Authors: Brett Bocian, Nesrin Dogan, John C. Ford, Alan Pollack, Ryder Marshall Schmidt, Junwei Shi, Jorge D Vega
Affiliation: University of Miami, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose: X-ray fluorescence computed tomography (XFCT) is an emerging molecular imaging modality gaining attention in cancer theranostics with high-Z metal nanoparticles (MNPs). While XFCT has been de...
Authors: Huixiao Chen, Ethan Hartowicz, Lichung Ku, Tim Perez, Ray Yang
Affiliation: Salem Health, RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: To characterize MV-kV isocenter offset on a novel ring gantry radiotherapy system where the Linac, PET, kV-CT, and MV imaging subsystems rotate together at native operating speed of 60RPM.
Authors: Izabella L. Barreto, Benjamin Taylor Heggie, Stephanie M. Leon
Affiliation: University of Florida College of Medicine, University of Florida
Abstract Preview: Purpose: 3D printing has the potential for producing materials useful for the imaging field. This work aims to identify absorption (attenuation coefficient) and material properties (effective atomic n...
Authors: Aman Anand, Jonathan B. Ashman, Martin Bues, Brady S. Laughlin, Lisa McGee, Justin Pettit, Fan Yang, Libing Zhu
Affiliation: Department of Radiation Oncology Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose: Proton therapy (PT) offers significant clinical and economic benefits across various cancers, whereas it also has faced skepticism due to its historically high costs and perceived overuse in ...
Authors: Craig K Abbey, John M. Boone, Richard E. Colbeth, Andrew M. Hernandez, Vance Robinson, Paul Schwoebel, Jeffrey H. Siewerdsen, Alejandro Sisniega, Wojciech B. Zbijewski, Huanyi Zhou
Affiliation: UC Santa Barbara, University of California, UT MD Anderson Cancer Center, Johns Hopkins University, University of New Mexico Albuquerque, UC Davis Health, Varex Imaging Corporation
Abstract Preview: Purpose: A new CT configuration utilizing a multiple X-ray-source array (MXA) is under development to mitigate cone-beam (CB) artifacts in single-rotation wide coverage imaging. We investigate the sam...
Authors: Jing-Tzyh Alan Chiang, Andrew Karellas, Thomas C Larsen, Hsin Wu Tseng, Srinivasan Vedantham
Affiliation: Department of Biomedical Engineering, The University of Arizona, Department of Medical Imaging, The University of Arizona
Abstract Preview: Purpose: To investigate the performance of dedicated breast computed tomography (BCT) for the the tasks of detection of soft tissue lesions and microcalcifications using cascaded systems analysis. The...
Authors: Soon N. Huh, Perry B. Johnson, Jiyeon Park, Ryan Stevens
Affiliation: University of Florida Health Proton Therapy Institute, UF Health Proton Therapy Institute, UFHPTI
Abstract Preview: Purpose:
Cone-beam computed tomography (CBCT) doses shall be limited for pediatric patients in clinical settings. Device called Filtimator (filter+collimator) was custom designed to reduce setup CB...
Authors: Alexander Bookbinder, Matthew Tivnan, Xiangyi Wu, Wei Zhao
Affiliation: Stony Brook Medicine, Massachusetts General Hospital
Abstract Preview: Purpose: To investigate and benchmark a system-adaptive diffusion-based digital breast tomosynthesis (DBT) denoising model for a direct-indirect dual-layer flat panel detector (DI-DLFPD) with a k-edge...
Authors: Mohammed Alzaabi, Owen Thomas Dillon, Julia Johnson, Andrew Kanawati, Tess Reynolds, Ann Yan
Affiliation: Westmead Hospital, Image X Institute, Faculty of Medicine and Health, The University of Sydney, Khalifa University
Abstract Preview: Purpose: To develop a physiological carotid artery phantom and Bayesian geometric calibration method to examine the feasibility of extended field-of-view interventional CBCT artery imaging using a mul...
Authors: Hyo-Min Cho, Changwoo Lee
Affiliation: Korea Research Institute of Standards and Science
Abstract Preview: Purpose: We develop sphere phantoms to assess spatial resolution of computed tomography (CT) systems and validate its usability using table-top X-ray experiment systems.
Methods: We manufactured sp...
