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Results for "Ming Su": 162 found

60RPM Rotational Winston Lutz Test to Characterize Operational MV-Kv Offset on Reflexion X1 System

Authors: Huixiao Chen, Ethan Hartowicz, Lichung Ku, Tim Perez, Ray Yang

Affiliation: Salem Health, RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To characterize MV-kV isocenter offset on a novel ring gantry radiotherapy system where the Linac, PET, kV-CT, and MV imaging subsystems rotate together at native operating speed of 60RPM.

A 2D Discrete Ionization Chamber Array for Proton Pencil Beam Scanning Flash Dosimetry

Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou

Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica

Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...

A Comparative Analysis of Hand Calculations and Macro Monte Carlo Simulations for Electron Beam Dosimetry

Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr

Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado

Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...

A Dual Energy CT-Guided Intelligent Radiation Therapy Platform

Authors: Jiayi Chen, Manju Liu, Ning Wen, Haoran Zhang, Yibin Zhang

Affiliation: Department of Radiation Oncology, Ruijin Hospital, Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Duke Kunshan University, Department of Radiation Oncology,Ruijin Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: This study introduces a novel Dual Energy CT (DECT)-Guided Intelligent Radiation Therapy (DEIT) platform designed to streamline and optimize the radiotherapy process. The DEIT system combines...

A GPU Accelerated Monte Carlo Dose Engine for Small Animal Proton Radiotherapy

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Zihao Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Cheng Zheng

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose:
Proton radiotherapy in preclinical small animals requires specific dose engine due to its low energy and small irradiation volume. This study is to develop a GPU-based Monte Carlo dose eng...

A Monte Carlo-Based Secondary Dose Verification Tool for Treatment Plans of Robotic Radiosurgery System

Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...

A Multi-Criteria Optimization Method Based on Reinforcement Learning and Adaptive Boosting in Radiation Therapy

Authors: Liqin HU, Tao He, Jing JIA, Pengcheng LONG, Wei Meng, Yang Yuan

Affiliation: SuperAccuracy Science & Technology Co. Ltd.

Abstract Preview: Purpose: A multi-criteria optimization method based on reinforcement learning and adaptive boosting(RLAB MCO) has been developed to enhance radiotherapy plan quality by offering reasonable and effecti...

A Multimodal CAD System for Breast Cancer Detection: Integrating MRI, DBT, and Mammography for Dense Breast Challenges

Authors: Si-Wa Chan, Yuan-Yu Lee, Zhi-Ying Li, Jia-Wei Liao, Hui-Yu Cathy Tsai

Affiliation: Department of Radiology, Taichung Veterans General Hospital​, Institute of Nuclear Engineering and Science, National Tsing Hua University

Abstract Preview: Purpose: Dense breast tissue reduces the sensitivity of mammography, posing diagnostic challenges, especially for Asian women with high breast density (up to 50%). Current single-modality techniques o...

A Novel Lattice Technique Based Spot Scanning Proton Arc Therapy Via Spot Sparsity Optimization and LET Optimization

Authors: Zhitao Dai, Riao Dao, Xuanfeng Ding, Qingkun Fan, Yajun Jia, Gang Liu, Gang Peng, Yujia Qian, Hong Quan, Kunyu Yang, Sheng Zhang, Lewei Zhao

Affiliation: Department of Radiation Oncology, Stanford University, Corewellhealth William Beaumont University Hospital, School of Mathematics and Statistics, Wuhan University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital, School of Physics and Technology,Wuhan University, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Abstract Preview: Purpose: Lattice radiation therapy (LRT) is an innovative three-dimensional(3D) implementation type of spatially fractionated radiation therapy (SFRT). This study aims to develop a novel spot-scanning...

A Preliminary Study of Light-Weighted and Flexible Bismuth Nanoparticle-Based Polymer Matrix for Efficient Radiation Shielding

Authors: Ming Su, Yuenan Nancy Wang

Affiliation: Northeastern University, Hartford Healthcare

Abstract Preview: Purpose: High Z elements such as lead are often used to protect critical structures in clinical radiotherapy. Nanoparticles have different properties than bulk materials. We proposed a polymer matrix ...

A Real-Time Framework for Fiducial Tracking and Intrafraction Motion Assessment of Cyberknife in Stereotactic Body Radiation Therapy for Liver Cancer

Authors: Ruiyan Du, Mingzhu Li, Ying Li, Wei Liu, Shihuan Qin, Yiming Ren, Biao Tu, Hui Xu, Lian Zhang, Xiao Zhang, Zengren Zhao

Affiliation: Department of General Surgery, Hebei Key Laboratory of Colorectal Cancer Precision Diagnosis and Treatment, The First Hospital of Hebei Medical University, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Mayo Clinic, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Fiducial tracking is widely used in CyberKnife to dynamically guide the gantry for moving target like liver cancer stereotactic body radiation therapy (SBRT). This study developed a robust fr...

A Two-Layer, Two-Task Prediction Model Based on 3D Imaging and Residual Networks for Mid-Chemoradiation Tumor Response Prediction on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...

A Two-Marker Method for Calculating the Radiological Magnification of the Hip in Standing Pelvic Radiography

Authors: Walaa Abdelfadeel, Reagan Thomas Dugan, Tiffany Kinsey, Cameron Kofler, Zheng Feng Lu, Ingrid S. Reiser, Gregory Stacy, Sara Wallace

Affiliation: University of Chicago Medicine, University of Chicago

Abstract Preview: Purpose: To develop an accurate, vendor-neutral method for estimating geometric magnification at the plane of the hip joint on standing anterior-posterior (AP) radiographs for digital templating of to...

A Vision-Language Model for T1-Contrast Enhanced MRI Generation for Glioma Patients

Authors: Zachary Buchwald, Zach Eidex, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu

Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Gadolinium-based contrast agents (GBCA) are commonly used for patients with gliomas to delineate and characterize the brain tumors using T1-weighted (T1W) MRI. However, there is a rising conc...

AI Auto-Contouring for CT-Based High-Dose-Rate Interstitial Brachytherapy of Cervical Cancer: Implications for Organ-at-Risk (OAR) Contouring and Dosimetric Analysis

Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...

AI-Based Registration-Free 3T T2-Weighted MRI Synthesis Using Truefisp MRI Acquired on a 0.35T MR-Linac System

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing

Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...

An Automated Notification System for Identifying Patients Eligible for Biology-Guided Radiotherapy

Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...

An Efficient Workflow for X-Ray Imaging-Based IGRT/ART

Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...

An Energy Layer Optimization Approach for Spot Scanning Proton Arc Therapy

Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan

Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...

An Explainable Classifier for Enhancing the Quality Assurance of Digital Breast Tomosynthesis Phantom Images

Authors: Hui-Shan Jian, Yu-Ying Lin

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: The image quality assurance of mammographic images is crucial for correct diagnosis. To develop and validate an explainable deep-learning classifier for phantom image quality assessment of di...

An Image Representation of Radiomics Data for Enhanced Deep Radiomics Analysis with Consideration of Feature Interactions

Authors: Xiaolong Fu, Runping Hou, Md Tauhidul Islam, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine

Abstract Preview: Purpose: To introduce a novel schematic image representation of radiomics data, called OmicsMap, for high-performance deep radiomics analysis. OmicsMap transforms tabular radiomics data into an image ...

An Integrated Robust Inverse Planning Based on AI-Built Dose Kernel Library for Preclinical Radio-Neuromodulation Using Focused Kv X-Rays

Authors: Wenbo Gu, Chenhui Qiu, Ke Sheng, Liyan Sun, Weiyuan Sun, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University, Department of Radiology, Stanford University, University of Pennsylvania, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, Stanford University,

Abstract Preview: Purpose:
The small animal radio-neuromodulation platform developed in our previous work utilized focused kV x-ray beams rotating and translating in predefined trajectories to irradiate small, mm si...

An International Multi-Institutional Espresso Study of Developing the Specialized-Equipment-Free Remote Audit for Single-Isocenter Multi-Target Stereotactic Radiosurgery

Authors: Juan-Francisco Calvo-Ortega, Andrew Cousins, Ashley Cullen, Andrew Dipulia, Peter B. Greer, Seng Boh Gary Lim, Shih-Chi Lin, D. Michael Lovelock, Conor McGarry, Victoria Robinson, Cameron Stanton, Baozhou Sun, Ching-Ling Teng, Gemma Warner, Benjamin J. Zwan

Affiliation: Northern Ireland Cancer Centre, Baylor College of Medicine, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Christchurch Hospital, Northwell, Central Coast Cancer Centre, Calvary Mater Hospital, Hospital Quironsalud Barcelona, Icahn School of Medicine at Mount Sinai, Chris O'Brien Lifehouse, University of Newcastle

Abstract Preview: Purpose: This multi-institution Electronic Silicon-based Remote Survey of Small-field Output (ESPRESSO) study aims to develop the remote audit process to evaluate the safety of single-isocenter multi-...

