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Results for "wilcoxon signed": 26 found

A Dosimetric Analysis between Surgically Targeted (STaRT) Radiation Therapy and External Beam Stereotactic Radiation Therapy for Glioblastoma Resection Cavities

Authors: Jamieson Baker, Emel Calugaru, Yijian Cao, Jenghwa Chang, Jessica Jung, Jian Liu, Cindy Pham, Anurag Sharma, John Starner, Ching-Ling Teng, Michael A. Trager, Gabriella Wernicke

Affiliation: Northwell, Northwell Health, Radiation Medicine, Northwell Health, Hofstra University Medical Physics Program

Abstract Preview: Purpose: Our hospital network has options to treat recurrent glioblastoma (GBM) with surgically targeted Cesium-131 brachytherapy, external beam stereotactic radiotherapy (SRT) with Varian TrueBeam, H...

Advancing Deep Segmentation Accuracy in CBCT for Radiotherapy Via Robust Scatter Mitigation: First Results from a Pilot Trial

Authors: Cem Altunbas, Farhang Bayat, Roy Bliley, Rupesh Dotel, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi

Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic, University of Colorado Anschutz Medical Campus

Abstract Preview: Purpose: Automatic segmentation of anatomical structures in CBCT images is key to enabling dose delivery monitoring and online plan modifications in radiotherapy. However, poor image quality can degra...

Advancing Post-Radiotherapy Toxicity Extraction: A Novel Privacy-Preserving, Parameter-Efficient Language Model Fine-Tuning

Authors: Hassan Bagher-Ebadian, Indrin J. Chetty, Mohamed Elshaikh, Ahmed I Ghanem, Mohammad M. Ghassemi, Reza Khanmohammadi, Benjamin Movsas, Shayan Siddiqui, Kundan S Thind, Jawad Turfa

Affiliation: Michigan State University, Department of Radiation Oncology,Cedars-Sinai Medical Center, Department of Radiation Oncology, Henry Ford Health-Cancer, Detroit, MI and Alexandria Department of Clinical Oncology, Faculty of Medicine, Alexandria University, Henry Ford Health

Abstract Preview: Purpose: Extracting late radiotherapy-induced toxicities from free-text notes using natural language processing is complicated by negative symptom identification, computational demands, and data priva...

Advancing Thoracic Synthetic CT Images with Enhanced Cyclegan for Adaptive Radiotherapy Applications

Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu

Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...

Assessing an Improvement to Hyperarc SRS Planning: Comparing the Efficiency Index of Hyperarc Alone Vs Hyperarc + Surface Area Informed Optimization

Authors: Ivan L. Cordrey, Dharmin D. Desai, Ellis Lee Johnson

Affiliation: Cumberland Medical Center - Cancer Center, University of Kentucky, Varian Advanced Oncology Solutions

Abstract Preview: Purpose: HyperArc (HA) is known to produce a high quality SRS plan. Adding Surface Area Informed Optimization (SAIO) to HA has been shown to improve plan quality metrics R50% and the Conformality Inde...

Black Bone MRI As a Surrogate for CT to Detect Intensity Differences in Mandible Sub-Volumes

Authors: Cem Dede, Clifton David Fuller, Renjie He, Laia Humbert Vidan, Stephen Y. Lai, Amy Moreno, Mohamed Naser, Kareem Abdul Wahid, Natalie A West

Affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center; The University of Texas MD Anderson Cancer Center UTHealth Houston Graduate School of Biomedical Sciences, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: Head and neck cancers (HNC) treated with radiation therapy can result in radiation-induced bone injury. In CT, changes in radiodensity correlate to changes in bone integrity. Most studies use...

Comparison of Frame-Based and Frameless Gamma Knife Coordinate Spaces for Treatment of Trigeminal Neuralgia

Authors: Tatiana Bejarano, Omer Gal, Alonso N. Gutierrez, Matthew D. Hall, Rupesh Kotecha, Yongsook C. Lee, Michael W. McDermott, Minesh P. Mehta, Robert H. Press, Carlos M. Rivera, Ranjini P. Tolakanahalli, D. Jay J. Wieczorek

Affiliation: Miami Cancer Institute, Baptist Health South Florida

Abstract Preview: Purpose:
Gamma Knife (GK) cone beam computed tomography-based stereotactic reference (CBCTRef) combined with pre-planning MRI, provides a flexible alternative to the historical frame-based localiza...

