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Results for "artificial intelligence": 96 found

3D Topological Features for Outcome Assessment of Therapeutic Responses to Neoadjuvant Chemoradiotherapy (NCRT) with and without Anti-CD40 Immunotherapy in Local Advanced Rectal Cancer (LARC)

Authors: Todd A Aguilera, Gaurav Khatri, Jiaqi Liu, Hao Peng, Nina N. Sanford, Robert Timmerman, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT southwestern medical center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study first integrates 3D topological data analysis with radiomics from local advanced rectal cancer T2-weighted MRI to evaluate therapeutic responses and quantify treatment-induced c...

A Combination of Radiomics and Dosiomics for Gross Tumor Volume Regression in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR)

Authors: Hao Peng, Yajun Yu

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel ablative radiation dosing scheme developed by our institution. This study aims to establish a regression...

A Conditional Point Cloud Diffusion Model for Deformable Liver Motion Tracking Via a Single Arbitrarily-Angled X-Ray Projection (PCD-Liver)

Authors: Yunxiang Li, Hua-Chieh Shao, Chenyang Shen, Jing Wang, Jiacheng Xie, Shunyu Yan, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Accurate liver deformable motion tracking is essential in image-guided radiotherapy to enable precise tumor targeting during treatment. We developed a conditional point cloud diffusion model ...

A Deep Learning-Based Approach for Rapid Prediction of IMRT/VMAT Patient-Specific Quality Assurance for Online Adaptive Plans Generated with a 0.35T MR-Linac

Authors: Suman Gautam, Tianjun Ma, William Song

Affiliation: Virginia Commonwealth University

Abstract Preview: Purpose: We propose an artificial intelligence (AI)-based method to rapidly predict the patient-speciïŹc quality assurance (PSQA) results for magnetic resonance (MR)-guided online adaptive radiation th...

A Diffusion-Based AI Framework for Continuous Deformable Image Registration and Time-Resolved Dynamic CT Generation

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Gregory Szalkowski, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Respiratory motion management is crucial for accurate radiation delivery to moving targets while protecting healthy tissue, relying on time-resolved volumetric imaging and continuous deformab...

A Dynamic Reconstruction and Motion Estimation Framework for Cardiorespiratory Motion-Resolved Real-Time Volumetric MR Imaging (DREME-MR)

Authors: Jie Deng, Xiaoxue Qian, Hua-Chieh Shao, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Based on a 3D pre-treatment MRI scan, we developed DREME-MR to jointly reconstruct the reference patient anatomy and a data-driven, patient-specific cardiorespiratory motion model. Via a moti...

A Foundational Model for Medical Imaging Modality Translation in Head and Neck Radiotherapy

Authors: Jie Deng, Yunxiang Li, Xiao Liang, Weiguo Lu, Jiacheng Xie, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Recently, foundational models trained on large datasets have shown remarkable performance across various tasks. Developing a foundational model for medical image modality translation in head-...

A Ground Truth Label-Mediated Method for Improved Bone and Gas Cavity Definition for MRI-Guided Online Adaptive Radiotherapy Workflows Using Synthetic CT Images.

Authors: Benito De Celis Alonso, Braian Adair Maldonado Luna, Gerardo Uriel Perez Rojas, René Eduardo Rodríguez-Pérez, Kamal Singhrao

Affiliation: Department of Radiation Oncology, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, Faculty of Physics and Mathematics, Benemérita Universidad Autónoma de Puebla

Abstract Preview: Purpose: Artificial Intelligence (AI)-generated synthetic CT (sCT) images can be used to provide electron densities for dose calculation for online adaptive MRI-guided stereotactic body radiotherapy (...

A Hybrid Population-Based and Patient-Specific Framework for 2D–3D Deformable Registration-Driven Limited-Angle Cone-Beam CT Estimation

Authors: Xiaoxue Qian, Hua-Chieh Shao, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Limited-angle CBCT (LA-CBCT) reduces imaging time and dose but suffers from under-sampling artifacts. 2D–3D deformable registration addresses this problem by estimating LA-CBCTs from defor...

A Monte Carlo-Based Secondary Dose Verification Tool for Treatment Plans of Robotic Radiosurgery System

Authors: Chuxiong Ding, Xuejun Gu, Heejung Kim, Weiguo Lu, Yang Kyun Park, Yulong Yan

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: The purpose of this study was to develop and evaluate a Monte Carlo (MC) dose calculation software (DosemanCK) for secondary dose verification of CyberKnife (CK) treatment plans. Unlike tradi...

A Motion Tracking Quality Assurance Platform for the Leksell Gamma Knife Hdmm System

Authors: Tsuicheng D. Chiu, Strahinja Stojadinovic, Aaron Thomlinson, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: Design and develop an automated verification and validation platform for the Elekta Leksell Gamma Knife (GK) Icon/Esprit High-Definition Motion Management (HDMM) system.

Methods: The H...

