Authors: Ishika Bhaumik, John M. Boone, Michael T Corwin, Eric S Diaz, Ahmadreza Ghasemiesfe, Andrew M. Hernandez, Sarah E. McKenney, Misagh Piran, Ali Uneri, Eric L White
Affiliation: UC Davis, UC Davis Health, University of California, Johns Hopkins Univ
Abstract Preview: Purpose: A new model CT scanner (Canon Aquilion One Insight) was recently installed at our institution, and it included a 3D Landmark (3DLM) scan for automatic scan planning, a new deep learning recon...
Authors: Arash Bedayat, Jason Bradfield, Minsong Cao, Robert K Chin, Huiming Dong, J Paul Finn, Fei Han, Justin Hayase, Shu-Fu Shih, Xiaodong Zhong
Affiliation: Cardiac Electrophysiology, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Siemens Healthineers
Abstract Preview: Purpose: Cardiac SBRT is a promising treatment for ventricular tachycardia (VT). Success depends on accurate target delineation, for which 2D narrowband late gadolinium-enhanced (LGE) MRI offers valua...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Sixue Dong, Weigang Hu, Jiazhou Wang, Zhen Zhang
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the dosimetric benefits and treatment efficiency of different beam configurations in 4π non-coplanar VMAT for SBRT in recurrent head and neck tumors
Method...
Authors: Steve Braunstein, Yannet Interian, Hui Lin, Bo Liu, Janine Lupo, Olivier Morin, Benedict Neo
Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Data Science, University of San Francisco, University of San Francisco
Abstract Preview: Purpose: Large Language Models (LLMs) demonstrate strong general text comprehension but remain limited in oncology due to insufficient contextual alignment. We pilot embedding alignment through radiol...
Authors: Hao Peng, Yajun Yu
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel ablative radiation dosing scheme developed by our institution. This study aims to establish a regression...
Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr
Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...
Authors: Sorour Hosseini, YuHuei Jessica Huang, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To evaluate image quality—including noise, contrast-to-noise ratio (CNR), uniformity, and low-contrast visibility (LCV)—on the HyperSight and TrueBeam cone-beam computed tomography (CBCT) pla...
Authors: Yunxiang Li, Hua-Chieh Shao, Chenyang Shen, Jing Wang, Jiacheng Xie, Shunyu Yan, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate liver deformable motion tracking is essential in image-guided radiotherapy to enable precise tumor targeting during treatment. We developed a conditional point cloud diffusion model ...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Gregory Szalkowski, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Respiratory motion management is crucial for accurate radiation delivery to moving targets while protecting healthy tissue, relying on time-resolved volumetric imaging and continuous deformab...
Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Jamieson Baker, Emel Calugaru, Yijian Cao, Jenghwa Chang, Jessica Jung, Jian Liu, Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke
Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health, Hofstra University Medical Physics Program
Abstract Preview: Purpose: Our hospital network has options to treat recurrent glioblastoma (GBM) with surgically targeted Cesium-131 brachytherapy, external beam stereotactic radiotherapy (SRT) with Varian TrueBeam, H...
Authors: Travis James McCaw, Ravi Patel, Abdelhamid Saoudi, Joseph Shields
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, UPMC
Abstract Preview: Purpose: The current treatment approach for Lu-177-based radiopharmaceutical therapy involves multiple administrations, each delivering a constant activity of 200 mCi. This study evaluates whether the...
Authors: Jie Deng, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Based on a 3D pre-treatment MRI scan, we developed DREME-MR to jointly reconstruct the reference patient anatomy and a data-driven, patient-specific cardiorespiratory motion model. Via a moti...
Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2D–3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Christos Ilioudis, Marios Myronakis, Sotirios Raptis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Department of Information and Electronic Engineering, International Hellenic University (IHU)
Abstract Preview: Purpose: This study presents a radiomics-driven, machine learning framework developed to predict the possibility of Radiation Pneumonitis (RP), as a side effect of radiation therapy in lung cancer pat...
Authors: Wenfeng He, Tian Liu, Pretesh Patel, Richard L.J. Qiu, Keyur Shah, Tonghe Wang, Xiaofeng Yang, Chulong Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Emory University, Medical Physics Graduate Program, Duke Kunshan University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study introduces a tracking-free approach to reconstruct 3D ultrasound (US) volumes from 2D freehand US scans. By eliminating the reliance on external tracking systems, this method aims ...
Authors: Beth M. Beadle, Adrian Celaya, Laurence Edward Court, David Fuentes, Anna Lee, Tze Yee Lim, Dragan Mirkovic, Amy Moreno, Raymond Mumme, Tucker J. Netherton, Callistus M. Nguyen, Jaganathan A Parameshwaran, Jack Phan, Carlos Sjogreen, Sara L. Thrower, Congjun Wang, He C. Wang, Xin Wang
Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, Stanford University, The University of Texas MD Anderson Cancer Center, MD Anderson Cancer Center, MD Anderson, Rice University, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Quality assurance of target volumes from radiotherapy clinical trials is a labor and resource intensive task. The purpose of this work is to quantify the accuracy of a tool that automatically...
Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...
Authors: Laura Bennett, Wesley S. Culberson, Albert Du, Kevin J. Erhart, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care, .decimal
Abstract Preview: Purpose: To develop and experimentally validate a novel Monte Carlo (MC) framework designed to enable calculation-based quality assurance (QA) for collimated intensity modulated proton therapy treatme...
Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...
Authors: Si-Wa Chan, Yuan-Yu Lee, Zhi-Ying Li, Jia-Wei Liao, Hui-Yu Cathy Tsai
Affiliation: Department of Radiology, Taichung Veterans General Hospital, Institute of Nuclear Engineering and Science, National Tsing Hua University
Abstract Preview: Purpose: Dense breast tissue reduces the sensitivity of mammography, posing diagnostic challenges, especially for Asian women with high breast density (up to 50%). Current single-modality techniques o...
Authors: Jiayun Chen, Shengqi Chen, Yuan Tang, Zilin Wang, Guohua Wu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose:
To develop a novel no-reference image quality assessment (NRIQA) method for evaluating the effectiveness of image preprocessing in MRI-guided radiotherapy (MRIgRT), thereby enhancing clini...
Authors: Reza Farjam, Russell K Hales, Seth Jayawardane, Todd R. McNutt, Mohammad Rezaee, Ehsan Tajikmansoury, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins School of Medicine
Abstract Preview: Purpose: This study presents a novel cost-effective customizable 3D-printed phantom developed for end-to-end treatment verification and image-quality assessment for thoracic applications.
Methods: ...
Authors: Ahad Ollah Ezzati, Yile Fang, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: With breast cancer being one of the most prevalent cancers, regular screening is an effective strategy to mitigate the risk of malignancy. However, conventional energy-integrating detector (E...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Weiguo Lu, Hua-Chieh Shao, Guoping Xu, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Neural network-based lesion segmentation remains a significant challenge due to the low contrast between lesions and surrounding tissues (high ambiguity) and the variability of lesion shap...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital
Abstract Preview: Purpose: This study quantitatively evaluates the interplay effect in intensity-modulated proton therapy (IMPT) for lung cancer stereotactic body radiotherapy (SBRT) using two different machine deliver...
Authors: Yuli Lu, Chendong Ni, Cheng Qian, Kun Qian, Weiwei Sang, Chunhao Wang, Fan Xia, Zhenyu Yang, Fang-Fang Yin, Rihui Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Duke University, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: To develop a radiomic quantification framework to evaluate the effects of radiomic image preprocessing hyperparameters (i.e., image resampling and discretization) on texture characterization ...
Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma
Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...
Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao
Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...
Authors: Zijia Guo, Michael F. McNitt-Gray, Frederic Noo, Karl Stierstorfer
Affiliation: Siemens Healthineers, University of Utah, David Geffen School of Medicine at UCLA
Abstract Preview: Purpose: Accurately assessing lung parenchyma health is critically important in the management of patients with chronic obstructive pulmonary disease. CT attenuation values are valuable for this purpo...
Authors: Weiguo Lu, Jax Luo, Xiaoxue Qian, Hua-Chieh Shao, Guoping Xu, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Harvard Medical School
Abstract Preview: Purpose:
Semi-supervised segmentation leverages sparse annotation information to learn rich representations from combined labeled and label-less data for segmentation tasks. This study leverages th...
Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...
Authors: Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of California, Irvine
Abstract Preview: Purpose: To achieve the full-view image from a single-view sinogram using a two-stage deep learning model for electroacoustic-tomography (EAT), which is an emerging imaging technique with significant ...
Authors: Xiangli Cui, Man Hu, Wanli Huo, Da Yao, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
To study the fine-tuning strategy of pre-trained AI image generation model to adapt to the generation of small sample meningioma MRI images, explore its impact on observer performance, and...
Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu
Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...
Authors: Zachary Buchwald, Chih-Wei Chang, Richard L.J. Qiu, Mojtaba Safari, Hui-Kuo Shu, Lisa Sudmeier, Xiaofeng Yang, David Yu, Xiaohan Yuan
Affiliation: Emory University and Winship Cancer Institute, Emory University, Georgia Institute of Technology, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study proposes a novel vision-language model (VLM) to predict survival outcomes in glioblastoma (GBM) patients. By integrating multimodal MRI data and clinical information, the proposed ...
Authors: Zachary Buchwald, Zach Eidex, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Gadolinium-based contrast agents (GBCA) are commonly used for patients with gliomas to delineate and characterize the brain tumors using T1-weighted (T1W) MRI. However, there is a rising conc...
Authors: Weigang Hu
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose: The purpose of this study is to introduce a VQVAE-based framework that addresses the limitations of conventional dose prediction methods, which rely on fixed deep learning models that produce...
Authors: Mojtaba Behzadipour, Siyong Kim, Mitchell Polizzi, Richard R. Wargo, Lulin Yuan
Affiliation: VCU Health - Department of Radiology, Virginia Commonwealth University
Abstract Preview: Purpose:
The purpose of this study is to develop a method for generating missing tissue in CT scans of patients with large body sizes, where the field of view (FOV) of the scanner fails to capture ...
Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl
Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...
Authors: Mu-Han Lin
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: The rapid expansion of AI in Radiation Oncology is reshaping patient care, treatment planning, and institutional investments. Yet, with no standardized framework for evaluating cost-effectiveness, saf...
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
We propose a method to optimize adaptive proton FLASH therapy (ADP-FLASH) using modularized pin-ridge filters (pRFs) by recycling module pins from the initial plan, reducing pRF adjustment...