An Ultra-High Parallel Performance (UHPP) Framework for Highly Complex Radiotherapy Planning

Authors: Lu Jiang, Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: In radiotherapy, the conformity and compactness of dose distribution are vital to patient outcomes. The introduction of highly complex planning, such as 4Ļ€ radiotherapy, has provided a system...

Analysis of Structure Errors in Region of Interest Contouring for Radiotherapy Planning: A Study Using the RT-Contour QA Platform

Authors: Sijuan Huang, Zi LIU, Jing MA, Xin Yang

Affiliation: Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine; Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangzhou, Guangdong, 510060, China

Abstract Preview: Purpose: To reduce the pressure of manual review of abnormal situations in manually/automatically delineated regions of interest (ROI), improve its accuracy and basis.
Methods: 220 radiotherapy pat...

Artificial Intelligence (AI)-Driven Automatic Contour Quality Assurance (QA) with Uncertainty Quantification

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Accurate delineation of treatment targets and organs-at-risk is crucial for radiotherapy. Despite significant progress in artificial intelligence (AI)-based automatic segmentation tools, effi...

Assessment of Radiation Protection Knowledge Among Operation Professional Nurses

Authors: Yu-Ying Lin

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: This study aimed to evaluate the level of radiation protection knowledge among operating room professional nurses.

Methods: A questionnaire was distributed to operating room profession...

BEST IN PHYSICS THERAPY: Overcoming Challenges in Developing Machine Learning-Driven Acute Kidney Injury Predictive Models Using Non-Standard Emrs in Resource-Limited Settings

Authors: Yuanhan Chen, Ziqiang Chen, Qi Cheng, Feng Ding, Rui Fang, Shengwen Guo, Li Hao, Qiang He, Haiquan Huang, Yu Kuang, Xinling Liang, Yuanjiang Liao, Guohui Liu, Chen Lu, Qingquan Luo, Jing Sun, Yanhua Wu, Zhen Xie, Qin Zhang, Lang Zhou

Affiliation: South China University of Technology, Dongguan people's hospital, Sichuan Provincial People's Hospital, People’s Hospital of Xinjiang Uygur Autonomous Region, Second Hospital of Anhui Medical University, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangdong Easy Life Information Technology Co., Ltd, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Medical Physics Program, University of Nevada, Second Hospital of Jilin University, Chongqing Ninth People's Hospital

Abstract Preview: Purpose: Acute kidney injury (AKI) is a global healthcare issue with a rapid onset and severe consequences. Repeated measurement of serum creatinine (SCr) levels, a clinical standard of care, is cruci...

Bgrt Patient Eligibility Check Via Comparing User Defined Ring Around the Biologically Tracking Zone (BTZ) in PET Images

Authors: Resat Aydin, Brett Lewis, Jayesh Mistry, Roland Teboh

Affiliation: HUMC, Hackensack University Medical Center

Abstract Preview: Purpose:
We developed a Python-based solution to systematically quantify and detect fluorodeoxyglucose (FDG) uptake beyond a predefined Biologically Tracking Zone (BTZ) in PET images. This method i...

Breastplan-Helper: Publicly Shared Source Scripting Toolset to Assist in 3D Breast Planning

Authors: Ryan Clark, Anthony Magliari, Luis Felipe Oliveira E Silva, Yang Sheng, Jason R Vickress, Qingrong Jackie Wu, Giulianne Rivelli Rodrigues Zaratim

Affiliation: Verspeeten Family Cancer Center, Office of Medical Affairs, Varian, A Siemens Healthineers Company, Confiar Radioterapia, Duke University Medical Center

Abstract Preview: Purpose: Develop a toolset to replace several of the tedious steps required to manually generate 3D breast treatment plans using static gantry forward planned tangent beams.

Methods: Eclipse Sc...

CNN-Based Visualization for Detecting Failure Patterns of Lung SBRT through CT-Biological Effective Dose Interaction

Authors: Ashok Bhandari, Kurtis Johnson, Yu Lei, Tianzhe Li, Kyuhak Oh, Shuo Wang, Chi Zhang, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: The purpose of this study was to leverage neural network visualization tools to detect high-attention areas indicative of treatment failure in lung SBRT by examining correlation matrices betw...

Can AI Agent be a Good Judge for Online Adaptive Radiotherapy Plan Evaluation?

Authors: Steve B. Jiang, Mu-Han Lin, Dan Nguyen, Beiqian Qi, Daniel Yang, Ying Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Online adaptive radiotherapy (oART) is a resource-intensive workflow requiring significant time and effort required from clinicians, particularly for the online evaluation of plan quality....

Can Regional Radiomic Features from Pre-Treatment Computed Tomography Serve As Biomarkers for Predicting Radiation Pneumonitis?

Authors: David J. Carlson, Ming Chao, Tian Liu, Yong Hum Na, Kenneth E Rosenzweig, Robert Samstein, Lewis Tomalin

Affiliation: Icahn School of Medicine at Mount Sinai, Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To investigate the potential of regional radiomic features extracted from five lung sub-lobes on pre-treatment CT as biomarkers for predicting radiation pneumonitis (RP) using machine learnin...

Characterization of Linear Energy Transfer Spectra in Mini Beam Spatially Fractionated Proton Therapy

Authors: Serdar Charyyev, Kaan Dere, Edgar Gelover, Mohammad Khurram Khan, Liyong Lin, Mark McDonald, Cristina Oancea, Alexander Stanforth, Sibo Tian, Suk Whan (Paul) Yoon, Mingyao Zhu

Affiliation: Department of Radiation Oncology, Stanford University, Stanford University, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Advacam

Abstract Preview: Purpose: The conventional implementation of proton spatially fractionated radiotherapy (SFRT) utilizes physical collimators with apertures to generate minibeams, creating alternating regions of high-d...

Characterization, Commissioning, and Clinical Evaluation of a Commercial Beo Optically Stimulated Luminescence (OSL) System

Authors: Brett G Erickson, Joseph P. Kowalski, Xinyi Li, Qiuwen Wu, Sua Yoo

Affiliation: Duke University, Mayo Clinic - Department of Radiation Oncology, Duke University Medical Center

Abstract Preview: Purpose: Characterization and commissioning of the BeO-based myOSLchip system was performed (per TG191) to assess its feasibility as a full replacement for the recalled Landauer aluminum oxide OSL in ...

Clinical Experience with an Independent Dose Calculation Software for ZAP-X Stereotactic Radiosurgery

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: ZapMU is the first independent monitor unit check software freely available supporting ZAP-X. In this study, the clinical experience with ZapMU for independent second check of dose calculatio...

Clinical Implementation of Volumetric Modulated Arc Therapy (VMAT) for Total Body Irradiation (TBI) with Off-the-Shelf Tools

Authors: Kai-Cheng Chuang, Oana I. Craciunescu, Christopher Kelsey, Joseph Kowalski, Nicole Larrier, Xinyi Li, Sheridan G. Meltsner, Anna E. Rodrigues, Yang Sheng, Qiuwen Wu

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose: To clinically implement a Volumetric Modulated Arc Therapy (VMAT) procedure for Total Body Irradiation (TBI) with off-the-shelf tools.
Methods: Patient is treated on linac couch with a hyb...

Combining Flat-Panel Imaging and Internal BB Markers for Precise HDR Brachytherapy Source Localization

Authors: Yibin Ling, Qihui Lyu, Ke Sheng

Affiliation: University of California Berkeley, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose:
High Dose Rate (HDR) brachytherapy enables radiation to concentrate on the tumor by sending the high-dose-rate radioactive source directly to the treatment site. On the other hand, the sha...

Commission and Clinical Implementation of the 1st Step-and-Shoot Proton Arc Therapy for Head and Neck Cancer Patient Treatment

Authors: Xiaoda Cong, Rohan Deraniyagala, Xuanfeng Ding, Xiaoqiang Li, Jian Liang, Peilin Liu, Craig Stevens, Xiangkun Xu, Weili Zheng

Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital

Abstract Preview: Purpose:
Commission a step-and-shoot arc therapy(SPArc-step&shoot) for treating head-neck cancer patients as a desired interim milestone toward full dynamic treatment.
Methods:
An in-house de...