Authors: Ruirui Dong, Gernot Echner, Peter Haering, Clarence King, Carlos Murillo, Gavin Poludniowski, Nicholas Sammut, Joao Seco, Steffen Seeber, Maria Francesca Spadea, Elpida Theodoridou
Affiliation: KIT, Department of Physics and Astronomy, Heidelberg University, Karolinska Institutet, DKFZ, University of Malta
Abstract Preview: Purpose:
The goal is to develop the first benchtop X-ray FLASH system based on a conventional small animal irradiator. The small animal irradiator will be modeled using a Monte Carlo toolkit for bo...
Authors: David Ayala Alvarez, Facundo Ballester, Luc Beaulieu, Francisco Berumen-Murillo, Jean-Simon Cote, Ernesto Mainegra-Hing, Iymad Mansour, Gaël Ndoutoume-Paquet, Jan P. Seuntjens, Rowan M. Thomson, Christian Valdes, Javier Vijande, Peter G. Watson
Affiliation: Département de physique, de génie physique et d'optique, Université Laval, Princess Margaret Cancer Centre & University of Toronto, McGill University, Department of Physics and Medical Physics Unit, McGill University, IFIC-UV, University of Valencia, National Research Council Canada, Carleton University, 5Service de Physique Médicale et de Radioprotection, Centre Intégré de Cancérologie, CHU de Québec- Université Laval et Centre de recherche du CHU de Québec, Nuclear Medicine Department, Hospital Regional de Antofagasta, Université Laval, Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University
Abstract Preview: Purpose: Low-energy X-ray beams used in electronic brachytherapy (eBT) pose unique dosimetric challenges due to high depth-dose gradients, material-dependent detector responses, and the absence of sta...
Authors: Jongduk Baek, Jooho Lee, Adam S. Wang
Affiliation: Stanford University, Yonsei University
Abstract Preview: Purpose: Optimizing the balance between radiation dose and image quality in computed tomography (CT) is important for minimizing patient X-ray exposure while maintaining diagnostic accuracy. While rad...
Authors: Chen-Ju Feng, Shih-Ming Hsu, Chin-Hsiung Lin, Shih-Yong Luo, Shao-Chun Tseng, Chin-Hui Wu, Ya-Ru Yang
Affiliation: National Yang Ming Chiao Tung University, Koo Foundation Sun Yat-Sen Cancer Center, Tzu-Chi University, NanoRay Biotech Co., Ltd
Abstract Preview: Purpose: The range of auger electrons in water is 2~500 nm, and its linear energy transfer reaches 26 keV/μm. This study investigated the feasibility of the auger electron radiation therapy.
Method...
Authors: Ciprian N. Ionita, Parisa Naghdi, Ahmad Rahmatpour
Affiliation: University at Buffalo, SUNY: University at Buffalo
Abstract Preview: Purpose: Quantitative angiography (QA) evaluates neurovascular hemodynamics, but is affected by X-ray parameters, vessel foreshortening, and imaging chain factors like detector efficiency, pixel size,...
Authors: Matthew R. Hoerner, Maryam Naseri, Mena Shenouda
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose:
Historically film has been the gold standard receptor for measurements of x-ray tube focal spot size. Flat Panel Digital Radiography Detectors (FPDRDs) have lower spatial resolution compar...
Authors: John M. Boone, Andrew M. Hernandez, Paul E. Kinahan, Michael F. McNitt-Gray, Jeffrey H. Siewerdsen, Ali Uneri
Affiliation: University of California, Johns Hopkins Univ, UT MD Anderson Cancer Center, David Geffen School of Medicine at UCLA, University of Washington, UC Davis Health
Abstract Preview: Purpose: Measuring image quality (IQ) in large clinical databases, such as the Medical Imaging and Data Resource Center (MIDRC), is challenging due to the inherent complexity of image content and the ...
Authors: Emily Y. Hirata, Xiaoyu Sherry Liu, Evan Porter, Manju Sharma
Affiliation: University of California San Francisco, University of California, San Francisco, University of California
Abstract Preview: Purpose: Introduced in 2018, the Varian Halcyon platform has increased in popularity due to its reduced cost, user-friendly design, and operational efficiency. As this platform ages, major repairs, in...
