Authors: John Paul Ortiz Bustillo, Elette Engels, Elrick T. Inocencio, Michael Lerch, Julia Rebecca D Posadas, Anatoly Rosenfeld, Kiarn Roughley, Moeava Tehei, Gordon Wallace, Danielle Warren, Vincent de Rover
Affiliation: Centre for Medical Radiation Physics, University of Wollongong Australia, Department of Radiology, University of the Philippines- Philippine General Hospital, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong Australia, Centre for Medical Radiation Physics, University of Wollongong, Intelligent Polymer Research Institute, ARC Centre of Excellence for Electromaterials Science, AIIM Facility, University of Wollongong, University of the Philippines Manila; Centre for Medical Radiation Physics, University of Wollongong Australia
Abstract Preview: Purpose: To compare the biological response through cell viability assay and fluorescence imaging of 3D bioprinted brain cancer (glioma) constructs relative to 2D monolayer and 3D spheroid culture for...
Authors: Shashanksharad Kale, Gopishankar Natanasabapathi, Daya Nand Kishore Sharma
Affiliation: All India Institute of Medical Sciences (AIIMS), Department of Radiation Oncology, All India Institute of Medical Sciences
Abstract Preview: Purpose:
The study demonstrates a novel 3D printing method to fabricate an ion chamber insert (ICI) for absolute dosimetry purpose in gamma knife radiosurgery (GKRS).
Methods:
Our institute u...
Authors: Arpit M. Chhabra, J Isabelle Choi, Minglei Kang, Haibo Lin, Hang Qi, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Xingyi Zhao, Ajay Zheng
Affiliation: New York Proton Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Pencil beam scanning (PBS) proton therapy effectively treats ocular cancer by minimizing exit doses to normal tissues. However, challenges remain in sparing nearby organs-at-risk(OARs). Ul...
Authors: Jie Deng, Xiaoxue Qian, Hua-Chieh Shao, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Based on a 3D pre-treatment MRI scan, we developed DREME-MR to jointly reconstruct the reference patient anatomy and a data-driven, patient-specific cardiorespiratory motion model. Via a moti...
Authors: William N. Duggar, Li Yuan
Affiliation: University of Mississippi Medical Center
Abstract Preview: Purpose:
Radiation Oncology departments typically utilize various systems from different vendors. Ensuring the integrity and correctness of data during transfers between these systems is essential ...
Authors: Benjamin R. Awad, Bulent Aydogan, Howard J Halpern, Erik Pearson, Gage H. Redler, Jordan M. Slagowski, Rajit Tummala, Autumn E. Walter-Denzin, Jimmy Zydlo
Affiliation: University of Wisconsin-Madison Department of Human Oncology, University of Oxford, The University of Chicago, Moffitt Cancer Center, California State University, Fresno, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Small animal models are crucial in cancer research to develop, validate, and translate basic scientific hypotheses into clinical advancements. This study aims to make small animal intensity-m...
Authors: Xiangli Cui, Man Hu, Wanli Huo, Da Yao, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Department of Oncology, Xiangya Hospital, Central South University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose:
To study the fine-tuning strategy of pre-trained AI image generation model to adapt to the generation of small sample meningioma MRI images, explore its impact on observer performance, and...
Authors: John P. Aris, Wesley E. Bolch, Robert Joseph Dawson, Bonnie N. C. President, Yitian Wang
Affiliation: Johns Hopkins University, University of Florida
Abstract Preview: Purpose: Generation of a mesh-based microscale lung model is essential for accurate dosimetry analysis. Lungs exchange air with the environment and may be exposed to alpha-particle-emitting radionucli...
Authors: Kostas Danniidis, Agelos Kratimenos, Yufu Wang, Timothy C. Zhu, Yifeng Zhu
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: This study aims to develop software and algorithms utilizing artificial intelligence (AI) to seamlessly create 3D patient postures during Total Skin Electron Therapy (TSET). The resulting mes...