Commissioning Silicone Tissue-Compensating Bolus for Electron Beam Therapy

Authors: Carla D. Bradford, Linda Ding, Yansong Geng, Alan Hartford, I-Lin Kuo, Salvatore LaRosa, Joshua N Wancura

Affiliation: University of Massachusetts Chan Medical School

Abstract Preview: Purpose: When treating nasal skin cancers, electron beam radiotherapy dose distributions can be improved by using custom bolus to compensate for uneven surfaces. Here we describe our experience commis...

Commissioning and Validation of Monaco Proton Treatment Planning System on a Compact Proton Therapy System

Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng

Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital

Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...

Compact Representation of External Beam Photon Phase Space Data Via Implicit Neural Representation Learning

Authors: Serdar Charyyev, Cynthia Fu-Yu Chuang, Veng Jean Heng, Lianli Liu, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: To replace large finite-size photon phase space files with a compact neural network capable of generating an infinite number of particles.
Methods: Three separate models were developed to ...

Comparing Planned Vs. Delivered Bladder Dose-Toxicity Associations in Prostate Cancer Radiotherapy: Insights from the Mirage Trial

Authors: Minsong Cao, Amar Kishan, Yi Lao, An Liu, Beth Neilsen, X. Sharon Qi, Kun Qing, Ke Sheng, Michael Steinberg, Luca F Valle, Terence Williams

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, City of Hope Medical Center, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To investigate the clinical relevance of planned versus delivered doses in toxicity associations utilizing localized assessment of genitourinary (GU) toxicity in bladder subregions among pros...

Comparison of Clinical Virtual Unenhanced and True Unenhanced Images on a Prototype Deep Silicon Photon-Counting Detector CT

Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue

Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology

Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...

Comprehensive Evaluation of High-Performance Cone-Beam Computed Tomography on C-Arm and Ring-Gantry Linacs for Adaptive Radiation Therapy

Authors: Laura I. Cervino, Karen Episcopia, Hsiang-Chi Kuo, Sangkyu Lee, Seng Boh Gary Lim, Shih-Chi Lin, Grace Tang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study evaluated the performance of the HyperSight Cone-Beam Computed Tomography (CBCT) system on a TrueBeam C-arm LINAC (TB) and two Ethos ring-gantry LINACs (ES) for adaptive radiation ...

Construction and Application Study of a Deep Learning-Based Iscout-Guided Precision Radiotherapy Positioning Error Prediction Model for Breast Cancer

Authors: Fangfen Dong, Jiaming Li, Xiaobo Li, Weipei Wang, Zhixin Wang, Bing Wu, Benhua Xu, Yong Yang, Yifa Zhao

Affiliation: Department of Radiation Oncology, Fujian Medical University Union Hospital/Fujian Key Laboratory of Intelligent Imaging and Precision Radiotherapy for Tumors/Clinical Research Center for Radiology and Radiotherapy of Fujian Province (Digestive, Hematologi, Zhangpu County Hospital, School of Medical Imaging, Fujian Medical University

Abstract Preview: Purpose: To explore the construction and clinical application value of a deep learning-based positioning error prediction model, providing a reference for optimizing iSCOUT system-guided precision rad...

Correction Factors for Estimating Skin Dose from Overresponse of Two Commercial Optically Stimulated Luminescence Dosimeters

Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son

Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine

Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...

Cross Characterization of a 3D Gamma Camera and Ring Brachytherapy Applicator

Authors: Zachary R. Grelewicz, Kevin C. Jones, Yixiang Liao, Andrew Ogilvy, Julius V. Turian

Affiliation: Rush University Medical Center

Abstract Preview: Purpose: To demonstrate the accuracy and QA application of a time-resolved 3D gamma camera, we measured the path traversed by the Ir-192 High-Dose-Rate (HDR) brachytherapy source passing through a rin...

Dedicated Cone-Beam Breast CT: Investigation on the Effect of Lesion Type on Detectability Index Using Cascaded Systems Analysis.

Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham

Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona

Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...

Deep Learning-Based Eye Monitoring and Tracking System for Ocular Proton Therapy in a Regular Gantry Room

Authors: David H. Abramson, Christopher Barker, Jasmine H. Francis, Meng Wei Ho, Yen-Po Lee, Haibo Lin, Hang Qi, Andy Shim, Charles B. Simone, Weihong Sun, Xiaoxuan Xu, Siyu Yang, Francis Yu, Anna Zhai

Affiliation: College of Machine Intelligence, Nankai University, New York Proton Center, Department of Biomedical Engineering, Johns Hopkins University, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Proton therapy is an effective modality for treating ocular tumors such as uveal melanoma. We developed a novel camera‐based eye‐tracking system to provide real-time noninvasive eye positioni...

Deep Learning-Based Segmentation Using Cine Epid Images for Real-Time Tumor Monitoring

Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita

Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital

Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...

Dependency of CT Number on Position in the Field-of-View for Single- and Multi-Energy Images Acquired with Energy-Integrating-Detector and Photon-Counting-Detector CT Scanners

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...

Design of Next Generation Hemispherical Brain PET System Aiming for 1mm Resolution

Authors: Go Akamatsu, Yuma Iwao, Kurumi Narita, Hideaki Tashima, Taiga Yamaya, Eiji Yoshida

Affiliation: National Institutes for Quantum Science and Technology

Abstract Preview: Purpose: In brain positron emission tomography (PET), higher spatial resolution is better for visualizing detailed structures such as small nuclei and the layered structure of the cerebral cortex. The...

Determination of HU Override for Small Metal Implants in Proton Therapy

Authors: Matthew Stephen Andriotty, Taoran Cui, Harold Y Hu, Ke Nie, Tan Phan, Xiao Wang, Ning J. Yue, Chengzhu Zhang

Affiliation: Rutgers Cancer Institute of New Jersey, Basis Scottsdale

Abstract Preview: Purpose: Metallic implants are often non-isocentric, and their exact volumes/orientations/shapes are difficult to capture and contour accurately on CT images even if that information is known beforeha...

Determine the Isocenter and Its Size for MR Linac Unity Part1: (U V) of Cax

Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang

Affiliation: NYU Langone Health

Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...

Development and Clinical Validation of Hyperarc Stereotactic Radiosurgery Method for Intraocular Tumors

Authors: Chase Cochran, Damodar Pokhrel, William St Clair

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...

Development and Implementation of MRI-Only Simulation, Planning and Treatment Workflow for Pelvic Radiotherapy Using Synthetic CT on MR-Linac

Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao

Affiliation: The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...

Development and Validation of a Principal Component Analysis Statistical Shape Pediatric/Adolescent Breast Model for Pre-CT Era Breast Dose Reconstruction in Late Effect Studies of Female Childhood Cancer Survivors

Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte

Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Children’s Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Children’s Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences

Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...

Development and Validation of an MR-Compatible Anthropomorphic Motion Phantom for Liver Motion Assessment and MR-Linac Gating System Optimization

Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...

Development of a Brain-like Digital Reference Object of Resting-State Functional MRI

Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo

Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...

Development of a GPU-Based Dose Calculation Engine for MRI-Guided Proton Therapy

Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...

Development of a Proton CT System Based on 2D Scintillation Detection

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China

Abstract Preview: Purpose: To develop a proton CT system using scintillator-based 2D dose distribution detection for accurate proton imaging.
Methods: The proposed proton CT system consists of a brass collimator wit...

Development of an Inverse Treatment Planning System for Precision Small Animal Radiotherapy

Authors: Zihao Liu, Qiwei Wu, Yanfei Xiong, Yidong Yang, Ning Zhao

Affiliation: Department of Engineering and Applied Physics, School of Physical Sciences, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose: To develop an inverse planning framework that optimizes beam angles and intensities for small animal radiotherapy and to validate its accuracy and effectiveness.
Methods: The inverse plann...

Diffusion Model-Based Motion Correction in Portable Computed Tomography for Brain: Human Observer Study

Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...

Dosimetric Assessment of Multicriteria Optimization for Accelerated Partial Breast Irradiation (APBI)

Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...

Dosimetric Evaluation of Comprehensive Motion Management in 1.5T MR-Linac for Real-Time Gated Radiotherapy

Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Pak Hang Nam, Mei Yan Tse, Jierong Wang, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung

Affiliation: Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: Intrafraction motion management remains a major challenge in magnetic resonance-guided radiotherapy (MRgRT). The recent clinical release of an active motion management system aims to enhance ...