Authors: Vibha Chaswal, Stephen D. Davis, Alonso N. Gutierrez, Noah S. Kalman, Yongsook C. Lee, William Romaguera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose: To report machine performance of our superficial radiation therapy unit (SRT-100 Vision, Sensus Healthcare, Boca Raton, FL) for the first three years after commissioning of the unit.
Metho...
Authors: Matthew R. Hoerner, Allison Shields
Affiliation: Yale University School of Medicine, Yale University
Abstract Preview: Purpose: To investigate the quality and clinical utility of chest x-rays synthesized from CT scans (sCXR).
Methods: Five helical chest CT exams were chosen for evaluation: this cohort represented a...
Authors: Dirk A Bartkoski, Leonard Che Fru, Benjamin Abraham Insley, Michael Kleckner, Dongyeon Lee, Reza Reiazi, Mohammad Reza Salehpour, Aviad Schori, Ramesh C. Tailor
Affiliation: Empyrean Medical Systems, The University of Texas MD Anderson Cancer Center, Convergent-RnR, The University of Texas, MD Anderson, Houston TX
Abstract Preview: Purpose: A Geant4-based model was created for a G4BraggReflection process to simulate radiation transport within a novel radiotherapy system developed by Convergent Radiotherapy and Radiosurgery (CRnR...
Authors: Hyosung Cho, Dae Yup Han, Duhee Jeon, Jiwon Park, Hyesun Yang
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine, Yonsei University
Abstract Preview: Purpose: Scatter in X-ray imaging degrades image quality, hindering the visibility of critical anatomical features and complicating patient alignment in radiation therapy. This study aims to improve s...
Authors: Corentin Desport, Dominique Iacchetti, Nicolas Kien, Ramiro Moreno, Melodie Munier, Séléna Pondard
Affiliation: Fibermetrix, Alara Expertise, Alara Group
Abstract Preview: Purpose: To evaluate the efficiency of organ-based tube current modulation (OBTCM) in thoracic and abdominopelvic Computed Tomography (CT) for different radiology departments and manufacturers. This s...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: The purpose of this work is to describe the design and development of a newly developed upright-geometry dedicated breast CT system and to quantitatively and qualitatively evaluate its imagin...
Authors: Njood Alsaihati, Francesco Ria, Ehsan Samei, Justin B. Solomon, Martina Talarico, Jered Wells
Affiliation: Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose: Radiation dose and associated risk in X-ray imaging is principally informed by patient size, further used in Computed Tomography (CT) to achieve prescribed image quality levels through tube c...
Authors: Hadley Anna DeBrosse, Kevin J. Little
Affiliation: The Ohio State University
Abstract Preview: Purpose: This work examines the consistency and pattern of spatial resolution degradation in weekly quality control (QC) testing prior to CT tube failure and replacement and investigates potential cor...
Authors: Wesley S. Culberson, Ryan Gardner, John Thomas Stasko
Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, University of Wisconsin
Abstract Preview: Purpose: X-ray tube voltage is a critical parameter in influencing an X-ray tube’s beam quality. The endpoint tube potential, the potential difference between the X-ray tube’s cathode and anode, is pa...
Authors: Ehsan Abadi, Zakaria Aboulbanine, Nicholas D Felice, David Fenwick, Anuj J. Kapadia, Cindy Marie McCabe, Jayasai Ram Rajagopal, Ehsan Samei
Affiliation: Duke University, Oak Ridge National Laboratory, Center for Virtual Imaging Trials, Duke University, Clinical Imaging Physics Group, Department of Radiology, Duke University Health System
Abstract Preview: Purpose:
Virtual imaging trials (VITs) offer a computational alternative to clinical imaging trials leveraging virtual patients, scanners, and interpreters to assess imaging questions. To provide m...
Authors: Stephen Araujo, Jing-Tzyh Alan Chiang, Cynthia E. Davis, Eri Haneda, Andrew Karellas, Thomas C Larsen, William Ross, Hsin Wu Tseng, Srinivasan Vedantham, Pengwei Wu
Affiliation: Department of Biomedical Engineering, The University of Arizona, GE Aerospace Research, Department of Medical Imaging, The University of Arizona, GE HealthCare Technology & Innovation Center
Abstract Preview: Purpose: To determine the system parameters and technique factors for image acquisition needed so that the mean glandular dose (MGD) of approximately 4.5 mGy is not exceeded for a recently developed, ...