Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
MRI images with minimal artefacts to scan spine with Titanium instrumentation (screws, stabilizing rods, and spacer) are acquired by optimizing scanning parameters of pulse sequences (main...
Authors: Arash Bedayat, Jason Bradfield, Minsong Cao, Robert K Chin, Huiming Dong, J Paul Finn, Fei Han, Justin Hayase, Shu-Fu Shih, Xiaodong Zhong
Affiliation: Cardiac Electrophysiology, University of California, Los Angeles, Department of Radiation Oncology, University of California, Los Angeles, Department of Radiology, University of California, Los Angeles, Siemens Healthineers
Abstract Preview: Purpose: Cardiac SBRT is a promising treatment for ventricular tachycardia (VT). Success depends on accurate target delineation, for which 2D narrowband late gadolinium-enhanced (LGE) MRI offers valua...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Bohong Huang, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Four-dimensional cone-beam computed tomography (4D-CBCT) is critical in image-guided radiotherapy (IGRT) for visualizing tumor motion. However, sparse projection sampling often introduces sev...
Authors: Jeremy S. Bredfeldt, Cindy I. Hancox, Arianna Liles, Alex Marques, Usha Tedrow
Affiliation: Department of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School
Abstract Preview: Purpose: Ventricular tachycardia (VT) can be treated using cardiac radioablation. 4DCT simulation is commonly used, however, contrast injection timing is challenging. This study aimed to develop a pro...
Authors: Ryan Andosca, Rojine T. Ariani, Peter Boyle, Minji Victoria Kim, Michael Vincent Lauria, Daniel A. Low, Claudia R. Miller, Drew Moghanaki, Louise Naumann, Dylan P. O'Connell, Ricky R Savjani
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, Los Angeles, UCLA Radiation Oncology
Abstract Preview: Purpose: To demonstrate that 5DCT can provide an accurate internal tumor volume (ITV) while 4DCT cannot.
Methods: The 5DCT imaging protocol uses a motion model and 25 deformably registered free-bre...
Authors: Mohamed Eldib, Adam Mahl, Moyed Miften, Rachel Petragallo, Kelly L. Stuhr
Affiliation: University of Colorado - Anschutz Medical Campus, University of Colorado School of Medicine, University of Colorado Denver, Department of Radiation Oncology, University of Colorado
Abstract Preview: Purpose: To compare electron beam dose calculations performed manually with those computed using the Macro Monte Carlo simulation for standard fields on both phantom and patient setups, with the aim o...
Authors: Jamie s Baker, Sam Beddar, Mahsa Dehghanpour, Ariel MT Hoang, Emma Holliday, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Josie S Ruzek, Gabriel O. Sawakuchi
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, niversity of Texas MD Anderson Cancer Center School of Health Professions, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center School of Health Professions
Abstract Preview: Purpose: This study aims to evaluate the dosimetric impact on organs at risk (OAR) of small versus large spot sizes when treating pelvic cancer patients with pencil beam scanning (PBS) proton therapy....
Authors: Mubasheer Chombakkadath, Tara E. Tyson, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, University at Buffalo (SUNY)
Abstract Preview: Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART). Existing DIR phantoms either simulate tumor shape or volume changes but lack comprehensive motion simulati...
Authors: Yu Chang, Mei Chen
Affiliation: Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Abstract Preview: Purpose: Spot weights optimization, as a critical step in the proton therapy, is often time-consuming and labor-intensive. Deep learning, with its powerful learning and computational efficiency, can e...
Authors: Mitya M. Barreto, Nichole A. Harris
Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center
Abstract Preview: Purpose: To evaluate dosimeter dependence of measured AGD, and to develop a dosimeter independent method for evaluating the AGD, for CEDM exposures.
Methods: Three solid-state dosimeters (Raysafe-X...
Authors: Chin-Cheng Chen, Chia-Ho Hua, Christopher J. Kutyreff, Thomas E. Merchant
Affiliation: St. Jude Children's Research Hospital
Abstract Preview: Purpose: A dosimetric study was conducted to determine the optimal field parameters for a commercially available small-field applicator (SFA) used in spot-scanning proton stereotactic radiosurgery, pa...
Authors: Jie Deng, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Based on a 3D pre-treatment MRI scan, we developed DREME-MR to jointly reconstruct the reference patient anatomy and a data-driven, patient-specific cardiorespiratory motion model. Via a moti...
Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...
Authors: Benito De Celis Alonso, Braian Adair Maldonado Luna, Gerardo Uriel Perez Rojas, RenĂ© Eduardo RodrĂguez-PĂ©rez, Kamal Singhrao
Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla
Abstract Preview: Purpose: Artificial Intelligence (AI)-generated synthetic CT (sCT) images can be used to provide electron densities for dose calculation for online adaptive MRI-guided stereotactic body radiotherapy (...
Authors: Wenhua Cao, Xianjin Dai, PhD, Hadis Moazami Goudarzi, Gino Lim, Miaolan Xie, Lei Xing, Lewei Zhao
Affiliation: University of Chicago Booth School of Business, Department of Radiation Oncology, Stanford University, Department of Industrial Engineering, University of Houston, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) delivers a continuous dose of radiation during gantry rotation. 4Ï is a non-coplanar technique used for advanced proton therapy delivery. This work proposes a hybrid ...
Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2Dâ3D deformable registration addresses this problem by estimating LA-CBCTs from defor...
Authors: Tina Ehtiati, Grace Jianan Gang, Limei Ma, Oleg Shekhtman, Visish M. Srinivasan
Affiliation: Siemens Medical Solutions USA, Inc., University of Pennsylvania
Abstract Preview: Purpose: Saccular aneurysms are the most common type of intracranial aneurysm and are typically treated by endovascular embolization. The procedure requires approximately orthogonal fluoroscopy images...
Authors: Chloe Doen Kim, Patricia E. Lindsay, Bern Norrlinger, Jan P. Seuntjens
Affiliation: Princess Margaret Cancer Centre & University of Toronto, Queen's University, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To propose a method to check the consistency of VMAT delivery on linear accelerator (LINAC) with a commercial three-dimensional array device. The method is insensitive to the correction facto...
Authors: Eric Chang, Nguyen Phuong Dang, Andrew Lim, Lauren Lukas, Lijun Ma, Yutaka Natsuaki, Zhengzheng Xu, Hualin Zhang
Affiliation: Radiation Oncology, Keck School of Medicine of USC
Abstract Preview: Purpose: Harnessed the power of AI and Deep Learning (DL), Generalized Neural Network models for medical image transformation are trained to predict target images from reference images, often requirin...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: This study investigated cardiac motion characteristics of ventricular tachycardia patients to support patient-specific motion management for stereotactic arrhythmia radiotherapy (STAR) treatm...
Authors: Sung Woon Choi, Dong Wook Kim, Jin Sung Kim, Na Hye Kwon, Paulo Jorge Ribeiro Da Fonte
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Coimbra Institute of Engineering, Polytechnic University of Coimbra
Abstract Preview: Purpose: In hadrontherapy, such as proton and carbon ion therapy, it is desirable, for quality assurance reasons, to have an online beam energy measurement independent from the machine parameters. Sin...
Authors: Hongyu An, Phillip Cuculich, H Michael Gach, Yao Hao, Trevor McKeown, Clifford Robinson, Yuhao Wang, Deshan Yang
Affiliation: Washington University School of Medicine in St. Louis, Washington University School of Medicine, Duke University, Department of Radiation Oncology, Duke University, Washington University in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: Cardiorespiratory motion management is crucial in stereotactic arrhythmia radiotherapy to define target margins and minimize cardiac toxicity. While respiratory 4DCT (r4DCT) images can infer ...
Authors: Zhitao Dai, Riao Dao, Xuanfeng Ding, Qingkun Fan, Yajun Jia, Gang Liu, Gang Peng, Yujia Qian, Hong Quan, Kunyu Yang, Sheng Zhang, Lewei Zhao
Affiliation: Department of Radiation Oncology, Stanford University, Corewellhealth William Beaumont University Hospital, School of Mathematics and Statistics, Wuhan University, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Chinese Academy of Medical Sciences Cancer Hospital Shenzhen Hospital, School of Physics and Technology,Wuhan University, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen HospitalïŒ Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: Lattice radiation therapy (LRT) is an innovative three-dimensional(3D) implementation type of spatially fractionated radiation therapy (SFRT). This study aims to develop a novel spot-scanning...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Dual-energy imaging offers benefits, including metal artifact reductions (MAR) and improved contrast, that enhance visualization. Currently, dual-energy imaging is largely limited to CT scann...
Authors: Weiguo Lu, Hua-Chieh Shao, Guoping Xu, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Neural network-based lesion segmentation remains a significant challenge due to the low contrast between lesions and surrounding tissues (high ambiguity) and the variability of lesion shap...
Authors: Hao Gao, Yuting Lin, Nimita Shinde, Weijie Zhang
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: LATTICE, a form of spatially fractionated radiation therapy (SFRT), delivers high-dose peaks and low-dose valleys to the target volume and has been clinically used for large target volumes. H...
Authors: Hao Gao, Wangyao Li, Yuting Lin, Chao Wang, Wei Wu
Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Proton minibeam radiation therapy (pMBRT) delivers a unique peak-and-valley dose pattern using collimators with narrow slits, offering improved normal tissue sparing compared to conventional ...
Authors: Charmainne Cruje, Maria Dumol, Nawroz Fatima, Marisa Finlay, Kalaina Johnson, Raman Mohla, Jasleen Uppal
Affiliation: Trillium Health Partners, Carlo Fidani Regional Cancer Centre
Abstract Preview: Purpose: To evaluate the robustness of a breast SBRT protocol in achieving target coverage by utilizing online- and retrospectively-matched CBCT-to-CT images.
Methods: The first pilot patient was s...
Authors: Courtney R. Buckey, Jay W. Burmeister, Minsong Cao, Grace Chang, Yu Kuang, Yixiang Liao, Yi Rong, Dandan Zheng
Affiliation: Mayo Clinic, Mayo Clinic Arizona, Karmanos Cancer Center, Gershenson ROC, Wayne State University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, Medical Physics Program, University of Nevada, Rush University Medical Center, University of Rochester
Abstract Preview: Purpose: Investigate the adequacy of training for therapeutic medical physics residents in select special procedures.
Methods: After a review of existing literature, a multi-institutional group dev...
Authors: Zhenzhen Dai, Anthony J. Doemer, Ryan Hall, Kenneth Levin, Bing Luo, Benjamin Movsas, Karen C. Snyder, Kundan S Thind, Eleanor Walker
Affiliation: Henry Ford Health, HFHS
Abstract Preview: Purpose: To investigate the feasibility of a predictive tool for efficient allocation of hypofractionated whole-breast irradiation patients between Varian Truebeam and Ethos systems.
Methods: A ful...
Authors: Jaryd Ricardo Christie, Anthony J. Doemer, William T. Hrinivich, Junghoon Lee, Calin Reamy, Kundan S Thind
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, Henry Ford Health
Abstract Preview: Purpose: To develop and validate an open-source Python package for fast, widely compatible, and user-friendly photon dose calculation algorithm through comparisons with clinical treatment planning sys...
Authors: Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Joseph Shields, Christopher Tyerech
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, Department of Radiation Oncology, University of Pennsylvania, UPMC
Abstract Preview: Purpose: HyperSight is a new platform for image-guided radiation therapy, offering advanced reconstruction algorithms, a large field-of-view, and rapid acquisition times. To validate the performance o...
Authors: Yongrui Bai, Xuming Chen, Yong Liu, Xiumei Ma
Affiliation: Department of Radiation Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Department of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Abstract Preview: Purpose: Hematologic toxicity (HT) is a common complication in patients with cervical or endometrial cancer. This study aims to develop a precise predictive model for acute HT in patients with cervica...
Authors: Liu Hong, Wen C. Hsi, Faraz Kalantari, Romy Megahed, Ganesh Narayanasamy, Maida Ranjbar, Pouya Sabouri, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: Quantitative apparent diffusion coefficients (ADC) in diffusion-weighted MRI (dMRI) reflect water diffusivity and thus provide tissue cellular density information. Functional diffusion mappin...
Authors: Ioannis Androulakis, Miranda E.M.C. Christianen, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Lorne Luthart, Remi A. Nout, Henrike Westerveld
Affiliation: Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
Despite the advantages of transrectal ultrasound-based treatment planning for HDR prostate cancer brachytherapy which allows on-line treatment delivery in the intraoperative setting, it is...
Authors: Paul L. Carson, Sander Dekker, Stephen Z Pinter, Megan K. Russ
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Michigan, Cablon Medical B.V., Univ of Michigan, Dept. of Radiology
Abstract Preview: Purpose:
To promote a simplified, inexpensive, but rigorous set of ultrasound QA tests and to evaluate their potential using a Randomly-placed very Hypoechoic Sphere Phantom (RHSP) in comparison to...
Authors: Xiangli Cui, Man Hu, Wanli Huo, Da Yao, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
To study the fine-tuning strategy of pre-trained AI image generation model to adapt to the generation of small sample meningioma MRI images, explore its impact on observer performance, and...
Authors: Neil A. Kirby, Parker New, Niko Papanikolaou, Holly Paschal, Karl H. Rasmussen, Daniel L. Saenz
Affiliation: UT Health San Antonio
Abstract Preview: Purpose: To simplify the traditional method of patient-specific skin collimation and improve the precision of electron radiotherapy treatment with a new surface conforming collimation system.
Metho...
Authors: David Brizel, Kyle J. Lafata, Jian-Guo Liu, Yvonne M Mowery, Yvonne M Mowery, William Paul Segars, Jack B Stevens
Affiliation: Department of Physics, Duke University, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To develop a technique to quantify tumor topology using a unifying mathematical framework that integrates texture and morphology and to evaluate its feasibility as a prognostic biomarker for ...
Authors: Penghao Gao, Zejun Jiang
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...
Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu
Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...
Authors: Walaa Abdelfadeel, Reagan Thomas Dugan, Tiffany Kinsey, Cameron Kofler, Zheng Feng Lu, Ingrid S. Reiser, Gregory Stacy, Sara Wallace
Affiliation: University of Chicago Medicine, University of Chicago
Abstract Preview: Purpose: To develop an accurate, vendor-neutral method for estimating geometric magnification at the plane of the hip joint on standing anterior-posterior (AP) radiographs for digital templating of to...
Authors: Hilary P Bagshaw, Mark K Buyyounouski, Cynthia Fu-Yu Chuang, Yu Gao, Dimitre Hristov, Lianli Liu, Lawrie Skinner, Lei Xing
Affiliation: Department of Radiation Oncology, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
MR-guided radiation therapy has introduced a significant leap in cancer treatment by allowing adaptive treatment. The low-field MR-guided system predominantly uses the TrueFISP sequence, w...
Authors: Larry A. DeWerd, Sean Jollota, Karen Rex Pius Vincent
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison
Abstract Preview: Purpose: Absolute measurements, often used to establish primary standards, offer lower measurement uncertainty. For 192Ir high-dose-rate (HDR) brachytherapy, the interim primary standard for air-kerma...
Authors: Xiu tong Lin, Tao Sun
Affiliation: Department of Radiation physics and technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the positioning accuracy and time efficiency of "Sphere-Mask" Optical Positioning System (OPS) and traditional laser light positioning method in breast cancer radiotherapy, and to ...
Authors: Emi Ai Eastman, Chao Guo, Christina Lee, Xinhua Li, Alexander W. Scott, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
Smoking is one of the risk factors for coronary artery disease. It is desirable to estimate the coronary artery calcification (CAC), a key biomarker for atherosclerosis and cardiovascular ...
Authors: Zachary Diamond, Pretesh Patel, Sibo Tian, Xiaofeng Yang, David Yu, Ahmal Jawad Zafar, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose:
We propose a method to optimize adaptive proton FLASH therapy (ADP-FLASH) using modularized pin-ridge filters (pRFs) by recycling module pins from the initial plan, reducing pRF adjustment...
Authors: Amir Abdollahi, Oliver JĂ€kel, Maxmillian Knoll, Rakshana Murugan, Adithya Raman, Patrick Salome
Affiliation: UKHD & DKFZ, Department of Medical Physics in Radiation Oncology, German Cancer Research Center (DKFZ), German Cancer Research Centre(DKFZ), DKFZ, MGH
Abstract Preview: Purpose:
Missing MRI sequences, due to technical issues in data handling or clinical constraints like contrast agent intolerance, limit the use of medical imaging datasets in computational analysis...
Authors: Denis Bergeron, Ryan P Fitzgerald, Ravneet Kaur, Rao Khan
Affiliation: John Hopkins University, NIST Radiation Physics Division, Howard University, National Institute of Standards and Technology
Abstract Preview: Purpose: There is growing interest in short-lived alpha-emitting radionuclides for cancer therapy due to their ability to selectively target and destroy cancer cells while sparing healthy tissue. Howe...
Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa
Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health
Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Richard L.J. Qiu, Mojtaba Safari, Shansong Wang, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: MRI offers excellent soft tissue contrast for diagnosis and treatment but suffers from long acquisition times, causing patient discomfort and motion artifacts. To accelerate MRI, supervised d...
Authors: Ioannis Androulakis, Jérémy Godart, Mischa Hoogeman, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Robin Straathof, Henrike Westerveld, Myra van Laar
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
In brachytherapy for gynaecological cancers using intracavitary applicators, implant reconstruction is commonly performed using applicator libraries. These libraries contain applicator geo...
Authors: Mohamed Bahaaeldin Mohamed Afifi, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Fox Chase Cancer Center, Radiological Sciences and Medical Imaging Department, College of Applied Medical Sciences, Prince Sattam bin Abdulaziz University.
Abstract Preview: Purpose: Reirradiation of recurrent cancer or a newly developed lesion in a proximal location poses a challenge for radiation treatments. This is occasionally encountered in many modern clinics and ef...
Authors: Jie Hu, Zhengdong Jiang, Nan Li, Tie Lv, Yuqing Xia, Shouping Xu, Gaolong Zhang, Wei Zhao, Changyou Zhong
Affiliation: School of Physics, Beihang University, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Radiotherapy Department of Meizhou Peopleâs Hospital (Huangtang Hospital), UT Health San Antonio, National Cancer Center/ National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, PeopleÊŒs Republic of China, Department of Radiation Oncology
Abstract Preview: Purpose: Patients usually undergo cone-beam computed tomography (CBCT) scans which are used for patient set-up before radiotherapy. However, the low image quality of CBCT hinders its use in adaptive r...
Authors: Harsh Arya, Yan Chang, Yujie Chi, Varghese Anto Chirayath, Joshua Rajan, Pan Zui
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: In targeted alpha therapy (TAT), absorbed dose rates can vary significantly spatially and temporally, impacting therapeutic efficacy as well as carcinogenic potential. This study reports the ...
Authors: Cheewai Cheng, Indra J. Das, Jeffrey Yui Hei Wong, Poonam Yadav
Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine
Abstract Preview: Purpose: Radiation treatment machine replacement brings chaos and urgency of timely completion of machine commissioning for every procedure used including TBI that are time consuming. Based on past ex...
Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose: Curation remains a significant barrier to the use of âbig dataâ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...
Authors: Lili Chen, Ahmed A. Eldib, Chang Ming Charlie Ma
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Specialized adaptive radiotherapy (ART) systems have been developed and clinically implemented, which are either cost-ineffective such as MR-linacs or inflexible in workflow such as the Ethos...
Authors: Jameson T. Baker, Yijian Cao, Jenghwa Chang, Sean T Grace, Lyu Huang, Jian Liu, Echezona Simon Obi, Anurag Sharma
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
To validate the end-to-end dosimetrical accuracy of Varian HyperSight CBCT for adaptive radiotherapy (ART), from simulation to dose delivery, using radiochromic film dosimetry in a Rando p...
Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...
Authors: Hao Gao, Xue Hong, Harold Li, Yuting Lin, Jufri Setianegara, Xin Tong, Chao Wang, Weijie Zhang, Ya-Nan Zhu
Affiliation: Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Lattice radiotherapy (LATTICE) is a form of spatially fractionated radiation therapy (SFRT) designed to deliver high radiation doses to specific tumor regions (vertices) while sparing surroun...
Authors: Debora de Souza Antonio, Romy Guthier, Konrad Pawel Nesteruk, Erno Sajo, William Paul Segars, Gregory C. Sharp, Atchar Sudhyadhom, Hengyong Yu
Affiliation: Massachusetts General Hospital, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Massachusetts General Hospital and Harvard Medical School, University of Massachusetts Lowell
Abstract Preview: Purpose: To develop an open-access toolkit for rapidly generating simultaneously realistic CT scans and low-field MR images of the abdominal region, based on patient data, while employing an XCAT phan...
Authors: Daming LI, Jinsen Xie, Zhe Zhang
Affiliation: Peking University Shenzhen Hospital Radiotherapy Department, School of Nuclear Science and Technology, University of South China
Abstract Preview: Purpose:
This study aims to investigate the feasibility of online dose measurement of the Trilogy linear accelerator output based on target current pulse signals.
Methods:
A data acquisition ...
Authors: Javier Chiasson, Dominique Guillet, Arthur Lalonde, Karim Zerouali
Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal
Abstract Preview: Purpose:
To validate a Monte Carlo (MC) model of a Ultra-High dose rate (UHDR) electron beam using a prototype flashdiamond (fD) detector coupled to an electrostatically shielded beam current trans...
Authors: Mylinh Dang, Laila A Gharzai, Xinlei Mi, Poonam Yadav
Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine
Abstract Preview: Purpose: Delineation of organs at risk (OAR) in the head/neck region requires substantial physician time. Many artificial intelligence (AI) based auto-contouring software are commercially available. T...
Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...
Authors: Xinhua Li, Vu Nguyen, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose: Assessing iodine concentration in liver lesions is essential for evaluating contrast enhancement in multi-phase liver CT and for accurate disease diagnosis. This study aims to evaluate the as...
Authors: Gary Y. Ge, Azmul Siddique, Jie Zhang
Affiliation: Department of Radiology, University of Kentucky, University of Kentucky
Abstract Preview: Purpose: Virtual grid technology addresses scattered radiation without a physical grid, offering the potential to reduce patient radiation dose while maintaining image quality. However, this potential...
Authors: Srinivas Cheenu Kappadath, James Long, Armeen Mahvash, Anna Marks, Ajalaya Teyateeti
Affiliation: Mahidol University, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose:
Alpha-fetoprotein (AFP) has been implicated as prognostic factor of overall survival (OS) for hepatocellular carcinoma (HCC). We present a statistical approach to determine optimal AFP-cut...
Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan
Affiliation: University of Florida
Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: The response of healthy vasculature due to radiation treatments is an underexplored area of radiation oncology. Understanding the impact of radiation on veins could advance treatment optimiza...
Authors: David Alejandro Collazos Burbano, Antonio Adilton Oliveira Carneiro, Paul L. Carson, Jose Eduardo Freire, Theo Zeferino Pavan, Joao Henrique Uliana, Nicholas Zufelato
Affiliation: University of SĂŁo Paulo, University of Michigan, University of Sao Paulo
Abstract Preview: Purpose: Develop a theranostic platform that integrates magnetic hyperthermia (MH), ultrasound, and magnetic nanoparticles (MNPs) to improve diagnosis, treatment, and monitoring of hyperthermia proced...