Dosimetric Evaluation of a Three-Dimensional Cubic Electronic Detector Array for Radiotherapy Linac Quality Assurance

Authors: Enzo Charles Aucca, Roger Challco, Andres M. Gonzales Galvez, Carmen SANDRA Guzman Calcina, Jimmy Hernandez-Bello, Modesto Montoya, Renzo Aaron Ocampo, Erick Paniagua, Miguel Alberto Risco-Castillo, Dante E. Roa, Renzo E. Romero, William Souza Santos, Mirko Salomón Alva SÔnchez

Affiliation: Graduate Program in Information Technologies and Health Management, University of Porto AlegreFederal University of Health Sciences of Porto Alegre, Universidad Tecnologica del Peru, Pontificia Universidad Catolica del Peru, Electronic Engineering Department, Leonard Cancer Institute - Radiation Oncology, Universidad Nacional de Ingenieria, Universidad Nacional de Ingenieria, Electronic Engineering Department, Federal University of Sergipe, HRS Oncology International, Universidad Nacional Federico Villareal

Abstract Preview: Purpose: Provide Monte Carlo (MC) and experimental dosimetric assessments of a 3D cubic electronic detector array based on percent depth doses (PDDs), profiles, linearity, and dose rate response of ph...

Dosimetric Evaluation of the Aldo Function for Multiple Brain Metastases in Automated Stereotactic Radiosurgery Treatment Planning

Authors: Hsiao-Mei Fu, Shih-Ming Hsu, Chia-Ting Lee, Shih-Hua Liu, Tsung-Yu Yen

Affiliation: National Yang Ming Chiao Tung University, Mackay Memorial Hospital

Abstract Preview: Purpose: The Automatic Lower Dose Objective (ALDO) is a unique function designed to achieve 98% relative coverage across all targets in automated SRS treatment planning (HyperArc planning). This study...

Dosimetric Impact of Adaptive Radiotherapy with Ethos for Prostate Cancer: Localized Analysis of Bladder and Rectum across Planned, Non-Adaptive Accumulated, and Adapted Treatments

Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu

Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center

Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...

Dosimetric Impact of Monte Carlo Physics Models in Electronic Brachytherapy Simulations

Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaƫl Ndoutoume-Paquet, Jan P. Seuntjens, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson

Affiliation: DƩpartement de physique, de gƩnie physique et d'optique, UniversitƩ Laval, Princess Margaret Cancer Centre & University of Toronto, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique MƩdicale et de Radioprotection, Centre IntƩgrƩ de CancƩrologie, CHU de QuƩbec- UniversitƩ Laval et Centre de recherche du CHU de QuƩbec, Nuclear Medicine Department, Hospital Regional de Antofagasta, UniversitƩ Laval, Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University

Abstract Preview: Purpose: Low-energy X-ray beams used in electronic brachytherapy (eBT) pose unique dosimetric challenges due to high depth-dose gradients, material-dependent detector responses, and the absence of sta...

Dosimetric Impact of Target Coverage with Inter-Fraction Patient Yaw Setup Error in IMRT/VMAT Prostate Cancer Radiotherapy

Authors: Min Su

Affiliation: Mount Sinai School of Medicine

Abstract Preview: Purpose: To evaluate dosimetric impact of patient setup yaw error to target coverage for pelvis/prostate radiation external beam IMRT-VMAT treatment.
Methods: 9 Pelvis/prostate IMRT-VMAT treatment ...

Dosimetric Impact on Patient Roll/Yaw Change for Whole Breast 3D Radiotherapy

Authors: Min Su

Affiliation: Mount Sinai School of Medicine

Abstract Preview: Purpose: To evaluate dosimetric impact of target coverage and organ at risk (OARs) sparing for whole breast patient setup roll/yaw change in 3D-conformal radiotherapy.
Methods: 8 whole breast cases...

Dosimetry Commissioning of a Commercial Cabinet X-Ray Irradiator for Small Animal Irradiation

Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal

Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center

Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...

Dosimetry Impact of Overlapping Reconstruction of CT Simulation in Stereotactic Radiosurgery Planning

Authors: Matthew Stephen Andriotty, Chi Ma, Xiao Wang, Keying (Karen) Xu, Suhong Yu, Ning J. Yue, Yin Zhang

Affiliation: Brigham and Women's Hospital, Rutgers Cancer Institute of New Jersey

Abstract Preview: Purpose: To evaluate the effects of overlapping CT reconstruction on dosimetry calculation for LINAC-based SRS patients simulated on CT simulators from three different vendors.
Methods: CT simulati...

Early Evaluation Study for Stereotactic Adaptive Radiotherapy for Pancreatic Cancer with Ethos 2.0 System

Authors: Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Rojano Kashani, Kyle O'Carroll, Gisele Castro Pereira, Christian Erik Petersen, Alex T. Price, Meiying Xing, Reine abou Zeidane

Affiliation: university hospital, University Hospitals Seidman Cancer Center

Abstract Preview: Purpose:
Experimental data have shown the inconsistent monitor unit and target coverage in Ethos 1.1. This can lead to inaccurate dose delivery, compromising patient safety and treatment outcomes. ...

Effects of Plan Optimization Techniques on Relative Biological Effective Dose in a Thin Intracranial Target Volume

Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch

Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center

Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...

Electronic Brachytherapy Dosimetric Reference Datasets Using Model-Based Dose Calculation Algorithms

Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaƫl Ndoutoume-Paquet, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson

Affiliation: DƩpartement de physique, de gƩnie physique et d'optique, UniversitƩ Laval, Laval University, Princess Margaret Cancer Centre, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique MƩdicale et de Radioprotection, Centre IntƩgrƩ de CancƩrologie, CHU de QuƩbec- UniversitƩ Laval et Centre de recherche du CHU de QuƩbec, Nuclear Medicine Department, Hospital Regional de Antofagasta

Abstract Preview: Purpose: Modelling electronic brachytherapy (eBT) sources is difficult because of the high-dose gradients and challenges associated with low-energy modelling. This study examines the accuracy of avail...

Enhanced Lung Function Assessment through Machine Learning Analysis of 4DCT Subregional Respiratory Dynamics

Authors: Jing Cai, Zhi Chen, Hong Ge, Yu-Hua Huang, Bing Li, Zihan Li, Ge Ren

Affiliation: Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital

Abstract Preview: Purpose: Algorithms based on subregional respiratory dynamics (SRD) capture spatiotemporal heterogeneity in the ventilation process, though rely on empirical modelings to map surrogate ventilation. Gi...

Enhancing Dose Conformity in Halcyon SRS Plans: A Novel Approach Using Optimized Collimator Angles and Sub-Arcs.

Authors: David Chighvinadze, Chieh-Wen Liu, Sugandima Weragoda, Ping Xia

Affiliation: Cleveland Clinic Sandusky, Cleveland Clinic

Abstract Preview: Purpose: To explore the feasibility of using coplanar beams with collimator angle optimization for brain SRS plans with Halcyon system.
Methods: This study used a dataset of 26 patients with 2-3 br...

Enhancing Radiotherapy Planning with Machine Learning: Correlating Anatomical Features and Planning Difficulty to Guide Optimal Plan Design

Authors: Li Chen, Shouliang Ding, Xiaoyan Huang, Lecheng Jia, Hua Li, Hongdong Liu, Yanfei Liu, Zun Piao, Guangyu Wang

Affiliation: State Key Laboratory of Oncology in South China, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Shenzhen United Imaging Research Institute of Innovative Medical Equipment

Abstract Preview: Purpose: Optimal radiotherapy planning is challenging, influenced by anatomical factors such as surrounding organs and tumor characteristics, which complicate dose distribution and target coverage. Wh...

Establishing Comprehensive QA for Single-Isocenter Multiple Targets Stereotactic Radiosurgery

Authors: Angel Gomez, Titania Juang, Grace Gwe-Ya Kim, Boyu Meng

Affiliation: UC San Diego, UCSD, University of California San Diego

Abstract Preview: Purpose: Single-Isocenter Multiple Targets (SIMT) Stereotactic Radiosurgery (SRS) is widely used for its precision and effectiveness. However, standardized quality assurance (QA) protocols for SIMT SR...

Establishing a Protocol for Quality Assessment of Ultrasound Shear Wave Elastography (SWE) and Application to a Musculoskeletal (MSK) Task

Authors: Kevin M Brom, Jaydev K. Dave, Chunming Gu, Nicholas J. Hangiandreou, Zaiyang Long, Donald J Tradup

Affiliation: Mayo Clinic

Abstract Preview: Purpose: Ultrasound scanner onboard quality checks for shear wave elastography (SWE) rely on operator judgement and are insufficient. This study aims to establish a protocol for quality assessment and...

