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Results for "multi sid": 52 found

3D Renal Microdosimetry: Evaluating Radiopharmaceuticals Using Histology-Based 3D Models

Authors: John P. Aris, Wesley E. Bolch, Madison Bushloper, Lauren E Ellis, Adam Grey Haneberg, Elizabeth Martin, Bonnie N. C. President, Andrew Robert Sforza, Alexander Zorrilla

Affiliation: Johns Hopkins University, Biomedical Engineering, University of Florida

Abstract Preview: Purpose: To develop six additional high-fidelity 3D models of kidney renal cortical labyrinth from H&E-stained histology slides to support radiation dosimetry in radiopharmaceutical therapies (RPTs).<...

A Multi-Institutional Survey of Current Therapeutic Medical Physics Residents’ Satisfaction and Interview Experience

Authors: Seifallah Emam, Gilberto Gonzalez, Anna E. Rodrigues

Affiliation: Duke University, University of Oklahoma Health Sciences Center

Abstract Preview: Purpose:
To survey current therapeutic medical physics residents on 1) the accuracy with which residency programs were represented during interviews, 2) factors that most strongly impacted resident...

A Novel Multi-Material Decomposition Algorithm for Improved Material Quantification Using Dual-Energy CT

Authors: Dale Black, David Clymer, Huanjun Ding, Hamidreza Khodajou Chokami, Sabee Molloi, Christine Vy Nguyen, Tim Sananikone, Alireza Shojazadeh, Randy Wang

Affiliation: Department of Radiological Sciences, University of California, University of California, Department of Radiological Sciences, University of California, Irvine, Department of Radiological Sciences, University of California, Irvine

Abstract Preview: Purpose: We present a novel multi-material decomposition (MMD) algorithm for accurate quantification of material concentration in reconstructed dual-energy CT images. This method addresses limitations...

A Two-Layer, Two-Task Prediction Model Based on 3D Imaging and Residual Networks for Mid-Chemoradiation Tumor Response Prediction on FDG PET for La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jing Sun, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Xiaojing Zhu

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Shanghai University of Electric Power, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Accurate prediction of patient response to radiotherapy plays a crucial role in monitoring disease progression and assessing treatment efficacy, enabling clinicians to develop personalized th...

AI Auto-Contouring for CT-Based High-Dose-Rate Interstitial Brachytherapy of Cervical Cancer: Implications for Organ-at-Risk (OAR) Contouring and Dosimetric Analysis

Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl

Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center

Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...

An Automated Tool for the Categorization of a Clinical Database By Anatomic Region for Big Data Applications

Authors: Yasin Abdulkadir, Justin Hink, James M. Lamb, Jack Neylon

Affiliation: Department of Radiation Oncology, University of California, Los Angeles

Abstract Preview: Purpose: Curation remains a significant barrier to the use of ‘big data’ radiotherapy planning databases of 100,000 patients or more. Anatomic site of treatment is an important stratification for almo...

An International Multi-Institutional Espresso Study of Developing the Specialized-Equipment-Free Remote Audit for Single-Isocenter Multi-Target Stereotactic Radiosurgery

Authors: Juan-Francisco Calvo-Ortega, Andrew Cousins, Ashley Cullen, Andrew Dipulia, Peter B. Greer, Seng Boh Gary Lim, Shih-Chi Lin, D. Michael Lovelock, Conor McGarry, Victoria Robinson, Cameron Stanton, Baozhou Sun, Ching-Ling Teng, Gemma Warner, Benjamin J. Zwan

Affiliation: Northern Ireland Cancer Centre, Baylor College of Medicine, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Christchurch Hospital, Northwell, Central Coast Cancer Centre, Calvary Mater Hospital, Hospital Quironsalud Barcelona, Icahn School of Medicine at Mount Sinai, Chris O'Brien Lifehouse, University of Newcastle

Abstract Preview: Purpose: This multi-institution Electronic Silicon-based Remote Survey of Small-field Output (ESPRESSO) study aims to develop the remote audit process to evaluate the safety of single-isocenter multi-...