A Novel Margin-Based Focal Distance Loss for Lesion Segmentation in Medical Imaging

Authors: Weiguo Lu, Hua-Chieh Shao, Guoping Xu, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Neural network-based lesion segmentation remains a significant challenge due to the low contrast between lesions and surrounding tissues (high ambiguity) and the variability of lesion shap...

A SAM-Guided and Match-Based Semi-Supervised Segmentation Framework for Medical Imaging

Authors: Weiguo Lu, Jax Luo, Xiaoxue Qian, Hua-Chieh Shao, Guoping Xu, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Harvard Medical School

Abstract Preview: Purpose:
Semi-supervised segmentation leverages sparse annotation information to learn rich representations from combined labeled and label-less data for segmentation tasks. This study leverages th...

A Tumor Tracking Method in Surface-Guided Radiotherapy

Authors: Penghao Gao, Zejun Jiang

Affiliation: Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: Real-time tumor tracking can effectively compensate for the impact of respiratory motion on dose distribution. We propose a patient-specific external-internal correlation model driven by opti...

AI-Assisted Algorithm to Generate Patient Postures for Tset Dose Evaluation

Authors: Kostas Danniidis, Agelos Kratimenos, Yufu Wang, Timothy C. Zhu, Yifeng Zhu

Affiliation: University of Pennsylvania

Abstract Preview: Purpose: This study aims to develop software and algorithms utilizing artificial intelligence (AI) to seamlessly create 3D patient postures during Total Skin Electron Therapy (TSET). The resulting mes...

AI-Driven Early Detection of Digital Radiography Performance Degradation: A Predictive Quality Control Approach

Authors: Giovanni Iacca, Gloria Miori, Laura Orsingher, Daniele Ravanelli, Annalisa Trianni

Affiliation: Department of Information Engineering and Computer Science, University of Trento, Medical Physics Department, S.Chiara Hospital, APSS

Abstract Preview: Purpose: This study aims to leverage artificial intelligence (AI) to predict and identify performance degradation in Digital Radiography (DR) systems, enabling proactive maintenance and minimizing cli...

Accelerated Proton Density Imaging Via T2-Guided Cyclegan Super-Resolution without Paired Low-Resolution and High-Resolution Data

Authors: Yunxiang Li, Xinlong Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Acquiring high-resolution (HR) proton density (PD) images is time-consuming, while lower-resolution (LR) PD scans are faster but can lack sufficient details. We propose CycleHR, a T2-contrast...

Advancing Biodosimetry with AI: Detecting Dicentric Chromosomes Using Convolutional Neural Networks

Authors: Adayabalam Balajee, Elijah Berberette, Maria Escalona, Dray Gentry, Chester R. Ramsey, Terri Ryan

Affiliation: ORAU, Thompson Proton Center, University of Tennessee

Abstract Preview: Purpose:
Dicentric chromosomes, characterized by two centromeres on a single chromosome, are key biomarkers in biological dosimetry for quantifying ionizing radiation exposure. However, manual dete...

Advocating for Survival Prediction Models in Risk Stratification for Cancer Treatment Outcomes

Authors: Meixu Chen, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Cancer treatment outcome prediction plays a pivotal role in guiding therapeutic decisions and optimizing patient care. Traditionally, binary prediction models have been widely used for risk s...

An Automated Notification System for Identifying Patients Eligible for Biology-Guided Radiotherapy

Authors: Shahed Badiyan, Bin Cai, Tu Dan, Michael Dohopolski, Steve B. Jiang, Deepkumar Mistry, Arnold Pompos, Robert Timmerman, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Biology-guided radiotherapy (BGRT) offers significant potential for personalized and adaptive cancer treatment, with clinically available systems such as SCINTIX from Reflexion now being intr...

Analysis of Collimation during Fluoroscopically-Guided Interventions: Using a Large-Scale Archive to Assess Collimation during Different Procedures

Authors: James R Duncan, Nikhat Fatima Mansoori, Allan Thomas

Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine

Abstract Preview: Purpose: Collimation during fluoroscopically-guided interventions (FGIs) can not only reduce radiation exposure to patients and personnel but also improve image quality. Nonetheless, there are concern...

Artificial Intelligence (AI)-Driven Automatic Contour Quality Assurance (QA) with Uncertainty Quantification

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Accurate delineation of treatment targets and organs-at-risk is crucial for radiotherapy. Despite significant progress in artificial intelligence (AI)-based automatic segmentation tools, effi...

Artificial Intelligence Based Auto-Contouring for Organs at Risk in Head and Neck

Authors: Mylinh Dang, Laila A Gharzai, Xinlei Mi, Poonam Yadav

Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine

Abstract Preview: Purpose: Delineation of organs at risk (OAR) in the head/neck region requires substantial physician time. Many artificial intelligence (AI) based auto-contouring software are commercially available. T...

Artificial Intelligence-Powered Conventional Energy Integrating Detector-Based Coronary CT Angiography: Learning High-Resolution and Multi-Energy Imaging from Photon-Counting Detector CT

Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson

Affiliation: Mayo Clinic

Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...