Authors: Anna Becker, Tomislav Bokulic, Mauro Carrara, Krzysztof Chelminski, Larry A. DeWerd, Alexis Dimitriadis, Benjamin Kellogg, Malcolm R. McEwen, Zakithi L.M Msimang, Mark J. Rivard, Thorsten Sander, Thorsten Schneider, Jamema Swamidas, Egor Titovich, Paula Toroi, Carlos E. de Almeida, Jacco de Pooter, Liset de la Fuente Rosales, Deborah G. van der Merwe
Affiliation: Radiation and Nuclear Safety Authority, University of Zagreb, National Physical Laboratory, IAEA, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Rio de Janeiro State University, Dosimetry Laboratory, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, Physikalisch-Technische Bundesanstalt, National Metrology Institute, University of the Witwatersrand, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, National Research Council, Warren Alpert Medical School of Brown University
Abstract Preview: Purpose: The recently published IAEA-TRS-492 international code of practice (CoP) aims at improving traceability, accuracy, and consistency in Brachytherapy Dosimetry. To assess current approaches to ...
Authors: Ashley Cetnar
Affiliation: The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: Undergraduate students are eager to learn more about potential career opportunities. While many physics majors are aware of research opportunities within the physics department, students may ...
Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Maximilian Stephen Meineke, Runhe Tan
Affiliation: The James Cancer Center, The Ohio State University, The Ohio State University - James Cancer Hospital
Abstract Preview: Purpose: The response of healthy vasculature due to radiation treatments is an underexplored area of radiation oncology. Understanding the impact of radiation on veins could advance treatment optimiza...
Authors: Petr Bruza, Jeremy Eric Hallett, Brian W Pogue
Affiliation: Thayer School of Engineering, Dartmouth College, University of Wisconsin - Madison, University of Wisconsin-Madison
Abstract Preview: Purpose: Cherenkov imaging is a powerful tool for localizing entrance and exit dose during radiotherapy treatment. The current implementation uses an intensified-CMOS (iCMOS) camera allowing for high-...
Authors: Ashish Binjola, Raj Kishore Bisht, Natanasabapathi Gopishankar, Pratik Kumar, Daya Nand Kishore Sharma, Sukhvir Kishore Singh, Subramani Vellaiyan
Affiliation: Medical Physics Unit, All India Institute of Medical Sciences, All India Institute of Medical Sciences, Department of Radiological Safety, Institute of Nuclear Medicine and Allied Sciences, Department of Radiation Oncology, All India Institute of Medical Sciences
Abstract Preview: Purpose: Additive manufacturing is increasingly being explored to create dosimetry phantoms. Commercial anthropomorphic phantoms represent an average patient and lack anatomical variations due to obes...
Authors: Yankun Lang, Lei Ren, Dario B. Rodrigues
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose:
HTP of microwave (MW) phased-array systems determine MW antenna settings to maximize energy absorption (SAR in W/kg) in tumor. Conventional HTP algorithms calculate SAR based on electromag...
Authors: Eduardo Florian, Hiram Gay, Geoffrey D. Hugo, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Francisco Javier Reynoso, Edgar Aparicio Ruiz, Baozhou Sun, Jacaranda Van Rheenen, Kevin Vega, Angel Velarde, Vicky de Falla
Affiliation: WashU Medicine, Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Washington Univ. in St. Louis, Liga Nacional Contra el Cáncer / INCAN, Washington University in St. Louis, Varian, Baylor College of Medicine
Abstract Preview: Purpose:
IMRT has become the standard of care in high-income countries (HICs) due to reduced toxicity and improved treatment outcomes.
The purpose of this work is validating the KBP model shared...
Authors: Rodrigo Delgadillo, Nesrin Dogan, Benjamin J. Rich, Stuart E Samuels, Levent Sensoy
Affiliation: University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Daily Cone beam CT (CBCT) images may be useful in detecting early morphological changes during head and neck cancer radiotherapy. The aim of this study was to evaluate the performance of CBCT...
Authors: Brian Burger, Carri K. Glide-Hurst, John W. Hayes, Carson Hoffman, Minglei Kang, Jessica R. Miller, Jordan M. Slagowski, Yuhao Yan
Affiliation: Department of Human Oncology, University of Wisconsin-Madison, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Leo Cancer Care
Abstract Preview: Purpose: The combination of upright CT and patient positioner for particle therapy present tremendous potential for high precision IGRT and online adaptive radiation therapy (ART), where reliable CT p...
Authors: Sam Armstrong, Jamison Louis Brooks, Nicole Johnson, Douglas John Moseley, Cassie Sonnicksen, Erik J. Tryggestad
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To evaluate the feasibility of a shallow learning-based quality assurance (QA) tool designed to assist human reviewers in assessing organ-at-risk (OAR) contours for head and neck radiotherapy...