Artificial Intelligence-Powered Conventional Energy Integrating Detector-Based Coronary CT Angiography: Learning High-Resolution and Multi-Energy Imaging from Photon-Counting Detector CT

Authors: Shaojie Chang, Thomas A. Foley, Hao Gong, Emily Koons, Shuai Leng, Cynthia H. McCollough, Eric E. Williamson

Affiliation: Mayo Clinic

Abstract Preview: Purpose: To enhance coronary CT angiography (cCTA) capabilities on conventional energy integrating detector CT (EID-CT) using artificial intelligence (AI). The AI framework incorporates high-resolutio...

Assessment of the Impact of CT Respiratory Motion on PET SUV Quantification through Virtual Imaging

Authors: Ehsan Abadi, Darrin Byrd, Paul E. Kinahan, Katie Marie Olivas, Ehsan Samei

Affiliation: Duke University, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System, University of Washington

Abstract Preview: Purpose: To evaluate the impact of respiratory motion during CT acquisitions on PET image quantification using an integrated PET-CT simulation pipeline.
Methods: A validated CT simulator (DukeSim) ...

Brachyplancheck: An Independent Monte Carlo Dose Calculation Tool for Brachytherapy Using Egs_Brachy

Authors: Amy Tien Yee Chang, Chi Wai Cheung, Tin Lok Chiu, Chen-Yu Huang, Chi Wa Kong, Pei-Xiong Li, Pak Hang Nam, Bin Yang, Siu Ki Yu

Affiliation: Comprehensive Oncology Centre, Hong Kong Sanatorium and Hospital, Medical Physics Department, Hong Kong Sanatorium and Hospital

Abstract Preview: Purpose: This study introduces BrachyPlanCheck, an independent Monte Carlo (MC)-based dose calculation tool for 192Ir brachytherapy retrospective study or algorithm commissioning.
Methods: BrachyPl...

Brain Tumor Segmentation from Multi-Parametric MRI with Integrated Evidential Uncertainty Estimation

Authors: Sahaja Acharya, Matthew Ladra, Junghoon Lee, Lina Mekki

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University

Abstract Preview: Purpose: Multi-parametric MRI (mpMRI) is widely used for deep learning (DL)-based automatic segmentation of brain tumors. While multi-contrast images concatenated as channels are typically input to ne...

Characterization of HCC Tumor Response in 90Y-Radioembolization Clinical Trial RAPY90D Using Prospective Voxel Dosimetry

Authors: E Courtney Henry, Srinivas Cheenu Kappadath, Armeen Mahvash

Affiliation: UT MD Anderson Cancer Center

Abstract Preview: Purpose:
Characterization of hepatocellular carcinoma (HCC) tumor responses for single-arm single-center prospective 90Y-radioembolization clinical trial (n=40) that used patient-specific voxel-dos...

Commissioning of an AI-Assisted Tool for Enhancing Post-Radiosurgery Follow-up in Multiple Brain Metastases Patients

Authors: Rex Carden, Carlos E. Cardenas, Ho-hsin Rita Chang, John B Fiveash, Heinzman A. Katherine, Yogesh Kumar, Gaurav Nitin Rathi, Richard A. Popple, Kayla Lewis Steed

Affiliation: University of Alabama at Birmingham

Abstract Preview: Purpose: Brain metastases (BMs) often require multiple radiotherapy (RT) courses as new lesions appear. Comparing follow-up imaging with prior RT plans is time-intensive. We developed an AI tool that ...

Comparitive Case Analysis of Maa Mapping and Angiographic Iodinated Contrast for Y-90 SIRT Treatment Planning

Authors: Shengwen Deng, Sven L. Gallo, Robert S. Jones, David W. Jordan, Arashdeep Kaur, Aishwarya M. Kulkarni, Quibai Li, William R.M. Pedersen

Affiliation: Department of Radiology, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center, Department of Radiology, Radiation Safety, University Hospitals Cleveland Medical Center; School of Medicine, Case Western Reserve University; Department of Radiology, Louis Stokes Cleveland VA Medical Center

Abstract Preview: Purpose:
Y-90 (Yttrium) SIRT radioembolization takes advantage of delivering localized radiation to the liver. Pre-treatment dosimetry is highly dependent on accurate MAA mapping, which may have an...