Assessment of Automated Planning Templates for Genitourinary and Gastrointestinal Disease Sites for Online MR-Guided Adaptive Radiotherapy

Authors: Shahed Badiyan, Tsuicheng D. Chiu, Viktor M. Iakovenko, Steve Jiang, Christopher Kabat, Mu-Han Lin, Roberto Pellegrini, Arnold Pompos, Edoardo Salmeri, David Sher, Sruthi Sivabhaskar, Justin D. Visak

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Global Clinical Science, Elekta AB, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Adaptive treatment planning requires robust strategies to enable streamlined on-couch processes, creating a significant barrier for planners transitioning from conventional to adaptive planni...

Auto-Contouring of OAR Enhances Patient Safety and Workflow in Gamma Knife Stereotactic Radiosurgery

Authors: Sven Ferguson, S. Murty Goddu, Ana Heermann, Taeho Kim, Nels C. Knutson, Hugh HC Lee, Shanti Marasini, Timothy Mitchell, Seungjong Oh, Kevin Renick

Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis

Abstract Preview: Purpose: In the Gamma Knife stereotactic radiosurgery (GK-SRS), the delineation of organs-at-risks (OARs) was not fully automated. Due to the cumbersome nature of manual OAR contouring, dose evaluatio...

BEST IN PHYSICS MULTI-DISCIPLINARY: Motion-Resolved Dynamic CBCT Reconstruction Using Prior-Model-Free Spatiotemporal Gaussian Representation (PMF-STGR)

Authors: Hua-Chieh Shao, Chenyang Shen, Jiacheng Xie, Shunyu Yan, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Motion-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection), is highly desired for regular/irregular motion chara...

CT-Free PET Imaging: Synthetic CT Generation for Efficient and Accurate PET-Based Planning

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
PET is used in radiotherapy workflows for accurate target delineation. However, a separate CT scan is typically required for attenuation correction in PET imaging and for registering PET-d...

Can AI Agent be a Good Judge for Online Adaptive Radiotherapy Plan Evaluation?

Authors: Steve B. Jiang, Mu-Han Lin, Dan Nguyen, Beiqian Qi, Daniel Yang, Ying Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Online adaptive radiotherapy (oART) is a resource-intensive workflow requiring significant time and effort required from clinicians, particularly for the online evaluation of plan quality....

Chat with Oncology Information System Via Large Language Model

Authors: Michael Dohopolski, Xuejun Gu, Hao Jiang, Steve B. Jiang, Christopher Kabat, Jingying Lin, Weiguo Lu, Michael Tang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Neuralrad LLC, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: To streamline access to clinical data stored in Oncology Information Systems such as MOSAIQ or ARIA, we developed an AI-powered chatbot capable of querying, summarizing, and interactively ans...

Compressed Sensing Enhanced Radiomic Feature Selection for Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR)

Authors: Hao Peng, Yajun Yu

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a new treatment paradigm pioneered by our institution. But the early decision-making process in PULSAR is challe...

Continuous Professional Development for Medical Physicists on AI Principles from the User's Perspective.

Authors: Mauro Carrara, Olivera Ciraj Bjelac, John E. Damilakis, Andre L. Dekker, Serafina Di Gioia, Renato Padovani, Egor Titovich, Qingrong Jackie Wu

Affiliation: University of Crete, Duke University Medical Center, Maastro Clinic, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, International Centre for Theoretical Physics

Abstract Preview: Purpose: The purpose of this work is to present the International Atomic Energy Agency (IAEA) activity in providing medical physicists (MPs) with knowledge, skills, and competencies to support the saf...

Deep Learning-Based Ventricular Auto-Segmentation for Dosimetric Analysis in Intraventricular Tumor SRS

Authors: John Byun, Juan J Cardona, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Yusuke Hori, Hao Jiang, Fred Lam, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford School of Medicine, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Intraventricular tumors pose significant challenges in neurosurgery due to their complex location. Therefore, brain SRS could be a better treatment option. At our institution, some patient...

Deeptuning: A Deep Learning Dose Prediction Framework for Interactive Plan Tuning

Authors: Mingli Chen, Huan Amanda Liu, Weiguo Lu, Lin Ma

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Mayo Clinic

Abstract Preview: Purpose: To reduce the back-and-forth in planning process between physicians and dosimetrists resulting from trade-off exploration, we proposed a novel deep learning framework called DeepTuning.
Me...

Developing an AI-Driven Predictor for Forecasting Treatment Outcomes in Patients with Early-Stage Breast Cancer

Authors: Lucy Jiang, Chengyu Shi

Affiliation: Department of Radiation Oncology, City of Hope Orange County, Amity Regional High School (10th Grade)

Abstract Preview: Purpose: Early-stage breast cancer is common among females, with typically high local tumor control rates (LCR). Brachytherapy is a common way to achieve LCR following surgery. However, the patients m...

Development and Validation of a Deep Learning-Based Auto-Segmentation Module for Vestibular Schwannoma

Authors: John Byun, Steven D Chang, Cynthia Fu-Yu Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Xianghua Ye, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Neurosurgery, Stanford University, Department of Radiation Oncology, Stanford University, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate and automated delineation of vestibular schwannoma (VS) volume is crucial for disease management, as both treatment approaches (stereotactic radiosurgery and invasive surgery) and mo...