Authors: Aman Anand, Jonathan B. Ashman, Martin Bues, Brady S. Laughlin, Lisa McGee, Justin Pettit, Fan Yang, Libing Zhu
Affiliation: Department of Radiation Oncology Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: Proton therapy (PT) offers significant clinical and economic benefits across various cancers, whereas it also has faced skepticism due to its historically high costs and perceived overuse in ...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Richard L.J. Qiu, Mojtaba Safari, Shansong Wang, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: MRI offers excellent soft tissue contrast for diagnosis and treatment but suffers from long acquisition times, causing patient discomfort and motion artifacts. To accelerate MRI, supervised d...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou People’s Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Zachery Colbert, Matthew Foote, Michael Huo, Mark Pinkham, Prabhakar Ramachandran, Mihir Shanker
Affiliation: Radiation Oncology, Princess Alexandra Hospital, Ipswich Road, Princess Alexandra Hospital
Abstract Preview: Purpose: The study aimed to develop and implement deep learning-based autosegmentation models for the autosegmentation of four key tumor types: brain metastasis, pituitary adenoma, vestibular schwanno...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory
Abstract Preview: Purpose:
Dual-layer kV imager (DLI) architecture enables the capability for single-shot dual-energy (DE) intrafraction imaging. As noise from individual DLI layers are primarily uncorrelated, simpl...
Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...
Authors: Hao Gao, Xue Hong, Harold Li, Yuting Lin, Jufri Setianegara, Xin Tong, Chao Wang, Weijie Zhang, Ya-Nan Zhu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high radiation doses to specific tumor regions (vertices) while sparing surroun...
Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing
Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,
Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...
Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu
Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell
Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...
Authors: Lu Jiang, Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: In radiotherapy, the conformity and compactness of dose distribution are vital to patient outcomes. The introduction of highly complex planning, such as 4π radiotherapy, has provided a system...
Authors: John T Barrett, Mehnaz Haque, Chulhaeng Huh, Shands James, Thomas B. Lavin, Anobel Maghsoodpour, Farshad Mostafaei, Austin Sanders
Affiliation: Department of Radiation Oncology, Augusta University, Department of Radiation Oncology, Medical College of Georgia, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health, Department of Radiation Oncology, Doctors Hospital of Augusta, Department of Radiology and Imaging, Augusta University
Abstract Preview: Purpose: This study assesses Philips’ O-MAR effectiveness in adjusting AVHU values of common anatomical materials affected by various high-density metal artifacts at varying distances.
Methods:...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Sophie Bockel, Eric Deutsch, Frederic Dhermain, Ibrahima Diallo, Anh Thu Le, Elaine Limkin, Pauline Maury, Charlotte Robert, Killian Sambourg, Camilla Satragno, Cristina Veres, François de Kermenguy
Affiliation: Gustave Roussy, Département de radiothérapie, Université Paris-Saclay, Gustave Roussy, Inserm U1030, Radiothérapie Moléculaire et Innovation Thérapeutique
Abstract Preview: Purpose:
To study the correlation between the dose to circulating lymphocytes as evaluated by the LymphoDose framework and the incidence of severe radiation-induced lymphopenia (sRIL) in patients t...
Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate delineation of treatment targets and organs-at-risk is crucial for radiotherapy. Despite significant progress in artificial intelligence (AI)-based automatic segmentation tools, effi...
Authors: Mylinh Dang, Laila A Gharzai, Xinlei Mi, Poonam Yadav
Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine
Abstract Preview: Purpose: Delineation of organs at risk (OAR) in the head/neck region requires substantial physician time. Many artificial intelligence (AI) based auto-contouring software are commercially available. T...
Authors: Zachary M. Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: High spatial resolution in pin ridge filter (pRF)-based proton planning may be constrained by the 1mm dose grid resolution in commercial treatment planning systems. This study investigates th...
Authors: Xinhua Li, Vu Nguyen, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Assessing iodine concentration in liver lesions is essential for evaluating contrast enhancement in multi-phase liver CT and for accurate disease diagnosis. This study aims to evaluate the as...
Authors: Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Nancy Y Lee, Anyi Li, Jung Hun Oh, Teeradon Treechairusame, Pengpeng Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To automatically monitor weekly anatomical changes of parotid glands during adaptive radiotherapy of head and neck cancers, systematically assess the relationship between parotid gland shrink...
Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson
Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions
Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...
Authors: Yan Chu, Madison Emily Grayson, Radhe Mohan, Pablo P. Yepes
Affiliation: UT Health Science Center at Houston, Rice University, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Radiation-induced lymphopenia (RIL) is a common adverse effect of radiation therapy, negatively impacting overall survival and anti-PD1 immunotherapy efficacy. Our lab previously developed a ...
Authors: Chuangxin Chu, Haotian Huang, Tianhao Li, Jingyu Lu, Zhenyu Yang, Fang-Fang Yin, Tianyu Zeng, Chulong Zhang, Yujia Zheng
Affiliation: The Hong Kong Polytechnic University, Nanyang Technological University, Australian National University, Medical Physics Graduate Program, Duke Kunshan University, North China University of Technology, Duke Kunshan University
Abstract Preview: Purpose: Deep learning segmentation models, such as U-Net, rely on high-quality image-segmentation pairs for accurate predictions. However, the recent increasing use of generative networks for creatin...
Authors: Srinivas Cheenu Kappadath, James Long, Armeen Mahvash, Anna Marks, Ajalaya Teyateeti
Affiliation: Mahidol University, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Alpha-fetoprotein (AFP) has been implicated as prognostic factor of overall survival (OS) for hepatocellular carcinoma (HCC). We present a statistical approach to determine optimal AFP-cut...
Authors: Shahed Badiyan, Tsuicheng D. Chiu, Viktor M. Iakovenko, Steve Jiang, Christopher Kabat, Mu-Han Lin, Roberto Pellegrini, Arnold Pompos, Edoardo Salmeri, David Sher, Sruthi Sivabhaskar, Justin D. Visak
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Global Clinical Science, Elekta AB, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Adaptive treatment planning requires robust strategies to enable streamlined on-couch processes, creating a significant barrier for planners transitioning from conventional to adaptive planni...
Authors: Izabella L. Barreto, Aroon Pressram
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: Our clinical dual energy CT (DECT) head protocol reconstructs iodine-suppressed virtual non-contrast (VNC) images using the vendor-recommended slope for material discrimination. However, this...
Authors: Hungcheng Hank Chen, Laura A. Doyle, Helena Frisbie-Firsching, Amy S. Harrison, Jackson D Reeves, Lindsay B Romak, Jon Strasser
Affiliation: Christiana Care
Abstract Preview: Purpose: Brass mesh bolus (BMB) is a high-density woven metal mesh which is an excellent alternative to tissue equivalent bolus in photon beams, offering improved surface conformality. Unlike utilizat...
Authors: Ashish Binjola, Raj Kishore Bisht, Natanasabapathi Gopishankar, Pratik Kumar, Daya Nand Kishore Sharma, Sukhvir Kishore Singh, Subramani Vellaiyan
Affiliation: Medical Physics Unit, All India Institute of Medical Sciences, All India Institute of Medical Sciences, Department of Radiological Safety, Institute of Nuclear Medicine and Allied Sciences, Department of Radiation Oncology, All India Institute of Medical Sciences
Abstract Preview: Purpose: Additive manufacturing is increasingly being explored to create dosimetry phantoms. Commercial anthropomorphic phantoms represent an average patient and lack anatomical variations due to obes...
Authors: Matthew J Ferris, Jason K Molitoris
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose: Anatomy changes often happen in head-and-neck (HN) patients treated with proton radiation therapy. These changes can result in deteriorations of target dose coverage and increased dose to org...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Hannah Grover, Andrew J. Sampson
Affiliation: Oregon Health & Science University, UT Health San Antonio
Abstract Preview: Purpose: The goal of this work was to quantify the dosimetric impact of iodinated contrast on fibroglandular breast tissue to better inform clinical risk and benefit assessments when determining the m...
Authors: Steve Braunstein, Angela Jakary, Hui Lin, Bo Liu, Janine Lupo, Tiffany Ngan, Ke Sheng, Nate Tran
Affiliation: Radiation Oncology, University of California San Francisco, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, Department of Radiation Oncology, University of California San Francisco, Department of Radiology and Biomedical Imaging, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Current RT clinical target volumes (CTVs) for Glioblastoma (GBM) employ 2cm isotropic expansions of gross tumor volumes. However, studies showed patients still experience progression beyond t...
Authors: Hua-Chieh Shao, Chenyang Shen, Jiacheng Xie, Shunyu Yan, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Motion-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection), is highly desired for regular/irregular motion chara...
Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania
Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...
Authors: Yabo Fu, Yang Lei, Yu Lei, Haibo Lin, Ruirui Liu, Tian Liu, Kenneth Rosenzweig, Charles B. Simone, Shouyi Wei, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, New York Proton Center
Abstract Preview: Purpose: Beam orientation optimization (BOO) in intensity-modulated radiation therapy (IMRT) is traditionally a complex, non-convex problem tackled with heuristic methods. This study benchmarks global...
Authors: Jiayi Du, Lihua Jin, Ke Sheng, Yu Zhou
Affiliation: Harvard University, University of California, San Francisco, UCLA, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Radiomics enables powerful insights into tumor biology through non-invasive imaging, excelling in diagnostic and prognostic predictions. However, due to a lack of mechanistic connections, que...
Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu
Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...
Authors: Humberto Monsivais, Brian A. Taylor, Francesco Versace
Affiliation: Purdue University, Department of Behavioral Science, Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To identify possible signatures of altered brain morphometry in nicotine-dependency via a structural covariance network approach.
Methods: Fifty-one healthy controls (HC:27M, mean age=...
Authors: Nana Akosua O. Adomako, Evangeline Dorleagbenu, Victor E. Ekpo, Fatima Issaka, Abigail N.M. Quaye
Affiliation: Tema General Hospital, Pink Africa Foundation, Korle Bu Teaching Hospital, Methodist University, Medical Equipment and Ancillary Services
Abstract Preview: Purpose: This preliminary study evaluates the effectiveness of breast cancer awareness programs for teenagers in Tema, Ghana. In Ghana, breast cancer poses a significant public health challenge. There...
Authors: Ryan Clark, Anthony Magliari, Luis Felipe Oliveira E Silva, Yang Sheng, Jason R Vickress, Qingrong Jackie Wu, Giulianne Rivelli Rodrigues Zaratim
Affiliation: Verspeeten Family Cancer Center, Office of Medical Affairs, Varian, A Siemens Healthineers Company, Confiar Radioterapia, Duke University Medical Center
Abstract Preview: Purpose: Develop a toolset to replace several of the tedious steps required to manually generate 3D breast treatment plans using static gantry forward planned tangent beams.
Methods: Eclipse Sc...
Authors: Ashok Bhandari, Kurtis Johnson, Yu Lei, Tianzhe Li, Kyuhak Oh, Shuo Wang, Chi Zhang, Su-Min Zhou
Affiliation: University of Nebraska Medical Center
Abstract Preview: Purpose: The purpose of this study was to leverage neural network visualization tools to detect high-attention areas indicative of treatment failure in lung SBRT by examining correlation matrices betw...
Authors: Steve B. Jiang, Mu-Han Lin, Dan Nguyen, Beiqian Qi, Daniel Yang, Ying Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Online adaptive radiotherapy (oART) is a resource-intensive workflow requiring significant time and effort required from clinicians, particularly for the online evaluation of plan quality....