Comprehensive Analysis of Plan Modulation in SRS/SBRT Plans: A Single Institution Study of 461 Cases

Authors: Yunfeng Cui, Will Giles, Xinyi Li, Ke Lu, Jennifer C. O'Daniel, Anna E. Rodrigues, Chunhao Wang, Lana Wang, Yibo Xie, Sua Yoo, Jingtong Zhao

Affiliation: Duke University, Duke University Medical Center

Abstract Preview: Purpose:
To establish quantitative measurement of plan modulation for SRS/SBRT treated with Volumetric Modulated Arc Therapy (VMAT) on C-arm LINACs.
Methods:
A total of 461 plans were analyze...

Cross Characterization of a 3D Gamma Camera and Ring Brachytherapy Applicator

Authors: Zachary R. Grelewicz, Kevin C. Jones, Yixiang Liao, Andrew Ogilvy, Julius V. Turian

Affiliation: Rush University Medical Center

Abstract Preview: Purpose: To demonstrate the accuracy and QA application of a time-resolved 3D gamma camera, we measured the path traversed by the Ir-192 High-Dose-Rate (HDR) brachytherapy source passing through a rin...

Decreasing the Dependence of CT Number on the Position in the Field-of-View Using Photon Counting Detector CT

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: The dependence of CT number on position in the field-of-view (FOV) imposes challenges in radiotherapy treatment planning. This study aims to decrease this dependence using photon counting det...

Deep Learning Based Automatic Cerebrovascular Segmentation in Multi-Center TOF-MRA Datasets

Authors: Gayoung Kim, Junghoon Lee

Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University

Abstract Preview: Purpose: 3D time-of-flight magnetic resonance angiography (TOF-MRA) is widely used for visualizing cerebrovascular structures. Accurate segmentation of cerebrovascular structures is critical for relia...

Demystifying Magnetic Resonance Imaging: Targeted Educational Initiatives for Medical Physicists in TĂŒrkiye and Preclinical Medical Students in the United States

Authors: Samuel A. Einstein, Jesutofunmi Fajemisin, Evren O. Göksel, Görkem O. GĂŒngör, Marthony Robins, Travis C. Salzillo, Charles R. Thomas, Turgay Toksay, Joseph Weygand, Yue Yan

Affiliation: Acibadem MAA University, Department of Radiation Oncology and Applied Science, Dartmouth Health, Dartmouth College, Moffitt Cancer Center, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Penn State College of Medicine, Bursa Ali Osman Sönmez Oncology Hospital

Abstract Preview: Purpose: Magnetic resonance imaging (MRI) is an indispensable clinical tool, offering unparalleled soft tissue contrast critical for diagnosing and managing a wide range of conditions. However, its co...

Denoising Diffusion-Weighted Images of Rectal Cancer Acquired on a 0.35 T Magnetic Resonance Imaging-Guided Linear Accelerator Using Singular Value Decomposition

Authors: Jacqueline M. Andreozzi, Tess Armstrong, Shiva Bhandari, John M Bryant, Jessica M Frakes, David J. Gladstone, Sarah E Hoffe, Kujtim Latifi, Arash Naghavi, Steven Nichols, Ibrahim M. Oraiqat, Russell Palm, Gage H. Redler, Stephen A Rosenberg, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Thayer School of Engineering, Dartmouth College, Department of Radiation Oncology, Ohio State University, Moffitt Cancer Center, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose: The MR-linac provides unique opportunities for integrating advanced imaging into radiotherapy workflows, but the lower sensitivity of systems like the 0.35T model can pose challenges for diff...