Authors: Christopher A. Aguilera, Hunter Tillery, Cheyann Windsor
Affiliation: Oregon Health & Science University, Northwest Medical Physics Center
Abstract Preview: Purpose: To demonstrate a method of acquiring 4DCT commissioning datasets for deviceless 4DCT which relies on an image-based algorithm instead of an external breathing signal for 4D image binning. The...
Authors: Mauro Carrara, Olivera Ciraj Bjelac, John E. Damilakis, Andre L. Dekker, Serafina Di Gioia, Renato Padovani, Egor Titovich, Qingrong Jackie Wu
Affiliation: University of Crete, Duke University Medical Center, Maastro Clinic, Dosimetry and Medical Radiation Physics Section, Division of Human Health, International Atomic Energy Agency, International Centre for Theoretical Physics
Abstract Preview: Purpose: The purpose of this work is to present the International Atomic Energy Agency (IAEA) activity in providing medical physicists (MPs) with knowledge, skills, and competencies to support the saf...
Authors: Fumiaki Komatsu, Shunsuke Moriya, Ryosuke Nakamura, Takeji Sakae, Toshiyuki Terunuma, Tetsuya Tomita
Affiliation: Graduate School of Comprehensive Human Sciences, University of Tsukuba, Institute of Medicine, University of Tsukuba, Proton Medical Research Center, University of Tsukuba, Department of Radiology, University of Tsukuba Hospital
Abstract Preview: Purpose: To develop a deep learning (DL) model capable of accurately tracking lung tumors independent of beam angle variations.
Methods: A thoracic dynamic phantom simulating lung motion in the sup...
Authors: Dirk Grunwald, Hans Herzog, Hidehiro Iida, N. Jon Shah, Usman Khalid, Manfred Lennartz, Philipp Lohmann, Ceren Memis, Tobias Meurer, Claudia Regio Brambilla, Jürgen Scheins, Lutz Tellmann, Christoph W. Lerche, Martin Wiesmann, Karl Ziemons
Affiliation: FH Aachen University of Applied Sciences, Department of Chemistry and Biotechnology, Clinic for Diagnostic and Interventional Neuroradiology, Uniklinik Aachen,, Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medicine (INM-4), Forschungszentrum Jülich GmbH,, Central Institute for Engineering, Electronics and Analytics (ZEA-1), Forschungszentrum, Turku PET Center, Institute of Biomedicine, Faculty of Medicine, University of Turku,
Abstract Preview: Purpose: Quantitative brain studies with positron emission tomography (PET) often require an arterial input function (AIF), which traditionally requires arterial cannulation. However, this is invasive...
Authors: Alejandro Bertolet, Isaac Meyer, Harald Paganetti, Jan PO Schuemann, Wook-Geun Shin
Affiliation: Massachusetts General Hospital, Massachusetts General Hospital and Harvard Medical School
Abstract Preview: Purpose: To develop a methodology for Monte Carlo modeling of cell-specific DNA geometries based on Hi-C data using TOPAS-nBio, and to evaluate early DNA damage distributions.
Methods: Hi-C data of...
Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav
Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)
Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop and validate an Eclipse Scripting Application Programming Interface (ESAPI)-based planning toolbox that incorporates preset human expertise to improve planning e...
Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma
Affiliation: University of Pennsylvania, Mayo Clinic
Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...
Authors: Christoph Bert, Leon Brückner, Luitpold Distel, Julian Freier, Peter Hommelhoff, Bastian Löhrl
Affiliation: Department of Radiation Oncology, Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Department Physik, Friedrich-Alexander Universität Erlangen-Nürnberg
Abstract Preview: Purpose: Low energy electron (LEE) bunches in the kilo electronvolt (keV) range are thought to have a high relative biological effectiveness (RBE). To investigate this, it is necessary to establish re...
Authors: Lotem Buchbinder Shadur, Shaheen Dewji, Martin Graffigna, Alejandro Rafael Martinez, Emmanuel Mate-Kole, Antonio McClain, Samuel Taylor, Jeffrey Wang
Affiliation: Student, Nuclear and Radiological Engineering and Medical Physics Programs, Georgia Institute of Technology
Abstract Preview: Purpose: DosInMe is an internal dosimetry visualization tool developed by the Radiological Engineering, Detection, and Dosimetry Laboratory at Georgia Tech to assist researchers and professionals in v...