Developing Patient-Specific Functional Atlases with Inverse Distance Weighting of MR Images

Authors: Chibawanye I. Ene, Sherise D. Ferguson, Ping Hou, Vinodh A. Kumar, Ho-Ling Anthony Liu, Kyle R. Noll, Sujit S. Prabhu, Jian Ming Teo, Max Wintermark

Affiliation: Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Department of Neuroradiology, The University of Texas MD Anderson Cancer Center, Department of Neurosurgery, The University of Texas MD Anderson Cancer Center, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose:
Functional brain atlases are used to guide clinical functional MRI (fMRI) analyses. Imprecise assertions may introduce the ecological fallacy as atlases are reflective of the constituent c...

Diffusion Model-Based Motion Correction in Portable Computed Tomography for Brain: Human Observer Study

Authors: Rajiv Gupta, Rehab Naeem Khalid, Min Lang, Michael H Lev, Quirin Strotzer, Matthew Tivnan, Maryam Vejdani-Jahromi, Dufan Wu, Siyeop Yoon, Chen Zhennong

Affiliation: Massachusetts General Hospital

Abstract Preview: Purpose: Patient motion is a major source of artifacts in portable brain CT due to the slow scanning speed. A diffusion model was developed to reduce these motion artifacts. This work aims to assess t...

Dosimetric Evaluation of Clinical Venezia Hybrid Applicator Plans Using a TG-186 Model-Based Dose Calculation Algorithm

Authors: Davide Brivio, Ivan M. Buzurovic, Thomas C. Harris, Desmond A. O'Farrell

Affiliation: Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology

Abstract Preview: Purpose: Cervical cancer can be treated with a brachytherapy boost following external beam radiotherapy. One applicator option is the Advanced Gynecological Applicator "Venezia" (Elekta) hybrid, consi...

Eclipse AFI Manual Planning Versus Brainlab Auto-Planning: A Comparison of SRS Plan Quality

Authors: Dharmin D. Desai, Ellis Lee Johnson, Philip J. Kallenberg, Kapil M. Mishra

Affiliation: Spectrum Medical Physics, University of Kentucky, Varian Advanced Oncology Solutions

Abstract Preview: Purpose: The “Ask For It” (AFI) manual optimization strategy has been shown to generate high quality SRS plans within Eclipse. The purpose of this work is to directly compare manually generated Eclips...

Evaluating Longitudinal Amyloid Burden Related to Alzheimer’s Disease When Transitioning between PET β-Amyloid Radiotracers

Authors: Brecca Bettcher, Tobey J Betthauser, Bradley T Christian, Sterling Johnson, Lisette LeMerise, Max McLachlan, Andrew McVea, Dhanabalan Murali, Ali Pirasteh, Matthew Zammit

Affiliation: University of Wisconsin-Madison School of Medicine and Public Health and Waisman Center

Abstract Preview: Purpose: The radiotracer [18F]NAV4694 is a desirable alternative to [11C]PiB for measuring amyloid neuropathology related to Alzheimer’s disease (AD), possessing similar imaging characteristics and fa...

Evaluation of a Commercial Metal Artifact Reduction Algorithm for IGRT in Patients with Hip Prostheses

Authors: Laura Bennett, Matthew Charles, Greg Cooley, John M. Floberg, Ryan Hutten, Elissa Khoudary, Nicholas Lynch, Kaili Ranta, Jordan M. Slagowski, Trevor Wilson

Affiliation: University of Pennsylvania, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Human Oncology, University of Wisconsin-Madison, University of Wisconsin-Madison

Abstract Preview: Purpose: To evaluate the impact of an iterative cone beam CT with metal artifact reduction (iCBCT+MAR) reconstruction algorithm (HyperSight TrueBeam 4.1, Varian Medical Systems) on image quality and s...