Dependency of CT Number on Position in the Field-of-View for Single- and Multi-Energy Images Acquired with Energy-Integrating-Detector and Photon-Counting-Detector CT Scanners

Authors: Yanle Hu, Shuai Leng, Cynthia H. McCollough, Maryam Sadeghian, Joe Swicklik

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To assess the dependency of CT numbers on position in the field-of-view (FOV) using single-energy (SE) and dual-energy (DE) images and energy-integrating detector (EID) and photon-counting de...

Development of a Knowledge-Based Planning Model for Optimal Trade-Off Guidance in Locally Advanced Non-Small Cell Lung Cancer

Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai

Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...

Developments of a Low-Cost Multi-Target Winston-Lutz Phantom and Software for SRS Linac Machines

Authors: Nellie Brovold, Wenbo Gu, Huan Amanda Liu, Lin Ma

Affiliation: University of Pennsylvania, Mayo Clinic

Abstract Preview: Purpose: To develop a low-cost comprehensive QA phantom and software for single-iso multi-target SRS Linac machines. This phantom can perform 1) Winston-Lutz QA test for on-axis and off-axis targets, ...

Dosimetric Assessment of Multicriteria Optimization for Accelerated Partial Breast Irradiation (APBI)

Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...

Effects of Plan Optimization Techniques on Relative Biological Effective Dose in a Thin Intracranial Target Volume

Authors: Sean P. Boyer, Shae Gans, Mingcheng Gao, Draik B. Hecksel, Mark Pankuch

Affiliation: Northwestern Medicine Proton Center, Northwestern Medicine Chicago Proton Center

Abstract Preview: Purpose: Protons deposit a large portion of their energy at the end of their range in a region known as the Bragg peak, which may increase the relative biological effective (RBE) dose in this region. ...

Enhanced Pelvic Organ Segmentation Using LLM-Driven Prompts for Prostate Cancer Low-Dose-Rate Brachytherapy

Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang

Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University

Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...

Establishing Tumor Size-Dependent Contrast Requirements for Multi-Target Biology-Guided Radiation Therapy (BgRT)

Authors: Muhammad Ramish Ashraf, Girish Bal, Daniel Pham, Murat Surucu

Affiliation: RefleXion Medical, Department of Radiation Oncology, Stanford University School of Medicine, Stanford University

Abstract Preview: Purpose: To determine minimum target size and FDG contrast thresholds for reliable Biology-guided Radiation Therapy (BgRT) delivery using a systematic phantom study.
Methods: A custom 3D-printed ph...

Evaluation of Hybrid Dynamic Conformal Arc Planning for SRS and SBRT Treatment

Authors: Pat Esposito, Ashley Klein, Carmine Verna, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: To evaluate dosimetric parameters and treatment delivery efficiency between volumetric modulated arc therapy (VMAT) and hybrid dynamic conformal arc (HDCA) on SRS and SBRT planning through st...

Evaluation of the Dosimetric Characteristics of Multi-Layers of Brass Mesh Bolus for Electron Treatment

Authors: Yunzhi Ma, Ling Zhuang

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: Multiple layers of brass mesh bolus (RPD, Inc., Albertville, MN) may be needed to provide better body conformity and sufficient dose build up on patient surface during electron treatment. Thi...

Gaze Angle Selection in Proton Therapy for Ocular Tumors with Machine Learning

Authors: Ling Chen, Alexei V. Trofimov, Yi Wang, Dufan Wu

Affiliation: Massachusetts General Hospital, MGH

Abstract Preview: Purpose:
Selecting gaze angles of the eye is an important part of set-up of proton therapy for ocular tumors, ensuring that the treatment beam could irradiate the tumor while maximally sparing impo...

High-Temporal Dynamic CBCT Imaging Via Gaussian Neural Representation

Authors: Weixing Cai, Laura I. Cervino, Yabo Fu, Licheng Kuo, Tianfang Li, Xiang Li, Jean M. Moran, Huiqiao Xie, Hao Zhang

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center

Abstract Preview: Purpose: This study introduces a novel spatiotemporal Gaussian neural representation framework to reconstruct high-temporal dynamic CBCT images from 1-minute acquisition, preserving motion dynamics an...

