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Results for "toxicity maintaining": 10 found

Advancing Post-Radiotherapy Toxicity Extraction: A Novel Privacy-Preserving, Parameter-Efficient Language Model Fine-Tuning

Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa

Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health

Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...

Establishing a Conventional Linac-Based Electron Flash Beam

Authors: Christopher Bartee, Justin Riley DeFrancisco, Marcos Feijoo, Siyong Kim, Tianjun Ma

Affiliation: Blue Physics LLC, Virginia Commonwealth University

Abstract Preview: Purpose: Irradiation with FLASH has been shown to decrease normal tissue toxicity while maintaining similar tumor control. To advance FLASH into the clinic, more preclinical investigations are first n...

Evaluating Normal Tissue Toxicity Following Pulsed Low Dose Rate Radiotherapy

Authors: Shahabeddin mostafanazhad Aslmarand, Lili Chen, Dusica Cvetkovic, Troy A. Dos Santos, Chang Ming Charlie Ma, Dae-Myoung Yang

Affiliation: Fox Chase Cancer Center

Abstract Preview: Purpose:
Pulsed low-dose-rate radiotherapy (PLDR) has been proposed to reduce normal tissue toxicity while maintaining tumor control comparable to conventional radiotherapy (CRT). This study assess...

Evaluating the Impact of Beam Spot Spacing on Dose Rates and Field Uniformity for Small Animal Proton Ultra-High Dose Rate Irradiation

Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang

Affiliation: Cincinnati Children's Proton Therapy Center

Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...

Image-Guided Adaptive Proton Therapy for Head and Neck Cancer Using a Novel Gantry-Less System

Authors: Philip Blumenfeld, Jon Feldman, Yair Hillman, Michael Marash, Aron Popovtzer, Alexander Pryanichnikov, Shimshon Winograd, Marc Wygoda, Vered Zivan

Affiliation: Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), P-Cure Ltd./Inc., Sharett Institute of Oncology, Hadassah Medical Center, Hebrew University of Jerusalem

Abstract Preview: Purpose:
Image-guided adaptive proton therapy (IGAPT) allows tailored dose adjustments to account for anatomical and physiological changes during treatment. Recent efforts have developed a cost-eff...

Linac Based Dose-Escalated Radiation Therapy for Pancreatic Cancer: Assessing Respiratory Motion

Authors: Neal Andruska, Lianna D. DiMaso-Myers

Affiliation: Northwestern Medicine

Abstract Preview: Purpose: To provide details on how our clinic assesses respiratory motion during treatment of a pancreatic adenocarcinoma during dose escalated radiation therapy on a linear accelerator with the aid o...

Monte Carlo Evaluation of Water-Equivalent Materials for Nanowire-Based Oslds in Flash Radiotherapy

Authors: James Chun Lam Chow, Harry E Ruda

Affiliation: University of Toronto, Princess Margaret Cancer Centre

Abstract Preview: Purpose: FLASH radiotherapy (FLASH-RT) with dose rate greater than 40 Gy/s, has demonstrated potential in reducing normal tissue toxicity while maintaining tumor control. However, accurate and reliabl...

Optimizing Fractionation Schedules for De-Escalation Radiotherapy in Head and Neck Cancers Using Deep Reinforcement Learning

Authors: Zhongjie Lu

Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine

Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...

Proton Vs Photon Therapy for Stereotactic Arrhythmia Radioablation of Ventricular Tachycardia

Authors: Chih-Wei Chang, Kristin A Higgins, Xiaojun Jiang, Pretesh Patel, Justin R. Roper, Keyur Shah, Sibo Tian, Zhen Tian, Yinan Wang, Xiaofeng Yang, Jun Zhou

Affiliation: Department of Radiation Oncology, City of Hope Cancer Center Atlanta, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Ventricular tachycardia (VT) is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. Stereotactic arrhythmia...

Standardized MRI-CT Hybrid Workflow for High-Dose-Rate Image-Guided Adaptive Brachytherapy in Cervical Cancer: Aapm TG-303 Implementation

Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni

Affiliation: Mercy Hospital Springfield

Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...