Expert Verification of AI-Generated Cardiac Substructures and Dosimetric Differences between Auto-Contoured and Manually Delineated Contours

Authors: Stephen R. Bowen, Richard Cheng, Kylie Kang, Janice Kim, Ana Paula Santos Lima, Dominic A. Maes, Juergen Meyer, Karen Ordovas, Kerry Reding

Affiliation: Department of Radiation Oncology, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiology, University of Washington, Division of Cardiology, University of Washington, Department of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington

Abstract Preview: Purpose: Artificial intelligence (AI)-based auto-segmentation tools can increase the efficacy and reproducibility of radiotherapy (RT) treatment planning. This study evaluates the quality of AI-genera...

Feasibility and Dosimetric Impact of Intensity-Modulated Radiotherapy for Cervical Cancer Patients in Nepal: A Retrospective Analysis

Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand

Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center

Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...

Hypersight-Archer Study: Improved Target Coverage and Organ-at-Risk Sparing Via Adaptive Radiotherapy of Head and Neck Cancer Using Direct-Dose Calculation on Cone Beam CT

Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan

Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health

Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...

Integrated Catheter Position and Dwell Time Optimization for Focal Dose Escalation in Prostate HDR Brachytherapy

Authors: Bryan Bednarz, John M. Floberg, Joseph B. Schulz, Jordan M. Slagowski

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison

Abstract Preview: Purpose: Catheter placement for high-dose-rate brachytherapy (HDR BT) is clinician dependent and potentially suboptimal for delivering simultaneous integrated boosts to intraprostatic gross tumor volu...

Lung Nodule Volume Estimation: Performance of Conventional Energy-Integrating and Cdznte-Photon-Counting CT Using Hybrid Reconstruction Method

Authors: Gisell Ruiz Boiset, Paulo ROBERTO Costa, Luuk J Oostveen, Elsa Bifano Pimenta, Ioannis Sechopoulos, Alessandra Tomal

Affiliation: Radboud University Medical Center, University of São Paulo (USP), Institute of Physics, Universidade Estadual de Campinas. Instituto de Física Gleb Wataghin

Abstract Preview: Purpose: The study evaluated the accuracy and precision of lung nodule volume measurements, specifically solid nodules (SNs) and ground-glass opacities (GGOs) in different imaging settings.
Methods...

Multi-Path Deep Learning Model for Predicting Post-Radiotherapy Functional Liver Imaging in Patients with Hepatocellular Carcinoma

Authors: Smith Apisarnthanarax, Stephen R. Bowen, Sunan Cui, Jie Fu, Clemens Grassberger, Yulun He, Yejin Kim, Matthew J. Nyflot, Sharon Pai

Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Washington, University of Washington, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Physics, University of Washington, University of Washington and Fred Hutchinson Cancer Center

Abstract Preview: Purpose: 99mTc-sulfur colloid SPECT imaging enables quantitative assessment of voxel-wise liver function in patients with hepatocellular carcinoma (HCC). Accurately predicting post-radiotherapy (RT) l...

Patient-Specific Treatment Plan Optimization through Intentional Deep Overfit Learning As a Warm Start for Longitudinal Adaptive Radiotherapy

Authors: Wouter Crijns, Frederik Maes, Loes Vandenbroucke, Liesbeth Vandewinckele

Affiliation: Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven; Department of Radiation Oncology, UZ Leuven, Department ESAT/PSI, KU Leuven; Medical Imaging Research Center, UZ Leuven, Department of Oncology, Laboratory of Experimental Radiotherapy, KU Leuven

Abstract Preview: Purpose: To explore intentional deep overfit learning (IDOL) to exploit the initial treatment plan to predict an adaptive radiotherapy plan.
Methods: A conditional generative adversarial network is...