Hydrated Electron Yield Under Electron Irradiation at Ultra-High Dose Rates with Varying Physical Beam Parameters

Authors: Xu Cao, Wesley S. Culberson, Aubrey Parks, Brian W Pogue, Matthew Reed, William Scott Thomas

Affiliation: University of Wisconsin: Madison, Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin-Madison, University of Wisconsin - Madison, UW-Madison

Abstract Preview: Purpose: Under Ultra-High Dose Rate (UHDR) irradiation, radical-radical interactions are likely enhanced due higher density production in time and space and this alters the cascade of reactions that s...

Impact of Six Degrees of Freedom Intrafraction Motion on Target Coverage for Single-Isocenter Multi-Target Stereotactic Radiosurgery

Authors: Anupama Chundury, Hyejoo Kang, John C. Roeske, Iris A. Rusu

Affiliation: Loyola University Medical Center, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose: To quantify the dosimetric impact of six degrees of freedom (6DoF) intrafractional errors on gross tumor volume (GTV) and planning target volumes (PTV) for single-isocenter multi-target stere...

Improvements of Lateral Penumbra at Various Depth Regions in Scanned Proton Treatment System with a Multi-Leaf Collimator: Dose Verifications and Plan Comparisons

Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka

Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University

Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...

Investigation of Metallic Artefact Reduction Capabilities of Hypersight Enabled Platforms

Authors: Harald Keller, Iymad Mansour, Jeff D. Winter

Affiliation: Princess Margaret Cancer Centre

Abstract Preview: Purpose: The growing number of adaptive therapy applications is motivating image segmentation and direct dose calculation on CBCT. The purpose of this investigation is to evaluate the recently release...

Lu-PSMA-Dose, a French Retrospective Multicentric Dosimetry Study of 177Lu-PSMA Treatments for Metastatic Castration-Resistant Prostate Cancer

Authors: NadÚge Anizan, Jean-Noël Badel, Thomas Baudier, David Broggio, Désirée Deandreis, Ludovic Ferrer, Didier Franck, Camilo Garcia, Jean Gasteuil, Anne-Laure Giraudet, Olivier Humbert, Laetitia Imbert, Malick Koulibaly, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard, Caroline Rousseau, Guido Rovera, David Sarrut, Paul Schwartz, Nicolas Varmenot

Affiliation: Institut de CancĂ©rologie de l’Ouest, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de Physique MĂ©dicale, Institut BergoniĂ©, Service de Physique MĂ©dicale, CHRU de Nancy Brabois, Service de MĂ©decine NuclĂ©aire, Centre de lutte contre le cancer LĂ©on BĂ©rard, UniversitĂ© de Lyon, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, UniversitĂ© Nice CĂŽte d’Azur, Centre Antoine Lacassagne, Service de MĂ©decine NuclĂ©aire, Gustave Roussy, Service de MĂ©decine NuclĂ©aire, Institut de CancĂ©rologie de l’Ouest, Service de Physique MĂ©dicale, Service de MĂ©decine NuclĂ©aire, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, AutoritĂ© de SĂ»retĂ© NuclĂ©aire et de Radioprotection (ASNR), PSE-SANTE/SDOS, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSA‑Lyon, CREATIS CNRS UMR 5220; INSERM U 1044; UniversitĂ© de Lyon; INSA‑Lyon; Centre de lutte contre le cancer LĂ©on BĂ©rard, Institut BergoniĂ©, Service de MĂ©decine NuclĂ©aire

Abstract Preview: Purpose: The main objective of the Lu-PSMA-Dose study, sponsored by ASNR, is to estimate retrospectively the individual absorbed dose delivered to patients treated with 177Lu-PSMA for metastatic castr...