Development and Validation of an MR-Compatible Anthropomorphic Motion Phantom for Liver Motion Assessment and MR-Linac Gating System Optimization

Authors: Tsuicheng D. Chiu, Weiguo Lu, Aaron Thomlinson, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose: To develop and validate an MR-compatible anthropomorphic motion phantom to assess liver motion, real-time dosimetry, and gating system performance under controlled and reproducible respirator...

Development of a Radiomics-Dosiomics Mcode Ontology Extension for Radiotherapy

Authors: John Kildea, Odette Rios-Ibacache, Amal Zouaq

Affiliation: McGill University, Polytechnique Montréal

Abstract Preview: Purpose:
Even though Electronic medical records (EHRs) are now in widespread use in healthcare, and Artificial Intelligence tools incorporating radiomics are used to identify tumors in medical imag...

Development of an Orthogonal X-Ray Projections-Guided Cascading Volumetric Reconstruction and Tumor-Tracking Model for Adaptive Radiotherapy

Authors: Penghao Gao, Zejun Jiang, Huazhong Shu, Linlin Wang, Gongsen Zhang, Jian Zhu

Affiliation: Laboratory of Image Science and Technology, Key Laboratory of Computer Network and Information Integration, Southeast University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Artificial Intelligence Laboratory, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences

Abstract Preview: Purpose: We propose a cascading framework for time-varying anatomical volumetric reconstruction and tumor-tracking, guided by onboard orthogonal-view X-ray projections.
Methods: We employe multiple...

Empowered By Artificial Intelligence and Knowledge Map in Bio-Medical Physics Course

Authors: Jia Jing, Hui Lin, Daming Meng, Zhenyu Xiong

Affiliation: School of Physics, Hefei University of Technology, Rutgers Cancer Institute of New Jersey

Abstract Preview: Purpose: Artificial intelligence (AI) is attempting to understand the essence of intelligence and produce a new type of intelligent machine that can respond in a way similar to human intelligence. AI ...

Enhanced Prognostic Modeling for Clear Cell Renal Cell Carcinoma Via Multi-Omics Model and Computational Pathology Foundation Model Integration

Authors: James Brugarolas, Meixu Chen, Raquibul Hannan, Payal Kapur, Jing Wang, Kai Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Accurate prognosis of clear cell renal cell carcinoma (ccRCC) is essential for guiding personalized treatment planning. In this study, we present a multi-modal ensemble model (MMEM) that inte...

Evaluation of Treatment Planning Feasibility and Dosimetric Quality of the Reflexionℱ X1 System for Complex Spinal Targets

Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center

Abstract Preview: Purpose:
The RefleXionÂź X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...

Expert Verification of AI-Generated Cardiac Substructures and Dosimetric Differences between Auto-Contoured and Manually Delineated Contours

Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding

Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington

Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...

Feasibility Study of Ethos Artificial-Intelligence Online Adaptive Prostate SBRT

Authors: Miguel Albaladejo, Ana Corbalan, Aitor Ortega, Vicente Puchades, David Ramos, Alfredo Serna-Berna, Jonattan Suarez

Affiliation: Hospital General Universitario Santa Lucia

Abstract Preview: Purpose:
Prostate SBRT treatments are frequently delivered using standard VMAT IGRT technique. The aim of this study is to test the feasibility of Ethos Artificial Intelligence (AI) prostate SBRT b...

Feasibility of Using a Convolutional Neural Network to Predict Physician Evaluation of Synthetic Medical Images

Authors: Sofia Beer, Menal Bhandari, Alec Block, Nader Darwish, Joseph Dingillo, Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Rajkumar Kettimuthu, Jason Patrick Luce, Ha Nguyen, John C. Roeske, George K. Thiruvathukal, Austin Yunker

Affiliation: Data Science and Learning Division, Argonne National Laboratory, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Computer Science, Loyola University of Chicago

Abstract Preview: Purpose: Artificial intelligence (AI) generated synthetic medical images are seeing increased use in radiology and radiation oncology. Physician observer studies are an ideal way to evaluate the usabi...

Feasibility of X-Ray Based Online Adaptive Dynamic Optimization with Integrated Knowledge-Based Planning for Head and Neck Cancer

Authors: Jacob S. Buatti, Mu-Han Lin, Dominic Moon, David D.M. Parsons, David Sher, Justin D. Visak, Hui Ju Wang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Most current adaptive treatment planning systems (TPS) natively utilize static planning goals from the reference plan for online adaptive re-optimization. In complex head-and-neck cancer (HNC...

Follow-the-Leader Framework for Adaptable Target Segmentation in Radiotherapy

Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: This study introduces a novel template-guided deep learning framework for primary gross tumor volume (GTVp) segmentation, addressing challenges posed by diverse tumor types and enabling a uni...

Fundamentals of Artificial Intelligence, Machine Learning and Deep Learning

Authors: Laurence Edward Court

Affiliation: Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: N/A...