Authors: Kristina Bjegovic, Yong Chen, Lucia Rodriguez Gonzalez, Marti Roper, Liangzhong Xiang
Affiliation: University of California, Irvine, University of California Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is an increasingly popular cancer treatment due to its precision, enabled by the Bragg Peak (BP), which minimizes side effects. This profile necessitates in-patient localizatio...
Authors: Jia Jing, Hui Lin, Daming Meng, Zhenyu Xiong
Affiliation: School of Physics, Hefei University of Technology, Rutgers Cancer Institute of New Jersey
Abstract Preview: Purpose: Artificial intelligence (AI) is attempting to understand the essence of intelligence and produce a new type of intelligent machine that can respond in a way similar to human intelligence. AI ...
Authors: Jongduk Baek, Jooho Lee, Adam S. Wang
Affiliation: Stanford University, Yonsei University
Abstract Preview: Purpose: Optimizing the balance between radiation dose and image quality in computed tomography (CT) is important for minimizing patient X-ray exposure while maintaining diagnostic accuracy. While rad...
Authors: John Ford, Yu Fujiwara, Isao Murata, Zavier Ndum Ndum
Affiliation: Osaka University, Texas A&M University
Abstract Preview: Purpose: This study investigates how particle energy affects radiation quality and biological effectiveness with the inclusion of medical implants. Our research group used microdosimetric analysis to ...
Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda
Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...
Authors: Kenneth A. Fetterly
Affiliation: Mayo Clinic
Abstract Preview: Purpose: Among the limitations of channelized Hotelling T2 type model observers (CHO) applied to medical imaging systems is that they reduce 2D image detail to a singular value and are only applicable...
Authors: Blessing Chinelo Akah, Daniel W. Neck, David J. Perrin, Sotirios Stathakis
Affiliation: Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: To assess the reliability of the Aktina Isopoint software in evaluating different components of the linear accelerator for optimized quality assurance and linac performance
Methods: The Ak...
Authors: Meiyun Cao, Edward L. Clouser, Xiaoning Ding, Jason Michael Holmes, Shaw Hu, Linda L. Lam, Wendy S. Lindholm, Wei Liu, Samir H. Patel, Diego Santos Toesca, Jason Sharp, Sujay A. Vora, Peilong Wang
Affiliation: Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, George Washington University
Abstract Preview: Purpose: In current clinical workflow of radiation oncology departments, therapists manually summarize CT simulation orders into summaries before the CT simulation for execution. This process signific...
Authors: Haleem Azmy, Robbie Beckert, Farnoush Forghani, Dean Hobbis, Dan Hong, Hyun Kim, Eric Laugeman, Silpa Raju-Salicki, Domenic Sievert
Affiliation: Washington University in St. Louis School of Medicine, WashU Medicine, Washington University School of Medicine, Department of Radiation Oncology, Washington University School of Medicine in St. Louis, Washington University School of Medicine, Wash U Medicine, Washington University in St. Louis
Abstract Preview: Purpose: A novel radiation therapy (RT) workflow has recently emerged with the advent of online adaptive RT systems, direct-to-unit (DTU). DTU utilizes online adaptive platforms (MR and CT based) to o...
Authors: Victoria Noelle Bry, Tamara Egan, Eric C. Ford, Angelia Landers, Juergen Meyer
Affiliation: Fred Hutch Cancer Center, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, University of Washington
Abstract Preview: Purpose: Surface guided radiation therapy (SGRT) can improve patient safety, however, its complex integration may expose processes to increased risk of error. This work identifies potential failures f...
Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Wagner Henrique Marques, Raphael Morata, Victor H.F Oliveira
Affiliation: University of São Paulo (USP), Institute of Physics
Abstract Preview: Purpose: This study investigates the feasibility of 3D printing materials in creating anthropomorphic kidney phantoms that accurately simulate the radiological properties of human tissues, for applica...