Lung-Equivalent Compressible Material As Core Component for a Miniaturized Breathing Phantom Prototype

Authors: Silvia Calusi, Lucia Cavigli, Alberto Dalla Mora, Laura Di Sieno, Giacomo Insero, Riccardo Lisci, Livia Marrazzo, Cosimo Nardi, Stefania Pallotta, Andrea Profili, Fulvio Ratto, Giovanni Romano, Michaela Servi, Immacolata Vanore, Yary Volpe

Affiliation: Italian National Research Council IFAC-CNR, Institute of Applied Physics, Department of Physics, Politecnico di Milano, Department of Agricultural Food and Forestry System, University of Florence, Medical Physics Unit, Azienda Ospedaliero-Universitaria Careggi, Department of Industrial Engineering, University of Florence, Department of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence

Abstract Preview: Purpose: To develop a multi-purpose lung phantom prototype to replicate respiratory dynamics and morphological features observed in clinical radiological (CT and MR) imaging of lung parenchyma.
Met...

Modality-Agnostic Image Cascade (MAGIC) for Multi-Modality Cardiac Substructure Segmentation

Authors: Ming Dong, Carri K. Glide-Hurst, Qisheng He, Anudeep Kumar, Alex Singleton Kuo, Joshua Pan, Chase Ruff, Nicholas R. Summerfield

Affiliation: Department of Computer Science, Wayne State University, Departments of Human Oncology and Medical Physics, University of Wisconsin-Madison, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Recent evidence highlights the importance of incorporating cardiac substructures (CS) into treatment planning for thoracic cancers, however current segmentation methods are limited to a singl...

Modified Dehazenet for Scatter Correction in Triggered Imaging: Enhancing Visibility and Alignment Precision for Radiation Therapy

Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang

Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University

Abstract Preview: Purpose: Scatter in X-ray imaging degrades image quality, hindering the visibility of critical anatomical features and complicating patient alignment in radiation therapy. This study aims to improve s...

Muilt-Instance Learning Model with 2D and 3D Features Representation and Transformer-Based Prediction for FDG PET Tumor Chemoradiation Response of La-NSCLC

Authors: Stephen R. Bowen, Chunyan Duan, Daniel S. Hippe, Qiantuo Liu, Jiajie Wang, Shouyi Wang, Faisal Yaseen, Han Zhou

Affiliation: Tongji University, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Fred Hutchinson Cancer Center, University of Texas at Arlington

Abstract Preview: Purpose: Predicting the effects of the spatial-temporal tumor response to chemoradiation can assist in adjusting radiation dose and support clinical decision-making in radiotherapy. A multi-instance l...

Multi-Center Diffusion-Weighted MRI Validation for 0.35T MR-Linac: A Repeatability and Reproducibility Study

Authors: Tess Armstrong, Nema Bassiri, Alonso N. Gutierrez, Michael Kasper, Natalia Lutsik, Eric Mellon, Kathryn E. Mittauer, Siamak P. Nejad-Davarani, Shyam Pokharel, Suresh Rana, Hui Wang, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, Miami Cancer Institute, Baptist Health South Florida, ViewRay, Inc., Miami Cancer Institute, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida, Department of Radiation Oncology, University of Miami

Abstract Preview: Purpose: Radiation treatments on the MR-linac (MRL) enable daily acquisition of anatomical and physiological images for adaptive treatment planning. The apparent diffusion coefficient (ADC) estimated ...

Multi-Institutional Analysis of CT Dose Index Variability and Radiomics Features

Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong

Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati

Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...

Multi-Institutional Evaluation of Radiographic Automatic Exposure Control Performance Testing: Methodology, Outcomes, and Failure Rates

Authors: Caroline Cheney, Nicole M. Lafata, Zaiyang Long, Dustin W. Lynch, Erin B. Macdonald, Andy Madore, Douglas E. Pfeiffer, Colin Schaeffer, Alexander W. Scott

Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, UVA Health, Duke University Health System, Mayo Clinic, Henry Ford Health, Boulder Community Health, Varian, Cedars-Sinai Medical Center

Abstract Preview: Purpose: This work evaluates the significance of performing established radiography automatic exposure control (AEC) tests by comparing testing methodology, outcomes, and failure rates across multiple...