Authors: Mehdi Amini, Minerva Becker, Simina Chiriac, Alexandre Cusin, Dimitrios Daskalou, Ghasem Hajianfar, Sophie Neveu, Marcella Pucci, Yazdan Salimi, Pascal Senn, Habib Zaidi
Affiliation: Geneva University Hospital, Division of Radiology, Diagnostic Department, Geneva University Hospitals, Service of Otorhinolaryngology-Head and Neck Surgery, Department of Clinical Neurosciences, Geneva University Hospitals
Abstract Preview: Purpose: Personalized prediction of vestibular schwannoma (VS) tumour growth is crucial for guiding patient management decisions toward observation versus intervention. This study proposes an automate...
Authors: Austin Castelo, Xinru Chen, Caroline Chung, Laurence Edward Court, Jaganathan A Parameshwaran, Zhan Xu, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
To develop a deep learning-based segmentation model to automatically delineate tumors from full-body PET/CT images.
Methods:
PET/CT image pairs of 91 patients were collected for this...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Zahra Ahmadi Ganjeh, Stefan Both, Peter Dendooven, Jeffrey Free, Brian Zapien Campos
Affiliation: Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Particle Therapy Research Center (PARTREC), Department of Radiation Oncology, University Medical Center Groningen, University of Groningen
Abstract Preview: Purpose: Positron emission tomography (PET) has been investigated for range monitoring in intensity-modulated proton therapy (IMPT), but real-time feedback been limited due to the focus on long-lived ...
Authors: Paul Boisseau, Eric S. Diffenderfer, Andrew Friberg, Wenbo Gu, Matthew Nichols, Kan Ota, Xiaokun Teng, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Pyramid Technical Consultants, Inc., University of Pennsylvania
Abstract Preview: Purpose: Traditional quality assurance procedures for proton pencil beam energies involve water tank setups or multiple solid water phantoms and are time-consuming. This study demonstrates that an inn...
Authors: Scott James Bright, Vered Domankevich-Bachar, Mandira Manandhar, Poliana Marinello, Yogesh Rai, Marco Freitas Reis, Alexandre Rubinstein, Gabriel O. Sawakuchi, Ronen Segal, Walison Augusto Silva Brito, Mark Wasley, Amy Wu
Affiliation: MD Anderson Cancer Center, Alpha Tau Medical Ltd, Alpha Tau Medical LTD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Immunologically cold breast cancers are aggressive and difficult to treat due to their lack of immune cell infiltration. The combination of high-LET radiation with DNA repair inhibitors offer...
Authors: Evan Calabrese, Hangjie Ji, Kyle J. Lafata, Casey Y. Lee, Eugene Vaios, Chunhao Wang, Lana Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Department of Radiation Oncology, Duke University, Duke Kunshan University, North Carolina State University
Abstract Preview: Purpose: To develop a biologically guided deep learning (DL) model for predicting brain metastasis(BM) local control outcomes following stereotactic radiosurgery (SRS). By integrating pre-SRS MR image...
Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University
Abstract Preview: Purpose: Multi-parametric MRI (mpMRI) is widely used for deep learning (DL)-based automatic segmentation of brain tumors. While multi-contrast images concatenated as channels are typically input to ne...
Authors: Ryan Clark, Anthony Magliari, Luis Felipe Oliveira E Silva, Yang Sheng, Jason R Vickress, Qingrong Jackie Wu, Giulianne Rivelli Rodrigues Zaratim
Affiliation: Verspeeten Family Cancer Center, Office of Medical Affairs, Varian, A Siemens Healthineers Company, Confiar Radioterapia, Duke University Medical Center
Abstract Preview: Purpose: Develop a toolset to replace several of the tedious steps required to manually generate 3D breast treatment plans using static gantry forward planned tangent beams.
Methods: Eclipse Sc...
Authors: Rachael Blair, Les Butler, Lillian Dickson, Kyungmin Ham, Charles Hartman, Kenneth (Kip) Matthews, Corinne Vanya
Affiliation: Louisiana State University, University of Minnesota, Refined Imaging LLC, Center for Advanced Microstructures and Devices
Abstract Preview: Purpose:
To develop and evaluate an x-ray interferometry system (XIS) for low-dose, high-sensitivity diagnostic imaging of lung diseases such as chronic obstructive pulmonary disease (COPD), asthma...
Authors: Martha J. Malin, Matthew Schelin
Affiliation: NYU Langone Health
Abstract Preview: Purpose: To evaluate the agreement between ExacTrac Dynamic (ETD) and CBCT-based positioning for spine SRS/SBRT treatments during initial patient setup and repositioning after intrafraction motion.
Authors: Luke Connell, Stephen F. Kry, Malcolm R. McEwen, Bryan R. Muir, James Renaud, Emil Schueler, Hayden Scott, Paige A. Taylor
Affiliation: National Research Council, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: To demonstrate the capability of a robust calorimeter to accurately determine the absorbed dose delivered by an electron FLASH beamline.
Methods: Electron FLASH beams of 6 MeV and 9 Me...
Authors: Kellin M De Jesus, Leon Dunn, Les Sztandera, David H. Thomas
Affiliation: IsoAnalytics Pty. Ltd., Thomas Jefferson University
Abstract Preview: Purpose: Machine accuracy and performance are critical for ensuring the safety and efficacy of intensity-modulated radiotherapy (IMRT and VMAT). This study aims to analyze a large and diverse set of l...
Authors: Mahmoud H Abdelgawad, Shahabeddin mostafanazhad Aslmarand, Lili Chen, Xiaoming Chen, Ahmed A. Eldib, Teh Lin, Chang Ming Charlie Ma, Robert A. Price
Affiliation: Physics department, Faculty of science, Al-Azhar University, Fox Chase Cancer Center
Abstract Preview: Purpose: Many modern radiotherapy clinics are moving to online adaptive radiotherapy. A recent upgrade of the CBCT-based adaptive radiotherapy system introduced ultra-high-speed image acquisition. Thi...
Authors: Simon Brundage, Jiajin Fan, Ulrich Langner, Qiongge Li, Jian Liu, Wei Nie, Edwin Quashie, Xiaofeng Zhu
Affiliation: Brown University Health, Hofstra University Medical Physics Program, Inova Hospital, Inova Schar Cancer Institute, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose:
Managing departmental policies, clinical protocols, QA procedures, workflows, and troubleshooting documentation is critical in radiation oncology. A Microsoft-based wiki platform was devel...
Authors: Mateb Ali Alghamwa, Haya Aljuaid, Siyong Kim, Tianjun Ma, William Song
Affiliation: Virginia Commonwealth University
Abstract Preview: Purpose: The integration of Plastic Scintillation Detectors (PSDs) into 0.35T MR-Linac systems represents a significant advancement in radiotherapy, offering substantial benefits due to their tissue-e...
Authors: Sen Bai, Guyu Dai, Dong Gao, Lecheng Jia, Guangjun Li, Yanfang Liu, Ying Song, Qing Xiao, Wei Zhang
Affiliation: United Imaging Healthcare, West China Hospital of Sichuan University, Shenzhen United Imaging Research Institute of Innovative Medical Equipment
Abstract Preview: Purpose:
Electronic portal imaging device (EPID) is currently the most widely used in-vivo dosimetry (IVD) device. However, the effective detector area shortage hinders further applications. This s...
Authors: Dominique Guillet, Arthur Lalonde, Bryan R. Muir, James Renaud, Karim Zerouali
Affiliation: Universite de Montreal, Centre Hospitalier de l'Universite de Montreal, National Research Council
Abstract Preview: Purpose:
To evaluate the dose rate dependence, beam quality dependence, and short-term stability of a novel flashDiamond (fD) prototype detector for conventional and ultra-high dose rate (UHDR) bea...
Authors: Lei Dong, Yin Gao, Taoran Li, Michael Salerno, Boon-Keng Kevin Teo, Melissa Vila
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: A novel solution, RapidArc Dynamic-RAD (Varian Medical Systems, Palo Alto, USA) has been implemented to integrate VMAT with modulation of IMRT-like static-angle ports, including use of a dyna...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Kaile Li, Esmail Parsai
Affiliation: Alexander T. Augusta Military Medical Center, Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To evaluate the sensitivity of the portal dosimetry system with the Arc CHECK system at identical Volumetric Modulated Arc Therapy (VMAT) setup
Methods: An Arc CHECK system from Sun Nuclea...
Authors: Colin Adam Doyle, Celeste Winters
Affiliation: Department of Diagnostic Radiology, Oregon Health & Science University, School of Medicine, Oregon Health & Science University
Abstract Preview: Purpose: To audit our radioactive iodine (I-131) dosimetry protocol, review dosimetry methods used at other facilities, investigate the clinical impact of I-131 dosimetry at our facility, and test the...
Authors: Dylan Yamabe Breitkreutz, Lee Chin, Brige P. Chugh, Mark D'Souza, Brian M. Keller, Anthony Kim, Michelle K. Nielsen, Arjun Sahgal
Affiliation: Sunnybrook Health Sciences Centre
Abstract Preview: Purpose: The Elekta Unity MR-linac delivers highly conformal SBRT treatments using IMRT. These treatment plans require patient-specific quality assurance (PSQA) measurements to detect discrepancies be...
Authors: David L. Barbee, Paulina E. Galavis, Lena Adel Samad, Jose R. Teruel Antolin
Affiliation: NYU, NYU Langone Health
Abstract Preview: Purpose: To validate an automated script that converts treatment plans of varying Varian MLC models
Methods: A C# script was developed using the Eclipse Scripting API to convert treatment plans...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: Prompt gamma (PG) imaging is a promising modality for proton dose verification. Currently, there is a lack of effective tool to investigate the PG emission during proton therapy and optimize ...
Authors: Alan H. Baydush, Sarah Cummings, Jeffrey Michael Fenoli, Christy Hickerson, Lalith Kumaraswamy, Philmo Oh, Sarah B. Wisnoskie
Affiliation: Novant Health Cancer Institute, Novant Health
Abstract Preview: Purpose: To develop, validate, and commission a VMAT Total Body Irradiation (TBI) workflow by integrating publicly available resources, commercial solutions, and in-house testing to enhance treatment ...
Authors: Shupeng Chen, Xiaoda Cong, Raymond Dalfsen, Rohan Deraniyagala, Xuanfeng Ding, James E. Dolan, Xiaoqiang Li, Jian Liang, Peilin Liu, An Qin, Martin Soukup, Craig Stevens, Xiangkun Xu, Weili Zheng
Affiliation: Corewell Health William Beaumont University Hospital, Corewellhealth William Beaumont University Hospital, William Beaumont University Hospital, Elekta, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Corewellhealth William Beaumont Hospital, Department of Radiation Oncology, Corewell Health William Beaumont University Hospital
Abstract Preview: Purpose: To facilitate clinical use of the proton feature of Monaco treatment planning system(TPS), we commissioned and validated it on a compact proton therapy system.
Methods: Pencil Beam Scannin...
Authors: Michalis Aristophanous, Steven Blum, Laura I. Cervino, Antonio L. Damato, Karen Episcopia, Chi Huang, Shih-Chi Lin, Michelle K. Savacool
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Varian Ethos (Varian Medical Systems, Palo Alto, CA) is a 6 MV flattening-filter-free (FFF) only machine, posing a challenge in creating homogeneous dose distributions when using manual 3D-CR...
Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed
Affiliation: University of Alabama at Birmingham
Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...
Authors: Serdar Charyyev, Cynthia Fu-Yu Chuang, Veng Jean Heng, Lianli Liu, Lei Xing, Yong Yang
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: To replace large finite-size photon phase space files with a compact neural network capable of generating an infinite number of particles.
Methods: Three separate models were developed to ...
Authors: Theodore Higgins Arsenault, Beatriz Guevara, Rojano Kashani, Raymond F. Muzic, Gisele Castro Pereira, Alex T. Price
Affiliation: University Hospitals Seidman Cancer Center, Case Western Reserve University Department of Biomedical Engineering
Abstract Preview: Purpose: Accurate dose prediction in radiotherapy is essential for treatment planning. This study evaluates four nnUnet-based models using the OpenKBP head and neck dataset: a baseline model (Model 1)...
Authors: Alan Rui Li, Qihui Lyu, Dan Ruan, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
The Sparse Primary Sampling (SPS) grid was shown in a previous computational study to improve image quality by correcting scatter-induced effects and artifacts in Cone-beam Computed Tomogr...
Authors: Minsong Cao, Amar Kishan, Yi Lao, An Liu, Beth Neilsen, X. Sharon Qi, Kun Qing, Ke Sheng, Michael Steinberg, Luca F Valle, Terence Williams
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, City of Hope Medical Center, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: To investigate the clinical relevance of planned versus delivered doses in toxicity associations utilizing localized assessment of genitourinary (GU) toxicity in bladder subregions among pros...
Authors: Wenwen Bai
Affiliation: The Fourth Hospital of Hebei Medical University
Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...
Authors: Aditya P. Apte, Joseph O. Deasy, Jue Jiang, Nancy Lee, Sudharsan Madhavan, Nishant Nadkarni, Lopamudra Nayak, Harini Veeraraghavan, Wei Zhao
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To track early response to radiotherapy using digital twins, it is crucial to quantify tumor volume and mass changes. Traditional tumor detection methods, particularly in image registration, ...
Authors: Jacinta E. Browne, Tzu Cheng Chao, Ajit Deveraj, Ece Ercan, Tim Leiner, Alessio Perazzolo, Michal Povazan, Jouke Smink, Camilla Vita, Spencer Waddle, Dinghui Wang
Affiliation: UniversitaÌ Cattolica del Sacro Cuore, Philips Healthcare, Mayo Clinic
Abstract Preview: Purpose:
In recent years, mid-field MRI has shown promise to meet the technical demands of cardiac imaging1. Mid-field strengths offer advantages to CMR due to shorter T1-relaxation times, lower sp...
Authors: Meghan Lubner, Krista McClure, Aria M. Salyapongse, Timothy P. Szczykutowicz, Giuseppe Toia, Ming Yan, Zhye Yin, Meghan Yue
Affiliation: GE HealthCare, Departments of Radiology and Medical Physics, University Wisconsin-Madison, GE Healthcare, University of Wisconsin-Madison, UW-Madison, University of Wisconsin Madison, Department of Radiology
Abstract Preview: Purpose: To evaluate virtual unenhanced (VUE) and true unenhanced (TUE) human subject images on a prototype deep silicon photon-counting detector (PCD) CT with prototype algorithms.
Methods: 5 subj...
Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...
Authors: Michael Confer, Mark A. Newpower
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A pediatric patient recently presented to our clinic for treatment for chordoma, which was near the brainstem. The clinician elected to treat this patient using intensity modulated proton the...
Authors: Junsheng Cao, Khushdeep Singh
Affiliation: Overlook Medical Center
Abstract Preview: Purpose: Eclipse v18 introduces Enhanced Leaf Modeling for MLCs. This study investigates the MLC off-axis characteristics using portal dosimetry
Methods:
MLC characteristics were analyzed for th...
Authors: Ivan M. Buzurovic, Phillip M. Devlin, Evangelia Kaza, Michael John Lavelle
Affiliation: Department of Radiation Oncology, Dana-Farber/Brigham and Womenâs Cancer Center, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Recent work in surface brachytherapy (SBT) has demonstrated the feasibility of using magnetic resonance (MR)-guidance in place of Computer Tomography (CT) in SBT planning. The purpose of this...
Authors: Tianyuan Dai, Zejun Jiang, Xiangyue Kong
Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
This study aims to evaluate the reliability of SFRT-VMAT plan verification by comparing two QA methods: Portal Dosimetry (PD) and Delta4Âź.
Methods:
Preteatment QA was conducted for 1...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis, Hamlet Spears
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study evaluates the range of motion of abdominal organs using 4D stack-of-stars magnetic resonance (MR) imaging and 4D computed tomography (CT), the current clinical standard. Accurate o...
Authors: Afrouz Ataei, Victor Moy, Mark P. Supanich
Affiliation: Rush University
Abstract Preview: Purpose: This study evaluates the impact of ultra-high resolution (UHR) mode on the visualization of small vessels in coronary computed tomography angiography (CTA) using a photon-counting CT scanner....
Authors: Junsheng Cao, Luis A. Maduro Bustos, Khushdeep Singh
Affiliation: Overlook Medical Center, Atlantic Health System at Morristown Medical Center
Abstract Preview: Purpose: To evaluate the agreement between the Sun Nuclear Multi-Met Winston Lutz test (WL) and Varianâs Machine Performance Check (MPC) in assessing isocenter alignment, couch, and collimator rotatio...
Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao
Affiliation: Duke University, Duke University Medical Center
Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...
Authors: Julien Forthomme, Carolina Llina Fuentes, Valentin Hamaide, Lucian Hotoiu, Rudi Labarbe, Rasmus Nilsson, Arnaud Pin, Francois Vander Stappen, Erik Traneus
Affiliation: RaySearch Laboratories AB, Ion Beam Applications SA
Abstract Preview: Purpose: Conformal FLASH achieves ultra-high-dose-rate (UHDR) proton therapy (>40 Gy/sec) by scanning a mono-energetic pencil beam through accessories (range shifter, Conformal Energy Modulator, apert...
Authors: Niki Fitousi, Anna Romanyukha, Stuart Utting
Affiliation: University Hospitals Dorset, Qaelum NV
Abstract Preview: Purpose:
For increased patient safety and with a focus on sustainability in the radiology department, efforts are being made to optimize contrast media usage. In this study, the possibility of util...
Authors: Min Cheol Han, Chae-Seon Hong, Changhwan Kim, Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, HO Lee, Kwangwoo Park, Ye-In Park, Junyoung Son
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Yongin Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Overresponse in surface in-vivo dosimetry using optically stimulated luminescence dosimeter (OSLD) depends on the beam incidence angle. This study aimed to investigate correction factors to d...
Authors: Seung Yeon Kim, Grant A. McAuley, Ju A Park, Jerry D Slater
Affiliation: Loma Linda University
Abstract Preview: Purpose: The production of proton minibeams in standard PBS nozzles is challenging due to the effects of finite source beam divergence and multiple Coulomb scattering. Herein we investigate the use of...
Authors: Afrouz Ataei, Xinhui Duan, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose:
Electron density (ED) phantoms are crucial for calibrating CT number (HU) to relative ED in treatment planning. This study evaluates the differences in HU-to-ED calibrations between two co...
Authors: Afrouz Ataei, Andrew R. Godley, Mi-Ae Park, Mahbubur Rahman, Liqiang Ren, Chenyang Shen, Gary Xu
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University, Imaging Services, UT Southwestern Medical Center
Abstract Preview: Purpose: Even though many patients undergo diagnostic CT scans prior to treatment, simulation CT scans are commonly required for treatment planning. This study evaluates whether prior diagnostic CT sc...
Authors: Yong Chen, Christina Henson, Yuchen Qiu, Marti Roper
Affiliation: University of Oklahoma HSC, University of Oklahoma Health Sciences Center, University of Oklahoma, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Traditionally, Head and Neck cancer patients have one or two treatment replans through their treatment course, which fails to account for anatomical changes in position, weight loss, or tumor...
Authors: Hector Andrade-Loarca, Ines Butz, Chiara Gianoli, Prof. Gitta Kutyniok, Jianfei Li, Katia Parodi, Prof. Vincenzo Patera, Angelo Schiavi, Prof. Ozan Ăktem
Affiliation: Sapienza University of Rome, Department of Mathematics, Royal Institute of Technology, School of Computation, Information and Technology, Technische Universitaet Muenchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Department of Mathematics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen
Abstract Preview: Purpose: To explore and demonstrate the feasibility of accurate and fast prediction of the water equivalent thickness (WET) distribution of tissue traversed by a proton imaging pencil beam, aiming at ...
Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham
Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona
Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...
Authors: Mark Bowers, Gabriel Carrizo, Jimmy Caudell, Vladimir Feygelman, Kevin Greco, Christian Hahn, Jihye Koo, Kujtim Latifi, Fredrik Lofman, Jacopo Parvizi, Muqeem Qayyum, Caleb Sawyer
Affiliation: RaySearch Laboratories, Moffitt Cancer Center
Abstract Preview: Purpose: Head and neck (H&N) radiotherapy planning is complex, with multiple competing objectives. We endeavored to improve efficiency of planning by developing a deep learning (DL) model trained to p...
Authors: Beth Bradshaw Ghavidel, Chih-Wei Chang, Yuan Gao, Priyanka Kapoor, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Jill Remick, Justin R. Roper, Zhen Tian, Xiaofeng Yang
Affiliation: Whinship Cancer Institute, Emory University, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Current cone-beam computed tomography (CBCT) typically requires no less than 200 degrees of angular projections, which prolongs scanning time and increases radiation exposure. To address thes...
Authors: Mostafa Cham, Matthias K Gobbert, Zhuoran Jiang, Sina Mossahebi, Ruth Obe, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma
Affiliation: University of Maryland School of Medicine, UMBC, University of Maryland Baltimore County, University of Maryland, Baltimore County, Stanford University, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc, Department of Infomation Systems, UMBC
Abstract Preview: Purpose: Compton camera (CC)-based prompt gamma imaging (PGI) offers real-time proton range verification. However, its limited-angle measurements cause severe distortions in PGI, affecting its clinica...
Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang
Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...
Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic
Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...
Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. Göksel, Görkem O. GĂŒngör, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan
Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman Sönmez Oncology Hospital
Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...
Authors: Peter Balter, Andres V Cibrian, Song Gao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The purpose of this study is to demonstrate a means of detecting misaligned jaw face angles on the Varian TrueBeam based on a beam symmetry metric for electron beam profiles.
Methods: Duri...
Authors: Ting Chen, Siming Lu, Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose: This study, the first in a two-part series, aims to determine the isocenter position and size for the MR Linac UNITY, focusing on the central axis (CAX) alignment of its Multi-Leaf Collimator...
Authors: Tanxia Qu, Hesheng Wang
Affiliation: NYU Langone Health
Abstract Preview: Purpose:
This study, the second in a two-part series, evaluates the isocenter position (the point in 3D space minimizing the sum of Euclidean distances to the MLC's central axis) and isocenter size...
Authors: Guang-Pei Chen, Nitish Chopra, Juan A. Garcia-Alvarez, Mi Huang, Slade J. Klawikowski, Haidy G. Nasief, George A. Noid, Abdul Parchur, Eric S. Paulson, Christina M. Sarosiek, Christopher Schultz
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: During routine delivery of mask-based Gamma Knife (GK) SRS, motion is tracked via the position of a reflective sticker placed on the patientâs nose relative to two stationary reflectors on th...
Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark
Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...
Authors: Morgan A. Daly, David J. Goodenough, Andrew M. Hernandez, John M. Hoffman, Joshua Levy, Michael F. McNitt-Gray, Ali Uneri, Bino Varghese
Affiliation: University of California, George Washington University, David Geffen School of Medicine at UCLA, Johns Hopkins Univ, University of Southern California, The Phantom Laboratory
Abstract Preview: Purpose: Quantitative imaging is affected by CT acquisition and reconstruction conditions, limiting robustness in multi-site or -scanner studies. This work aimed to develop a dataset that will enable ...
Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...
Authors: Julia Bauer, Tianxue Du, Katia Parodi, Marco Pinto, Thomas Tessonnier
Affiliation: Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Heidelberg Ion Beam Therapy Center (HIT), Department of Radiation Oncology, Heidelberg University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich)
Abstract Preview: Purpose:
Carbon ion therapy could benefit from range verification due to its sensitivity to range uncertainties. Positron emission tomography (PET) aids in this and comparing irradiation-induced PE...
Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...
Authors: Peter Balter, Elaine Eunnae Cha, Seungtaek Choi, Yao Ding, Eun Young Han, Yusung Kim, Rajat J. Kudchadker, Belinda Lee, Surendra Prajapati, Reza Reiazi, Ergys D. Subashi, Sarath Vijayan, Jinzhong Yang, Yao Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: This study evaluates the feasibility of an MR-only simulation, planning, and treatment (MROSPT) workflow for pelvic cancer patients using synthetic CT generated from MRI data. By validating s...
Authors: Abid Khan, Chad Klochko, Michael J Kovalchick, Hyeok Jun Lee, Hani Nasr, Krishnan Shyamkumar, Kundan S Thind
Affiliation: Henry Ford Radiology, Wayne State University, Henry Ford Health, HFHS
Abstract Preview: Purpose: Automated vascular segmentation in interventional angiography is challenged by contrast kinetics, vessel variations, and 2D projections, limiting the effectiveness of single-model approaches....
Authors: Md. Jobairul Islam
Affiliation: Department of Radiation Oncology, Labaid Cancer Hospital and Super Speciality Centre
Abstract Preview: Purpose: Electron radiotherapy is an effective treatment for superficial tumors but requires field-shaping devices like electron applicators, which are labor-intensive to produce. This study aimed to ...
Authors: Gregory T. Armstrong, James E. Bates, Kristy K. Brock, Laurence Edward Court, Matt Ehrhardt, Danielle Friedman, Aashish C. Gupta, Donald Hancock, Rebecca M. Howell, Cindy Im, Tera S Jones, Choonsik Lee, Wendy Leisenring, Taylor Meyers, Lindsay Morton, Chaya Moskowitz, Joe Neglia, Vikki Nolan, Caleb O'Connor, Kevin C. Oeffinger, Constance A. Owens, Arnold C. Paulino, Chelsea C. Pinnix, Sander Roberti, Cecile Ronckers, Susan A. Smith, Kumar Srivastava, Lucie Turcotte
Affiliation: Department of Medicine, Duke University School of Medicine, Department of Epidemiology and Cancer Control, St. Jude Childrenâs Research Hospital, The University of Texas MD Anderson Cancer Center, Department of Oncology, St. Jude Childrenâs Research Hospital, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, Division of Pediatric Epidemiology and Clinical Research, University of Minnesota, Division of Childhood Cancer Epidemiology, University Medicine at Johannes Gutenberg University Mainz, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Pediatrics, University of Minnesota, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Biostatistics, St. Jude Childrenâs Research Hospital, Clinical Research Division, Fred Hutchinson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences
Abstract Preview: Purpose: To (1) develop and validate a novel anatomically realistic pediatric/adolescent population-based breast model, (2) incorporate model into an age-scalable female reference phantom, and (3) dem...
Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...
Authors: Yona Choi, Kyo-tai Kim, Seungwoo Park, Dung Thi Tran
Affiliation: Gemss Health Care Inc,, Korea Institute of Radiological & Medical Sciences
Abstract Preview: Purpose: We developed shielding materials and a hybrid concept collimator for fluoroscopy to reduce the dose to normal tissues outside the treatment field, which are capable of quantifying dose rate a...
Authors: Kaile Li
Affiliation: Alexander T. Augusta Miliary Medical Center
Abstract Preview: Purpose: To develop a experimental method in observation of beam profile transfer model in intensity modulated radiotherapy (IMRT).
Methods: A picket fence plan was generated in Eclipse treatment p...
Authors: Henry Szu-Meng Chen, Mu-Lan Jen, Vinodh A. Kumar, Ho-Ling Anthony Liu, Jian Ming Teo
Affiliation: School of Medicine, University of Colorado Denver, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Resting-state (rs-) fMRI detects functional networks by measuring synchronization of low-frequency oscillations in blood-oxygenation-level-dependent (BOLD) signals between brain regions. Stan...
Authors: Soo Hyun Byun, Troy Farncombe, Edcer Jerecho DC Laguda
Affiliation: McMaster University
Abstract Preview: Purpose: We present the adaptation of a Cadmium Zinc Telluride (CdZnTe) detector, initially designed for SPECT-MR applications, to neutron imaging. This study explores a novel technique that utilizes ...
Authors: Wenchao Cao, Yingxuan Chen, Haisong Liu, Wenyin Shi, Wentao Wang, Lydia J. Wilson, Zhenghao Xiao
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Multi-target stereotactic radiosurgery (SRS) planning poses challenges due to complex geometries, small target volumes, and steep dose gradients. Achieving a balance between target coverage a...
Authors: Yaowen Cao, Haonian Gong, Yue Gu, Meiqi Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Xiaogang Yuan
Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China
Abstract Preview: Purpose: Magnetic resonance imaging (MRI)-guided proton therapy is an innovative technology that combines superior soft tissue imaging capabilities of MRI with the high dose conformity of proton thera...
Authors: John M. Boone, Andrew M. Hernandez, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: Johns Hopkins University, University of California, UT MD Anderson Cancer Center, University of New Mexico Albuquerque, UC Davis Health
Abstract Preview: Purpose: To significantly improve image quality relative to clinically deployed digital breast tomosynthesis (DBT) systems, which use a 1D acquisition geometry (an arc), with a 2D image acquisition ge...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Diandra Ayala-Peacock, Lindsey Hendricks Bloom, Oana I. Craciunescu, Julie A. Raffi, Megan K. Russ, Ryan Sanford, Rajesh Venkarataman
Affiliation: Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, Duke University Medical Center, Duke University, Eigen Health, Duke Univesity
Abstract Preview: Purpose: To establish a robust QA framework to characterize and ensure accuracy, reliability, and reusability of a transrectal ultrasound (TRUS)-based needle tracking system (NTS) for clinical HDR GYN...
Authors: Yaowen Cao, Yunwen Huang, Yidong Yang, Xiaogang Yuan, Ning Zhao, Cheng Zheng
Affiliation: Department of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China
Abstract Preview: Purpose: MRI has better soft tissue contrast than cone beam CT which is commonly used in image guided radiotherapy. This study aims to develop a low-field MRI system for precision small animal radiati...
Authors: Penghao Gao, Zejun Jiang, Huazhong Shu, Linlin Wang, Gongsen Zhang, Jian Zhu
Affiliation: Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration, Southeast University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: We propose a cascading framework for time-varying anatomical volumetric reconstruction and tumor-tracking, guided by onboard orthogonal-view X-ray projections.
Methods: We employe multiple...
Authors: Pierre Gardair, Johnathan E Leeman, Claire Keun Sun Park, Atchar Sudhyadhom
Affiliation: Brigham and Womenâs Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School, Harvard Medical School
Abstract Preview: Purpose: Dose is a poor surrogate for radiobiological damage but no in vivo technology exists to directly measure damage such as DNA strand breaks and free radical generation (FRG). Recent advances in...
Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma
Affiliation: University of Pennsylvania, Mayo Clinic
Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...
Authors: Theresa Busch, Robert H Hadfield, Madelyn Johnson, Baozhu Lu, Hongjing Sun, Brian C. Wilson, Weibing Yang, Timothy C. Zhu
Affiliation: University of Glasgow, University of Toronto, University of Pennsylvania
Abstract Preview: Purpose: Direct detection of singlet-state oxygen (ÂčOâ) is crucial for advancing type II photodynamic therapy (PDT), but its short lifetime makes in vivo measurement highly challenging. Although Photo...
Authors: Thomas R. Bortfeld, Prof. Elisabetta De Bernardi, Tianxue Du, Beatrice Foglia, Chiara Gianoli, Takamitsu Masuda, Katia Parodi, Marco Pinto, Boon-Keng Kevin Teo, Yunhe Xie
Affiliation: Department Of Radiation Oncology, Massachusetts General Hospital (MGH), School of Medicine and Surgery, University of Milano-Bicocca, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, National Institutes for Quantum Science and Technology (QST), University of Pennsylvania, Department of Experimental Physics - Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen
Abstract Preview: Purpose: The full potential offered by protons in clinical practice is limited by range uncertainties. One possibility for monitoring is through secondary prompt gammas (PG). PG emission along the pen...
Authors: Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz
Affiliation: UT Health San Antonio, University of Texas HSC San Antonio
Abstract Preview: Purpose: To evaluate dosimetric accuracy of Brainlab Elements (BLE) 4.0 treatment planning system (TPS) for linac based SRS and Spine SBRT treatment.
Methods: RT Safe cranial and thorax phantoms wi...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Aliasghar Rohani, Rui Zhang
Affiliation: Louisiana State University, Baton Rouge, Louisiana, Department of Radiation Oncology, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the impact of simultaneous optimization of multi-photon beam energy and fluence on IMRT and VMAT treatment planning.
Methods: An Elekta linear accelerator (lin...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Arnab Chakravarti, Nilendu Gupta, Sagarika Jain, Maximilian Stephen Meineke, Allison N. Palmiero, Runhe Tan
Affiliation: The Ohio State University - James Cancer Hospital, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, The James Cancer Center
Abstract Preview: Purpose: Ultra-High Dose Rate Radiation Therapy (UHDR-RT) induces normal tissue sparing while maintaining iso-effective tumor control compared to conventional methods, known as the âFLASH effectâ. How...
Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center
Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectorsâą for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...
Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the dosimetric effects of patient positioning errors, including setup inaccuracies and yaw deviations, on dual-isocenter volumetric modulated arc therapy (VMAT) plans for...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZAP-X is the newest cranial stereotactic radiosurgery (SRS) platform. Small-volume structures usually found in the head and neck may be susceptible to dose-volume averaging, which has not bee...
Authors: Nguyen Phuong Dang, Mason Hazlett, Lijun Ma, Yutaka Natsuaki, William T. Watkins, Zhengzheng Xu, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, Radiation Oncology, Keck School of Medicine of USC, RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center
Abstract Preview: Purpose: This is the first study reporting the beam dosimetric parameter cross-checks of Reflexion linac using different water phantom systems and detectors. The difference in measurements using diffe...
Authors: J Isabelle Choi, Meng Wei Ho, Isabel Lin, Hang Qi, Qi Zeng, Ajay Zheng
Affiliation: New York Proton Center, Scarsdale High School
Abstract Preview: Purpose: Proton therapy is a promising treatment modality for breast cancer due to its unique dosimetric advantage. Accurate dose calculation is critical to ensure effective treatment outcomes. The fo...
Authors: Darren Kaplan, Chenguang Liu, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center
Abstract Preview: Purpose: This study evaluates the hypothesis that surface-guided radiation therapy for the breast or chest wall using proton PBS provides comparable target coverage and OARs sparing to x-ray-based IGR...
Authors: Daniel H. Bushe, Arthur Lalonde, Hoyeon Lee, Harald Paganetti, Brian Winey
Affiliation: Universite de Montreal, Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School, University of Hong Kong
Abstract Preview: Purpose: Improving the precision and fidelity of daily volumetric imaging is essential for enabling adaptive proton therapy (APT). While cone-beam CT (CBCT) provides daily volumetric imaging, their ut...
Authors: Daniel A. Alexander, Jeffrey D. Bradley, Steven J. Feigenberg, Cole Friedes, Casey Hollawell, William Levin, Maksym Sharma, Boon-Keng Kevin Teo, Ying Xiao, Nikhil Yegya-Raman, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology and Applied Sciences, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: To investigate lung function changes following definitive chemoradiation dose using CT-derived measurements in patients with locally advanced NSCLC at 6-months post-treatment compared to pre-...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: Dynamic Winston-Lutz (WL) testing provides a comprehensive framework for evaluating the accuracy of isocenter alignment. This study investigates the impact of dynamic beam modulation, such as...
Authors: Jingying Lin, Stevan Pecic, Strahinja Stojadinovic
Affiliation: University of Belgrade, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: This study aims to determine the magnitude of polarization-induced dosimetric error for EBT4 films at different scanning orientations, and to provide guidance on selecting appropriate regions...
Authors: Amar Kishan, Jun Lian, Yunkui Pang, Jonathan Pham, X. Sharon Qi, Michael Steinberg, Luca F Valle, Pew-Thian Yap
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of North Carolina at Chapel Hill
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) is a highly effective treatment for prostate cancer, yet predicting genitourinary (GU) toxicity has primarily relied on planned dosimetry. This study inv...
Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center
Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Nishan Shrestha
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study aims to quantify the dose discrepancy associated with improper placement of the Leipzig applicator on the patient's skin.
Methods: Monte Carlo simulations were performed using t...
Authors: Prasanna Alluri, Mona Arbab, Xingzhe Li, Chang-Shiun Lin, Mu-han Lin, David D.M. Parsons, Asal Rahimi, Justin D. Visak, Narine Wandrey
Affiliation: UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Intelligence-Optimization-Engine (IOE) v1.0 relied heavily on planner expertise and patient-specific IMRT beam arrangements, requiring frequent revisions. While VMAT workflows offered potenti...
Authors: Chieh-Ya Chiu, Shen-Hao Li, Hsin-Hon Lin, Shu-Wei Wu
Affiliation: Department of Medical Imaging and Radiological Sciences, Chang Gung University, Proton and Radiation Therapy Center, Chang Gung Memorial Hospital Linkou
Abstract Preview: Purpose: Monte Carlo simulation enables precise calculation of dose distribution in proton therapy through tracing the radiation particles with patient tissues. However, achieving clinical-level preci...
Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaël Ndoutoume-Paquet, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, Laval University, Princess Margaret Cancer Centre, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Nuclear Medicine Department, Hospital Regional de Antofagasta
Abstract Preview: Purpose: Modelling electronic brachytherapy (eBT) sources is difficult because of the high-dose gradients and challenges associated with low-energy modelling. This study examines the accuracy of avail...
Authors: Lian Duan, Stephen F. Kry, Hunter S. Mehrens, Christine Peterson, Paige A. Taylor
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: To develop predictive models for IROC SRS head phantom audits and to identify important factors influencing institutional performance.
Methods: The IROC SRS head phantom includes two TLDs ...
Authors: Michael Butkus, Camilo M. Correa Alfonso, Olga M. Dona Lemus, James Arthur Perez-Sanchez
Affiliation: University of Miami
Abstract Preview: Purpose: Accurate skin dose calculation is essential for treating superficial lesions such as those of the breast, chest wall, and scalp. Clinical treatment planning systems often rely on approximatio...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Accurate delineation of the urethra is critical for optimizing tumor control and minimizing urethral toxicity in prostate stereotactic body radiation therapy (SBRT). The purpose of this study...
Authors: Samira Dabaghmanesh, Beth A. Erickson, William Hall, Jason Hirshberg, An Tai
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Treatment plan evaluation for minimizing duodenal toxicity often involves multiple dose-volume constraints that vary based on fractionation. The Equivalent Uniform Dose (EUD) has emerged as a...
Authors: Ruth Afanador, Daniela Branco, John M Bryant, John Campbell, Clement Chaphuka, Samuel A. Einstein, David B. Flint, Jeffrey R. Kemp, Mussa Kumwembe, Daniel J Mollura, Joseph Weygand
Affiliation: RAD-AID International, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, UNC Health, Malawi National Cancer Center, Kamuzu Central Hospital, Penn State College of Medicine, Sutter Health, New York University, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose: Malawi, a landlocked country in southeastern Africa with a population of over 20 million, ranks among the worldâs least-developed nations and has the fourth-lowest gross domestic product per ...
Authors: Rajeev Gupta, Shriram Ashok Rajurkar, Teerthraj Verma
Affiliation: King George's Medical University, King George's Medical University, UP
Abstract Preview: Purpose:
The volunteer deep inspiration breath hold (vDIBH) technique is used to reduce the heart dose in left breast cancer radiotherapy. Many times, it is faced that despite rigorous exercise and...
Authors: Ramin Abolfath, Alejandro Bertolet, Kofi M. Deh, Rao Khan, Vanessa Sanders, Daniel Suarez-Garcia
Affiliation: Massachusetts General Hospital and Harvard Medical School, University of Sevilla, Brookhaven National Laboratory, Howard University
Abstract Preview: Purpose: To compare the efficacy of 225Ac to 90Y for local cancer therapy by quantifying DNA damage using Monte Carlo simulations.
Methods: The TOPAS n-Bio toolkit was used to simulate the irradiat...
Authors: Brecca Bettcher, Tobey J Betthauser, Bradley T Christian, Sterling Johnson, Lisette LeMerise, Max McLachlan, Andrew McVea, Dhanabalan Murali, Ali Pirasteh, Matthew Zammit
Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center
Abstract Preview: Purpose: The radiotracer [18F]NAV4694 is a desirable alternative to [11C]PiB for measuring amyloid neuropathology related to Alzheimerâs disease (AD), possessing similar imaging characteristics and fa...
Authors: Girish Bal, Ke Colin Huang, Christopher F. Njeh, Oluwaseyi Oderinde, Yong Yue
Affiliation: Purdue University, RefleXion Medical, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Biology-guided radiotherapy (BgRT) uses real-time positron emission tomography (PET) signals to precisely direct radiotherapy beamlets. The success of BgRT planning and delivery relies on PET...
Authors: Emily Hansen, Jay Mistry, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: SCINTIX Biology-guided radiotherapy (BgRT) on the RefleXion X1 relies on a new planning system and advanced planning techniques. The first patient SCINTIX BgRT plans are compared to similar c...
Authors: Yijian Cao, Jenghwa Chang, Nicholas Coupey, Lyu Huang, Jessica Jung
Affiliation: Northwell, Hofstra University Medical Physics Program
Abstract Preview: Purpose:
The Synergy bioabsorbable polymer (BP) stent, made of Platinum Chromium Alloy, is widely utilized in treating coronary artery disease. This study investigates dose perturbations caused by ...
Authors: Ben Archibald-Heeren, Grace Gwe-Ya Kim, Kelly Kisling, Xenia Ray
Affiliation: UC San Diego, Icon Cancer Centres, University of California, San Diego, University of California San Diego
Abstract Preview: Purpose: To evaluate improvements in external beam plans for gynecological cancers from a novel planning solution: RapidArc Dynamic (RAD) (Varian Medical Systems, Palo Alto, CA) which optimizes VMAT w...
Authors: Blessing Chinelo Akah, Daniel W. Neck, David J. Perrin, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: To assess the reliability of the Aktina Isopoint software in evaluating different components of the linear accelerator for optimized quality assurance and linac performance
Methods: The Ak...
Authors: Sunil Mani, Ilakiya Raghavendiran, Vasanthan Sakthivel, Skanda Kabilan Swamy
Affiliation: Edmond Santa Fe High School, Edmnd Deer Creek High, Cancer Specialists of North Florida, Advanced Medical Physics
Abstract Preview: Purpose: Purpose/Objective(s): To evaluate and validate the dose calculation and delivery accuracy for patients planned using diagnostic CT
Methods: A total of forty-two patients with palliative sp...
Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang
Affiliation: Cincinnati Children's Proton Therapy Center
Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...
Authors: Ali Ammar, Quan Chen, Yi Rong, Libing Zhu
Affiliation: Mayo Clinic Arizona
Abstract Preview: Purpose: To investigate how defacing algorithms, essential for patient privacy in data sharing, impact AI-based segmentation performance in CT imaging for radiation therapy. This study evaluates wheth...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: DynamicARC is a novel pencil beam scanning (PBS) proton therapy technique with the potential to provide more conformal dose distributions and reduce treatment time. This study investigates th...
Authors: Elizabeth M. Alves, Alistair K. Templeton, Julius V. Turian
Affiliation: Rush University Medical Center
Abstract Preview: Purpose: To test the performance of two similar, but not beam-matched, linacs in interchangeably delivering IMRT and VMAT patient-specific quality assurance (PSQA) tests.
Methods: Two TrueBeam lina...
Authors: Shatha Al Afifi, Hana Baroudi, Leonard Che Fru, Laurence Edward Court, Suzanne B. Evans, Kent A. Gifford, Adam D. Melancon, Melissa P. Mitchell, Issa Mohamad, Patricia Murina, Manickam Muruganandham, Tucker J. Netherton, Callistus M. Nguyen, Joshua S. Niedzielski, Deborah L. Schofield, Simona Shaitelman, Willie Shaw, Sanjay S. Shete, Adam Shulman, Brendon Smith, Sheeba Thengumpallil, Carlos Daniel Venencia, Conny Vrieling
Affiliation: University of Cape Town, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, University of the Free State, UT MD Anderson Cancer Center, King Hussein Cancer Center, Instituto Zunino - Fundacion Marie Curie, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Dra., Hirslanden Clinique des Grangettes, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Therapeutic Radiology, Yale University School of Medicine, Yale University, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose:
Automated contouring and planning tools are usually trained on single-institution datasets, seldom tested across diverse patient populations. This introduces a risk of population bias, res...
Authors: Yongha Gi, Jinju Heo, Jinyoung Hong, Yunhui Jo, Yousun KO, HyeongJin Lim, Sang Yoon PARK, Myonggeun Yoon
Affiliation: Korea University, Institute of Global Health Technology (IGHT), Korea University, Republic of Korea
Abstract Preview: Purpose: To evaluate the effectiveness of the gradient magnitude (GM) feature of the entorhinal cortex, observed in T1 MR images, in dementia classification.
Methods: A total of 1,422 ADNI T1 MR da...
Authors: Shifeng Chen, Mariana Guerrero, Michael J. MacFarlane, Huijun Xu, Baoshe Zhang, Jinghao Zhou
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Capital Region Medical Center, University of Maryland Shore Regional Cancer Center
Abstract Preview: Purpose: The clinical value of surface-guided radiotherapy (SGRT) in prone breast cancer setups is much less established than in supine setups. This study explores SGRT's potential for prone breast pa...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Xiuxiu He, Tianfang Li, Xiang Li, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
This work aims to develop an innovative technique to evaluate patientsâ daily respiratory pattern using three-dimensional (3D) deformation vector fields (DVF) derived from a free-breathing...
Authors: Yu-Ying Lin, Yu Chen Shen
Affiliation: Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou
Abstract Preview: Purpose: This study evaluates the protective efficiency of lead glasses against radiation exposure to the eyes during angiography using optically stimulated luminescence dosimeters (OSLDs).
Methods...
Authors: Li Tong, Chuyan Wang, Zhengkui Wang, Yingli Yang, Jie Zhang
Affiliation: Shanghai United imaging Healthcare Advanced Technology Research Institute, Shanghai United Imaging Healthcare Co., LTD, Department of Radiology, Ruijin Hospital, Institute for Medical Imaging Technology, Ruijin Hospital
Abstract Preview: Purpose:
Pelvic radiotherapy (RT)-induced bone marrow (BM) damage affects patient prognosis by causing hematologic toxicity. However, consensus on BM-sparing (BMS) RT is still lacking, owing to the...