Gradient-Based Radiomics for Outcome Prediction and Decision-Making in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR): A Preliminary Study

Authors: Michael Dohopolski, Jiaqi Liu, Hao Peng, Robert Timmerman, Zabi Wardak, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
This study introduces a gradient-based radiomics framework to enhance outcome prediction in Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR) for brain metastases...

Hands-on AI Education for Radiology Residents

Authors: Wilfred R Furtado, Gary Y. Ge, James Lee, Jie Zhang

Affiliation: University of Kentucky

Abstract Preview: Purpose: Despite advancements in Artificial Intelligence (AI) and its growing role in clinical practices like radiology, formal AI education remains limited in medical training. This gap contributes t...

Image Quality Enhancement for Transrectal Ultrasound Imaging of Prostate Brachytherapy Using Deep Learning: A Needle Eraser

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Serdar Charyyev, Xianjin Dai, PhD, Yu Gao, Thomas R. Niedermayr, Lei Xing

Affiliation: Department of Radiation Oncology, Stanford University

Abstract Preview: Purpose: Real-time transrectal ultrasound imaging is the gold standard for needle placement and treatment planning of real-time based-ultrasound-based high dose-rate (HDR) prostate brachytherapy. Cumu...

Impact of Artificial Intelligence on MR Imaging Quality and Acr Accreditations

Authors: Yuxiang Zhou

Affiliation: Mayo

Abstract Preview: N/A...

Incorporating Physicians’ Contouring Style into Auto-Segmentation of Clinical Target Volume for Post-Operative Prostate Cancer Radiotherapy Using a Language Encoder

Authors: Steve B. Jiang, Chien-Yi Liao, Dan Nguyen, Daniel Yang, Hengrui Zhao

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Post-operative radiotherapy for prostate cancer requires precise contouring of the clinical target volume (CTV) to account for microscopic disease that is invisible in the image. However, ...

Integrating Knowledge-Based Planning with Ethos 2.0 for High-Quality Online Adaptive Lung SABR

Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...

Inter-Patient Adaptive Radiotherapy (IPART): A CT Simulation and Planning Free Approach Enabling Immediate Treatment Access for Patients.

Authors: Bin Cai, Andrew R. Godley, Brian A. Hrycushko, Heejung Kim, Mu-han Lin, David D.M. Parsons, Justin D. Visak, Da Wang, Tingliang Zhuang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: The standard radiation therapy workflow requires CT-simulation and planning, whether for initial treatments or re-planning due to significant anatomical changes. IPART instead uses one patien...

Knowledge-Informed Deep Learning for Accurate and Interpretable Extracapsular Extension Detection in Head and Neck Squamous Cell Carcinoma

Authors: William N. Duggar, Amirhossein Eskorouchi, Haifeng Wang

Affiliation: Mississippi State University, University of Mississippi Medical Center

Abstract Preview: Purpose:
Extracapsular extension (ECE) in lymph nodes represents a critical prognostic factor in head and neck squamous cell carcinoma (HNSCC), bearing important implications for staging, treatment...

LLM-Enhanced Multi-Modal Framework for Predicting Pain Relief of Stereotactic Body Radiotherapy for Spine Metastases Using Clinical Factors and Imaging Reports

Authors: John Byun, Steven D Chang, Mingli Chen, Cynthia Chuang, Xuejun Gu, Melanie Hayden Gephart, Yusuke Hori, Hao Jiang, Mahdieh Kazemimoghadam, Fred Lam, Gordon Li, Lianli Liu, Weiguo Lu, David Park, Erqi Pollom, Elham Rahimy, Deyaaldeen Abu Reesh, Scott Soltys, Gregory Szalkowski, Lei Wang, Qingying Wang, Zi Yang, Xianghua Ye, Kangning Zhang

Affiliation: Department of Radiation Oncology, Stanford University, Department of Neurosurgery, Stanford University, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Accurate prediction of pain relief is crucial in determining the clinical effectiveness of Stereotactic body radiotherapy (SBRT) regimen for spine metastases. We propose a deep-learning frame...

Leveraging Codex-Based Spatial Profiling of the Tumor Microenvironment in Concurrent Radiation Therapy and Immunotherapy

Authors: Todd A Aguilera, Bassel Dawod, Sebastian Diegeler, Eslam Elghonaimy, Purva Gopal, Jiaqi Liu, Hao Peng, Arely Perez Rodriguez, Nina N. Sanford, Robert Timmerman, Megan B Wachsmann, Haozhao Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: This study pioneers the integration of CODEX (co-detection by indexing)-based spatial profiling and advanced computational techniques to investigate the tumor immune microenvironment (TIME) i...

Liver Tumor Auto-Contouring Using Recurrent Neural Networks on MRI-Linac for Adaptive Radiation Therapy

Authors: Yan Dai, Jie Deng, Christopher Kabat, Weiguo Lu, Ying Zhang, Hengrui Zhao

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
MRI-guided adaptive radiotherapy (MRgART) using MR-LINAC systems offers significant advantages for liver cancer, enabling superior tumor delineation and online plan adaptation. However, ma...