Authors: Simon Brundage, Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie, Xiaofeng Zhu
Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose:
Managing departmental policies, clinical protocols, QA procedures, workflows, and troubleshooting documentation is critical in radiation oncology. A Microsoft-based wiki platform was devel...
Authors: Serdar Charyyev, Kaan Dere, Edgar Gelover, Mohammad Khurram Khan, Liyong Lin, Mark McDonald, Cristina Oancea, Alexander Stanforth, Sibo Tian, Suk Whan (Paul) Yoon, Mingyao Zhu
Affiliation: Department of Radiation Oncology, Stanford University, Stanford University, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Advacam
Abstract Preview: Purpose: The conventional implementation of proton spatially fractionated radiotherapy (SFRT) utilizes physical collimators with apertures to generate minibeams, creating alternating regions of high-d...
Authors: Brett G Erickson, Joseph P. Kowalski, Xinyi Li, Qiuwen Wu, Sua Yoo
Affiliation: Duke University, Mayo Clinic - Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: Characterization and commissioning of the BeO-based myOSLchip system was performed (per TG191) to assess its feasibility as a full replacement for the recalled Landauer aluminum oxide OSL in ...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Michael Dohopolski, Xuejun Gu, Hao Jiang, Steve B. Jiang, Christopher Kabat, Jingying Lin, Weiguo Lu, Michael Tang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Neuralrad LLC, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: To streamline access to clinical data stored in Oncology Information Systems such as MOSAIQ or ARIA, we developed an AI-powered chatbot capable of querying, summarizing, and interactively ans...
Authors: Ergun E. Ahunbay, Colette Gage, Abdul Kareem Parchur, Eric S. Paulson
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: AI-generated synthetic CT (sCT) images address challenges with prior sCT approaches, including atlas- and threshold-based methods. Commercial AI-based sCT tools have been introduced. This wor...
Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...
Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology
Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...
Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...
Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...
Authors: Minsong Cao, Amar Kishan, Yi Lao, An Liu, Beth Neilsen, X. Sharon Qi, Kun Qing, Ke Sheng, Michael Steinberg, Luca F Valle, Terence Williams
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, City of Hope Medical Center, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To investigate the clinical relevance of planned versus delivered doses in toxicity associations utilizing localized assessment of genitourinary (GU) toxicity in bladder subregions among pros...
Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...
Authors: Junsheng Cao, Luis A. Maduro Bustos, Khushdeep Singh
Affiliation: Overlook Medical Center, Atlantic Health System at Morristown Medical Center
Abstract Preview: Purpose: To evaluate the agreement between the Sun Nuclear Multi-Met Winston Lutz test (WL) and Varian’s Machine Performance Check (MPC) in assessing isocenter alignment, couch, and collimator rotatio...
Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...
Authors: Mauro Carrara, Olivera Ciraj Bjelac, John E. Damilakis, Andre L. Dekker, Serafina Di Gioia, Renato Padovani, Egor Titovich, Qingrong Jackie Wu
Affiliation: University of Crete, Duke University Medical Center, Maastro Clinic, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, International Centre for Theoretical Physics
Abstract Preview: Purpose: The purpose of this work is to present the International Atomic Energy Agency (IAEA) activity in providing medical physicists (MPs) with knowledge, skills, and competencies to support the saf...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose: Convergence speed is crucial for an optimizer. Faster convergence leads to better solutions with fewer iterations and less time. Recently, a machine learning (ML)-assisted framework employing...
Authors: Stephen Balter, Haegin Han, Cari M Kitahara, Taeeun Kwon, Choonsik Lee, Martha S Linet, Donald L. Miller
Affiliation: Columbia University Medical Center, National Cancer Institute, Food and Drug Administration
Abstract Preview: Purpose: Staff in fluoroscopically guided interventional (FGI) procedures are exposed to radiation. Inhomogeneous radiation fields and variability in procedural conditions make it challenging to deriv...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...
Authors: Stephen Bhagroo, Sorour Hosseini, YuHuei Jessica Huang, Jeremy Kunz, Thomas Boyd Martin, Geoffrey S. Nelson, Nicholas Pierre Nelson, Ryan G. Price, Hui Zhao
Affiliation: University of Utah, Department of Radiation Oncology, Huntsman Cancer Institute, University of Utah
Abstract Preview: Purpose: To investigate the correlation between HyperSight CBCT imaging dose and image quality.
Methods: Six-series of 174 CBCT scans were acquired using HyperSight on Halcyon (125kV, 133-971mAs, F...
Authors: Afrouz Ataei, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose: Even though many patients undergo diagnostic CT scans prior to treatment, simulation CT scans are commonly required for treatment planning. This study evaluates whether prior diagnostic CT sc...
Authors: Xu Chen, Jun Lian, Yunkui Pang, Pew-Thian Yap
Affiliation: University of North Carolina at Chapel Hill, Huaqiao University
Abstract Preview: Purpose: Unsupervised CBCT-to-CT translation in the pelvic region is essential for accurate radiotherapy delivery and adaptive image-guided interventions. However, current models for cross-modality tr...
Authors: Derek Tang, Susu Yan
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: To evaluate the performance of a multi-task automated-segmentation and synthetic CT generation model (sCT) and investigate its application in an adaptive proton therapy workflow.
Methods: ...
Authors: Hector Andrade-Loarca, Ines Butz, Chiara Gianoli, Prof. Gitta Kutyniok, Jianfei Li, Katia Parodi, Prof. Vincenzo Patera, Angelo Schiavi, Prof. Ozan Öktem
Affiliation: Sapienza University of Rome, Department of Mathematics, Royal Institute of Technology, School of Computation, Information and Technology, Technische Universitaet Muenchen, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Department of Mathematics, Ludwig-Maximilians-Universität (LMU) München, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München
Abstract Preview: Purpose: To explore and demonstrate the feasibility of accurate and fast prediction of the water equivalent thickness (WET) distribution of tissue traversed by a proton imaging pencil beam, aiming at ...
Authors: Zhuo Chen, Tinsu Pan, Allan Thomas
Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, WashU Medicine, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Misregistration between data-driven gated (DDG)-PET and CT can limit the benefits of motion correction and improved localization and quantitation. DDG-CT offers a solution to these issues. He...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...
Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham
Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona
Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...
Authors: Weikang Ai, Xiaoyu Hu, Xun Jia, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Real-time tumor tracking is critically important for respiratory motion management for lung cancer radiotherapy. A previously proposed application of a photon counting detector involves measu...
Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang
Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...
Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita
Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital
Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...
Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...
Authors: Xinyi Fu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Digitally reconstructed radiographs (DRRs) are easy to generate and widely used to establish research protocols in pulmonary diagnosis and image-guided radiotherapy tasks. A question remai...
Authors: Xiaoyu Duan, Xiang Li, Wenbo Wan, Lei Zhang, Yiwen Zhang
Affiliation: Duke University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: Breast screening has been proved to reduce breast cancer mortality by early detection and treatment for patients. Mammography is the most common and widely used technique for breast cancer sc...
Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic
Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...
Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...
Authors: Stephanie Bennett, Sean L. Berry, Caroline M. Colbert, Dustin J. Jacqmin, James A. Kavanaugh, Minsun Kim, Maura L. Kirk, Emily Kruse, Benjamin Li, Mu-Han Lin, Lindsey A. Olsen, Jose Carlos Pichardo, Justin R. Roper, Leah K. Schubert, Chunhao Wang, Sua Yoo
Affiliation: University of Wisconsin, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Abington - Jefferson Health, Mayo Clinic, University of Washington, University of Colorado Health, University of Colorado Denver, Department of Radiation Oncology, University of Washington and Fred Hutch Cancer Center, Duke University, Pichardo Physics LLC, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: As clinics in lower- and middle-income countries (LMICs) transition to advanced radiotherapy techniques like IMRT and VMAT, gaps in training can result in suboptimal planning. To help support...
Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Massachusetts General Hospital
Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...
Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang
Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale
Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...
Authors: Xinhui Duan, Roderick W. McColl, Mi-Ae Park, Liqiang Ren, Gary Xu, Kuan Zhang, Yue Zhang
Affiliation: UT Southwestern Medical Center, Department of Radiology, UT Southwestern Medical Center, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose:
Image-based deep-learning noise-reduction techniques have been developed for photon-counting CT (PCCT) to improve image quality with reduced radiation dose. The denoising strength is typic...
Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Julia Bauer, Tianxue Du, Katia Parodi, Marco Pinto, Thomas Tessonnier
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Heidelberg Ion Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich)
Abstract Preview: Purpose:
Carbon ion therapy could benefit from range verification due to its sensitivity to range uncertainties. Positron emission tomography (PET) aids in this and comparing irradiation-induced PE...
Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...
Authors: John Byun, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Xianghua Ye, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Neurosurgery, Stanford University, Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: Accurate and automated delineation of vestibular schwannoma (VS) volume is crucial for disease management, as both treatment approaches (stereotactic radiosurgery and invasive surgery) and mo...
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Children’s Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Children’s Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Alejandro Bertolet, Isaac Meyer, Harald Paganetti, Jan PO Schuemann, Wook-Geun Shin
Affiliation: Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a methodology for Monte Carlo modeling of cell-specific DNA geometries based on Hi-C data using TOPAS-nBio, and to evaluate early DNA damage distributions.
Methods: Hi-C data of...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojin Kim, Jin Sung Kim, HO Lee, Sac Lee, Yongdo Yun
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: Carbon ion radiotherapy (CIRT) offers the advantage of a greater relative biological effectiveness (RBE) weighted dose, which must be integrated into the treatment planning system (TPS). This...
Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo
Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...
Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan
Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China
Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...
Authors: Adam P. Berdusco, Matthew R. Ceelen, Renata Farrell, Carri K. Glide-Hurst, Will Martin, Charles F. Maysack-Landry, Morgan A. McGauley, James Rice, Jordan M. Slagowski, Yuhao Yan
Affiliation: Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Upright radiotherapy (RT) is now available although this novel vertical CT and positioner presents unique challenges for quality assurance and testing methodologies. We have designed and buil...
Authors: Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang
Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China
Abstract Preview: Purpose: To develop a proton CT system using scintillator-based 2D dose distribution detection for accurate proton imaging.
Methods: The proposed proton CT system consists of a brass collimator wit...
Authors: Kaelyn Becker, Xenia Ray
Affiliation: University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: Ethos 2.0 with HyperSight (Varian Medical Systems) imaging enables nearly fully automated offline adaptive radiotherapy including automated deformation of targets and recalculation on the Hou...
Authors: Chang Chang, Mohammad Kanber, Stephen Kenneth Northway
Affiliation: East Carolina University, California Protons Cancer Therapy Center, California Proton Cancer Therapy Center
Abstract Preview: Purpose:
Proton therapy treatment planning involves the consideration of unique physical quantities such as Linear Energy Transfer (LET) and spot location maps that do not exist in photon treatment...
Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao
Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...
Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma
Affiliation: University of Pennsylvania, Mayo Clinic
Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...
Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong
Affiliation: Massachusetts General Hospital
Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...