Authors: Xinhui Duan, Vivek Nair, Liqiang Ren, KyuHo Song, Vasantha Vasan, Kuan Zhang, Yue Zhang
Affiliation: Department of Radiology, UT Southwestern Medical Center
Abstract Preview: Purpose: Minimizing radiation dose is crucial in CT colonography (CTC) screening and diagnosis. Tin (Sn) prefiltration is readily incorporated into clinical photon-counting CT (PCCT) scanners, yet its...
Authors: Brian D. Casto, Mathew Y Kang, Lichung Ku, Samuel J Wang, Joseph B. Ying, Walker Ray Zimmerman
Affiliation: Salem Health Cancer Center, Salem Health
Abstract Preview: Purpose: Varian HyperArc is an advanced radiotherapy module designed to efficiently deliver high-quality multi-target stereotactic radiosurgery (SRS) treatment plans on Varian linacs. However, the int...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXionÂź X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson
Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...
Authors: Christian Fiandra, Marco Fusella, Gianfranco Loi, Silvia Pesente, Lorenzo Placidi, Claudio Vecchi, Orlando Zaccaria, Stefania Zara
Affiliation: Abano Terme Hospital, University of Turin, Maggiore della CaritĂ , Tecnologie Avanzate Srl, Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abstract Preview: Purpose: Deformable-image-registration (DIR) is essential in modern radiotherapy for adaptive RT, re-irradiation, and other clinical applications. Multimodal DIR is especially important in MRI-only wo...
Authors: Sabrina Campelo, Sandun Y. Jayarathna, Adam D. Melancon, Paige L. Nitsch, Christopher Ryan Peeler, Julianne M. Pollard-Larkin, Ramaswamy Sadagopan, Xiaochun Wang, George Zhao
Affiliation: The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Development of an in-house analytical simulation for streamlining photon counting detector (PCD) system protocols through measuring transmitted photon energy spectra through a Hafnium (Hf)-lo...
Authors: Qiu Tang, Yeqiang Tu, Jiahao Wang, Lu Wang
Affiliation: Women's Hospital School of Medicine Zhejiang University, Hangzhou Women's Hospital
Abstract Preview: Purpose: The BT boost regions were previously delineated and optimized during EBRT planning process. The differences of DVH parameters addition (PA), deformable dose summation (DS) with BT boost regio...
Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu
Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University
Abstract Preview: Purpose: To systematically evaluate the relationship between Activity Concentration (AC) obtained from the RefleXion PET-Linac with the maximum standardized uptake value (SUVmax) derived from a diagno...
Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC
Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyonâs doub...
Authors: Peter Balter, Thomas Alexander Cuthbert, Weiliang Du, Song Gao, Nicholas Zacharopoulos
Affiliation: Aktina Medical Corp, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The purpose of this study is to evaluate the accuracy and reproducibility of a commercial product for verifying the size, location, and coincidence of physical isocenter (P_iso) and radiation...
Authors: Edwin Quashie, Yun Wang
Affiliation: Indiana University Medical School, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: To provide a formal evaluation for the TrueBeam linac matching process before, during and after the commission of the newly installed TrueBeam linac which we want to match to an existing True...
Authors: Emily Y. Hirata, Xiaoyu Sherry Liu, Evan Porter, Manju Sharma
Affiliation: University of California San Francisco, University of California, San Francisco, University of California
Abstract Preview: Purpose:
The Varian Halcyon Linear Accelerator has become increasingly popular in both community hospitals and academic institutions due to its user-friendly design and operational efficiency. This...
Authors: Oi-Wai Chau, Beata Gontova Bernat, Mary Gronberg, Yao Hao, Amanda M. Jackson, Nupur Karmaker, Dishane Chand Luximon, Osama R. Mawlawi, Ikechi Samuel Ozoemelam, Deepak Shrestha, William Swanson, Md Tofiz Uddin, Joseph Weygand, Afua A. Yorke
Affiliation: University of Michigan, Mayo Clinic, Champion Cancer Center, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, Washington University in St Louis, Washington University School of Medicine, Department of Radiation Oncology, University of California, Los Angeles, National Institute of Cancer Research and Hospital, Emory University, Dept. of Medical Physics and Biomedical Engineering, Gono Bishwabidyalay, The University of Texas Southwestern Medical Center
Abstract Preview: Purpose: To evaluate perception and awareness of global medical physics (GMP) as a career path among medical physics professionals and trainees, identify opportunities to enhance professional developm...
Authors: Jeff Boob, Jaydev K. Dave, Tim Minch, Bhavyata Tanna
Affiliation: Dr. Ronald E. McNair Academic High School, Mayo Clinic, CurveBeam AI
Abstract Preview: Purpose: To compute effective doses associated with imaging of the extremities with a HiRise (CurveBeam AI, Hatfield, PA) cone-beam CBCT scanner specifically designed for weight-bearing imaging of the...
Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis
Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...
Authors: Bing-Hao Chiang, Eric C. Ford, Juergen Meyer, Timothy D. Solberg
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington
Abstract Preview: Purpose: This study evaluated the potential risk reduction of various pretreatment patient-specific quality assurance (PSQA) programs for Intensity Modulated Radiation Therapy (IMRT) in mitigating fai...
Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer
Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...
Authors: Louis Archambault, Nicolas Drouin, Alexis Horik, Simon Thibault
Affiliation: Département de Physique, de Génie Physique et D'optique, et Centre de Recherche sur le Cancer, Université Laval, Département de Physique, de Génie Physique et D'optique, et Centre d'optique, photonique et laser, Université Laval
Abstract Preview: Purpose: To develop a novel type of real-time 3D dosimeter for the quality assurance of linear accelerators used in external beam radiotherapy.
Methods: An experimental setup was constructed using ...
Authors: Weigang Hu, Zhenhao Li, Jiazhou Wang, Xiaojie Yin, Zhen Zhang
Affiliation: Fudan University Shanghai Cancer Center
Abstract Preview: Purpose:
This study aims to develop and validate a novel deep learning method to generate synthetic PET images for rectal cancer from MRI data. By incorporating metabolic information from the synth...
Authors: Lindsay Hammons, Lisa Baumann Kreuziger, Haidy G. Nasief, Matthew Scheidt, Farrell Sean, Antonio Sosa Lozano
Affiliation: Division of Hematology and Oncology, University of Washington, Vascular and Interventional Radiology, Medical college of wisconsin, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Venous thromboembolism, which includes pulmonary embolism (PE), is the third leading cause of acute cardiovascular syndrome behind myocardial infarction and stroke. Current research categoriz...
Authors: Noriko Kishi, Takashi Mizowaki, Mitsuhiro Nakamura, Yukine Shimizu
Affiliation: Kyoto University, Kyoto Univercity, Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University
Abstract Preview: Purpose: To predict tumor positions in markerless dynamic tumor tracking (ML-DTT)-VMAT by compensating for the asynchrony between the tumor and the diaphragm.
Methods: Rotational fluoroscopic X-ray...
Authors: Yiran Liu, Zhengzheng Liu, Fang-Fang Yin
Affiliation: Duke Kunshan Univeristy, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: To investigate the feasibility of producing high dose rate GRID therapy using a compact linear accelerator (LINAC) treatment head with scanning beam and stationary grid collimator.
Methods...
Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker
Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago
Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...
Authors: Tae Kyu Lee
Affiliation: Allina Health
Abstract Preview: Purpose: To assess the feasibility of a dynamic-platform integrated with high-resolution patient-specific-quality-assurance (PSQ device for periodic quality assurance (PQA) and PSQA in respiratory-gat...
Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Renan Felix dos Santos, Gustavo Freire Pereira da Silva, Alessandra Tomal
Affiliation: University of SĂŁo Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de FĂsica Gleb Wataghin
Abstract Preview: Purpose: Evaluate the feasibility of a bench-top PCCT using Geant4 Monte Carlo simulations. The study applied the Geant4 framework on determining the electronic density of materials as a function of C...
Authors: Robert A. Corns, Mohammad Kanber
Affiliation: East Carolina University, East Carolina University Brody School of Medicine
Abstract Preview: Purpose:
Accurate determination of the radiation isocenter is crucial for precise radiotherapy treatments, directly impacting patient safety and treatment quality. This study presents a computation...
Authors: Xiangli Cui, Chunyan Fu, Man Hu, Wanli Huo, Jingyu Liu, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, Department of Oncology, Xiangya Hospital, Central South University, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose: To quantify the impact of fine-tuning strategies for pre-trained AI image generation models on glioma MRI image quality and observer performance, and to determine the optimal fine-tuning conf...
Authors: Niels Bassler, Jonathan Bortfeldt, Davide Boscaini, Francesco Evangelista, Guyue Hu, Ze Huang, Margarita Kozak, Julie Lascaud, Giulio Lovatti, Eero Lönnqvist, Jasper Nijkamp, Munetaka Nitta, Prasannakumar Palaniappan, Katia Parodi, Marco Pinto, Per R. Poulsen, Marco Riboldi, Babak Sharifi, Brita Singers SÞrensen, Peter Thirolf
Affiliation: Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t MĂŒnchen (LMU Munich), Ludwig-Maximilians UniversitĂ€t, Danish Centre for Particle Therapy, Aarhus University Hospital, Department of Medical Physics, Ludwig-Maximilians-UniversitĂ€t (LMU) MĂŒnchen, Department of Experimental Clinical Oncology, Aarhus University, Department of Oncology, Aarhus University Hospital
Abstract Preview: Purpose: To perform the first in vivo application of a novel small animal radiation research platform combining on-board image-guidance with multi-field intensity modulated spot scanning delivery [1] ...
Authors: Ben Durkee, Renata Farrell, Carri K. Glide-Hurst, Colin Harari, Alex Singleton Kuo, Chase Ruff, Jordan M. Slagowski, Yuhao Yan
Affiliation: University of Wisconsin, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Advances in upright CT and patient positioning system now enables high quality daily CT imaging and treatment delivery in the upright position, providing benefits including reduced internal m...
Authors: Jihun Kim, Jin Sung Kim, Jun Won Kim, Yong Tae Kim, Chanwoong Lee, Jihyn Pyo, Young Hun Yoon
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine
Abstract Preview: Purpose: Although segmentation foundation models have recently demonstrated promising zero-shot performance on natural images, its clinical application to magnetic resonance (MR) images still requires...
Authors: Zachary Buchwald, Chih-Wei Chang, Zach Eidex, Hui Mao, Richard L.J. Qiu, Justin R. Roper, Mojtaba Safari, Hui-Kuo Shu, Xiaofeng Yang, David Yu
Affiliation: Emory University and Winship Cancer Institute, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Emory University School of Medicine
Abstract Preview: Purpose: MRI-guided radiation therapy (MRgRT) benefits significantly from enhanced soft-tissue contrast and spatial resolution, which aid in accurately delineating tumors and organs at risk. Although ...
Authors: Ming Chao, Karyn A Goodman, Yang Lei, Tian Liu, Jing Wang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Real-time volumetric MRI is essential for motion management in MRI-guided radiotherapy (MRIgRT), yet acquiring high-quality 3D images remains challenging due to time constraints and motion ar...
Authors: Ross I. Berbeco, Vera Birrer, Raphael Bruegger, Pablo Corral Arroyo, Roshanak Etemadpour, Dianne M. Ferguson, Rony Fueglistaller, Thomas C. Harris, Yue-Houng Hu, Matthew W. Jacobson, Mathias Lehmann, Nicholas Lowther, Daniel Morf, Marios Myronakis
Affiliation: Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, Dana Farber/Brigham and Women's Cancer Center, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Womens Hospital, Dana Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Varian Imaging Laboratory, Dana-Farber Cancer Institute
Abstract Preview: Purpose: Applications of combined kV-MV CBCT include metal artifact correction and material identification. Difficulties arise, however, when the imagers have misaligned geometric perspectives of the ...
Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...
Authors: Stephen M. Avery, Izabella L. Barreto, Oi-Wai Chau, Cesar Della Biancia, Beata Gontova Bernat, Amanda M. Jackson, Rao Khan, Eugene P. Lief, Osama R. Mawlawi, Wilfred F. Ngwa, Christopher F. Njeh, Peter Allan Sandwall, William Swanson, Joseph Weygand, Afua A. Yorke
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, VA Medical Center, Johns Hopkins University, Mayo Clinic, Champion Cancer Center, Howard University, UT MD Anderson Cancer Center, Department of Radiation Oncology and Applied Science, Dartmouth Health, University of Washington, University of Florida College of Medicine, Washington University in St Louis, Emory University, University of Pennsylvania, OhioHealth, Indiana University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: To assess needs of medical physicists working in low-and-middle-income countries (LMICs)
Methods: A survey was developed by AAPMâs Global Needs Assessment Committee (GNAC) in partnership w...
Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: Davide Brivio, Lia Carroll, Juliane Daartz, Jan PO Schuemann, Piotr Zygmanski
Affiliation: Massachusetts General Hospital, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: We employ High-Energy Current (HEC) detectors for real-time monitoring of proton beams at conventional to FLASH dose rates. This would help overcome the need for fast and accurate dosimeters ...
Authors: So Hyun Ahn, Chris Beltran, Byongsu Choi, Jeong Heon Kim, Jin Sung Kim, Bo Lu, Justin Chunjoo Park, Bongyong Song, Jun Tan
Affiliation: Mayo Clinic, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Ewha Medical Research Institute, Ewha Womans University College of Medicine, UC San Diego, Yonsei University College of Medicine
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) is widely used in IGRT for patient positioning but suffers from low resolution and poor soft tissue contrast. Synthetic CT (sCT) generated from CBCT ad...
Authors: Yu Gao, Lei Xing, Siqi Ye
Affiliation: Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) scans are often the only option for non-coplanar radiation therapy to prevent potential mechanical collisions. However, the consecutive angular occlusion of pr...
Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: This study introduces a novel spatiotemporal Gaussian neural representation framework to reconstruct high-temporal dynamic CBCT images from 1-minute acquisition, preserving motion dynamics an...
Authors: John Ginn, Chenlu Qin, Deshan Yang
Affiliation: Duke University, Department of Radiation Oncology, Duke University
Abstract Preview: Purpose: Clinical implementation of auto-segmentation tools has been hindered by poor interpretability and generalizability of AI models, necessitating the development of automated contour quality ass...
Authors: Salman M. Arnab, Yves Chevalier, Samuel Gagné, Adrian F. Howansky, Luc LaperriÚre, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Analogic Canada
Abstract Preview: Purpose: A direct-indirect dual-layer flat-panel-detector (DI-DLFPD) is under development for patient motion artifact-free contrast-enhanced digital mammography (CEDM). DI-DLFPD comprises a direct fro...
Authors: Ulrike Dydak, Chia-Tien Hsu, Chang Geun Lee, Cora Mizimakoski, Humberto Monsivais, Jae Hong Park
Affiliation: Purdue University
Abstract Preview: Purpose: Overexposure to manganese (Mn) from inhaling welding fumes can lead to cognitive and motor deficits. We developed a whole-brain Mn-mapping approach to detect subtle but significant increases ...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
It has been challenging to acquire clinically useful MR images of pediatric cancer patients without anesthesia, and MR contrast agents. Custom-made immobilization devices and optimization ...
Authors: Jaydev K. Dave, Krzysztof R Gorny, Chunming Gu, Nicholas J. Hangiandreou, Gina K. Hesley, Myung-Ho In, Zaiyang Long, Aiming Lu, Christin A. TiegsHeiden
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
MR-guided focused ultrasound (MRgFUS) enables precise tumor ablation with real-time MR-thermometry guidance. Our practice is exploring the potential use of Feraheme (Ferumoxytol), a superp...
Authors: Maria Jose Almada, Oscar Apaza, Carlos Bohorquez, Ezequiel Cabrera, Rogelio Diaz Moreno, Maximiliano Musso, Rosa Petit, Carlos Daniel Venencia, Lucy D. Wolfsberger
Affiliation: LAP, FaMAF, UNC, Instituto Zunino - Fundacion Marie Curie
Abstract Preview: Purpose:
PSQA employs gamma analysis to verify the planned versus delivered dose. Evaluating the effectiveness of PSQA techniques in identifying errors is crucial. This study aims to incorporate ML...
Authors: Xinhua Li, Jie Zhang, Yifang (Jimmy) Zhou
Affiliation: University of Kentucky, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Fat volume fraction (FVF) is an important biomarker for non-alcoholic fatty liver disease. CT can be a good modality for FVF assessment if the accuracy is adequate. We aimed to study the impa...
Authors: Angela J Da Silva, Andrew Groll, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: PET-based biology-guided radiotherapy (BgRT) is a radiation therapy technique that uses PET imaging to deliver tracked dose to the tumor in real-time. We characterized the delivery accuracy o...
Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Anthony Nagy, Stéphane Nevesny, Nicolas Joel Lionel Perichon
Affiliation: Clinique De Genolier
Abstract Preview: Purpose: Real-time tracking is implemented on Radixact by detecting the target position with 2D-kV image either directly (for lung tumors), or indirectly (using fiducials as surrogates), and by adapti...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Richard Dortch, Thammathida Ketsiri, Zhiqiang Li, Shiv P. Srivastava
Affiliation: Barrow Neurological Institute, Dignity Health Cancer Institute, St. Joseph's Hospital & Medical Center
Abstract Preview: Purpose: Imaging the spinal cord post-surgery is challenging due to metal surgical implants, which induce signal loss and geometric distortions. Together, this hinders the visualization of the spinal ...
Authors: Morgan Aire, Krystal M. Kirby, Olivia Magneson, David E. Solis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: For soft-tissue abdominal tumors, a 4D-MR may provide improved tumor tracking over the clinical standard 4D-CT. This project aims to optimize a clinically available 4D-MR pulse sequence to ac...
Authors: Akbar Anvari, Carnell J. Hampton, Melanie R. Piantino, Kai Yang
Affiliation: Levine Cancer Institute, Atrium Health
Abstract Preview: Purpose: To evaluate the effectiveness of angular correction factor for output stability on Mevion S250i Hyper scanning machine, which allows user to apply correction factors for output at selected ga...
Authors: Ndey Badjan, Chris Beasley, Issack Boru, Josh Joyner, Erica Owenby, Scott H. Robertson, Nicholas Said
Affiliation: Duke University Health System
Abstract Preview: Purpose:
To design MRI-visible laterality markers to boost patient safety by minimizing errors in laterality and subsequent procedures.
Methods:
The markers were made using commercially avail...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Lauren E Henke, Rojano Kashani, Christian Erik Petersen, Alex T. Price, Atefeh Rezaei, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: CBCT is subject to more artifacts due to increased photon scatter, especially in areas of increased tissue heterogeneities compared to fan-beam CTs (FBCTs). Improved imaging panels combined w...
Authors: James M. Balter, Alexander Moncion, Ikechi S Ozoemelam
Affiliation: University of Michigan
Abstract Preview: Purpose: Sequential dual-energy cone beam computed tomography (DE-CBCT) integrated with an online adaptive platform could potentially improve soft tissue visualization for more accurate anatomical del...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Early-stage NSCLC patients undergoing SBRT often die due to intercurrent illnesses. However, prediction of overall survival (OS) remains crucial due to the risk of disease recurrence. This st...
Authors: Daisuke Kawahara, Yoichi Watanabe
Affiliation: Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, University of Minnesota Medical School
Abstract Preview: Purpose: Combination therapies with immunotherapy (IT) and radiotherapy (RT) are widely used, but the optimal IT timing is unclear. This study leverages a computational cellular automaton (CA) model, ...
Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose:
MR-guided adaptive radiation therapy (MRgART) is transforming clinical workflows, requiring fast, accurate organs-at-risk (OARs) contouring. While deep learning auto-segmentation (DLAS) of...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: Ali Ajdari, Thomas R. Bortfeld, Christopher Bridge, Gregory Buti, Marcela Giovenco, Fredrik Lofman, Gregory C. Sharp, Helen A Shih, Tugba Yilmaz
Affiliation: Massachusetts General Hospital, RaySearch Laboratories, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: Defining radiation target volumes with accurate integration of the neuroanatomy is one of the major difficulties in designing glioma treatments. We developed a deep learning network for norma...
Authors: Qihui Lyu, Javier Caravaca Rodriguez, Youngho Seo, Ke Sheng, Jingjie Yu
Affiliation: University of California San Francisco, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Simultaneous broad-energy imaging is critical for many theragnostic applications, but the current Single-Photon Emission Computed Tomography (SPECT) can only image low energy photons with ...
Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...
Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler
Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC
Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...
Authors: Logan M. Bateman, Xu Cao, Jonathan T. Elliott, Lillian A. Fisher, Ida Leah Gitajn, Xinyue Han, Eric R. Henderson, Shudong Jiang, Jessica M. Sin, Yue Tang
Affiliation: Dartmouth College, Dartmouth-Hitchcock Medical Center
Abstract Preview: Purpose: Adequate tissue perfusion is essential for fracture healing and infection prevention, as it supplies oxygen, nutrients and antibiotics to the injury area. However, current methods of assessin...
Authors: Wesley A. Belcher, Robert A. Corns, Jae Won Jung, Matthew S Peach, Swarup Sharma
Affiliation: The University of North Carolina at Chapel Hill, East Carolina University Brody School of Medicine
Abstract Preview: Purpose: GammaTiles are a novel intracranial brachytherapy approach designed to directly deliver radiation therapy to residual or recurrent brain tumors following resection. Despite their promising th...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Gantry motion and patient breathing during a breast cone beam CT (bCBCT) scan is one of the major challenges for microcalcification (ÎŒCalcs) detection. By deploying a large number of individu...
Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Gagandeep Saini, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study examined the impact of varying the pitch factor in hippocampal-avoidance whole-brain (HP-WB) radiotherapy treatments, utilizing the newly introduced VOLO Ultra optimization for Hel...
Authors: Maya Ataya, Clint Bahler, Ramotallah Dami Jubril, Michael Koch, Oluwaseyi Oderinde, Mark Tann
Affiliation: Purdue University, epartment of Urology, Indiana University School of Medicine, Department of Urology, Indiana University School of Medicine, Department of Radiology and Imaging Sciences, Indiana University School of Medicine
Abstract Preview: Purpose:
To investigate racial differences in the detection of biochemical recurrence (BCR) using 68Ga-PSMA-11 PET/CT, known for its improved sensitivity and specificity in patients after radical p...
Authors: Clint Bahler, Ruchika Reddy Chimmula, Harrison Louis Love, Oluwaseyi Oderinde, Courtney Yong
Affiliation: Purdue University, Department of Urology, Indiana University School of Medicine, Advanced Molecular Imaging in Radiotherapy (AdMIRe) Research Laboratory, School of Health Sciences, Purdue University
Abstract Preview: Purpose: Prostate cancer (PCa) is a common malignancy in men, and predicting biochemical recurrence (BCR) is crucial for guiding treatment decisions. Integrating multimodal data, including clinical, i...
Authors: Nicholas Carlson, Joel J. St-Aubin
Affiliation: University of Iowa Hospitals and Clinics, University of Iowa
Abstract Preview: Purpose: To establish baselines metrics and determine longitudinal accuracy and reproducibility of Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) values for a 1.5T Elekta Un...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: Michalis Aristophanous, Laura I. Cervino, Maria F. Chan, Puneeth Iyengar, Hsiang-Chi Kuo, Nancy Y Lee, Xiang Li, Seng Boh Gary Lim, Usman Mahmood, Jean M. Moran, Jason Ocana
Affiliation: Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To determine the limits of iodine concentration detection (LOD) and quantification (LOQ) in dual-energy computed tomography using a 3D printed phantom while considering different background, ...