Authors: Xiangli Cui, Chunyan Fu, Man Hu, Wanli Huo, Jingyu Liu, Jianguang Zhang, Yingying Zhang, Shanyang Zhao
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University, Departments of Radiation Oncology, Zibo Wanjie Cancer Hospital, Key Laboratory of Electromagnetic Wave Information Technology and Metrology of Zhejiang Province, College of Information Engineering, China Jiliang University, Department of Oncology, Xiangya Hospital, Central South University, College of Information Engineering, China Jiliang University, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences
Abstract Preview: Purpose: To quantify the impact of fine-tuning strategies for pre-trained AI image generation models on glioma MRI image quality and observer performance, and to determine the optimal fine-tuning conf...
Authors: Xu Cao, Wesley S. Culberson, Aleksandra Ilina, Kendall Jarvis, Brian W Pogue, Matthew Reed, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison
Abstract Preview: Purpose: While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR). Currently it is not clear whether this ...
Authors: Michelle Alonso-Basanta, Carl Denis, Wenbo Gu, Xinmin Liu, Ahmad Sakaamini, Rodney D. Wiersma
Affiliation: UCLA, University of Pennsylvania, CDR Systems
Abstract Preview: Purpose: Stereotactic radiosurgery (SRS) is a non-invasive technique used to treat functional abnormalities and small brain tumors. Traditional SRS relies on a rigidly fixed metal head ring, causing d...
Authors: Yasin Abdulkadir, John Charters, Melissa Ghafarian, James M. Lamb, Dishane Chand Luximon, Jack Neylon
Affiliation: Department of Radiation Oncology, University of California, Los Angeles
Abstract Preview: Purpose:
Assessment of radiotherapy treatment quality in large-scale multi-institutional contexts remains an outstanding challenge. Retrospective human review of treatment plans is labor intensive ...
Authors: Hamid Abdollahi Nasehabad, Mehrangiz Amiri, Mohammad Reza Deevband, Faraz Kalantari, Milad Peer-Firozjaei, Ali Shabestani Monfared, Ehsan Tajikmansoury
Affiliation: Biomedical Engineering and Medical Physics Department, School of Medicine, Shahid Beheshti University of Medical Sciences, Department of Radiology, University of British Columbia, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, 1. Department of Radiobiology and Medical Physics, Babol University of Medical Sciences, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine
Abstract Preview: Purpose:
Targeted radionuclide therapy (TRNT) with 213Bi- labeled radiopharmaceuticals is a promising approach in targeted alpha and beta therapy for cancer. This study aims to assess double-strand...
Authors: Peng Dong, Elizabeth Kidd, Sheng Liu, Thomas R. Niedermayr, Oscar Pastor-Serrano, Lei Xing, Yong Yang, James Zou
Affiliation: Department of Biomedical Data Science, Stanford University, Department of Radiation Oncology, Stanford University, Stanford University
Abstract Preview: Purpose: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires iterative adjustments of optimization parameters to balance conflicting objectives. In thi...
Authors: Adnan Jafar, Xun Jia, An Qin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose: 3D whole-brain radiotherapy (WBRT) is widely used due to its simplicity and effectiveness. While modern treatment planning systems, like RayStation, offer automated Field-in-Field planning, p...
Authors: Cecelia Brewington, Connor Edwards Miles All Leska-Kent, Kyrillos Grace, Katherine Hyde, Sabee Molloi, Shiva Mostafavi, Liqiang Ren, Alireza Shojazadeh, Justin Truong
Affiliation: Department of Radiology, UT Southwestern Medical Center, University of California, Irvine, University of Texas Southwestern
Abstract Preview: Purpose: To retrospectively assess image quality in coronary CT angiography (CCTA) using a patient-specific post-trigger delay (PTD) protocol, developed using half of the injection time plus a dispers...
Authors: Muhammed AR Anjum, Andrew J. Fagan
Affiliation: Mayo Clinic
Abstract Preview: Purpose:
This study describes a novel post-processing method to boost image SNR for deuterium-MRI acquired using chemical shift imaging (CSI) at 7T. Deuterium MRI via exogenous administration of a ...
Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...
Authors: Zong Fan, Fan Lam, Hua Li, Rita Huan-Ting Peng, Yuan Yang
Affiliation: University of Illinois at Urbana Champaign, University of Illinois at Urbana-Champaign, Washington University School of Medicine, University of Illinois Urbana-Champaign
Abstract Preview: Purpose: Accurate lesion segmentation in MRI is critical for early diagnosis, treatment planning, and monitoring disease progression in various neurological disorders. Cross-site MRI data can alleviat...