Lymph Node Malignancy Prediction in Head and Neck Cancer Using a Graph Neural Network

Authors: Liyuan Chen, Meixu Chen, Bowen Jing, Sepeadeh Radpour, Erich Josef Schmitz, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Prospective clinical trials have shown that involved nodal radiation therapy (INRT) can substantially improve patients’ quality of life without increasing the risk of elective nodal failure. ...

Maximizing Integrated Treatment Planning Tools to Increase Automation for X-Ray-Based Adaptive Lung Sabr

Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...

Medical Data Handler: A Research-Oriented Graphical User Interface for Dicom Processing, Image Analysis, and Data Management

Authors: Andrew R. Godley, Steve B. Jiang, Mu-Han Lin, Austen Matthew Maniscalco, Dan Nguyen, Yang Kyun Park

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Preparing DICOM datasets for research and education is challenging due to the complexity of the format and the necessity for patient-specific handling. Existing workflows demand substantia...

Mid-Range Planning for Efficient and Robust Proton Arc Therapy

Authors: Mingli Chen, Xuejun Gu, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Delivery efficiency and robustness are critical in spot-scanning proton arc therapy (SPAT), yet the conventional use of redundant energy layers (ELs) prolongs switching times and reduces effi...

Modeling the Future: Integrating Biology, AI, and Medical Physics in Personalized Radiation Therapy

Authors: Hao Peng

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: N/A...

Multi-Modality Artificial Intelligence for Involved-Site Radiation Therapy: Clinical Target Volume Delineation in High-Risk Pediatric Hodgkin Lymphoma

Authors: Tyler J Bradshaw, Sharon M Castellino, Steve Y Cho, David Hodgson, Bradford S Hoppe, Kara M Kelly, Andrea Lo, Sarah Milgrom, Xin Tie

Affiliation: Department of Radiation Oncology, University of Toronto, Department of Radiology, University of Wisconsin, University of Colorado Anschutz, Department of Medical Physics, University of Wisconsin, Department of Radiation Oncology, Mayo Clinic, Department of Radiation Oncology, BC Cancer, Vancouver Center, Department of Radiology, University of Wisconsin - Madison, Roswell Park Comprehensive Cancer Center, Emory University School of Medicine

Abstract Preview: Purpose: Clinical target volume (CTV) delineation for involved-site radiation therapy (ISRT) in Hodgkin lymphoma (HL) is time-consuming due to the need to analyze multi-time-point PET/CT scans co-regi...

Multi-Scale, Multi-Task Framework with Jacobian Descent for Multi-Plan Dose Prediction in Sequential Boost Radiotherapy

Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas

Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...

New Insights into Automatic Treatment Planning for Cancer Radiotherapy Using Explainable Artificial Intelligence.

Authors: Md Mainul Abrar, Yujie Chi

Affiliation: University of Texas at Arlington, Department of Physics, University of Texas at Arlington

Abstract Preview: Purpose: Healthcare 5.0, proposed in 2021, includes interpretable healthcare analysis as a core component. Achieving this requires the application of explainable artificial intelligence (XAI) to overc...

Nnae: Automating Anomaly Detection and Quality Assurance in Medical Image Segmentation

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Deep learning-based automatic medical image segmentation is increasingly employed in clinical practice, significantly reducing manual workload. However, verifying segmentation results rema...

Optimization of Impulsed Acquisition Protocols on 1.5T MRI Using Simulation-Based Bayesian Experimental Design for Cell Size Imaging

Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li, Junzhong Xu

Affiliation: Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiology, Vanderbilt University Medical Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cell size is a vital parameter in evaluating the tumor microenvironment, including cell apoptosis and radiotherapy(RT)-induced immune cell infiltration. The IMPULSED(Imaging Microstructural P...

Performance Comparison of Artificial Intelligence-Based Auto-Segmentation Software on Pediatric CT Image Datasets for the Creation of Patient Specific Computational Phantoms

Authors: Wesley E. Bolch, Emily L. Marshall, Dhanashree Rajderkar, Wyatt Smither

Affiliation: University of Florida

Abstract Preview: Purpose: To determine the accuracy of TotalSegmentator, an AI-based automatic segmentation toolkit, on pediatric CT scans as the original software was trained on adult image datasets with a mean patie...

Personalized Dosimetric Workflow for 177Lu-PSMA Treatments Considering the Cross-Irradiation from Bone Metastases to Red Bone Marrow

Authors: NadÚge Anizan, David Broggio, Désirée Deandreis, Didier Franck, Camilo Garcia, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard

Affiliation: Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, Gustave Roussy, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS

Abstract Preview: Purpose: This work aimed at developing an innovative workflow for 177Lu-PSMA personalized dosimetry to lesions and organs at risk (OAR) simultaneously, considering the cross-irradiation from bone meta...

Practical Techniques for Implementing New Technologies for Medical Physicists: Sittig and Singh’s Sociotechnical Model

Authors: Stephen F. Kry, Andrea Molineu

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center

Abstract Preview: Purpose: This study aims to introduce knowledge and tools from the fields of implementation science and change management to the medical physicist.
Methods: Medical physicists often implement new t...