Prostate Brachytherapy Training – a Virtual Approach

Authors: Fahad Alam, Douglas A Hoover, Raffi Karshafian, Andrew Loblaw, Lucas Mendez, Lucas Mendez, Gerard Morton, Humza Nusrat, Moti R. Paudel, Mackenzie Smith, Amandeep Tagger, Anton Varlukhin

Affiliation: Odette Cancer Center, Sunnybrook Health Sciences Center, Department of Anesthesiology, Temerty Medicine, University of Toronto, Department of Physics, Toronto Metropolitan University, Department of Radiation Oncology, Temerty Medicine, University of Toronto, Department of Radiation Oncology, London Health Sciences Centre

Abstract Preview: Purpose: Prostate brachytherapy utilization has declined, due in part to limitations seen with in-person training including time and space constraints in the operating room. Virtual reality addresses ...

Proton Vs Photon Therapy for Stereotactic Arrhythmia Radioablation of Ventricular Tachycardia

Authors: Chih-Wei Chang, Kristin A Higgins, Xiaojun Jiang, Pretesh Patel, Justin R. Roper, Keyur Shah, Sibo Tian, Zhen Tian, Yinan Wang, Xiaofeng Yang, Jun Zhou

Affiliation: Department of Radiation Oncology, City of Hope Cancer Center Atlanta, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University

Abstract Preview: Purpose: Ventricular tachycardia (VT) is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. Stereotactic arrhythmia...

Quantifying the Impact of Tissue Inhomogeneities on Calculated Dosimetry within LDR Brachytherapy

Authors: Fatemeh Akbari, Deidre Batchelar, Luc Beaulieu, Nathan E. Becker, Juanita Crook, Dakota Mckeown, Matthew Jonathan Muscat, Rowan M. Thomson

Affiliation: Département de physique, de génie physique et d'optique, Université Laval, BC Cancer Agency, UBC, Carleton University, BC Cancer - Kelowna, BC Cancer

Abstract Preview: Purpose:
To study the effects of inter-seed attenuation and tissue inhomogeneities on dose-volume metrics of critical structures in prostate low-dose-rate (LDR) permanent seed implant brachytherapy...

Robust Evaluation of Rotational Uncertainties on Single-Isocenter Multi-Target Stereotactic Radiosurgery Hyperarc Treatment

Authors: Albert Admasu, Kayla Alfonso, Maria de la Luz De Ornelas, Nesrin Dogan, Eric Mellon, Yunze Yang

Affiliation: University of Miami, Department of Radiation Oncology, University of Miami, University of Miami Sylvester Comprehensive Cancer Center

Abstract Preview: Purpose: Rotational uncertainties in single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) HyperArc treatments can cause additional target displacement, potentially degrading overall pl...

Simultaneous Synthesis of Lung Perfusion and Ventilation Images from CT Using a Dual-Decoder Residual Attention Network for Lung Disease Diagnosis

Authors: Li-Sheng Geng, David Huang, Haoze Li, Xi Liu, Meng Wang, Tianyu Xiong, Ruijie Yang, Weifang Zhang, Meixin Zhao

Affiliation: School of Physics, Beihang University, Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Department of Radiation Oncology, Peking University Third Hospital, Department of Nuclear Medicine, Peking University Third Hospital, Medical Physics Graduate Program, Duke Kunshan University

Abstract Preview: Purpose: This study aimed to develop a deep learning-based framework for simultaneously generating lung perfusion and ventilation images from three-dimensional computed tomography (3D CT) images.
M...

The Effect of 2D Antiscatter Grid-Based CBCT on Tissue Visualization in the Prostate Region: An Observer Study on Tissue Delineation Accuracy

Authors: Cem Altunbas, Adam Avant, Farhang Bayat, Roy Bliley, Ian Boor, Brian Kavanagh, Uttam Pyakurel, Tyler Robin, Ryan Sabounchi

Affiliation: Department of Radiation Oncology, University of Colorado School of Medicine, Taussig Cancer Center, Cleveland Clinic

Abstract Preview: Purpose: Improved soft tissue visualization plays an important role in target localization and treatment plan adaptation in CBCT-guided radiotherapy. In this work, a novel CBCT approach, 2D antiscatte...