Authors: Lili Chen, Dusica Cvetkovic, Tristan K. Gaddis, Chang Ming Charlie Ma, Dae-Myoung Yang
Affiliation: Fox Chase Cancer Center
Abstract Preview: Purpose:
Recent studies have shown that combining photosensitizers with radiation therapy can enhance tumor control while reducing damage to normal tissues, a technique known as Radiodynamic Therap...
Authors: Amar K. Basavatia, Lee C. Goddard, Wolfgang A. Tomé, Christian Velten, Ping Yan, Ravindra Yaparpalvi, Maria Stefania diMayorca
Affiliation: Montefiore Medical Center
Abstract Preview: Purpose: High dose rate (HDR) brachytherapy planning is a high-risk procedure performed under significant time pressure, with human failure being the leading cause of error. To elevate training for me...
Authors: Stewart J. Becker, Andrew Genuit, Mariana Guerrero, Yannick P. Poirier
Affiliation: University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: To introduce an additional quality assurance step to prevent human error in vial mix-ups during Yttrium-90 (Y90) radioembolization by verifying the local assay at the time of delivery. We pro...
Authors: Justus Adamson, John Ginn, Yongbok Kim, Ke Lu, Trey Mullikin, Xiwen Shu, Chunhao Wang, Zhenyu Yang, Jingtong Zhao
Affiliation: Duke University, Duke Kunshan University
Abstract Preview: Purpose:
To develop a knowledge-based deep model for synthetic CT (sCT) generation from a single MR volume in frameless radiosurgery (SRS), eliminating the need for CT simulation prior to the SRS d...
Authors: Gregory A Azzam, Michael Butkus, Nesrin Dogan, Robert Kaderka, Nhan Vu, Yihang Xu
Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center, University of Miami, Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) has demonstrated potential for improving planning quality and efficiency. Adoption of KBP in particle therapy has been slow due to limited number of plans to tr...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Wesley S. Culberson, Albert Du, Ryan T. Flynn, Ryan Gardner, Alonso N. Gutierrez, Patrick M Hill, Daniel E. Hyer, Eric Jensen, Kaustubh A. Patwardhan, Blake R. Smith, Nhan Vu, Karsten K. Wake
Affiliation: University of Wisconsin, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Miami Cancer Institute, Baptist Health South Florida, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Ion Beam Applications (IBA), University of Iowa, Iowa Health Care
Abstract Preview: Purpose: To develop an accurate predictive temporal model for the movement of Dynamic Collimation System (DCS) trimmers during collimated proton pencil beam scanning (PBS) deliveries using log data. T...
Authors: Nina Burbure, Tawfik G. Giaddui, Shidong Li, Curtis Miyamoto, Jeremy Price, Bin Wang
Affiliation: FCCC at Temple University Hospital
Abstract Preview: Purpose: To evaluate the performance of KBP models for hypo-fractionated prostate and pelvic lymph nodes (LN) VMAT plans.
Methods: A KBP model (TUH KBP) was developed in Eclipse treatment planning ...
Authors: Alyssa Capizzi, John J Dombrowski, Nabil N. Khater
Affiliation: Saint Louis University
Abstract Preview: Purpose: To evaluate a mask-less adaptable headrest (MAHR) prototype for head-and-neck IMRT designed to reduce random and systematic shifts of patients’ setups. MAHR complements current image-guidance...
Authors: Afrouz Ataei, Xinhui Duan, Mi-Ae Park, Liqiang Ren
Affiliation: Department of Radiology, UT Southwestern Medical Center, UT Southwestern Medical Center, Rush University
Abstract Preview: Purpose:
Photon-counting CT (PCCT) has become commercially available recently, offering significant potential to enhance patient care. However, it also introduces unique challenges. One such challe...
Authors: Joseph A. Moore, Paul Rothweiler, Jussi K. Sillanpaa, Adhvaith Sridhar
Affiliation: University of Minnesota
Abstract Preview: Purpose: To investigate 3D printed human tissue simulant phantoms for use in radiation therapy and to quantify the mechanical and radiation properties of these phantoms.
Methods: We designed and 3D...