Authors: Molokotima Kekana, Dennis S. Mackin, Stephen W. Peterson, Jerimy C. Polf
Affiliation: Department of Physics, University of Cape Town, M3D, Inc, The University of Texas MD Anderson Cancer Center, Houston
Abstract Preview: Purpose: To study the imaging characteristics of a prototype prompt gamma (PG) imaging system consisting of multiple rotating Compton cameras (CC).
Methods: The prototype CC imaging system is c...
Authors: Liu Hong, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose: During treatment delivery on TrueBeam platform 2.7, Triggered Imaging (TI) enables kV images acquisition at regular intervals and Auto Beam Hold (ABH) provides beam pausing if the target is m...
Authors: Ananta Raj Chalise, Matthias K Gobbert, Hajar Moradmand, Sina Mossahebi, Stephen W. Peterson, Jerimy C. Polf, Lei Ren, Ehsan Shakeri, Vijay Raj Sharma, Jie Zhang
Affiliation: University of Maryland School of Medicine, University of Maryland Baltimore County, University of Maryland, University of Maryland, Baltimore County, University of Maryland, School of Medine, Department of Physics, University of Cape Town, M3D, Inc
Abstract Preview: Purpose: We are developing a novel Compton Camera (CC) system mounted orthogonally on the treatment nozzle for prompt gamma (PG) imaging-based proton range verification during treatment. This study in...
Authors: J. Daniel Bourland, Christina K Cramer, Justin M. Napolitano, James D. Ververs
Affiliation: Wake Forest University School of Medicine
Abstract Preview: Purpose:
Brain metastases (BM) can be treated with linear accelerator (LINAC)-based stereotactic radiosurgery (SRS). Treatment planning for this modality has evolved over time; treatment plans typi...
Authors: Emily Hansen, Alois M. Ndlovu, Niara Rowe, Roland Teboh
Affiliation: Hackensack University Medical Center
Abstract Preview: Purpose: The accuracy of SCINTIX biology-guided radiotherapy (BgRT) on the RefleXion X1 is dependent on the correct alignment of the isocenter between all subsystems, including setup lasers, kV imagin...
Authors: Jorge De La Cerda, Andrew Joseph Fanning, Tianzhe Li, Xiaofei Liang, Grace Murley, Mark Pagel, William Schuler, Renee Tran, Shuo Wang, Su-Min Zhou
Affiliation: University of Wisconsin Madison, University of Nebraska Medical Center, University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Electron paramagnetic resonance imaging (EPRI) can be used to image partial pressure of oxygen (pO2) in tumor models. The goal of this study is to develop an Oxygen Enhanced EPRI protocol to ...
Authors: Stewart J. Becker, Andrew Genuit, Mariana Guerrero, Yannick P. Poirier
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To introduce an additional quality assurance step to prevent human error in vial mix-ups during Yttrium-90 (Y90) radioembolization by verifying the local assay at the time of delivery. We pro...
Authors: Ryan Alden, Tithi Biswas, Kaushik Halder, Felix Maria-Joseph, Michael Mix, Rihan Podder, Tarun Kanti Podder
Affiliation: SUNY Upstate Medical University, IIT-Roorkee, University of Florida
Abstract Preview: Purpose: Radiomics feature-based model for predicting distant recurrence can potentially provide critical insight for clinical decision-making and assistance in treatment strategies. This study focuse...
Authors: Hania A. Al-Hallaq, Duncan Henry Bohannon, Chih-Wei Chang, Anees H. Dhabaan, Vishal Dhere, H Scott McGinnis, Pretesh Patel, Sagar Patel, Keyur Shah, Xiaofeng Yang, Jun Zhou
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Two-fraction proton SABR is an attractive alternative to brachytherapy for localized prostate cancer. However, potential interfractional anatomical changes necessitate online adaptation, espe...
Authors: Ruiming Chen Edmondson, Darwin Abraham Garcia, James A. Kavanaugh, Joseph John Lucido
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Characterize the dose response and reproducibility of a low-dose film for 6 MV photon beam and assess the filmâs energy dependence between kV and MV energies.
Methods: A single 8âx10â LD-V...
Authors: Victoria Susan Ainsworth, Stephen M. Avery, Serhii Brovchuk, Thomas Brown, Sean A. Dresser, Matthew D. Goss, Viktor M. Iakovenko, Kelly Kisling, Nataliya Kovalchuk, Robert F. Krauss, Wilfred F. Ngwa, Jatinder R. Palta, Julie A. Raffi, Peter Allan Sandwall, Natalka Suchowerska, William Swanson, Shada J. Wadi-Ramahi, Ruslan Zelinskyi
Affiliation: Allegheny Hospital, Johns Hopkins University, Virginia Commonwealth University, Stanford University, O.O. Shalimov National Institute of Surgery and Transplantology, Department of Radiation Oncology, UT Southwestern Medical Center, School of Physics, The University of Sydney, MaineHealth, University of California, San Diego, Duke University, Emory University, University of Pennsylvania, University of Pittsburgh Medical Center, Medical Physics Department, Medical center of Yuriy Spizhenko, OhioHealth, University of Massachusetts Lowell, St. Francis Hospital
Abstract Preview: Purpose: The AAPM International Council, in collaboration with Help Ukraine Group (HUG) and Ukrainian Association of Medical Physicists (UAMP), developed a novel hybrid year-long training course to as...
Authors: Christopher S. Melhus, Elizabeth Meyer, Cassandra Stambaugh
Affiliation: Tufts Medical Center
Abstract Preview: Purpose: To investigate the clinical treatment planning parameters that impact patient-specific quality assurance (PSQA) passing rates for hippocampal avoidance whole brain (HAWB) treatment plans.
...
Authors: Ahad Ollah Ezzati, Xiaoyu Hu, Xun Jia, Youfang Lai, Kai Yang, Yuncheng Zhong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Massachusetts General Hospital, Johns Hopkins University
Abstract Preview: Purpose: Contrast-enhanced breast cone-beam computed tomography (bCBCT) provides high-resolution, 3D imaging of breast tissues with improved differentiation between normal and abnormal tissues. Curren...
Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...
Authors: Sina Mossahebi, Pouya Sabouri, Kayla Schneider, James W Snider
Affiliation: University of Maryland School of Medicine, Proton International, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
Conventional patient-specific QA (PSQA) for intensity-modulated proton therapy (IMPT) requires extensive measurements, straining resources in single-room proton centers. This study evaluat...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...
Authors: Rico Castillo, Katherine Gonzalez, Casey C. Heirman, Kyle J. Lafata, Casey Y. Lee, Xiang Li, Yvonne M Mowery, Yvonne M Mowery, Daniel Murphy, Allison Pittman, Ashlyn G. Rickard
Affiliation: Duke University, Department of Radiation Oncology, Duke University, University of Pittsburgh
Abstract Preview: Purpose: To evaluate the ability of a deep learning model to identify pathomic features in lymph nodes of preclinical head and neck squamous cell carcinoma (HNSCC) models as surrogates for predicting ...
Authors: Minsong Cao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: N/A...
Authors: Madhava Aryal, James M. Balter, Yue Cao, Daniel T Chang, Kyle Cuneo, Joseph R. Evans, Theodore Lawrence, John Rice, Randall K. Ten Haken, Lise Wei
Affiliation: University of Michigan, Department of Radiation Oncology University of Michigan
Abstract Preview: Purpose: This study aims to identify predictors of global liver function change measured by albumin-bilirubin (ALBI) score following stereotactic body radiation therapy (SBRT) in hepatocellular carcin...
Authors: Jeffrey Andrews, Nathan E. Becker, Juanita Crook, Andrew Jirasek, Matthew Jonathan Muscat
Affiliation: UBC, BC Cancer Agency, BC Cancer
Abstract Preview: Purpose: To map dosimetry and imaging information to ultrasound and multi-parametric magnetic resonance (mpMR) guided trans-perineal core-needle biopsies, performed during two-fraction prostate high-d...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere
Affiliation: University of Chicago
Abstract Preview: Purpose: We assess two multi-measurement acquisition schemes for material decomposition with x-ray phase-contrast imaging (XPCI); demonstrating for the first time that multi-distance imaging can match...
Authors: Ziqi Gao, Lei Xing, Siqi Ye, S. Kevin Zhou
Affiliation: Department of Radiation Oncology, Stanford University, University of Science and Technology of China (USTC)
Abstract Preview: Purpose: To address the challenge of high memory usage in volumetric cone-beam CT (CBCT) imaging, we propose a method that combines joint reconstruction and super-resolution for sparsely sampled CBCT ...
Authors: Andrew Alexander, Brecca Bettcher, Bradley T Christian, Jose Guerrero-Gonzalez, Steven Kecskemeti, Lisette LeMerise, Max McLachlan, Andrew McVea, Matthew Zammit
Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center
Abstract Preview: Purpose: Individuals with Down syndrome (DS) develop Alzheimerâs Disease (AD) with very high prevalence (>90%). Neuropathology includes amyloid plaque (AÎČ) accumulation, followed by neurofibrillary ta...
Authors: Liang Cui, Xingyu Lu, Hang Shang, LingHong Zhou
Affiliation: Southern Medical University
Abstract Preview: Purpose: This study examines how varying dose rates of radiotherapy impact normal tissues outside the target area and analyzes the protective effects and regulatory mechanisms of ultra-high dose rate ...
Authors: Ali Ajdari, Alice Bondi, Thomas R. Bortfeld, Gregory Buti, Xinru Chen, Zhongxing Liao, Antony John Lomax, Ting Xu
Affiliation: The University of Texas MD Anderson Cancer Center, Department Of Radiation Oncology, Massachusetts General Hospital (MGH), Massachusetts General Hospital & Harvard Medical School, Paul Scherrer Institut, ETH Zurich
Abstract Preview: Title: Addressing Imaging and Biomarker-driven Uncertainty in Machine Learning-based Radiotherapy Outcome Prediction
Alice Bondi, Gregory Buti, Antony Lomax, Thomas Bortfeld, Xinru Chen, Ting Xu, Z...
Authors: Michael M Folkerts, Miriam Krieger, Pierre Lansonneur, Gerard Paquet, Petar Penchev, Christoph Schuy, Yuri Simeonov, Uli Weber, Klemens Zink
Affiliation: GSI Helmholtzzentrum fuer Schwerionenforschung, Institute of Medical Physics and Radiation Protection (IMPS), University of Applied Sciences, Varian Medical Systems
Abstract Preview: Purpose:
Ultra-high dose-rate proton irradiation may spare the healthy tissue (FLASH-effect). The 3D-range-modulator (3D-RM) method reduces the treatment time compared to conventional IMPT and can ...
Authors: Sam Beddar, Brett Bocian, David B. Flint, Benjamin Abraham Insley, Patrick James Jensen, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Reza Reiazi, Gabriel O. Sawakuchi
Affiliation: University of Miami, MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Empyrean Medical Systems, UT MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The Harrison-Anderson-Mick (HAM) applicator is an Ir-192 High-Dose-Rate (HDR) intraoperative radiotherapy device. It features a silicone body with embedded catheters that guide the Ir-192 sou...
Authors: Eujin Chan, Christopher Colyer, Leon F Dunn, Jonathan Dunning, Michael Grace, Onno Kamst, Alex Livingstone, Thulani Nyathi, Vladimir Sashin, Philip Satory, Hilmar Schachenmayr, Brindha Subramanian, Lindsay J. Tremethick, Luke Webb
Affiliation: GenesisCare
Abstract Preview: Purpose: The purpose of this work is to outline the methodology and results from the implementation of a 3D recalculation software to replace IMRT/VMAT PSQA measurement across a large, networked radio...
Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami
Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Sarah E. McKenney, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose:
While wide coverage (160 mm) CT scanners can image whole organs (e.g. heart, brain, kidneys, etc.) in one axial scan, the peripheral regions of the field of view (along z) suffer from cons...
Authors: Houssam Abou Mourad, Christopher Ackerman, Stephen Adler, Kirk Aduddell, Muhammad K. Afghan, Hamid G. Aghdam, Diego Aguilar, Kang-Hyun Ahn, Francis Ai, Hua Ai, Ray Anthony Aikens, Manik Aima, Victoria Ainsworth, Erfan Akbari, Blessing Akinro, Rani Al-Senan, Khalid Alabbasi, Sam Alam, Daniel Alexander, Mohammed H. Aljallad, Mazin T. Alkhafaji, Ahmad K. Alkhatib, Scott J. Alleman, James Logan Allen, Ibtisam Almajnooni, Tiba Alnaqshabandi, Murat Alp, Stephen J. Amadon, Riska Amilia, Ala Amini, Shiho Amster, Mason R. Anders, Erin Angel, Ledi Anggara, John A. Antolak, Debora Antonio, Felicity Appiah, Haiqa Arain, Lahcen Arhjoul, Ali V. Aritkan, Muhammad Arshad, Mark E. Artz, Nathan S. Artz, Frank A Ascoli, John R. Ashburn, Benjamin Astarita, Masakazu Atsumi, Rex G. Ayers, Tara M. Bachman, Nina L. Bahar, Bing Bai, Michael J. Bailey, Chris Baird, Mohammad Bakhtiari, Andrew J. Ballesio, Isabel Balvoa, Qinan Bao, Jeffrey J. Barbarits, Joseph Barbiere, Philip C. Bardos, Gary T. Barnes, John C. Barrett, Divya Bartley, Steven J. Bartolac, Robert Barton, Christopher P. Bass, Loni Bates, Alan Baydush, John E. Bayouth, Stephen Beach, Kevin Beaudette, Kaelyn Becker, Natalie A. Beckmann, Colleen Beer, Sepideh Behinaein, Jake M. Bell, David M. Bellezza, Maria R. Bellon, Ahmed Benelfassi, Stephanie Louise Bennett, Todd Bernath, Kate Bevins, Nicholas B. Bevins, Brian J. Bismack, David Blaich, Anthony P. Blatnica, Joseph W. Blickenstaff, Steven Blum, Maggie Bobbett, Dayna Bodensteiner, Daniel Boedeker, Robert C. Boggs, Jason D. Bond, Sjirk N. Boon, Jennifer M. Borsavage, Ryan J. Bosca-Harasim, Ryan J. Bosca-Harasim, Satya R. Bose, Todd Bossenberger, Cristina Boswell, Djamal Boukerroui, Christopher M. Bowen, Aaron Brammer, Rich Brancaleoone, Eric Brass, Luis Bravo, William Breeden, Christina Breeze, Eric E. Brost, Justin L. Brown, Karen L. Brown, Marissa Brown, Norman Lee Brown, Payton Brown, Patrick V. Brunick, Ryan Brunkhorst, Gwendolyn P. Brunner, Camelia E. Bunaciu, Maria Bunta, Olwen Burton, Karim Butalag, Priscilla F. Butler, Angela Cagwin, Jeffrey L. Campbell, Warren G. Campbell, Tyler Cantrell, Xu Cao, Yanan Cao, Peter F. Caracappa, Amanda M. Caringi, Joe Caron, Joshua Carter, Kenneth W. Cashon, Sarah Castillo, Everett Cavanaugh, Suran Chae, Abhi Chakrabarti, PhD, Philip Chan, Jina Chang, Sha X. Chang, Youssef M. Charara, Pierre E. Charpentier, Priyanka Chaudhary, Senthamil Selvan Chelliah, Chen Chen, Doris Chen, Kuan Ling Chen, Max Chen, Mingyue Chen, Mu Chen, Xinan Chen, Yie Chen, Yong Chen, Caroline Cheney, Shyh-Shi R. Chern, Stephen Thomas Chesser, Kin Man Cheung, Pai-Chun Melinda Chi, Yuwei Chi, Omar Chibani, Hung Ching, Gwi Ae Cho, Jongmin Cho, David Choi, Wing Yan Choi, Nitish Chopra, Daniel Christ, Olav I. Christianson, Emmanuel Christodoulou, Heeteak Chung, Sophia Claudio, Arely Clavel, William J. Clouse, Gilad Cohen, Michael S. Cohen, Vladimir Collantes, Jason Collier, Jacob Collins, Daria C. Comsa, Charles Conduah, Virgil N. Cooper, Anita M. Corrao, Frank D. Corwin, Mihaela Cosma, Ben Coull-Neveu, Mary K. Cox, Daniel F. Craft, Steven D. Crawford, Troy M. Crawford, Charles E. Creagh, Beatrice Croteau, Camille Crumbley, Wilbert F. Cruz, Guoqiang Cui, J. Adam M. Cunha, Scott Cupp, Bruce H. Curran, Jordan McCauley Cutsinger, Alita D Almeida, Harold DSouza, Nana Dabo-Akoteng, Robert Dahl, Shaun W. Dahl, Ghayath Dakkouri, Malek Daneshvarnezhad, Mylinh Dang, Matt Daniels, George M. Daskalov, David A. Davenport, Amanda Davidek, Scott E. Davidson, Maria De Ornelas, Dylan A. DeAngelis, Mike Deady, Daniel Dean, Savannah Decker, Savannah Decker, Michael Delafuente, Omer Demirkaya, Logan Dempsey, Marc Dennis, Viv Dennis, Dana Derby, Garron A. Deshazer, Veronique Destombes, Ajaya K. Devabhaktuni, Suneetha Devpura, James A. Deye, Shalmali Dharmadhikari, Dominic J. DiCostanzo, Richard V. DiPietro, Emily Diller, Lei Ding, Nayha V. Dixit, Charles Dodge, David N. Dodoo Amoo, Shana Donchatz, Lei Dong, Elangovan Doraisamy, Jennifer E. Dorand, Sarah Driver, Jiayi Du, Michael Duax, Ibrahim M. Duhaini, Ibrahim Duhaini, Kristen Duke, Richard Dunia, Leon Dunn, Shannon R. Durfee, Brittany Earl, Behzad Ebrahimi, Colton Eckert, Hisham Elasmar, John G. Eley, Abdelhamid Elfaham, David C. Ellerbusch, Scott J. Emerson, Sara Endo, David Erickson, Freddy Escorcia, Caroline Esposito, Patrice Essien, Adam Evearitt, Benjamin Fahimian, Liliosa C. Fajardo, Kevin Fallon, Guoqing Fan, Jiahua Fan, Mingdong Fan, Pei Fan, Bing Fang, Jian Fang, Yile Fang, Marc A. Felice, Ye Feng, Michele Sutton Ferenci, Philippe Feru, Jade Alecia Fischer, Aaron Fishbein, Caitlyn M. Fitzherbert, Damian Fondevila, Grant Fong, Robert Wesley Foster, Luke Fourie, Jeffrey Brian Fowlkes, Alexandre Franca Velo, D. Jay Freedman, Ronald W. Frick, Jie Fu, Samuel Fulton, Kamalakar Gaddam, Justin D. Gagneur, Mariana Gallo, Mariana Gallo, David Gammel, Robert G. Gandy, Junfang Gao, Yiming Gao, Victor L. Garcia, Michael Garcia-Alcoser, Jeffrey Garrett, Steven Anthony Gasiecki, Keith Gatermann, Avinash Gautam, Bhoj Gautam, Olivier Gayou, Andrew J. Gearhart, Paul B. Geis, Renil B. George, David P. Gierga, Robert Gilliam, James Giltz, Eric L. Gingold, Frederic Girard, Garth Gladfelder, Sharon Glaze, Brendan K. Glennon, Steven P. Glennon, Guy Godwin, David Lloyd Goff, Lisa M. Goggin, Daniel Goldberg-Zimring, Edward Joseph Goldschmidt, Ehsan Golkar, Angel Gomez, Jason Gong, Manish K. Goyal, Frank Graeff, Royce L. Gragg, Jonathan Gray, Alexander D. Green, Olga L. Green, Andrew Christopher Greene, Travis Greene, Jared Grice, Kevin T. Grizzard, Suveena Guglani, Jeffrey B. Guild, Patrick P. Guo, Sandesh Gupta, Megan Gute, Jonathan Ha, Rachael L. Hachadorian, Christopher Haddad, Lubomir Hadjiiski, Scott W. Hadley, Tomoe Hagio, Kelsey Hall, Logan P. Hall, Klaus A. Hamacher, Amineh Hamad Khatib, Amineh O. Hamad Khatib, Brian R. Hames, Carnell Hampton, Samuel S. Hancock, Robyn S. Handschuh, Jeremy Hansen, Paul Harden, Joseph Harms, Daniel P. Harrington, Carley Harris, Jamie Marie Harris, Jennifer Hart, Richard P. Harvey, Jeremy Hawk, Naoki Hayashi, Maria Laura Haye, Katherine Hazelwood, David Hearshen, Bret H. Heintz, Adam Henry, Frank William Hensley, Michael Chris Hermansen, Marissa Hernandez, Nadia Hernandez, Dayadna Hernandez Perez, Sarah Hetherington, Emily Hewson, Maynard High, Brian P. Hill, Charles B. Hill, Yunsil Ho, Simeon Hodges, David M. Hoeprich, Michael N. Hoff, Robert F. Hoffman, Russell Holden, Clay Holdsworth, Scott Hollingsworth, John R. Holmes, Steve Holmes, Neal S. Holter, Thomas M. Holtschneider, Amirul Hoque, Sabbir Hossain, Tyler S. Howlin, Andrew Robert Hoy, An Ting Hsia, Hao-Yun Hsu, David Hu, Tom C. Hu, Yu-Chi Hu, Long Huang, Mi Huang, Joshua Hubbell, Michael J. Huberts, Julie C. Hudson, Geoffrey Hugo, Donglai Huo, Justin D. Hurley, Martina H. Hurwitz, Mohammad NASEEM Hussain, Andrew Hwang, Ui-Jung Hwang, Joe Ianni, Geoffrey Ibbott, Khalil Ibrahim, Ileana Iftimia, Mohammad Islam, Oleksandra Ivashchenko, Keyvan Jabbari, Joshua Jackson, Joshua Jackson, Ferenc Jacso, Mary Ellen Jafari, Karim Jaffer, Amit Jain, Ngoneh Jallow, Sachin R. Jambawalikar, Joshua A. James, Sunyoung Jang, Desiree Jangha, Tomaj Javidtash, Jun-Hsuang Jen, Peter Jenkins, Todd P. Jenkins, Andrew R. Jensen, Mads Lykke Jensen, Hosang Jin, Bowen Jing, Danielle Marie Johnson, Joshua D. Johnson, Holly Johnston, Kevin Jones, Badal R. Juneja, Nikhil Sriram Kabilan, Robert Kaderka, Jaclyn Kain, Faraz Kalantari, Maduka M. Kaluarachchi, Ali Kamen, Amrit Kaphle, Alireza Kassaee, Saravjeet Kaur, Vaiva Kaveckyte, Linda A. Kelley, Katelyn Kelly, Kathryn Elise Bales Kelly, Delsin B. Khan, Om Khanal, Maksud Khatri, William Steadman Kiger, Bryan Kim, Jong Oh Kim, Sangroh Kim, Sophia Kim, Brian W. King, Erica Kinsey, Assen S. Kirov, Marc T. Kleiman, Matic Knap, Robert J. Kobistek, Inger-Karine Kolkman-Deurloo, Erika Kathryn Kollitz, Dramane Konate, Xiang Kong, Walter Kopecky, Sandra Kos, Nataliya Kovalchuk, Shane Krafft, James A. Kraus, Robert Krauss, Deae-eddine Krim, Serguei Kriminski, Kerry T. Krugh, Lichung Ku, Esra Kucukmokroc, Randi Kudner, Andrew T. Kuhls-Gilcrist, Antti Juhani Kulmala, Akila D. Kumarasiri, Zacariah E. Labby, Taylor Lackey, Edcer Jerecho Laguda, Thang Lam, Michael A. S. Lamba, Kara Lambson, Laurel Zenaida Larramendi, Andy D. Lau, Wolfram Laub, Tyler Laugh, Robert P. Laureckas, Donald Laury, Patricia Lavey, Ashlie Laydon, Adam LeVay, Brandon Lee, Brian Lee, Dong-Chang Lee, Ji Hyun Lee, Jui-Min Lee, Bryan Lemieux, Matthew Lesher, Nicole Leslie, Etienne Lessard, Trish Lewis, Alan Li, Alexander N. Li, Hui Li, Jenny Li, Jiaxin Li, Qiongge Li, Taoran Li, Xiang Li, Yanlong Li, Zisheng Li, Xing Liang, Yun Liang, Chien-Yi Liao, Karisa Liaw, Sung-Yen Lin, Tiffany Lin, Holly M. Lincoln, Lin Ling, Chang Liu, Shaohua Liu, Yu Liu, Chih-Ming Mark Lo, Eric Lobb, Dilson Lobo, Virginia L. Lockamy, Lauren C. Long, Nelia S. Long, Troy Long, Michele Loscocco, Thomas Lowinger, Cynthia Lu, Minghui Lu, Winnie Lu, Yonggang Lu, Jianqiao Luo, Pei-Chin Luo, Xuhan Luo, Jan Luse, Daniel A. Lutterman, Dang Hoang Oanh Luu, Yulia Lyatskaya, Trina Lynd, Morgan Cervo Lyon, Chi Ma, Jingfei Ma, Tianjun Ma, Laurie Madden, Gregory E. Madison, Kurt Maffei, Michael J. Maffett, Nyasha G. Maforo, Dennise Magill, Emma Magness, Alphonso W. Magri, Dennis Mah, Usman Mahmood, Rebecca N. Mahon, Courage Mahuvava, Andrew D. Maidment, Gerassimos M. Makrigiorgos, Harish K. Malhotra, Kate Mallory, P. Scott Mange, Vivek Maradia, Jacob Marasco, Camilla Marino, Loren R. Marous, Wagner Marques, Craig M. Marsden, Edward I. Marshall, Jonathan Marshall, Caroline Martel, Colin Martin, Alejandro Martinez, Jeffrey P. Masten, Richard Mathew, Bobby Mathews, Anetia S. Matthews Jackson, Matthew R. Maynard, Joel R. McAllister, Rafe McBeth, James A. McCulloch, Kiernan T. McCullough, Keelin McGee, Kiaran P. McGee, Brian M. McGill, Christopher M. McGuinness, Robert McKoy, Steven M. McQuiggan, Lacey Medlock, Chirag D. Mehta, Nancy Meiler, Robert Meiler, Matthew A. Meineke, Caroline Melancon, Daniel S. Meleason, Carolyn Meltzer, Chunhua Men, Stephanie Merkl, Michael