate the influence of tissue heterogeneity on proton beam linear energy transfer (LET) and relative biological effectiveness (RBE) using nine RBE models. This study quantifies the i...

Improvements from Monte Carlo Simulations over Pencil Beam Algorithms for Normal Tissue Dose Reconstruction in Proton Therapy Patients

Authors: Amy Berrington de Gonzalez, Keith T Griffin, Jae Won Jung, Cari M Kitahara, Choonik Lee, Choonsik Lee, Aimee L McNamara, Matthew Mille, Harald Paganetti, Sergio Morato Rafet, Jan PO Schuemann, Jungwook Shin, Torunn I Yock

Affiliation: University of Michigan, East Carolina University, Massachusetts General Hospital, National Cancer Institute, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Massachusetts General Hospital and Harvard Medical School, Institute of Cancer Research

Abstract Preview: Purpose: Radiotherapy dose reconstruction enables retrospective epidemiological studies that connect late health effects to the organ-absorbed radiation doses received during treatment. Though clinica...

Initial Comparison of 3D CBCT Performance: New Mobile C-Arm Vs. O-Arm Unit

Authors: Wendy Siman, Wei Zhou

Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine

Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...

Intraoperative Dynamic Contrast-Enhanced Fluorescence Imaging in Quantifying Tissue Perfusion of Amputation Patients

Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang

Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center

Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...

Investigation of the Diagnostic Quality of Chest X-Rays Simulated from CT

Authors: Matthew R. Hoerner, Allison Shields

Affiliation: Yale University School of Medicine, Yale University

Abstract Preview: Purpose: To investigate the quality and clinical utility of chest x-rays synthesized from CT scans (sCXR).
Methods: Five helical chest CT exams were chosen for evaluation: this cohort represented a...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

Latent Diffusion Model-Driven Semi-Supervised Semantic Segmentation of Cell Nuclei

Authors: Mark Anastasio, Hua Li, Zhuchen Shao

Affiliation: Washington University School of Medicine, University of Illinois Urbana-Champaign

Abstract Preview: Purpose: Automated semantic segmentation of cell nuclei in microscopic images is vital for disease diagnosis and tissue microenvironment analysis. However, obtaining large annotated datasets for train...

Longitudinal CMR Strain Analysis of Right Ventricular (RV) Function across Aging in Offspring of Baboons Exposed to Moderate Maternal Undernutrition

Authors: Geoffrey D. Clarke, Laura A. Cox, Alexander J Moody, Peter W Nathanielsz, Bowen Yang

Affiliation: Wake Forest University School of Medicine, University of Texas Health Science Center at San Antonio, Texas Biomedical Research Institute

Abstract Preview: Purpose:
Recent studies show diagnostic value of myocardial strain analysis for left ventricular (LV) function using cardiac magnetic resonance imaging (CMR). RV function analysis is more challengi...

MR-Based Functional Liver Imaging and Dosimetry to Predict Albi Change Post-SBRT

Authors: Madhava Aryal, James M. Balter, Yue Cao, Daniel T Chang, Kyle Cuneo, Joseph R. Evans, Theodore Lawrence, John Rice, Randall K. Ten Haken, Lise Wei

Affiliation: University of Michigan, Department of Radiation Oncology University of Michigan

Abstract Preview: Purpose: This study aims to identify predictors of global liver function change measured by albumin-bilirubin (ALBI) score following stereotactic body radiation therapy (SBRT) in hepatocellular carcin...

MRI Radiomics-Based Machine Learning Model for Predicting BNCT Treatment Response in Glioblastoma

Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying

Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital

Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...

Modeling Alpha-Particle Dose from Diffusing Alpha-Emitters Radiation Therapy in Tissue with Inhomogeneous Diffusion

Authors: Lior Arazi, Gil'ad N. Cohen, Antonio L. Damato, Irene P. Zhang

Affiliation: Unit of Nuclear Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, NYU Grossman School of Medicine, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Diffusing alpha-emitters Radiation Therapy (ā€œAlpha DaRTā€) is a promising new radiation therapy modality for treating bulky tumors. The dose delivered by Alpha-DaRT sources is dependent on the...

Modernization of the NIST Air-Kerma Strength Standard for LDR Brachytherapy Seeds

Authors: Michael G. Mitch, Csilla I. Szabo-Foster

Affiliation: National Institute of Standards and Technology

Abstract Preview: Purpose: The U.S. air-kerma strength standard for low-dose-rate (LDR) low-energy photon-emitting brachytherapy sources provides measurement traceability for calibrations at the AAPM Accredited Dosimet...