Precision Radiotherapy Dose Prediction Using Foundation Model-Augmented Learning

Authors: Hilary P Bagshaw, Mark K Buyyounouski, Xianjin Dai, PhD, Praveenbalaji Rajendran, Lei Xing, Yong Yang

Affiliation: Department of Radiation Oncology, Stanford University, Massachusetts General Hospital, Harvard Medical School

Abstract Preview: Purpose: Artificial intelligence (AI)-driven methods have transformed dose prediction, streamlining the automation of radiotherapy treatment planning. However, traditional approaches depend exclusivel...

Predicting Pathological Complete Response to Neoadjuvant Chemotherapy for Breast Cancer at Early Time Points Using a Two-Stage Dual-Task Deep Learning Strategy

Authors: Bowen Jing, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Medical images acquired at multiple time points during neoadjuvant chemotherapy allow physicians to assess patients’ responses and personalize treatment plans accordingly. Studies from the I-...

Prediction of Head and Neck Cancer Using Artificial Neural Network through Basic Health Data

Authors: Abdullah Hidayat, Wazir Muhammad

Affiliation: Florida Atlantic University

Abstract Preview: Purpose: This study aims to predict Head and Neck cancer using an artificial neural network (ANN) through readily available basic health data. The goal is to uncover hidden patterns and predictors in ...

Principles of Medical Imaging: An AI-Driven Interdisciplinary Course Bridging Academia, Industry, and Clinical Practice

Authors: Ning Wen, Zheyu Zhang

Affiliation: Department of Radiology, Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai Jiaotong University

Abstract Preview: Purpose: The graduate course, “Principles of Medical Imaging,” aims to advance imaging technology by integrating artificial intelligence (AI) into medical imaging. It bridges interdisciplinary fields,...

Prior-Adapted Progressive Motion-Resolved CBCT Reconstruction Using a Dynamic Reconstruction and Motion Estimation Method

Authors: Hua-Chieh Shao, You Zhang, Ruizhi Zuo

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cone-beam CT (CBCT) provides on-board patient anatomy for image guidance and treatment adaptation in radiotherapy. However, to compensate for respiration-induced anatomical motion, motion-res...

Prior-Model-Free Dynamic CBCT Reconstruction Via Combined Optical Surface and X-Ray Imaging

Authors: Hua-Chieh Shao, Guoping Xu, You Zhang, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Advancements in onboard X-ray hardware allow high-quality CBCT imaging with a short scan time (~6s for Varian HyperSight), enabling CBCT-based dose calculation and treatment planning. Howe...

Quantitative CBCT in Clinical Application

Authors: Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: N/A...

Real-Time 3D Dose Verification for MR-Guided Online Adaptive Radiotherapy (ART) Via Geometry-Encoded Deep Learning Framework

Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Fast dose verification is essential for the safety and efficiency of MR-guided adaptive radiotherapy (ART) as patients anxiously waiting on the treatment couch. Conventional tools often requi...

Real-Time Automatic Treatment Planning System (RT-AutoTPS) for Volumetric Modulated Arc Radiotherapy (VMAT)

Authors: Steve B. Jiang, Austen Matthew Maniscalco, Dan Nguyen, Chenyang Shen, Jiacheng Xie, Shunyu Yan, Ying Zhang, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas

Abstract Preview: Purpose: Although treatment planning systems (TPSs) can handle dose calculation and plan optimization automatically, planning for radiotherapy still requires extensive efforts and expertise from a mul...

Robust Estimation of Cell Microstructure Parameters Via Diffusion MRI Cytometry

Authors: Yan Dai, Jie Deng, Xun Jia, Wen Li

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Cell microstructure information is critical for radiotherapy response assessment. Diffusion MRI (dMRI) offers great potential in deriving cell parameters. Yet parameters estimated in existing...

Safety and QA Considerations of Synthetic Images

Authors: Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: N/A...

Simultaneous Motion Estimation and Image Reconstruction with Spatiotemporal Implicit Neural Representation Initial (STINR-SMEIR) for Gas Bubble Motion Artifact Reduction in on-Board CBCT Imaging

Authors: Hua-Chieh Shao, Shanshan Tang, Jing Wang, Kai Wang, You Zhang

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, University of Maryland Medical Center

Abstract Preview: Purpose: Artifacts caused by gas bubble movement in the gastrointestinal tract can severely degrade the image quality of on-board abdominal cone-beam computed tomography (CBCT), impacting its utility ...

Small Fields Output Factor Measurements in 1.5 MR-Linac

Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...

Spatially Aware Radiomics Integrating Anatomical Knowledge to Improve Lymph Node Malignancy Prediction in Head and Neck Cancer

Authors: Liyuan Chen, Sepeadeh Radpour, David Sher, Jing Wang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center

Abstract Preview: Purpose: Accurate lymph node malignancy prediction is pivotal in optimizing radiation treatment strategies for head and neck (HN) cancer patients. While conventional radiomics models leverage intensit...