Merrick, Keith A. Michel, Georgeta Mihai, Ana Mihail, Devin A. Miles, Edward J. Miller, Elizabeth A. Miller, Ronaldo Minniti, Linda Minor, Filmon Misgina, Ajeet Kumar Mishra, Chad Mitchell, Drew P. Mitchell, Gregory S. Mitchell, Jessica Mitchell, Jacqueline Moga, Uwe Mollenhauer, Julien-Fabrice Ngoune Momo, Emi Mondragon, Nicholas Mongillo, Victor J. Montemayor, Scott Montgomery, Diego Luis Montufar Hidalgo, Mohammadamin Moradi, Serban Morcovescu, Jill Anna Moreau, Terrance Moretti, Toby Morris, Courtney K. Morrison, Alexander Albert Morrow, Jill Moton, Jonathon Mueller, Reshma Munbodh, Daniel W. Mundy, Daniela Murgulet, Scott A. Murphy, Benjamin C. Musall, Jana E. Musgrove, Samantha Musial, Yong Hum Na, Joel Nace, Paul Naine, Justin Napolitano, Vrinda Narayana, Ganesh Narayanasamy, Moulay Ali Nassiri, Muhammad Naveed, Richard D. Nawfel, Ritish Nedunoori, Aaron Nelson, Kristin J. Nelson, Aaron Nelson, MD, Neerajan Nepal, Emily Neubauer Sugar, Shree Neupane, David Newey, Mark Newpower, Susan Ng, Bau H. Nguyen, Daniel J. Nicewonger, Xingyu Nie, Ethan Nikolau, Kevin D. Nitzling, Kai Niu, John M. Noll, Prashanth K. Nookala, Khalid Noori, James T. Norweck, Hamidreza Nourzadeh, Jessica L. Nute, Sebastiaan Nysten, Kevin OGrady, Ceferino Obcemea, Keith Ober, Jacqueline Ogburn, Timilehin Ogunbeku, Mina Okello, Brian Olson, Martin Keane Ongeti, Savannah Orrill, Joseph Ott, Bahadir Ozus, Jan Pachon, Alexis Paige-Glenn, Jason Paisley, Farideh Pak, Randahl C. Palmer, Kiran Pant, Virginia Pappas, Abby Pardes, So-Yeon Park, Alexis Parker, Karla Parker, Homayon Parsai, Tommy O. Parsons, Pankaj Patel, Amy Patrick, Johnlly G. Pattaserial, Lindsey M. Patton, Taylor J. Patton, Nava R. Paudel, Timothy John Paul, Colin Paulbeck, Olga V. Pen, Cheng Peng, Yuanlin Peng, Carmelo Perez, Dominik PeruĆĄko, Alexander Pevsner, Douglas Pfeiffer, Melanie Piantino, Daniel Piatigorski, Rajesh Pidikiti, Natalie Piechowska, Greg Pierce, Tina Pike, Donika Plyku, Robert Pohlman, Mariela Adelaida Porras-Chaverri, Subechhya Pradhan, Guillem Pratx, Chris Proctor, Alexander Pryanichnikov, Diane Pugel, Yue Qiu, Adam C. Quinton, Todd Racine, Andrea Radine, Dustin K. Ragan, Balasubramanian Rajagopalan, Kishore Rajendran, Eric V. Ramirez, Mehdi Ramshad, Vijay K. Rana, Brianne Raulston, Amy K. Readshaw, Hailey Reaux, Ian Reineck, Xuemin Ren, Meral L. Reyhan, Davenport Ria, Matthew J. Riblett, Kenneth M. Richardson, Rebecca F Richardson, Matthew Richeson, Ashlyn Rickard, Adam Riegel, Lynn N. Rill, Miguel A. Rios, E. Russell Ritenour, Scott P. Robertson, Marthony L. Robins, Rebecca Robinson Rey, Steve Rodney, Priscila Rodrigues, Edgardo Rodriguez, Tino Romaguera, Emilie Roncali, Joseph E. Roring, Alison R. Roth, Lawrence N. Rothenberg, Nick Rothwein, Kricia Emilia Ruano Espinoza, Damian DG Rudder, Donald R. Ruegsegger, Erwin W. Ruff, Brandon J. Russell, Frederick Rustad, Narayan Sahoo, Jonathan H. Saleeby, Habeeb H. Saleh, Flavio Salinas Aranda, Steffen Sammet, Daniel Sandoval, Aman Sangal, Joseph P. Santoro, MaĂra Santos, Alexis Marie Sanwick, Milind Sardesai, Vikren Sarkar, Duminda Satharasinghe, Jessica L. Saunders, Carmen Sawyers, Sarah B. Scarboro, James Scheuermann, Colleen G. Schinkel, Dale Schippers, Joshua William Schlegel, David J. Schlesinger, Charles Ross Schmidtlein, Erich Schmitz, Jose Schneider, Erich A. Schnell, Lisa Schober, Leah Schubert, Michelle L. Schwer, James Seekamp, Jennifer Seger-Paisley, J. Anthony Seibert, Balaji Selvaraj, Raj N. Selvaraj, Meredith A. Semon-Pomposelli, Lasitha Senadheera, Naima Senhou, Christopher F. Serago, Hananiel Setiawan, Shakil B. Shafique, Aarti Shah, Hina Shah, Alok Shankar, Ryan Shanks, Kritika Sharma, Sunil K. Sharma, Jennifer M. Shealy, Ron Sheen, Gina L. Shelton, Mohammad Ullah Shemanto, Zion Sheng, Andrew J. Shepard, Justin R. Sherman, Kaizhong Shi, Xiaolin Shi, J. Allen Shih, Taciana Soares Shiue, Deborah J. Shumaker, Noah Silverberg, Ramon Alfredo C. Siochi, Amogh Sirniirkar, Marlene Skopec, Michael G. Skowronski, Dana Smetherman, Erika Smith, Eileen Sneeden, Jesse Snyder, James C. So, Emilie Soisson, Nima Soltani, Kwang Hyun Song, Liang Song, Xiaoling Song, Jigar B. Soni, Yashvant C. Soni, Jagadeesh R. Sonnad, Michael A. Speidel, Michael P. Speiser, James D. Speitel, Tanya Spellman, Joseph Patrick Speth, Daniel J. Spitznagel, Sara T. St. James, Alexander Stanforth, George Starkschall, James Stebelton, James P. Steinman, Jonathan M. Stenbeck, Robin L. Stern, Patrick D. Stevens, Erika Stewart, Gary Stinnett, Sarah A. Strand, Keith J. Strauss, Kristen Stryker, Edward Sudentas, Kevinraj N. Sukumar, Orhan H. Suleiman, John L. Sullivan, Paul Robert Sullivan, Mei Sun, Peng Sun, Kumari Sunidhi, Jacob Sunnerberg, Elizabeth A. Swanson, William J. Swanson, Larry E. Sweeney, Sean Swiedom, Gregory Szalkowski, Katsuyuki Taguchi, MohammadAli Tajik-Mansoury, Reza Taleei, Derek Tang, Shengzhang Tang, Mahin Tariq, Jason S. Tavel, Neelima Tellapragada, Alexandra Tellez, Dawn Tellez, Juan Manuel Tellez, Xiaokun Teng, James A. Terry, Biniam Tesfamicael, Confex Test, Aapm Tester, Contex Tester, Namita Thakur, David J. Theel, Kathleen D. Thomas, Emily A. Thompson, Stephen K. Thompson, Daniela Thorwarth, Kevin Tierney, Anders Tingberg, Ragu S. Tirukonda, Robert A. Tokarz, Robert J. Tokarz, Naresh B. Tolani, Brian Tom, Shidong Tong, Ebrahim Torangan, Martin Tornai, Diana Tovmasian, Trung Tran, Bryan Traughber, Samuel Trichter, Sugata Tripathi, Petra Trnkova, Panagiotis Tsiamas, Ryan Tsiao, Haifeng Tu, Philip N Tubiolo, Jeff D. Turley, Adam Turner, PhD, DABR, Conner Ubert, Chibueze Zimuzo Uche, Vincent M. Ulizio, Gnanaprakasam Vadivelu, Hema Vaithianathan, Sunil Valaparla, Fabiola Vallejo Castañeda, Liesbeth Vancoillie, Matt Vanderhoek, Caroline Vanderstraeten, Nancy J. Vazquez, Linda A. Veldkamp, Trevor L. Vent, Anthony M. Ventura, Keith Ver Steeg, Irina Vergalasova, CHENG WANG, Christopher Waite-Jones, Matthew C. Walb, Reuben Waldron, Arlie Vester Walker, Jim Walsh, Alisa I. Walz-Flannigan, Cheng Wang, Helen H. Wang, Hui-Chuan Wang, Jiali Wang, Jian-xiong Wang, Kai Wang, Kyle Wang, Ning Wang, Yuntao Wang, Zhendong Wang, Zhixing Wang, Grace Ward, Sarah M. Way, Rachel L. Waymire, Melvin Weatherly, Charles Travis Webb, Lincoln J. Webb, Jia Wei, Wenbo Wei, Callie Weiant, Miriam S. Weiser, Eric M. Welch, Jered R Wells, Michelle C. Wells, S. Brock Westlund, Gerald A. White, John White, Darunee S. Whitt, David Wikler, Austin Wilkinson, Carly D. Williams, Mark Bennett Williams, Joshua M. Wilson, Keli C. Wilson, Nicholai Wingreen, Joseph Wishart, Alon Witztum, Katherine M. Woch Naheedy, Andy Wolf, Serkalem E. Wondimgezhu, Genevieve N. Wu, Wenhao Wu, Ye Wu, Yuxiang Xing, Li Xiong, Weijun Xiong, Xunyi Xu, Yan Xu, Tianyou Xue, Yanjie Xue, Girijesh K. Yadava, Derek Z. Yaldo, Kaiguo Yan, Yue Yan, Nathan E. Yanasak, Bowen Yang, Ray Yang, Xiaocheng Yang, Yun Yang, Yunze Yang, Bin Yao, Yuan (John) Yao, Anna N Yaroslavsky, Feng-Ju Yeh, Susanne Yerich, Michael V. Yester, Xiaofei Ying, Tekeste Yohannis, Tony Younes, Eyesha Younus, Jialu Yu, Justin Yu, Yan Yu, Pui Kuen Yuen, Joshua P. Yung, Steve Yuvan, Mehran Miron Zaini, Ramtin Zakikhani, Lee Anne Zarger, Merissa Zeman, Lisa Zent, Di Zhang, Dongqing Zhang, Hao Zhang, Jun Zhang, Lei Zhang, Lu Zhang, Maochen Zhang, Peng Zhang, Peng Zhang, Qingyun Zhang, Xin Zhang, Yi Zhang, Yinghui Zhang, Yongbin Zhang, Zhongwei Zhang, Bo Zhao, Xuandong Zhao, Yizhou Zhao, Weiping Zheng, Yi Zheng, Troy Zhou, Xiangzhi Zhou, Xiaohong Joe Zhou, Yuwei Zhou, Jin Zhu, Mingyao Zhu, Eric C. Zickgraf, John R. Zullo, Piotr Zygmanski, Leo van Battum
Affiliation: DTC Consultants, NL Health, Dartmouth Hitchcock Medical Center, ProCure Proton Therapy Center, Medical & Radiation Physics, Inc, Augusta University, Genesis Healthcare Partners, Michigan Medicine, Washington DC VA Medical Center, VA Medical Center, Mercy Southeast Hospital, Food And Drug Administration, University of Iowa, Advanced Radiation Physics Service, Inc, University of Pittsburgh, University of Wisconsin, Wellspan Health, Good Samaritan Hospital, Howard University Hospital, St. Mary's Memorial Health Center, Penn State Milton S. Hershey Med Ctr., New York Weill Cornell Medical Ctr, X-Ray Computations, Inc., US Navy, Penn State Health, Kelsey Seybold Clinic, Advocate Aurora, Fresno Cancer Center, Central Alabama Radiation Oncology, Riverside Methodist Hospital Ohio Health, Alliance Medical Physics, OCSRI, AAPM, University of Minnesota, University of Virginia Health System, PGIMER, Barrigel, Johns Hopkins Univ, Appex Physics Partners, BoxElder Research, University of Oklahoma Health Sciences Center, Sanford Roger Maris Cancer Center, Berkshire Medical Center, New York Weill Cornell Medicine, Mobimed Technologies, University of Chicago Medicine, Johns Hopkins Medicine, Maimonides Medical Center, Nuvance Health - Vassar Brothers, Crozer Keystone Health System, Karmanos/McLaren, Vanderbilt University, Panhandle Cancer Care Center, The University of Michigan, Piedmont Healthcare, Gamma Medical Physics LLC, Mississippi Baptist Medical Center, Astarita Associates Inc, Landauer Medical Physics, RPS Oncology, Zhejiang University, University of North Carolina School of Medicine, University of Kentucky HealthCare, Peninsula Regional Medical Center, Varian Advanced Oncology Solutions, New York Proton Center, Wake Forest University Medical Center, Rutgers Robert Wood Johnson Medical School, Tx Oncology, Lewis Hall Singletary Oncology Center (John D. Archbold Hospital), Medical Physics Services, University of New Mexico, UPMC Cancer Center, Medical Physics Solutions, LLC, ECU Health, Evercare Hospital Chattogram, Mercy Cancer Center, Sharp Grossmont Hospital, West Virginia University, Virginia Commonwealth University Medical Center, Thomas Jefferson University, Centennial Medical Physics, LLC, University of California, Davis, University of Miami, Varian, Inc., UAB Medical Center, Wellspan health, Cleveland Clinic Foundation, Procure Treatment Center, Retired FDA, Tufts Medical Center, Virginia Commonwealth University, Germantown Academy, Hartford Hospital, Cleveland Clinic Florida, Billings Clinic, Imalogix, University of Wisconsin - Madison, Dana Farber Cancer Institute, Massachusetts General Hospital, Johns Hopkins University, GenensisCare, VARIAN Siemens Healthineers, MedStar Washington Hospital, Illawarra Cancer Care Center, Duke Health, Corewell Health, Columbia University, Johns Hopkins, Baylor Scott & White Health, Ascension Saint Thomas Rutherford Hospital, Varian, a Siemens Healthineers company, Rabin Medical Center, Albany - Stratton VA, Florida Cancer Specialists at Tampa Cancer Center, Baylor St Lukes Medical Center, Baylor College of Medicine, Christiana Care Health System, West Physics, Mayo Clinic Arizona, Emory University, University of Pittsburgh Medical Center, Brigham and Women's Hospital, UCLA, CoxHealth, Starsino Medical Technologies Co Ltd, University of Utah Hospitals, Lahey Health Medical Center, Paul Scherrer Institute (PSI), Karmanos Cancer Institute, Radcom Associates, LLC, Ascension Wisconsin, The University of Alabama at Birmingham, Winter Park Cancer Center, Louisiana State University, UT Health San Antonio, Intermountain Health, Penn Medicine/Lancaster General Health, Elekta Xoft, University of KY HealthCare, Rutgers, Cancer Institute of New Jersey, Real Time Tomography LLC, Toronto Metropolitan University, UCSD, Dartmouth College, Ascension St. Thomas Rutherford hospital, City of Hope, Radiation Management Associates, Levine Cancer Institute, Atrium Health, Varian Medical Systems, Blount Memorial Hospital, Penn State University, Therapy Physics, Inc., Northwest Community Hospital, Duke University Medical Center, Advent Health, Miami Cancer Institute, Washington State Department of Health, Lantheus Medical Imaging, Chesapeake Potomac Regional Cancer Center, MRP Inc., University of Chicago, University of Tennessee Medical Center, Huntsman Cancer Institude, University of Utah, Oregon Health and Science University, Hutchinson Regional Medical Center, Winchester Medical Center, WellSpring Oncology, Medical School of East Carolina Univ, Weill Cornell Medical Center, UPMC Hillman Cancer Centers, Springfield Clinic, CaliberMRI, Inc., Prisma Health, Helen F. Graham Cancer Center, ChristianaCare, Upstate Medical Physics, PC, Loma Linda University Medical Center, Radpocket LLC, RayzeBio, St. Peter's Health Partners, MJS Medical Physics Inc., UCHealth, Astarita Associates, Image X Institute, School of Health Sciences, University of Sydney, Oregon Urology Institute, Seoul National University Hospital, GenesisCare, Reid Health, National Institutes of Health (NIH), Bayhealth Medical Center, Albany Medical College, Advocate Radiation Oncology, Rush, Krueger-Gilbert Health Physics, Sentara Healthcare, Accuray Incorporated, CTSI, RTI Group North America, University of Louisville, Thomas Jefferson University Hospital, NCI, West Physics Consulting, LLC, Boston Childrenâs Hospital, CHOP, Greater Baltimore Medical Center, Florida Cancer Specialist & Research Institute, Radformation, Texas Oncology South Austin Cancer Center, Mosaic Life Care Cancer Center, University of Virginia, CPDS, Ravenel Oncology Center, M Health Fairview, Torrance Memorial Medical Center, RJK Medical Physics, Inc., NYU Langone-Long Island, Trinity CancerCare Center, Bryn Mawr Hospital, Sanford Health, University of Michigan Health Systems, One Physics - Ohio Medical Physics Consulting, West Michigan Cancer Center, University Hospitals Cleveland Medical Center, Levine Cancer Institute/Atrium Health, Advanced Biophotonics Laboratory, University of Massachusetts Lowell, UConn Health, U.S. Nuclear Regulatory Commission, Wayne State University, University of Oklahoma Health Science Center, Houston Methodist Hospital, Varian, Arizona Center for Cancer Care, NIH Clinical Center, Stanford University, Hospital of the University of Pennsylvania, Peel Regional Cancer Center, Credit Valley Hospital, University of Alabama Birmingham, Lark Physics, Ackerman Cancer Center, Southern District Health Board, Milestone Medical Physics Group, UTHealth Houston McGovern Medical School, Rutgers University, West County Radiological Group, Mayo Clinic, Philips Healthcare, University of Vermont Medical Center, Novant Health at Presbyterian Medical Center, Harvard Medical School, Ratio Therapeutics, Naval Medical Center Portsmouth, University Colorado Denver, School of Medicine, Sutter Santa Cruz Radiation Oncology, Radiophysics Associates, Northside Hospital, SolutionHealth, University of Virginia Health Systems, Johns Hopkins School of Medicine, Austin Health, UPMC, St. Joseph Mercy Health System, Cancer Center of Hawaii, Centra Health, Aspekt Solutions, Winter Haven Hospital, Henry Ford Hospital System, Medical University of South Carolina, Maine Medical Center, Phoenixville Hospital, National Institutes of Health, Associated Medical Professionals, Gundersen Health System, St. Luke's University Health Network, Univesity of Victoria, Department of Radiation Oncology, Stanford University School of Medicine, Washington University in St. Louis, Queen's Medical Center, West O'ahu, Canon Medical Research USA, Inc., Robert Wood Johnson University Hospital, UVA Health System, Section for Biomedical Physics, Department of Radiation Oncology, University Hospital and Medical Faculty, Eberhard Karls University TĂŒbingen, Centennial Medical Physics, McLaren Cancer Institute, Cancer Care Group, Texas Oncology-Tyler, CTSI Oncology Practice Solutions, a varian company, Bank of Cyprus Oncology Centre, Columbus Regional Hospital, Central Florida Cancer Insititute, Texas Oncology - San Antonio, The Ohio State University, Stony Brook University, Greenwich Hospital, INOVA Schar Cancer Institute, Marsden Medical Physics Associates, Allegheny Health Network, Geisinger Health System, University of Maryland Medical System, Texas Oncology, Mount Sinai Medical Center, TrueNorth Medical Physics, Mallinckrodt Institute of Radiology, Washington University School of Medicine in St. Louis, Houston Methodist Hospital, Houston, TX, Martin Memorial Medical Center, Yale University School of Medicine, Comprehensive Cancer Centers of Nevada, ASR Institute for Cancer Care, Research & Rehabilitation, University of Louisville Brown Cancer Center, Jaeger Corporation, UC San Francisco, Inova Hospital at Fairfax, Upstate Medical Physics, Cedars-Sinai Medical Center, Brown University Health, Texas Oncology-Denton, Assarian Cancer Center, HCA Healthcare, San Diego State University, Cooper University HealthCare, LVeldkamp MedPhys Services, LLC, Morristown Medical Center, Atlantic Health System, OMPC Therapy, LLC & OMPC Diagnostic, LLC, Defense Health Agency, Radiation Oncology, Medical College of Wisconsin, UT Southwestern Medical Center, Kaiser Permanente Bellflower Medical Center, Roswell Park Comprehensive Cancer Center, University of Victoria, MD Anderson Cancer Center at Cooper, Siemens Healthineers, Monmouth Medical Center, Memorial Sloan Kettering Cancer Center, Ironwood Cancer & Research Centers, University of Cincinnati, School of Medical Sciences, Fujita Health University, University of Kentucky/UK HealthCare, University of California, San Francisco, Instituto Nacional do Cancer, Brazil, IBA Dosimetry GmbH, Westchester Medical Center, Ohio State Univ, Houston Methodist, Medical College of Wisconsin, Columbia University Medical Center, Department of Radiation Oncology, College of Medicine, University of Arkansas for Medical Sciences, UT MD Anderson Cancer Center, DFCI/BWCC south shore, Providence Cancer Center, Memorial Sloan-Kettering Cancer Center, American Association of Physicists in Medicine, Lynn Cancer Institute - Radiation Oncology, Renown Health, Purdue Univ, Beth Israel Deaconess Medical Center, Department of Radiation Oncology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Holy Family Hospital, OhioHealth, IBA Dosimetry, Memorial Hospital Gulfport, University of Florida, George Washington Univ, University of Cincinnati Medical Center, Hubbard, Zickgraf, & Broadbent, Accuray Inc, UVRMC, MIM Software, Massachusetts General Hospital and Harvard Medical School, Mem. Sloan Kettering Cancer Ctr, UF Health Proton Therapy Institute, California Medical Physics, Inc., Henry Ford Health, UPMC Hillman Cancer Center, Vanderbilt University School of Medicine, Saddleback Memorial Medical Center, Stony Brook University Medical Center, University of Pennslyvania, TOP Physics Consulting, Nuvance/Norwalk Hospital, Oregon Health & Science Univ, Brigham & Women's Hospital, University of Pennsylvania, McLaren â Greater Lansing, American Board of Radiology, Penn Medicine | Virtua Radiation Oncology, University of Tennessee, OneOncology, University of Colorado, Indiana University Medical Center, Stronach Regional Cancer Centre, Yale New Haven Health, Vanderbilt University Medical Center, Emory Healthcare / Winship Cancer Institute, Cape Fear Valley Radiation Oncology, Northwell Health, Sutter Health, Virginia Mason Medical Center, MUSC Health- Florence Medical Center, Departement of Radiation Oncology, Curie Institute, Paris, University of Michigan, MD Anderson Cancer Center, University of Alabama at Birmingham, Radiology Inc., Cedars Sinai Hospital, Roswell Park Cancer Institute, Duke University Health System, VA Hospital, DVA Medical Ctr., JFK Medical Center, Mount Sinai West, National Cancer Institute, Chung Nam National University Sejong Hospital, Indiana Univesity, AdventHealth Daytona Beach, Orlando Health, Clinical Research Institute HUS, Northwest Medical Physics Center, University of Pennsylvania, Penn Medicine, Kettering Health Network, Children's Mercy Kansas City, IBA, UMass Memorial Hospital, US Oncology, Kaiser Permanente Southern California Medical Group, The Queen's Health System, NewYork-Presbyterian, Miami Valley Hospital, Karlsruhe Institute of Technology, Piedmont Hospital, Accuray Inc., VARIAN - Advanced Oncology Solutions, GE Healthcare, Virtua Health, Northwestern Medicine Chicago Proton Center, CARO/Montgomery Cancer Center, Walter Reed National Military Medical Center, InterMountain Health Care, Englewood Hospital and Medical Center, Henry Ford Health System, Fluke Health Solutions, Texas Oncology, PA, Inova Alexandria Hospital, New Milford Hospital, Fox Chase Cancer Center, Radiation Therapy and Cancer Inst, Penn State College of Medicine, University of California San Francisco, Unity of Oncologic Therapy S.A., Canon Medical Systems USA, Kaiser Permanente, Baptist Health Paducah, Salina Regional Health, Centre d'Oncologie de la Cote Basque, Minneapolis Radiation Oncology, Coastal Carolina Radiation Oncology, Saint Francis Hospital, Advocate Christ Medical Ctr, Universidad de Costa Rica, CAMP, Blessing Hospital, Texas Oncology Cancer Ctr, CommonSpirit Health, Navy Medical Forces Atlantic, Regions Hospital, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Methodist Hospital, Champlain Valley Physicians Hospital, Mayo Clinic Jacksonville, OHSU, Promedica Health System, Arthur JE Child Comprehensive Cancer Centre, Rhode Island Hospital / Warren Alpert Medical, UPMC Pinnacle Health, Vassar Brothers Hospital, McLeod Regional Medical Center, RJ Tokarz MIRS, St. Francis Hospital, Astarita Associates, Inc., UC Davis Medical Center, Mount Nittany Medical Center, Covenant Radiation Center, National Institute of Standards and Technology, AdventHealth Orlando, St Helena Hospital, Icon Cancer Centre, University of Washington, Indiana University, TrueNorth Medical Physics LLC, Medstar Georgetown University Hospital, Harold Alfond Center for Cancer Care, MN Oncology, Jupiter Medical Center, GE HealthCare, Rochester General Hospital, Piedmont Health, Atrium Health, Minneapolis VA Health Care System, CentraCare Health System, OMPC Diagnostic LLC, Evergreen Health Medical Center, CAMC Cancer Center - Beckley, University of Kansas Medical Center, Avera McKennan, Cleveland Clinic, Louisiana Tech University
Abstract Preview: N/A...