Multi-Mechanism CNN and Long Short-Term Memory Fusion Model for Improved CT-Based Thyroid Cancer Diagnosis

Authors: Yunfei Dong, Dongyang Guo, Jiongli Pan, Tao Peng, Caiyin Tang, Zhenyu Yang, Fang-Fang Yin, Lei Zhang, Tianyi Zhang, Yaogong Zhang

Affiliation: Duke Kunshan University, Department of Radiology, Taizhou People’s Hospital Affiliated to Nanjing Medical University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aims to improve the accuracy of CT-based diagnosis of thyroid cancer by developing a hybrid model that integrates Convolutional Neural Networks (CNNs) with Long Short-Term Memory (...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. 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Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. 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San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

Needle-in-Needle Technique: A Lifeline for HDR Syed Interstitial Implants with Unusable Catheters

Authors: Jochen Cammin, Yushi Chang, Mariana Guerrero, Kai Jiang, Narottam Lamichhane, Elizabeth Nichols

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine

Abstract Preview: Purpose: Our institution handles a large GYN SYED patient load (5 HDR fractions over 3 days). In recent years, we faced many logistical challenges, such as broken/contaminated catheters, which disrupt...

Non-Invasive Photoacoustic Thermometry for Real-Time Monitoring of Tissue Temperature Using Frequency Analysis

Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar

Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Northwestern University, Medical College of Georgia, Augusta University

Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...

Objective Verification of Mechanical and Radiation Isocenters Independent of Setup

Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy

Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.

Abstract Preview: Purpose: The novel machine quality assurance (QA) device nüFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...

Online Active Learning Strategies for Global Medical Physics Education: A Scoping Review

Authors: Mary Gronberg, Kelly Kisling, Ana Maria Marques da Silva

Affiliation: University of California, San Diego, The University of Texas Southwestern Medical Center, Pontifical Catholic University of Rio Grande do Sul

Abstract Preview: Purpose: To evaluate the current status of online teaching in medical physics and identify effective active learning strategies for global medical physics education.
Methods: A scoping review was c...

Optimizing Dose Coverage and Mitigating Electron Return Effects and Electron Stream Effects in MR-Linac Treatment of Extremity Malignancies: The Impact of Bolus and Gel Use

Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Darren M. C. Poon, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study investigates optimal treatment strategies utilizing MR-linac for extremity lesions, with a specific focus on a 0.6 cm deep lesion in the right palm. The magnetic field-induced dose...

Pancrea-Seg-Net: A Semi-Supervised Deep Learning Framework for Pancreatic Tumor and Vessel Segmentation

Authors: Manju Liu, Ning Wen, Fuhua Yan, Yanzhao Yang, Zhenyu Yang, Haoran Zhang, Lei Zhang, Yajiao Zhang

Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy where precise segmentation of tumors and adjacent vessels is crucial for effective treatment planning. This study dev...

Patient-Specific Ultra-Sparse k-Space Reconstruction Using Motion Decomposition and Sinusoidal Representation Networks for Dynamic Volumetric MRI in Radiotherapy

Authors: Karyn A Goodman, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Qian Wang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Beth Israel Deaconess Medical Center

Abstract Preview: Purpose: Accurate motion management in MRI-guided radiotherapy (MRIgRT) relies on real-time volumetric MRI to track intra-fractional anatomical changes. Dense k-space sampling, while capable of produc...

Performance Evaluation of CT-Based Lung Tumor Classification Deep Learning Algorithms Under Centralized and Federated Learning Frameworks

Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou

Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...

Physics-Informed Neural Network for In Vivo Dosimetry during Proton Therapy Using Protoacoustic Tomography

Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu

Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center

Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...

Precision Radiotherapy Dose Prediction Using Foundation Model-Augmented Learning

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Xianjin Dai, PhD, Praveenbalaji Rajendran, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School

Abstract Preview: Purpose: Artificial intelligence (AI)-driven methods have transformed dose prediction, streamlining the automation of radiotherapy treatment planning. However, traditional approaches depend exclusivel...

Prediction of Vertebral Compression Fracture after Stereotactic Body Radiotherapy for Spinal Metastases Using Clinical, Radiomic and Dosiomic Features

Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki

Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine

Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...

Proton Pencil Beam Scanning Ultra-High Dose Rate 3D Lattice Radiotherapy: A Proof-of-Concept Flash Sfrt Study

Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng

Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...