Multi-Sid Optimization for 4 Pi Robotic Radiotherapy

Authors: Qihui Lyu, Dan Ruan, Ke Sheng, Jingjie Yu

Affiliation: Department of Radiation Oncology, University of California, Los Angeles, University of California, San Francisco, Department of Radiation Oncology, University of California, San Francisco

Abstract Preview: Purpose: The robotic arm radiotherapy platform enables flexible delivery of non-coplanar and non-isocentric radiotherapy with variable Source-to-Isocenter Distances (SIDs). However, the high degrees o...

Proton Therapy Treatment Planning for Thoracic Cancer: A Comparative Analysis of Single and Multi-Field Plans

Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu

Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection

Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...

Reducing Variable Rbe in Oars for HN, Breast, and Prostate Proton Therapy Using a Scripted Spot-Delete Technique

Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey

Affiliation: Thompson Proton Center

Abstract Preview: Purpose: Linear energy transfer (LET) and variable relative biological effectiveness (RBE) evaluation are important steps in the future of proton therapy, moving beyond RBE=1.1 for all treatment plann...

Region-Specific Structure-Function Coupling Alterations in Parkinson’s Disease: Insights from Multi-Modal MRI

Authors: Yifei Hao, Ting Huang, Wenxuan Li, Xiang Li, Manju Liu, Rong Liu, Tao Peng, Yulu Wu, Fang-Fang Yin, Lei Zhang, Yaogong Zhang, Jiangtao Zhu

Affiliation: Duke University, Department of Radiology, The Second Affiliated Hospital of Soochow University, School of Future Science and Engineering, Soochow University, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study investigates the alterations in structure-function coupling (SC-FC) networks in Parkinson’s disease (PD) patients, focusing on region-specific disruptions and compensatory mechanis...

Robust Evaluation of Rotational Uncertainties on Single-Isocenter Multi-Target Stereotactic Radiosurgery Hyperarc Treatment

Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...

Streamlined Stereotactic Radiosurgery (SRS) Commissioning Experience with a 6FFF Beam for an Elekta Versa: A Clinical Overview for Increased Precision.

Authors: Asma Amjad, Slade J. Klawikowski, Natalya V. Morrow, Haidy G. Nasief, Eric S. Paulson, An Tai, Hualiang Zhong

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Accurate and precise linac-based SRS commissioning can be very challenging. Thus, it is important to increase the confidence in the measurement at each step prior to end-to-end testing. The p...

Tackling the Challenge of Multi-Target Metastases Treatment: Evaluation of Ethos Treatment Planning System

Authors: Avery Antes, Bulent Aydogan, Rama Chicfeh, Erik Pearson, Neslihan Sarigul

Affiliation: The University Of Chicago, The University of Chicago

Abstract Preview: Purpose: This study evaluates the performance of the Ethos Treatment Planning System (TPS) in managing oligometastatic cancer patients previously treated using multiple isocenter plans.
Methods: Th...

Targeted Multi-Criteria Optimization for Rapid Improvement of Organ-at-Risk Dose in the Setting of Prostate Stereotactic Body Radiation Therapy

Authors: Alyssa Gadsby, William J. Godwin, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan

Affiliation: Medical University of South Carolina

Abstract Preview: Purpose: To utilize multi-criteria optimization (MCO) in a targeted fashion to quickly and easily improve dose to the rectum when treating the prostate with stereotactic body radiation therapy (SBRT)....

Tumor Density on Time-Weighted Mid-Position Images for Thoracic Tumors

Authors: Katrinus Keijnemans, Eric S. Paulson, An Tai

Affiliation: Department of Radiotherapy, University Medical Center Utrecht, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Time-weighted mid-position images (MidPs), derived from four-dimensional computed tomography (4DCT) via deformable image registration (DIR), are frequently selected for treatment planning due...