Evaluating Supervised Learning Models for Binary Classification of Radiomic Data in Predicting Head and Neck Cancer Treatment Outcomes

Authors: Theodore Higgins Arsenault, Kyle O'Carroll, Christian Erik Petersen, Alex T. Price, Meiying Xing

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To assess the performance of various supervised learning models’ ability to predict binary classification of radiomic data for head and neck (H&N) cancer treatment outcomes.
Methods: Using...

Evaluating Tumor Shrinkage Using Fractionated Radiotherapy: A Mixed Finite Element Method (FEM) for Free Boundary Problem

Authors: Xianjin Dai, PhD, Xiang Wan, Lei Xing, Qiuyun Xu, Lewei Zhao, Zeyu Zhou

Affiliation: Department of Radiation Oncology, Stanford University, Carl Zeiss X-ray Microscopy, Department of Mathematics and Statistics, Loyola University Chicago, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: The purpose of this study is to examine and quantify tumor shrinkage over time in response to fractionated radiotherapy. We seek to establish a predictive model that can provide a systematic ...

Evaluating the Performance of Using Large Language Models to Automate Summarization of CT Simulation Orders in Radiation Oncology

Authors: Meiyun Cao, Edward L. Clouser, Xiaoning Ding, Jason Michael Holmes, Shaw Hu, Linda L. Lam, Wendy S. Lindholm, Wei Liu, Samir H. Patel, Diego Santos Toesca, Jason Sharp, Sujay A. Vora, Peilong Wang

Affiliation: Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, George Washington University

Abstract Preview: Purpose: In current clinical workflow of radiation oncology departments, therapists manually summarize CT simulation orders into summaries before the CT simulation for execution. This process signific...

Evaluation of Hybrid Dynamic Conformal Arc Planning for SRS and SBRT Treatment

Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...

Evaluation of Lead Glasses Efficiency in Reducing Eye Radiation Exposure during Angiography Using Optically Stimulated Luminescence Dosimeters

Authors: Yu-Ying Lin, Yu Chen Shen

Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou

Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...

Evaluation of Plan Quality and Optimal Isocenter Arrangement for Total Marrow and Lymphoid Irradiation on a Ring-Gantry Linac with Dual-Layer Mlc Using the Knowledge-Based Planning Technique

Authors: Chunhui Han, An Liu, Anthony Magliari, Lesley Rosa

Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To evaluate the performance of a knowledge-based planning (KBP) optimization model for total marrow and lymphoid irradiation (TMLI) on a ring-gantry linac with a dual-layer MLC and to evaluat...

Evaluation of Potential Dosimetric Risks from Intra-Fractional Motion in Single-Isocenter Stereotactic Radiosurgery

Authors: Brian D. Casto, Mathew Y Kang, Lichung Ku, Samuel J Wang, Joseph B. Ying, Walker Ray Zimmerman

Affiliation: Salem Health Cancer Center, Salem Health

Abstract Preview: Purpose: Varian HyperArc is an advanced radiotherapy module designed to efficiently deliver high-quality multi-target stereotactic radiosurgery (SRS) treatment plans on Varian linacs. However, the int...

Evaluation of Synaptive MRI Geometric Distortion with Sun Nuclear MR Distortion and Image Fusion Head Phantom

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Jing Feng, Wenzheng Feng, Joseph Hanley, Jeff Stainsby, Tingyu Wang

Affiliation: Synaptive Medical, Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose:
The Synaptive MRI is a 0.5T superconducting head only system (first US install 2023). This is the first study that evaluates the geometric accuracy using a Sun Nuclear MR Distortion and Im...

Evaluation of Thoracic Direct Dose Calculation Using Truebeam Linac with Hypersight Imaging CBCT Solution

Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Alex T. Price, Sagar Regmi, Atefeh Rezaei, Runyon C. Woods

Affiliation: University Hospitals Seidman Cancer Center

Abstract Preview: Purpose: To investigate the feasibility and accuracy of using a Hounsfield Unit(HU) calibrated cone-beam computed tomography(CBCT) for direct dose calculation in thoracic treatment settings. In combin...

Evaluation of Time Delays in a Surface-Guided Radiotherapy-Based Gating System Using Exactrac Dynamic and Truebeam Linear Accelerator

Authors: Hiroki Katayama, Hiroki Kawasaki, Motonori Kitaoka, Yosuke Takahashi, Takashi Tanii, Masato Tsuzuki

Affiliation: Kagawa University Hospital

Abstract Preview: Purpose:
Surface-guided radiotherapy (SGRT) with ExacTrac Dynamic (ETD) allows motion tracking and beam gating during treatment delivery. Accurate evaluation of beam-on and beam-off delays is essen...

Evaluation of a New Radiation Imaging Survey Meter for Treatment Room Cleanup Following Lu-177 and I-131 MIBG Therapy.

Authors: Steven Brown, Mike Hopkins, Jerimy C. Polf, Scott Sawyer, Benjamin L. Viglianti

Affiliation: H3D, inc, University of Michigan, M3D, Inc, M3D Imaging

Abstract Preview: Purpose: To evaluate the potential of a radiation imaging survey meter (RISM) to improve detection and efficiency/speed for radiopharmaceutical therapy (RPT) suite clean up after patient treatment has...

Evaluation of the Dosimetric Characteristics of Multi-Layers of Brass Mesh Bolus for Electron Treatment

Authors: Yunzhi Ma, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: Multiple layers of brass mesh bolus (RPD, Inc., Albertville, MN) may be needed to provide better body conformity and sufficient dose build up on patient surface during electron treatment. Thi...

Evaluation of the Geometric Integrity of Elekta MR/CT Tandem and Ring Applicator Models for Brachytherapy

Authors: Jingxi Weng, Jian Wu

Affiliation: University of Florida

Abstract Preview: Purpose: Modern brachytherapy treatment planning software includes pre-defined applicator models. However, previous studies have shown significant discrepancies between actual and model-based first dw...

Evaluation of the Reflexion X1 As a Standalone PET/CT Simulator for Treatment Planning and Treatment Adaptation

Authors: Chunhui Han, An Liu, William T. Watkins, Qiuyun Xu

Affiliation: Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: To evaluate the RefleXion X1 imaging system as a standalone positron emission tomography and computed tomography (PET/CT) simulator for radiotherapy treatment planning and adaptive re-plannin...

Feasibility Study of the Auger Electron Radiation Therapy

Authors: Chen-Ju Feng, Shih-Ming Hsu, Chin-Hsiung Lin, Shih-Yong Luo, Shao-Chun Tseng, Chin-Hui Wu, Ya-Ru Yang

Affiliation: National Yang Ming Chiao Tung University, Koo Foundation Sun Yat-Sen Cancer Center, Tzu-Chi University, NanoRay Biotech Co., Ltd

Abstract Preview: Purpose: The range of auger electrons in water is 2~500 nm, and its linear energy transfer reaches 26 keV/μm. This study investigated the feasibility of the auger electron radiation therapy.
Method...

First in-Vivo Application of a Novel Precision Small Animal Irradiation Platform with Proton IMPT Delivery and Advanced on-Board Image-Guidance

Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers Sørensen, Peter Thirolf

Affiliation: Department of Medical Physics, Ludwig-Maximilians-Universität München (LMU Munich), Ludwig-Maximilians Universität, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-Universität (LMU) München, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital

Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...

Flash Radiation Spares Reproductive Capability in Adult C. Elegans

Authors: Barry Andricks, Stratton Black, Scott R. Floyd, Ashutosh Kotwal, Eric L. Martin, Stepan Mikhailov, Mark Oldham, Niccolo Terrando, Andrew Thompson, Ying Wu

Affiliation: Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University, Department of Radiation Oncology, Duke University Medical Center, Triangle Universities Nuclear Laboratory

Abstract Preview: Purpose: To evaluate and quantify the effects of high energy electron radiation delivered at FLASH and conventional dose rates on the reproductive capability of adult C. elegans nematodes.
Methods:...

Foundation Models with Balanced Data Sampling Enhance Auto-Segmentation for Cardiac Substructures

Authors: Chloe Min Seo Choi, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Cardiac substructure irradiation predisposes patients for poor outcomes in thoracic radiation therapy. A deep learning model was developed to segment the cardiac substructures invariant to co...

Frameless and Maskless Stereotactic Radiosurgery: Evaluating a Novel Robotic Head Motion Compensation Device

Authors: Michelle Alonso-Basanta, Carl Denis, Wenbo Gu, Xinmin Liu, Ahmad Sakaamini, Rodney D. Wiersma

Affiliation: UCLA, University of Pennsylvania, CDR Systems

Abstract Preview: Purpose: Stereotactic radiosurgery (SRS) is a non-invasive technique used to treat functional abnormalities and small brain tumors. Traditional SRS relies on a rigidly fixed metal head ring, causing d...