Proton Vs Photon Therapy for Stereotactic Arrhythmia Radioablation of Ventricular Tachycardia

Authors: Chih-Wei Chang, Kristin A Higgins, Xiaojun Jiang, Pretesh Patel, Justin R. Roper, Keyur Shah, Sibo Tian, Zhen Tian, Yinan Wang, Xiaofeng Yang, Jun Zhou

Affiliation: Department of Radiation Oncology, City of Hope Cancer Center Atlanta, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Ventricular tachycardia (VT) is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. Stereotactic arrhythmia...

Rapid CBCT Imaging with Ultra-Sparse X-Ray Projections for Head & Neck Cancer Radiotherapy

Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou

Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...

Real Time Monte Carlo Dose Calculation for Clinical Cyberknife Radiation Therapy Based on Deep Learning Diffusion Model

Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang

Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...

Real-Time Proton and Carbon Ion Monte Carlo Dose Calculation through GPU-Acceleration and DL-Based Denoising Algorithms

Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao

Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.

Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...

Realistic Modeling of Vasculature Flow and Oxygen Distribution in Normal Tissue and Glioblastoma

Authors: Yi Fan, Andrew Friberg, Costas Koumenis, Kevin Teo, Ioannis I Verginadis, Ledi Wang, Jennifer Wei Zou

Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania

Abstract Preview: Purpose: Glioblastomas (GBM) are aggressive and lethal malignancies characterized by their highly refractory nature, contributing to a five-year survival rate of approximately 7%. Physically, GBM exhi...

Region-Specific Structure-Function Coupling Alterations in Parkinson’s Disease: Insights from Multi-Modal MRI

Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu

Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinson’s disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...

Scissor-Beam Based Carbon Ion Minibeam Treatment Planning Method

Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang

Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...

Simulating Realistic Digital Phantoms for Virtual Clinical Trials in Radiology and Radiation Oncology Using a Deep-Learning Based Conditional Denoising Diffusion Probabilistic Model (c-DDPM)

Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong

Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...

Streamlined Calibration of Mosfet Dosimeters for Radixact Systems: Addressing Angular Dependence and Beam Profile Challenges

Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...

Teach What You See: Incorporating Theranostics Curriculum into Medical Physics Resident Education

Authors: Isaac J. Bailey, Lindsay S. DeWeese, Anna M. Mench, Celeste Winters

Affiliation: Oregon Health & Science University, Department of Diagnostic Radiology, Oregon Health & Science University

Abstract Preview: Purpose: The emergence and recent FDA approval of several new radiopharmaceutical therapies have increased demand for physicists to provide specialized support. However, these topics are not yet inclu...

Text-Conditioned Latent Diffusion Model for Synthesis of Contrast-Enhanced CT from Non-Contrast CT

Authors: Yizheng Chen, Michael Gensheimer, Mingjie Li, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Automatically translating non-contrast to contrast-enhanced computed tomography (CT) images is critical for improving clinical workflow, reducing heathcare cost, minimizing radiation exposure...

The Comparison of Radiation Uses in Common Procedures Amongst Didactic Pediatric Fluoroscopic Units

Authors: Janet Ching-Mei Feng, Jimmy Huynh

Affiliation: UTHealth McGovern Medical School

Abstract Preview: Purpose: The Image Gently Alliance had provided helpful information to optimize image protocols in pediatric patients since 2007, and our assumption was that newer units could use near-to-optimal prot...

The Impact of Intempo Imaging on Cyberknife Prostate Plans

Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu

Affiliation: Thomas Jefferson University

Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...

Ultra-Sparse-View Cone-Beam CT Reconstruction Based Strictly-Structure-Preserved Deep Neural Network in Image-Guided Radiation Therapy

Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang

Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University

Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...

Using Open-Source Reasoning Large Language Models for Radiotherapy Structure Name Harmonization

Authors: Claus Belka, Stefanie Corradini, Christopher Kurz, Guillaume Landry, Matteo Maspero, Adrian Thummerer, Erik van der Bijl

Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Radboud University Medical Center, UMC Utrecht

Abstract Preview: Purpose: To automatically harmonize non-standardized organ-at-risk (OAR) structure names from multi-lingual, multi-institutional radiotherapy datasets using state-of-the-art open-source reasoning larg...

Web-Based Tool for CT Ring Artifact Identification Using Streamlit and Python

Authors: Sarah Huo, David Zander, Wei Zhou

Affiliation: Cherry Creek High School, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, School of Medicine

Abstract Preview: Purpose:
Ring artifact is commonly seen in CT, and it is usually caused by detector element failure or miscalibration. Although many ring artifacts are apparent and easy to recognize, those origina...