Authors: Robert Fucetola, Jiayi Huang, Zhihua Liu, Chongliang Luo, Tong Zhu
Affiliation: Washington University School of Medicine, Washington University in St. Louis, School of Medicine
Abstract Preview: Purpose:
This prospective observational study investigates radiation-induced white matter (WM) injuries using longitudinal diffusion tensor imaging (DTI) in patients with diffuse glioma following r...
Authors: Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz
Affiliation: UT Health San Antonio, University of Texas HSC San Antonio
Abstract Preview: Purpose: To evaluate dosimetric accuracy of Brainlab Elements (BLE) 4.0 treatment planning system (TPS) for linac based SRS and Spine SBRT treatment.
Methods: RT Safe cranial and thorax phantoms wi...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Pak Hang Nam, Mei Yan Tse, Jierong Wang, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung
Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital
Abstract Preview: Purpose: Intrafraction motion management remains a major challenge in magnetic resonance-guided radiotherapy (MRgRT). The recent clinical release of an active motion management system aims to enhance ...
Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko Salomón Alva Sánchez
Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal
Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZAP-X is the newest cranial stereotactic radiosurgery (SRS) platform. Small-volume structures usually found in the head and neck may be susceptible to dose-volume averaging, which has not bee...
Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaël Ndoutoume-Paquet, Jan P. Seuntjens, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, Princess Margaret Cancer Centre & University of Toronto, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Nuclear Medicine Department, Hospital Regional de Antofagasta, Université Laval, Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University
Abstract Preview: Purpose: Low-energy X-ray beams used in electronic brachytherapy (eBT) pose unique dosimetric challenges due to high depth-dose gradients, material-dependent detector responses, and the absence of sta...
Authors: Min Su
Affiliation: Mount Sinai School of Medicine
Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...
Authors: Min Su
Affiliation: Mount Sinai School of Medicine
Abstract Preview: Purpose: To evaluate dosimetric impact of target coverage and organ at risk (OARs) sparing for whole breast patient setup roll/yaw change in 3D-conformal radiotherapy.
Methods: 8 whole breast cases...
Authors: Nguyen Phuong Dang, Mason Hazlett, Lijun Ma, Yutaka Natsuaki, William T. Watkins, Zhengzheng Xu, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, Radiation Oncology, Keck School of Medicine of USC, RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: This is the first study reporting the beam dosimetric parameter cross-checks of Reflexion linac using different water phantom systems and detectors. The difference in measurements using diffe...
Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng
Affiliation: New York Proton Center, Scarsdale High School
Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...
Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal
Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center
Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...
Authors: Matthew Stephen Andriotty, Chi Ma, Xiao Wang, Keying (Karen) Xu, Suhong Yu, Ning J. Yue, Yin Zhang
Affiliation: Brigham and Women's Hospital, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To evaluate the effects of overlapping CT reconstruction on dosimetry calculation for LINAC-based SRS patients simulated on CT simulators from three different vendors.
Methods: CT simulati...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Daniel A. Alexander, Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Casey Hollawell, William Levin, Maksym Sharma, Boon-Keng Kevin Teo, Ying Xiao, Nikhil Yegya-Raman, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: To investigate lung function changes following definitive chemoradiation dose using CT-derived measurements in patients with locally advanced NSCLC at 6-months post-treatment compared to pre-...
Authors: Leshan Sun, Liangzhong Xiang, Yifei Xu, Yuchen Yan
Affiliation: University of California, Irvine
Abstract Preview: Purpose: X-ray Acoustic Computed Tomography (XACT) is a transformative innovation in medical imaging, overcoming the limitations of conventional X-ray techniques. It introduces new possibilities in cl...
Authors: James E. Bates, Benjamin Hopkins, Kirk Luca, Shadab Momin, Justin R. Roper, Soumon Rudra, Eduard Schreibmann, Bill Stokes, Tu Thi, Xiaofeng Yang
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Swallowing dysfunctions after radiotherapy are caused by multiple factors yet are strongly associated with the irradiation of pharyngeal musculature due to its role in the initiation and comp...
Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center
Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...
Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey
Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...
Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Gaolong Zhang
Affiliation: Department of Radiation Oncology, School of Physics, Beihang University, School of physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: In intensity-modulated proton therapy (IMPT) for head and neck cancer, CBCT registration ensures accurate setup, minimizing dose errors. Unlike IMRT, IMPT plans directly define tumor volumes ...
Authors: Jia Jing, Hui Lin, Daming Meng, Zhenyu Xiong
Affiliation: School of Physics, Hefei University of Technology, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: Artificial intelligence (AI) is attempting to understand the essence of intelligence and produce a new type of intelligent machine that can respond in a way similar to human intelligence. AI ...
Authors: Abdelfatah Abdalla Nemer Abdelsalam, Elmubarak M. Ahmed, Sarah A. Ashmeg, M. Saiful Huq, Alsadeg Awad Alamin Mohamed, Ali Sid Ahmed Mohammed, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, UPMC Hillman Cancer Center, University of Medical Science and Technology, King Abdulaziz Medical City, Department of Radiation Oncology, University of Pennsylvania, Tumor Therapy and Cancer Research Center, Al Neelain University
Abstract Preview: Purpose: Severe conflict in Sudan has led to the closure of several cancer services within the country. With new centers in development by an IAEA and Rays of Hope initiative, many barriers exist in m...
Authors: Jing Cai, Zhi Chen, Hong Ge, Yu-Hua Huang, Bing Li, Zihan Li, Ge Ren
Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital
Abstract Preview: Purpose: Algorithms based on subregional respiratory dynamics (SRD) capture spatiotemporal heterogeneity in the ventilation process, though rely on empirical modelings to map surrogate ventilation. Gi...
Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez
Affiliation: University of Miami
Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...
Authors: Jadon Buller, Zhuoran Jiang, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of California, Stanford University
Abstract Preview: Purpose: Electroacoustic tomography (EAT) and Protoacoustic (PA) imaging are novel modalities for treatment verification of electroporation and proton therapy. However, the limited acquisition angle i...
Authors: Yang Lei, Haibo Lin, Tian Liu, Charles B. Simone, Shouyi Wei, Ajay Zheng
Affiliation: Icahn School of Medicine at Mount Sinai, New York Proton Center
Abstract Preview: Purpose: Radiation-induced lung injury (RILI), encompassing pneumonitis and fibrosis, represents a critical dose-limiting factor in lung cancer radiation therapy. Variability in treatment outcomes is ...
Authors: Hassan Bagher-Ebadian, Justine M. Cunningham, Anthony J. Doemer, Mohammad M. Ghassemi, Joshua P. Kim, Benjamin Movsas, Kundan S Thind
Affiliation: Michigan State University, Henry Ford Health
Abstract Preview: Purpose: Reduction of noise in medical images critically enables improved accuracy in delineating tumors and organs at risk, leading to more precise treatment planning and safer image-guided radiation...
Authors: Mengqi Shen, Meghna Trivedi, Tony J.C. Wang, Andy (Yuanguang) Xu, Yading Yuan
Affiliation: Columbia University Medical Center, Dept of Med Hematology & Oncology, Data Science Institute at Columbia University, Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: T2-weighted (T2w) images are critical for identifying pathological changes due to their superior contrast in differentiating tissue types. However, they often lack detailed anatomical resolut...
Authors: Nan Li, Yaoying Liu, Shouping Xu, Xinlei Xu, Gaolong Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, School of physics, Beihang University, Beihang University, Department of Radiation Oncology
Abstract Preview: Purpose:
CT simulation is essential for radiation therapy preparation but has limitations in distinguishing lesions. Contrast-enhanced CT (CECT) improves lesion detection and characterization, but ...
Authors: Sarah Burleson, Antonio L. Damato, Yabo Fu, Laura Happersett, Tianfang Li, Xiang Li, Himanshu Nagar, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: An iodinated hydrogel perirectal spacer, injected between the prostate and rectum, reduces rectal high-dose exposure during prostate SBRT. We assessed the feasibility of tracking the spacer a...
Authors: Diana Cardona, Casey C. Heirman, William Jeck, Kyle J. Lafata, Xiang Li, Lauren M. Neldner, Jeffrey S. Nelson, Megan K. Russ, Ehsan Samei
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Department of Pathology, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Medical physicists have traditionally supported radiation-based medicine, but their expertise can translate to other image-based fields including pathology. As pathology transitions to digita...
Authors: Christopher Bartee, Justin Riley DeFrancisco, Marcos Feijoo, Siyong Kim, Tianjun Ma
Affiliation: Blue Physics LLC, Virginia Commonwealth University
Abstract Preview: Purpose: Irradiation with FLASH has been shown to decrease normal tissue toxicity while maintaining similar tumor control. To advance FLASH into the clinic, more preclinical investigations are first n...
Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...
Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...
Authors: Xianjin Dai, PhD, Xiang Wan, Lei Xing, Qiuyun Xu, Lewei Zhao, Zeyu Zhou
Affiliation: Department of Radiation Oncology, Stanford University, Carl Zeiss X-ray Microscopy, Department of Mathematics and Statistics, Loyola University Chicago, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: The purpose of this study is to examine and quantify tumor shrinkage over time in response to fractionated radiotherapy. We seek to establish a predictive model that can provide a systematic ...
Authors: Yi-Fang Wang, Yading Yuan
Affiliation: Columbia University Irving Medical Center, Department of Radiation Oncology, Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, the latest CBCT technology from Varian Medical Systems, integrates rapid 6-second data acquisition with advanced iterative reconstruction and upgraded hardware. Previous studies h...
Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy
Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics
Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...
Authors: Ali Ammar, Quan Chen, Yi Rong, Libing Zhu
Affiliation: Mayo Clinic Arizona
Abstract Preview: Purpose: To investigate how defacing algorithms, essential for patient privacy in data sharing, impact AI-based segmentation performance in CT imaging for radiation therapy. This study evaluates wheth...
Authors: Shinichiro Mori, Isabella Pfeiffer, Chester R. Ramsey, Alexander Usynin
Affiliation: Thompson Proton Center, National Institutes for Quantum Science and Technology, Thompson Cancer Survival Center
Abstract Preview: Purpose: Four-dimensional CT imaging (4DCT) has become a standard tool for managing respiratory motion in radiation therapy. However, many treatment delivery systems and most diagnostic CT scanners la...
Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao
Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patients’ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling, Jianling Yuan
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: To analyze volume changes in the high-risk clinical target volume (HR-CTV) during high-dose rate (HDR) brachytherapy for cervical cancer patients. The study aims to evaluate the trend and cor...
Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang
Affiliation: Northwestern Medicine
Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...
Authors: Fan Liu, Adam C. Riegel, Yi-Fang Wang
Affiliation: Columbia University Irving Medical Center
Abstract Preview: Purpose: HyperSight, Varian Medical Systems' latest CBCT technology, integrates rapid 6-second data acquisition with advanced iterative reconstruction, enabling precise real-time contouring and dose c...
Authors: Yu-Ying Lin, Yu Chen Shen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...
Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Alex T. Price, Sagar Regmi, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To investigate the feasibility and accuracy of using a Hounsfield Unit(HU) calibrated cone-beam computed tomography(CBCT) for direct dose calculation in thoracic treatment settings. In combin...
Authors: Hiroki Katayama, Hiroki Kawasaki, Motonori Kitaoka, Yosuke Takahashi, Takashi Tanii, Masato Tsuzuki
Affiliation: Kagawa University Hospital
Abstract Preview: Purpose:
Surface-guided radiotherapy (SGRT) with ExacTrac Dynamic (ETD) allows motion tracking and beam gating during treatment delivery. Accurate evaluation of beam-on and beam-off delays is essen...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu
Affiliation: Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...
Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis
Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...
Authors: Anthony Hong Cheol Lim, Rayyan L Mahmood, Alexander Stanforth, Chris C. Wang, Mingyao Zhu
Affiliation: Georgia Institute of Technology, Emory University
Abstract Preview: Purpose: The purpose of this project is to test the feasibility of proton minibeam lattice radiotherapy within an existing clinical setting.
Methods:
The TOPAS code is used to model a scenario i...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...
Authors: Xiangli Cui, Chunyan Fu, Man Hu, Wanli Huo, Jingyu Liu, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, Department of Oncology, Xiangya Hospital, Central South University, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose: To quantify the impact of fine-tuning strategies for pre-trained AI image generation models on glioma MRI image quality and observer performance, and to determine the optimal fine-tuning conf...
Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf
Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital
Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...
Authors: Niels Bassler, Jonathan Bortfeldt, Carlos Granja, Guyue Hu, Margarita Kozak, Julie Lascaud, Kirsten Lauber, Grigory Liubchenko, Jasper Nijkamp, Cristina Oancea, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Brita Singers Sørensen, Matthias Würl
Affiliation: Department of Nuclear Medicine, LMU University Hospital, LMU Munich, Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital, Advacam
Abstract Preview: Purpose: To apply in-vivo proton radiography (pRad) to aid image registration and treatment plan refinement for a novel precision image-guided small animal proton irradiation platform.
Methods:...
Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: This study introduces a novel template-guided deep learning framework for primary gross tumor volume (GTVp) segmentation, addressing challenges posed by diverse tumor types and enabling a uni...
Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...
Authors: Kwang-Ho Cheong, Seungryong Cho, Joonil Hwang, Jae Won Jung, Hoyeon Lee, Raymond Hyunwoo Moon, Inhwan Yeo, Jihyung Yoon
Affiliation: East Carolina University, INOVA Schar Cancer Institute, University of Hong Kong, Hanllym University, KAIST, University of Rochester
Abstract Preview: Purpose: Monitoring a target and neighboring organs during beam delivery is crucial for successful radiotherapy (RT). Conventional transit imaging methods lack volumetric reconstruction capabilities, ...
Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison
Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Himanshu Bhat, Bruce Lewis Daniel, Junghoon Lee, Michael B. Roumeliotis, Ehud J. Schmidt, Ravi Seethamraju, Khadija Sheikh, Pan Su, Akila N. Viswanathan
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Siemens Medical Solutions USA Inc., Stanford Medical School, Department of Cardiology, Johns Hopkins University
Abstract Preview: Purpose: To perform frequent MRI during EBRT and brachytherapy (BT) to evaluate RT-induced fibrosis and remnant tumor changes, identified using ultrashort echo-time (UTE) and multiparametric (mpMRI), ...
Authors: Elizabeth L. Covington, Robert T. Dess, Charles S. Mayo, Michelle L. Mierzwa, Dan Polan, Jennifer Shah, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan
Abstract Preview: Purpose: Auto-segmentation improves contour consistency and standardization in radiation therapy but may introduce variations from current practices, potentially impacting treatment outcomes and toxic...
Authors: Veng Jean Heng, Jan P. Seuntjens, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, Stanford University, Princess Margaret Cancer Centre & University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: We have developed a GPU-accelerated Monte Carlo (MC) simulation to determine the cumulative dose distribution of patients undergoing Total Skin Electron Therapy (TSET) using the Stanford tech...
Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko
Affiliation: RefleXion Medical, Cosylab
Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...
Authors: Nan Li, Shouping Xu, Gaolong Zhang, Xuerong Zhang
Affiliation: Department of Radiation Oncology, HeBei YiZhou proton center, School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose:
The 3D BRAVO sequence is an advanced magnetic resonance (MR) technique that allows for image reconstruction at any angle. It offers 1 mm gapless scanning and has a high signal-to-noise rat...
Authors: Rashmi Bhaskara, Shravan Bhavsar, Ananth Grama, Oluwaseyi Oderinde, Shourya Verma
Affiliation: Purdue University
Abstract Preview: Generating Synthetic Positron Emission Tomography from Computed Tomography using Lightweight Diffusion Model for Head and Neck Cancer
Purpose: To generate synthetic PET tumor avidity segments direc...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...
Authors: Rodrigo T Massera, Sofia Giaccone Thomaz, Alessandra Tomal, Giovanna Tramontin
Affiliation: Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin, Department of Imaging & Pathology, unit of Medical Physics & Quality Assessment, KU Leuven
Abstract Preview: Purpose: Monte Carlo simulations are increasingly used in breast dosimetry for their precision in estimating difficult-to-measure quantities, such as glandular dose. With ionizing radiation in breast ...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...
Authors: So Hyun Ahn, Chris Beltran, Byongsu Choi, Jeong Heon Kim, Jin Sung Kim, Bo Lu, Justin Chunjoo Park, Bongyong Song, Jun Tan
Affiliation: Mayo Clinic, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, UC San Diego, Yonsei University College of Medicine
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) is widely used in IGRT for patient positioning but suffers from low resolution and poor soft tissue contrast. Synthetic CT (sCT) generated from CBCT ad...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study introduces a novel spatiotemporal Gaussian neural representation framework to reconstruct high-temporal dynamic CBCT images from 1-minute acquisition, preserving motion dynamics an...
Authors: Ryan Andosca, Peter Boyle, Grace Hyun Kim, Minji Victoria Kim, Michael Vincent Lauria, Michael F. McNitt-Gray, Gabriel Melendez-Corres, Jack Neylon, Brad Stiehl, Pang Yu Teng
Affiliation: David Geffen School of Medicine at UCLA, University of California, Los Angeles, UCLA Department of Radiology, Department of Radiation Oncology, University of California, Los Angeles, UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Endobronchial Valves (EBV) are one of the few treatment options for patients with moderate to severe emphysema. Eligibility is typically assessed from CT image data analysis including Emphyse...
Authors: Ulrike Dydak, Chia-Tien Hsu, Chang Geun Lee, Cora Mizimakoski, Humberto Monsivais, Jae Hong Park
Affiliation: Purdue University
Abstract Preview: Purpose: Overexposure to manganese (Mn) from inhaling welding fumes can lead to cognitive and motor deficits. We developed a whole-brain Mn-mapping approach to detect subtle but significant increases ...
Authors: Jaydev K. Dave, Krzysztof R Gorny, Chunming Gu, Nicholas J. Hangiandreou, Gina K. Hesley, Myung-Ho In, Zaiyang Long, Aiming Lu, Christin A. TiegsHeiden
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
MR-guided focused ultrasound (MRgFUS) enables precise tumor ablation with real-time MR-thermometry guidance. Our practice is exploring the potential use of Feraheme (Ferumoxytol), a superp...
Authors: CheukKai Becket Hui, Goldie M. Klein, Yildirim D. Mutaf, Amir Pourmoghaddas
Affiliation: UC Health, Kaiser Permanente
Abstract Preview: Purpose:
In this study, we investigated the effect of SGRT (Align-RT) implementation on patient setup accuracy for DIBH breast radiotherapy treatments.
Methods:
We extracted vertical post-ima...
Authors: Mahya Ahmadzadeh, Nagarajan Kandasamy, Keyur Shah, Gregory C. Sharp, Santhosh Vadivel, John MacLaren Walsh
Affiliation: Electrical and Computer Engineering Department, Massachusetts General Hospital, Emory University, Drexel University
Abstract Preview: Purpose: In image-guided radiotherapy (IGRT), cone beam CTs (CBCTs) suffer from distortions that degrade registration with planning CTs. While CycleGANs can generate synthetic CTs (sCTs) from CBCTs, e...
Authors: Seungryong Cho, Donghyeok Choi, Joonil Hwang, Byung-Hee Kang, Jin Sung Kim, Eungman Lee, Younghee Park
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, KAIST, Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine, Ewha Womans University of Medicine
Abstract Preview: Purpose: Radiation therapy (RT) is critical for cancer treatment, but changes in tumor size and shape during therapy challenge precise dose delivery. Adaptive radiation therapy (ART) addresses these v...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...
Authors: María Fernández, Inés Flores, Nuria Montero, Manuel Ruiz, Francisco San Miguel
Affiliation: Hospital Central de la Defensa 'Gómez Ulla', Hospital Central de la Defensa "Gomez Ulla", CSVE, Hospital Central de la Defensa 'Gómez Ulla', CSVE
Abstract Preview: Purpose:
During external radiotherapy treatments in the prostate, there can be PTV movements between fractions and during each treatment fraction. In a typical prostate treatment in our institution...
Authors: Wendy Siman, Wei Zhou
Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-µm tungsten wire was imaged at ...
Authors: Zong Fan, Fan Lam, Hua Li, Rita Huan-Ting Peng, Yuan Yang
Affiliation: University of Illinois at Urbana Champaign, University of Illinois at Urbana-Champaign, Washington University School of Medicine, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Accurate lesion segmentation in MRI is critical for early diagnosis, treatment planning, and monitoring disease progression in various neurological disorders. Cross-site MRI data can alleviat...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: Jue Jiang, Aneesh Rangnekar, Shiqin Tan, Harini Veeraraghavan
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Weill Cornell Graduate School of Medical Sciences
Abstract Preview: Purpose: Clinicians often use information from FDG-PET and CT to interpret and delineate gross tumor (GTVp) and nodal (GTVn) volumes for radiotherapy planning in head and neck (HN) cancer patients. He...
Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu
Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...
Authors: Olubunmi Odunola Aregbe, Clara Ferreira, Margaret Reynolds, David A. Sterling
Affiliation: University of Minnesota, University of Minnesota Physicians, Department of Radiation Oncology, University of Minnesota, Minneapolis
Abstract Preview: Purpose: Current best practices recommend daily imaging and planning for Tandem and Ring (T&R) HDR patient plans. Accurate target delineation is a critical, yet time consuming step in this process. Th...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...
Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang
Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center
Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Gantry motion and patient breathing during a breast cone beam CT (bCBCT) scan is one of the major challenges for microcalcification (μCalcs) detection. By deploying a large number of individu...
Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu
Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center
Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...
Authors: Harald Keller, Iymad Mansour, Jeff D. Winter
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...
Authors: John T Barrett, Chulhaeng Huh, Farshad Mostafaei, Michelle Rocque, Austin Sanders
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University, Georgia Radiation Therapy Center, Wellstar-MCG Health
Abstract Preview: Purpose: This study involved the use of Accuray’s TPS (Precision) and RayStation TPS for planning TBI treatments. TBI was delivered using Accuray’s Radixact machine, and dose calculation algorithm, do...