Free-Breathing Spirometer-Gated Proton Pencil Beam Scanning Delivery Maintains Tumor Coverage with Improved Organ-at-Risk Sparing: A Motion Phantom Validation

Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng

Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...

Functional MRI Guided Partial Tumor Irradiation to Improve Tumor Control and Spare Tumor Microenvironment

Authors: Bingqi Guo, Ping Xia

Affiliation: Cleveland Clinic

Abstract Preview: Purpose:
Spatially fractionated radiation therapy (SFRT) delivers a ā€œGRIDā€ or ā€œlatticeā€ of high and low doses to tumors to increase tumor control, minimize normal tissue damage, and preserve the im...

GPU-Accelerated Beamlet and Full Dose Calculations for Efficient Radiation Therapy Planning

Authors: Girish Bal, Jan Kralj, Ayan Mitra, PhD, Ling Shao, Matjaz Subic, Yevgen Voronenko

Affiliation: RefleXion Medical, Cosylab

Abstract Preview: Purpose: This work enhances the efficiency of radiation therapy treatment planning by optimizing the beamlet dose matrix and full patient dose computations using GPU acceleration. The Collapsed-Cone C...

Gaze Angle Selection in Proton Therapy for Ocular Tumors with Machine Learning

Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu

Affiliation: Massachusetts General Hospital, MGH

Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...

High-Fidelity Treatment Optimization for Online Adaptive Stereotactic Partial Breast Irradiation: Integrating Dose and Treatment Time Considerations

Authors: Drexell Hunter Boggs, Carlos E. Cardenas, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Courtney Bosse Stanley, Dennis N. Stanley, Sean Xavier Sullivan, Natalie N. Viscariello

Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, University of Alabama at Birmingham

Abstract Preview: Purpose: CBCT-guided online adaptive radiation therapy (OART) with Ethos for stereotactic accelerated partial breast irradiation (APBI) can mitigate inter-fraction variation, leading to dosimetric adv...

High-Resolution Limited-Angle CBCT Image Reconstruction for Non-Coplanar Radiation Therapy Via Dual-Domain Ordered-Subset Neural Representation with Prior Embedding (DDOS-NeRP)

Authors: Yu Gao, Lei Xing, Siqi Ye

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...

High-Temporal Dynamic CBCT Imaging Via Gaussian Neural Representation

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study introduces a novel spatiotemporal Gaussian neural representation framework to reconstruct high-temporal dynamic CBCT images from 1-minute acquisition, preserving motion dynamics an...

Image Quality Enhancement for Transrectal Ultrasound Imaging of Prostate Brachytherapy Using Deep Learning: A Needle Eraser

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...

Impact of Breathing Trace on Gating Uncertainty

Authors: William P. Donahue, Lauren Smith, Shu (Stella) Xing

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: To quantify the dosimetric uncertainty of end-exhale gating as a function of breathing pattern.

Methods: A Truebeam delivered AP square fields to EBT4 film placed in the Quasar MRI4D M...

Impact of Patient Size on the Choices of Dual and Single Energy CT for Accurate Liver Fat Volume Fraction Quantification

Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou

Affiliation: University of Kentucky, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...

Inter-Patient Registration Methods for Voxel-Based Analysis in Lung Cancer

Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...

Introduce a Novel Spot-Scanning Proton Arc(SPArc) Optimization Algorithm for Single Energy Extraction(SEE) Synchrotron-Accelerator-Based Proton Therapy System (PTS)

Authors: Xiaoda Cong, Xuanfeng Ding, Gang Liu, Peilin Liu, Jiajian Shen

Affiliation: Department of Radiation Oncology, Mayo Clinic, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Corewellhealth William Beaumont University Hospital

Abstract Preview: Purpose: This study aims to develop the first SPArc optimization algorithm based on the Dynamic Programming (SPArc-DP), to improve the treatment delivery efficiency for synchrotron-accelerator-based P...

Investigating the Dosimetric Benefits of Enhanced Solid Angle Accessibility in a Self-Shielded Radiosurgery System

Authors: Peter Jermain, Ying Niu, Abdul Rashid, Yuan Yuan, Mohammad Zarenia

Affiliation: Medstar Georgetown University Hospital, MedStar Georgetown University Hospital, Department of Radiation Medicine, MedStar Georgetown University Hospital

Abstract Preview: Purpose: ZAP-X is a self-shielded radiosurgery system that utilizes a linac-based isocentric technique and a compact gyroscopic gantry design. While it provides a large solid angle for beam orientatio...

Investigating the Flash Effect: Uncovering Brain Sparing and Cognitive Preservation across Varying Dose Rates in Whole-Brain Irradiation of in-Vivo Mouse Models

Authors: Denise Dunn, Scott R. Floyd, Tyler V. Kay, Anna Lynnette-Price, Eric L. Martin, Stepan Mikhailov, Taylor Nguyen, Mark Oldham, Victoria J. P. Radosova, Zachary J. Reitman, Ramona Rodriguiz, Andrew Thompson, William Wetsel, Seth Wilcox, Ying Wu

Affiliation: Duke University Mouse Behavior Core, Department of Physics, Duke University, Medical Physics Graduate Program, Duke University, Duke University Medical Physics Program, Duke University, Duke University Mouse Behavioral and Neuroendocrine Analysis Core Facility, Department of Radiation Oncology, Duke University Medical Center

Abstract Preview: Purpose: FLASH radiation therapy (RT) shows promise for reducing normal tissue damage, though its mechanisms remain unclear. Using an in-vivo model with the High Intensity Gamma-ray Source (HIGS) lina...

JACK KROHMER EARLY-CAREER INVESTIGATOR COMPETITION WINNER: Direct Measurement of an Early Change in Tumor Oxygenation in Response to Radiation with Oxygen Enhanced Electron Paramagnetic Resonance Imaging (OE-EPRI)

Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou

Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...

Leveraging Hybrid Quantum Solvers for Eye Plaque Brachytherapy Treatment Planning Optimization

Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...

Liver Tumor Auto-Contouring Using Recurrent Neural Networks on MRI-Linac for Adaptive Radiation Therapy

Authors: Yan Dai, Jie Deng, Christopher Kabat, Weiguo Lu, Ying Zhang, Hengrui Zhao

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
MRI-guided adaptive radiotherapy (MRgART) using MR-LINAC systems offers significant advantages for liver cancer, enabling superior tumor delineation and online plan adaptation. However, ma...

Long-Term Stability Assessment of an Imaging Ring System Using One Year of Monthly Quality Assurance Data

Authors: Awens Alphonse, Nebi Demez, Brian P. Laffey, Shyam Pokharel, Suresh Rana, Nishan Shrestha

Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida

Abstract Preview: Purpose: The Imaging Ring is a mobile digital X-ray system capable of producing 2D planar X-rays, fluoroscopy, and 3D Cone-Beam Computed Tomography (CBCT) images. This study aimed to evaluate the long...

Lu-177 Recovery Coefficients Using Tc-99m Surrogate Method: Intra- & Inter-Scanner Comparison

Authors: Ben Piacitelli, Celeste Winters

Affiliation: OHSU, Department of Diagnostic Radiology, Oregon Health & Science University

Abstract Preview: Purpose: To compare recovery coefficients measured with Lu-177 and Tc-99m with the goal of assessing accuracy of the Tc-99m surrogate method and comparing RC reproducibility between scanners of the sa...

MRI Radiomics-Based Machine Learning Model for Predicting BNCT Treatment Response in Glioblastoma

Authors: Huang Chi-Shiuan, Wu Chih-Chun, Hui-Yu Cathy Tsai, Chen Yan-Han, Chen Yi-Wei, Pan Yi-Ying

Affiliation: Institute of Nuclear Engineering and Science, National Tsing Hua University, Taipei Veterans General Hospital, Tri-Service General Hospital

Abstract Preview: Purpose:
This study aims to develop and validate a machine learning (ML) model based on MRI-derived radiomic features to predict progressive disease (PD) in glioblastoma (GBM) patients four months ...

Mask Guided Diffusion Model for Metal Artifacts Reduction

Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Metallic implants can significantly distort sinograms, leading to severe artifacts in computed tomography (CT) reconstructions. Reconstructing CT images containing metal is fundamentally an i...

Mitigating Data-Driven Uncertainty in Machine Learning-Based Radiotherapy Outcome Prediction

Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu

Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich

Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...