Authors: Magdalena Bazalova-Carter, Ross I. Berbeco, James Day, Xinchen Deng, Chelsea Amanda Saffron Dunning, Dianne M. Ferguson, Matthew W. Jacobson, Toby Morris, Marios Myronakis, Jericho Daniel O'Connell, Fides Schwartz, Jainil Shah, Aaron Sodickson
Affiliation: Brigham and Womens Hospital, University of Massachsetts Lowell and Dana-Farber Cancer Institute Boston, Medical Physics Department, Medical School, University of Thessaly, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology, University of Washington, University of Victoria, Siemens Healthineers, Dana Farber/Brigham and Women's Cancer Center, Brigham and Women's Hospital
Abstract Preview: Purpose: While CT imaging has advanced with improved machine design, we propose further gains can be achieved by enhancing sensitivity to contrast agents. Current CT sensitivity is limited to 1% bismu...
Authors: Daniel O Connor, Mary Feng, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger, Jess E. Scholey, Ke Sheng, DI Xu, Wensha Yang, Yang Yang
Affiliation: UCSF, University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, University of San Francisco, Department of Radiology, University of California, San Francisco, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: The scanning time for a fully sampled MRI is lengthy. Compressed sensing (CS) has been developed to minimize image artifacts in accelerated scans, but the required iterative reconstruction is...
Authors: Md Mainul Abrar, Yujie Chi
Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington
Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Deep learning-based automatic medical image segmentation is increasingly employed in clinical practice, significantly reducing manual workload. However, verifying segmentation results rema...
Authors: Keyi Bian, Marco Caballo, Wenxiu Guo, Haijie Li, Jiao Li, Aidi Liu, Yue Ma, Ioannis Sechopoulos, Yafei Wang, Yaopan Wu, Zhaoxiang Ye, Yuwei Zhang, Yueqiang Zhu, Daan van den Oever
Affiliation: Radboud University Medical Center, Tianjin Medical University Cancer Institute & Hospital, Sun Yat-Sen University Cancer Center
Abstract Preview: Purpose: To develop and validate a nomogram integrating intra- and peritumoral radiomics of contrast-enhanced cone-beam breast CT (CE-CBBCT) and clinicopathologic features for predicting fluorescence ...
Authors: Zhongping Chen, Yuchen Song, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of California, Irvine, University of California Irvine
Abstract Preview: Purpose: Electroacoustic tomography (EAT) monitors the distribution of electrical energy in tissues by detecting acoustics signals induced by electrical pulses during irreversible electroporation (IRE...
Authors: Deng-Yuan Chang, Matthew L. Scarpelli
Affiliation: Purdue University
Abstract Preview: Purpose: Tumor-associated macrophages (TAMs) can be assessed by Ferumoxytol-MRI in breast cancer because they are negatively correlated with the prognosis of patient outcome. However, some studies hav...
Authors: Hisham Assi, Lexi Dowdy, Muhannad N. Fadhel, Michael C. Kolios, Carl Kumaradas, Rasha S Makkia, Tanay N Mannikar
Affiliation: Toronto Metropolitan University, Augusta University, Institute for Biomedical Engineering, Science and Technology (iBEST), Li Ka Shing Knowledge Institute, St. Michaelâs Hospital, Northwestern University, Medical College of Georgia, Augusta University
Abstract Preview: Introduction: Hyperthermia is an emerging strategy for cancer treatment due to its few side effects and low cost. Hyperthermia is used in conjunction with other treatments, such as radiation therapy, ...
Authors: Peymon Ghazi
Affiliation: MALCOVA Inc.
Abstract Preview: Purpose: To develop a near scatterâfree breast CT imaging system that expands coverage of the posterior breast anatomy and enhances contrast resolution for solid masses and microcalcifications, while ...
Authors: Jia Wang, Vani Yadav
Affiliation: Stanford University
Abstract Preview: Purpose: To evaluate the radiation dose and imaging quality of two novel CBCT X-Ray imaging systems used in spine surgeries.
Methods: CBCT scan of ACR CT and CTDI phantoms was performed to acquire ...
Authors: Wenchao Cao, Yingxuan Chen, Haisong Liu, Richard A. Popple, Wenyin Shi, Rodney J. Sullivan, Wentao Wang, Lydia J. Wilson, Zhenghao Xiao
Affiliation: Thomas Jefferson University, The University of Alabama at Birmingham, University of Alabama at Birmingham
Abstract Preview: Purpose: Objectively evaluating brain sparing as a plan-quality indicator for patients receiving stereotactic radiosurgery (SRS) to multiple metastases (multi-met) is complicated by variability in tar...
Authors: Victor B. Kassey, Maciej M. Kmiec, Periannan Kuppusamy, Ryan C. O'Connell, Sergey V. Petryakov, Conner Ubert
Affiliation: Dartmouth College
Abstract Preview: Purpose: High-resolution magnetic field uniformity is essential for quantitative and pre-clinical MRI research. Imaging uniformity is affected by the B0 field, which can be corrected using manual or a...
Authors: David P. Adam, William T. Hrinivich, Taoran Li, Alexander Lu, Michael Salerno, Alejandro Sisniega, Boon-Keng Kevin Teo
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University, University of Pennsylvania
Abstract Preview: Purpose: Cone beam CT (CBCT)-guided online adaptive radiotherapy (ART) is of growing interest, with recent improvements in image quality provided through larger detector panels and fast gantry rotatio...
Authors: Ali Al Asadi, Amanda Lynn DiCarlo, Anthony J. Doemer, Jessie Y. Huang, Ian Y Lee, Alexandra Moceri, Adam Robin, Lisa Scarpace, Mira Shah, Salim Siddiqui, Kundan S Thind
Affiliation: Henry Ford Innovations, Henry Ford Health
Abstract Preview: Purpose: For a patient who had two previous courses of external beam therapy for rectosigmoid adenocarcinoma and presented with painful, recurrent disease in the sacrum, this study describes the first...
Authors: Jonathan Dowell, Wei Luo, Shane McCarthy, Janelle A. Molloy, Markus Murphy
Affiliation: University of Kentucky, Department of Radiation Medicine, Iridesce Solutions, Inc.
Abstract Preview: Purpose: The novel machine quality assurance (QA) device nĂŒFilm (Iridesce Solutions, Lexington KY) allows for an objective assessment of light and radiation fields independent of setup. Herein, the ab...
Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: The Sun Nuclear MapCheck3 device is used for patient-specific QA. While it is typically employed in perpendicular field-by-field delivery using the Isocentric Mounting Fixture, fields not ful...
Authors: Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Gafchromic film is commonly used for quality assurance in SRS/SBRT. However, its application in low-dose measurements, such as monitoring doses on cardiac implantable electronic devicesâwhere...
Authors: Yussuf A. Abdelal, Sebastien A. Gros, Luke Layman, Anil Sethi
Affiliation: Stritch School of Medicine, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago
Abstract Preview: Purpose:
End-to-end (E2E) test is a vital QA check of the overall radiotherapy process from simulation imaging to treatment delivery. Although clinical passing criteria are available, guidelines on...
Authors: Jeonghoon Park, Amritha Praveen, Siddhant Sen, James J. Sohn, Ethan D. Stolen
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation & Cellular Oncology, University of Chicago, Department of Radiation and Cellular Oncology, The University of Chicago, Department of Radiation and Cellular Oncology, University of Chicago, Department of Psychology, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Accurate fabrication of custom boluses is essential in radiation therapy to enhance dose delivery to superficial tumors, especially in anatomically complex regions. This study introduces a no...
Authors: Ana Maria Barragan Montero, Damien Dasnoy, Sylvain Deffet, Valentine Dormal, Colin Gaban, Melanie Ghislaine, Valentin Hamaide, Guillaume Janssens, John A. Lee, Eliot Peeters, Danah Pross, Luciano Rivetti, Benjamin Roberfroid, Romain Schyns, Kevin Souris, Edmond S. Sterpin, Sophie Wuyckens
Affiliation: Ion Beam Applications SA, Hospital Riviera-Chablais, UCLouvain, Multitel, Université Catholique de Louvain, IBA, Faculty of Mathematics and Physics, University of Ljubljana, Universite Catholique de Louvain
Abstract Preview: Purpose: Treatment planning systems (TPSs) are essential for simulating and optimizing radiotherapy treatments. However, clinical TPSs are expensive software commercialized by private companies and of...
Authors: Chih-Wei Chang, Junbo Peng, Richard L.J. Qiu, Justin Roper, Xiangyang Tang, Tonghe Wang, Huiqiao Xie, Xiaofeng Yang, David Yu
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Emory Univ, Emory University, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Limited-angle dual-energy (DE) cone-beam CT (CBCT) is considered a promising solution to achieve fast and low-dose DE imaging on current CBCT scanners without hardware modification. However, ...
Authors: Simona Cacciatore, Albert Du, Ryan T. Flynn, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Julien Smeets, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To evaluate time reduction strategies for the Dynamic Collimation System (DCS) using an IBA (Louvain-la-Neuve, Belgium) proton therapy system. Delivery time for a multi-energy-layer patient s...
Authors: Seungtaek Choi, Laurence Edward Court, Eun Young Han, Yusung Kim, Hunter S. Mehrens, Tucker J. Netherton, Shiqin Su
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Automated treatment planning is gaining traction for its enhanced consistency and efficiency. A key challenge, however, lies in the inability of neural network dose predictions directly trans...
Authors: Xiaohu Li, Jianjun Shen, Guozhi Zhang, Sihua Zhong, Jingjie Zhou
Affiliation: United Imaging Healthcare
Abstract Preview: Purpose:
Visualization of carotid artery vessel wall on computed tomography angiography (CTA) imaging is challenging. This study aims to develop a novel post-processing technique, black-blood compu...
Authors: Yao Chen, Lesley A Jarvis, Allison Matous, Rongxiao Zhang
Affiliation: Dartmouth College, University of Missouri, Dartmouth Cancer Center, Dartmouth Health
Abstract Preview: Purpose: Precise patient positioning is critical in accelerated partial breast irradiation (aPBI) to ensure accurate dose delivery to the tumor bed while minimizing exposure to surrounding healthy tis...
Authors: James M. Balter, Lando S. Bosma, Jorge Tapias Gomez, Nishant Nadkarni, Mert R Sanbuncu, William Paul Segars, Ergys D. Subashi, Neelam Tyagi, Harini Veeraraghavan
Affiliation: University of Michigan, The University of Texas MD Anderson Cancer Center, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Carl E. Ravin Advanced Imaging Laboratories and Center for Virtual Imaging Trials, Duke University Medical Center, Cornell University, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Develop patient-specific virtual digital twin (VDT) cohorts modeling physically realistic spatio-temporal gastrointestinal (GI) organs (stomach and duodenum) digestive motion.
Methods: Pat...
Authors: Hao Chen, Kai Ding, Xiaoyu Hu, Xun Jia, Heng Li, Devin Miles
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Accurately delivering radiation dose is critical in intensity-modulated proton therapy (IMPT), where intrafraction motion management plays a pivotal role. Our proton therapy system equipped x...
Authors: Stephanie Bennett, Ross I. Berbeco, Ning Jin, Sonal Josan, Justin Michael Sheetz, Atchar Sudhyadhom
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Massachusetts - Lowell, Siemens Healthineers, Brigham and Womenâs Hospital and Dana Farber Cancer Institute, Harvard Medical School,, Brigham and Women's Hospital
Abstract Preview: Purpose: AGuIX, a Gadolinium-based theranostic radiosensitizing nanoparticle, is currently under clinical evaluation in Europe and the US. Using patients from the double-blinded NanoBrainMets trial, u...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng Peopleâs Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patientâs inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: Belen Juste, Choonsik Lee, Matthew Mille, Rafael MirĂł, Sergio Morato Rafet, Agustin Santos, Gumersindo VerdĂș
Affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, Universitat PolitĂšcnica de ValĂšncia, Servicio de RadiofĂsica y ProtecciĂłn RadiolĂłgica, Consorcio Hospitalario Provincial de CastellĂłn, National Cancer Institute
Abstract Preview: Purpose: To evaluate the differences in CT scan radiation dose estimation between personalized dose reconstruction, based on real patient CT images, and generalized phantom-based dose calculations.
Authors: Jon Burns, Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma, Timothy Pok Chi Yeung
Affiliation: Reflexion Medical Inc,, RefleXion Medical
Abstract Preview: Purpose: Biology-guided radiotherapy uses positron emissions from FDG-avid tumor volumes to provide a of the planned prescribed dose with high accuracy. The purpose of this work is to characterize BgR...
Authors: Ricardo Garcia Santiago, Narges Miri, Daryl P. Nazareth, Ankit Pant, Mukund Seshadri
Affiliation: Roswell Park Comprehensive Cancer Center
Abstract Preview: Purpose: To develop a transformer-based deep learning network framework for predicting VMAT dose distributions. This can provide fast and efficient calculations with accuracies potentially comparable ...
Authors: Osama R. Mawlawi, Yiran Sun
Affiliation: RICE University, UT MD Anderson Cancer Center
Abstract Preview: Purpose: Conventional PET reconstruction methods often produce noisy images with artifacts due to data/model mismatches and inconsistencies. Recently, deep learning-based conditional denoising diffusi...
Authors: Leslie Harrell, Sanjay Maraboyina, Romy Megahed, Maida Ranjbar, Xenia Ray, Pouya Sabouri
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), University of California San Diego
Abstract Preview: Purpose: Real-time adaptive radiation therapy (ART) dynamically modifies patientsâ treatment plan during delivery to account for anatomical and physiological variations. Addressing ART planning time v...
Authors: Yukio Fujita, Syoma Ide, Kei Ito, Tomohiro Kajikawa, Satoshi Kito, Keiko Murofushi, Yujiro Nakajima, Yuhi Suda, Kentaro Taguchi, Naoki Tohyama, Fumiya Tsurumaki
Affiliation: Komazawa University Graduate School, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Department of Radiology, Kyoto Prefectural University of Medicine
Abstract Preview: Purpose: Stereotactic body radiotherapy (SBRT) for spine metastases is more effective for pain relief and local control than conventional radiotherapy. However, it is associated with vertebral compres...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Maria Jose Medrano, Grant Stevens, Liyan Sun, Justin Ruey Tse, Adam S. Wang, Sen Wang
Affiliation: Department of Radiology, Stanford University, GE HealthCare, Stanford University
Abstract Preview: Purpose: Patient exposure to ionizing radiation is a major concern in CT imaging. Size-specific dose estimation methods can prospectively estimate organ-level radiation doses based on patient sizes an...
Authors: Stephen M Corner, Daiki Hara, Jiasen Ma, Robert W Mutter, Mark D. Pepin, Nicholas B. Remmes, Hok Seum Wan Chan Tseung
Affiliation: Mayo Clinic - Rochester
Abstract Preview: Purpose: Proton minibeam radiotherapy (pMBRT) is a form of spatially fractionated radiation therapy leveraging submillimeter beams to improve the therapeutic ratio. We report on collimator design, com...
Authors: Paul Schwoebel
Affiliation: University of New Mexico Albuquerque
Abstract Preview: N/A...
Authors: Teh Lin, Anna Oneil
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose: Four-dimensional computed tomography(4DCT) is often required to assess organ motions for thoracic and abdominal cancer patients. This study proposes a quality assurance (QA) procedure for two...
Authors: Haiqa Arain, Ping Xia, Zhexuan Zhang
Affiliation: Cleveland Clinic
Abstract Preview: Purpose: To quantify water contents and thickness of wet towel (as a flexible bolus) on curved surface dose for partial breast irradiation.
Methods: Two VMAT partial breast plans (3000 cGy in 5...
Authors: Petr Bruza, Alexander Geiersbach, David J. Gladstone
Affiliation: Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Cherenkov images are two-dimensional projections of the surface light emissions, and lack spatial information about the radiotherapy beam delivery. We implement the first fusion of Cherenkov ...
Authors: D. Michael Lovelock, Charlotte Elizabeth Read, Ren-Dih Sheu, Jing Wang, Tingyu Wang
Affiliation: Icahn School of Medicine at Mount Sinai, Jersey Shore University Medical Center
Abstract Preview: Purpose:
Early Eclipse models use rectangular fluence profiles (widened by the dosimetric leaf gap (DLG) to account for the fact that leaf tips are rounded). Eclipse Version 18 (V18) uses enhanced ...
Authors: Giavanna Luisa Jadick, Patrick J La Riviere, Cailey Riggs
Affiliation: University of Chicago
Abstract Preview: Purpose: We explore the accuracy of physics models for propagation-based x-ray phase-contrast imaging (XPCI) with an eye to future clinical implementation, providing a practical assessment of detectio...
Authors: Guilherme Rosa Ferreira, Dan Giardina, John Karageorgiou, Chris Malone, Allan Thomas
Affiliation: Washington University School of Medicine, Mallinckrodt Institute of Radiology, Washington University School of Medicine
Abstract Preview: Purpose: Radiation segmentectomy has become a primary strategy in 90Y radioembolization, with localized treated volumes that can include up to two liver segments. The goal is complete pathological nec...