Authors: Amanda J. Deisher, Andrew YK Foong, Witold Matysiak, Jing Qian, Xueyan Tang, Erik J. Tryggestad, Mi Zhou
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Phase gating is commonly employed to mitigate the impact of tumor motion in radiotherapy. Due to the machine-specific time delay between triggering and radiation delivery, the triggering sign...
Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou
Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...
Authors: Hao Gao, Jiayue Han, Wangyao Li, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Proton therapy leverages Bragg-peak-based dose delivery to achieve ultra-high-dose-rate FLASH with patient-specific range modulators (PSRM). Current proton FLASH (pFLASH) planning typically i...
Authors: Xiangli Cui, Zilei Fu, Man Hu, Wanli Huo, Xiaoqing Wu, Jianguang Zhang, Yingying Zhang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
Using Stable Diffusion to generate images of the knee in different disease states can enrich the medical imaging database and inject new vitality into the field of medical imaging analysis...
Authors: Justus Adamson, John Ginn, Yongbok Kim, Ke Lu, Trey Mullikin, Xiwen Shu, Chunhao Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose:
To develop a knowledge-based deep model for synthetic CT (sCT) generation from a single MR volume in frameless radiosurgery (SRS), eliminating the need for CT simulation prior to the SRS d...
Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi
Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital
Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...
Authors: Yan Dai, Jie Deng, Christopher Kabat, Weiguo Lu, Ying Zhang, Hengrui Zhao
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
MRI-guided adaptive radiotherapy (MRgART) using MR-LINAC systems offers significant advantages for liver cancer, enabling superior tumor delineation and online plan adaptation. However, ma...
Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...
Authors: Ben Piacitelli, Celeste Winters
Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University
Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...
Authors: Nadège Anizan, Jean-Noël Badel, Thomas Baudier, David Broggio, Désirée Deandreis, Ludovic Ferrer, Didier Franck, Camilo Garcia, Jean Gasteuil, Anne-Laure Giraudet, Olivier Humbert, Laetitia Imbert, Malick Koulibaly, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard, Caroline Rousseau, Guido Rovera, David Sarrut, Paul Schwartz, Nicolas Varmenot
Affiliation: Institut de Cancérologie de l’Ouest, Service de Médecine Nucléaire, Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, CHRU de Nancy Brabois, Service de Médecine Nucléaire, Centre de lutte contre le cancer Léon Bérard, Université de Lyon, Centre Antoine Lacassagne, Service de Médecine Nucléaire, Université Nice Côte d’Azur, Centre Antoine Lacassagne, Service de Médecine Nucléaire, Gustave Roussy, Service de Médecine Nucléaire, Institut de Cancérologie de l’Ouest, Service de Physique Médicale, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS, CREATIS CNRS UMR 5220; INSERM U 1044; Université de Lyon; INSA‑Lyon, CREATIS CNRS UMR 5220; INSERM U 1044; Université de Lyon; INSA‑Lyon; Centre de lutte contre le cancer Léon Bérard, Institut Bergonié, Service de Médecine Nucléaire
Abstract Preview: Purpose: The main objective of the Lu-PSMA-Dose study, sponsored by ASNR, is to estimate retrospectively the individual absorbed dose delivered to patients treated with 177Lu-PSMA for metastatic castr...
Authors: Yasaman Anbari, Srinivas Cheenu Kappadath, Benjamin P. Lopez
Affiliation: University of Houston, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To improve lung dosimetry for 90Y-radioembolization planning, CT-based techniques have been proposed for patient-specific lung mass estimation instead of assuming nominal 1 kg lung masses. He...
Authors: Min Cheol Han, Jin Sung Kim, Seok Ho Lee, Gahee Son, Yongdo Yun
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: This study aims to develop the MC-DOLCE, a Monte Carlo (MC)-based system capable of calculating physical and biological dose distributions, as well as linear energy transfer (LET) distributio...
Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying
Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital
Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...
Authors: Alanah M. Bergman, Marc W Deyell, Tania Karan, Jakob Marshall, Justin Poon, Devin Schellenberg, Steven Thomas, Richard Thompson
Affiliation: University of British Columbia, University of Alberta, BC Cancer
Abstract Preview: Purpose: A conservative approach to account for random errors due to intra-fraction cardiac and respiratory motion during cardiac radioablation (CR) is to define a margin equal to the amplitude of car...
Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Metallic implants can significantly distort sinograms, leading to severe artifacts in computed tomography (CT) reconstructions. Reconstructing CT images containing metal is fundamentally an i...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Iowa, Iowa Health Care
Abstract Preview: Purpose:
To perform end-to-end treatment planning and delivery verification of energy-specific collimated treatments optimized to achieve the maximum obtainable high-dose conformity using the dynam...
Authors: Rachel B. Ger, Xun Jia, Youfang Lai, Todd R. McNutt, Xingyi Zhao
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Radiotherapy (RT) plays an essential role for head and neck (HN) cancer treatment but often results in xerostomia due to salivary gland damage. It is important to mechanistically model the ra...
Authors: Andrew R. Godley, Steve B. Jiang, Mu-Han Lin, Austen Matthew Maniscalco, Dan Nguyen, Yang Kyun Park
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Preparing DICOM datasets for research and education is challenging due to the complexity of the format and the necessity for patient-specific handling. Existing workflows demand substantia...
Authors: Ziqi Gao, Lei Xing, Siqi Ye, S. Kevin Zhou
Affiliation: Department of Radiation Oncology, Stanford University, University of Science and Technology of China (USTC)
Abstract Preview: Purpose: To address the challenge of high memory usage in volumetric cone-beam CT (CBCT) imaging, we propose a method that combines joint reconstruction and super-resolution for sparsely sampled CBCT ...
Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich
Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...
Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...
Authors: Indra J. Das, Ahtesham U. Khan, Andrew J. White, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: During intensity modulated radiotherapy (IMRT) planning, low MU segments (< 3 MU) are commonly avoided due to documented dosimetric nonlinearity and poor reproducibility. This work aims to ex...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Christopher Ackerman, Chang Chang, Yan-Cheng Huang, Robert Kaderka, Che Lin, Hsin-Chih Lo, Iain MacEwan, Yi-Chin Tu, James Urbanic
Affiliation: University of California San DIego, Taiwan AI Labs, National Taiwan University, California Protons Cancer Therapy Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: To investigate the performance of an existing AI beam angle prediction model on external patient datasets for liver proton treatments. The AI model was trained on datasets exclusively from on...
Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati
Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...
Authors: Smith Apisarnthanarax, Stephen R. Bowen, Sunan Cui, Jie Fu, Clemens Grassberger, Yulun He, Yejin Kim, Matthew J. Nyflot, Sharon Pai
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington, University of Washington and Fred Hutchinson Cancer Center
Abstract Preview: Purpose: 99mTc-sulfur colloid SPECT imaging enables quantitative assessment of voxel-wise liver function in patients with hepatocellular carcinoma (HCC). Accurately predicting post-radiotherapy (RT) l...
Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas
Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...
Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...
Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas
Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco
Abstract Preview: Purpose: Hospital readmission prediction models often rely on structured Electronic Health Record (EHR) data, overlooking critical insights from unstructured clinical notes. This study presents a mult...
Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University
Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...
Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik Peruško, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, Maíra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo Castañeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum
Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. 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Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. 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Abstract Preview: N/A...
Authors: Hassan Bagher-Ebadian, Ahmed I Ghanem, Joshua P. Kim, Chengyin Li, Rafi Ibn Sultan, Kundan S Thind, Dongxiao Zhu
Affiliation: Wayne State University, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Accurate segmentation of the Left Anterior Descending (LAD) artery in free-breathing 3D treatment planning CT is crucial for radiotherapy but remains challenging due to its small size, comple...
Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang
Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...
Authors: Samuel L. Brady, Shruti Hegde, Alexander Knapp, Usman Mahmood, Joseph G. Meier, Elanchezhian Somasundaram, Zachary Taylor
Affiliation: Cincinnati Children's Hospital Medical Ctr, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Cincinnati Children's Hospital Medical Center, Cincinnati Childrens Hospital Med Ctr
Abstract Preview: Purpose:
To assess how two benchmark multi-organ CT segmentation models respond to varying image noise levels.
Methods:
This study utilized the pediatric CT dataset from The Cancer Imaging Ar...
Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever
Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center
Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...
Authors: Mavlonbek Khomidov, Jong-Ha Lee
Affiliation: Department of Biomedical Engineering, Keimyung University, Department of Computer Engineering, Keimyung University
Abstract Preview: Purpose: In this research, we aim to estimate blood pressure using remote photoplethysmography (rPPG) signal extracted from facial video. This method provides non-invasive and contactless, continuous ...
Authors: Wenchao Cao, Yingxuan Chen, Haisong Liu, Richard A. Popple, Wenyin Shi, Rodney J. Sullivan, Wentao Wang, Lydia J. Wilson, Zhenghao Xiao
Affiliation: Thomas Jefferson University, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: Objectively evaluating brain sparing as a plan-quality indicator for patients receiving stereotactic radiosurgery (SRS) to multiple metastases (multi-met) is complicated by variability in tar...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Mingyang Han, Jia Jing, Chongming Li, Hui Lin, Zhenyu Xiong
Affiliation: School of Physics, Hefei University of Technology, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: To enrich the teaching case library of Computational Physics course, one of the basic courses in undergraduates majoring in physics. It is an excellent application case of Medical Physics for...
Authors: Colton Baley, Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz
Affiliation: UT Health San Antonio, Texas Oncology, University of Texas HSC San Antonio
Abstract Preview: Purpose: To evaluate the accuracy of off-axis winston lutz (WLT) for linac based stereotactic radiosurgery (SRS) treatments using in-house phantom.
Methods: Traditional WLT that uses cone and s...
Authors: Shahed Badiyan, Girish Bal, Thomas I. Banks, Bin Cai, Tu Dan, Aurelie Garant, Andrew R. Godley, Steve Jiang, Orhan Oz, Arnold Pompos, Rameshwar Prasad, Chenyang Shen, David Sher, Robert Timmerman, Kenneth Westover
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) is a novel FDA-cleared technology for treating lung and bone tumors based on 18F-FDG PET uptake. This study summarizes the first-year experience treating 29...
Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li, Junzhong Xu
Affiliation: Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiology, Vanderbilt University Medical Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cell size is a vital parameter in evaluating the tumor microenvironment, including cell apoptosis and radiotherapy(RT)-induced immune cell infiltration. The IMPULSED(Imaging Microstructural P...
Authors: Chih-Wei Chang, Junbo Peng, Richard L.J. Qiu, Justin Roper, Xiangyang Tang, Tonghe Wang, Huiqiao Xie, Xiaofeng Yang, David Yu
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Emory Univ, Emory University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Limited-angle dual-energy (DE) cone-beam CT (CBCT) is considered a promising solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, ...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Multi-layer flat-panel imagers can improve for clinical image-guided radiotherapy applications, including the enhanced visualization of soft tissue and a reduction in image artifacts. Each im...
Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske
Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago
Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...
Authors: Chia-Lung Chien, Wen C. Hsi, Faraz Kalantari, Pouya Sabouri, Man Yam
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
Reducing treatment delivery time is critical to improving patient throughput and minimizing the risk of intrafraction motion, which can compromise treatment accuracy. This study identifies...
Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...
Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna
Affiliation: UNAM, Medica Sur
Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...
Authors: Wouter Crijns, Frederik Maes, Loes Vandenbroucke, Liesbeth Vandewinckele
Affiliation: Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven; Department of Radiation Oncology, UZ Leuven, Department ESAT/PSI, KU Leuven; Medical Imaging Research Center, UZ Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven
Abstract Preview: Purpose: To explore intentional deep overfit learning (IDOL) to exploit the initial treatment plan to predict an adaptive radiotherapy plan.
Methods: A conditional generative adversarial network is...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: Loren Bell, Charles S Cathcart, Brett William Eckroate, Harold Y Hu, Joshua Kilian-Meneghin, Ke Nie, Fredrick Warburton, Zhenyu Xiong, Keying (Karen) Xu, Ning J. Yue, Yin Zhang, Lili Zhou
Affiliation: RWJBarnabas Health, Basis Scottsdale, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: This study compares the dosimetric impact of multiple metal artifact reduction (MAR) algorithms from different CT simulator vendors using an anthropomorphic head phantom for head-and-neck (H/...
Authors: Chao Guo, Xinhua Li, Michael F. McNitt-Gray, Di Zhang, Yifang (Jimmy) Zhou
Affiliation: UCLA, David Geffen School of Medicine at UCLA, Cedars-Sinai Medical Center
Abstract Preview: Purpose: The objective was to quantify the liver fat volume fraction (FVF) with virtual monochromatic imaging (VMI) using photon-counting CT (PCCT) and dual energy CT (DECT).
Methods: A custom desi...
Authors: Carina Gassner, Guyue Hu, Thomas Kröncke, Christopher Kurz, Guillaume Landry, Katharina Niepel, Katia Parodi, Franka Risch, Florian Schwarz
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Department of Diagnostic and Interventional Radiology, University Hospital Augsburg, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich)
Abstract Preview: Purpose: To evaluate the performance of a clinical photon-counting CT (PCCT) scanner in terms of proton relative stopping power (RSP) estimation using PCCT data and to compare the impact of different ...
Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...
Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou
Affiliation: University of Nebraska Medical Center
Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...
Authors: John Ginn, Zhuoyun Huang, Yongbok Kim, Ke Lu, Chunhao Wang, Yibo Xie, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose: This study aims to develop and validate a machine learning model for predicting V60%, a critical dosimetric metric in LINAC-based Single-Isocenter-Multiple-Targets (SIMT) stereotactic radiosu...
Authors: Hua-Chieh Shao, Guoping Xu, You Zhang, Tingliang Zhuang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Advancements in onboard X-ray hardware allow high-quality CBCT imaging with a short scan time (~6s for Varian HyperSight), enabling CBCT-based dose calculation and treatment planning. Howe...
Authors: Ahmad K. Al-Basheer, Andrew Clarke Grice, Kelly E. Hosier, Mark Logsdon, Evan A. Silverstein, Chris Tunnicliff, Chuan Wu
Affiliation: Sutter Medical Foundation, Sutter Health
Abstract Preview: Purpose: For Prostate SBRT Boost treatments, determine whether a uniform 2mm CTV to PTV margin is sufficient to give 95% dose coverage to the CTV in 90% of patients via a modified Van Herk Margin Form...
Authors: Jeremy S. Bredfeldt, Daniel W. Cail, Maria A. Czerminska, Cindy I. Hancox, David Hu, Benjamin Karasko, Claire Keun Sun Park
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Brigham and Women's Hospital, Brigham and Women’s Hospital and Dana Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: To develop a robust clinical protocol for in vivo dosimetry in radiotherapy using the myOSLchip Optically Stimulated Luminescent Dosimeter (OSLD) system by performing characterization and eva...
Authors: Ali Ammar, Quan Chen, Jingwei Duan, Yi Rong, Nathan Y. Yu, Libing Zhu
Affiliation: Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Clinical performance of deep learning-based auto-segmentation (DLAS) can degrade over time due to AI “aging” from unseen data input compared to the initial model training data. This study aim...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose: Gradient-based optimization is the standard approach for IMRT fluence map optimization (FMO). Recently, a machine learning (ML)-assisted framework using a one-layer neural network was propose...
Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Maria F. Chan, Yabo Fu, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Lee, Tianfang Li, Xiang Li, Jean M. Moran
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Iodine maps derived from Dual-Energy CT (DECT) provide critical biological information for radiotherapy treatment planning, but clinical iodine maps often mistakenly include bones due to insu...
Authors: David L. Barbee, David Byun, Ting Chen, Paulina E. Galavis, Siming Lu, Sarah Rosemary Morris, Hesheng Wang, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose: MR-Linac enables dose escalation in prostate SBRT on accurately defined dominant intra-prostate lesion (DIL) on daily MR images. This study aims to evaluate inter-fraction changes in the radi...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger
Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...
Authors: Petr Bruza, David J. Gladstone, Lesley A Jarvis, Austin Sloop, Kevin J. Willy, Rongxiao Zhang
Affiliation: Thayer School of Engineering, Dartmouth College, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose:
Active beam monitoring and output-gated dosimetry are essential systems for safe and accurate radiation delivery. UHDR irradiators such as the Mobetron rely on pre-programmed regimes and t...
Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao
Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.
Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...
Authors: Shreyas Anil, Jason Chan, Arushi Gulati, Yannet Interian, Hui Lin, Benedict Neo, Andrea Park, Bhumika Srinivas
Affiliation: Department of Otolaryngology Head and Neck Surgery, University of California San Francisco, Department of Data Science, University of San Francisco, Department of Radiation Oncology, University of California San Francisco, University of San Francisco
Abstract Preview: Purpose: As Large Language Models (LLMs) continue to evolve, their ability to analyze Electronic Health Record (EHR) notes for clinical decision support expands. Chain of Thought (COT) reasoning, an e...
Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...
Authors: Matthew Case, Richard Castillo, Sunil Dutta, Edgar Gelover, Katja M. Langen, Alexander Stanforth, Mingyao Zhu
Affiliation: Emory University
Abstract Preview: Purpose: To evaluate the application of LETd and track-end (TE) objective functions during the optimization of breast proton therapy plans to decrease the risk of lung toxicity and rib fractures.
M...
Authors: Weixing Cai, Laura I. Cervino, Qiyong Fan, Yabo Fu, Tianfang Li, Xiang Li, Jean M. Moran, Hai Pham, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: AAPM Task Group Report 273 emphasizes the importance of rigorous validation to ensure the generalizability and robustness of machine learning-based clinical tools before their implementation ...
Authors: Sandeep Panwar Jogi, Nancy Lee, Ricardo Otazo, Ramesh Paudyal, Qi Peng, Akash Shah, Amita Shukla-Dave, Can Wu
Affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiology, Albert Einstein College of Medicine and Montefiore Medical Center
Abstract Preview: Purpose: Quantitative T1ρ imaging provides enhanced tissue characterization beyond standard T1 and T2 parameters, potentially supporting early-stage longitudinal monitoring of head and neck cancer. Th...
Authors: Mu-Han Lin
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: N/A...
Authors: Salim Balik, Eric Chang, Kristine Garcia, Andrew Islas, Lijun Ma, Zhilei Liu Shen, Elizabeth Zhang-Velten
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: NRG protocols recommend simulating and treating head and neck (HN) cancer patients in a supine position for optimal setup reproducibility. However, certain patients cannot tolerate the supine...
Authors: Xiangli Cui, Chi Han, Man Hu, Wanli Huo, Xunan Wang, Jianguang Zhang, Yingying Zhang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, China Jiliang University, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, China Jiliang University,
Abstract Preview: Purpose:
Medical image generation has broad application prospects in deep learning, but the model training effect is often limited due to the lack of real image data. This study aims to explore the...
Authors: Jiali Gong, Yi Guo, Chi Han, Wanli Huo, Hongdong Liu, Zhao Peng, Yaping Qi, Zhaojuan Zhang
Affiliation: Department of Radiotherapy, cancer center, The First Affiliated Hospital of Fujian Medical University, Department of Oncology, Xiangya Hospital, Central South University, State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, China Jiliang University, Division of lonizing Radiation Metrology, National Institute of Metrology, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University
Abstract Preview: Purpose: To address overfitting from limited training data in multi-organ segmentation, an efficient transfer learning framework is proposed. It reduces reliance on training samples, enabling a single...
Authors: Shixiong Huang, Daming Li
Affiliation: The Affiliated Nanhua Hospital, University of South China, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital
Abstract Preview: Purpose: To assess the feasibility of using target current pulse signals to evaluate the output dose of medical standing wave electronic linear accelerators.
Methods: The Target I signal of the acc...
Authors: Marian Axente, Mandeep Kaur
Affiliation: Emory University
Abstract Preview: Purpose: To validate a low-cost optical imaging system for respiratory monitoring by comparing its accuracy and feasibility against the clinical gold standard in human subjects.
Methods: Following ...
Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang
Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill
Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...
Authors: Sean L. Berry, Weixing Cai, Laura I. Cervino, Yusuf Emre Erdi, Yabo Fu, Yiming Gao, Daphna Gelblum, Wendy B. Harris, Xiuxiu He, Tianfang Li, Xiang Li, Seng Boh Gary Lim, Jean M. Moran, Mitchell Yu, Hao Zhang
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Gated CBCT (gCBCT) is commonly employed for respiratory gating lung cancer patients to ensure precise patient setup. However, the scan is time-consuming on C-arm linear accelerators (LINAC) d...
Authors: Angela Gearhardt, Stephen F. Kry, Christopher Ryan Peeler, Julianne M. Pollard-Larkin
Affiliation: The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences; The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: A growing number of radiation therapy (RT) patients have cardiovascular implantable electronic devices (CIEDs). Patients with CIEDs must be carefully managed because the devices are susceptib...
Authors: Hilary Louisa Byrne, Paul J. Keall, John Kipritidis, Jeremy Lim
Affiliation: Northern Sydney Cancer Centre, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney
Abstract Preview: Purpose:
Non-contrast CT ventilation imaging (CTVI) has been developed as a cost-effective and accessible alternative to PET/SPECT V/Q imaging for visualizing lung function. However, the sensitivit...
Authors: Matthew Brown, Yushi Chang, Jinhyuk Choi, William Silva Mendes, Lei Ren, Aman Sangal, William Paul Segars, Phuoc Tran, Hualiang Zhong
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Digital phantoms like XCAT are essential for imaging and treatment optimization in radiology and radiation oncology. However, the lack of realistic textures (HU distribution) in XCAT limits i...
Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...
Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu
Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...
Authors: Rajeev K. Badkul, Ronald C Chen, Ying Hou, Harold Li, Chaoqiong Ma, Jufri Setianegara
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose:
Postimplant urinary toxicity is common in prostate low-dose-rate (LDR) brachytherapy. We developed a machine learning (ML) model to explore the correlation between spatial dose distributio...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Laura I. Cervino, Sharif Elguindi, Yu-Chi Hu, Licheng Kuo, Xiaoning Liu, Jennifer Ma, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Radiation Oncology, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
Quad-shot radiotherapy (QSRT) is an emerging paradigm in palliative cancer treatment. This study aimed to streamline the QSRT workflow using automation to improve efficiency while maintain...
Authors: Michael Baine, Charles Enke, Yang Lei, Yu Lei, Ruirui Liu, Su-Min Zhou
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Radiation Oncology, University of Nebraska Medical Center
Abstract Preview: Purpose: This study presents a framework for generating synthetic CT images using a Cycle Diffusion model, which can be utilized to enhance needle conspicuity in ultrasound-guided prostate HDR brachyt...
Authors: Hoyeon Lee
Affiliation: University of Hong Kong
Abstract Preview: Purpose: Deep-learning approaches are widely investigated for Cone-Beam CT (CBCT) scatter correction to improve the quality of the linear-accelerator mounted CBCT. This study aims to optimize the deep...
Authors: Isaac J. Bailey, Lindsay S. DeWeese, Anna M. Mench, Celeste Winters
Affiliation: Oregon Health & Science University, Department of Diagnostic Radiology, Oregon Health & Science University
Abstract Preview: Purpose: The emergence and recent FDA approval of several new radiopharmaceutical therapies have increased demand for physicists to provide specialized support. However, these topics are not yet inclu...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...
Authors: Joana Antunes, Scott James Bright, David B. Flint, Mojtaba Hoseini-Ghahfarokhi, Mandira Manandhar, Poliana Marinello, Gabriel O. Sawakuchi, Tingshi Su
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Laboratory of Instrumentation and Experimental Particle Physics; Faculty of Science of University of Lisbon, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, MD Anderson Cancer Center
Abstract Preview: Purpose: To study the accuracy of relative biological effectiveness (RBE) models to predict the RBE of a comprehensive panel of pancreatic cancer cell lines.
Methods: Clonogenic cell survival w...
Authors: Wen C. Hsi, Tae Kyu Lee, Biniam Yo Tesfamicael
Affiliation: Allina Health, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Oklahoma Proton Center
Abstract Preview: Purpose: When minimal dose-variations induced by inter-fractional anatomical-changes and positioning-deviation were found for having limited impact on clinic-outcomes of oropharyngeal head-and-neck (H...
Authors: Xiangli Cui, Wanli Huo, Jie Li, Lingling Liu, Tao Ma, Yuanyuan Wang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Ion Medical Center, Hefei Cancer Hospital, Chinese Academy of Sciences, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University
Abstract Preview: Purpose: In practice, treatment planning systems (TPS) of proton therapy require a CT calibration curve, which relates Hounsfield units (HU) to relative stopping power (RSP). Single-energy CT as a sta...
Authors: Matthew S Brown, John M. Hoffman, William Hsu, Grace Hyun Kim, Michael F. McNitt-Gray, Spencer Harrison Welland, Anil Yadav
Affiliation: Department of Bioengineering, UCLA, David Geffen School of Medicine at UCLA, UCLA Department of Radiology
Abstract Preview: Purpose: Non-contrast CT (NCCT) is frequently used in initial evaluation of suspected stroke to rule out intracerebral hemorrhage. Quantitative scoring systems like the Alberta Stroke Program Early CT...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...
Authors: Jiayun Chen, Shengqi Chen, Junchao Li, Fei Liu, Jianan Wu
Affiliation: Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center, Tongji Medical College, Huazhong University of Science & Technology, School of Electronic Engineering, Beijing University of Posts and Telecommunications, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To assess if 3D Vane MRI can accurately depict the motion of the target volume and OARs.
Methods: This retrospective study included 54 liver cancer patients who underwent both 3D Vane MRI ...
Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Conventional computed tomography (CT) measures the collective attenuation of primary photon fluence and then reconstructs the 3D images without using the timing information of individual phot...
Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven
Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University
Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...
Authors: Grant Gibbard, Chunhui Han, An Liu
Affiliation: RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To evaluate the efficacy of a new approach to streamline treatment planning for biology-guided radiotherapy (BgRT) of fluorodeoxyglucose (FDG)-avid bony lesions on a BgRT machine with real-ti...
Authors: Jing Qian, Brandon Reber, David M. Routman, Satomi Shiraishi
Affiliation: Mayo Clinic
Abstract Preview: Purpose: The dose distribution in proton radiotherapy (PRT) is characterized by sharp gradients, posing a challenge for machine learning-based dose prediction. While denoising with diffusion processes...
Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.
Methods: A commercial rotational table (CDR Equilibrium®) is r...
Authors: John T Barrett, Dan Heo, Chulhaeng Huh, Farshad Mostafaei
Affiliation: Department of Radiation Oncology, Medical College of Georgia, Augusta University, Department of Radiation Oncology, Augusta University
Abstract Preview: Purpose: This study aimed to compare the tumor control probability (TCP) of radiation therapy (RT) and magnetic hyperthermia combined with RT (MHRT) in the human prostate cancer cells based on radiobi...
Authors: Lu Jiang, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Conventional radiotherapy treatment planning is guided by a set of generic objectives that are unspecific to patient anatomy. Treatment planning thus heavily relies on the planner’s experi...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Active breath-hold techniques effectively mitigate respiratory motion but poses challenges for patients who are unable to tolerate the procedure. Conventional planning relies on multiple ener...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Renxin Chu, Jelena Mihailovic, Kai Yang, Lifeng Yu, Da Zhang
Affiliation: Massachusetts General Hospital, Mayo Clinic, Boston Children's Hospital, UVA Health University Hospital, University of Missouri Health Care
Abstract Preview: Purpose:
A frequently used method to estimate effective dose (ED) in CT is by multiplying the dose length product (DLP) by a conversion factor, known as k-factor. The k-factor in this method is sus...
Authors: Yunxiang Li, Weiguo Lu, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Curating high-quality, labeled data for medical image segmentation can be challenging and costly, considering the existence of various image domains with differing modalities/protocols. Cr...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...
Authors: Roger Eric Goldman, Adrianna Imani Johnson Carter, Talia Marx, Brahim Mehadji, Emilie Roncali, Catherine T. Vu
Affiliation: UC Davis, Department of Radiology, UC Davis Health
Abstract Preview: Purpose:
Accurate estimation of the Lung Shunt Fraction (LSF) is critical for yttrium-90 (90Y) radioembolization treatment planning to minimize risks of excessive lung irradiation due to arterio-ve...
Authors: Ibtisam Almajnooni, Siyong Kim, Nathaniel Miller, Elisabeth Weiss, Lulin Yuan
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: Radiation-induced esophagitis (RE) is a common concern in lung cancer IMRT. Recent studies have indicated that the risk of radiation side effects varies greatly with patients’ baseline clinic...
Authors: Jie Hu, Nan Li, Chuanbin Xie, Shouping Xu, Xinlei Xu, Gaolong Zhang, Zhilei Zhang
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, the First Medical Center of the People's Liberation Army General Hospital, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, Peopleʼs Republic of China, Department of Radiation Oncology, School of Physics, Beihang University, Beijing, 102206, Peopleʼs Republic of China
Abstract Preview: Purpose: This study aims to synthesize CT images for MRI-only radiation therapy using a deep learning approach that integrates information from the T1- and T2-weighted MRI sequence.
Methods: 97 hea...
Authors: Jameson T. Baker, Sean T Grace, Cindy Pham, Michael A. Trager
Affiliation: Northwell
Abstract Preview: Purpose:
In VMAT planning, increasing complexity in MLC motion and modulation may improve dose distributions and OAR sparing while maintaining PTV coverage. However, increasing complexity can creat...
Authors: Casey E. Bojechko, Tricia Chinnery, Grace Gwe-Ya Kim, Xenia Ray
Affiliation: University of California San Diego
Abstract Preview: Purpose: To evaluate the use of a calibration curve generated from the CT simulator for direct dose calculation on cone beam computed tomography (CBCT) images taken with the on-board imaging system. T...
Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison
Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...
Authors: Ozgur Ates, Chin-Cheng Chen, Chia-Ho Hua, Matthew J. Krasin, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: To validate the use of synthetic CTs generated from CBCT images for online monitoring, ensuring accurate and reliable daily plan quality assessments in adaptive proton therapy (APT).
Metho...
Authors: Min Cheol Han, Soorim Han, Chan Hyeong Kim, Jin Sung Kim, Seok-Ho Lee, Gahee Son, Yongdo Yun
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Hanyang University, Department of Integrative Medicine, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The stoichiometric calibration method proposed by Kanematsu et al. (2016) has been widely adopted for CT number to stopping-power ratio (SPR) conversion in carbon-ion radiotherapy. With the r...
Authors: Dong Wook Kim, Jin Sung Kim, Dongho Lee, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)
Abstract Preview: Purpose:
This study aims to analyze the characteristics of a novel detector based on a dielectric layer (Vieworks Co., Korea), which demonstrates high tolerance to high radiation doses and light tr...
Authors: Duncan Henry Bohannon, Pretesh Patel, Sibo Tian, Yinan Wang, Xiaofeng Yang, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
4D robust optimization, incorporating additional images (e.g., maximum inhale/exhale phases), is commonly used to account for target motion in proton treatment planning. However, the incre...
Authors: Mark Anastasio, Zong Fan, Hua Li, Changjie Lu, Lulu Sun, Xiaowei Wang, Zhimin Wang, Michael Wu
Affiliation: University of Illinois at Urbana-Champaign, University of Illinois at Chicago, Washington University School of Medicine, University of Illinois Urbana-Champaign, Washington University in St. Louis, University Laboratory High School
Abstract Preview: Purpose: Histological whole slide images (WSIs) are vital in clinical diagnosis. Although deep learning (DL) methods have achieved great success in this task, they often lack interpretability. Traditi...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...
Authors: Sarah Huo, David Zander, Wei Zhou
Affiliation: Cherry Creek High School, University of Colorado Anschutz Medical Campus, University of Colorado Anschutz Medical Campus, School of Medicine
Abstract Preview: Purpose:
Ring artifact is commonly seen in CT, and it is usually caused by detector element failure or miscalibration. Although many ring artifacts are apparent and easy to recognize, those origina...
Authors: Kristy K. Brock, Austin Castelo, Yulun He, Zhongxing Liao, Rebecca Lim, Radhe Mohan, Caleb O'Connor, Tien T Tang, Uwe Titt
Affiliation: University of Washington, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Conformal dose distributions in proton radiotherapy promise to reduce normal tissue toxicity such as radiation-induced pneumonitis, but this has not been fully realized in clinical trials. To...
Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...