Monitor Unit (MU) Substructure Analysis for Low MU Deliveries

Authors: Indra J. Das, Ahtesham U. Khan, Andrew J. White, Poonam Yadav

Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine

Abstract Preview: Purpose: During intensity modulated radiotherapy (IMRT) planning, low MU segments (< 3 MU) are commonly avoided due to documented dosimetric nonlinearity and poor reproducibility. This work aims to ex...

Multi-Region Multiomic Features Improve Random Forest Toxicity Modeling of Radiation Pneumonitis

Authors: Laurence Edward Court, Alexandra Olivia Leone, Zhongxing Liao, Saurabh Shashikumar Nair, Joshua S. Niedzielski, Ramon Maurilio Salazar, Ting Xu

Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Radiation Pneumonitis (RP) predictive models often rely on clinical and DVH parameters, but multiomic features from CT imaging and 3D dose distributions from various regions could provide add...

Multimodal Framework for Predicting Radiation-Induced Severe Acute Esophagitis in Esophageal Cancer

Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu

Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University

Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...

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Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik PeruŔko, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, Maíra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo Castañeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum

Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. Hershey Med Ctr., New York Weill Cornell Medical Ctr, X-Ray Computations, Inc., US Navy, Penn State Health, Kelsey Seybold Clinic, Advocate Aurora, Fresno Cancer Center, Central Alabama Radiation Oncology, Riverside Methodist Hospital Ohio Health, Alliance Medical Physics, OCSRI, AAPM, University of Minnesota, University of Virginia Health System, PGIMER, Barrigel, Johns Hopkins Univ, Appex Physics Partners, BoxElder Research, University of Oklahoma Health Sciences Center, Sanford Roger Maris Cancer Center, Berkshire Medical Center, New York Weill Cornell Medicine, Mobimed Technologies, University of Chicago Medicine, Johns Hopkins Medicine, Maimonides Medical Center, Nuvance Health - Vassar Brothers, Crozer Keystone Health System, Karmanos/McLaren, Vanderbilt University, Panhandle Cancer Care Center, The University of Michigan, Piedmont Healthcare, Gamma Medical Physics LLC, Mississippi Baptist Medical Center, Astarita Associates Inc, Landauer Medical Physics, RPS Oncology, Zhejiang University, University of North Carolina School of Medicine, University of Kentucky HealthCare, Peninsula Regional Medical Center, Varian Advanced Oncology Solutions, New York Proton Center, Wake Forest University Medical Center, Rutgers Robert Wood Johnson Medical School, Tx Oncology, Lewis Hall Singletary Oncology Center (John D. Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. 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Ohio Medical Physics Consulting, West Michigan Cancer Center, University Hospitals Cleveland Medical Center, Levine Cancer Institute/Atrium Health, Advanced Biophotonics Laboratory, University of Massachusetts Lowell, UConn Health, U.S. Nuclear Regulatory Commission, Wayne State University, University of Oklahoma Health Science Center, Houston Methodist Hospital, Varian, Arizona Center for Cancer Care, NIH Clinical Center, Stanford University, Hospital of the University of Pennsylvania, Peel Regional Cancer Center, Credit Valley Hospital, University of Alabama Birmingham, Lark Physics, Ackerman Cancer Center, Southern District Health Board, Milestone Medical Physics Group, UTHealth Houston McGovern Medical School, Rutgers University, West County Radiological Group, Mayo Clinic, Philips Healthcare, University of Vermont Medical Center, Novant Health at Presbyterian Medical Center, Harvard Medical School, Ratio Therapeutics, Naval Medical Center Portsmouth, University Colorado Denver, School of Medicine, Sutter Santa Cruz Radiation Oncology, Radiophysics Associates, Northside Hospital, SolutionHealth, University of Virginia Health Systems, Johns Hopkins School of Medicine, Austin Health, UPMC, St. Joseph Mercy Health System, Cancer Center of Hawaii, Centra Health, Aspekt Solutions, Winter Haven Hospital, Henry Ford Hospital System, Medical University of South Carolina, Maine Medical Center, Phoenixville Hospital, National Institutes of Health, Associated Medical Professionals, Gundersen Health System, St. Luke's University Health Network, Univesity of Victoria, Department of Radiation Oncology, Stanford University School of Medicine, Washington University in St. Louis, Queen's Medical Center, West O'ahu, Canon Medical Research USA, Inc., Robert Wood Johnson University Hospital, UVA Health System, Section for Biomedical Physics, Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University Tübingen, Centennial Medical Physics, McLaren Cancer Institute, Cancer Care Group, Texas Oncology-Tyler, CTSI Oncology Practice Solutions, a varian company, Bank of Cyprus Oncology Centre, Columbus Regional Hospital, Central Florida Cancer Insititute, Texas Oncology - San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren – Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University

Abstract Preview: N/A...

Neural Implicit K-Space for Accelerated Patient-Specific Non-Cartesian MRI Reconstruction

Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang

Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.

Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...

Neutron Dose Measurements with Multiple Dosimetry Techniques for Fetal Dose Estimation

Authors: Ahmet S. Ayan, Estelle Batin, Austin M. Faught, Peter E. Klages, Eunsin Lee, Collin Nappi, Mina Okello, Meghana Ramani, Zachary X. Richards, Parisa Sadeghi

Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University

Abstract Preview: Purpose: Neutron doses are not modelled in proton treatment planning systems, so measurements were taken with two independent dosimeter types to quantify representative neutron fetal doses in pencil b...

Novel Approach to Improve Treatment Planning Process for Mixed Fractionation Schemes on ZAP-X

Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang

Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center

Abstract Preview: Purpose: Using mixed fractionation schemes is a common technique in treating CNS lesions. This article describes an innovative plan-and-split approach for more efficient planning on the ZAP-X and thus...

Online Active Learning Strategies for Global Medical Physics Education: A Scoping Review

Authors: Mary Gronberg, Kelly Kisling, Ana Maria Marques da Silva

Affiliation: University of California, San Diego, The University of Texas Southwestern Medical Center, Pontifical Catholic University of Rio Grande do Sul

Abstract Preview: Purpose: To evaluate the current status of online teaching in medical physics and identify effective active learning strategies for global medical physics education.
Methods: A scoping review was c...

Optimizing Dose Coverage and Mitigating Electron Return Effects and Electron Stream Effects in MR-Linac Treatment of Extremity Malignancies: The Impact of Bolus and Gel Use

Authors: Kin Yin Cheung, Chen-Yu Huang, Chi Wah Kong, Ka Ki Lau, Pei-Xiong Li, Darren M. C. Poon, Bin Yang, Siu Ki Yu, Jing Yuan, Chi To Yung, Shang Peng Felix Yung

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital, Research Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study investigates optimal treatment strategies utilizing MR-linac for extremity lesions, with a specific focus on a 0.6 cm deep lesion in the right palm. The magnetic field-induced dose...

Patient-Specific Orthogonal Projection Based Real-Time Volumetric X-Ray Imaging for Proton Therapy

Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University

Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...

Patient-Specific Quality Assurance in SBRT Treatments Using 3D Polymer Gel Dosimetry

Authors: Esteban Arzaga-Barajas, Paola Jazmin Guadarrama Huerta, Jose Alejandro Jimenez, Guerda Massillon-JL, Maria Adela Poitevin-Chacón, Alejandro Rodriguez-Laguna

Affiliation: UNAM, Medica Sur

Abstract Preview: Purpose: To perform patient-specific quality assurance (PSQA) tests for four SBRT treatments of patients diagnosed with vertebral, ilium, pelvic lymph node and lung tumors.
Methods: MAGIC gel consi...

Performance Evaluation of CT-Based Lung Tumor Classification Deep Learning Algorithms Under Centralized and Federated Learning Frameworks

Authors: Yifei Hao, Chengliang Jin, Wenxuan Li, Bing Luo, Tao Peng, Yulu Wu, Fang-Fang Yin, Yue Yuan, Lei Zhang, Ruojun Zhou

Affiliation: School of Future Science and Engineering, Soochow University, Electrical and Computer Engineering Graduate Program, Duke Kunshan University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: Federated learning is a patient privacy-protecting technique that has recently been applied in the medical field. This study aims to evaluate the performance of several deep learning networks...

Performance Evaluation of an Upright, Short-Scan, Cone-Beam, Dedicated Breast CT System.

Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu

Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center

Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...

Personalized Anisotropic Margin Strategy for Cervical Cancer Online Adaptive Radiation Therapy

Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang

Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital

Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...