Teaching an Old Dog New Tricks: Unlocking Hidden Potential in Existing Frameworks for Versatile Radiotherapy Applications

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
This work demonstrates how existing software, when creatively adapted, can address a wide range of clinical challenges. By focusing on data exploration and application-specific modificatio...

The Effect of CT Reconstruction Kernel and Slice Thickness on AI-Based CAD Measurement of Hypodense Volume and Aspects Value for Stroke Evaluation in Non-Contrast Head CT.

Authors: Matthew S Brown, John M. Hoffman, William Hsu, Grace Hyun Kim, Michael F. McNitt-Gray, Spencer Harrison Welland, Anil Yadav

Affiliation: Department of Bioengineering, UCLA, David Geffen School of Medicine at UCLA, UCLA Department of Radiology

Abstract Preview: Purpose: Non-contrast CT (NCCT) is frequently used in initial evaluation of suspected stroke to rule out intracerebral hemorrhage. Quantitative scoring systems like the Alberta Stroke Program Early CT...

Towards AI-Driven Adaptive Radiotherapy: Developing a Framework for Utilizing Large-Vision Models in Head-and-Neck Cancer Treatment.

Authors: Anthony J. Doemer, Bing Luo, Benjamin Movsas, Humza Nusrat, Farzan Siddiqui, Chadd Smith, Kundan S Thind, Kyle Verdecchia

Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health

Abstract Preview: Purpose: Large-vision models (LVMs) are rapidly emerging, yet their application in radiation oncology remains largely unexplored. This study investigates the potential of LVMs for offline adaptive rad...

Uncertainty-Guided Cross-Domain Adaptation for Unsupervised Medical Image Segmentation

Authors: Yunxiang Li, Weiguo Lu, Xiaoxue Qian, Hua-Chieh Shao, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Curating high-quality, labeled data for medical image segmentation can be challenging and costly, considering the existence of various image domains with differing modalities/protocols. Cr...

Unidose: A Universal Framework for IMRT Dose Prediction

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Zi Yang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose: Dose prediction (DP) is essential in guiding radiotherapy planning. However, current DP models for intensity-modulated radiation therapy (IMRT) primarily rely on fixed-beam orientations and a...

Universal Anatomical Mapping and Patient-Specific Prior Implicit Neural Representation for MRI Super-Resolution

Authors: Jie Deng, Yunxiang Li, You Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose: Magnetic Resonance Imaging (MRI) has exceptional soft tissue contrast and an essential role in radiotherapy. The introduction of clinical MR-LINACs has enabled adaptive radiotherapy (ART) usi...

Universal MR-to-Synthetic CT: A Streamlined Framework for MR-Only Radiotherapy Planning

Authors: Mingli Chen, Xuejun Gu, Hao Jiang, Mahdieh Kazemimoghadam, Weiguo Lu, Qingying Wang, Kangning Zhang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine

Abstract Preview: Purpose:
Converting MR images to synthetic CT (MR2sCT) is highly desirable as it streamlines the radiotherapy treatment planning workflow. This approach leverages the superior soft tissue visibilit...

Unsupervised Task-Specific Histology Image Stain Standardization and Crypt Detection for Evaluating Normal Tissue Flash Irradiation Response

Authors: Muhammad Ramish Ashraf, Kerriann Casey, Suparna Dutt, Jie Fu, Edward Elliot Graves, Xuejun Gu, Hao Jiang, Brianna Caroline Lau, Billy W Loo, Weiguo Lu, Rakesh Manjappa, Stavros Melemenidis, Erinn Bruno Rankin, Lawrie Skinner, Luis Armando Soto, Murat Surucu, Vignesh Viswanathan, Zi Yang, Amy Shu-Jung Yu

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, Stanford University School of Medicine, Department of Comparative Medicine, Stanford University School of Medicine, Department of Radiation Oncology, Stanford University Cancer Center

Abstract Preview: Purpose: The intestine is a classical preclinical model for studying radiation injury, and histological quantification of intestinal crypts is a key assay for assessing this response. However, substan...

Using a Generative Adversarial Network (GAN) for Source Particle Generation in Monte Carlo Radiation Therapy Simulations

Authors: Jiankui Yuan, Dandan Zheng, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, University of Rochester, Varian Medical Systems, Advanced Oncology Solutions

Abstract Preview: Purpose: In Monte Carlo (MC) radiation therapy dose calculations, latent variance exists when directly applying phase-space files (PSF) with a finite number of source particles, while the latter is pr...

“See” through Surface: Transforming Surface Imaging into a Real-Time Three-Dimensional Imaging Solution for Intra-Treatment Image Guidance

Authors: Steve B. Jiang, Ruiqi Li, Hua-Chieh Shao, Kenneth Westover, You Zhang, Tingliang Zhuang

Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center

Abstract Preview: Purpose:
Respiratory motion is a long-standing challenge for lung SBRT, particularly for centrally-located lung tumors where increased toxicity demands more precise motion management during treatme...