Authors: Kristina Bjegovic, Luke Connell, Emil Schueler, Leshan Sun, Lucy Whitmore, Liangzhong Xiang
Affiliation: University of California, Irvine, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: The use of FLASH-RT in the clinic would greatly reduce off-target radiation toxicity in normal tissues. However, due to the hypo-fractionated delivery of prescribed doses at FLASH dose rates,...
Authors: Yao Hao, Yuting Peng, Francisco Javier Reynoso, Tianyu Zhao, Xiandong Zhao
Affiliation: Varian, University of South Florida, Washington University School of Medicine, Washington University School of Medicine, Department of Radiation Oncology
Abstract Preview: Purpose: Ultra-high dose-rate (FLASH) dose rate (> 40 Gy/s) may result in a radio-protective effect in healthy tissue compared with conventional dose rate (CDR). This effect has been observed in vivo ...
Authors: David L. Barbee, David Byun, Ting Chen, Paulina E. Galavis, Siming Lu, Sarah Rosemary Morris, Hesheng Wang, Michael J Zelefsky
Affiliation: NYU Langone Health
Abstract Preview: Purpose: MR-Linac enables dose escalation in prostate SBRT on accurately defined dominant intra-prostate lesion (DIL) on daily MR images. This study aims to evaluate inter-fraction changes in the radi...
Authors: Nrusingh C. Biswal, Manas R. Gartia, Maria Iftesum, Sanjit K. Roy, Gyana Ranjan Sahoo, Elnaz Sheikh, Hem D. Shukla, Madhur Srivastava
Affiliation: Department of Chemistry and Chemical Biology, Cornell University, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Mechanical and Industrial Engineering, Louisiana State University
Abstract Preview: Purpose: Prostate cancer incidence and mortality levels in African-American men are the highest among all ethnic groups. This points to the role of biological factors in driving disparate outcomes. He...
Authors: Hania A. Al-Hallaq, Chih-Wei Chang, Anees H. Dhabaan, Yuan Gao, Shaoyan Pan, Junbo Peng, Richard L.J. Qiu, Keyur Shah, Sibo Tian, Zhen Tian, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Emory University, Whinship Cancer Institute, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Traditional cone-beam computed tomography (CBCT) often requires multiple angular projections, increasing radiation exposure and extending scanning times, which may lead to heightened patient ...
Authors: Mary Feng, Yi Lao, Hui Lin, Hengjie Liu, Xin Miao, Michael Ohliger
Affiliation: University of California, Los Angeles, Department of Radiation Oncology, University of California San Francisco, Department of Radiation Oncology, City of Hope National Medical Center, University of California San Francisco, Siemens Medical Solutions USA Inc.
Abstract Preview: Purpose: 4D MRI with high spatiotemporal resolution is vital to characterize the tumor/tumor motion for liver radiotherapy. However, high-quality 4D MRI requires an impractically long scanning time fo...
Authors: Ruiyan Du, He Huang, Mingzhu Li, Ying Li, Hongyu Lin, Wei Liu, Shihuan Qin, Yiming Ren, Hui Xu, Lian Zhang, Xiao Zhang, Zunhao Zhang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Medical AI Lab, The First Hospital of Hebei Medical University, Hebei Provincial Engineering Research Center for AI-Based Cancer Treatment Decision-Making, The First Hospital of Hebei Medical University, Department of Oncology, The First Hospital of Hebei Medical University
Abstract Preview: Purpose: Monte Carlo (MC) dose calculation is the gold standard in clinical CyberKnife radiation therapy (RT), considering its steep dose gradients and high-freedom non-coplanar beam angles, but extre...
Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...
Authors: Yi Fan, Andrew Friberg, Costas Koumenis, Kevin Teo, Ioannis I Verginadis, Ledi Wang, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: Glioblastomas (GBM) are aggressive and lethal malignancies characterized by their highly refractory nature, contributing to a five-year survival rate of approximately 7%. Physically, GBM exhi...
Authors: Xinxin Deng, Issam M. El Naqa, Jimm Grimm, Lijun Ma, Vitali Moiseenko, Timothy E. Schultheiss, Gopal Subedi, Wolfgang A. Tomé, Ellen D. Yorke, Albert van der Kogel
Affiliation: Montefiore Medical Center, Wellstar Kennestone Hospital Cancer Center, H. Lee Moffitt Cancer Center, Department of Human Oncology, University of WisconsinâMadison, Department of Radiation Oncology, Wellstar Health System, Radiation Oncology, Keck School of Medicine of USC, Georgia Institute of Technology, University of California San Diego, City Of Hope National Medical Centre, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Reirradiation is increasingly utilized in clinical practice but dose-time recovery factors for human subjects remain uncertain. We constructed a reirradiation recovery model for spinal cord e...
Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...
Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu
Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University
Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinsonâs disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...
Authors: David P. Adam, Allison Cartee, Eric C. Frey, Michael Ghaly, Bin He, Robert Francois Hobbs, Natalie Rose Kania, Ana Kiess, Ian Marsh, Bonnie N. C. President, Steven Rowe, George Sgouros, Phuoc Tran, Hao Wang
Affiliation: Johns Hopkins University, Radiopharmaceutical Imaging and Dosimetry, LLC (Rapid), 2The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins Medical Institute, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Oncology, Johns Hopkins University, School of Medicine, Department of Radiology, University of North Carolina, Chapel Hill
Abstract Preview: Purpose: Advanced treatment paradigms combining SPECT/CT imageable, alpha emitting, radiopharmaceutical therapy (RPT) and stereotactic body radiotherapy (SBRT) can provide the potential of dose escala...
Authors: Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Edward L. Clouser, Yi Rong, Jun Tan, Jennifer Yan, Xiang Sheng Yan
Affiliation: Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
To identify planning techniques that consistently result in robust VMAT-TBI plans that allow for larger patient setup errors.
Methods:
Conventional planning method often results in p...
Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang
Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...
Authors: Lando S. Bosma, Victoria Brennan, Nicolas Cote, ChengCheng Gui, Nima Hassan Rezaeian, Jue Jiang, Sudharsan Madhavan, Josiah Simeth, Neelam Tyagi, Harini Veeraraghavan, Michael J Zelefsky
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, NYU Langone Health, University Medical Center Utrecht, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Deep learning-based deformable image registration (DIR) models often lack robustness when applied to datasets with differing imaging characteristics. We aimed to (1) improve registration netw...
Authors: Leon Dunn
Affiliation: IsoAnalytics Pty. Ltd.
Abstract Preview: Purpose: The purpose of this work is to present the development and results of an automated Varian Trajectory Log file processing software platform called Sentinel (IsoAnalytics Pty. Ltd.).
Methods...
Authors: Hengjie Liu, Dan Ruan, Ke Sheng, DI Xu
Affiliation: Physics and Biology in Medicine, University of California, Los Angeles, Department of Radiation Oncology, University of California, San Francisco, Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose:
State-of-the-art deep learning-based deformable image registration often uses large, complex models directly adapted from computer vision tasks but achieves only comparable performance to ...
Authors: Avneesh Chhabra, Zhiyue J. Wang, Qing Yuan
Affiliation: University of Texas Southwestern Medical Center
Abstract Preview: Purpose: Magnetic susceptibility artifacts from dental arches and hardware often compromise MRI neurography of jaw and facial nerves. This study aims to characterize these artifacts and provide insigh...
Authors: Liyuan Chen, Sepeadeh Radpour, David Sher, Jing Wang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center
Abstract Preview: Purpose: Accurate lymph node malignancy prediction is pivotal in optimizing radiation treatment strategies for head and neck (HN) cancer patients. While conventional radiomics models leverage intensit...
Authors: Austen N. Curcuru, Winter Green, Yao Hao, Jiayi Liu, Yuting Peng, Tiezhi Zhang, Xiandong Zhao
Affiliation: Washington University School of Medicine, Department of Radiation Oncology, WashU Medicine, Virginia Commonwealth University, Washington University School of Medicine, Washington University in St. Louis
Abstract Preview: Purpose: We proposed a treatment planning optimization method that utilizes customized spot map modification to achieve less dosimetry uncertainty, monitor unit ratio (MUR) and neutron dose in a spot ...
Authors: Manuel M. Arreola, Hugh Davis, Daniella Fabri, Emily L. Marshall, BC Schwarz
Affiliation: University of Florida
Abstract Preview: Purpose:
This study aims to map procedure names, descriptions, and CPT codes from a Hybrid Angio-CT room to the American College of Radiology (ACR) Common Lexicon. This mapping will support expedit...
Authors: Asma Amjad, Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate and precise linac-based SRS commissioning can be very challenging. Thus, it is important to increase the confidence in the measurement at each step prior to end-to-end testing. The p...
Authors: Eric C. Ford, Yulun He, Minsun Kim, Dustin Melancon, Juergen Meyer, Dong Joo Rhee, Yinghua Tao
Affiliation: Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, MD Anderson Cancer Center, University of Washington
Abstract Preview: Purpose: To develop and evaluate an automated-planning technique capable of generating high-quality treatment plans for hippocampal-sparing-whole-brain radiation therapy.
Methods: An auto-planning ...
Authors: Samuel Kadoury, Redha Touati
Affiliation: Polytechnique Montréal
Abstract Preview: Purpose:
Generating synthetic CT images from MR acquisitions for radiotherapy planning allows to integrate soft tissue contrast alongside density information stemming from CT, thus improving tumor ...
Authors: Ted Lynch
Affiliation: Sun Nuclear, a Mirion Medical Company
Abstract Preview: Purpose: A novel ultrasound quality assurance method is presented that constructs âsynthetic spheresâ at arbitrary locations within the image frame by combining correlation length measurements from a ...
Authors: Jennifer Kwak, Chelsea Manica, Justin K. Mikell, Michael Silosky, Wendy Siman
Affiliation: Washington University School of Medicine in St. Louis, University of Colorado Anschutz Medical Campus, School of Medicine, Rocky Vista University
Abstract Preview: Purpose:
This study evaluates synthetic planar imaging (synP) from SPECT projections against conventional planar imaging, focusing on detectability, spatial resolution, and feasibility. SynP allows...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The Ohio State University James Cancer Hospital, The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: As accessibility is becoming a topic of increasing importance, we can consider how to make medical physics more accessible to those with various disabilities, including those with visual impa...
Authors: Azza Mohamed Ahmed, Nadine Francis, Osama Khan, Nabil Maalej, Aamir Raja, Briya Tariq
Affiliation: Khalifa University
Abstract Preview: Purpose: The study aims to evaluate the task-specific diagnostic performance of spectral photon-counting CT (SPCCT) using application-specific phantoms.
Methods:
Parameters such as linearity res...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...
Authors: Wen C. Hsi, Tae Kyu Lee, Biniam Yo Tesfamicael
Affiliation: Allina Health, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Oklahoma Proton Center
Abstract Preview: Purpose: When minimal dose-variations induced by inter-fractional anatomical-changes and positioning-deviation were found for having limited impact on clinic-outcomes of oropharyngeal head-and-neck (H...
Authors: Xiangli Cui, Wanli Huo, Jie Li, Lingling Liu, Tao Ma, Yuanyuan Wang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Ion Medical Center, Hefei Cancer Hospital, Chinese Academy of Sciences, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University
Abstract Preview: Purpose: In practice, treatment planning systems (TPS) of proton therapy require a CT calibration curve, which relates Hounsfield units (HU) to relative stopping power (RSP). Single-energy CT as a sta...
Authors: Annie Cooney, Kenneth L. Homann, Somayeh Taghizadehghahremanloo, Adam D. Yock, Hong Zhang
Affiliation: Assistant Professor, Vanderbilt University Medical Center
Abstract Preview: Purpose:
Digital radiotherapy data has been standardized using the DICOM format. However, different radiotherapy software environments interpret identical data differently due to inherent software ...
Authors: Lei Fu, Eric Gressen, Yingcui Jia, Shari Rudoler, Yevgeniy Vinogradskiy, Qianyi Xu
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: InTempo imaging in the Accuray CyberKnife System improves the ability to track/correct target motion during treatment. However, no studies have provided information on the impact of InTempo I...
Authors: Shusen Jing, Qihui Lyu, Dan Ruan, Ke Sheng, Qifan Xu
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose: Conventional computed tomography (CT) measures the collective attenuation of primary photon fluence and then reconstructs the 3D images without using the timing information of individual phot...
Authors: Kevin Peter Risolo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: To quantify the improved efficiency of checking patient treatment plan MU by utilizing RadFormationâs ClearCalc script-based program.
Methods: A total of 58 patients planned for treatment ...
Authors: Alejandro Bertolet, Jorge Naoki Dominguez Kondo, Bruce A. Faddegon, Kathryn D Held, Nicolas Henthorn, Jay LaVerne, Thongchai Masilela, Stephen J. McMahon, Isaac Meyer, Victor V. Onecha, Harald Paganetti, Jose A. Ramos-Mendez, Jan PO Schuemann, Wook-Geun Shin, Michael Taylor, John Warmenhoven
Affiliation: Massachusetts General Hospital, Queen's University Belfast, Massachusetts General Hospital and Harvard Medical School, University of California San Francisco, University of Manchester, Notre Dame University
Abstract Preview: Purpose: TOPAS-nBio brings a cutting-edge Monte Carlo (MC) simulation framework to the research community to test hypotheses of radiation effects at the nanometer/cell scale. Here, we present the deve...
Authors: Petr Bruza, Rafael Carballeira, Megan Clark, David J. Gladstone, Austin Sloop, Roman Vasyltsiv, Kevin Jacob Willy
Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Develop an optical dosimetry system to accomplish standard of care on-patient dosimetry and pretreatment quality assurance for ultra-high dose rate (UHDR) electron therapy ahead of human tria...
Authors: Freeman Jin, Paul J. Keall, Alistair MacDonald, Adam Mylonas, Chandrima Sengupta
Affiliation: Image X Institute, Faculty of Medicine and Health, University of Sydney, Image X Institute, Faculty of Medicine and Health, The University of Sydney, Image X Institute, School of Health Sciences, University of Sydney
Abstract Preview: Purpose: During radiation therapy, tumours in the prostate may move from the planned treatment position, leading to significant dose deviations above clinical tolerances Surveys have indicated the nee...
Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang
Affiliation: RefleXion Medical
Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...
Authors: Quyen Duong, Si Young Jang, Soyoung Lee, Samuel Ming Ho Luk
Affiliation: Boston University, Department of Radiation Oncology, University of Vermont Medical Center, Boston Medical Center
Abstract Preview: Purpose: To investigate the clinical impact of physical MLC gaps changes with Millennium 120 MLC on Enhanced Leaf Modeling (ELM) and patient plans, and to establish a new MLC model in Eclipse v18.0 on...
Authors: Yujie Chi, Yao Hao, Xun Jia, Youfang Lai, Yuting Peng, Francisco Javier Reynoso, Lingshu Yin, Tianyu Zhao, Xiandong Zhao
Affiliation: Johns Hopkins University, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Physics, University of Texas at Arlington, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, University of South Florida
Abstract Preview: Purpose: FLASH radiation therapy has shown remarkable tissue sparing effects compared to radiation therapy at conventional dose rates (CDR). Yet, its mechanism remains unclear. Radical production modu...
Authors: Siyong Kim, Ava Paek, Joseph B. Schulz, James J. Sohn, Eric D. Stolen, Ethan D. Stolen
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Central Florida, Virginia Commonwealth University, Department of Radiation and Cellular Oncology, University of Chicago, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose: The American Association of Physicists in Medicine Task Group 142 (AAPM TG-142) guidelines recommend three measurements during monthly quality assurance to keep results within two standard de...
Authors: Zhaohui Han, Piotr Zygmanski
Affiliation: Brigham and Womenâs Hospital, Dana Farber Cancer Institute, Harvard Medical School, Department of Radiation Oncology, Brigham and Womenâs Hospital, Dana-Farber Cancer Institute, Harvard Medical School
Abstract Preview: Purpose: Real-time motion tracking/gating are oftentimes limited to a single sagittal plane on many magnetic resonance linear accelerators (MR-Linac). Out-of-plane motion is therefore difficult to det...
Authors: Stephen R. Bowen, Shijun Chen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Qianqian Tong, Jiajie Wang, Shouyi Wang, Faisal Yaseen
Affiliation: The University of Texas at Austin, Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington
Abstract Preview: Purpose: Tumor subregion clustering and prediction of region-specific response can augment assessments and adaptive treatment decisions. A modeling framework was constructed to predict chemoradiation ...
Authors: Guangjun Li, Ying Song, Huanan Tang, Tianxiong Wu, Qiuyi Ye, Wei Zhang
Affiliation: West China Second Hospital of Sichuan University, United Imaging Healthcare, West China Hospital of Sichuan University
Abstract Preview: Purpose:
To propose a general low-dose reconstruction model for ultra-sparse-view cone-beam CT (CBCT) and evaluate its clinical application in improving image quality and reducing radiation dose fo...
Authors: Fred B. Bateman, Ilaria M. Luna, Ronald E. Tosh
Affiliation: Sidwell Friends School, NIST, Dosimetry Group, Radiation Physics Division, National Institute of Standards and Technology
Abstract Preview: Purpose: To exploit the rapid response time and dose sensitivity of ultrasonic detection methods for resolving pulse structure in FLASH-level beams.
Methods: Two ultrasonic transducers position...
Authors: Laura I. Cervino, Wendy B. Harris, Paulo Quintero, Hao Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To evaluate the impact of the prediction uncertainty from CBCT-based synthetic CT (sCT) generation in abdominal adaptive radiotherapy.
Methods: CT and CBCT images from 65 abdominal pat...
Authors: Yunxiang Li, Weiguo Lu, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Curating high-quality, labeled data for medical image segmentation can be challenging and costly, considering the existence of various image domains with differing modalities/protocols. Cr...
Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine
Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...
Authors: Eric S. Diffenderfer, Lei Dong, Alejandro Garcia, Wenbo Gu, Michele M. Kim, Alexander Lin, Kai Mei, Peter B. Noël, Boon-Keng Kevin Teo, Lingshu Yin, Jennifer Wei Zou
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania
Abstract Preview: Purpose: We present a novel 3D-printed range-modulating devices with spatially modulated density for FLASH particle therapy. By varying density distributions, spread-out Bragg peaks(SOBPs) can be gene...
Authors: Joseph A. Miccio, Nicholas J. Potter, Zain Siddiqui
Affiliation: Penn State Health Milton S. Hershey Medical Center
Abstract Preview: Purpose: Fiducial markers are the gold standard for prostate alignment during CT-based image-guided radiotherapy (IGRT). Radiopaque hydrogel rectal spacers reduce rectal toxicity by displacing the rec...
Authors: Avinash Mudireddy, Nathan Shaffer, Joel J. St-Aubin
Affiliation: University of Iowa
Abstract Preview: Purpose: This work demonstrates preliminary results in training a reinforcement learning (RL) network to perform VMAT machine parameter optimization.
Methods: We implemented a policy gradient RL al...
Authors: Brook Byrd, Lisha Chen, Michael LaRiviere, Baozhu Lu, John Plastaras, Brian W Pogue, Emily Xiong, Timothy C. Zhu, Yifeng Zhu
Affiliation: Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, University of Wisconsin - Madison
Abstract Preview: Purpose: For total skin electron therapy (TSET), achieving optimal dose distribution depends on precise patient positioning, which is often influenced by daily variability. Cherenkov imaging offers a ...
Authors: Dong Wook Kim, Hojae Kim, Hojin Kim, Jin Sung Kim, Tae Ho Kim, Sangmin Lee
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: The CyberKnife system, designed for stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT), considers SRS MapCHECK an effective tool for patient-specific QA (PSQA). This wo...
Authors: Jean-Pierre Bissonnette, Catherine Coolens, Laura Dawson, Ryan A Kuhn, Michael Maddalena, Teo Stanescu
Affiliation: Princess Margaret Hospital, The Princess Margaret Cancer Centre - UHN, University of Toronto, Princess Margaret Cancer Centre
Abstract Preview: Purpose: To investigate the generation and reproducibility of 3D hypoxia maps in liver hepatocellular carcinoma (HCC) patients using data derived from an Intravoxel Incoherent Motion (IVIM) MR sequenc...
Authors: Cambridge L Bui-Nguyen, Alexander S. Nguyen, Liqiang (Lee) Tao
Affiliation: Varian AOS @Epic Care, UC Berkeley
Abstract Preview: Purpose: To quantity variations in Winston Lutz (WL) test results due to different energies used in SBRT, SRT or SRS.
Methods: A WL phantom with a 6.4 mm diameter center radio-opaque sphere is used...
Authors: Harold Y Hu, Yanle Hu, Shuai Leng, Maryam Sadeghian, Joe Swicklik
Affiliation: Mayo Clinic Arizona, Basis Scottsdale, Mayo Clinic
Abstract Preview: Purpose: Radiotherapy CT simulation often requires two scans: a non-contrast scan for dose calculation and a contrast-enhanced scan for target delineation. Photon-counting-detector (PCD) CT allows the...
Authors: Go Akamatsu, Hiroaki Ikawa, Yuma Iwao, Han Gyu Kang, Masashi Koto, Hideyuki Mizuno, Akram Mohammadi, Makoto Shinoto, Minoru Tajiri, Hideaki Tashima, Chie Toramatsu, Taiga Yamaya
Affiliation: National Institutes for Quantum Science and Technology
Abstract Preview: Purpose: In-beam positron emission tomography (PET), in which positron emitters produced through fragmentation reactions are visualized, is a practical method for range verification in particle therap...
Authors: Laura I. Cervino, Linda X. Hong, Jessica Pagan, Angelica A. Perez-Andujar, Maria Thor
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Memorial Sloan-Kettering Cancer Center
Abstract Preview: Purpose: Three-dimensional conformal radiotherapy (3DCRT) and Volumetric-Modulated Arc Therapy (VMAT) are used to treat locally advanced breast cancer. The 3DCRT treatment plans use the treatment fiel...
Authors: Michael Baine, Yang Lei, Yu Lei, Ruirui Liu, Tian Liu, Jing Wang
Affiliation: Icahn School of Medicine at Mount Sinai, University of Nebraska Medical Center
Abstract Preview: Purpose: Accurate 3D deformable registration of MRI and ultrasound (US) is essential for real-time image guidance during high-dose-rate (HDR) prostate brachytherapy. However, MRI-US registration of th...
Authors: Caiden Atienza, Daniel E. Hyer, Samuel D. Rusu, Blake R. Smith, Joel J. St-Aubin
Affiliation: Iowa Health Care, University of Iowa
Abstract Preview: Purpose: Pinnacle3 TPS (Philips Radiation Oncology Systems, Fitchburg, WI, USA) support is set to end by December 31, 2026. This work presents a validated method to archive Pinnacle data, which may be...
Authors: Steve B. Jiang, Ruiqi Li, Hua-Chieh Shao, Kenneth Westover, You Zhang, Tingliang Zhuang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose:
Respiratory motion is a long-standing challenge for lung SBRT, particularly for centrally-located lung tumors where increased toxicity demands more precise motion management during treatme...