Phantom-Based Dosimetric Comparison of Multiple CT Metal Artifact Reduction Algorithms for Head-and-Neck Radiotherapy

Authors: Loren Bell, Charles S Cathcart, Brett William Eckroate, Harold Y Hu, Joshua Kilian-Meneghin, Ke Nie, Fredrick Warburton, Zhenyu Xiong, Keying (Karen) Xu, Ning J. Yue, Yin Zhang, Lili Zhou

Affiliation: RWJBarnabas Health, Basis Scottsdale, Rutgers Cancer Institute of New Jersey

Abstract Preview: Purpose: This study compares the dosimetric impact of multiple metal artifact reduction (MAR) algorithms from different CT simulator vendors using an anthropomorphic head phantom for head-and-neck (H/...

Preclinical Dosimetric Evaluation for Small Animal Study to Investigate Normal Tissue-Sparing Effects in the Electron Ultra-High Dose-Rate (FLASH) Environment

Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...

Presenting a Novel Treatment Scheme for Debulking Unresectable Large Tumors: Feasibility, Safety and Patient Reported Early Clinical Outcomes of SBRT Immediately Post-Spatially Fractionated Radiotherapy Delivery

Authors: James Knight II, Joshua Misa, Damodar Pokhrel, William St Clair, Eddy S Yang

Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine

Abstract Preview: Purpose: Highly-heterogenous sieve-like dose distribution via SFRT to large/bulky tumors (≄6 cm) could enhance tumor cell-death via both direct/indirect cell-kill mechanisms. Adding highly-conformal S...

Radiomics Changes in MR Images of Prostate and Dominant Intra-Prostate Lesions during SBRT on MR-Linac

Authors: David L. Barbee, David Byun, Ting Chen, Paulina E. Galavis, Siming Lu, Sarah Rosemary Morris, Hesheng Wang, Michael J Zelefsky

Affiliation: NYU Langone Health

Abstract Preview: Purpose: MR-Linac enables dose escalation in prostate SBRT on accurately defined dominant intra-prostate lesion (DIL) on daily MR images. This study aims to evaluate inter-fraction changes in the radi...

Real Time Monte Carlo Dose Calculation for Clinical Cyberknife Radiation Therapy Based on Deep Learning Diffusion Model

Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang

Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University

Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...

Real-Time 3D Dose Verification for MR-Guided Online Adaptive Radiotherapy (ART) Via Geometry-Encoded Deep Learning Framework

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...

Real-Time Proton and Carbon Ion Monte Carlo Dose Calculation through GPU-Acceleration and DL-Based Denoising Algorithms

Authors: Yankui Chang, Shijun Li, Xi Pei, Ripeng Wang, Xuanhe Wang, X. George Xu, Qing Zhang, Jingfang Zhao

Affiliation: University of Science and Technology of China, Shanghai proton and heavy ion center, School of Nuclear Science and Technology, University of Science and Technology of China, Anhui Wisdom Technology Co., Ltd.

Abstract Preview: Purpose:
This paper describes disruptive methods using both GPU-based MC simulation and deep-learning (DL)-based MC denoising algorithms, as well as clinical tests involving more than 560 patient p...

Region-Specific Structure-Function Coupling Alterations in Parkinson’s Disease: Insights from Multi-Modal MRI

Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu

Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinson’s disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...

Reproducibility of Target Position during Surface-Guided Breath-Hold Adaptive SBRT of Liver Cancer

Authors: Lili Chen, Xiaoming Chen, Chang Ming Charlie Ma, Joshua Meyer

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose: Fast CBCT (HyperSight) acquisition technique together with a surface-guided breath-hold (SGBH) would allow a better image quality for accurate target/organ delineation. It facilitates breath-...

Simultaneous Motion Estimation and Image Reconstruction with Spatiotemporal Implicit Neural Representation Initial (STINR-SMEIR) for Gas Bubble Motion Artifact Reduction in on-Board CBCT Imaging

Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...

Skin Lesion Subtype Classification Using Lesion and Border Radiomic Features

Authors: Rituparna Basak, Maede Boroji, Renee F Cattell, Vahid Danesh, Imin Kao, Kartik Mani, Xin Qian, Samuel Ryu, Tiezhi Zhang

Affiliation: Stony Brook Medicine, Stony Brook University, Washington University in St. Louis, Stony Brook University Hospital

Abstract Preview: Purpose: Fundamental qualitative characteristics physicians use to differentiate skin lesion subtypes include asymmetry, border irregularity, and color. Radiomic features have potential to quantify th...

Synthetic CT Generation from a Cycle Diffusion Model Based Framework for Ultrasound-Based Prostate HDR Brachytherapy

Authors: Michael Baine, Charles Enke, Yang Lei, Yu Lei, Ruirui Liu, Su-Min Zhou

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center, Department of Radiation Oncology, University of Nebraska Medical Center

Abstract Preview: Purpose: This study presents a framework for generating synthetic CT images using a Cycle Diffusion model, which can be utilized to enhance needle conspicuity in ultrasound-guided prostate HDR brachyt...

Synthetic Vs. Conventional Planar Imaging: Performance and Clinical Feasibility

Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman

Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University

Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...

Technique Factors Optimization and Radiation Dosimetry of an Upright, Short-Scan, Cone-Beam, Dedicated Breast CT System

Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu

Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center

Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...

The Development of Large Field MR Guided Radiotherapy for Pelvic Lymph Node SBRT and Its Dosimetry Improvement

Authors: David Byun, Ting Chen, Paulina E. Galavis, Allison McCarthy, Hesheng Wang, Michael J Zelefsky

Affiliation: NYU Langone Health

Abstract Preview: Purpose: To summarize a MR guided adaptive workflow developed for pelvic lymph nodes (PLN) stereotactic radiotherapy using large field size on Elekta Unity© MR Linac system, and to quantitatively anal...

The Feasibility of Ethos-Based Pulsed Reduced Dose-Rate (PRDR) Radiotherapy

Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su

Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)

Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...

The Root Cause of Large Differences in Calculated Beam Monitor Units between a Treatment Planning System and a QA Software

Authors: George X. Ding, Kenneth L. Homann

Affiliation: Vanderbilt University Medical Center

Abstract Preview: Purpose: It is standard practice that the beam monitor units (MUs) calculated by a commercial treatment planning system (TPS) is verified by a secondary dose calculation (SDC) software that independen...

Time and Energy-Encoded CT Reconstruction

Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: Conventional computed tomography (CT) measures the collective attenuation of primary photon fluence and then reconstructs the 3D images without using the timing information of individual phot...

Towards AI-Driven Adaptive Radiotherapy: Developing a Framework for Utilizing Large-Vision Models in Head-and-Neck Cancer Treatment.

Authors: Anthony J. Doemer, Bing Luo, Benjamin Movsas, Humza Nusrat, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia

Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health

Abstract Preview: Purpose: Large-vision models (LVMs) are rapidly emerging, yet their application in radiation oncology remains largely unexplored. This study investigates the potential of LVMs for offline adaptive rad...

Treatment Machine Matching for ELM in Eclipse v18.0 By Adjusting Physical Leaf Gap

Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk

Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center

Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...

Ultra-Sparse-View Cone-Beam CT Reconstruction Based Strictly-Structure-Preserved Deep Neural Network in Image-Guided Radiation Therapy

Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang

Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University

Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...

Understanding the Impact of Radiation on the Immune System and Its Clinical Implications Through Computational Modeling

Authors: Shu (Stella) Xing

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: N/A...

Unlocking Adaptive Radiotherapy Flexibility: Integrating Ethos Adaptive Therapy and Halcyon IGRT with Scripting Innovations

Authors: Min Geon Choi, Sean J. Domal, Ruiqi Li, Taoran Li, Mu-Han Lin, Yang Kyun Park, David D.M. Parsons, Justin D. Visak

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, University of Pennsylvania, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Ethos X-ray-guided online adaptive radiotherapy (ART) enables precise, daily adaptive treatments but requires significant resources, limiting widespread adoption. Many treatment sites do not ...

Utilization of Log File Analysis to Determine Deliverability of VMAT Plans As a Function of Plan Complexity

Authors: Jameson T. Baker, Sean T Grace, Cindy Pham, Michael A. Trager

Affiliation: Northwell

Abstract Preview: Purpose:
In VMAT planning, increasing complexity in MLC motion and modulation may improve dose distributions and OAR sparing while maintaining PTV coverage. However, increasing complexity can creat...

Weakly Supervised Spatial Implicit Neural Representation Learning for 3D MRI-Ultrasound Deformable Image Registration in HDR Prostate Brachytherapy

Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang

Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center

Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...