Authors: John P. Aris, Wesley E. Bolch, Chansoo Choi, Carlos G. Colon-Ortiz, Robert Joseph Dawson, Abdul-Vehab Dozic, Amy M. Geyer, Harald Paganetti, Shreya P. Pathak, Julia D. Withrow
Affiliation: St. Luke's Health System, Massachusetts General Hospital, University of Florida
Abstract Preview: Purpose: The goal of this study was to enhance the accuracy of renal dosimetry in radiopharmaceutical therapy (RPT) by developing a more detailed and precise kidney model. In RPT, accurate dose estima...
Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...
Authors: Kevin M Brom, Josep Chorro Bas, RosaAnna Chorro Bas, Andres Climent Rubio, Jaydev K. Dave, Tobias Kummer, Larissa Shiue, Donald J Tradup
Affiliation: Mayo Clinic, Prehospital Critical Care Training Group
Abstract Preview: Purpose: To design and evaluate the functionality of a vascular flow phantom for contrast-enhanced ultrasound imaging (CEUS).
Methods: A microcontroller-generated signal was amplified by a cust...
Authors: Zhongjie Lu
Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine
Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...
Authors: Malvern Madondo, Mark McDonald, Zhen Tian, Christopher Valdes, Ralph Weichselbaum, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Emory University, Department of Radiology, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Head-and-neck (HN) cancer patients often experience significant anatomical changes during treatment course. Proton therapy, particularly intensity-modulated proton therapy (IMPT), is sensitiv...
Authors: Wesley S. Culberson, Aleksandra Ilina, Brian W Pogue, Matthew Reed, Connor Strainis, William Scott Thomas, Nathaniel Van Asselt, Albert van der Kogel
Affiliation: University of Wisconsin: Madison, University of Wisconsin: Madison School of Veterinary Medicine, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin–Madison, University of Wisconsin-Madison, University of Wisconsin - Madison
Abstract Preview: Purpose: FLASH radiotherapy reduces skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), while preserving damage to tumor tissue. The FLASH effec...
Authors: Kristina Bjegovic, Yong Chen, Gilberto Gonzalez, Yankun Lang, Lei Ren, Leshan Sun, Liangzhong Xiang, Yifei Xu
Affiliation: University of Maryland School of Medicine, University of California, Irvine, University of Oklahoma Health Sciences Center, University of Oklahoma Health Science Center
Abstract Preview: Purpose: Proton therapy is becoming an increasingly popular choice for cancer treatment due to its precision, reduced side effects, and effectiveness. While dosimetry is fundamental to the success of ...
Authors: Stephen F. Kry, Andrea Molineu
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center
Abstract Preview: Purpose: This study aims to introduce knowledge and tools from the fields of implementation science and change management to the medical physicist.
Methods: Medical physicists often implement new t...
Authors: Qianxi Ni, Qionghui Zhou
Affiliation: The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University
Abstract Preview: Purpose:
This study aims to develop and evaluate interpretable machine learning models that use radiomic and dosimetric features to predict HT in advanced cervical cancer patients.
Methods:
R...
Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...
Authors: Richard Bakst, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Minglei Kang, Nancy Y Lee, Haibo Lin, Hang Qi, Charles B. Simone, Pingfang Tsai, Milo Vermeulen, Shouyi Wei, Xiaodong Wu, Lee Xu, Irini Yacoub, Xingyi Zhao, Ajay Zheng
Affiliation: University of Miami, Peking University, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, icahn school of medicine at mount sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Three-dimensional lattice radiation therapy (3D-LRT) effectively achieves local tumor control with limited morbidity. Pencil beam scanning (PBS) proton therapy provides precise dose confor...
Authors: Xinxin Deng, Issam M. El Naqa, Jimm Grimm, Lijun Ma, Vitali Moiseenko, Timothy E. Schultheiss, Gopal Subedi, Wolfgang A. Tomé, Ellen D. Yorke, Albert van der Kogel
Affiliation: Montefiore Medical Center, Wellstar Kennestone Hospital Cancer Center, H. Lee Moffitt Cancer Center, Department of Human Oncology, University of Wisconsin–Madison, Department of Radiation Oncology, Wellstar Health System, Radiation Oncology, Keck School of Medicine of USC, Georgia Institute of Technology, University of California San Diego, City Of Hope National Medical Centre, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Reirradiation is increasingly utilized in clinical practice but dose-time recovery factors for human subjects remain uncertain. We constructed a reirradiation recovery model for spinal cord e...
Authors: Emi Ai Eastman, Vu Nguyen, Alexander W. Scott, Lucien Zang, Yifang (Jimmy) Zhou
Affiliation: Cedars-Sinai Medical Center
Abstract Preview: Purpose:
Three key features were developed to substantially improve a previously in-house developed CT protocol website: a structured backend for efficient protocol creation and edit; the ability t...
Authors: Shixiong Huang, Daming Li
Affiliation: The Affiliated Nanhua Hospital, University of South China, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University/Hunan Cancer Hospital
Abstract Preview: Purpose: To assess the feasibility of using target current pulse signals to evaluate the output dose of medical standing wave electronic linear accelerators.
Methods: The Target I signal of the acc...
Authors: Caridad Borras
Affiliation: Radiological Physics and Health Services
Abstract Preview: Purpose: The production, use, and disposal of radiopharmaceuticals must comply with regulations for drugs (medicines) and radiation. The relevant roles and requirements for medical physicists to be in...
Authors: Ming Dong, Carri K. Glide-Hurst, Joshua Pan, Nicholas R. Summerfield
Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Radiation dose to the cardiac nodes is more strongly associated with conduction disorders and arrythmias than whole heart (WH) metrics. However, node segmentation is challenging due to comple...
Authors: Bryan Bednarz, Laura Bennett, Abby E. Besemer, Tyler J Bradshaw, Steve Y Cho, John M. Floberg, Joseph Grudzinski, Elissa Khoudary, Michael J. Lawless
Affiliation: Department of Radiology, University of Wisconsin, University of Wisconsin-Madison Department of Medical Physics, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Voximetry, Inc, University of Pennsylvania, Department of Radiology, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: To assess the impact of using a standardized immobilization setup for multi-time-point SPECT/CT imaging on radiopharmaceutical therapy (RPT) dosimetry image registration.
Methods: Ten ...
Authors: Xiangli Cui, Wanli Huo, Jie Li, Lingling Liu, Tao Ma, Yuanyuan Wang
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Ion Medical Center, Hefei Cancer Hospital, Chinese Academy of Sciences, the Zhejiang-New Zealand Joint Vision-Based Intelligent Metrology Laboratory, College of Information Engineering, China Jiliang University
Abstract Preview: Purpose: In practice, treatment planning systems (TPS) of proton therapy require a CT calibration curve, which relates Hounsfield units (HU) to relative stopping power (RSP). Single-energy CT as a sta...
Authors: Jenghwa Chang, Chingyun Cheng, J Isabelle Choi, Muhammad Hamza, Minglei Kang, Tyler Kaulfers, Grant Lattery, Haibo Lin, Charles B. Simone, Xingyi Zhao
Affiliation: Peking University, Hofstra University Medical Physics Program, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Physics and Astronomy, Hofstra University, Physics Resident at Montefiore Einstein, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: In terms of high dose rate FLASH, the question remains on how to properly deliver treatment and what clinical sites are feasible to deliver such treatment. The novel Bragg peak (BP-FLASH) and...
Authors: Petr Bruza, Rafael Carballeira, Megan Clark, David J. Gladstone, Austin Sloop, Roman Vasyltsiv, Kevin Jacob Willy
Affiliation: Dartmouth College, Thayer School of Engineering, Dartmouth College
Abstract Preview: Purpose: Develop an optical dosimetry system to accomplish standard of care on-patient dosimetry and pretreatment quality assurance for ultra-high dose rate (UHDR) electron therapy ahead of human tria...
Authors: Ryan Burri, Nazanin Hoshyar, Jerry W. McCoy, Yulin Song, Huma Syed
Affiliation: Bay Pines VA Medical Center
Abstract Preview: Purpose: The study aimed to streamline traditionally manual, iterative, and time-consuming VMAT commissioning process. The goal was to identify an optimal set of MLC dosimetric parameters that minimiz...
Authors: John P. Aris, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Ann M. Chan, Chansoo Choi, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier
Affiliation: University of Florida
Abstract Preview: Purpose: In preclinical studies, minipigs serve as valuable experimental models for predicting absorbed doses due to their anatomical and physiological similarities to humans. However, minipig computa...